The Human Genome Diversity Project (HGDP) was launched in 1991 by a group of population geneticists whose aim was to map genetic diversity in hundreds of human populations by tracing the similarities and differences between them. It quickly became controversial and was accused of racism and 'bad science' because of the special interest paid to sampling cell material from isolated and indigenous populations. The author spent a year carrying out participant observation in two of the laboratories involved and provides fascinating insights into daily routines and technologies used in those laboratories and also into issues of normativity, standardization and naturalisation. Drawing on debates and theoretical perspectives from across the social sciences, M'charek explores the relationship between the tools used to produce knowledge and the knowledge thus produced in a way that illuminates the HGDP but also contributes to our broader understanding of the contemporary life sciences and their social implications.

THE NEW YORK TIMES BESTSELLER FROM THE WINNER OF THE 2021 PULITZER PRIZE Your body is teeming with tens of trillions of microbes. It's an entire world, a colony full of life. In other words, you contain multitudes. They sculpt our organs, protect us from diseases, guide our behaviour, and bombard us with their genes. They also hold the key to understanding all life on earth. In I Contain Multitudes, Ed Yong opens our eyes and invites us to marvel at ourselves and other animals in a new light, less as individuals and more as thriving ecosystems. You'll never think about your mind, body or preferences in the same way again. 'Super-interesting... He just keeps imparting one surprising, fascinating insight after the next. I Contain Multitudes is science journalism at its best' Bill Gates SHORTLISTED FOR THE WELLCOME BOOK PRIZE 2017 SHORTLISTED FOR THE ROYAL SOCIETY SCIENCE BOOK PRIZE 2017

This volume features a collection of essays by primatologists, anthropologists, biologists, and psychologists who offer some answers to the question of what makes us human, i. e. , what is the nature and width of the gap that separates us from other primates? The chapters of this volume summarize the latest research on core aspects of behavioral and cognitive traits that make humans such unusual animals. All contributors adopt an explicitly comparative approach, which is based on the premise that comparative studies of our closest biological relatives, the nonhuman primates, provide the logical foundation for identifying human univ- sals as well as evidence for evolutionary continuity in our social behavior. Each of the chapters in this volume provides comparative analyses of relevant data from primates and humans, or pairs of chapters examine the same topic from a human or primatological perspective, respectively. Together, they cover six broad topics that are relevant to identifying potential human behavioral universals. Family and social organization. Predation pressure is thought to be the main force favoring group-living in primates, but there is great diversity in the size and structure of social groups across the primate order. Research on the behavioral ecology of primates and other animals has revealed that the distribution of males and females in space and time can be explained by sex-speci?c adaptations that are sensitive to factors that limit their ?tness: access to resources for females and access to potential mates for males.

The secrets of our genetic heritage are finally being unlocked. The massive scientific effort to sequence the human genome is in fact just the beginning of a long journey as the extraordinary genetic diversity that exists between individuals becomes clear. Work in this field is yielding profound insights into the wider implications for understanding biology, human health and history. It promises much: to understand our evolutionary origins, to define us as individuals, to predict our risk of disease and to more effectively understand, treat and prevent illness. Genetics can help us understand both rare inherited disorders and common multifactorial disease like asthma, heart disease and diabetes. Huge investments are being made and great advances have been achived, but the challenges remain daunting. This book provides an authoritative overview of this topical and very rapidly advancing field of biomedical research.
Human Genetic Diversity provides a concise, authoritative overview of human genetic diversity. It documents the insights that human genetics have brought to an understanding of human evolution and history, focusing on the implications of human genetic diversity for disease susceptibility and treatment. The book describes the genetic basis for diseases such as HIV, AIDS, Crohn's disease, asthma and type I diabetes. It also examines the emerging field of pharmacogenomics and individualized medicine.
Human genetic variation has implications across a broad range of disciplines (both biological and medical) and this text neatly consolidates work in diverse fields to highlight common themes and principles. An accessible style and the extensive use of illustrations promote its relevance to a broad audience ranging from those interested in human and population genetics to molecular biologists, evolutionary biologists, biological anthropologists and individuals working in the health sciences and clinical medicine.

In order to gain an understanding of the dynamics of human individual and average growth patterns it is essential that the right methods are selected. There are a variety of methods available to analyse individual growth patterns, to estimate variation in different growth measures in populations and to relate genetic and environmental factors to individual and average growth. This volume provides an overview of modern techniques for the assessment and collection of growth data and methods of analysis for individual and population growth data. The book contains the basic mathematical and statistical tools required to understand the concepts of the methods under discussion and worked examples of analyses, but it is neither a mathematical treatise, nor a recipe book for growth data analysis. Aimed at junior and senior researchers involved in the analysis of human growth data, this book will be an essential reference for anthropologists, auxologists and paediatricians.

The transition in anthropological and biomedical research methods over the past 50 years, from anthropometric and craniometric measurements to large-scale microarray genetic studies has resulted in continued revision of opinions and ideas relating to the factors and forces that drive human variation.

Human Variation: From the Laboratory to the Field brings together the contributions of 22 scientists working in four continents to identify and address challenges imposed by variability. It reviews the way we examine and analyze human variation, paying specific attention to genetics, growth and development, and physiology. In presenting new evidence and findings, it also discusses current developments in methodology and analytical techniques, detailing both field and laboratory approaches, and looking at how the two perspectives complement each other.

In bridging that gap between laboratory trials and studies of the human in context, this book covers a number of interesting research areas including ?

• Human adaptation to natural and artificial light, including variations in circadian photosensitivity and effects of light on GI activity
• Cold tolerance and lifestyle in modern society
• Genetics of body weight and obesity
• Human adaptability to emotional and intellectual mental stresses
• Geography, migration, climate, and environmental plasticity as contributors to human variation
• Impact of natural environmental stressors including pollution on physiological and morphological processes

This book is the latest volume in a series of works from the Society for the Study of Human Biology (SSHB), which for half a century has advanced and promoted research in the biology of human populations in all of its branches including human viability, genetics, human adaptability, and ecology, and evolution. It holds two scientific meetings a year. This volume represents work presented during its most recent gathering.

This major volume of original essays maps the place of emotion in human nature, through a discussion of the relation between consciousness and body; by analysing the importance of emotion for human agency by pointing to the ways in which practical rationality may be enhanced, as well as hindered, by emotions; and by exploring questions of value in making sense of emotions at a political, ethical and personal level. Leading researchers in the field reflect on the nature of human feelings, how and why we understand what other people feel, and the way in which our values become involved in specific emotional phenomena, such as guilt, fear, shame, amusement, or love. This collection addresses important questions in the philosophy of mind and comments on the implications of research in biology, cognitive psychology, psychoanalysis, and narrative theory for the philosophical understanding of emotions.

Bestselling author David Ewing Duncan takes the ultimate high-tech medical exam, investigating the future impact of what's hidden deep inside all of us
David Ewing Duncan takes ""guinea pig"" journalism to the cutting edge of science, building on award-winning articles he wrote for Wired and National Geographic, in which he was tested for hundreds of chemicals and genes associated with disease, emotions, and other traits. Expanding on these tests, he examines his genes, environment, brain, and body, exploring what they reveal about his and his family's future health, traits, and ancestry, as well as the profound impact of this new self-knowledge on what it means to be human.
David Ewing Duncan (San Francisco, CA) is the Chief Correspondent of public radio's Biotech Nation and a frequent commentator on NPR's Morning Edition. He is a contributing editor to Portfolio, Discover, and Wired and a columnist for Portfolio. His books include the international bestseller Calendar: Humanity's Epic Struggle to Determine a True and Accurate Year (978-0-380-79324-2). He is a former special producer and correspondent for ABC's Nightline, and appears regularly on CNN and programs such as Today and Good Morning America.

Human Population Dynamics introduces theoretical frameworks and methodologies from different traditional disciplines to demonstrate how changes in human population structure can be addressed from several different academic perspectives. The book contains contributions from world-renowned researchers in demography, social and biological anthropology, genetics, biology, sociology, ecology, history and human geography. In particular, the contributors emphasize the lability of many population structures and boundaries, as viewed from their area of expertise.

The human genetic make-up of Latin America is a reflection of successive waves of colonization and immigration. There have been few works dealing with the biology of human populations at a continental scale, and while much data is available on the genetics of Latin American populations, most information remains scattered throughout the literature. This volume examines Latin American human populations in relation to their origins, environment, history, demography and genetics, drawing on aspects of nutrition, physiology, and morphology for an integrated and multidisciplinary approach. The result is a fascinating account of a people characterized by a turbulent history, marked heterogeneity, and unique genetic traits.

This book spans two million years of human evolution and explores the impact of economics on human evolution and natural history. The theory of evolution by natural selection has always relied in part on progress in areas of science outside of biology. By applying economic principles at the borderlines of biology, Haim Ofek shows how some of the outstanding issues in human evolution, such as the increase in human brain size and the expansion of the environmental niche humans occupied, can be answered. He identifies distinct economic forces at work, beginning with the transition from the feed-as-you-go strategy of primates, through hunter-gathering and the domestication of fire to the development of agriculture. This highly readable book will inform and intrigue general readers and those in fields such as evolutionary biology and psychology, economics, and anthropology.

Biology of Aging, Second Edition presents the biological principles that have led to a new understanding of the causes of aging and describes how these basic principles help one to understand the human experience of biological aging, longevity, and age-related disease. Intended for undergraduate biology students, it describes how the rate of biological aging is measured; explores the mechanisms underlying cellular aging; discusses the genetic pathways that affect longevity in various organisms; outlines the normal age-related changes and the functional decline that occurs in physiological systems over the lifespan; and considers the implications of modulating the rate of aging and longevity. The book also includes end-of-chapter discussion questions to help students assess their knowledge of the material. Roger McDonald received his Ph.D. from the University of Southern California and is Professor Emeritus in the Department of Nutrition at the University of California, Davis. Dr. McDonald's research focused on mechanisms of cellular aging and the interaction between nutrition and aging. His research addressed two key topics in the field: the relationship between dietary restriction and lifespan, and the effect of aging on circadian rhythms and hypothalamic regulation. You can contact Dr. McDonald at [email protected]. Related Titles Ahmad, S. I., ed. Aging: Exploring a Complex Phenomenon (ISBN 978-1-1381-9697-1) Moody, H. R. & J. Sasser. Gerontology: The Basics (ISBN 978-1-1387-7582-4) Timiras, P. S. Physiological Basis of Aging and Geriatrics (ISBN 978-0-8493-7305-3)

"Man the Hunted" argues that primates, including the earliest members of the human family, have evolved as the prey of any number of predators, including wild cats and dogs, hyenas, snakes, crocodiles, and even birds. The authors' studies of predators on monkeys and apes are supplemented here with the observations of naturalists in the field and revealing interpretations of the fossil record. Eyewitness accounts of the "man the hunted" drama being played out even now give vivid evidence of its prehistoric significance.

This provocative view of human evolution suggests that countless adaptations that have allowed our species to survive--from larger brains to speech--stem from a considerably more vulnerable position on the food chain than we might like to imagine. The myth of early humans as fearless hunters dominating the earth obscures our origins as just one of many species that had to be cautious, depend on other group members, communicate danger, and come to terms with being merely one cog in the complex cycle of life.

The expanded edition includes a new chapter that describes the ever-increasing evidence of predation on humans and other primates and claims that the earliest humans were neither hunters nor even the accomplished scavengers that many authorities have claimed.

Contents

Foreword by Ian Tattersall

1. Just Another Item on the Menu
2. Debunking "Man the Hunter"
3. Who's Eating Whom?
4. Lions and Tigers and Bears, Oh My!
5. Coursing Hyenas and Hungry Dogs
6. Missionary Position
7. Terror from the Sky
8. We Weren't Just Waiting Around to be Eaten!
9. Gentle Savage or Bloodthirsty Brute?
10. Man the Hunted
11. The Final Word

Analyses of the ecology, biology and society of past and present-day hunter-gatherers are at the core of this interdisciplinary volume. Since the seminal work of Man the Hunter in 1968, new research in these three areas has become increasingly specialized, and the lines of communication among academic disciplines have all but broken down. This volume aims to reestablish an interdisciplinary debate, presenting critical issues commanding an ongoing interest in hunter-gatherer research, covering the evolution and history, demography, biology, technology, social organization, art, and language of diverse groups. As a reference text, this book will be useful to scholars and students of social anthropology, archaeology, biological anthropology, and human sciences.

The threat of unstoppable plagues, such as AIDS and Ebola, is always with us. In Europe, the most devastating plagues were those from the Black Death pandemic in the 1300s to the Great Plague of London in 1665. For the past 100 years it has been accepted that Yersinia pestis, the infective agent of bubonic plague, was responsible for these epidemics. This book combines modern concepts of epidemiology and molecular biology with computer-modeling. Applying these concepts to the analysis of historical epidemics, the authors show that they were not, in fact, outbreaks of bubonic plague. Biology of Plagues offers a completely new interdisciplinary interpretation of the plagues of Europe, and establishes them within a geographical, historical, and demographic framework. This fascinating detective work will be of interest to readers in the social and biological sciences, and lessons learned will underline the implications of historical plagues for modern-day epidemiology.

"Soul, Psyche, Brain" is a collection of essays that address the relationships between neuroscience, religion and human nature. The book highlights some startling new developments in neuroscience that have many people rethinking spirituality, the mind-body connection, and cognition in general. "Soul, Psyche, Brain" explores questions like: What are the neurological effects of meditation and prayer? How does the mind develop psychological and spiritual self-awareness? And what are the practical implications of brain-mind science for religious faith and moral reasoning?

As we enter the twenty-first century, a number of medical, environmental, and social changes have profoundly affected human reproduction. This book discusses some of the more dramatic changes in an accessible manner, illustrating the ways in which human biology and culture can affect fertility. It provides a unique interdisciplinary perspective on the subject. Topics of discussion include medical technological advances that equip us with potential cures for many causes of infertility; diseases, such as AIDS, that have a devastating impact on the reproductive and social lives of humans; increasing industrialization and the development of fabricated materials that pollute our environment in unforeseen ways with possibly devastating effects on human health and fertility; and social revolutions that profoundly alter human relationships, such as nonmarital unions between heterosexual couples, same-sex relationships, and adoption and surrogacy.

Fat is a vital yet hugely under-rated organ.

Fat has become a dirty word, but we know so little about how it really works. In Fat, expert doctors and obesity researchers Dr Mariëtte Boon and Professor Liesbeth van Rossum present the ground-breaking research which explodes many of the myths and prejudices surrounding body fat and will make us completely rethink our relationship with it.

Making use of the cutting-edge research in this specialist field, this fascinating and entertaining book will explain how fat generates important hormones, communicates with our brains and is, indeed, essential for staying alive. Informative yet accessible, Fat: The Secret Organ is important reading, not only for people who have struggled with their weight, but for everybody who is serious about their health.

Our Human Story is a guide to our fossil relatives, from what may be the earliest hominins such as Sahelanthropus, dating back six to seven million years, through to our own species, Homo sapiens. Over the past 25 years there has been an explosion of species' names in the story of human evolution, due both to new discoveries and to a growing understanding of the diversity that existed in the past. Drawing on this new information, as well as their own considerable expertise and practical experience, Louise Humphrey and Chris Stringer explain in clear and accessible terms what each of the key species represents and how it contributes to our knowledge of human evolution.

Fat is not just excess weight, but actually a dynamic, smart, and self-sustaining organ that influences everything from aging and immunity to mood and fertility. With cutting-edge research and riveting case studies-including the story of a girl who had no fat, and that of a young woman who couldn't stop eating-Dr. Sylvia Tara reveals the surprising science behind our most misunderstood body part and its incredible ability to defend itself. Exploring the unexpected ways viruses, hormones, sleep, and genetics impact fat, Tara uncovers the true secret to losing weight: working with your fat, not against it.

In our fast-paced world of technology and conveniences, the biological origins of women's inequality can be forgotten. This book offers a richer understanding of gender inequality by explaining a key cause-women's reproductive and lactation patterns. Until about 1900, infants nursed every fifteen minutes on average for two years because very frequent suckling prevented pregnancy. The practice evolved because it maximized infant survival. If a forager child was born before its older sibling could take part in the daily food search, the older one died. This practice persisted until the modern era because until after the discovery of the germ theory of disease, human milk was the only food certain to be unspoiled. Lactation patterns excluded women from the activities that led to political leadership. During the twentieth century the ancient mode declined and women entered the labor market en masse. Joan Huber challenges feminists toward a richer understanding of biological origins of inequality-knowledge that can help women achieve greater equality today.

'From your brain to your fingertips, you emerge from her book entertained and with a deeper understanding of yourself' Richard Dawkins 'A masterful account of why our bodies are the way they are . . . this book really shines . . . Roberts's lightness of touch is joyous, and celebratory' Observer 'Witty, personal and above all informed by passion and deep knowledge, this is the story of you, not just from conception onwards but from the millions of years of evolution that have shaped the way we are today' Adam Rutherford ***SHORTLISTED FOR THE WELLCOME BOOK PRIZE*** Alice Roberts takes you on the most incredible journey, revealing your path from a single cell to a complex embryo to a living, breathing, thinking person. It's a story that connects us with our distant ancestors and an extraordinary, unlikely chain of events that shaped human development and left a mark on all of us. Alice Roberts uses the latest research to uncover the evolutionary history hidden in all of us, from the secrets found only in our embryos and genes - including why as embroyos we have what look like gills - to those visible in your anatomy. This is a tale of discovery, exploring why and how we have developed as we have. This is your story, told as never before.

From the author of the award-winning bestseller The Content of Our Character comes a new essay collection that tells the untold story behind the polarized racial politics in America today. In A Dream Deferred Shelby Steele argues that a second betrayal of black freedom in the United States--the first one being segregation--emerged from the civil rights era when the country was overtaken by a powerful impulse to redeem itself from racial shame. According to Steele,1960s liberalism had as its first and all-consuming goal the expiation of America guilt rather than the careful development of true equality between the races. This "culture of preference" betrayed America's best principles in order to give whites and America institutions an iconography of racial virtue they could use against the stigma of racial shame. In four densely argued essays, Steele takes on the familiar questions of affirmative action, multiculturalism, diversity, Afro-centrism, group preferences, victimization--and what he deems to be the atavistic powers of race, ethnicity, and gender, the original causes of oppression. A Dream Deferred is an honest, courageous look at the perplexing dilemma of race and democracy in the United States--and what we might do to resolve it.

As widespread social transformations have been paralleled by gains in health and life expectancy through public health and other improvements, a variety of new obstacles to health have emerged. Lifestyle-related, behaviorally mediated changes in rates of chronic disease are the most prevalent of these new challenges. This book examines the relationship between human biology and human society, and how behavior, hormones, and health intersect. There is both scientific interest and practical urgency behind the ideas and findings presented here, as the need for a socioecological view of function and well-being has become more apparent. This book documents an emerging understanding of how hormones create the linkage between behavior or social life and health.

With the advent of the Human Genome Project there have been many claims for the genetic origins of complex human behavior including insanity, criminality, and intelligence. But what does it really mean to call something "genetic"? This is the fundamental question that Sahotra Sarkar's book addresses. This important book clarifies the meaning of the term "genetic," shows how molecular studies have affected genetics, and provides the philosophical background necessary to understand the debates over the Human Genome Project. It will be of particular interest to professionals and students in the philosophy of science, the history of science, and the social studies of science, medicine, and technology.