Leading scholars take stock of Darwin's ideas about human evolution in the light of modern science In 1871, Charles Darwin published The Descent of Man, a companion to Origin of Species in which he attempted to explain human evolution, a topic he called "the highest and most interesting problem for the naturalist." A Most Interesting Problem brings together twelve world-class scholars and science communicators to investigate what Darwin got right-and what he got wrong-about the origin, history, and biological variation of humans. Edited by Jeremy DeSilva and with an introduction by acclaimed Darwin biographer Janet Browne, A Most Interesting Problem draws on the latest discoveries in fields such as genetics, paleontology, bioarchaeology, anthropology, and primatology. This compelling and accessible book tackles the very subjects Darwin explores in Descent, including the evidence for human evolution, our place in the family tree, the origins of civilization, human races, and sex differences. A Most Interesting Problem is a testament to how scientific ideas are tested and how evidence helps to structure our narratives about human origins, showing how some of Darwin's ideas have withstood more than a century of scrutiny while others have not. A Most Interesting Problem features contributions by Janet Browne, Jeremy DeSilva, Holly Dunsworth, Agustin Fuentes, Ann Gibbons, Yohannes Haile-Selassie, Brian Hare, John Hawks, Suzana Herculano-Houzel, Kristina Killgrove, Alice Roberts, and Michael J. Ryan.

The topic of stem cells has a high profile in the media. We've made important advances in our scientific understanding, but despite this the clinical applications of stem cells are still in their infancy and most real stem cell therapy carried out today is some form of bone marrow transplantation. At the same time, a scandalous spread of unproven stem cell treatments by private clinics represents a serious problem, with treatments being offered which are backed by limited scientific rationale, and which are at best ineffective, and at worse harmful. This Very Short Introduction introduces stem cells, exploring what they are, and what scientists do with them. Introducing the different types of stem cells, Jonathan Slack explains how they can be used to treat diseases such as retinal degeneration, diabetes, Parkinson's disease, heart disease, and spinal trauma. He also discusses the important technique of bone marrow transplantation and some other types of current stem cell therapy, used for the treatment of blindness and of severe burns. Slack warns against fake stem cell treatments and discusses how to distinguish real from fake treatments. He also describes the latest scientific progress in the field, and looks forward to what we can expect to happen in the next few years Very Short Introductions: Brilliant, Sharp, Inspiring ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.

'A new approach to mental disorder. Randolph Nesse's insightful book suggests that conditions such as anxiety and depression have a clear evolutionary purpose ... This intriguing book turns some age-old questions about the human condition upside down' Tim Adams, Observer One of the world's most respected psychiatrists provides a much-needed new evolutionary framework for making sense of mental illness With his classic book Why We Get Sick, Randolph Nesse established the field of evolutionary medicine. Now he returns with a book that transforms our understanding of mental disorders by exploring a fundamentally new question. Instead of asking why certain people suffer from mental illness, Nesse asks why natural selection has left us with fragile minds at all. Drawing on revealing stories from his own clinical practice and insights from evolutionary biology, Nesse shows how negative emotions are useful in certain situations, yet can become excessive. Anxiety protects us from harm in the face of danger, but false alarms are inevitable. Low mood prevents us from wasting effort in pursuit of unreachable goals, but it often escalates into pathological depression. Other mental disorders, such as addiction and anorexia, result from the mismatch between modern environments and our ancient human past. Taken together, these insights and many more help to explain the pervasiveness of human suffering, and show us new paths for relieving it. Good Reasons for Bad Feelings will fascinate anyone who wonders how our minds can be so powerful, yet so fragile, and how love and goodness came to exist in organisms shaped to maximize Darwinian fitness.

Population Biology of Vector-Borne Diseases is the first comprehensive survey of this rapidly developing field. The chapter topics provide an up-to-date presentation of classical concepts, reviews of emerging trends, synthesis of existing knowledge, and a prospective agenda for future research. The contributions offer authoritative and international perspectives from leading thinkers in the field. The dynamics of vector-borne diseases are far more intrinsically ecological compared with their directly transmitted equivalents. The environmental dependence of ectotherm vectors means that vector-borne pathogens are acutely sensitive to changing environmental conditions. Although perennially important vector-borne diseases such as malaria and dengue have deeply informed our understanding of vector-borne diseases, recent emerging viruses such as West Nile virus, Chikungunya virus, and Zika virus have generated new scientific questions and practical problems. The study of vector-borne disease has been a particularly rich source of ecological questions, while ecological theory has provided the conceptual tools for thinking about their evolution, transmission, and spatial extent. Population Biology of Vector-Borne Diseases is an advanced textbook suitable for graduate level students taking courses in vector biology, population ecology, evolutionary ecology, disease ecology, medical entomology, viral ecology/evolution, and parasitology, as well as providing a key reference for researchers across these fields.

'Amy's book is everything I should have learned at school. It is a reminder to empower ourselves, in a world that still sadly lacks so much knowledge around women's health, by getting to know our own bodies more intimately - with the help of technology built by women' Emma Gannon 'Moody is a fascinating and friendly guide for you to understand you better.' Melissa Hemsley 'Knowledge is power and this book equips you with the power to unlock potential and happiness.' Poppy Jamie, author of Happy Not Perfect There is a secret inside you which, once you understand it fully, has the capacity to unlock untold potential. Once you learn the science of your hormones, you will be able to harness it forever. Hormones were something Amy Thomson, founder and CEO of leading women's health app and tech service Moody, never paid attention to, until one day her periods stopped and what had been an inconvenience each month became a barometer for her body's health and mental happiness. When she discovered that her hormonal burnout was driven by stress, she quit her job and focused on trying to understand how her body worked, to establish why and how she had pushed herself too far. In this guide, Amy shares the research and science behind how our hormones work for twenty-first-century survival, how understanding them can help you build better and healthier routines, and why the systems and cycles inside us are an invisible but powerful force. With insights from nutritionists, gynaecologists, endocrinologists, personal trainers and others, Moody provides a holistic and practical blueprint for understanding your hormones and optimising your life around them. Praise for Moody 'As a woman, medical doctor and scientist I found Moody hugely illuminating' Dr Tara Swart

In classical scholarship, the presence of legal language in love poetry is commonly interpreted as absurd and incongruous. Ovid's legalisms have been described as frivolous, humorous, and ornamental. Law and Love in Ovid challenges this wide-spread, but ill-informed view. Legal discourse in Latin love poetry is not incidental, but fundamental. Inspired by recent work in the interdisciplinary field of law and literature, Ioannis Ziogas argues that the Roman elegiac poets point to love as the site of law's emergence. The Latin elegiac poets may say 'make love, not law', but in order to make love, they have to make law. Drawing on Agamben, Foucault, and Butler, Law and Love in Ovid explores the juridico-discursive nature of Ovid's love poetry, constructions of sovereignty, imperialism, authority, biopolitics, and the ways in which poetic diction has the force of law. The book is methodologically ambitious, combining legal theory with historically informed closed readings of numerous primary sources. Ziogas aims to restore Ovid to his rightful position in the history of legal humanism. The Roman poet draws on a long tradition that goes back to Hesiod and Solon, in which poetic justice is pitted against corrupt rulers. Ovid's amatory jurisprudence is examined vis-a-vis Paul's letter to the Romans. The juridical nature of Ovid's poetry lies at the heart of his reception in the Middle Ages, from Boccaccio's Decameron to Forcadel's Cupido iurisperitus. The current trend to simultaneously study and marginalize legal discourse in Ovid is a modern construction that Law and Love in Ovid aims to demolish.

Metabolism, behaviour, sleep, mood swings, the immune system, fighting, fleeing, puberty and sex: these are just a few of the things our bodies control with hormones. Armed with a healthy dose of wit and curiosity, medical journalist Randi Hutter Epstein takes us on a journey through the unusual history of these potent chemicals from a basement filled with jarred nineteenth-century brains to a twenty-first-century hormone clinic in Los Angeles. Brimming with fascinating anecdotes, illuminating new medical research and humorous details, Aroused introduces the leading scientists who made life-changing discoveries about the hormone imbalances that ail us, as well as the charlatans who used those discoveries to peddle false remedies.

There's a silent epidemic in western civilization, and it is right under our noses. Our jaws are getting smaller and our teeth crooked and crowded, creating not only aesthetic challenges but also difficulties with breathing. Modern orthodontics has persuaded us that braces and oral devices can correct these problems. While teeth can certainly be straightened, what about the underlying causes of this rapid shift in oral evolution and the health risks posed by obstructed airways? Sandra Kahn and Paul R. Ehrlich, a pioneering orthodontist and a world-renowned evolutionist, respectively, present the biological, dietary, and cultural changes that have driven us toward this major health challenge. They propose simple adjustments that can alleviate this developing crisis, as well as a major alternative to orthodontics that promises more significant long-term relief. Jaws will change your life. Every parent should read this book.

A clear and straightforward explanation of genetics in this new edition of the popular 101 series. Our genetic makeup determines so much about who we are, and what we pass on to our children-from eye color, to height, to health, and even our longevity. Genetics 101 breaks down the science of how genes are inherited and passed from parents to offspring, what DNA is and how it works, how your DNA affects your health, and how you can use your personal genomics to find out more about who you are and where you come from. Whether you're looking for a better scientific understanding of genetics, or looking into your own DNA, Genetics 101 is your go-to source to discover more about both yourself and your ancestry.

SHORTLISTED FOR THE WELLCOME BOOK PRIZE 2017 Your body is teeming with tens of trillions of microbes. It's an entire world, a colony full of life. In other words, you contain multitudes. These microscopic companions sculpt our organs, protect us from diseases, guide our behaviour, and bombard us with their genes. They also hold the key to understanding all life on earth. In I Contain Multitudes, Ed Yong opens our eyes and invites us to marvel at ourselves and other animals in a new light, less as individuals and more as thriving ecosystems. We learn the invisible and wondrous science behind the corals that construct mighty reefs and the squid that create their own light shows. We see how bacteria can alter our response to cancer-fighting drugs, tune our immune system, influence our evolution, and even modify our genetic make-up. And we meet the scientists who are manipulating these microscopic partners to our advantage. In a million tiny ways, I Contain Multitudes will radically change the way you think about the natural world, and the way you see yourself.

Written primarily for 16-19-year-old students, this primer covers the anatomy and physiology of the key organ systems in the human body. It provides students with an overview of the anatomical details and physiological principles of the organ systems of the body and discusses the pathophysiology of common diseases that can affect them. It also considers how surgical approaches can be used to manage commonly presenting diseases of these systems. In addition, the primer explores surgery and anaesthesia both in a historical and contemporary context, examining how surgical and anaesthetic approaches have advanced over the centuries and how they continue to evolve to make surgery safer and more effective. The primer aims to extend students' knowledge and inspire them to take their school-level learning further. It explores topics that are familiar from the curriculum and also introduces new ideas, giving students a first taste of the study of biology beyond school-level, and demonstrating how concepts frequently encountered at school are relevant to and applied in current research. This is the ideal text to support students who are considering making the transition from studying biology at school to university. Digital formats and resources The book is available for students and institutions to purchase in a variety of formats, and is supported by online resources: * The e-book offers a mobile experience and convenient access along with functionality tools, navigation features, and links that offer extra learning support: www.oxfordtextbooks.co.uk/ebooks * Online resources include multiple choice questions for students to check their understanding, and, for registered adopters, figures and tables from the book

More than a history, From Cells to Organisms delves into the nature of scientific practice, showing that results are interpreted not only through the lens of a microscope, but also through the lens of particular ideas and prior philosophical convictions. Before the twentieth century, heredity and development were considered complementary aspects of the fundamental problem of generation, but later they became distinct disciplines with the rise of genetics. Focusing on how cell theory shaped investigations of development, this book explores evolution, vitalism, the role of the nucleus, and the concept of biological individuality. Building upon the work of Thomas Huxley, an important early critic of cell theory, and more recent research from biologists such as Daniel Mazia, From Cells to Organisms covers ongoing debates around cell theory and uses case studies to examine the nature of scientific practice, the role of prestige, and the dynamics of theory change.

A 'kluge' is an engineering term for a makeshift solution, an inelegant construction that somehow works. This is Gary Marcus's analogy for the way the human mind has evolved. Arguing against a whole tradition that praises our human minds as the most perfect result of evolution, Marcus shows how imperfect and ill-adapted our brains really are. They have had to adapt from the environment of our early hominid origins to a complex world in which our penchant for short-term satisfactions is literally fatal. We are prone to rages, addictions and other habits that limit our capacity for rational action in every sphere, from food to politics. A breathtaking, witty and revolutionary book.

Biology of Aging, Second Edition presents the biological principles that have led to a new understanding of the causes of aging and describes how these basic principles help one to understand the human experience of biological aging, longevity, and age-related disease. Intended for undergraduate biology students, it describes how the rate of biological aging is measured; explores the mechanisms underlying cellular aging; discusses the genetic pathways that affect longevity in various organisms; outlines the normal age-related changes and the functional decline that occurs in physiological systems over the lifespan; and considers the implications of modulating the rate of aging and longevity. The book also includes end-of-chapter discussion questions to help students assess their knowledge of the material. Roger McDonald received his Ph.D. from the University of Southern California and is Professor Emeritus in the Department of Nutrition at the University of California, Davis. Dr. McDonald's research focused on mechanisms of cellular aging and the interaction between nutrition and aging. His research addressed two key topics in the field: the relationship between dietary restriction and lifespan, and the effect of aging on circadian rhythms and hypothalamic regulation. You can contact Dr. McDonald at [email protected]. Related Titles Ahmad, S. I., ed. Aging: Exploring a Complex Phenomenon (ISBN 978-1-1381-9697-1) Moody, H. R. & J. Sasser. Gerontology: The Basics (ISBN 978-1-1387-7582-4) Timiras, P. S. Physiological Basis of Aging and Geriatrics (ISBN 978-0-8493-7305-3)

For courses in human biology This package includes MasteringBiology (TM). Explore Human Biology in Relation to Current Issues, in the Text and Online. Through his teaching, his textbook, and his online blog, award-winning teacher Michael D. Johnson sparks interest in human biology by connecting basic biology to real-world issues that are relevant to students' lives. Using a storytelling approach and extensive online support, Human Biology: Concepts and Current Issues Eighth Edition not only demystifies how the human body works but also drives students to become a better, more discerning consumer of health and science information. Each chapter opens with Johnson's popular "Current Issues" essays, and within each chapter, "BlogInFocus" references direct readers to his frequently-updated blog for breaking human biology-related news. This package includes MasteringBiology, an online homework, tutorial, and assessment product proven to improve results by helping students quickly master concepts. Students benefit from opportunities to practice basic science literacy skills, using interactive resources that create engaging learning experiences. Effective activities in MasteringBiology help students further visualize and understand complex biological processes. MasteringBiology should only be purchased when required by an instructor. Please be sure you have the correct ISBN and Course ID. Instructors, contact your Pearson representative for more information.

Joseph L. Graves Jr traces the development of biological thought about human genetic diversity. Greek philosophy, social Darwinism, New World colonialism, the eugenics movement, intelligence testing biases and racial health fallacies are just a few of the topics he addresses. Graves argues that racism has persisted in our society because adequate scientific reasoning has not entered into the equation. He cautions us to think critically about scientific findings that have historically been misused in controversies over racial differences in intelligence, criminal behaviour, disease predisposition and other traits. This book aims to demonstrate that America cannot truly address its racial problems until people understand the empirical evidence that proves separate human races do not exist. With the biological basis for race removed, racism becomes an ideology, one that can and must be erased.

Die Bedeutung der Hand liegt gewissermassen auf der Hand: Ohne dieses Wunderwerk an Prazision und Empfindsamkeit, an Kraft und Sanftheit, an Ausdrucksfahigkeit und Steuerbarkeit auszukommen, ware fur die meisten von uns kaum vorstellbar. So selbstverstandlich ist uns ihr Gebrauch und sind uns ihre Fahigkeiten, dass wir selten hinterfragen, wie die Hand eigentlich genau funktioniert und wo uberall in unserer Kultur, unserer Sprache und unserem sozialen Miteinander sie ihre Spuren hinterlassen hat. Das "Hand-Buch" geht diesen Fragen nach. Renommierte Autoren spannen dabei einen Bogen, der von der evolutionaren Entwicklung der Greifhand bis zum technischen Design von Roboterhanden, vom engen Zusammenhang von Hand und Gehirn bis zu den vielfaltigen Verbindungen zwischen Hand und Sprache, von musikalischen Fingerfertigkeiten bis zum Handlesen reicht. Biologie, Medizin und Philosophie reichen sich in diesem Buch die Hande, und die Faszination fur die Hand wird durch das handfeste Wissen, das es vermittelt, nur noch grosser. Zu den Autoren des Bandes zahlen renommierte Wissenschaftler aus verschiedenen natur- und geisteswissenschaftlichen Disziplinen, unter anderem Niels Birbaumer (Tubingen, Biopsychologie), E. Altenmuller (Hannover, Musikphysiologie), Helge Ritter (Bielefeld, Neuroinformatik), Bruno Preilowski (Tubingen, Hemispharenforschung), Friedhart Klix (Berlin, Evolutionspsychologie) und Peter Janich (Marburg, Philosophie)."

THE NEW YORK TIMES BESTSELLER FROM THE WINNER OF THE 2021 PULITZER PRIZE Your body is teeming with tens of trillions of microbes. It's an entire world, a colony full of life. In other words, you contain multitudes. They sculpt our organs, protect us from diseases, guide our behaviour, and bombard us with their genes. They also hold the key to understanding all life on earth. In I Contain Multitudes, Ed Yong opens our eyes and invites us to marvel at ourselves and other animals in a new light, less as individuals and more as thriving ecosystems. You'll never think about your mind, body or preferences in the same way again. 'Super-interesting... He just keeps imparting one surprising, fascinating insight after the next. I Contain Multitudes is science journalism at its best' Bill Gates SHORTLISTED FOR THE WELLCOME BOOK PRIZE 2017 SHORTLISTED FOR THE ROYAL SOCIETY SCIENCE BOOK PRIZE 2017

In anaesthetist Dr Kevin Fong's television programmes he has often demonstrated the impact of extremes on the human body by using his own body as a 'guinea pig'. So Dr Fong is well placed to share his experience of the sheer audacity of medical practice at extreme physiological limits, where human life is balanced on a knife edge. Through gripping accounts of extraordinary events and pioneering medicine, Dr Fong explores how our body responds when tested by the extremes of heat and cold, vacuum and altitude, age and disease. He shows how science, technology and medicine have taken what was once lethal in the world and made it survivable. This is not only a book about medicine, but also about exploration in its broadest sense - and about how, by probing the very limits of our biology, we may ultimately return with a better appreciation of how our bodies work, of what life is, and what it means to be human.

Muscle tissue powers every heartbeat, blink, jog, jump and goosebump. It is the force behind the most critical bodily functions, including digestion and childbirth, as well as extreme feats of athleticism. We can mould our muscles with exercise and observe the results. In this lively, lucid book, orthopedic surgeon Roy A. Meals takes us on a wide-ranging journey through anatomy, biology, history and health to unlock the mysteries of our muscles. He breaks down the three different types of muscle—smooth, skeletal and cardiac—and explores major advancements in medicine and fitness, including cutting-edge gene-editing research and the science behind popular muscle conditioning strategies. Along the way, he offers insight into the changing aesthetic and cultural conception of muscle, from Michelangelo’s David to present-day bodybuilders, and shares fascinating examples of strange muscular maladies and their treatment. Brimming with fun facts and infectious enthusiasm, Muscle sheds light on the astonishing, essential tissue that moves us through life.

Love is a little word with a universe of meanings and has engaged people's interest throughout human history. The need to give and receive love lies deep within human nature. Philosophers, poets, theologians, sociologists, and scientists have all attempted to explain its exact origin, but is it an evolutionary adaptation, or a social construct? Walsh discusses that the nature of and need for love has biological origins. He draws upon Darwin's sexual selection theory to define the perceptions of love by infants through the process of experience-dependent brain wiring. He observes that mother love makes a child capable of loving and that father love makes a child feel worthy of love. He appraises the origin and purpose of romantic love in his discussions on sexual reproduction by looking at chemical and neurological responses to love and the influence of love on one's physical and mental health. With frequent quotes from literary masters like Shakespeare to orient one's scientific and humanistic understanding of love, Walsh goes on to explore various styles of romantic love, including monogamy, promiscuity, bartering love, and betrayed love; the effects of a skewed sex ratio on dating and mating practices; and the age-old quest for a perfect society populated by perfect people obeying the biblical command to "love one another."