Science is a force for good in the world-at least usually. But sometimes, when obsession gets the better of scientists, they twist a noble pursuit into something sinister. Under this spell, knowledge isn't everything, it's the only thing-no matter the cost. Bestselling author Sam Kean tells the true story of what happens when unfettered ambition pushes otherwise rational men and women to cross the line in the name of science, trampling ethical boundaries and often committing crimes in the process. The Icepick Surgeon masterfully guides the reader across two thousand years of history, beginning with Cleopatra's dark deeds in ancient Egypt. The book reveals the origins of much of modern science in the transatlantic slave trade of the 1700s, as well as Thomas Edison's mercenary support of the electric chair and the warped logic of the spies who infiltrated the Manhattan Project. But the sins of science aren't all safely buried in the past. Many of them, Kean reminds us, still affect us today. We can draw direct lines from the medical abuses of Tuskegee and Nazi Germany to current vaccine hesitancy, and connect icepick lobotomies from the 1950s to the contemporary failings of mental-health care. Kean even takes us into the future, when advanced computers and genetic engineering could unleash whole new ways to do one another wrong. Unflinching, and exhilarating to the last page, The Icepick Surgeon fuses the drama of scientific discovery with the illicit thrill of a true-crime tale. With his trademark wit and precision, Kean shows that, while science has done more good than harm in the world, rogue scientists do exist, and when we sacrifice morals for progress, we often end up with neither.

Race, while drawn from the visual cues of human diversity, is an idea with a measurable past, an identifiable present, and an uncertain future. The concept of race has been at the center of both triumphs and tragedies in American history and has had a profound effect on the human experience. "Race Unmasked" revisits the origins of commonly held beliefs about the scientific nature of racial differences, examines the roots of the modern idea of race, and explains why race continues to generate controversy as a tool of classification even in our genomic age.

Through rigorous historical research, "Race Unmasked" reveals how genetics and related biological disciplines formed and preserved ideas of race and, at times, racism throughout the twentieth century. Surveying the work of some of the twentieth century's most notable scientists, the book tests and then proves the limitations of a racial worldview. This new work is a gripping history of science and scientists that throws the contours of our current and evolving understanding of human diversity into sharp relief.

"When you first view Rose-Lynn Fisher's photographs, you might think you're looking down at the world from an airplane, at dunes, skyscrapers or shorelines. In fact, you're looking at her tears. . . . [There's] poetry in the idea that our emotional terrain bears visual resemblance to the physical world; that our tears can look like the vistas we see out an airplane window. Fisher's images are the only remaining trace of these places, which exist during a moment of intense feeling-and then vanish." -NPR "[A] delicate, intimate book. . . . In The Topography of Tears photographer Rose-Lynn Fisher shows us a place where language strains to express grief, longing, pride, frustration, joy, the confrontation with something beautiful, the confrontation with an onion." -Boston Globe Does a tear shed while chopping onions look different from a tear of happiness? In this powerful collection of images, an award-winning photographer trains her optical microscope and camera on her own tears and those of men, women, and children, released in moments of grief, pain, gratitude, and joy, and captured upon glass slides. These duotone photographs reveal the beauty of recurring patterns in nature and present evocative, crystalline imagery for contemplation. Underscored by poetic captions, they translate the mysterious act of crying into an atlas mapping the structure and magnificence of our interior lives. Rose-Lynn Fisher is an artist and author of the International Photography Award-winning studies Bee and The Topography of Tears. Her photographs are exhibited in galleries, festivals, and museums across the world and have been featured by the Dr. Oz Show, NPR, Smithsonian, Harper's, New Yorker, Time, Wired, Reader's Digest, Discover, Brain Pickings, and elsewhere. She received her BFA from Otis Art Institute and lives in Los Angeles.

Very Short Introductions: Brilliant, Sharp, Inspiring Physiology is the science of life, and sets out to understand how living things work and what makes them distinct from the non-living. It considers how our bodies are supplied with energy, how they maintain their internal parameters, the ways in which we gather and process information, the ways we take action, and the creation of new generations. This Very Short Introduction explores the field of human physiology, considering how the body works, senses, reacts, and defends itself. As Jamie A. Davies shows, human life (and indeed, all life) is sustained by the interplay of a wide variety of physiological mechanisms and principles. He discusses the physiological experiments and research undertaken to understand these processes, and analyses the ethical issues involved. He also considers the evolution of the scientific field itself, showing how enhanced understandings of physiological knowledge can help inform medical research and care. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.

With 2003 being the 100th anniversary of modern aviation, Passenger Behaviour was published at a milestone for the aviation industry. Remarkable achievements in engineering have made air travel highly accessible within the span of a single lifetime. However, when evolutionary barriers are exceeded various penalties are exacted. The most common experienced by air passengers include motion sickness, jetlag and increased arousal and stress at different stages of flight. Air travel also brings us into closer contact with strangers, making our examination and understanding of the social psychology of behaviour within groups (among passengers) especially relevant. This book examines a wide range of topics that help the reader to acquire a psychological understanding of how air travel impacts on human relationships; behaviour as well as physiological functions. Written by leading authorities in their areas, it is intended primarily for those with an interest in passenger behaviour and those who work professionally in commercial aviation. This includes pilots, cabin crew, ground staff, airline and airport managers, aviation psychologists, human factors specialists, aerospace medical/nursing personnel and aircraft designers and manufacturers. As air travel being an integral part of most people's lives, this book will also be of interest to anyone who travels either on a frequent or infrequent basis.

Bio-Architecture studies the natural principles of animal and human constructions from several different perspectives, and presents a great part of the knowledge that gives origin and shape to built form.
Organic architecture offers a design approach arising from natural principles, bringing us back to local history, tradition, and cultural roots to give us built forms which are in harmony with nature. It also shows how architects can take advantage of the resources that contemporary technology has placed within our grasp.
Bio-Architecture is a unique book that studies the natural principles of animal and human constructions from several different perspectives and looks at what gives origin and shape to built form. The text gives an informative, inspiring overview of the drive toward organically informed design both intrinsically and aesthetically using a wide variety of international examples.
Javier Senosiain is an architect and an historian. He has pursued his interest in Organic Architecture across the globe drawing parallels between Buckminster Fuller's Geodesic dome and the spider's web; between Santiago Calatrava's Cathedral of St John in NY and the roots of a tree. Where nature has inspired form, Senosiain has made a career of analyzing and applying the principles he sees in some very creative writing and architecture.
* Beautiful book inspires readers to design with the environment in mind
* Comparative study of the engineering principles in nature and built structures outlines the fundamentals of architectural design
* International examples show how architects use different locations and climates to inform specific biological forms and techniques

Developmental Juvenile Osteology was created as a core reference text to document the development of the entire human skeleton from early embryonic life to adulthood. In the period since its first publication there has been a resurgence of interest in the developing skeleton, and the second edition of Developmental Juvenile Osteology incorporates much of the key literature that has been published in the intervening time. The main core of the text persists by describing each individual component of the human skeleton from its embryological origin through to its final adult form. This systematic approach has been shown to assist the processes of both identification and age estimation and acts as a core source for the basic understanding of normal human skeletal development. In addition to this core, new sections have been added where there have been significant advances in the field.

This fascinating, multi-disciplinary volume weaves together the fields of biology, archaeology, anthropology and history to produce a stimulating and wide-ranging analysis of the biological history of past human populations. Research methods, theoretical approaches and the outcomes of research are all fully explored, and contributions to the book are made by an eminent mix of experts in the afore-mentioned fields.
Comprehensive in its coverage of the subject, chapters include discussions on adaptation and the English demographic regime; British polygyny, warfare and population structure; and a human ecological approach to the interface of history and biology.
A unique interlacing of human biology and history, this book will encourage further reflection and debate and presents a fresh perspective to the subject for students and professionals across all levels in biology, archaeology, anthroplogy and social history.

eBook available with sample pages: 0203217594

The genome's been mapped.
But what does it mean?

Arguably the most significant scientific discovery of the new century, the mapping of the twenty-three pairs of chromosomes that make up the human genome raises almost as many questions as it answers. Questions that will profoundly impact the way we think about disease, about longevity, and about free will. Questions that will affect the rest of your life.

"Genome" offers extraordinary insight into the ramifications of this incredible breakthrough. By picking one newly discovered gene from each pair of chromosomes and telling its story, Matt Ridley recounts the history of our species and its ancestors from the dawn of life to the brink of future medicine. From Huntington's disease to cancer, from the applications of gene therapy to the horrors of eugenics, Matt Ridley probes the scientific, philosophical, and moral issues arising as a result of the mapping of the genome. It will help you understand what this scientific milestone means for you, for your children, and for humankind.

Evolutionary science is critical to an understanding of integrated human biology and is increasingly recognised as a core discipline by medical and public health professionals. Advances in the field of genomics, epigenetics, developmental biology, and epidemiology have led to the growing realisation that incorporating evolutionary thinking is essential for medicine to achieve its full potential. This revised and updated second edition of the first comprehensive textbook of evolutionary medicine explains the principles of evolutionary biology from a medical perspective and focuses on how medicine and public health might utilise evolutionary thinking. It is written to be accessible to a broad range of readers, whether or not they have had formal exposure to evolutionary science. The general structure of the second edition remains unchanged, with the initial six chapters providing a summary of the evolutionary theory relevant to understanding human health and disease, using examples specifically relevant to medicine. The second part of the book describes the application of evolutionary principles to understanding particular aspects of human medicine: in addition to updated chapters on reproduction, metabolism, and behaviour, there is an expanded chapter on our coexistence with micro-organisms and an entirely new chapter on cancer. The two parts are bridged by a chapter that details pathways by which evolutionary processes affect disease risk and symptoms, and how hypotheses in evolutionary medicine can be tested. The final two chapters of the volume are considerably expanded; they illustrate the application of evolutionary biology to medicine and public health, and consider the ethical and societal issues of an evolutionary perspective. A number of new clinical examples and historical illustrations are included. This second edition of a novel and popular textbook provides an updated resource for doctors and other health professionals, medical students and biomedical scientists, as well as anthropologists interested in human health, to gain a better understanding of the evolutionary processes underlying human health and disease.

The diversity of contemporary investigative approaches included in this volume provides an exciting account of our current understanding of brain mechanisms responsible for sensory and perceptual experience in the areas of touch, kinesthesia, and pain.
Postgraduate research students in sensory physiology, neurology, psychology and anatomy, and researchers themselves will find that this volume addresses many of the key issues in our attempts to understand the neural mechanisms that mediate sensory experience arising from the body as a whole, the so-called somatic senses, in particular for touch and pain. The volume provides a record of the occasion of the St Petersburg IUPS symposium, chaired by the editors of this volume, and includes some added recent contributions from other leading international figures in the field. Brought together under the sponsoring banner of the IUPS Commission for Somatosensory Physiology and Pain, these scientists with their different experimental approaches seek collectively to understand the brain mechanisms that underlie our own nature and experience.

This volume dealing with the male body in the iconography of fascism reflects an ambition rather than an achievement. The supremacy of the global fascist superman never became a reality but was certainly an intention. This work explores the use of the image of the male body for this purpose in European, American and Asian fascism of varying degrees and various interpretations, and the differences and similarities involved. Among the similarities isthe fact that sport in all the cases in this volume was at the centre of the induction of the male body (and mind) into martial self-sacrifice. Sport was an important part of fascist socialization. The reasons are not hard to find. Sport develops muscle and muscle is equated with power - literally and metaphorically. War, the essence of fascism, demands physical fitness and sport helps promote this fitness. Competitive sport can help develop attitudes of aggression and aggression is essential in war.

This volume dealing with the male body in the iconography of fascism reflects an ambition rather than an achievement. The supremacy of the global fascist superman never became a reality but was certainly an intention. This work explores the use of the image of the male body for this purpose in European, American and Asian fascism of varying degrees and various interpretations, and the differences and similarities involved. Among the similarities isthe fact that sport in all the cases in this volume was at the centre of the induction of the male body (and mind) into martial self-sacrifice. Sport was an important part of fascist socialization. The reasons are not hard to find. Sport develops muscle and muscle is equated with power - literally and metaphorically. War, the essence of fascism, demands physical fitness and sport helps promote this fitness. Competitive sport can help develop attitudes of aggression and aggression is essential in war.

This text begins with an in-depth overview into the human organism at the molecular, cellular, tissue and organ levels, and develops into a discussion of the objectives and features of organ systems of the evolved human. The book also covers the relationship between the human body and the environment in which it exists including other organisms that co-habitate the environment. Discussions of the nature of other organisms such as various animals, plants, and micro-organisms makes later information about food science, nutrient density in various food sources, and nutraceuticals easier to comprehend.
Advanced Human Nutrition examines human nutrient requirements, the basis for RDA and other recommendations; human nutrition, digestion, and absorption with relation to organs, exocrine and endocrine functions, histology, and absorptive activities; macronutrients and micronutrients; eicosanoid chemistry and function, and more.
The present and future of nutrition research is examined, including everything from the HANES studies to electron microscopy and molecular biology.

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Jerry Stannard assembled a legendary collection of materials on the history of botany from Homer to Linnaeus, and his mastery of the field was acknowledged as incomparable. However, his work was sadly cut short by his death, and so did not result in the ultimate synthesis he envisioned; the present volume, and its companion, Herbs and Herbalism in the Middle Ages and the Renaissance, bring together his important output in articles and studies. In this selection of papers on pharmacy and medical botany, from the classical period to 1500, Stannard combined philological expertise with the scientific perspective of modern pharmacology to measure the descriptive accuracy and therapeutic efficacy of Materia Medica from Hippocrates to the Renaissance. His sources included not only the obvious technical treatises but also works of literature and the traditions of folklore especially in Italy. Three studies of the scholastic botany of Albertus Magnus form the centrepiece of the collection, and the detailed indexes cover both common and scientific names of plants.

Our Human Story is a guide to our fossil relatives, from what may be the earliest hominins such as Sahelanthropus, dating back six to seven million years, through to our own species, Homo sapiens. Over the past 25 years there has been an explosion of species' names in the story of human evolution, due both to new discoveries and to a growing understanding of the diversity that existed in the past. Drawing on this new information, as well as their own considerable expertise and practical experience, Louise Humphrey and Chris Stringer explain in clear and accessible terms what each of the key species represents and how it contributes to our knowledge of human evolution.

It is said that the skull is the only human body part that is as powerful dead as it was when living. Skulls takes the reader on an eerie journey through history seen through the hollow eye sockets of this crown jewel of the human skeleton. The book is made up of a series of short illustrated stories laced with fascinating facts, historical and medical references and compelling anecdotes. The testimonials of thirty-plus skull collectors reveal what is known of - or speculated about - the often gruesome history of the skulls, as well as how they were acquired and what makes them so highly prized.

The transplantation of organs such as the heart, kidney, and lungs is an important means of replacing seriously damaged or diseased body parts. However, a transplanted organ may fail if the recipient's immune system mounts a response to it. Transplant patients are usually prescribed a life-long course of immunosuppressive medication, but these drugs can have adverse effects, including increased risk of infection and cancer. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Medicine provides a current and comprehensive review of the molecular mechanisms behind graft rejection and how they may be overcome. Contributors discuss immunosuppressive drug therapies and tolerance induction strategies, including the use of regulatory T cells, mesenchymal stromal cells, and lymphodepletion. They describe how mouse and non-human primate models have been used to gain insight into the immunobiology of transplantation and to test therapeutic approaches. Clinical considerations, such as donor selection, organ preservation, surgery, and post-operative care, are also covered. This volume includes discussion of the emerging field of regenerative medicine and the bioethical issues surrounding organ transplantation, and provides historical background to the field. It is an essential reference for immunologists, pharmacologists, clinicians, and all who are working to improve this remarkable medical procedure.

This book bridges the gap between a clinician's and material scientists' knowledge by elucidating upon the different biomaterials used in anatomical systems and how those materials react to the human body. It explores both established and future prospective of biomaterial types/designs, and considerations in material selection and synthesis, to guide students from non-clinical background in understanding the relations of material science and the human body.

This handbook presents the most current information on the effects of ionizing radiation on mammalian cells, with emphasis on human tissues. The dose-effect relationship is emphasized in a quantitative manner. The book contains up-to-date data on the late effects of low levels of radiation on humans. It also provides some of the late consequences of radiation therapy detected among cancer survivors.

"Congratulations on the purchase of this exclusive product, tailor-made just for you. It will provide you with years of continuous service." The brain is one of nature's most miraculous but misunderstood creations. In this fascinating user-friendly guide, you will discover all you need to know about what is ceaselessly happening inside your head - from the 38 million billion calculations the brain makes per second, to the complex distribution of memory (there is no central storeroom for information) and why love is an entirely neuronal experience. With wit and style, Marco Magrini cuts through the noise of cerebral misinformation to tell the real story of who you are and, crucially, what you are capable of achieving. N.B. Product comes with a 10-year warranty. T&Cs apply "A fantastically original and clever way to popularise neuroscience." - Professor Gilberto Corbellini, Philosophy of Science, La Sapienza University, Rome "In these pages, Magrini describes beautifully, and often very humorously, the extraordinary harvest of new neuroscientific discoveries shedding light on the most complex and astonishing thing in the universe itself." - Tomaso Poggio, MIT McGovern Institute

A "courageous, compassionate, and rigorous every-person's guide" (Christina Bethell, PhD, Johns Hopkins Bloomberg School of Public Health) that shows the link between Adverse Childhood Experiences (ACEs) and diseases, and how to cope and heal from these emotional traumas. Your biography becomes your biology. The emotional trauma we suffer as children not only shapes our emotional lives as adults, but it also affects our physical health, longevity, and overall well-being. Scientists now know on a bio-chemical level exactly how parents' chronic fights, divorce, death in the family, being bullied or hazed, and growing up with a hypercritical, alcoholic, or mentally ill parent can leave permanent, physical "fingerprints" on our brains. When children encounter sudden or chronic adversity, stress hormones cause powerful changes in the body, altering the body's chemistry. The developing immune system and brain react to this chemical barrage by permanently resetting children's stress response to "high," which in turn can have a devastating impact on their mental and physical health as they grow up. Donna Jackson Nakazawa shares stories from people who have recognized and overcome their adverse experiences, shows why some children are more immune to stress than others, and explains why women are at particular risk. "Groundbreaking" (Tara Brach, PhD, author of Radical Acceptance) in its research, inspiring in its clarity, Childhood Disrupted explains how you can reset your biology-and help your loved ones find ways to heal. "A truly important gift of understanding-illuminates the heartbreaking costs of childhood trauma and like good medicine offers the promising science of healing and prevention" (Jack Kornfield, author of A Path With Heart).

John Dupre explores recent revolutionary developments in biology and considers their relevance for our understanding of human nature and human society. Epigenetics and related areas of molecular biology have eroded the exceptional status of the gene and presented the genome as fully interactive with the rest of the cell. Developmental systems theory provides a space for a vision of evolution that takes full account of the fundamental importance of developmental processes. Dupre shows the importance of microbiology for a proper understanding of the living world, and reveals how it subverts such basic biological assumptions as the organisation of biological kinds on a branching tree of life, and the simple traditional conception of the biological organism.
These topics are considered in the context of a view of science as realistically grounded in the natural order, but at the same time as pluralistic and inextricably integrated within a social and normative context. The volume includes a section that recapitulates and expands some of the author's general views on science; a section addressing a range of topics in biology, including the significance of genomics, the nature of the organism and the current status of evolutionary theory; and a section exploring some implications of contemporary biology for humans, for example on the reality or unreality of human races, and the plasticity of human nature.

Building on the success of the second edition, this truly accessible textbook comprehensively covers the 2008 AS and A2 level Human Biology specifications for all the main UK exam boards.The book also has a companion website which is free to book users providing extra resources. Written by authors with many years' experience of teaching, examining and writing, this is an ideal resource for class or independent study. The book includes the following features: How Science Works feature boxes focus on this key element of the new specifications. Stretch and Challenge boxes challenge more able students, enabling them to achieve the highest grades. Science in Context boxes encourage students to relate their learning to the world around them. Summaries at the end of every chapter help students with revision. Test Yourself questions throughout the text enable students to monitor their own progress in preparation for their exams. Remember This boxes highlight the key facts. The website provides the following additional resources: Practice questions (and answers) allow students to test their understanding of the material just covered. How Science Works assignments allow students to prepare for the How Science Works element of the new AS and A2 Human Biology exams.

Researchers have long had an interest in dental morphology as a genetic proxy to reconstruct population history. Much interest was fostered by the use of standard plaques and associated descriptions that comprise the Arizona State University Dental Anthropology System, developed by Christy G. Turner, II and students. This system has served as the foundation for hundreds of anthropological studies for over 30 years. In recognition of that success, this volume brings together some of the world's leading dental morphologists to expand upon the concepts and methods presented in the popular The Anthropology of Modern Human Teeth (Cambridge, 1997), leading the reader from method to applied research. After a preparatory section on the current knowledge of heritability and gene expression, a series of case studies demonstrate the utility of dental morphological study in both fossil and more recent populations (and individuals), from local to global scales.