As in other volumes in the series, this newest volume conveys up-to-date knowledge in a clear and straightforward manner. It begins with a survey of the neurobiological functions of the brain, with the emphasis on Parkinson's disease. This is followed by a presentation of the role of dopamine in the regulation of human anterior pituitary function. The final two chapters concentrate on the dopamine receptors: first, the binding sites are characterized and the biochemical and physiological consequences of dopamine-receptor stimulation are discussed and, finally, there is a report on the topology of a dopamine-receptor model that can account comprehensively for agonists and antagonists.

The biological action of radiation undoubtedly constitutes an issue of actual con cern, particularly after incidences like those in Harrisburg or Chernobyl. These considerations, however, were not the reason for writing this book although it is hoped that it will also be helpful in this respect. The interaction of radiation with biological systems is such an interesting research objective that to my mind no special justification is needed to pursue these problems. The combination of physics, chemistry and biology presents on one hand a fascinating challenge to the student, on the other, it may lead to insights which are not possible if the dif ferent subjects remain clearly separated. Special problems of radiation biology have quite often led to new approaches in physics (or vice versa), a recent example is "microdosimetry" (chapter 4). Biological radiation a9tion comprises all levels of biological organization. It starts with the absorption in essential atoms and molecules and ends with the development of cancer and genetic hazards to future generations. The structure of the book reflects this. Beginning with physical and chemical fundamentals, it then turns to a description of chemical and subcellular systems. Cellular effects form a large part since they are the basis for understanding all further responses. Reactions of the whole organism, concentrating on mammals and especially humans, are subsequently treated. The book concludes with a short discussion of problems in radiation protection and the application of radiation in medical therapy. These last points are necessarily short and somewhat superficial."

A clear and straightforward explanation of genetics in this new edition of the popular 101 series. Our genetic makeup determines so much about who we are, and what we pass on to our children-from eye color, to height, to health, and even our longevity. Genetics 101 breaks down the science of how genes are inherited and passed from parents to offspring, what DNA is and how it works, how your DNA affects your health, and how you can use your personal genomics to find out more about who you are and where you come from. Whether you're looking for a better scientific understanding of genetics, or looking into your own DNA, Genetics 101 is your go-to source to discover more about both yourself and your ancestry.

Adopts an "issues approach" to teaching introductory biology Up-to-date on relevant topics like climate change, CRISPR, new hominids, and new cancer therapies Suitable for both a majors and non-majors course More succinct for ease in teaching and more affordable for students A large suite of student resources, such as questions to enable self-testing, simulations of key processes to aid learning, web links to encourage further reading Instructor resources to use in teaching, such as PowerPoint slides with figures from the book, activity and assignment ideas, and comprehensive lesson plans

'Endlessly fascinating and full of surprises. Easily one of my books of the year' BILL BRYSON The myth-busting science behind our modern attitudes to exercise: what our bodies really need, why it matters, and its effects on health and wellbeing. In industrialized nations, our sedentary lifestyles have contributed to skyrocketing rates of obesity and diseases like diabetes. A key remedy, we are told, is exercise - voluntary physical activity for the sake of health. However, most of us struggle to stay fit, and our attitudes to exercise are plagued by misconceptions, finger-pointing and anxiety. But, as Daniel Lieberman shows in Exercised, the first book of its kind by a leading scientific expert, we never evolved to exercise. We are hardwired for moderate exertion throughout each day, not triathlons or treadmills. Drawing on over a decade of high-level scientific research and eye-opening insights from evolutionary biology and anthropology, Lieberman explains precisely how exercise can promote health; debunks persistent myths about sitting, speed, strength and endurance; and points the way towards more enjoyable and physically active living in the modern world. 'Myth-busting, illuminating, brilliant - Lieberman will completely change the way you think about your body' Professor ALICE ROBERTS, presenter of Our Incredible Human Journey

The papers and reviews in the present volume are in part regular contributions submitted for publication in Biological Trace Element Research, and in part invited papers from participants of the International Symposium "Present Status and Perspectives of Sele- nium in Biology and Medicine," held on May 2 and 3, 1987, at the Eu- ropean Academy, Nonnweiler /Trier, FRG. The Symposium focused on ecological and biomedical aspects of selenium with emphasis on the manifestations of selenium deficiency in different countries, the distribution of selenium in human organs and body fliuds, the roles of selenium in health and disease, its anti carcinogenic action, effects of supplementation, and therapeutic applications. Organized jointly by the International Association of Bioinor- ganic Scientists and BioSynopsia, a Nonprofit Subsidiary of the Tech- nology Center, Stuttgart, the scientific board consisted of Professors W. Hartfiel, Bonn, FRG, G. N. Schrauzer, La Jolla, CA, USA, and H. Zumkley, Muenster, FRG.

The latest edition of Robert Arking's seminal text on the biology of aging takes on an extended title, since the field of gerontology has advanced to a point at which it is possible to separate the topic into two implicit subsets, longevity and aging. This multi-faceted description of the biology of aging guides the reader through increasingly interesting answers to seven fundamental questions: What is aging? Why do we age? What mechanisms support extended longevity? What determines the onset of senescence? What is the mechanistic basis of senescence? Why do humans live so long? And lastly, what pro-longevity societal interventions are needed? Inevitably, humans will age but there is no reason why we must suffer from age-related diseases. Aging and longevity are dependent on both genes and social environment. Our biology does not forbid the modulation of aging. What we really want to know is not so much about the biology of aging - which is basically a degenerative process - but rather about biological processes underlying the long term maintenance of our health. New chapters incorporate the latest developments in the field of gerontology. Research done since the previous edition was published has given us insight into how we may stay healthier longer.

From an award-winning medic and scientist, the game-changing case that genetic females have greater resilience, immunity, endurance and more, compared with males 'A powerful antidote to the myth of a "weaker sex"' Gina Rippon, author of The Gendered Brain From birth, genetic females are better at fighting viruses, infections and cancer. They do better at surviving epidemics and famines. They live longer, and even see the world in a wider variety of colours. These are the facts; they are simply stronger than men at every stage of life. Why? And why are we taught the opposite? Drawing on his wide-ranging experience and cutting-edge research as a medic, geneticist and specialist in rare diseases, Dr Sharon Moalem set out to understand why women are consistently more likely than men to thrive. The answer, he reveals, lies in our genetics: the female's double XX chromosomes offer a powerful survival advantage. Moalem explains why genetic females outperform males when it comes to immunity, resilience, stamina and much more. And he calls for a long-overdue reconsideration of our male-centric, one-size-fits-all view of the body and of how we prescribe medications - a view that still frames women through the lens of men. Revolutionary, captivating and utterly persuasive, The Better Half will make you see women, men and the survival of our species anew.

like other collections of papers related to a single topic, this volume arose out of problem-sharing and problem-solving discussions among some of the authors. The two principal recurring issues were (1) the difficulties in translating anthropo logical knowledge so that our students could use it and (2) the difficulties of bringing existing medical anthropology literature to bear on this task. As we talked to other anthropologists teaching in other parts of the country and in various health-related schools, we recognized that our problems were similar. Similarities in our solutions led the Editors to believe that publication of our teaching experi ences and research relevant to teaching would help others and might begin the process of generating principles leading to a more coherent approach. Our colleagues supported this idea and agreed to contribute. What we agreed to write about was 'Clinically Applied Anthropology'. Much of what we were doing and certainly much of the relevant literature was applied anthropology. And our target group was composed-mostly of clinicians. The utility of the term became apparent after 1979 when another set of anthropologists began to discuss 'ainical Anthropology'. They too recognized the range of novel be haviors available to anthropologists in the health science arena and chose to focus on the clinical use of anthropology. We see this as an important endeavor, but very different from what we are proposing."

Biomedical Scientists are the foundation of modern healthcare, from cancer screening to diagnosing HIV, from blood transfusion for surgery to food poisoning and infection control. Without Biomedical Scientists, the diagnosis of disease, the evaluation of the effectiveness of treatment, and research into the causes and cures of disease would not be possible. The Fundamentals of Biomedical Science series has been written to reflect the challenges of practicing Biomedical Science today. It draws together essential basic science with insights into laboratory practice to show how an understanding of the biology of disease is coupled to the analytical approaches that lead to diagnosis. Assuming only a minimum of prior knowledge, the series reviews the full range of disciplines to which a Biomedical Scientist may be exposed - from microbiology to cytopathology to transfusion science. Haematology provides a broad-ranging overview of the study of blood, the dynamic fluid that interfaces with all organs and tissues to meditate essential transport and regulatory functions. Written with the needs of the Biomedical Scientist centre-stage, it provides a firm grounding in the physiology of blood, and the key pathophysiological states that can arise. It demonstrates throughout how an understanding of physiology underpins the key investigations carried out by a Biomedical Scientist to forge a clear link between science and practice. The third edition has been thoroughly revised to remain up to date with the latest scientific research, with new sections and case studies added to support your learning. The online resources to accompany Haematology have also been updated and include multiple choice questions to test understanding, a Journal Club which provides discussion questions for relevant research papers, and answers to case study and self-check questions. Students and lecturers will also have access to the FBMS series online resources, which feature video interviews with practicing biomedical scientists and 'in the lab' footage showing biomedical techniques. Also available as an ebook with functionality, navigation features, and links that offer extra learning support.

The imaging aspects of radiography have undergone con many sources and was in general freely given when requested siderable change in the last few years and as a teacher of and this is gratefully acknowledged. In particular I would radiography for many years I have often noticed the lack of a like to express my sincere thanks for help and information to comprehensive reference book for students. This book is an Mr J. Day of DuPont (UK) Ltd. particularly for the infor attempt to correct that situation and I hope this text will be mation and illustrations in the chapter on automated film of value not only to student radiographers but also prac handling; Mr D. Harper and Mr R. Black of Kodak Ltd.; tising radiographers as well. Fujimex Ltd.; CEA of Sweden; 3M (UK) Ltd.; Wardray Much of the information is based on personal experiment Products Ltd.; D. A. Pitman Ltd.; Agfa-Gevaert; PSR Ltd. and the knowledge gained of students' difficulties in studying for their help with information on silver recovery, and this subject. I have attempted to gather together in one book Radiatron Ltd. for their help with safelighting. All were most all the information required to understand the fundamentals helpful in my many requests for information. of the subject both for examination and for practice. Some To Mrs A. Dalton and Mrs P."

A rich and abundant literature has developed during the last half century dealing with mechanical aspects of the eye, mainly from clinical and, experimental points of view. For the most part, workers have attempted to shed light on the complex set of conditions known by the general term glaucoma. These conditions are characterised by an increase in intraocular pressure sufficient to cause de generation of the optic disc and concomitant defects in the visual field, which, if not controlled, lead to inevitable permanent blindness. In the United States alone, an estimated 50,000 persons are blind as a result of glaucoma, which strikes about 2% of the population over 40 years of age (Vaughan and Asbury, 1974). An understanding of the underlying mechanisms of glaucoma is hindered by the fact that elevated intraocular pressure, like a runny nose, is but a symptom which may have a variety of causes. Only by turning to the initial pathology can one hope to understand this important class of medical problems."

From New York Times bestselling author Sam Kean comes more incredible stories of science, history, language, and music, as told by our own DNA.
In "The Disappearing Spoon," bestselling author Sam Kean unlocked the mysteries of the periodic table. In THE VIOLINIST'S THUMB, he explores the wonders of the magical building block of life: DNA.
There are genes to explain crazy cat ladies, why other people have no fingerprints, and why some people survive nuclear bombs. Genes illuminate everything from JFK's bronze skin (it wasn't a tan) to Einstein's genius. They prove that Neanderthals and humans bred thousands of years more recently than any of us would feel comfortable thinking. They can even allow some people, because of the exceptional flexibility of their thumbs and fingers, to become truly singular violinists.
Kean's vibrant storytelling once again makes science entertaining, explaining human history and whimsy while showing how DNA will influence our species' future.

THE NEW YORK TIMES BESTSELLER FROM THE WINNER OF THE 2021 PULITZER PRIZE Your body is teeming with tens of trillions of microbes. It's an entire world, a colony full of life. In other words, you contain multitudes. They sculpt our organs, protect us from diseases, guide our behaviour, and bombard us with their genes. They also hold the key to understanding all life on earth. In I Contain Multitudes, Ed Yong opens our eyes and invites us to marvel at ourselves and other animals in a new light, less as individuals and more as thriving ecosystems. You'll never think about your mind, body or preferences in the same way again. 'Super-interesting... He just keeps imparting one surprising, fascinating insight after the next. I Contain Multitudes is science journalism at its best' Bill Gates SHORTLISTED FOR THE WELLCOME BOOK PRIZE 2017 SHORTLISTED FOR THE ROYAL SOCIETY SCIENCE BOOK PRIZE 2017

Revised for the Seventh Edition, this full-color atlas is packaged with every new copy of the text, and includes 107 bone and 47 soft-tissue photographs with easy-to-read labels. This new edition of the atlas contains a brand new comprehensive histology photomicrograph section featuring over 50 slides of basic tissue and organ systems. Featuring photos taken by renowned biomedical photographer Ralph Hutchings, this high-quality photographic atlas makes an excellent resource for the classroom and laboratory, and is referenced in appropriate figure legends throughout the text.

Evolution is among the most central and most contested of ideas in the history of anthropology. This book charts the fortunes of the idea from the mid-nineteenth century to recent times. By comparing biological, historical, and anthropological approaches to the study of human culture and social life, it lays the foundation for their effective synthesis. Far ahead of its time when first published, the book anticipates debates at the forefront of contemporary thinking. Revisiting the work after almost thirty years, Tim Ingold offers a substantial new preface that describes how the book came to be written, how it was received and its bearing on later developments. Unique in scope and breadth of theoretical vision, Evolution and Social Life cuts across the boundaries of natural science and the humanities to provide a major contribution both to the history of anthropological and social thought, and to contemporary debate on the relationship between human nature, culture, and social life.

Misanthropology: Science, Pseudoscience, and the Study of Humanity introduces students to key concepts in critical thinking across the four core branches of anthropology: cultural, linguistic, biological, and archaeological. It combines a critical analysis of anthropology as a field with current concepts in scientific skepticism. By deconstructing a range of global case studies in which anthropological research runs aground, the book teaches students to distinguish between legitimate science and pseudoscience. It covers key concepts in critical thinking and rigorous research, such as cognitive biases and logical fallacies, data collection and consensus, probabilistic thinking, as well as political, nationalist, racist biases. Students learn not only how to apply these concepts to anthropological research and fieldwork, but also to their consumption of everyday information. This book will appeal to anthropology students and will be particularly useful for instructors of introductory anthropology courses, as well as instructors of courses across the humanities and social sciences focused on inculcating critical thinking skills.

Covers significant discoveries in the rapidly advancing field of metals and genetics. The aim of this volume is to bring together investigators from diverse fields of clinical medicine, genetics, biochemistry, and chemistry to reflect on the broad implications of direct and indirect interactions of metals and genetic components. The volume is divided into five sections. The first discusses genetic response to environmental exposure to metals. The section on metal carcinogenesis and metal caused DNA damage presents the latest advances in our knowledge of the molecular mechanisms of metal-induced mutagenis and carcinogenesis. A section is devoted to metals and neurodegenerative diseases. The identification of several disease genes related to metals is a major breakthrough in recent years. The section on genetics and biochemistry of metal-related diseases presents authoritative accounts of current (1999) information on both inherited and acquired metal-related diseases. They have discussed the genetics and pathophysiology of these diseases and reported the cloning, expression, purification, and characterization of gene products.

As scholars debate the most appropriate way to teach evolutionary theory, Constance Areson Clark provides an intriguing reflection on similar debates in the not-too-distant past. Set against the backdrop of the Jazz Age, God-or Gorilla explores the efforts of biologists to explain evolution to a confused and conflicted public during the 1920s. Focusing on the use of images and popularization, Clark shows how scientists and anti-evolutionists deployed schematics, cartoons, photographs, sculptures, and paintings to win the battle for public acceptance. She uses representative illustrations and popular media accounts of the struggle to reveal how concepts of evolutionary theory changed as they were presented to, and absorbed into, popular culture. Engagingly written and deftly argued, God-or Gorilla offers original insights into the role of images in communicating-and miscommunicating-scientific ideas to the lay public.

How and where did our ancestors live during the 8000 years between the end of Ice Age and the arrival of the Romans in AD 43? In tracing the variety and development of prehistoric settlements from the hunter-gatherers of the Mesolithic to the tribes of the Iron Age, Dr Bewley takes a fresh look at all the key sites, from Star Carr in Yorkshire and other Mesolithic settlements, the causewayed camps of the Neolithic, the great Bronze Age landscapes to the Dartmoor and other land divisions, and the hillforts and farmsteads of the Iron Age. Throughout he concentrates on the close relationship between the individual site and the wider landscape, and on the ways that archaeologists discover, interpret and constantly reinterpret prehistoric settlements.

There's a silent epidemic in western civilization, and it is right under our noses. Our jaws are getting smaller and our teeth crooked and crowded, creating not only aesthetic challenges but also difficulties with breathing. Modern orthodontics has persuaded us that braces and oral devices can correct these problems. While teeth can certainly be straightened, what about the underlying causes of this rapid shift in oral evolution and the health risks posed by obstructed airways? Sandra Kahn and Paul R. Ehrlich, a pioneering orthodontist and a world-renowned evolutionist, respectively, present the biological, dietary, and cultural changes that have driven us toward this major health challenge. They propose simple adjustments that can alleviate this developing crisis, as well as a major alternative to orthodontics that promises more significant long-term relief. Jaws will change your life. Every parent should read this book.

Biology of Aging, Second Edition presents the biological principles that have led to a new understanding of the causes of aging and describes how these basic principles help one to understand the human experience of biological aging, longevity, and age-related disease. Intended for undergraduate biology students, it describes how the rate of biological aging is measured; explores the mechanisms underlying cellular aging; discusses the genetic pathways that affect longevity in various organisms; outlines the normal age-related changes and the functional decline that occurs in physiological systems over the lifespan; and considers the implications of modulating the rate of aging and longevity. The book also includes end-of-chapter discussion questions to help students assess their knowledge of the material. Roger McDonald received his Ph.D. from the University of Southern California and is Professor Emeritus in the Department of Nutrition at the University of California, Davis. Dr. McDonald's research focused on mechanisms of cellular aging and the interaction between nutrition and aging. His research addressed two key topics in the field: the relationship between dietary restriction and lifespan, and the effect of aging on circadian rhythms and hypothalamic regulation. You can contact Dr. McDonald at [email protected]. Related Titles Ahmad, S. I., ed. Aging: Exploring a Complex Phenomenon (ISBN 978-1-1381-9697-1) Moody, H. R. & J. Sasser. Gerontology: The Basics (ISBN 978-1-1387-7582-4) Timiras, P. S. Physiological Basis of Aging and Geriatrics (ISBN 978-0-8493-7305-3)

'Gets right to the heart of what makes us what we are. Read it!' Angela Saini, author of Inferior and Superior: The Return of Race Science The popular science equivalent of Who Do You Think You Are? Popular science master Brian Clegg's new book is an entertaining tour through the science of what makes you you. From the atomic level, through life and energy to genetics and personality, it explores how the billions of particles which make up you - your DNA, your skin, your memories - have come to be. It starts with the present-day reader and follows a number of trails to discover their origins: how the atoms in your body were created and how they got to you in space and time, the sources of things you consume, how the living cells of your body developed, where your massive brain and consciousness originated, how human beings evolved and, ultimately, what your personal genetic history reveals.