"Why We Sleep is an important and fascinating book...Walker taught me a lot about this basic activity that every person on Earth needs. I suspect his book will do the same for you." --Bill Gates A New York Times bestseller and international sensation, this "stimulating and important book" (Financial Times) is a fascinating dive into the purpose and power of slumber. Sleep is one of the most important but least understood aspects of our life, wellness, and longevity. Until very recently, science had no answer to the question of why we sleep, or what good it served, or why we suffer such devastating health consequences when we don't sleep. Compared to the other basic drives in life--eating, drinking, and reproducing--the purpose of sleep remained elusive. An explosion of scientific discoveries in the last twenty years has shed new light on this fundamental aspect of our lives. Now, preeminent neuroscientist and sleep expert Matthew Walker gives us a new understanding of the vital importance of sleep and dreaming. Within the brain, sleep enriches our ability to learn, memorize, and make logical decisions. It recalibrates our emotions, restocks our immune system, fine-tunes our metabolism, and regulates our appetite. Dreaming mollifies painful memories and creates a virtual reality space in which the brain melds past and present knowledge to inspire creativity. Walker answers important questions about sleep: how do caffeine and alcohol affect sleep? What really happens during REM sleep? Why do our sleep patterns change across a lifetime? How do common sleep aids affect us and can they do long-term damage? Charting cutting-edge scientific breakthroughs, and synthesizing decades of research and clinical practice, Walker explains how we can harness sleep to improve learning, mood, and energy levels; regulate hormones; prevent cancer, Alzheimer's, and diabetes; slow the effects of aging; increase longevity; enhance the education and lifespan of our children, and boost the efficiency, success, and productivity of our businesses. Clear-eyed, fascinating, and accessible, Why We Sleep is a crucial and illuminating book.

This proceedings volume describes the current state of research dealing with biological shape analysis. The quantitative analysis of the shape of biological organisms represents a challenge that has now seen breakthroughs with new methodologies such as elliptical Fourier analysis, quantitative trait loci analysis (QTLs), thin plate splines, etc. The volume also illustrates the diversity of disciplines that are actively involved in the characterization and analysis of the biological shape. Some of the papers deal with the need to relate the underlying genome responsible for the actual observed characteristics of form. Moreover, many of the papers focus on the relationship of the shape to the processes that determine the biological form, an issue of major continuing concern in biology.This volume brings together for the second time practitioners from a variety of disciplines who have been concerned with the necessity of applying new methods to the analysis of biological shape. Previous methodologies based on the conventional metrical approach (distances, angles and ratios), have not been able to adequately capture - in quantitative terms - the subtleties and complexities of biological form due to its irregularity. This volume represents an initial attempt to quantitatively characterize the biological form in both two- and three-dimensions, as it is actually perceived.There is no volume available that deals with the subject matter of these Proceedings. The papers represent, as in the first proceedings, a unique look at: (1) new methodologies developed and used quantitatively describe the biological form; (2) the need to relate the observed biological shape to the underlying processes that determine the shape; and (3) the tremendous diversity of disciplines actively involved in the characterization and analysis of biological shapes. These range from physical anthropology, anatomy, genetics, botany, entomology, forensics, to applied mathematics, etc.

Spotting a face in a crowd is so easy, you take it for granted. But how you do it is one of science's great mysteries. Vision is involved in nearly a third of everything a brain does and explaining how it works reveals more than just how we see. It also tells us how the brain processes information - how it perceives, learns and remembers. In We Know It When We See It, pioneering neuroscientist Richard Masland covers everything from what happens when light hits your retina, to the increasingly sophisticated nerve nets that turn that light into knowledge, to what a computer algorithm must be able to do before it can truly be called 'intelligent'. It is a profound yet accessible investigation into how our bodies make sense of the world.

Contents:
1. Bodily Openings; 2. 'Corporeographers'; 3. Pregnant Bodies in Public Places; 4. Men's Bodies and Bathrooms; 5. Managing Managerial Bodies; 6. Some Thoughts on Close(t) Spaces; Appendix, Notes, Bibliography

After a deconstruction of the past and present conditions of scientific understanding of human sex-ratio at birth, the authors are proposing a reconstruction of the dynamics of the phenomenon based on stochastics. This is an attempt in renewing our links with the oldest traditions of scholarly thinking, but too a kind of well-tempered reflexivity in today's work of objectivization. Appendixes get to the reader the first expression of a trend of the sex ratio at birth to adjust towards balance between the sexes by Condorcet in 1793-1794; a comparison of passages that Darwin devoted in 1871 and 1874 to similar issues; and a sociological attempt of Halbwachs published in 1933.

This volume is the proceedings of the International Conference on Inhibin, Activin: Recent Advances and Future Views held in Tokushima, Japan from November 9-10, 1996. The Internationally recognized faculty present the latest research in the exploration of inhibin, activin and follistatin mechanisms of action.

In "Body Parts," E. Richard Gold examines whether the body and materials derived from it -- such as human organs and DNA -- should be thought of as market commodities and subject to property law. Analyzing a series of court decisions concerning property rights, Gold explores whether the language and assumptions of property law can help society determine who has rights to human biological materials.

Gold observes that the commercial opportunities unleashed by advances in biotechnology present a challenge to the ways that society has traditionally valued the human body and human health. In a balanced discussion of both commercial and individual perspectives, Gold asserts the need to understand human biological materials within the context of human values, rather than economic interests.

This perceptive book will be welcomed by scholars and other professionals engaged in questions regarding bioethics, applied ethics, the philosophy of value, and property and intellectual property rights. Given the international aspects of both intellectual property law and biotechnology, this book will be of interest throughout the world and especially valuable in common-law (most English-speaking) countries.

With the use of crack on the rise in American cities, there is more need than ever to understand the biological, environmental, and social factors behind cocaine addiction, as well as the pharmacological properties of cocaine that make it such an addictive drug. The Neurobiology of Cocaine Addiction helps clinicians and researchers analyze research findings and their relevance to the clinical treatment of cocaine dependency. To do this, it looks at the whole spectrum of cocaine use, from trends in cocaine-involved deaths, hospital emergencies, arrests, and treatment admissions to the specific impact the drug has on brain function. The book reports on important findings from positron emission tomography (PET) and a "binge" pattern cocaine administration mode. This will enable you to improve your understanding of how cocaine alters the pleasure/reward system of the brain and creates new instinctual needs that displace the inherent instinctual needs of hunger and sex.By reading The Neurobiology of Cocaine Addiction, you will sharpen your knowledge of the basic actions of cocaine, the factors related to daily cocaine use, the neurobiological basis of addictive diseases, and drug-induced alterations in normal physiology. You will also learn about: the coexistence of cocaine and heroin addiction cocaine's disruption of the endogenous opioid system QEEG and how it can play a potentially useful role in drug development and planning hypotheses of sensitization in the pathophysiology of cocaine dependence factors that predict daily cocaine use among patients in a methadone maintenance program abnormalities in brain function that persist for up to six months after last cocaine use patterns of cocaine use the importance of prospective data analysis and the limitations of a self-selective study groupClinicians, researchers, psychiatrists, and other professionals in chemical dependency and narcotics rehabilitation will turn the last page of The Neurobiology of Cocaine Addiction with a better understanding of cocaine's addictive qualities and the characteristics of the individuals who become addicted to it. You will see what headway has been made in research at some of the nation's top laboratories, but you will also see what remains to be done. Hopefully, you will find where you can make a contribution either at the practical level, the research level, or both.

How did an obscure academic idea pave the way to the Holocaust within just fifty years? Why does eugenics still loom large in the 21st century, despite its genocidal past? Did eugenics work? Could it work? Or was it always a pseudoscientific fantasy? Throughout history, people have sought to reduce suffering, eliminate disease and enhance desirable qualities in their children. In the Victorian era eugenics, a full-blooded attempt to impose control over unruly biology, began to grow among the powerful and quickly spread to dozens of countries around the world. But these ideas are not merely historical: today, with new gene editing techniques, conversations are happening about tinkering with the DNA of our unborn children to make them smarter, fitter, stronger. Deeply steeped in contemporary genetics, CONTROL offers a vital account of one of the defining - and most destructive - ideas of the twentieth century.

Conceived at a time when biological research on aggression and violence was drawn into controversy because of sociopolitical questions about its study, this volume provides an up-to-date account of recent biological studies performed -- mostly on humans. A group of scientists recognized the importance of freedom of inquiry and deemed it vital to address the most promising biological research in the field. The focus on biological mechanisms is not meant to imply that biological variables are paramount as a determinant of violence. Rather, biological variables operate in conjunction with other variables contributing to aggression or violence, and a complete understanding of this phenomenon requires consideration of all influences bearing on it.
This book will familiarize readers with the rapidly growing and increasingly significant body of knowledge on the biological bases of human antisocial, aggressive, and violent behaviors. The editors concentrated on biological influences that support the basic physiological and biochemical processes of the brain and did not cover those biological influences that impact on the health of the individual such as head injury, pregnancy and birth complications, diet, and exposure to lead and other toxins. They focused on biological influences to illuminate their role in the complex behavioral phenomenon of violence.
Three different approaches to the biological study of human antisocial, aggressive, and violent behaviors are represented -- genetic, neurobiological, and biosocial. Representing each of these three approaches, individual chapters from investigators in psychobiology, biological psychiatry, and basic-clinical neurosciences address the most recent experimental findings, methods, theory, and common misconceptions in the biological study of aggression and violence. The areas of primary focus are behavior and molecular genetics, neurochemistry and hormones, neuroimaging, psychophysiology and developmental psychobiology. Generally speaking, investigators following these different approaches have experience in different scientific backgrounds, select different methods, generate different analyses, employ different conceptual definitions for some of the same terms, and assume a different philosophical stance in attempting to explain violence. Nevertheless, all are united in their efforts to understand the biological underpinnings of violence. This book then assumes a comprehensive approach wherein different levels of analysis and different approaches inform each other. It is clear from the studies reported that aggression and violence are multidetermined phenomena and understanding them requires an interdisciplinary approach spanning economic, sociopolitical, psychological, sociological, and criminological as well as biomedical considerations. Nature (biology) and nurture (experience, context) are fundamentally inseparable in explaining aggression and violence; biology may affect experience or context, but experience or context also influences biology. Both need to be studied in a search for explanations of this phenomena.

1) Classic anatomical atlases 2) Detailed labeling of the earliest phases of prenatal neorological development 3) Appeals to neuroanatomists, developmental biologists and clinical practioners. 4) Persistent relevance - brain development is not going to change.

It has become received wisdom that our world is doomed, that we live in the End of Days. Bleak predictions by psychics and scientists alike portend extreme weather, droughts, famines and floods that will overtake humanity within the century, or sooner. If not global warming, then supervolcanoes, meteoric impacts, nuclear war, bioterrorism, or natural plagues will get us. But whatever happens, Michael Hanlon believes that humankind will go on...and on. The shape of things to come will be strange, and somewhat terrifying, but will very likely seem banal to the people who inhabit it in the future. Humankind may be thrown back to the Stone Age on hundreds of occasions and may come close to extinction. But recovery will follow--each time more rapidly than the last. The world of 10,000 years hence, let alone 100,000,000 years hence, will be strange and almost unrecognizable. But no matter how battered and re-born, it will still be "our" world, populated by "us" through eternity.

This book discusses the European Union's approach to governance reform in its development assistance relationships with various groups of developing countries. A group of expert authors outline the general features of the position on governance taken by the EU, which is currently the major multilateral donor of development assistance, and discuss the implementation of EU policies in a set of cases: the group of African, Caribbean and Pacific (ACP) states, the New Partnership for Africa's Development (NEPAD), Southeastern Europe, Central Asia, the Euro-Mediterranean, Latin America and fragile states. The contributions to the book argue that the EU's position on governance reform, particularly since the adoption of the European Consensus on Development in 2005, has had distinctly neoliberal overtones. The EU's governance-related strategies have been instrumental to deepening market-based reform in aid-receiving countries. Policies on state-building adopted by the EU reflect mainly the interests of and ideas embraced by the EU and its member states. To an important extent, the rhetoric accompanying EU policies does not match with the political and social dynamics inherent in governance structures on the ground in many of its aid-recipient partner countries. This book was published as a special issue of Third World Quarterly.

Key Features 1) Detailed summary of every recorded variation and anomaly for each muscle in the human body 2) Information on comparative anatomy of each muscle (e.g., how each human muscle may appear in our closest living relatives, the apes). 3) Schematic illustrations of the variations and anomalies for easy visualization 4) Comprehensive literature review resulting in the most accurate prevalence information for each variation and anomaly 5) Diverse group of co-authors from various academic and cultural backgrounds

Until the publication of Charles Darwin's On the Origin of Species, the prevailing theory on 'the species question' was that humans were made up of five separate species, created at different times and in different places. This view - known as the 'polygenic theory' - was particularly favoured by naturalists of the early nineteenth-century 'American School' as it provided a scientific justification for slavery. Darwin's Origin demolished this view. This work fills a gap in recent studies on the history of race and science. Focusing on both the classification systems of human variety and the development of science as the arbiter of truth, Brown looks at the rise of the emerging sciences of life and society - biology and sociology - as well as the debate surrounding slavery and abolition.

Originally published in 1976, this introduction to hearing was intended to provide a sufficient introduction to each of several subareas of hearing so that the serious student can read the more advanced treatments with greater appreciation and understanding. It was intended for upper graduate and graduate students. It assumes some mathematical sophistication - calculus for example, but there is some review of more basic concepts, such as logarithms. There is also a brief treatment of the necessary material from the different disciplines - physics, physiology, psychology, anatomy and mathematics - that a student of hearing will need to know.

Harry Baker and Rosalind Ridley have done an admirable job in assem bling this collection of articles that describe the methodology frequently used to study a group of CNS illnesses often referred to as the "prion diseases." Research on prions and the disorders that they cause has progressed relatively rapidly over the last decade since the discovery of the prion protein (PrP) that allowed the application of modem molecular biological and genetic tools. The power of these techniques is awesome and their use in deciphering the once mysterious prion diseases has brought a wealth of new information. Although prions are unprecedented pathogens, appearing to consist only of PrPSc molecules, the diseases that they cause are no less remarkable. The prion diseases in animals include scrapie of sheep and goats as well as "mad cow" disease or bovine spongiform encephalopathy (BSE). In the United King dom, the epidemic of BSE has heightened public awareness of this previously obscure group of diseases such that any work in the field is likely to stir up interest in the media and become a subject of public debate. It has been diffi cult for British investigators to work on prion diseases without being involved in these controversies. As such, several chapters have been included that deal with political and social issues surrounding prion diseases. The human prion diseases present an equally fascinating saga in which these CNS degenerations present as genetic, sporadic, and infectious illnesses."

These two volumes demonstrate the role of cellular mechanisms in the production of the many specialized traits defining primates. By exploring gene activity transforming into evolutionary change through the work of cellular mechanisms, the goal is to encourage others to adopt evolutionary cell biology as an approach to the genotype-phenotype map of the diversification of primates, human variation, and human evolution. Contributors highlight how genetic analysis, visualization of cells and tissues, and merging Evo-Devo with evolutionary cell biology combine to answer questions central to understanding the human and primate evolution. Key Features Explores the developmental basis of characteristics that define the primate lineage Documents cellular mechanisms associated with everything from skin and eneregetics to the brain and communication. Chapters by a team of leading international researchers

A "courageous, compassionate, and rigorous every-person's guide" (Christina Bethell, PhD, Johns Hopkins Bloomberg School of Public Health) that shows the link between Adverse Childhood Experiences (ACEs) and diseases, and how to cope and heal from these emotional traumas. Your biography becomes your biology. The emotional trauma we suffer as children not only shapes our emotional lives as adults, but it also affects our physical health, longevity, and overall well-being. Scientists now know on a bio-chemical level exactly how parents' chronic fights, divorce, death in the family, being bullied or hazed, and growing up with a hypercritical, alcoholic, or mentally ill parent can leave permanent, physical "fingerprints" on our brains. When children encounter sudden or chronic adversity, stress hormones cause powerful changes in the body, altering the body's chemistry. The developing immune system and brain react to this chemical barrage by permanently resetting children's stress response to "high," which in turn can have a devastating impact on their mental and physical health as they grow up. Donna Jackson Nakazawa shares stories from people who have recognized and overcome their adverse experiences, shows why some children are more immune to stress than others, and explains why women are at particular risk. "Groundbreaking" (Tara Brach, PhD, author of Radical Acceptance) in its research, inspiring in its clarity, Childhood Disrupted explains how you can reset your biology-and help your loved ones find ways to heal. "A truly important gift of understanding-illuminates the heartbreaking costs of childhood trauma and like good medicine offers the promising science of healing and prevention" (Jack Kornfield, author of A Path With Heart).

Offers an original and fertile way to integrate spiritual and scientific views of human evolution. It offers a new and refreshing alternative to the way we think about our origins: random mutation (mechanistic neo-Darwinism), Genesis (God did it all personally), and Intelligent Design (God personally does what we can't otherwise account for). The result is an invigorating perspective on how our best qualities -- our capacity for love, our appreciation of beauty, our altruistic capability, our creativity and intelligence -- have come into being and evolved. How we think about our origin matters: if we think we are machines living among other machines, we will act accordingly. By showing evolution as a creative and intelligent process with its own inherent logic, THE ORIGIN OF HUMAN NATURE resolves the dilemma of how to have, at the same time, both truth and ethics. Instead of starting in an imagined remote and 'uncertain past' and moving to the present, this book starts at the certain and 'immediate present' and works back. That consciousness, creativity, and intelligence exist is certain. The question is: how can these have evolved? Dr Albert Low has made a study of human nature throughout his life. To write this book he draws on his prolonged meditations on creativity and the human condition, his years of providing psychological and spiritual counseling, and a wide-ranging knowledge of Western psychology, philosophy, and science.

"Fascinating and exhilarating-Sean B. Carroll at his very best."-Bill Bryson, author of The Body: A Guide for Occupants From acclaimed writer and biologist Sean B. Carroll, a rollicking, awe-inspiring story of the surprising power of chance in our lives and the world Why is the world the way it is? How did we get here? Does everything happen for a reason or are some things left to chance? Philosophers and theologians have pondered these questions for millennia, but startling scientific discoveries over the past half century are revealing that we live in a world driven by chance. A Series of Fortunate Events tells the story of the awesome power of chance and how it is the surprising source of all the beauty and diversity in the living world. Like every other species, we humans are here by accident. But it is shocking just how many things-any of which might never have occurred-had to happen in certain ways for any of us to exist. From an extremely improbable asteroid impact, to the wild gyrations of the Ice Age, to invisible accidents in our parents' gonads, we are all here through an astonishing series of fortunate events. And chance continues to reign every day over the razor-thin line between our life and death. This is a relatively small book about a really big idea. It is also a spirited tale. Drawing inspiration from Monty Python, Kurt Vonnegut, and other great thinkers, and crafted by one of today's most accomplished science storytellers, A Series of Fortunate Events is an irresistibly entertaining and thought-provoking account of one of the most important but least appreciated facts of life.

Microbiota are a promising and fascinating subject in biology because they integrate the microbial communities in humans, animals, plants, and the environment. In humans, microbiota are associated with the gut, skin, and genital, oral, and respiratory organs. The plant microbial community is referred to as "holobiont," and it is influential in the maintenance and health of plants, which themselves play a role in animal health and the environment. The contents of Microbiome-Host Interactions cover all areas as well as new research trends in the fields of plant, animal, human, and environmental microbiome interactions. The book covers microbiota in polar soil environments, in health and disease, in Caenorhabditis elegans, and in agroecosystems, as well as in rice root and actinorhizal root nodules, speleothems, and marine shallow-water hydrothermal vents. Moreover, this book provides comprehensive accounts of advanced next-generation DNA sequencing, metagenomic techniques, high-throughput 16S rRNA sequencing, and understanding nucleic acid sequence data from fungal, algal, viral, bacterial, cyanobacterial, actinobacterial, and archaeal communities using QIIME software (Quantitative Insights into Microbial Ecology). FEATURES Summarizes recent insight in microbiota and host interactions in distinct habitats, including Antarctic, hydrothermal vents, speleothems, oral, skin, gut, feces, reproductive tract, soil, root, root nodules, forests, and mangroves Illustrates the high-throughput amplicon sequencing, computational techniques involved in the microbiota analysis, downstream analysis and visualization, and multivariate analysis commonly used for microbiome analysis Describes probiotics and prebiotics in the composition of the gut microbiota, skin microbiome impact in dermatologic disease prevention, and microbial communities in the reproductive tract of humans and animals Presents information in a reachable way for students, teachers, researchers, microbiologists, computational biologists, and other professionals who are interested in strengthening or enlarging their knowledge about microbiome analysis with next-generation DNA sequencing in the different branches of the sciences