In this masterwork, Russell H. Tuttle synthesizes a vast research literature in primate evolution and behavior to explain how apes and humans evolved in relation to one another, and why humans became a bipedal, tool-making, culture-inventing species distinct from other hominoids. Along the way, he refutes the influential theory that men are essentially killer apes--sophisticated but instinctively aggressive and destructive beings. Situating humans in a broad context, Tuttle musters convincing evidence from morphology and recent fossil discoveries to reveal what early primates ate, where they slept, how they learned to walk upright, how brain and hand anatomy evolved simultaneously, and what else happened evolutionarily to cause humans to diverge from their closest relatives. Despite our genomic similarities with bonobos, chimpanzees, and gorillas, humans are unique among primates in occupying a symbolic niche of values and beliefs based on symbolically mediated cognitive processes. Although apes exhibit behaviors that strongly suggest they can think, salient elements of human culture--speech, mating proscriptions, kinship structures, and moral codes--are symbolic systems that are not manifest in ape niches. This encyclopedic volume is both a milestone in primatological research and a critique of what is known and yet to be discovered about human and ape potential.

As one of the world's leading brain surgeons, Dr Jandial is the last hope for many patients who have extreme forms of cancer - patients who can't be saved, but deserve more time. Life on a Knife's Edge is his account of the resilience, courage and belief he has witnessed in his patients, and the lessons he has learned from them. Both an unflinching account of extreme surgeries and a profound, moving and introspective memoir, this book reveals the depths of a surgeon's psyche who is pushed to his limits, day in, day out. From keeping a gun victim's heart pumping with his own hand, to saving a woman from paralysis and performing brain surgery while time is running out on a haemorrhaging patient, we see how making life and death decisions and facing unimaginable pressure has shaped one man's life. Now, he shares the many truths about human nature that he has learned along the way: from how we deal with trauma, loss and threat to our innate belief and sense of self. From a life spent balancing on the line between life and death, above all else he reveals what it really means to survive.

The Laboratory Manual provides an emphasis on critical thinking and includes Safety Guidelines, Objectives, A List of Materials Needed, Topic Introduction, Activities with embedded questions, and Critical Thinking Questions.

A highly entertaining book debunking the many myths about the human body. Everything You Know About the Human Body is Wrong debunks the scientific myths we all take for granted. Written by author Matt Brown in his trademark humourous style, this book takes you through all the facts we thought true, from bodily blunders, medical mis-quotes and curious cures. Does giving kids sugar make them go hyper-active? Not at all - there is no proven link! Is there such a thing as being 'double-jointed'? And is it dangerous to swim after eating? Covering everything from pseudoscience to recent research, Everything You Know About the Human Body is Wrong shatters a range of illusions we have accepted unquestioningly since childhood and demystifies this most puzzling of subjects.

Metal ions are poorly known whereas they sometimes play a role more significant than vitamins. Moreover they control many diseases, such as the zinc salts in dermatology. Another example is the recent discovery of platinum co-ordination compounds' anti-tumor activity (cisplatine). There is a growing volume of literature too. The chemistry of metal ions has provided new insights into DNA, proteins and membrane chemistry, as well as the physiopathology of diseases. This book contains the proceedings of 2nd International Symposium on Metal Ions in Biology and Medicine, Athens, May 1992.

'A work of exhilarating scope and relevance ... What a rare and powerful experience to feel a book in your very body' Naomi Klein 'Health is not something we can attain as individuals, for ourselves, hermetically sealed off from the world around us. An injury to one is an injury to all.' Our bodies, societies and planet are inflamed. In this boldly original book, renowned political economist Raj Patel teams up with physician Rupa Marya to illuminate the hidden relationships between human health and the profound injustices of our political and economic systems. In doing so, they offer a radical new cure: the deep medicine of decolonization. Journeying through the human body - our digestive, endocrine, circulatory, respiratory, reproductive, immune, and nervous systems - Marya and Patel show how inflammation is connected not just to the food that we eat, the air that we breathe and access to healthcare, but is also linked to the traumatic events we experience and the very model of health that doctors practice: one which takes things apart, rather than seeking to bring ideas and lived experiences together. Combining the latest scholarship on globalization and biology with the stories of patients in marginalized communities and the wisdom of Indigenous groups, Inflamed points the way toward a medicine that heals what has been divided and has the potential to transform not only our bodies but the world.

Knowledge of chimpanzees in the wild has expanded dramatically in recent years. This comprehensive volume, edited by Martin Muller, Richard Wrangham, and David Pilbeam, brings together scientists who are leading a revolution to discover and explain what is unique about humans, by studying their closest living relatives. Their observations and conclusions have the potential to transform our understanding of human evolution. Chimpanzees offer scientists an unmatched view of what distinguishes humanity from its apelike ancestors. Based on evidence from the hominin fossil record and extensive morphological, developmental, and genetic data, Chimpanzees and Human Evolution makes the case that the last common ancestor of chimpanzees and humans was chimpanzee-like. It most likely lived in African rainforests around eight million years ago, eating fruit and walking on its knuckles. Readers will learn why chimpanzees are a better model for the last common ancestor than bonobos, gorillas, or orangutans. A thorough chapter-by-chapter analysis reveals which key traits we share with chimpanzees and which appear to be distinctive to Homo sapiens, and shows how understanding chimpanzees helps us account for the evolution of human uniqueness. Traits surveyed include social behaviors and structures, mating systems, diet, hunting practices, tool use, culture, cognition, and communication. Edited by three of primatology's most renowned experts, with contributions from 32 scholars drawing on decades of field research, Chimpanzees and Human Evolution provides readers with detailed up-to-date information on what we can infer about our chimpanzee-like ancestors and points the way forward for the next generation of discoveries.

"A dazzling journey across the sciences and humanities in search of deep laws to unite them." --The Wall Street Journal

One of our greatest living scientists--and the winner of two Pulitzer Prizes for On Human Nature and The Ants--gives us a work of visionary importance that may be the crowning achievement of his career. In Consilience  (a word that originally meant "jumping together"), Edward O. Wilson renews the Enlightenment's search for a unified theory of knowledge in disciplines that range from physics to biology, the social sciences and the humanities.

Using the natural sciences as his model, Wilson forges dramatic links between fields. He explores the chemistry of the mind and the genetic bases of culture. He postulates the biological principles underlying works of art from cave-drawings to Lolita. Presenting the latest findings in prose of wonderful clarity and oratorical eloquence, and synthesizing it into a dazzling whole, Consilience is science in the path-clearing traditions of Newton, Einstein, and Richard Feynman.

As the profession of clinical exercise physiology continues to evolve, there is one cornerstone text that evolves along with it. Clinical Exercise Physiology, Fourth Edition With Web Resource, has been a mainstay in the field since its inception in 2003, and the revisions and additions to this latest rendition reinforce its elite status. As the most comprehensive resource available, Clinical Exercise Physiology, Fourth Edition, provides greater coverage and depth of diseases than is typically found in most clinical exercise physiology textbooks. It thoroughly examines the effects of exercise on chronic disease and then investigates 24 chronic conditions, covering the scope of each disease as well as the pathophysiology, medications, and clinical applications. It also examines clinical considerations and exercise prescriptions for four special populations. This fourth edition reflects the latest American College of Sports Medicine (ACSM) standards and guidelines, making it an ideal resource for candidates preparing for ACSM Clinical Exercise Physiologist certification. In addition to updated content that aligns with current science and evidence-based practice guidelines, the fourth edition also incorporates the following: * A closer and more up-to-date look at the state of the profession * A new web resource featuring case studies that depict real-life scenarios * A new chapter on Parkinson's disease * Enhanced coverage of exercise testing and exercise prescription, in separate chapters to delve deeper into each of those topics * An expanded chapter on end-stage renal disease, to more broadly cover chronic kidney disease * Significant revisions to chapters on metabolic syndrome, diabetes, and heart failure The online case studies are written in the form of SOAP (Subjective, Objective, Assessment, Plan) notes, reflecting common medical chart documentation, to help readers experience realistic examples. The text also offers Practical Application sidebars in each chapter; some of these sidebars focus on exercise prescription, and other Practical Application sidebars review the relevant literature related to physiological adaptations to exercise training. To aid in course preparation, instructors are provided a test package, chapter quizzes, and a presentation package plus image bank. Clinical Exercise Physiology, Fourth Edition, offers a contemporary review of the variety of diseases and conditions that students and professionals may encounter in the field. New and veteran clinical exercise physiologists alike, as well as those preparing for ACSM certification exams, will appreciate the in-depth coverage of the clinical populations that benefit from physical activity and exercise.

Biomedical Scientists are the foundation of modern healthcare, from cancer screening to diagnosing HIV, from blood transfusion for surgery to food poisoning and infection control. Without Biomedical Scientists, the diagnosis of disease, the evaluation of the effectiveness of treatment, and research into the causes and cures of disease would not be possible. The Fundamentals of Biomedical Science series has been written to reflect the challenges of practicing Biomedical Science today. It draws together essential basic science with insights into laboratory practice to show how an understanding of the biology of disease is coupled to the analytical approaches that lead to diagnosis. Assuming only a minimum of prior knowledge, the series reviews the full range of disciplines to which a Biomedical Scientist may be exposed - from microbiology to cytopathology to transfusion science. Haematology provides a broad-ranging overview of the study of blood, the dynamic fluid that interfaces with all organs and tissues to meditate essential transport and regulatory functions. Written with the needs of the Biomedical Scientist centre-stage, it provides a firm grounding in the physiology of blood, and the key pathophysiological states that can arise. It demonstrates throughout how an understanding of physiology underpins the key investigations carried out by a Biomedical Scientist to forge a clear link between science and practice. The third edition has been thoroughly revised to remain up to date with the latest scientific research, with new sections and case studies added to support your learning. The online resources to accompany Haematology have also been updated and include multiple choice questions to test understanding, a Journal Club which provides discussion questions for relevant research papers, and answers to case study and self-check questions. Students and lecturers will also have access to the FBMS series online resources, which feature video interviews with practicing biomedical scientists and 'in the lab' footage showing biomedical techniques. Also available as an ebook with functionality, navigation features, and links that offer extra learning support.

A fundamental and groundbreaking reassessment of how we view and manage cancer When we think of the forces driving cancer, we don't necessarily think of evolution. But evolution and cancer are closely linked because the historical processes that created life also created cancer. The Cheating Cell delves into this extraordinary relationship, and shows that by understanding cancer's evolutionary origins, researchers can come up with more effective, revolutionary treatments. Athena Aktipis goes back billions of years to explore when unicellular forms became multicellular organisms. Within these bodies of cooperating cells, cheating ones arose, overusing resources and replicating out of control, giving rise to cancer. Aktipis illustrates how evolution has paved the way for cancer's ubiquity, and why it will exist as long as multicellular life does. Even so, she argues, this doesn't mean we should give up on treating cancer-in fact, evolutionary approaches offer new and promising options for the disease's prevention and treatments that aim at long-term management rather than simple eradication. Looking across species-from sponges and cacti to dogs and elephants-we are discovering new mechanisms of tumor suppression and the many ways that multicellular life-forms have evolved to keep cancer under control. By accepting that cancer is a part of our biological past, present, and future-and that we cannot win a war against evolution-treatments can become smarter, more strategic, and more humane. Unifying the latest research from biology, ecology, medicine, and social science, The Cheating Cell challenges us to rethink cancer's fundamental nature and our relationship to it.

'The series Youth: Perspectives and Practice provides a distinctive and rare combination of expert commentary, new research, original theorising and critical reflection on how we should understand youth and work with young people. These books deserve a wide readership ... the way they are written and organised will make them particularly appealing to students' - Professor Robert MacDonald, University of Teesside Inventing Adulthoods offers a ground-breaking new perspective on young peoples' experiences of growing up at the turn of the 21st century, arguing that a biographical approach is vital to understanding the holistic and dynamic character of their lives. Based on a study of a diverse group of young people over a 10 year period, the book explores high profile policy issues: education, employment, drugs, cultures of violence and well-being. It also considers the significance of those things that mean most to young people themselves: mobility, home, belonging, intimacy and social life. The book is written in a lively and engaging style and, through case studies and interviews, examines: " the impact that social factors such as gender, class, sexuality, religion, disability and family have on life opportunities; and " connections between young people's lives, social policy frameworks and practice applications. Inventing Adulthoods is an invaluable resource to anyone interested in the lives of young people. Thought-provoking yet accessible, this book is ideal for students in youth studies and education, as it is for youth workers, social workers and other practitioners. Inventing Adulthoods is the set book for the Open University course Youth: Perspectives and Practice (KE308). Sheila Henderson is a Visiting Fellow at London South Bank University. Janet Holland is Professor of Social Research and Co-director of the Families and Social Capital ESRC Research Group at London South Bank University. Sheena McGrellis is a Senior Research Fellow in the Families Group, but is based at University of Ulster. Sue Sharpe is a Visiting Fellow at London South Bank University. Rachel Thomson is Professor of Social Research in the Faculty of Health and Social Care at The Open University.

Essential Computational Modeling for the Human Body presents key contributions selected from the volume in the Handbook of Numerical Analysis: Computational Modeling for the Human Body Vol. 12 (2005).

Computational (Mathematical) Modeling is used by scientists and researchers with various applications in chemical, biological, behavioral, environmental sciences, etc. This guide presents essential research techniques for analysis and essential concrete examples of computational models, while supplying a wide range of commonly used methods and applications, followed by various numerical simulations.

Provides various viewpoints of methods and applications are available for researchers to chose and experiment with; Numerical analysis and open problems useful for experimentation; Computational Models useful for surgery simulations;

"Congratulations on the purchase of this exclusive product, tailor-made just for you. It will provide you with years of continuous service." The brain is one of nature's most miraculous but misunderstood creations. In this fascinating user-friendly guide, you will discover all you need to know about what is ceaselessly happening inside your head - from the 38 million billion calculations the brain makes per second, to the complex distribution of memory (there is no central storeroom for information) and why love is an entirely neuronal experience. With wit and style, Marco Magrini cuts through the noise of cerebral misinformation to tell the real story of who you are and, crucially, what you are capable of achieving. N.B. Product comes with a 10-year warranty. T&Cs apply "A fantastically original and clever way to popularise neuroscience." - Professor Gilberto Corbellini, Philosophy of Science, La Sapienza University, Rome "In these pages, Magrini describes beautifully, and often very humorously, the extraordinary harvest of new neuroscientific discoveries shedding light on the most complex and astonishing thing in the universe itself." - Tomaso Poggio, MIT McGovern Institute

What is epidemiology? What are the causes of a new disease? How can pandemics be prevented? Epidemiology is the study of the changing patterns of disease and its main aim is to improve the health of populations. It's a vital field, central to the health of society, to the identification of causes of disease, and to their management and prevention. Epidemiology has had an impact on many areas of medicine; from discovering the relationship between tobacco smoking and lung cancer, to the origin and spread of new epidemics. However, it is often poorly understood, largely due to misrepresentations in the media. In this Very Short Introduction Rodolfo Saracci dispels some of the myths surrounding the study of epidemiology. He provides a general explanation of the principles behind clinical trials, and explains the nature of basic statistics concerning disease. He also looks at the ethical and political issues related to obtaining and using information concerning patients, and trials involving placebos. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.

In The Story of the Human Body, Daniel Lieberman, Professor of human evolutionary biology at Harvard, shows how we need to change our world to fit our hunter-gatherer bodies This ground-breaking book of popular science explores how the way we use our bodies is all wrong. From an evolutionary perspective, if normal is defined as what most people have done for millions of years, then it's normal to walk and run 9 -15 kilometres a day to hunt and gather fresh food which is high in fibre, low in sugar, and barely processed. It's also normal to spend much of your time nursing, napping, making stone tools, and gossiping with a small band of people. Our 21st-century lifestyles, argues Daniel Lieberman, are out of synch with our stone-age bodies. Never have we been so healthy and long-lived - but never, too, have we been so prone to a slew of problems that were, until recently, rare or unknown, from asthma, to diabetes, to - scariest of all - overpopulation. The Story of the Human Body asks how our bodies got to be the way they are, and considers how that evolutionary history - both ancient and recent - can help us evaluate how we use our bodies. How is the present-day state of the human body related to the past? And what is the human body's future? 'Monumental. The Story of the Human Body, by one of our leading experts, takes us on an epic voyage' - Neil Shubin, author of Your Inner Fish 'Riveting, enlightening, and more than a little frightening' - Christopher McDougall, author of Born to Run Daniel Lieberman is the Chair of the Department of Human Evolutionary Biology at Harvard and a leader in the field. He has written nearly 100 articles, many appearing in the journals Nature and Science, and his cover story on barefoot running in Nature was picked up by major media the world over. His research and discoveries have been highlighted in newspapers and magazines, including The New York Times, Boston Globe, Discover, and National Geographic.

An inquisitive, expansive and fascinating exploration of humans as creatures of our own making Other species adapt to their environments; we alone create ours. Over generations, we have remade the world to suit ourselves - using improved knowledge and technology to confront the traditional scourges - and for the most part we enjoy prosperity beyond the dreams of our ancestors. What's more, in changing our world, we have also reshaped the human phenotype - the interaction between genes and environment that moulds our bodies and minds. The results can be seen in the streets of our post-industrial cities. We grow taller and heavier than before, and live longer. We think and behave differently, and die from once rare diseases. Our experiences of life have been transformed, and in turn so have our societies. Weaving together biology, social anthropology, epidemiology and history, Edwin Gale examines the shifting physical and mental dimensions of our lives, from ageing to illness, food production to reproduction, designer bodies to IQ tests, and asks: are we a self-domesticated species?

Acclaimed science journalist Christie Aschwanden takes readers on an entertaining and enlightening tour through the latest science on sports and fitness recovery. She investigates claims about sports drinks, chocolate milk, and "recovery" beer; examines the latest recovery trends; and even tests some for herself, including cryotherapy, foam rolling, and Tom Brady-endorsed infrared pajamas. Good to Go seeks an answer to the question: Do any of these things actually help the body recover and achieve peak performance?

The papers and reviews in the present volume are in part regular contributions submitted for publication in Biological Trace Element Research, and in part invited papers from participants of the International Symposium "Present Status and Perspectives of Sele- nium in Biology and Medicine," held on May 2 and 3, 1987, at the Eu- ropean Academy, Nonnweiler /Trier, FRG. The Symposium focused on ecological and biomedical aspects of selenium with emphasis on the manifestations of selenium deficiency in different countries, the distribution of selenium in human organs and body fliuds, the roles of selenium in health and disease, its anti carcinogenic action, effects of supplementation, and therapeutic applications. Organized jointly by the International Association of Bioinor- ganic Scientists and BioSynopsia, a Nonprofit Subsidiary of the Tech- nology Center, Stuttgart, the scientific board consisted of Professors W. Hartfiel, Bonn, FRG, G. N. Schrauzer, La Jolla, CA, USA, and H. Zumkley, Muenster, FRG.

This book is a provocative and invigorating real-time exploration of the future of human evolution by two of the world's leading interdisciplinary ecologists - Michael Charles Tobias and Jane Gray Morrison. Steeped in a rich multitude of the sciences and humanities, the book enshrines an elegant narrative that is highly empathetic, personal, scientifically wide-ranging and original. It focuses on the geo-positioning of the human Self and its corresponding species. The book's overarching viewpoints and poignant through-story examine and powerfully challenge concepts associated historically with assertions of human superiority over all other life forms. Ultimately, The Hypothetical Species: Variables of Human Evolution is a deeply considered treatise on the ecological and psychological state of humanity and her options - both within, and outside the rubrics of evolutionary research - for survival. This important work is beautifully presented with nearly 200 diverse illustrations, and is introduced with a foreword by famed paleobiologist, Dr. Melanie DeVore.

The first and still the only book of its kind, this volume offers a concise introduction to human genetic linkage analysis and gene mapping. Jurg Ott provides mathematical and statistical foundations of linkage analysis for researchers and practitioners, as well as practical comments on available computer programs and websites. Each chapter ends with a set of problems, whose solutions are found at the end of the book.

New to this edition is a chapter on complex traits, such as diabetes, some cancers, and psychiatric conditions. Also new is an overview of nonparametric approaches to linkage and association analysis. A chapter on two-locus inheritance introduces the reader to many of the intricate aspects of complex traits. Although the book's primary audience is in the field of genetics, physicians and others without sophisticated training in genetics can understand and apply the principles and techniques discussed.