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Taking a critical look at some of the recent controls over human life, health, and death, Fletcher draws a vivid picture of contemporary biological needs and ethical responsibility. Genetic engineering, foetal research, abortion, suicide, human experimentation, infanticide, and euthanasia are some of the issues explored in it.

This series presents reviews covering all aspects of haemodynamics and haemorheology. Topics covered include the complexities of microcirculation, the rheology of blood and blood vessels, and the mechanics of blood flow in arteries and veins. The contributions aim to reflect the advances being made in experimental techniques and instrumentation for laboratory and clinical measurements and in numerical and mathematical modelling. Emphasis is placed on the scientific and engineering principles involved, but particular attention is also given to the clinical significance of this area of research. Topics covered by this volume include viscoelastic properties of blood and blood analogues; blood flow through narrow tubes; and numerical modelling of blood flow.

This book covers the main aspects of biological rhythms. It focuses on the evolution and basic features of the biorhythms in organisms, deals with the circadian system at the genetic, molecular and cellular levels, and describes the mechanisms involved in the perception and light entrainment of the biological clock in vertebrates and invertebrates. The most important features of the biological clock are summarized on the level of whole organisms, from fish to mammals, and long-term (seasonal) rhythms in plants and higher vertebrates are discussed. Finally, the book concentrates on short-term rhythms, the significance of having a biological clock system in animals living in extreme (Arctic) environments, and on the diversity of circadian responses to melatonin, one of the key endocrine elements involved in the regulation of biological rhythms.

Advances in sensing, signal processing, and computer technology during the past half century have stimulated numerous attempts to design general-purpose ma chines that see. These attempts have met with at best modest success and more typically outright failure. The difficulties encountered in building working com puter vision systems based on state-of-the-art techniques came as a surprise. Perhaps the most frustrating aspect of the problem is that machine vision sys tems cannot deal with numerous visual tasks that humans perform rapidly and effortlessly. In reaction to this perceived discrepancy in performance, various researchers (notably Marr, 1982) suggested that the design of machine-vision systems should be based on principles drawn from the study of biological systems. This "neuro morphic" or "anthropomorphic" approach has proven fruitful: the use of pyramid (multiresolution) image representation methods in image compression is one ex ample of a successful application based on principles primarily derived from the study of biological vision systems. It is still the case, however, that the perfor of computer vision systems falls far short of that of the natural systems mance they are intended to mimic, suggesting that it is time to look even more closely at the remaining differences between artificial and biological vision systems."

The aim of this text is to provide reviews and monographs on topics involving molecular similarity, ranging from the fundamental physical properties underlying molecular behaviour to applications in industrially important fields such as pharmaceutical drug design and molecular engineering. The editors hope that this series will encourage new ideas and approaches, help to systematize the rapidly accumulating new chemical information, and make chemistry better understood and better applied.

Human factors, also known as human engineering or human factors engineering, is the application of behavioral and biological sciences to the design of machines and human-machine systems. Automation refers to the mechanization and integration of the sensing of environmental variables, data processing and decision making and mechanical action. This book deals with all the issues involved in human-automation systems from design to control and performance of both humans and machines.

This volume of Progress in Inflammation Research is a unique compilation of work performed by a wide spectrum of investigators from different medical disciplines. It is fascinating that dietary alterations of fatty acid intake can result in a range of salutory changes in a great variety of medical conditions. Most of the good scien tific work which has led to these observations has been performed over just the last two decades. This is of course not a very long time in the context of the history of the human species. Recently performed analysis of fat intake from paleolithic times has indicated that our hunter-gatherer ancestors consumed as much cholesterol as modern Western man, but strikingly less saturated fatty acid and more polyunsatu rates, including n-3 fatty acids. Wild game has the terrestrial source of n-3 incorpo rated in its fat since browsing animals derive 18:3n-3 (alpha-linolenic acid) natural ly from leafy plants. There is, however, little opportunity for modern Western man to get n-3 fatty acids from the diet if one does not consume fish. Modern agribusiness provides ani mal feeds high in n-6 fatty acids, mostly derived from linoleic acid (18:2n-6) in corn feed. Therefore, grazing animals have no access to alternative fatty acids in either feed or grasses, the latter containing little or none of these potentially beneficial highly polyunsaturated fatty acids."

Understanding the Mysteries of Practical Human Biology for Non-Scientists provides students with an accessible overview of the structure and function of the human body. The text provides highly practical information students can use to make healthful choices, better understand news and media about nutrition, medications, medical devices, and procedures, and grow their knowledge about genetic or infectious diseases. The text features coverage of bones, muscles, nerves and hormones, heart and blood vessels, lungs, digestive organs, and kidneys, with emphasis on how they all work together for balance and health. Students also learn about male and female anatomy in the context of reproduction. Readers explore aspects of life, such as coordination of the musculoskeletal, nervous, and endocrine systems, and various responses of the human immune system. Providing readers with foundational knowledge that can help them make informed decisions related to their lifestyle and personal health, Understanding the Mysteries of Practical Human Biology for Non-Scientists is ideal for elective science courses for non-majors, as well as introductory anatomy and physiology courses.

The Proceedings of the Fourth International Metallothionein Meeting (MT-97) feature the latest research on metallothionein. The book covers a broad range of topics which provide important information for both basic and clinical investigators. The selected 94 articles in this book are written by the leading scientists in the field around the world. This is an increasingly important, multi-disciplinary area of study that has benefitted from recent advances in concepts and methodologies from other fields.

F. Macfarlane Burnet I have been an interested onlooker for many years at research on the biology of trace elements, particularly in its bearing on the pas toral and agricultural importance of copper, zinc, cobalt, and mo lybdenum deficiencies in the soil of various parts of Australia. More recently I have developed a rather more specific interest in the role of zinc, particularly in relation to the dominance of zinc metalloenzymes in the processes of DNA replication and repair, and its possible significance for human pathology. One area of special significance is the striking effect of zinc deficiency in the mother in producing congenital abnormalities in the fetus. The fact that several chapters in the present work are concerned with this and other aspects of zinc deficiency is, I fancy, the editors jus tification for inviting me to write this foreword. In reading several of the chpaters before publication, my main impression was of the great potential importance of the topic of trace metal biology in both its negative and positive aspects-the effects of deficiency of essential elements and the toxicity of such pollutants of the modern world as lead or mercury mainly as or ganic compounds."

Advances in fossil studies relating to the origin of Homo sapiens have strengthened the hypothesis that our direct ancestors originated on the African continent. Most researchers also agree that the time when prehumans diverged from the last common ancestor was in the early part of the Late Miocene epoch.

Focus must now shift from determining the times and places of hominid origins to clarifying hominid evolutionary problems, such as the selective factors and acquisition processes of hominid bipedalism. In March of 2003, researchers from Africa, Europe, Japan and the United States convened in Kyoto for a symposium on Human Origins and Environmental Backgrounds, an interdisciplinary effort to consider these evolutionary puzzles, to report current research and to exchange thoughts towards better understanding the relationship among environmental changes, adaptive mechanisms and human origins. This book is the result of that symposium, and includes a diverse and unique set of papers on topics such as hominid evolution, dispersal and morphology, and the origins of bipedalism.

A New York Times bestseller and a Book of the Year for the Evening Standard and The Times.

Is getting a little less comfortable the key to living a happier, healthier life?

When journalist Scott Carney came across a picture of a man in his fifties sitting on a glacier in just his underwear, he assumed it must be a hoax. Dutch guru Wim Hof claimed he could control his body temperature using his mind and teach others to do the same. Sceptical, Carney signed up to Hof’s one-week course, not realising that it would be the start of a four-year journey to unlock his own evolutionary potential.

From hyperventilating in a Polish farmhouse to underwater weight training in California, and eventually climbing Mt Kilimanjaro wearing just shorts and running shoes, Carney travelled the world testing out unorthodox methods of body transformation and discovering the science behind them.

In What Doesn’t Kill Us he explains how getting a little less comfortable can help us to unlock our lost evolutionary strength.

This book challenges the assumption that morphological data are inherently unsuitable for phylogeny reconstruction, argues that both molecular and morphological phylogenies should play a major role in systematics, and provides the most comprehensive review of the comparative anatomy, homologies and evolution of the head, neck, pectoral and upper limb muscles of primates. Chapters 1 and 2 provide an introduction to the main aims and methodology of the book. Chapters 3 and 4 and Appendices I and II present the data obtained from dissections of the head, neck, pectoral and upper limb muscles of representative members of all the major primate groups including modern humans, and compare these data with the information available in the literature. Appendices I and II provide detailed textual (attachments, innervation, function, variations and synonyms) and visual (high quality photographs) information about each muscle for the primate taxa included in the cladistic study of Chapter 3, thus providing the first comprehensive and up to date overview of the comparative anatomy of the head, neck, pectoral and upper limb muscles of primates. The most parsimonious tree obtained from the cladistic analysis of 166 head, neck, pectoral and upper limb muscle characters in 18 primate genera, and in representatives of the Scandentia, Dermoptera and Rodentia, is fully congruent with the evolutionary molecular tree of Primates, thus supporting the idea that muscle characters are particularly useful to infer phylogenies. The combined anatomical materials provided in this book point out that modern humans have fewer head, neck, pectoral and upper limb muscles than most other living primates, but are consistent with the proposal that facial and vocal communication and specialized thumb movements have probably played an important role in recent human evolution. This book will be of interest to primatologists, comparative anatomists, functional morphologists, zoologists, physical anthropologists, and systematicians, as well as to medical students, physicians and researchers interested in understanding the origin, evolution, homology and variations of the muscles of modern humans. Contains 132 color plates.

The book that you hold in your hands is the second in a series. The two titles in the series are the following: Genetic Influences on Human Fertility and Sexuality: Theoretical and Empirical Contributions from the Biological and Behavior Sciences Edited by Joseph Lee Rodgers, David C. Rowe, & Warren B. Miller Published by Kluwer Academic Press, 2000 The Biodemography of Human Reproduction and Fertility Edited by Joseph Lee Rodgers & Hans-Peter Kohler Published by Kluwer Academic Press, 2002 The series has published chapters by researchers who study human fertility, from a particular perspective: Biodemography. We welcome your interest and participation in this developing subfield. Or, perhaps, biodemography may be better referred to as a "superfield. " Because biodemography so naturally crosses interdisciplinary boundaries, and because its application draws together researchers from disparate disciplines, it may well be more appropriate to consider that biodemography subsumes a number of other disciplines, rather than the other way around. In this preface, we will describe our own efforts and those of many others to promote and develop the study of human fertility, using methods, models, and theories from both biological and demographic domains. In December, 1997, 25 participants from three different countries gathered in Tucson, Arizona for a small conference with the title "Genetic Influences on Fertility-Related Processes. " That conference represented a fascinating blending of research from two apparently separate domains.

Authoritative investigators active in the discovery, development, and application of biological anti-infective agents concisely review their use and potential in preventing and treating human disease. Focusing on biotherapeutic entities that have been tested in controlled studies, the prominent experts illuminate the scientific underpinnings of their therapeutic power, assess their possible risks in the treatment of infectious diseases, and outline the research needed to better define their effectiveness. In addition, they also consider how biotherapeutic agents may be genetically engineered for maximum intestinal and vaginal production of bioactive substances in vivo. Biotherapeutic Agents and Infectious Diseases brings together all the evidence needed to understand and capitalize on the considerable promise of this significant new class of biotherapeutic entities.

The Liver in Biology and Disease was conceived as a sequel in the series "Principles of Medical Biology," whose general aim continues to be the integration of human biology and molecular cell biology into modern molecular medicine. It is a volume molded by the Information Revolution which few will deny has forced the teaching faculties in our medical schools to curtail and prune the teaching load and focus on fundamentals and principles. With this intention in mind, a volume of this nature takes into account the close dependence of progress in the medical sciences on bioinformatics (gene and protein analysis) or more precisely, computational biology and of course, the Internet. In general, it follows the pattern of its predecessors.
*Chapters are illustrated with numerous figures and references are current
*Clear, concise and accurate text about a large number of liver diseases
*Describes the liver's histology, biochemistry, and pathology in molecular terms

What happened along the evolutionary trail that made humans so unique? In his accessible style, Michael Gazzaniga pinpoints the change that made us thinking, sentient humans different from our predecessors. He explores what makes human brains special, the importance of language and art in defining the human condition, the nature of human consciousness, and even artificial intelligence.

Etienne-Emile Baulieu, the discoverer of neurosteroids, and a panel of distinguished scientists and clinical researchers exhaustively and critically review all facets of neurosteroids involved in behavior, stress, memory, depression, anxiety, aging of the brain, and neurodegenerative diseases. These contributors illuminate the role of neurosteroids in brain development and plasticity and detail their neuromodulatory influence on GABAA, ionotropic glutamate receptors, acetylcholine receptors, sigma receptors, and calcium channels. Clearly pointing the way toward novel pharmaceutical agents that may be of significant therapeutic value, particularly with regard to aging mental functions, Neurosteroids: A New Regulatory Function in the Nervous System offers neurobiologists, psychiatrists, neurosurgeons, pharmacologists, and geriatricians the first comprehensive, state-of-the-art review of these important bioactive molecules.

Ranging from Aristotle to twentieth-century gynaecology, contributions to this volume trace the semiotics of menstruation from magical act to evolutionary deficiency. The result is the first comprehensive historical study of how menstruation has been understood within various cultural traditions, with reference to political and social institutions, and medical and religious practices. Includes a guide for scholars on bibliographical and archival sources for the study of menstruation.