The peoples of the high-altitude regions of the world have long fascinated both scientists and laymen from the lowlands. This book, while it draws heavily on the research conducted in the International Biological Programme, is a comprehensive review of our knowledge about the biology of the high-altitude peoples of the world. While several other accounts have considered the general problems of human populations living and working under the reduced oxygen pressure found at high altitude, this volume is the first attempt to analyse the total human biology of the peoples of the world living in extremely high mountain areas. The contributors are experts in a variety of topics within human biology. In addition, each has conducted personal research in the high-altitude areas such as the Andes, Ethiopian highlands, Himalayas or Tien Shan mountains. While the book is not designed for the layman, technical language has been reduced in an effort to make the various topics covered comprehensible to professionals working in any branch of the sciences concerned with man.

The processes that control senescence have been the subject of more then a century of serious biological research. Two institutions closely involved in this programme, the Society for the Study of Human Biology and the British Society for Research in Ageing, held a joint symposium in 1984 to consider human ageing and longevity from an interdisciplinary point of view. The resulting book has four main sections: the evolution and genetics of ageing, biological age assessment, demographic and social aspects, and the nutritional and physiological aspects of ageing and longevity. The fundamental nature of the subject will generate interest across a wide range of biological and medical disciplines.

First published in 1977, this volume is a collection of eleven studies conducted during the International Biological Programme on the biological structure of human populations. They deal particularly with population genetics, demography and ecology, and discuss the experimental strategies to be adopted when making such studies. Each chapter is in the form of a broad review aimed at those wanting to understand human population biology. The volume is an international one, both in terms of its authorship and of the populations studied, and the projects discussed represent the whole variety of problems and approaches tackled by the IBP investigators interested in population biology. In short, this book represents an excellent evaluation of human biology in the mid-twentieth century. It will be of importance to university teachers, research workers and graduate students in anthropology and human biology.

One of the objectives of investigations carried out within the Human Adaptability section of the International Biological Programme was to obtain comparable data on population characteristics over a wide range of ecosystems. This volume provides a brief survey of the variables affecting the physiological work capacity of various populations. The items considered include body weight, fatness, maximum oxygen intake, muscular strength, and the process of oxygen transport from the air to the working muscles. The discussion is based largely on data collected under the auspices of the IBP, using methods standardised for the programme. The influence of race, heredity, environment and disease are considered, and a detailed analysis is made of various classes of athlete. The material will be useful to human and environmental physiologists, anthropologists, and those interested in physical education.

Fertility in animals reflects access to scarce resources, such as food and territory. In humans the situation is more complex. Patterns of breast feeding, contraception and ideas about age at marriage and desired family size all affect fertility. The relation between these and access to scarce resources such as housing and employment, via income, education and other factors that affect status, is explored. In this book, the gap between socio-ecology and population demography is bridged, by showing how animals and humans adjust their fertility to environmental conditions.

This volume looks at the relationship between specific aspects of Third World cities and human health. Rapid and extensive urbanization of the less developed nations is perhaps the most dramatic demographic phenomenon of our times, but its impact on human biology is not well understood. Here, a cross-section of work is presented on this subject allowing human biologists, urban planners, public health workers and other specialists to assess our knowledge and the current approaches available to increase it. Contributions fall into two groups: studies of urban ecology including the social, economic and physical domains, and studies of biological responses to the urban environment. Health is not merely the absence of specific diseases, but is construed more broadly to include a wide range of biological parameters that are correlated with various states of sub-optimal health. These include patterns of child growth and development, frequencies of specific diseases, nutritional status, immunological characteristics and physiological parameters. This important volume will be of interest to a wide range of researchers and academics, including human biologists, anthropologists, healthcare professionals, human geographers, urban and regional planners, and economists.

As widespread social transformations have been paralleled by gains in health and life expectancy through public health and other improvements, a variety of other challenges to health have emerged, particularly in lifestyle related, behaviourally mediated changes in rates of chronic disease. Hormones, Health and Behavior looks at the relationship of human biology and human society at the intersection of behavior, hormones and health. There is both scientific interest and practical urgency behind the ideas and findings presented here, as the need for a socio-ecological view of function and well-being has become more apparent. This book documents an emerging understanding of how hormones create linkage between behavior or social life and health. It will inform graduate students and researchers interested in human sciences, human development, anthropology, epidemiology, public environmental and reproductive health.

Measuring Behaviour is the established go-to text for anyone interested in scientific methods for studying the behaviour of animals or humans. It is widely used by students, teachers and researchers in a variety of fields, including biology, psychology, the social sciences and medicine. This new fourth edition has been completely rewritten and reorganised to reflect major developments in how behavioural studies are conducted. It includes new sections on the replication crisis, covering Open Science initiatives such as preregistration, as well as fully up-to-date information on the use of remote sensors, big data and artificial intelligence in capturing and analysing behaviour. The sections on the analysis and interpretation of data have been rewritten to align with current practices, with advice on avoiding common pitfalls. Although fully revised and revamped, this new edition retains the simplicity, clarity and conciseness that have made Measuring Behaviour a classic since the first edition appeared more than 30 years ago.

The first insights into the site and mechanisms of RNA process- ing to functional mRNA in eukaryotic cells came from the group of Georgiev (Lukanidin et al. 1972) who demonstrated the association of rapidly labelled, heterogeneous nuclear RNA (hnRNA) with a limited number of specific proteins in the cell nucleus. These "informofers", i. e. packaged precursors of mRNA (pre-mRNA or hnRNA), are in a form presumably amenable to the action of nucleases. With the availability of better analytical techniques, the considerable heterogeneity of hnRNA associated proteins was revealed (Niessing and Sekeris 1970), suggesting a role that was more composite, rather than solely structural, for these proteins. Later studies investigated the RNA binding behavior of these proteins (Schenkel et al. 1988, 1989; Wilk et al. 1983). For a long time, the small nuclear RNAs, well characterized with respect to primary structure (reviewed by Reddy and Busch 1983), were naively ignored regarding their function. Several events then set the stage for a detailed study of the intricate mechanisms of the splicing process and other steps involved in hnRNA processing: (1) The demonstration of a second class of nuclear ribonucleoproteins (RNPs), composed of small nuclear RNAs (snRNAs) and another characteristic group ofheterogene- ous proteins (Lerner et al. 1980; Guialis et al. 1983); (2) the detec- tion of the association of snRNPs with hnRNPs by virtue of base pairing between hnRNA and snRNA (Flytzanis et al.

What are you? Obviously, you are a person with human ancestors that can be plotted on a family tree, but you have other identities as well. According to evolutionary biologists, for example, you are a member of the species Homo sapiens. To a microbiologist, though, you are a collection of cells, each of which has its own cellular ancestry. A geneticist might point out that besides these identities, you can be understood as a gene-replication machine, which can be plotted on a "genetic tree." Finally a physicist will give a rather different answer to the identity question: you can be understood as a collection of atoms, each of which has a very long history. Some have been around since the Big Bang, and others are the result of nuclear fusion that took place within a star. Not only that, but most of your atoms belonged to other living things before joining you. From your atoms' point of view, then, you are just a way station on a multibillion-year-long journey. You: A Natural History offers a multi-disciplinary investigation of your hyper-extended family tree, going all the way back to the Big Bang. And while your family tree may contain surprises, your hyper-extended history contains some truly amazing stories. As the result of learning more about who and what you are, and about how you came to be here, you will likely see the world around you with fresh eyes. You will also become aware of all the one-off events that had to take place for your existence to be possible: stars had to explode, the earth had to be hit 4.5 billion years ago by a planetesimal and 65 million years ago by an asteroid, microbes had to engulf microbes, the African savanna had to undergo climate change, and of course, any number of your direct ancestors had to meet and mate. It is difficult, on becoming aware of just how contingent your own existence is, not to feel very lucky to be part of our universe.

Building on the success of the second edition, this truly accessible textbook comprehensively covers the 2008 AS and A2 level Human Biology specifications for all the main UK exam boards.The book also has a companion website which is free to book users providing extra resources. Written by authors with many years' experience of teaching, examining and writing, this is an ideal resource for class or independent study. The book includes the following features: How Science Works feature boxes focus on this key element of the new specifications. Stretch and Challenge boxes challenge more able students, enabling them to achieve the highest grades. Science in Context boxes encourage students to relate their learning to the world around them. Summaries at the end of every chapter help students with revision. Test Yourself questions throughout the text enable students to monitor their own progress in preparation for their exams. Remember This boxes highlight the key facts. The website provides the following additional resources: Practice questions (and answers) allow students to test their understanding of the material just covered. How Science Works assignments allow students to prepare for the How Science Works element of the new AS and A2 Human Biology exams.

Physical activity and exercise affect many dimensions of health. This book presents a wide-ranging account of the key issues of the biology of physical activity and health. The context is set by considering the comparative and temporal aspects of activity in humans. There follows an examination of the concepts and methodological issues associated with activity, exercise, health and fitness, as well as their interrelationships. Particular attention is given to activity in children, adolescents and the elderly, activity and weight maintenance, and the psychological effects of activity. This topical volume will be of interest to human biologists, biological anthropologists, human physiologists, sports scientists, psychologists, and healthcare professionals involved in preventative medicine, public health, geriatrics, occupational health and community medicine.

What are the health consequences of a transition from an active 'hunter-gatherer' lifestyle to that of sedentary modern living? In this book, the impact of 'modernization' is assessed in various populations in the circumpolar regions. The hazards of living in polar regions, and the adaptations shown culturally, behaviourally and physically by the indigenous peoples are examined and the effect of changes in habitual activity, diet, and general lifestyle due to more urban living patterns on the body composition, pulmonary function and susceptibility to disease discussed. The implications of this switch are important not only for all those concerned about the survival of indigenous communities around the world, but for all of us living in an increasingly sedentary, urban environment. Anthropologists, physiologists and those interested in population fitness will find this a comprehensive and valuable volume.

This volume considers the genetic variability of human populations, particularly in the tropics: its origins and maintenance, and its contribution to the phenotypic variability of complex characters. The first section deals with the ways of analysing genetic variation and provides a valuable review of relevant developments in molecular biology. The origin and maintenance of genetic diversity is considered in the second section with data presented for Pacific, African, Asian and Central American populations. The final section concerns characters in which the genetic contribution to variability is complex and shows how such characters may be used to elucidate biological problems of affinity and differentiation, of adaptation and survival. Published as part of the Decade of the Tropics research programme of the International Union of Biological Sciences, this volume will be of particular interest to human geneticists, physical and biological anthropologists.

This transformative guide completely breaks down our current understanding of biological sex and gender diversity. Introducing readers to seven variations of human sex, commonly considered intersex, the book challenges the myth that sex and gender are exclusively binary and explores the inherent diversity of biological sex and its relationship to gender identity and expression, and the impact this has on society. Examining historical, linguistic and socio-cultural understandings of sex and gender, as well as genetic and scientific definitions, the book is an important resource for dismantling gender and sexuality-based discrimination and promoting understanding and inclusivity. Co-written by one of the world's leading intersex activists and a highly respected scholar in biological sciences, and accompanied with detailed anatomical illustrations throughout, this pioneering text is the essential introduction to gender and sex diversity for gender studies, women's studies, biology and genetics courses, as well as professionals working with intersex and trans communities.

In 1901 William Bateson, Professor of Biology at Cambridge, published a renewed version of a lecture which he had delivered the year before to the Royal Horticultural Society in London (reprinted in the book as an appendix). In this lecture he recognized the importance of the work completed by Gregor Mendel in 1865, and brought it to the notice of the scientific world. Upon reading Bateson's paper, Archibald Garrod realized the relevance of Mendel's laws to human disease and in 1902 introduced Mendelism to medical genetics.

The first part of A Century of Mendelism in Human Genetics takes a historical perspective of the first 50 years of Mendelism, including the bitter argument between the Mendelians and the biometricians. The second part discusses human genetics since 1950, ending with a final chapter examining genetics and the future of medicine. The book considers the genetics of both single-gene and complex diseases, human cancer genetics, genetic linkage, and natural selection in humanpopulations.

Besides being of general medical significance, this book will be of particular interest to departments of genetics and of medical genetics, as well as to historians of science and medicine.

Since the 18th century, one phenomenon, the proportion of the sexes at birth among human beings, has contributed to various developments such as the calculus of probabilities, administrative statistics, the moral and social sciences, the statistics of variability, post-Darwinian biology and Durkheimian sociology. This fact is brought to the critical attention of readers who rarely work together -- mathematicians, biologists, historians, social scientists and historians of the sciences -- along a three centuries European journey, meeting Sussmilch, Condorcet, Laplace, Fourier, Girou de Buzareingues, Poisson, Quetelet, Darwin, Dusing, Gini, Halbwachs or Fisher.

After a deconstruction of the past and present conditions of scientific understanding of human sex-ratio at birth, the authors are proposing a reconstruction of the dynamics of the phenomenon based on stochastics. This is an attempt in renewing our links with the oldest traditions of scholarly thinking, but too a kind of "well-tempered" reflexivity in today s work of objectivization.

Appendixes get to the reader the first expression of a trend of the sex ratio at birth to adjust towards balance between the sexes by Condorcet in 1793-1794; a comparison of passages that Darwin devoted in 1871 and 1874 to similar issues; and a sociological attempt of Halbwachs published in 1933."

This book shows that Holocene human ecosystems are complex adaptive systems in which humans interacted with their environment in a nested series of spatial and temporal scales. Using panarchy theory, it integrates paleoecological and archaeological research from the Eastern Woodlands of North America providing a paradigm to help resolve long-standing disagreements between ecologists and archaeologists about the importance of prehistoric Native Americans as agents for ecological change. The authors present the concept of a panarchy of complex adaptive cycles as applied to the development of increasingly complex human ecosystems through time. They explore examples of ecological interactions at the level of gene, population, community, landscape and regional hierarchical scales, emphasizing the ecological pattern and process involving the development of human ecosystems. Finally, they offer a perspective on the implications of the legacy of Native Americans as agents of change for conservation and ecological restoration efforts today.

Surnames are inherited in much the same way as are biological traits. Since surnames were generally adopted - in Europe during Medieval times - their distribution has become very uneven: analysis of the present geographic patterns provides an insight into the kind of redistribution of genes that has resulted from all the migrations of the intervening years. Using non-technical language and a minimum of mathematics, this book presents a lucid description and evaluation of these studies of the genetic structure of human populations. A special feature is the appendix which presents computer-generated maps and distribution diagrams of 100 common surnames in England and Wales.

This paperback edition of The End of the World, with a completely new preface, is a sobering assessment of the many disasters that scientists have predicted and speculated on as leading to apocalypse. In the first comprehensive survey, potential catastrophes - ranging from deadly diseases to high-energy physics experiments - are explored to help us understand the risks.

What makes a biological entity an individual? Jack Wilson shows that past philosophers have failed to explicate the conditions an entity must satisfy to be a living individual. He explores the reason for this failure and explains why we should limit ourselves to examples involving real organisms rather than thought experiments. This book explores and resolves paradoxes that arise when one applies past notions of individuality to biological examples beyond the conventional range and presents an analysis of identity and persistence. The book's main purpose is to bring together two lines of research, theoretical biology and metaphysics, which have dealt with the same subject in isolation from one another. Wilson explains an alternative theory about biological individuality which solves problems which cannot be addressed by either field alone. He presents a more fine-grained vocabulary of individuation based on diverse kinds of living things, allowing him to clarify previously muddled disputes about individuality in biology.

Anthropological genetics is a field that has been in existence since the 1960s and has been growing within medical schools and academic departments, such as anthropology and human biology, ever since. With the recent developments in DNA and computer technologies, the field of anthropological genetics has been redefined. This volume deals with the molecular revolution and how DNA markers can provide insight into the processes of evolution, the mapping of genes for complex phenotypes and the reconstruction of the human diaspora. In addition to this, there are explanations of the technological developments and how they affect the fields of forensic anthropology and population studies, alongside the methods of field investigations and their contribution to anthropological genetics. This book brings together leading figures from the field to provide an up-to-date introduction to anthropological genetics, aimed at advanced undergraduates to professionals, in genetics, biology, medicine and anthropology.

'Spellbinding . . . More than any other book, [Sentient] has made me think differently about the world this year.' - Financial Times Best Books of the Year The peacock mantis shrimp can throw a punch that can fracture aquarium walls. The great grey owl can hear many decibels lower than the human ear. The star-nosed mole's miraculous nose allows it to catch worms in as little as 120 milliseconds. In Sentient, Jackie Higgins assembles a menagerie of zoological creatures - from land, air, sea and all four corners of the globe - to understand what it means to be human. In it, we also meet the four-eyed spookfish and its dark vision, the vampire bat and its remarkable powers of touch, as well as the common octopus, the Goliath catfish and the duck-billed platypus. Each zoological marvel illustrates the surprising sensory powers that lie within us and enables us to engage with the world in ways we never knew possible. 'Lyrical and lucid . . . Higgins makes popular science accessible.' - Observer

Primate and Human Evolution provides a synthesis of the evolution and adaptive significance of human anatomical, physiological and behavioral traits. Using paleontology and modern human variation and biology, it compares hominid traits to those of other catarrhine primates both living and extinct, presenting a new hominization model that does not depend solely on global climate change, but on predictable trends observed in catarrhines. Dealing with the origins of hominid tool use and tool manufacture, it compares tool behavior in other animals and incorporates information from the earliest archaeological record. Examining the use of non-human primates and other mammals in modeling the origins of early human social behavior, Susan Cachel argues that human intelligence does not arise from complex social interactions, but from attentiveness to the natural world. This book will be a rich source of inspiration for all those interested in the evolution of all primates, including ourselves.

The emergence of the genus Homo is widely linked to the colonization of new highly seasonal savannah habitats. However, until now, our understanding of the possible impact of seasonality on this shift has been limited because we have little general knowledge of how seasonality affects the lives of primates. This book documents the extent of seasonality in food abundance in tropical woody vegetation, and then presents systematic analyses of the impact of seasonality in food supply on the behavioural ecology of non-human primates. Syntheses in this volume then produce for the first time broad generalizations concerning the impact of seasonality on behavioural ecology and reproduction in both human and non-human primates, and apply these insights to primate and human evolution. Written for graduate students and researchers in biological anthropology and behavioural ecology, this is an absorbing account of how seasonality may have affected an important episode in our own evolution.