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Books > Science & Mathematics > Mathematics > Applied mathematics > General

Stochastic Analysis with Financial Applications - Hong Kong 2009 (Hardcover, 2011 ed.): Arturo Kohatsu-Higa, Nicolas Privault,... Stochastic Analysis with Financial Applications - Hong Kong 2009 (Hardcover, 2011 ed.)
Arturo Kohatsu-Higa, Nicolas Privault, Shuenn-Jyi Sheu
R2,720 Discovery Miles 27 200 Ships in 18 - 22 working days

Stochastic analysis has a variety of applications to biological systems as well as physical and engineering problems, and its applications to finance and insurance have bloomed exponentially in recent times. The goal of this book is to present a broad overview of the range of applications of stochastic analysis and some of its recent theoretical developments. This includes numerical simulation, error analysis, parameter estimation, as well as control and robustness properties for stochastic equations. The book also covers the areas of backward stochastic differential equations via the (non-linear) G-Brownian motion and the case of jump processes. Concerning the applications to finance, many of the articles deal with the valuation and hedging of credit risk in various forms, and include recent results on markets with transaction costs.

New Horizons in Fundamental Physics (Hardcover, 1st ed. 2017): Stefan Schramm, Mirko Schafer New Horizons in Fundamental Physics (Hardcover, 1st ed. 2017)
Stefan Schramm, Mirko Schafer
R3,509 Discovery Miles 35 090 Ships in 10 - 15 working days

This volume presents the state-of-the-art in selected topics across modern nuclear physics, covering fields of central importance to research and illustrating their connection to many different areas of physics. It describes recent progress in the study of superheavy and exotic nuclei, which is pushing our knowledge to ever heavier elements and neutron-richer isotopes. Extending nuclear physics to systems that are many times denser than even the core of an atomic nucleus, one enters the realm of the physics of neutron stars and possibly quark stars, a topic that is intensively investigated with many ground-based and outer-space research missions as well as numerous theoretical works. By colliding two nuclei at very high ultra-relativistic energies one can create a fireball of extremely hot matter, reminiscent of the universe very shortly after the big bang, leading to a phase of melted hadrons and free quarks and gluons, the so-called quark-gluon plasma. These studies tie up with effects of crucial importance in other fields. During the collision of heavy ions, electric fields of extreme strength are produced, potentially destabilizing the vacuum of the atomic physics system, subsequently leading to the decay of the vacuum state and the emission of positrons. In neutron stars the ultra-dense matter might support extremely high magnetic fields, far beyond anything that can be produced in the laboratory, significantly affecting the stellar properties. At very high densities general relativity predicts the stellar collapse to a black hole. However, a number of current theoretical activities, modifying Einstein's theory, point to possible alternative scenarios, where this collapse might be avoided. These and related topics are addressed in this book in a series of highly readable chapters. In addition, the book includes fundamental analyses of the practicalities involved in transiting to an electricity supply mainly based on renewable energies, investigating this scenario less from an engineering and more from a physics point of view. While the topics comprise a large scope of activities, the contributions also show an extensive overlap in the methodology and in the analytical and numerical tools involved in tackling these diverse research fields that are the forefront of modern science.

Networks of Echoes - Imitation, Innovation and Invisible Leaders (Hardcover, 2014 ed.): Bruce J. West, Malgorzata Turalska,... Networks of Echoes - Imitation, Innovation and Invisible Leaders (Hardcover, 2014 ed.)
Bruce J. West, Malgorzata Turalska, Paolo Grigolini
R3,670 R1,917 Discovery Miles 19 170 Save R1,753 (48%) Ships in 10 - 15 working days

"Networks of Echoes: Imitation, Innovation and Invisible Leaders" is a mathematically rigorous and data rich book on a fascinating area of the science and engineering of social webs. There are hundreds of complex network phenomena whose statistical properties are described by inverse power laws. The phenomena of interest are not arcane events that we encounter only fleetingly, but are events that dominate our lives. We examine how this intermittent statistical behavior intertwines itself with what appears to be the organized activity of social groups. The book is structured as answers to a sequence of questions such as: How are decisions reached in elections and boardrooms? How is the stability of a society undermined by zealots and committed minorities and how is that stability re-established? Can we learn to answer such questions about human behavior by studying the way flocks of birds retain their formation when eluding a predator? These questions and others are answered using a generic model of a complex dynamic network one whose global behavior is determined by a symmetric interaction among individuals based on social imitation. The complexity of the network is manifest in time series resulting from self-organized critical dynamics that have divergent first and second moments, are non-stationary, non-ergodic and non-Poisson. How phase transitions in the network dynamics influence such activity as decision making is a fascinating story and provides a context for introducing many of the mathematical ideas necessary for understanding complex networks in general. The decision making model (DMM) is selected to emphasize that there are features of complex webs that supersede specific mechanisms and need to be understood from a general perspective. This insightful overview of recent tools and their uses may serve as an introduction and curriculum guide in related courses."

Numerical Methods for Differential Equations, Optimization, and Technological Problems - Dedicated to Professor P. Neittaanmaki... Numerical Methods for Differential Equations, Optimization, and Technological Problems - Dedicated to Professor P. Neittaanmaki on His 60th Birthday (Hardcover, 2013 ed.)
Sergey Repin, Timo Tiihonen, Tero Tuovinen
R5,521 R4,930 Discovery Miles 49 300 Save R591 (11%) Ships in 10 - 15 working days

This book contains the results in numerical analysis and optimization presented at the ECCOMAS thematic conference "Computational Analysis and Optimization" (CAO 2011) held in Jyvaskyla, Finland, June 9-11, 2011. Both the conference and this volume are dedicated to Professor Pekka Neittaanmaki on the occasion of his sixtieth birthday. It consists of five parts that are closely related to his scientific activities and interests: Numerical Methods for Nonlinear Problems; Reliable Methods for Computer Simulation; Analysis of Noised and Uncertain Data; Optimization Methods; Mathematical Models Generated by Modern Technological Problems. The book also includes a short biography of Professor Neittaanmaki.

Advances in Mathematical Inequalities (Hardcover): Shigeru Furuichi Advances in Mathematical Inequalities (Hardcover)
Shigeru Furuichi
R4,332 Discovery Miles 43 320 Ships in 10 - 15 working days

Mathematical inequalities are essential tools in mathematics, natural science and engineering. This book gives an overview on recent advances. Some generalizations and improvements for the classical and well-known inequalities are described. They will be applied and further developed in many fields. Applications of the inequalities to entropy theory and quantum physics are also included.

Computational Continuum Mechanics of Nanoscopic Structures - Nonlocal Elasticity Approaches (Hardcover, 1st ed. 2019): Esmaeal... Computational Continuum Mechanics of Nanoscopic Structures - Nonlocal Elasticity Approaches (Hardcover, 1st ed. 2019)
Esmaeal Ghavanloo, Hashem Rafii-Tabar, Seyed Ahmad Fazelzadeh
R3,814 Discovery Miles 38 140 Ships in 18 - 22 working days

This book offers a comprehensive treatment of nonlocal elasticity theory as applied to the prediction of the mechanical characteristics of various types of biological and non-biological nanoscopic structures with different morphologies and functional behaviour. It combines fundamental notions and advanced concepts, covering both the theory of nonlocal elasticity and the mechanics of nanoscopic structures and systems. By reporting on recent findings and discussing future challenges, the book seeks to foster the application of nonlocal elasticity based approaches to the emerging fields of nanoscience and nanotechnology. It is a self-contained guide, and covers all relevant background information, the requisite mathematical and computational techniques, theoretical assumptions, physical methods and possible limitations of the nonlocal approach, including some practical applications. Mainly written for researchers in the fields of physics, biophysics, mechanics, and nanoscience, as well as computational engineers, the book can also be used as a reference guide for senior undergraduate and graduate students, as well as practicing engineers working in a range of areas, such as computational condensed matter physics, computational materials science, computational nanoscience and nanotechnology, and nanomechanics.

Qualitative Investment Decision-Making Methods under Hesitant Fuzzy Environments (Hardcover, 1st ed. 2020): Wei Zhou, Zeshui Xu Qualitative Investment Decision-Making Methods under Hesitant Fuzzy Environments (Hardcover, 1st ed. 2020)
Wei Zhou, Zeshui Xu
R2,653 Discovery Miles 26 530 Ships in 18 - 22 working days

This book describes five qualitative investment decision-making methods based on the hesitant fuzzy information. They are: (1) the investment decision-making method based on the asymmetric hesitant fuzzy sigmoid preference relations, (2) the investment decision-making method based on the hesitant fuzzy trade-off and portfolio selection, (3) the investment decision-making method based on the hesitant fuzzy preference envelopment analysis, (4) the investment decision-making method based on the hesitant fuzzy peer-evaluation and strategy fusion, and (5) the investment decision-making method based on the EHVaR measurement and tail analysis.

Management and Minimisation of Uncertainties and Errors in Numerical Aerodynamics - Results of the German collaborative project... Management and Minimisation of Uncertainties and Errors in Numerical Aerodynamics - Results of the German collaborative project MUNA (Hardcover, 2013 ed.)
Bernhard Eisfeld, Holger Barnewitz, Willy Fritz, Frank Thiele
R4,748 Discovery Miles 47 480 Ships in 10 - 15 working days

This volume reports results from the German research initiative MUNA (Management and Minimization of Errors and Uncertainties in Numerical Aerodynamics), which combined development activities of the German Aerospace Center (DLR), German universities and German aircraft industry. The main objective of this five year project was the development of methods and procedures aiming at reducing various types of uncertainties that are typical of numerical flow simulations. The activities were focused on methods for grid manipulation, techniques for increasing the simulation accuracy, sensors for turbulence modelling, methods for handling uncertainties of the geometry and grid deformation as well as stochastic methods for quantifying aleatoric uncertainties.

The Language Phenomenon - Human Communication from Milliseconds to Millennia (Hardcover, 2013 ed.): P.-M. Binder, K Smith The Language Phenomenon - Human Communication from Milliseconds to Millennia (Hardcover, 2013 ed.)
P.-M. Binder, K Smith
R2,268 R1,907 Discovery Miles 19 070 Save R361 (16%) Ships in 10 - 15 working days

This volume contains a contemporary, integrated description of the processes of language. These range from fast scales (fractions of a second) to slow ones (over a million years). The contributors, all experts in their fields, address language in the brain, production of sentences and dialogues, language learning, transmission and evolutionary processes that happen over centuries or millenia, the relation between language and genes, the origins of language, self-organization, and language competition and death. The book as a whole will help to show how processes at different scales affect each other, thus presenting language as a dynamic, complex and profoundly human phenomenon.

A Primer on Electromagnetic Fields (Hardcover, 2015 ed.): Fabrizio Frezza A Primer on Electromagnetic Fields (Hardcover, 2015 ed.)
Fabrizio Frezza
R2,456 R1,825 Discovery Miles 18 250 Save R631 (26%) Ships in 10 - 15 working days

This book is a concise introduction to electromagnetics and electromagnetic fields that covers the aspects of most significance for engineering applications by means of a rigorous, analytical treatment. After an introduction to equations and basic theorems, topics of fundamental theoretical and applicative importance, including plane waves, transmission lines, waveguides and Green's functions, are discussed in a deliberately general way. Care has been taken to ensure that the text is readily accessible and self-consistent, with conservation of the intermediate steps in the analytical derivations. The book offers the reader a clear, succinct course in basic electromagnetic theory. It will also be a useful lookup tool for students and designers.

On Gauge Fixing Aspects of the Infrared Behavior of Yang-Mills Green Functions (Hardcover, 2012 ed.): Markus Q. Huber On Gauge Fixing Aspects of the Infrared Behavior of Yang-Mills Green Functions (Hardcover, 2012 ed.)
Markus Q. Huber
R1,408 Discovery Miles 14 080 Ships in 18 - 22 working days

Quarks are the main constituents of protons and neutrons and hence are important building blocks of all the matter that surrounds us. However, quarks have the intriguing property that they never appear as isolated single particles but only in bound states. This phenomenon is called confinement and has been a central research topic of elementary particle physics for the last few decades. In order to find the mechanism that forbids the existence of free quarks many approaches and ideas are being followed, but by now it has become clear that they are not mutually exclusive but illuminate the problem from different perspectives. Two such confinement scenarios are investigated in this thesis: Firstly, the importance of Abelian field components for the low-energy regime is corroborated, thus supporting the dual superconductor picture of confinement and secondly, the influence of the Gribov horizon on non-perturbative solutions is studied.

Molecular Dynamics - Theoretical Developments and Applications in Nanotechnology and Energy (Hardcover): Lichang Wang Molecular Dynamics - Theoretical Developments and Applications in Nanotechnology and Energy (Hardcover)
Lichang Wang
R3,620 Discovery Miles 36 200 Ships in 18 - 22 working days
Infrared Thermography (Hardcover): Raghu Prakash Infrared Thermography (Hardcover)
Raghu Prakash
R3,113 Discovery Miles 31 130 Ships in 18 - 22 working days
The Elements of Operator Theory (Hardcover, 2nd ed. 2011): Carlos S. Kubrusly The Elements of Operator Theory (Hardcover, 2nd ed. 2011)
Carlos S. Kubrusly
R3,404 Discovery Miles 34 040 Ships in 18 - 22 working days

This second edition of Elements of Operator Theory is a concept-driven textbook that includes a significant expansion of the problems and solutions used to illustrate the principles of operator theory. Written in a user-friendly, motivating style intended to avoid the formula-computational approach, fundamental topics are presented in a systematic fashion, i.e., set theory, algebraic structures, topological structures, Banach spaces, and Hilbert spaces, culminating with the Spectral Theorem.

Included in this edition: more than 150 examples, with several interesting counterexamples that demonstrate the frontiers of important theorems, as many as 300 fully rigorous proofs, specially tailored to the presentation, 300 problems, many with hints, and an additional 20 pages of problems for the second edition.

*This self-contained work is an excellent text for the classroom as well as a self-study resource for researchers.

Spectral Theory and Analysis - Conference on Operator Theory, Analysis and Mathematical Physics (OTAMP) 2008, Bedlewo, Poland... Spectral Theory and Analysis - Conference on Operator Theory, Analysis and Mathematical Physics (OTAMP) 2008, Bedlewo, Poland (Hardcover, 2011 ed.)
Jan Janas, Pavel Kurasov, A. Laptev, Sergei Naboko, Gunter Stolz
R2,652 Discovery Miles 26 520 Ships in 18 - 22 working days

This volume contains the proceedings of the OTAMP 2008 (Operator Theory, Analysis and Mathematical Physics) conference held at the Mathematical Research and Conference Center in Bedlewo near Poznan. It is composed of original research articles describing important results presented at the conference, some with extended review sections, as well as presentations by young researchers. Special sessions were devoted to random and quasi-periodic differential operators, orthogonal polynomials, Jacobi and CMV matrices, and quantum graphs. This volume also reflects new trends in spectral theory, where much emphasis is given to operators with magnetic fields and non-self-adjoint problems.

The book is geared towards scientists from advanced undergraduate students to researchers interested in the recent development on the borderline between operator theory and mathematical physics, especially spectral theory for Schr dinger operators and Jacobi matrices.

Three Domain Modelling and Uncertainty Analysis - Applications in Long Range Infrastructure Planning (Hardcover, 2015 ed.):... Three Domain Modelling and Uncertainty Analysis - Applications in Long Range Infrastructure Planning (Hardcover, 2015 ed.)
Atom Mirakyan, Roland de Guio
R3,372 R1,873 Discovery Miles 18 730 Save R1,499 (44%) Ships in 10 - 15 working days

This book examines in detail the planning and modelling of local infrastructure like energy systems, including the complexities resulting from various uncertainties. Readers will discover the individual steps involved in infrastructure planning in cities and territories, as well as the primary requirements and supporting quality factors. Further topics covered concern the field of uncertainty and its synergies with infrastructure planning. Theories, methodological backgrounds and concrete case studies will not only help readers to understand the proposed methodologies for modelling and uncertainty analysis, but will also show them how these approaches are implemented in practice.

Fundamental Mathematical Structures of Quantum Theory - Spectral Theory, Foundational Issues, Symmetries, Algebraic Formulation... Fundamental Mathematical Structures of Quantum Theory - Spectral Theory, Foundational Issues, Symmetries, Algebraic Formulation (Hardcover, 1st ed. 2019)
Valter Moretti
R2,388 Discovery Miles 23 880 Ships in 10 - 15 working days

This textbook presents in a concise and self-contained way the advanced fundamental mathematical structures in quantum theory. It is based on lectures prepared for a 6 months course for MSc students. The reader is introduced to the beautiful interconnection between logic, lattice theory, general probability theory, and general spectral theory including the basic theory of von Neumann algebras and of the algebraic formulation, naturally arising in the study of the mathematical machinery of quantum theories. Some general results concerning hidden-variable interpretations of QM such as Gleason's and the Kochen-Specker theorems and the related notions of realism and non-contextuality are carefully discussed. This is done also in relation with the famous Bell (BCHSH) inequality concerning local causality. Written in a didactic style, this book includes many examples and solved exercises. The work is organized as follows. Chapter 1 reviews some elementary facts and properties of quantum systems. Chapter 2 and 3 present the main results of spectral analysis in complex Hilbert spaces. Chapter 4 introduces the point of view of the orthomodular lattices' theory. Quantum theory form this perspective turns out to the probability measure theory on the non-Boolean lattice of elementary observables and Gleason's theorem characterizes all these measures. Chapter 5 deals with some philosophical and interpretative aspects of quantum theory like hidden-variable formulations of QM. The Kochen-Specker theorem and its implications are analyzed also in relation BCHSH inequality, entanglement, realism, locality, and non-contextuality. Chapter 6 focuses on the algebra of observables also in the presence of superselection rules introducing the notion of von Neumann algebra. Chapter 7 offers the idea of (groups of) quantum symmetry, in particular, illustrated in terms of Wigner and Kadison theorems. Chapter 8 deals with the elementary ideas and results of the so called algebraic formulation of quantum theories in terms of both *-algebras and C*-algebras. This book should appeal to a dual readership: on one hand mathematicians that wish to acquire the tools that unlock the physical aspects of quantum theories; on the other physicists eager to solidify their understanding of the mathematical scaffolding of quantum theories.

Quantised Vortices - A Handbook of Topological Excitations (Hardcover): Tapio Simula Quantised Vortices - A Handbook of Topological Excitations (Hardcover)
Tapio Simula
R2,125 Discovery Miles 21 250 Ships in 18 - 22 working days

Vortices comprising swirling motion of matter are observable in classical systems at all scales ranging from atomic size to the scale of galaxies. In quantum mechanical systems, such vortices are robust entities whose behaviours are governed by the strict rules of topology. The physics of quantum vortices is pivotal to basic science of quantum turbulence and high temperature superconductors, and underpins emerging quantum technologies including topological quantum computation. This handbook is aimed at providing a dictionary style portal to the fascinating quantum world of vortices.

Spherical Sampling (Hardcover, 1st ed. 2018): Willi Freeden, M. Zuhair Nashed, Michael Schreiner Spherical Sampling (Hardcover, 1st ed. 2018)
Willi Freeden, M. Zuhair Nashed, Michael Schreiner
R2,313 Discovery Miles 23 130 Ships in 18 - 22 working days

This book presents, in a consistent and unified overview, results and developments in the field of todays spherical sampling, particularly arising in mathematical geosciences. Although the book often refers to original contributions, the authors made them accessible to (graduate) students and scientists not only from mathematics but also from geosciences and geoengineering. Building a library of topics in spherical sampling theory it shows how advances in this theory lead to new discoveries in mathematical, geodetic, geophysical as well as other scientific branches like neuro-medicine. A must-to-read for everybody working in the area of spherical sampling.

Internal and External Stabilization of Linear Systems with Constraints (Hardcover, 2013 ed.): Ali Saberi, Anton A. Stoorvogel,... Internal and External Stabilization of Linear Systems with Constraints (Hardcover, 2013 ed.)
Ali Saberi, Anton A. Stoorvogel, Peddapullaiah Sannuti
R4,190 Discovery Miles 41 900 Ships in 18 - 22 working days

Unifying two decades of research, this book is the first to establish a comprehensive foundation for a systematic analysis and design of linear systems with general state and input constraints. For such systems, which can be used as models for most nonlinear systems, the issues of stability, controller design, additonal constraints, and satisfactory performance are addressed. The book is an excellent reference for practicing engineers, graduate students, and researchers in control systems theory and design. It may also serve as an advanced graduate text for a course or a seminar in nonlinear control systems theory and design in applied mathematics or engineering departments. Minimal prerequisites include a first graduate course in state-space methods as well as a first course in control systems design.

New Computation Methods for Geometrical Optics (Hardcover, 2014 ed.): Psang Dain Lin New Computation Methods for Geometrical Optics (Hardcover, 2014 ed.)
Psang Dain Lin
R3,610 R3,350 Discovery Miles 33 500 Save R260 (7%) Ships in 10 - 15 working days

This book employs homogeneous coordinate notation to compute the first- and second-order derivative matrices of various optical quantities. It will be one of the important mathematical tools for automatic optical design. The traditional geometrical optics is based on raytracing only. It is very difficult, if possible, to compute the first- and second-order derivatives of a ray and optical path length with respect to system variables, since they are recursive functions. Consequently, current commercial software packages use a finite difference approximation methodology to estimate these derivatives for use in optical design and analysis. Furthermore, previous publications of geometrical optics use vector notation, which is comparatively awkward for computations for non-axially symmetrical systems.

Contextual Computing - Models and Applications (Hardcover, 2011 ed.): Robert Porzel Contextual Computing - Models and Applications (Hardcover, 2011 ed.)
Robert Porzel
R2,660 Discovery Miles 26 600 Ships in 18 - 22 working days

Recent advances in the fields of knowledge representation, reasoning and human-computer interaction have paved the way for a novel approach to treating and handling context. The field of research presented in this book addresses the problem of contextual computing in artificial intelligence based on the state of the art in knowledge representation and human-computer interaction. The author puts forward a knowledge-based approach for employing high-level context in order to solve some persistent and challenging problems in the chosen showcase domain of natural language understanding. Specifically, the problems addressed concern the handling of noise due to speech recognition errors, semantic ambiguities, and the notorious problem of underspecification. Consequently the book examines the individual contributions of contextual composing for different types of context. Therefore, contextual information stemming from the domain at hand, prior discourse, and the specific user and real world situation are considered and integrated in a formal model that is applied and evaluated employing different multimodal mobile dialog systems. This book is intended to meet the needs of readers from at least three fields - AI and computer science; computational linguistics; and natural language processing - as well as some computationally oriented linguists, making it a valuable resource for scientists, researchers, lecturers, language processing practitioners and professionals as well as postgraduates and some undergraduates in the aforementioned fields. "The book addresses a problem of great and increasing technical and practical importance - the role of context in natural language processing (NLP). It considers the role of context in three important tasks: Automatic Speech Recognition, Semantic Interpretation, and Pragmatic Interpretation. Overall, the book represents a novel and insightful investigation into the potential of contextual information processing in NLP." Jerome A Feldman, Professor of Electrical Engineering and Computer Science, UC Berkeley, USA http://dm.tzi.de/research/contextual-computing/

Models for Physics of the Very Small and Very Large (Hardcover, 1st ed. 2016): Thomas J. Buckholtz Models for Physics of the Very Small and Very Large (Hardcover, 1st ed. 2016)
Thomas J. Buckholtz
R2,473 Discovery Miles 24 730 Ships in 10 - 15 working days

This monograph tackles three challenges. First, show a mathematics-based meta-model that matches known elementary particles. Second, apply models, based on the meta-model, to match other known physics data. Third, predict future physics data. The math features solutions to isotropic pairs of isotropic quantum harmonic oscillators. This monograph matches some solutions to known elementary particles. Matched properties include spin, types of interactions in which the particles partake, and (for elementary bosons) approximate masses. Other solutions point to possible elementary particles. This monograph applies the models and the extended particle list. Results narrow gaps between physics data and theory. Results pertain to elementary particles, astrophysics, and cosmology. For example, this monograph predicts properties for beyond-the-Standard-Model elementary particles, proposes descriptions of dark matter and dark energy, provides new relationships between known physics constants (including masses of some elementary particles), includes theory that dovetails with the ratio of dark matter to ordinary matter, includes math that dovetails with the number of elementary-fermion generations, suggests forces that govern the rate of expansion of the universe, and suggests additions to and details for the cosmology timeline.

Probing the Early Universe with the CMB Scalar, Vector and Tensor Bispectrum (Hardcover, 2013 ed.): Maresuke Shiraishi Probing the Early Universe with the CMB Scalar, Vector and Tensor Bispectrum (Hardcover, 2013 ed.)
Maresuke Shiraishi
R1,838 Discovery Miles 18 380 Ships in 10 - 15 working days

The non-Gaussianity in the primordial density fluctuations is a key feature to clarify the early Universe and it has been probed with the Cosmic Microwave Background (CMB) bispectrum. In recent years, we have treated the novel-type CMB bispectra, which originate from the vector- and tensor-mode perturbations and include the violation of the rotational or parity invariance. On the basis of our current works, this thesis provides the general formalism for the CMB bispectrum sourced by the non-Gaussianity in the scalar, vector and tensor-mode perturbations. Applying this formalism, we calculate the CMB bispectra from the two scalars and a graviton correlation and primordial magnetic fields, and then outline new constraints on these magnitudes. Furthermore, this formalism can be easily extended to the cases where the rotational or parity invariance is broken. We also compute the CMB bispectra from the scalar-mode non-Gaussianities with a preferred direction and the tensor-mode non-Gaussianities induced by the parity-violating Weyl cubic terms. Here, we show that these bispectra include unique signals, which any symmetry-invariant models can never produce.

Predictive Methods in Percutaneous Absorption (Hardcover, 2015 ed.): Gary P Moss, Darren R Gullick, Simon C Wilkinson Predictive Methods in Percutaneous Absorption (Hardcover, 2015 ed.)
Gary P Moss, Darren R Gullick, Simon C Wilkinson
R4,382 R3,311 Discovery Miles 33 110 Save R1,071 (24%) Ships in 10 - 15 working days

This book sheds new light on the development and use of quantitative models to describe the process of skin permeation. It critically reviews the development of quantitative predictive models of skin absorption and discusses key recommendations for model development. Topics presented include an introduction to skin physiology; the underlying theories of skin absorption; the physical laboratory-based processes used to generate skin absorption data, which is in turn used to construct mathematical models describing the skin permeation process; algorithms of skin permeability including quantitative structure-activity (or permeability) relationships (QSARs or QSPRs); relationships between permeability and molecular properties; the development of formulation-focused approaches to models of skin permeability prediction; the use of artificial membranes, e.g. polydimethylsiloxane as alternatives to mammalian skin; and lastly, the use of novel Machine Learning methods in developing the next generation of predictive skin permeability models. The book will be of interest to all researchers in academia and industry working in pharmaceutical discovery and development, as well as readers from the field of occupational exposure and risk assessment, especially those whose work involves agrochemicals, bulk chemicals and cosmetics.

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