This issue of Endocrinology and Metabolism Clinics, devoted to Lipids, is edited by Dr. Donald A. Smith. Articles in this issue include: Advanced Lipoprotein Testing; Improving Cardiovascular Risk Assessment: Coronary calcium scor and CT coronary imaging; Understanding HDL; Statin Strategies for Maximizing Public Health: benefits and harms; Cellular Cholesterol Regulation: SREBP and miRNA; Mediterranean Diet - the best diet for CV protection?; Pediatric Lipidology: An Earlier Approach; Newer LDL-lowering Therapies; and Statin Combination Therapies.

Whether you are a student of biomedicine or medicine, trainee, resident, or endocrinology fellow, Clinical Endocrinology provides you with the core information you need to understand this notoriously complex subject. The book describes the biochemistry, physiology, and anatomy that underpin clinical practice and then integrates genuine clinical cases to show the application of this basic science in diagnosis and treatment. Key features include: a flowing narrative that leads you through the basic science boxes that provide core reference information advanced boxes that provide additional material suitable for residents and fellows case studies that link with the text and describe the presentation, diagnosis, and management of real patients further clinical material that builds on the basic science and describes the causes of endocrine disorders, their clinical features, and treatment options coverage of the latest advances and discoveries self-assessment questions to test understanding The book is lavishly illustrated throughout with line drawings and clinical photographs. The authors, one a scientist and the other a clinician, guide you through the complexities of physiology and biochemistry so that you can understand the nature and management of endocrine pathologies. At all times they relate basic science to clinical medicine in a clear and lucid style that is both practical and clinically relevant. From reviews: "Clinical Endocrinology is very well written and beautifully illustrated." Lancet Diabetes Endocrinology, January 2013 "All in all this is an excellent, essential textbook which does the job admirably in terms of synthesising the essence of human physiology and excreting a patient-centred approach to addressing the clinical manifestations of endocrine hypo- and hyper-function." The Endocrinologist, December 2013 "This book would appeal particularly to medical students or endocrinologists in training... [It] provides a useful review of endocrinology in a comprehensive manner starting from basic science principles and ending with clinical applications." Doody's Notes, May 2013 About the authors: Professor Saffron Whitehead is Professor of Endocrine Physiology at St George's Medical School, University of London Dr John Miell is a Consultant Endocrinologist at University Hospital Lewisham, London

This issue of Thoracic Surgery Clinics is devoted to "Clinical Management of Neuroendocrine Tumors of the Lung" and is edited by Dr. Pier Luigi Filosso. Articles in this outstanding issue include: Pathology of neuroendocrine tumors, Clinical and radiological presentation of neuroendocrine tumors of the lung, Neuroendocrine tumors and endocrine syndromes, The significance of histology: typical and atypical bronchial carcinoids, Surgical management of well-differentiated lung neuroendocrine tumors, Surgical management of large cell neuroendocrine carcinoma (LCNC) of the lung, The role of surgery in small cell carcinoma, Management of thymic neuroendocrine tumors, Medical treatment of advanced thoracic neuroendocrine tumors, Radiometabolic treatment of advanced neuroendocrine tumors, Biological and clinical prognostic factors in thoracic neuroendocrine tumors, and more!

This Otolaryngologic Clinics' publication's intent is to provide standard and state of the art clinician performed thyroid ultrasound and ultrasound guided FNA technique. The subject area is evolving rapidly with new technologies being incorporated. This title integrates thyroid cytology, FNA and Ultrasound Guided FNA with inclusion of diagnostic molecular testing. Clinical Thyroid Molecular Testing has ushered in a new era to the diagnosis, management and prognostication of thyroid nodules. The discussion of this highly clinically applicable subject is described in terms of diagnostic process. This is a thyroid neoplasm clinical "game changer? for the General Otolaryngologist, Head and Neck Surgeon, General Surgeon, Endocrinologist, Pathologist, and Radiologist. This testing maximizes the number of patients who have cancer to receive the correct therapeutic surgery appropriately and minimizes the number of patients who do not need surgery (and avoid the potential complications and surgery) because they do not have cancer. Surgical management and prognostication have far reaching implications with fine needle aspiration driven molecular markers. Some topics include: Clinical evaluation of the thyroid nodule; Thyroid cytology; Clinician performed thyroid ultrasound; Clinician performed thyroid ultrasound guided FNA; Thyroid cancer molecular laterations - what the surgeon should know; Thyroid cancer multi-gene expression - what the surgeon needs to know; Incorporating molecular testing into your thyroid practice - five experts discuss; and others.

Managing and treating patients with thyroid issues accounts for about 30% of an endocrinologist's practice. The issue will be divided into two parts: thyroid cancer and other major disorders. Articles will cover new information on TSH and radioiodine therapy to treat thyroid cancer, as well as best practices for managing hypothyroidism, Graves disease and thyroiditis.

Editor Peter Mazzaglia and authors review the current management and procedures in endocrine surgery. Articles will cover: central compartment lymph node dissection for papillary thyroid cancer; evaluation of thyroid incidentaloma; the role of genetic markers in the evaluation and management of thyroid nodules; medical therapy for advanced forms of thyroid cancer; follicular lesions of the thyroid; controversy over radio-iodine ablation: who benefits?; minimizing cost while maximizing success in the pre-operative localization strategy for primary hyperparathyroidism; operative treatment for primary hyperparathyroidism; evaluation of adrenal incidentalomas: biochemical and radiographic characterization; hyperaldosteronism: diagnosis, lateralization, and treatment; subclinical Cushing's syndrome; adrenocortical cancer update; and pancreatic neuroendocrine tumors.

A thyroidectomy is an operation that involves the surgical removal of all or part of the thyroid gland. This book is a guide to thyroidectomy for surgeons and endocrinologists. Beginning with an overview of the cross-sectional anatomy of the neck, the next chapters explain patient positioning and skin incision. The following sections discuss surgical techniques for different sections of the thyroid and for different disorders. Authored by internationally recognised experts in the field, the text is further enhanced by clinical photographs and diagrams illustrating surgical procedures, anatomical dissections, and schematic representations. Key points Guide to thyroidectomy for surgeons and endocrinologists Covers surgical techniques for different sections of the thyroid Authored by internationally recognised experts Highly illustrated with surgical images, anatomical dissections and schematic representations

This book is a comprehensive guide to endocrinology for clinicians and trainees. Beginning with an overview of the endocrine system, the text then describes the chemistry and mechanism of hormones and their clinical significance. The following sections discuss the role of different organs in the endocrine system, including glands, the pancreas, and gonads. The next chapters cover hormones in other organs such as the gastrointestinal tract, liver, kidney and heart. The book concludes with discussion on endocrine tumours and growth factors. Key points Comprehensive guide to endocrinology for clinicians and trainees In depth discussion on chemistry and mechanism of hormones Examines role of different organs in the endocrine system Includes chapters on endocrine tumours and growth factors

The 3rd edition of Hormones offers a comprehensive treatment of the hormones of humans all viewed from the context of current theories of their action in the framework of our current understanding their physiological actions as well as their molecular structures, and those of their receptors. This new edition of Hormones is intended to be used by advanced undergraduates and graduate students in the biological sciences. It will also provide useful background information for first year medical students as they engage in studies which are increasingly problem-based rather than discipline-focused. As the field of endocrinology itself has expanded so much in the past two decades, the up-to-date presentation of the basics presented in this book will be a solid foundation on which more specialized considerations can be based. New to this Edition: Coverage, for the first time of the following hormones; ghrelin, oxyntomodulin, kisspeptin, adrenomedullin, FGF23, erythropoietin, VIP and extended coverage of NO. Coverage of the hypothalamus has been integrated with the anterior pituitary because of the intimate functional and relationship between the two. The chapter on the thymus has been eliminated as more properly belonging in a book on immunology. Consideration of the role of hormones in cancer has been integrated into the chapters on the relevant hormones. Each of these areas occupies a unique niche in our understanding of the biological world and is part of the universality of signaling systems and how they govern biological systems.
New full color format includes over 600 full color, completely redrawn imagesCompanion web site will host all images from the book as PPT slides and .jpeg filesAll chapters have been completely updated and revitalized. Coverage of the hypothalamus has been integrated into the anterior pituitary chapter and coverage of the thymus has been eliminated and left to immunology textbooks

This issue of Endocrinology Clinics brings the reader up to date on the important advances in research surrounding acute diabetic complications. Guest edited by Leonid Poretsky and Eliana Liao, the topics covered include retinopathy, neuropathy, gastrointestinal complications, diabetic foot, dental complications, dermatologic complications, and more.

Encyclopedia of Gastroenterology, Second Edition, Four Volume Set provides a comprehensive and concise reference on all aspects of gastroenterology and hepatology, including the organs in the gastrointestinal system, their functions in health and disease, and strategies or procedures to resolve or prevent problems and disease. This concise, up-to-date information includes comprehensive sections on the impact of nutrition, gastrointestinal microbiota, lifestyle, commonly used drugs, and surgical procedures on health and disease. Since the first edition, attention to the roles of nutrition and gastrointestinal microorganisms (microbiota, formerly Microbiota) in health and disease has skyrocketed. In addition, an entirely new section on obesity and diabetes is included.

Iron Metabolism, Volume 110, the latest release in the Vitamins and Hormones series first published in 1943, covers the field of hormone action, vitamin action, X-ray crystal structure, physiology and enzyme mechanisms, with this release focusing on topics relating to hepcidin, bacterial infection, and iron overload, the role of heparan sulfates in hepcidin regulation, hepcidin CDNA and human gene sex hormones, growth factors and hepcidin, HFE gene polymorphisms and hereditary hemochromatosis, hepcidin and il-1beta, hepcidin-ferroportin axis, cardiomyocyte hepcidin, adipocyte iron, leptin and hepcidin, regulators of hepcidin expression, and much more.

This issue of Endocrinology Clinics brings the reader up to date on the important advances in research in endocrinology topics covered include reproducnd psychiatry. Guest edited by Eliza Geer, the topics covered include stress, sleep disorders, antipsychotic medications, eating disorders, insulin resistance, drug and alcohol addictions and more.

This issue of Endocrinology Clinics brings the reader up to date on the important advances in research surrounding the role of aging on the endocrine system. Guest edited by Anne Cappola, the topics covered include reproductive aging in women, thyroid disorders, testosterone administration, osteoporosis in older adults, hormonal therapeutics and more.

This issue of Endocrinology Clinics brings the reader up to date on the important advances in research surrounding the neuroendocrine control of metabolism. Guest edited by Christoph Buettner, the topics covered include leptin signaling, hypothalmic inflammation, hypoglycemia awareness, perinatal programming of metabolic disease, substrates, and more.

This issue of Endocrinology Clinics brings the reader up do date on the current standards and important advances in insulin therapy.? The following clinical topics are discussed: types of insulins, including new insulins; goals of therapy; pathophysiology of, and insulin treatment in type1 and type 2 diabetes mellitus; pumps and glucose sensors; alternative insulin delivery; patient and provider insulin resistance; inpatient insulin therapy; insulin therapy in pregnancy; and pediatric insulin therapy.

Every surgical subspecialty has been rapidly developing with establishment of the board certification. The Division of Endocrine Surgery (DES) of the European Board of Surgery has defined the curriculum for Endocrine Surgery to include thyroid, parathyroid, adrenal and GEP-NET surgery, and handles accreditation in Endocrine Surgery. The first examinations in Endocrine Surgery in Europe have been introduced in 2003. The main goal of the exam is to maintain a uniform and high standard of endocrine surgical professionalism across the Europe. This book was completed with the expectation that it would benefit all European surgeons looking to be certified in Endocrine Surgery. Additionally, surgeons from the United States and other non-EU countries we hope will also benefit from this book. There is a need for a specialized book that reviews evidence based endocrine surgery that aligns itself with current curriculum standards in the field. The book contains knowledge that is expected to be known on the board examination of the DES. In general, chapters start with a patient's case followed by questions. The subsequent comprehensive yet concise main text provides all the information needed for a successful DES exam and cites important references. After the patient case and questions, the text goes on to define the condition, the standard of care approach to establish the diagnosis, perform diagnostic tests of choice, review evidence-based treatment options including medical therapy, preparation for surgery. The chapters conclude with follow up care and long term outcomes. The topics discussed within this book closely follow the curriculum of the European Board of Surgery Examination. Written by experts in the field, Endocrine Surgery Comprehensive Board Exam Guide is a valuable source of preparation for the Endocrine Surgery examination and brings Endocrine Surgery to a higher level of expertise by helping to raise the standard of training for future endocrine surgeons.

This issue of Endocrinology and Metabolism Clinics provides essential updates across the spectrum of pediatric endocrinology. Topics covered include Prevention of type 1 and type 2 diabetes mellitus; genetics of growth; diagnosis in prepubescent girls; Turner and Noonan Syndromes; thyroid function in Down Syndrome; chronic disease; effects of ADHD treatment on growth; Vitamin D and bone health; use of statins; and obesity prevention.

This issue of the Neurosurgery Clinics of North America, Guest Edited by Drs. Manish Aghi and Lewis Blevins, is devoted to Management of Pituitary Tumors.? Experts in the field have assembled to provide articles on Imaging of the pituitary and parasellar region; Management of Incidentally Found Nonfunctional Pituitary Tumors; Endoscopic Surgery for Pituitary Tumors; Prolactinomas - Medical versus Surgical Management; Neurosurgery for Cushing's Disease; Postoperative radiotherapy and stereotactic radiosurgery for pituitary tumors; Management options for persistent postoperative acromegaly; Medical management of persistent and recurrent Cushing's disease; Management of Large Aggressive Nonfunctional Pituitary Tumors - Experimental Medical Options when Surgery and Radiation Fail; Pituitary Carcinoma; Visual Outcomes after Surgery For Nonfunctional Adenomas Causing Visual Compromise; and Hypopituitarism and Central Diabetes Insipidus: Peri-Operative Diagnosis and Management.

The Year Book of Endocrinology brings you abstracts of the articles that reported the year's breakthrough developments in endocrinology carefully selected from more than 500 journals worldwide. Expert commentaries evaluate the clinical importance of each article and discuss its application to your practice. Topics such as Diabetes, Lipoproteins and Ahterosclerosis, Obesity, Thyroid, Calcium and Bone Metabolism, Adrenal Cortex, and Neuroendocrinology are represented highlighting the most current and relevant articles in the field.

This issue of Endocrinology and Metabolism Clinics provides a comprehensive review of osteoporosis written by the world's leading experts. Topics include new mechanistic insights into pathophysiology; bisphosphonates; combination therapy; atypical fractures; non-BP anti resorbers; anabolic therapies; calcium; the impact of Vitamin D on bones; extraskeletal effects of Vitamin D; glucocorticoid osteoporosis; relation to anorexia nervosa, coeliac disease, and diabetes; and male osteoporosis.

This issue of Endocrinology Clinics, authored by experts worldwide, provides essential updates about insulin-like growth factors (IGFs).? The physiology is examined, including the latest in what we have learned from animal models as well as humans.? The issue also covers IGFs and IGF system in the following: growth disorders; adipogenesis and obesity; muscle function and disease; bone; cancer; cardiac function and disease; normal and diseased kidney; peripheral nervous systems; gastrointestinal diseases; diabetes and metabolism; and IGF-1 central/degenerative diseases.

This issue of Medical Clinics of North America provides the latest essential updates on thyroid disorders and diseases.? Topics covered include the following: thyroid synthesis and physiology; hyperthyroidism; hypothyroidism; thyroid nodules; goiter; differentiated thyroid cancer; subacute, silent, and postpartum thyroiditis; thyroid and pregnancy; thyroid and the elderly; medications and thyroid hormones; thyroid and the heart; thyroid and lipids; and Graves' ophthalmology.

This issue of Endocrinology Clinics covers essential updates in a range of common endocrine disorders that are of special concern during pregnancy, as well as endocrine problems that can arise due to pregnancy.? A variety of thyroid, pituitary, adrenal, and hypertensive disorders are covered, as well as calcium and bone metabolism disorders during pregnancy and lactation.? Diagnosis and treatment of gestational diabetes, and pregestational diabetes are addressed.? Iodine disorders in pregnancy and lactation are covered.? Hyperprolactinemia and infertility are also addressed.? Special concerns of obesity in women with reproductive dysfunction are considered.? An in-depth guide to achieving a successful pregnancy with PCOS is provided

The articles in this issue give an overview of current issues facing the diagnosis and treatment of diseases involving? endocrinology and metabolism. Dr. Rapaport has compiled experts in this field to write state-of-the art clinical reviews on newborn screening, congenital hypothyroidism, neonatal endocrinology, obesity, and? the metabolic syndrome in pediatrics. Also included are articles devoted to growth issues, gonadal disorders, and diabetes as well as initiatives to prevent it.