Reproduction plays a huge part in many people's lives, but often little is understood about the biological processes involved and the larger impact of reproductive choices. This book offers an accessible, comprehensive introduction to this fascinating subject. Irina Pollard takes a unique, interdisciplinary perspective, describing in detail the biology of human reproduction, but also covering in depth the impact of procreational behavior on human social structures, the environment, and health. This compelling and authoritative account is the first to draw together in a single volume these two disparate yet intimately connected strands of the story of human reproduction. The book covers fertility and infertility, sexual behavior and pheromones, sperm creation, maternal physiology during pregnancy, fetal development, the biology of breast feeding, and the impact of parental behavior on the physiology of the newborn, as well as population dynamics, artificial control of fertility, the AIDS epidemic, the effects of nutrition and exercise on reproductive behavior, and the causes of birth defects, including abuse of substances such as nicotine, alcohol, and caffeine. This book is an ideal text for undergraduate and graduate students studying biology, medicine, anthropology, human ecology, population dynamics, and public health. It is also an engrossing and enlightening source of information for a wide range of general readers including prospective parents, pregnant mothers, teenagers, and anyone wishing a concise, up-to-date review of human reproductive biology.

It is only during the last decade that the functions of sinusoidal endothelial cells, Kupffer cells, hepatic stellate cells, pit cells and other intrahepatic lymphocytes have been better understood. The development of methods for isolation and co-culturing various types of liver cells has established that they communicate and cooperate via secretion of various intercellular mediators. This monograph summarizes multiple data that suggest the important role of cellular cross-talk for the functions of both normal and diseased liver. Special features of the book include concise presentation of the majority of detailed data in 19 tables. Original schemes allow for the clear illustration of complicated intercellular relationships. This is the first ever presentation of the newly emerging field of liver biology, which is important for hepatic function in health and disease and opens new avenues for therapeutic interventions.

Seasonality has effects on a wide range of human functions and activities, and is important in the understanding of human environment relationships. In this volume, distinguished contributors, including human biologists, anthropologists, physiologists and nutritionists consider many of the different ways in which seasonality influences human biology and behaviour. Topics addressed include the influence of seasonality on hominid evolution, seasonal climatic effects on human physiology, fertility and physical growth, seasonality in morbidity, mortality and nutritional state, and seasonal factors in food production, modernisation and work organisation in Third World economics. This book will be of interest to graduate students and researchers in human biology, anthropology and nutrition.

We like to think of ourselves as highly evolved. But if we are evolution's greatest creation, why are we so badly designed? We have retinas that face backward, we must find vitamins and nutrients in our diets that other animals simply make for themselves and millions of us can't reproduce successfully without help from modern science. And that's just the beginning of the story. Biologist Nathan H. Lents takes us on an entertaining and illuminating tour of our four-billion-year-long evolutionary saga, and shows us how each of our flaws tells us a story about our species' history.

This volume looks at the relationship between specific aspects of Third World cities and human health. Rapid and extensive urbanization of the less developed nations is perhaps the most dramatic demographic phenomenon of our times, but its impact on human biology is not well understood. Here, a cross-section of work is presented on this subject allowing human biologists, urban planners, public health workers and other specialists to assess our knowledge and the current approaches available to increase it. Contributions fall into two groups: studies of urban ecology including the social, economic and physical domains, and studies of biological responses to the urban environment. Health is not merely the absence of specific diseases, but is construed more broadly to include a wide range of biological parameters that are correlated with various states of sub-optimal health. These include patterns of child growth and development, frequencies of specific diseases, nutritional status, immunological characteristics and physiological parameters. This important volume will be of interest to a wide range of researchers and academics, including human biologists, anthropologists, healthcare professionals, human geographers, urban and regional planners, and economists.

Physical activity and exercise affect many dimensions of health. This book presents an up-to-date and wide ranging account of the key issues of the biology of physical activity and health. The context is set by considering the comparative and temporal aspects of activity in humans. There follows an examination of the concepts and methodological issues associated with activity, exercise, health, and fitness, as well as their interrelationships. Particular attention is given to activity in children, adolescents and the elderly, activity and weight maintenance, and the psychological effects of activity. The book ends with an overview of current and future leisure life styles.

Nutrition has become a hot topic, in the media as well at the market place. But how much of the information given to the consumer is hype and how much is accurate? In Taking the Fear out of Eating, published in 1993, two established scientists have distilled the information from thousands of scientific studies into a succinct, easily read description of what is known, what is merely suspected and, equally important, what is not known, about nutrition and how food choices might affect health. The book takes a hard look at both sides of the controversy about the connection between food and health, with particular emphasis on diet and the chronic diseases of cancer and heart disease. Food is, of course, essential to our survival but our food supply is often portrayed as dangerous - loaded with additives, pesticides, salt, sugar, fat and cholesterol. Taking the Fear out of Eating puts these topics into perspective in an authoritative and entertaining manner. It is not intended as a 'self-help' book but rather as a means to make the reader a participating partner with health professionals.

Nutrition has become a hot topic, in the media as well at the market place. But how much of the information given to the consumer is hype and how much is accurate? In Taking the Fear out of Eating, published in 1993, two established scientists have distilled the information from thousands of scientific studies into a succinct, easily read description of what is known, what is merely suspected and, equally important, what is not known, about nutrition and how food choices might affect health. The book takes a hard look at both sides of the controversy about the connection between food and health, with particular emphasis on diet and the chronic diseases of cancer and heart disease. Food is, of course, essential to our survival but our food supply is often portrayed as dangerous - loaded with additives, pesticides, salt, sugar, fat and cholesterol. Taking the Fear out of Eating puts these topics into perspective in an authoritative and entertaining manner. It is not intended as a 'self-help' book but rather as a means to make the reader a participating partner with health professionals.

This interdisciplinary work demonstrates, by steadfast attention to corporeal matters of fact, how the concept of power and of power relations is rooted in bodily life, in animate form. It first shows how Foucault's "optics of power" is Sartre's "The Look" writ large, and proceeds to explain how optics of power are undergirded by a "power of optics" which has its roots in our primate evolutionary heritage. The exploration of an evolutionary genealogy leads in turn into extended examinations and exemplifications of corporeal and intercorporeal archetypes. Moving easily through biological, anthropological and psychological domains, and informed by keen philosophical reflection, "The Roots of Power" aims to show how the personal and political are fundamentally joined in the body, that is, how the political defines us both as creatures of a natural history and as culturally - and individually - groomed bearers of meaning. Sheets-Johnstone assesses the complex of topics that progressively surfaces such as females' being receptive "year-round", male threat/female vulnerability, Sartre's characterisation of females' being "in the form of a hole", and proposed relationships between aggression and sex. In addition, she shows through detailed analyses of Derrida's absencing of the living body from the scene of grammatology, and of sociobiologists' explanations of rape as adaptive behaviour how the tenets of postmodernism and sociobiology preclude insight into the personal-political equation. "The Roots of Power" concludes with an extended critical meditation on Lacan's psychoanalytic, showing not only how it is rooted in idiosyncratic archetypal elaborations but how, in its scientisation of life, pedestalling of human language, and silencing of the living body, it is a microcosm of 20th-century Western practices and ideologies.

Preparatory work for this monograph started in 1988 and 1989. The motive was provided by certain incongruities in the illustra- tion of descensus testis for the chapter "Entwicklung der Genital- organe" in the book Humanembryologie. The evoked discussion was reason enough for our own re- search on the phenomenon and uncertainties of testicular des- cent in human. The basis ofthese investigations was the collection of human embryos founded by Prof. Hinrichsen in 1970 at the Department of Anatomy and Embryology, Ruhr-University Bo- chum. The preparation of the material used in this paper has been done with the help of many staff members of our department to whom we feel obliged. We are especially indebted to Prof. Hin- richsen who prepared the foetuses and took the first steps of this project. We wish also to acknowledge Dr. Heinz Jiirgen Jacob for careful fixation and microdissection of specimens intended for scanning electron microscopy. Weare also grateful to Mrs. Vera Mannheim for her involvement and her sensitivity in making scanning electron micrographs, and Mrs. Antje Jaeger for provid- ing an expert and skilful photographic technique especially in the setting up of micrographs. Our thanks are also due to Mrs. Marion Kohn for skilful technical assistance and to all those technical assistants who worked in our department during the past 25 years and who were engaged in providing the serial sec- tions. The English text has been thoroughly revised by Prof. Dr.

Have you ever done something stupid, dangerous or self-sabotaging just to get one over someone else? Most of us have. Simon McCarthy-Jones draws on psychology, current affairs, literature and genetics to illuminate – whether we admit it or not – our spiteful side. What is that part of us that secretly wants our friends to fail? Did Americans put Trump in the White House just to stick it to Hillary Clinton? And then there are the legion of stories about toxic behaviour in supermarkets and over the privet hedge, ramping up to incendiary divorces, vicious business practices, backbiting politics and scorched-earth terrorism. There’s a hopeful message too – the upside of our dark side. Spite can drive us forward, and Simon provides a fresh perspective on the concept by showing the evolutionary benefits of spite as a social leveller, an enabler of defiance, a wellspring of freedom and a vital weapon in our everyday armoury.

When Did I Begin? investigates the theoretical, moral, and biological issues surrounding the debate over the beginning of human life. With the continuing controversy over the use of in vitro fertilization techniques and experimentation with human embryos, these issues have been forced into the arena of public debate. Following a detailed analysis of the history of the question, Reverend Ford argues that a human individual could not begin before definitive individuation occurs with the appearance of the primitive streak about two weeks after fertilization. This, he argues, is when it becomes finally known whether one or more human individuals are to form from a single egg. Thus, he questions the idea that the fertilized egg itself could be regarded as the beginning of the development of the human individual. The author also differs sharply, however, from those who would delay the beginning of the human person until the brain is formed, or until birth or the onset of conscious states.

This completely revised edition provides a synthesis of the forces that shaped the evolution of the human growth pattern, the biocultural factors that direct its expression, the intrinsic and extrinsic factors that regulate individual development, and the biomathematical approaches needed to analyze and interpret human growth. After covering the history, philosophy and biological principles of human development, the book turns to the evolution of the human life cycle. Later chapters explore the physiological, environmental and cultural reasons for population variation in growth, and the genetic and endocrine factors that regulate individual development. Using numerous historical and cultural examples, social-economic-political-economic forces are also discussed. A new chapter introduces controversial concepts of community effects and strategic growth adjustments, and the author then integrates all this information into a truly interactive biocultural model of human development. This remains the primary text for students of human growth in anthropology, psychology, public health and education.

Most philosophers writing about personal identity in recent years claim that what it takes for us to persist through time is a matter of psychology. In this groundbreaking new book, Eric Olson argues that such approaches face daunting problems, and he defends in their place a radically non-psychological account of personal identity. He defines human beings as biological organisms, and claims that no psychological relation is either sufficient or necessary for an organism to persist. Rejecting several famous thought experiments dealing with personal identity, he instead argues that one could survive the destruction of all of one's psychological contents and capabilities as long as the human organism remains alive.

The health of a population is most accurately reflected in the rate of growth of its children. It is this theme which underlies the analysis and presentation of what is by far the largest compilation of growth data ever assembled. The first edition, published in 1976, included all known reliable recent results on height, weight, skinfolds and other body measurements from all parts of the globe. In this edition, the very numerous measurements taken between 1976 and 1988 have been included as well as the results of the large number of new studies made on rate of maturation as evinced by bone age and pubertal development stages. Many sections of the book dwell on disentangling the effects of the environment and heredity on growth, and thus answer the question of whether one universal standard suffices for all peoples of the world, or whether different populations (such as races or nations) should each have their own optimal growth standards. Written by practical people with experience of the problems in developing countries, this book explains in simple terms the different sorts of growth surveys, how to set about making them, and which sort to choose. All who are professionally concerned with child health should read it.

The health of a population is most accurately reflected in the rate of growth of its children. This theme, prevalent in this book, underlies the analysis and presentation of what is by far the largest compilation of growth data ever assembled in one source. The first edition, published in 1976, included all known reliable recent results on height, weight, skinfolds, and other body measurements from all parts of the globe. In this edition, numerous subsequent measurements taken between 1976 and 1988 have been included, as well as the results of a large number of new studies made on rate of maturation as evinced by bone age and pubertal development stages. Many sections of the book dwell on disentangling the effects of the environment and heredity on growth, and attempt to answer the question of whether one universal standard suffices for all peoples of the world or whether different populations (such as races or nations) should each have their own optimal growth standards.

Evolutionary Medicine is based upon the view that many contemporary social, psychological, and physical illnesses are related to an incompatibility between current human lifestyles and environments and the conditions under which human biology developed. This book, featuring contributions from many of the leading workers in this developing area, provides a good introduction and overview to this emerging field.

Fertility in animals reflects access to scarce resources, such as food and territory. In humans the situation is more complex. Patterns of breast feeding, contraception and ideas about age at marriage and desired family size all affect fertility. The relation between these and access to scarce resources such as housing and employment, via income, education and other factors which affect status, is explored in this book, which aims to bridge the gap between socioecology and population demography by showing how animals and humans adjust their fertility to environmental conditions.

The first major account of the somatotyping field in over thirty years, this volume presents a comprehensive history of somatotyping, beginning with W.H. Sheldon's introduction to the method in 1940. The controversies regarding the validity of Sheldon's method are described, as are the various attempts to modify the technique, particularly the Heath-Carter method, which has come into widespread use. Somatotyping is a method of description and assessment of the body on three shape and composition scales: endomorphy (relative fatness), mesomorphy (relative musculoskeletal robustness), and ectomorphy (relative linearity). The book reviews present knowledge of somatotypes around the world, how they change with growth, aging and exercise, and the contributions of genetics and environment to the rating. Also reviewed are the relationships among somatotypes and sport, physical performance, health and behavior.

Praise for Howard Bloom and GLOBAL BRAIN

"With this bold vision of evolution and human behavior, Bloom has raced ahead to explore possibilities that the timid scientific herd may well be forced to follow."––David Sloan Wilson, Coauthor of Unto Others: The Evolution and Psychology of Unselfish Behavior

"Filled with scientific firsts."––Elizabeth Loftus, past president, American Psychological Society

"I doubt there is any stronger intellect than Bloom’s on the planet."––Joseph Chilton Pierce

"A soaring song of songs about the amorous origins of the world and its almost medieval urge to copulate."––Kevin Kelly, Editor-at-Large, Wired

"A superbly written and totally original argument. . . . A must-read."––Robin Fox, coauthor of The Imperial Animal

"As someone who has spent forty years in psychology with a long-standing interest in evolution, I’ll just assimilate Howard Bloom’s accomplishment and my amazement."––David Smillie, Duke University

"Howard Bloom is next on a very short list that includes Darwin, Freud, Einstein, and Buckminster Fuller."––Richard Metzger

"Howard Bloom may be the new Stephen Hawking."––Aaron Hicklin, Gear

"You have not lived until you have interacted with Howard Bloom."––James Brody, organizer of the "Healing the Moral Animal" seminars

"Bloom’s concept of collective information processing may startle skeptical readers with its explanatory power."––Publishers Weekly

"I am awestruck."––Douglas Rushkoff, author of Media Virus, Coercion, and Ecstasy Club.

This book provides accurate concise information concerning the evaluation and the treatment of patients with sleep problems. Because management of sleep disorders requires an understanding of sleep itself, the first portion discribes aspects of normal sleep. The remainder of the book follows an approach based on the clinical method, in which the chief complaints (the symptoms and the signs) and the psychosocial and the medical background of the individual are used, in conjunction with an understanding of the neurobiological and psychological basis of sleep disorders, to formulate a clinical assessment. The results of polysomnographic studies and other laboratory tests supplement and redefine clinical information and assist with consideration of treatment options.

Scientists now understand that cancer is a genetic disease and cutting -edge molecular therapies are making their way from the laboratory into clinical practice. Introduction to Oncogenes and Molecular Cancer Medicine provides the physician with a solid understanding of molecular biology and its applications for the diagnosis and treatment of cancer. The book reviews the basic molecular principles and the basic principles of cancer medicine, including controls of cell growth and senescence, carcinogenesis, tumorogenesis, and epidemiology. The second part of the book gives clinical examples to demonstrate the basic science principles, including chapters on leukemia, colon cancer, and breast cancer. A chapter on molecular diagnostics and screening plus a chapter on new molecular anti-cancer therapies give the reader a look at current cutting-edge therapies as well as as the future of molecular cancer medicine. A useful glossary defines new terminology at-a-glance. Introduction to Oncogenes and Molecular Cancer Medicine is for all physicians seeking a better understanding of the modern molecular principles of cancer medicine. Written in a user-friendly, conversational format, this text will be welcomed by all physicians eager to sharpen their own understanding of molecular cancer medicine as well as to help them provide patients with balanced information on the advances and limitations of current treatment options.

Based on a two day symposium in the annual Society for the Study of Human Biology Ssymposium Series, this book covers a wide spectrum of growth physiology, and presents a state-of-art review of human auxology, from factors affecting cellular growth, through nutritional factors affecting the growth of the infant, to endocrine and other factors affecting the growth of the child before and after adolescence.

The polymerase chain reaction (PCR) is one of the most important molecular biological methods ever devised, with numerous applications to cli- cal molecular medicine. Since its description in 1985, PCR has undergone tremendous improvements, and many variations on the basic PCR theme have been published. With such a large volume of PCR-related literature, a clinical scientist wishing to use the technique will have a difficult task loc- ing the relevant information to implement it effectively. There is thus clearly a need for an up-to-date volume with detailed protocols to facilitate the setting up of those techniques most relevant to clinical applications. Unlike some other books on this topic, Clinical Applications of PCR includes only methods that are of direct relevance in clinical settings. The book is organized in three parts: an introductory section, a section on general methodology, and a final section with specific clinical applications. The first section covers the basic principles of PCR and is most useful to those new to molecular diagnosis. The next chapter includes useful tips for setting up a PCR laboratory. Section 2 then outlines some of the most commonly used PCR-based techniques in molecular diagnosis. Section 3 includes carefully chosen examples that represent typical applications of PCR in diverse clinical fields, encompassing hematology, oncology, genetics, and microbiology.

The current explosive progress in molecular biological research can be definitively traced to the development of molecular cloning technology. The ability to insert specific gene sequences into cloning vectors and their subse quent expansion is the cornerstone of modem molecular biology. A direct practical outcome of molecular cloning technology is its application to ex press specific recombinant genes. Currently, recombinant gene products are used in a wide spectrum of applications, including gene therapy, production of bioactive pharmaceuticals, synthesis of novel biopolymers, in agriculture and animal husbandry, and so on. A fundamental requirement for successful recombinant gene expression is the design of the cloning vector and the choice of the host organism for expression. Recombinant Gene Expression Protocols grows out of the need for a laboratory manual that provides the reader the background and rationale, as well as the practical protocols for the preparation of "expression constructs" and their introduction into appropriate host cells and/or organisms. The chap ters in this book are grouped by their expression hosts, including E. coli, yeast, mammalian cells, nonmammalian eukaryotes such as plants, Xenopus, and insects, as well as in transgenic organisms. In-depth information is presented on the important characteristics of expression cloning vectors and the various methods for efficiently introducing expression constructs into target cells and/ or organisms. Throughout Recombinant Gene Expression Protocols, the authors have consistently striven for a balanced presentation of both background informa tion and actual laboratory details.