The nanotechnology revolution that will transform human health and longevity Nano Comes to Life opens a window onto the nanoscale-the infinitesimal realm of proteins and DNA where physics and cellular and molecular biology meet-and introduces readers to the rapidly evolving nanotechnologies that are allowing us to manipulate the very building blocks of life. Sonia Contera gives an insider's perspective on this new frontier, revealing how nanotechnology enables a new kind of multidisciplinary science that is poised to give us control over our own biology, our health, and our lives. Drawing on her perspective as one of today's leading researchers in the field, Contera describes the exciting ways in which nanotechnology makes it possible to understand, interact with, and manipulate biology-such as by designing and building artificial structures and even machines at the nanoscale using DNA, proteins, and other biological molecules as materials. In turn, nanotechnology is revolutionizing medicine in ways that will have profound effects on our health and longevity, from nanoscale machines that can target individual cancer cells and deliver drugs more effectively, to nanoantibiotics that can fight resistant bacteria, to the engineering of tissues and organs for research, drug discovery, and transplantation. The future will bring about the continued fusion of nanotechnology with biology, physics, medicine, and cutting-edge fields like robotics and artificial intelligence, ushering us into a new "transmaterial era." As we contemplate the power, advantages, and risks of accessing and manipulating our own biology, Contera offers insight and hope that we may all share in the benefits of this revolutionary research.

This two-day symposium in the annual Society for the Study of Human Biology Symposium Series covers a wide spectrum of growth physiology, and presents a state-of-the-art review of human auxology, from factors affecting cellular growth, through nutritional factors affecting the growth of the infant, to endocrine and other factors affecting the growth of the child before and after adolescence. Wiith contributions from some of the leading workers in the various fields, the book starts with a consideration of the effects of experimental removal of parts of mouse embryos on final body size and the part played by local tissue interactions in the specification of limb segments in insects. Discussion of the growth-promoting actions of the somatomedins in foetal, post-natal and brain growth follow, leading to two chapters on Man, dealing with energy requirements and body composition in infants, and the endocrine control of body size and sexual development during puberty.

"Coyne's knowledge of evolutionary biology is prodigious, his deployment of it as masterful as his touch is light." -Richard Dawkins
In the current debate about creationism and intelligent design, there is an element of the controversy that is rarely mentioned-the evidence. Yet the proof of evolution by natural selection is vast, varied, and magnificent. In this succinct and accessible summary of the facts supporting the theory of natural selection, Jerry A. Coyne dispels common misunderstandings and fears about evolution and clearly confirms the scientific truth that supports this amazing process of change. Weaving together the many threads of modern work in genetics, paleontology, geology, molecular biology, and anatomy that demonstrate the "indelible stamp" of the processes first proposed by Darwin, "Why Evolution Is True" does not aim to prove creationism wrong. Rather, by using irrefutable evidence, it sets out to prove evolution right.

Signaling by calcium ions is an important regulator of muscle contraction, nerve impulses, fertilization, and numerous other cellular processes. This book explores the experimental techniques used to monitor movement of calcium ions into/out of cells and between subcellular compartments, as well as analyse its effects on the intracellular targets that mediate its effects.

Can you taste words, feel flavours as a shape, or hear colors? If so you may well have synaesthesia, a neurological condition that gives rise to a 'merging of the senses'. This Very Short Introduction describes synaesthesia's many forms, and delves into the underlying neuroscience. Explaining the scientific basis for synaesthesia, Julia Simner considers how we can measure the effects synaesthesia has on the everyday lives of people living with it. Exploring the fascinating stories of different synaesthetes' experiences of the world, she also discusses the documented links between synaesthesia, childhood development, memory, personality, and artistic creativity, and the potential limitations synaesthesia might impose. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.

Primate Sexuality provides an authoritative and comprehensive synthesis of current research on the evolution and physiological control of sexual behaviour in the primates - prosimians, monkeys, apes, and human beings. This new edition has been fully updated and greatly expanded throughout to incorporate a decade of new research findings. It maintains the depth and scientific rigour of the first edition, and includes a new chapter on human sexuality, written from a comparative perspective. It contains 2600 references, almost 400 figures and photographs, and 73 tables.

It has been remarked that if the brain were so simple we could understand it, we would be so simple we couldn't. Commencing with a brief history of neuroscience, from the ancient practice of drilling holes in the head to relieve headaches to the latest results from MRI and CT scans, this accessible guide sets out to explore exactly what we do know about the brain. Including the most up-to-date research on the cerebral processes behind a wide array of human activity - from our capacity for language to how we remember - this lively and entertaining introduction assumes no previous scientific knowledge and offers a tantalizing glimpse into man's most complex organ.

'Sacks is rightly renowned for his empathy . . . anyone with a taste for the exotic will find this beautifully written book highly engaging' - Sunday Times Always fascinated by islands, Oliver Sacks is drawn to the Pacific by reports of the tiny atoll of Pingelap, with its isolated community of islanders born totally colour-blind; and to Guam, where he investigates a puzzling paralysis endemic there for a century. Along the way, he re-encounters the beautiful, primitive island cycad trees - and these become the starting point for a meditation on time and evolution, disease and adaptation, and islands both real and metaphorical in The Island of the Colour-Blind.

In The Oxford Handbook of Language Evolution, sixty leading scholars present critical accounts of every aspect of the field. Its five parts are devoted to insights from comparative animal behavior; the biology of language evolution (anatomy, genetics, and neurology); the prehistory of language (when and why did language evolve?); the development of a linguistic species; and language creation, transmission, and change.
Research on language evolution has burgeoned over the last three decades. Interdisciplinary activity has produced fundamental advances in the understanding of language evolution and in human and primate evolution more generally. The book presents a wide-ranging summation of work in all the disciplines involved. It highlights the links in different lines of research, shows what has been achieved to date, and considers the most promising directions for future work.
The Oxford Handbook of Language Evolution will be valued by everyone interested in one of the most productive and fascinating fields in natural and cognitive science.

Primate Sexuality provides an authoritative and comprehensive synthesis of current research on the evolution and physiological control of sexual behaviour in the primates - prosimians, monkeys, apes, and human beings. This new edition has been fully updated and greatly expanded throughout to incorporate a decade of new research findings. It maintains the depth and scientific rigour of the first edition, and includes a new chapter on human sexuality, written from a comparative perspective. It contains 2600 references, almost 400 figures and photographs, and 73 tables.

As anyone who takes up a new sport quickly discovers, even basic athletic moves require high levels of coordination and control. Whether dribbling a basketball or hitting a backhand, limbs must be synchronized and bodies balanced, all with precise timing. But no matter how diligently we watch the pros or practice ourselves, the body's inner workings remain invisible. The Hidden Mechanics of Exercise reveals the microworld of the human body in motion, from the motor proteins that produce force, to the signaling molecules that activate muscles, to the enzymes that extract energy from nutrients. Christopher Gillen describes how biomolecules such as myosin, collagen, hemoglobin, and creatine kinase power our athletic movements. During exercise, these molecules dynamically morph into different shapes, causing muscles, tendons, blood, and other tissues to perform their vital functions. Gillen explores a wide array of topics, from how genetic testing may soon help athletes train more effectively, to how physiological differences between women and men influence nutrition. The Hidden Mechanics of Exercise tackles questions athletes routinely ask. What should we ingest before and during a race? How does a hard workout trigger changes in our muscles? Why does exercise make us feel good? Athletes need not become biologists to race in a triathlon or carve turns on a snowboard. But Gillen, who has run ten ultramarathons, points out that athletes wishing to improve their performance will profit from a deeper understanding of the body's molecular mechanisms.

Designed for undergraduate students, "Laboratory Manual for Exercise Physiology: Predictions, Equations, and Test Methods" offers comprehensive coverage of the basic testing procedures used in the assessment of human performance, health, and wellness. This user-friendly resource will assist students in developing the knowledge and skills to perform a wide range of tests and to critically analyze and synthesize data.

Authors Gregory Haff and Charles Dumke have assembled a text that introduces readers to testing that can be applied in a variety of professional settings. The book's 15 labs encompassing 49 activities lead students through a series of learning opportunities that explore the basics of testing and pretest screening as well as methods for evaluating flexibility, blood pressure, oxygen consumption and energy expenditure, aerobic and anaerobic fitness, lactate metabolism, muscular strength, pulmonary function, body composition, and electrocardiogram assessments.

"Laboratory Manual for Exercise Physiology" has been expertly sequenced to offer students an optimal learning experience. Organized in a logical progression, the labs build in complexity as students progress through the book and develop their knowledge base. A consistent heading structure enables students to easily follow the material and grasp the focus of the activities. Each laboratory is a complete lesson beginning with objectives, definitions of key terms, and background information that set the stage for learning. For each of the laboratory activities, students will find step-by-step instructions, making it easier for those new to the lab setting to complete the activities. Figures and photos throughout the text illustrate the key techniques. Data sheets are provided for each of the tests, allowing students to record their individual findings. Question sets found after each activity prompt students to put their lab experiences into context, and case studies help them understand the practical applications of the tests.

The manual includes many features that further support learning. Special binding allows the book to lie flat on the lab table, and perforated pages enable students to remove their completed worksheets from the manual for grading without removing content needed for future reference. A resource finder at the front of the book helps readers locate the tests and formulas they need. A web resource packaged with new texts provides additional tools that assist students in working through the lab activities. Here they will find each of the question sets--a handy way to fill in and print answers after completing a laboratory activity. Group data sheets found only in the web resource allow students to move beyond collecting individual data. They can use these group sheets to compile data from the entire class, calculate values such as mean and range, and compare their findings to the normative data discussed in the lab.

Instructors will find that "Laboratory Manual for Exercise Physiology" offers great flexibility in choosing the activities that suit the needs of their course and their students. Each lab contains multiple activities that cover distinct methods for introducing the testing concepts. The activities can be adapted to specific lab settings, available equipment, and time allotted. Equipment lists at the beginning of each activity make it easier to choose the labs that will work best in the lab facility. To further assist instructors in preparing for courses, access to an image bank features all the photos, illustrations, and tables from the text that can be inserted into tests, quizzes, handouts, and other course materials.

"Laboratory Manual for Exercise Physiology: Predictions, Equations, and Test Methods" will help students build their professional knowledge and skills. This resource will give them the hands-on practice they need to learn in order to evaluate athletes, clinical clients, and other healthy individuals.

Full of fascinating and bizarre cases of genetic mutation and irregularity, 'Mutants' is an amazing exploration of the human form in all its beautiful and unique guises. Why are most of us born with one nose, two legs, ten fingers and twenty-four ribs - and some of us not? Why do most of us stop growing in our teens - while others just keep going? Why do some us have heads of red hair - and others no hair at all? The human genome, we are told, makes us what we are. But how? Armand Marie Leroi takes us to the extremes of human mutation - from the grotesque to the beautiful, and often both at the same time - to explain how we become what we are. Through the tales of long-lived Croatian dwarves, ostrich-footed Wadoma tribesmen, sex-changing French convent girls, and many more wonders of human development, Leroi has written a brilliant narrative account of our genetic grammar and people whose bodies have revealed it.

'Pontzer's findings have huge implications for our attitudes to exercise, diet and public health' Mark Webster, Sunday Times A myth-busting tour of the body's hidden foundations from a pioneering evolutionary biologist 'Public health strategies stubbornly cling to the simplistic armchair engineer's view of metabolism, hurting efforts to combat obesity, diabetes, heart disease, cancer, and the other diseases that are most likely to kill us' Herman Pontzer's ground-breaking research has revealed how, contrary to received wisdom, exercise does not increase our metabolism. Instead, we burn calories within a very narrow range: nearly 3,000 calories per day, no matter our activity level. In this book, he draws on twenty years of cutting-edge science to take a closer look at what happens to the energy we consume. Burn explores the ways in which metabolism controls every aspect of our health - from fertility to immune function - and reveals the truth about the dynamic system that sustains us. Filled with facts and memorable anecdotes, this book will change the way you think about food, exercise and what really matters for your health.

Questions on the origins and meaning of dreams are as old as humankind, and as confounding and exciting today as when nineteenth-century scientists first attempted to unravel them. Why do we dream? Do dreams hold psychological meaning or are they merely the reflection of random brain activity? What purpose do dreams serve? When Brains Dream addresses these core questions about dreams while illuminating the most up-to-date science in the field. Written by two world-renowned sleep and dream researchers, it debunks common myths-that we only dream in REM sleep, for example-while acknowledging the mysteries that persist around both the science and experience of dreaming. Antonio Zadra and Robert Stickgold bring together state-of-the-art neuroscientific ideas and findings to propose a new and innovative model of dream function called NEXTUP-Network Exploration to Understand Possibilities. By detailing this model's workings, they help readers understand key features of several types of dreams, from prophetic dreams to nightmares and lucid dreams. When Brains Dream reveals recent discoveries about the sleeping brain, and the many ways in which dreams are psychologically and neurologically meaningful experiences; explores a host of dream-related disorders; and explains how dreams can facilitate creativity and be a source of personal insight. Making an eloquent and engaging case for why the human brain needs to dream, When Brains Dream offers compelling answers to age-old questions about the mysteries of sleep.

Our sense of smell - or olfaction as it is technically known - is our most enigmatic sense. It can conjure up memories, taking us back to very specific places and emotions, whilst powerful smells can induce strong feelings of hunger or nausea. In the animal kingdom smell can be used to find food, a mate, or a home; to sense danger; and to send and receive complex messages with other members of a species. Yet despite its fundamental importance in our mental life and in the existence of all animals, our scientific understanding of how smell works is limited. In this Very Short Introduction, Matthew Cobb describes the latest scientific research on smell in humans and other mammals, in insects, and even in fish. He looks at how smell evolved, how animals use it to navigate and communicate, and disorders of smell in humans. Understanding smell, especially its neurobiology, has proved a big challenge, but olfactory science has revealed genetic factors that determine what we can and cannot smell, and why some people like a given smell while others find it unbearable. He ends by considering future treatments for smell disorders, and speculating on the role of smell in a world of robots. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.

Humans and flies look nothing alike, yet their genetic circuits are remarkably similar. Here, Lewis I. Held, Jr compares the genetics and development of the two to review the evidence for deep homology, the biggest discovery from the emerging field of evolutionary developmental biology. Remnants of the operating system of our hypothetical common ancestor 600 million years ago are compared in chapters arranged by region of the body, from the nervous system, limbs and heart, to vision, hearing and smell. Concept maps provide a clear understanding of the complex subjects addressed, while encyclopaedic tables offer comprehensive inventories of genetic information. Written in an engaging style with a reference section listing thousands of relevant publications, this is a vital resource for scientific researchers, and graduate and undergraduate students.

'A work of exhilarating scope and relevance ... What a rare and powerful experience to feel a book in your very body' Naomi Klein 'Health is not something we can attain as individuals, for ourselves, hermetically sealed off from the world around us. An injury to one is an injury to all.' Our bodies, societies and planet are inflamed. In this boldly original book, renowned political economist Raj Patel teams up with physician Rupa Marya to illuminate the hidden relationships between human health and the profound injustices of our political and economic systems. In doing so, they offer a radical new cure: the deep medicine of decolonization. Journeying through the human body - our digestive, endocrine, circulatory, respiratory, reproductive, immune, and nervous systems - Marya and Patel show how inflammation is connected not just to the food that we eat, the air that we breathe and access to healthcare, but is also linked to the traumatic events we experience and the very model of health that doctors practice: one which takes things apart, rather than seeking to bring ideas and lived experiences together. Combining the latest scholarship on globalization and biology with the stories of patients in marginalized communities and the wisdom of Indigenous groups, Inflamed points the way toward a medicine that heals what has been divided and has the potential to transform not only our bodies but the world.

Reticulate Evolution and Humans is the first book to describe the effect of genetic exchange on the origin and evolution of our own species as well as those species with which we have and continue to interact closely, both evolutionarily and culturally. After demonstrating how genetic exchange has affected H. Sapiens, the book goes on to describe how the same processes have structured the evolution of organisms on which the human species depends for shelter, sustenance and companionship. It also considers the "dark-side" of gene transfer as it pertains to the evolution and adaptation of human disease vectors and diseases.
The development of the central thesis of this book - that reticulate evolution via introgressive hybridization and lateral gene transfer has been a pervasive factor in the evolution and cultural development of H. sapiens, its ancestors, sister taxa and associated organisms - reveals the extent of these processes across the widest of taxonomic, temporal and spatial bounds. We cannot escape the conclusion that we are constantly fed, entertained, sheltered, attacked and killed by organisms that possess mosaic genomes reflective of widespread genetic exchange during evolutionary diversification.

'Informative, powerful' VOGUE 'A fascinating and friendly guide for you to understand you better' MELISSA HEMSLEY 'Amy's book is everything I should have learned at school' EMMA GANNON Hormones were something Amy Thomson, founder and CEO of leading women's health app and tech service Moody, never paid attention to, until one day her periods stopped. When she discovered that her hormonal burnout was driven by stress, she quit her job and focused on trying to understand how our hormones can work for twenty-first-century survival. In this eye-opening guide, Thomson draws upon leading research from nutritionists, gynaecologists, endocrinologists, personal trainers and others to explain how understanding our systems and cycles can help you avoid burnouts, build better and healthier routines and optimise your life.

Written primarily for mid-to-upper level undergraduates, this primer will introduce students to topics at the forefront of the subject that are being applied to probe biological problems, or to address the most pressing issues facing society. These topics will include those that form the cornerstone of contemporary research, helping students to make the transition to active researcher. This primer provides an overview of the complex processes underpinning cancer development and progression along with a summary of cancer treatment strategies, emphasising the development of targeted molecular therapies and the opportunities they provide. It takes a contemporary and integrated approach, encompassing debates on genetics, epigenetics, and cancer addictions, and highlighting the remaining challenges and future research directions to advance the field.

Florence Schechter, creator of the world's first Vagina Museum, is here to take you on a journey towards celebrating, understanding and appreciating your vagina. And once you set off, you'll never look back. By the end of this empowering and inclusive book, you will be ready to talk about the vulva shame-free. You will discover art that admires the vulva. You will learn how our ancestors believed in the power of periods. And you will bust myths, feel confident in your body and find your Big V Energy! Because, if the word is taboo, how can you talk about your vagina's health? If you can't label the vulva, how can you fight for its rights? And if you don't know how extraordinary the vulva and vagina really are, you'll never realise the incredible power between your legs. With fascinating contributions from leading activists and experts. Suitable for ages 14+

In this book, Benoit Dubreuil explores the creation and destruction of hierarchies in human evolution. Combining the methods of archaeology, anthropology, cognitive neuroscience and primatology, he offers a natural history of hierarchies from the point of view of both cultural and biological evolution. This volume explains why dominance hierarchies typical of primate societies disappeared in the human lineage and why the emergence of large-scale societies during the Neolithic period implied increased social differentiation, the creation of status hierarchies, and, eventually, political centralisation.

Covers much of the acoustics a student needs, without mathematics or scientific background. Choice Outstanding Academic Title A survey of intervals and scales, tone pitch, loudness and time in Western music raises many questions about the hearing mechanism and throws doubt on the conventional role of harmonics. James Beament's account of how musical sounds are coded by the ear and the brain's processing units, provides answers to most of these questions. It concludes that music started with simple instruments which voices imitated, and that the need to know sound direction determined the characteristics of hearing. This book will interest students, practising musicians and music psychologists, and assumes no scientific knowledge. The late ProfessorSir JAMES BEAMENT was a distinguished scientist and musician, who taught and examined music students at Cambridge University.