Nurses should have the most up-to-date knowledge to provide accurate information and competent nursing care to patients with colorectal cancer. Swan addresses those issues in a very thorough and comprehensive manner.

Chapters on the role of the colorectal nurse specialist, epidemiology and genetics, diagnosis, investigations and different treatments make this book essential reading for any colorectal nurse specialist.

Colorectal cancer is the third most common cancer in men, and the second most common cancer in women in the UK. Colorectal Cancer is a very important book in this field. As mortality statistics continue to rise, this book addresses the issues surrounding colorectal cancer. It is vital to care for and attend to the needs of these patients.

This groundbreaking book presents a unique and practical approach to the evolving field of exercise oncology - the study of physical activity in the context of cancer prevention and control. Presenting the current state of the art, the book is sensibly divided into four thematic sections. Following an opening chapter presenting an overview and timeline of exercise oncology, the chapters comprising part I discuss primary cancer prevention, physical activity and survivorship, and the mechanisms by which these operate. Diagnosis and treatment considerations are discussed in part II, including prehabilitation, exercise during surgical recovery, infusion and radiation therapies, and treatment efficacy. Post-treatment and end-of-life care are covered in part III, including cardio-oncology, energetics and palliative care. Part IV presents behavioral, logistical and policy-making considerations, highlighting a multidisciplinary approach to exercise oncology as well as practical matters such as reimbursement and economics. Written and edited by experts in the field, Exercise Oncology will be a go-to practical resource for sports medicine clinicians, family and primary care physicians, oncologists, physical therapy and rehabilitation specialists, and all medical professionals who treat cancer patients.

Written primarily for mid-to-upper level undergraduates, this primer will introduce students to topics at the forefront of the subject that are being applied to probe biological problems, or to address the most pressing issues facing society. These topics will include those that form the cornerstone of contemporary research, helping students to make the transition to active researcher. This primer provides an overview of the complex processes underpinning cancer development and progression along with a summary of cancer treatment strategies, emphasising the development of targeted molecular therapies and the opportunities they provide. It takes a contemporary and integrated approach, encompassing debates on genetics, epigenetics, and cancer addictions, and highlighting the remaining challenges and future research directions to advance the field.

MicroRNA in Human Malignancies offers a deep overview of the role and translational significance of miRNAs in the development of cancer and other malignancies. The book establishes the foundations of the field by covering essential mechanisms and the translational potential of miRNAs in the field of oncology. Specific topics covered include invasion and metastasis, miRNAs and metabolism, and opportunities of miRNAs in therapeutics. Chapters on diseases include content on disease-related pathophysiology, as well as diagnostic, prognostic and predictive value. This book is an essential reference for students entering the field, as well as researchers and investigators.

'A wonderful book about wonderful books and mothers and sons and the enduring braid between them.' - Mitch Albom, author of Tuesdays With Morrie 'a true meditation on what books can do.' - Edmund de Waal, author of The Hare with Amber Eyes Mary Anne Schwalbe is waiting for her chemotherapy treatments when Will casually asks her what she's reading. The conversation they have grows into tradition: soon they are reading the same books so they can have something to talk about in the hospital waiting room. Their choices range from classic (Howards End) to popular (The Girl with the Dragon Tattoo), from fantastic (The Hobbit) to spiritual (Jon Kabat-Zinn), with many more in between. We hear their passion for reading and their love for each other in their intimate and searching discussions. The End of Your Life Book Club is a profoundly moving testament to the unconditional love between a child and parent, and the power of reading in our lives.

This volume gathers the leading research on antibody-drug conjugates and immunotoxins. Following a rigorous overview, the volume delves into focused sections on all aspects of ADCs and ITs from clinical development through to targeted therapeutic applications and the latest technologies.

In the prime of life, a wife, mother, and businesswoman, Paula Black, heard the dreaded words: "Its cancer". Doctors gave her three to six months to live. With her husband Dale's help, they tirelessly researched every conventional and alternative cancer treatment available. They discovered God-given methods that treat the whole person and the root causes of disease. Paula eventually succeeded without chemotherapy or radiation. Her advanced-stage cancer was gone. She got her life back. Using this book as your complete guide, you can do what she did -- easily, painlessly, at low cost, and at home. Never fear cancer again!

This major reference work is the most comprehensive resource on oncologic critical care. The text reviews all significant aspects of oncologic ICU practices, with a particular focus on challenges encountered in the diagnosis and management of the critically ill cancer patient population. Comprised of over 140 chapters, the text explores such topics as the organization and management of an oncologic ICU, diseases and complications encountered in the oncologic ICU, multidisciplinary care, surgical care, transfusion medicine, special patient populations, critical care procedures, ethics, pain management, and palliative care. Written by worldwide experts in the field, Oncologic Critical Care is a valuable resource for intensivists, advance practice providers, nurses, and other healthcare providers, that will help close significant knowledge and educational gaps within the realm of medical care for critically ill cancer patients.

The fourth edition of this well-received book offers a comprehensive update on recent developments and trends in the clinical and scientific applications of multislice computed tomography. Following an initial section on the most significant current technical aspects and issues, detailed information is provided on a comprehensive range of diagnostic applications. Imaging of the head and neck, the cardiovascular system, the abdomen, and the lungs is covered in depth, describing the application of multislice CT in a variety of tumors and other pathologies. Emerging fields such as pediatric imaging and CT-guided interventions are fully addressed, and emergency CT is also covered. Radiation exposure, dual-energy imaging, contrast enhancement, image postprocessing, CT perfusion imaging, and CT angiography all receive close attention. The new edition has been comprehensively revised and complemented by contributions from highly experienced and well-known authors who offer diverse perspectives, highlighting the possibilities offered by the most modern multidetector CT systems. This book will be particularly useful for general users of CT systems who wish to upgrade and enhance not only their machines but also their knowledge.

This excellent research based textbook addresses nursing care issues rather than disease processes and therefore looks at issues such as discharge planning, adolescents and cancer, coping strategies for family and staff. It concentrates on the psychological and social aspects of care and reflects the radical changes that have occurred in recent years in thisfield. These include better survival rates in childhood cancer, advanced therapies, the move to community based care and increasing awareness of the long term effects of treatment.All post-graduate nurses working with children with cancer, whether in a community or hospital setting will find this text invaluable. It will equally benefit post-graduate nurses studying professional and academic specialist courses such as the ENB 240 paediatric oncology course or those who are already qualified paediatric oncology nurses but who need to keep themselves updated or need a reference in this area.Expert contributors and editor in this field who will provide up-to- date and relevant analysis of the subject. Emphasises the partnership between nurse, child and family.Discusses the impact of treatment on the nursing team. This is an important chapter as there is a lack of knowledge regarding the emotional cost of caring for children with cancer.

The outlook for women with breast cancer has improved in recent years. Due to the combination of improved treatments and the benefits of mammography screening, breast cancer mortality has decreased steadily since 1989. Yet breast cancer remains a major problem, second only to lung cancer as a leading cause of death from cancer for women. To date, no means to prevent breast cancer has been discovered and experience has shown that treatments are most effective when a cancer is detected early, before it has spread to other tissues. These two facts suggest that the most effective way to continue reducing the death toll from breast cancer is improved early detection and diagnosis. Building on the 2001 report Mammography and Beyond, this new book not only examines ways to improve implementation and use of new and current breast cancer detection technologies but also evaluates the need to develop tools that identify women who would benefit most from early detection screening. Saving Women's Lives: Strategies for Improving Breast Cancer Detection and Diagnosis encourages more research that integrates the development, validation, and analysis of the types of technologies in clinical practice that promote improved risk identification techniques. In this way, methods and technologies that improve detection and diagnosis can be more effectively developed and implemented. Table of Contents Front Matter Executive Summary 1 Introduction 2 Benefits and Limitations of Mammography 3 Improving Breast Cancer Screening Services 4 Understanding Breast Cancer Risk 5 Biologically-Based Technologies 6 The Necessary Environment for Research and Development 7 Translating New Technologies into Improved Patient Outcomes 8 Recommendations Appendix A: Breast Cancer Technology Overview Appendix B: Workshop Agendas Appendix C: ROC Analysis: Key Statistical Tool for Evaluating Detection Technologies Appendix D: Common Weaknesses in Study Designs Glossary Index

This detailed, practical textbook focuses on immune mediated disorders of the nervous system with particular focus on systemic autoimmune disorders. Divided into three sections, the first discusses the neuroanatomical and pathophysiologic basis of immune mediated disorders of the nervous system. Following this are 25 chapters devoted to individual clinical conditions. To conclude, the final section explains what is known about the mechanisms of immunomodulatory treatments and practical points about monitoring patients on these treatments. Neurorheumatology: A Comprehensive Guide to Immune Mediated Disorders of the Nervous System bridges the gaps among different branches of medicine and is an indispensable resource for rheumatologists and neurologists looking to develop a firm understanding of these dynamic disorders

This volume explores the mechanisms of resistance to targeted therapeutics. The focus is on the cancer cell signaling network, although other mechanisms of resistance including target mutation, and new areas of study such as cancer stem cells are included. Targeted Therapies: Mechanisms of Resistance highlights examples of changes in the signaling network in response to inhibition of a signaling event and underscores the importance in having a mechanistic understanding of the signaling network in cancer for developing effective targeted cancer therapies. Moreover, cutting edge tools to analyze the cell signaling network will be discussed. This includes the leading edge of techniques as well as computational biology and systems theory. This volume provides the reader with both an overview as well as a detailed perspective on the mechanisms of resistance to targeted therapeutics and will be of great value to the oncologist, the physician-scientist treating patients and the translational scientist working on any aspect of targeted therapeutics.

In 1961 John F. Kennedy pledged to put a man on the moon by the end of the decade. Nine years later, Neil Armstrong and Buzz Aldrin walked on the moon. Ten years later, Richard Nixon echoed this pledge by declaring a 'war' on cancer. More than 30 years later, however, cancer remains one of the largest causes of death worldwide, with around 1 in 3 developing the disease. Curing cancer is not 'rocket science', but the question is, why has cancer proved to be harder to tackle than the moon landings turned out to be? Cancer research is a major economic activity. There are constant improvements in treatment techniques that result in better cure rates and increased quality and quantity of life for those with the disease, yet stories of breakthroughs in a cure for cancer are often in the media. In this Very Short Introduction Nick James, founder of the CancerHelp UK website, examines the trends in diagnosis and treatment of the disease, as well as its economic consequences. Asking what cancer is and what causes it, he considers issues surrounding expensive drug development, what can be done to reduce the risk of developing cancer, and the use of complementary and alternative therapies. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.

Bowel cancer, despite being the UK's second biggest cancer killer, still receives a shockingly low level of awareness. This book aims to redress this by telling the story of a mother of two who embarked on a crash course dealing with advanced bowel cancer at the age of 45. Having absolutely no preparation, her lists help her gain control over what fast becomes an even more chaotic and unpredictable life. Her diagnosis presents a wake-up call to what's important in life, and insists that daft and often funny things can still happen to people living with cancer. This is a memoir packed full of useful advice for making the best of your sudden situation - from learning how to deal with your new menagerie of medics to how to avoid all the usual cancer faux pas! As someone who describes herself as habitually "not doing today what I can put off till tomorrow", Rachel shares with you all the lists you need to cope with gaining back some control from the chaos. This is the ultimate reader-friendly guide on how to deal with operation after operation, the reality of chemotherapy and, when that's over, how to function on a daily basis with your 'new normal'. But most importantly, it's a record of how Rachel taught her children resilience, her number one challenge in life.

The authors have attempted to produce a fully-updated and comprehensive outline of the applications of exploitable nanoscience and nanotechnology in combating cancer. The study also introduces the reader to nucleic acids (especially dynamic DNA), gene mutations, virus-like particles, immunology and vaccines, plant nutraceuticals and the sunshine superstar (the wonder vitamin D) in the context of prevention, diagnosis and treatment of cancers. While taking the reader on an exciting journey through several disciplines such as ayurveda, allopathy, traditional and complementary medicine, chemotherapy and nanomedicine, some closely related issues of general health and diseases other than cancer are also touched upon briefly wherever relevant.

Improved cancer treatment and survival rates have resulted in a growing number of cancer survivors who live years, and even decades, after their cancer diagnosis. Insights into what the experience of cancer survivorship looks like and how it can be navigated are much sought after by cancer survivors and their families, loved ones, and communities as they chart this unfamiliar and often lonely territory. Approximately 53% of cancer patients are diagnosed when 65 years or older, yet no attempt to explore the experience of older cancer survivors has been made. Dr. Alice. Kornblith, an esteemed social psychologist with extensive experience working with cancer patients, aims to address this need in Older Survivors of Cancer: Feeling Understood by Sharing Experiences. This thoughtful, respectful book seeks to reduce older cancer patients' and survivors' feeling of aloneness and of not being understood by sharing narratives of other older cancer survivors' experiences. Narratives were gathered specifically for this book and relate experiences across different cancer diagnostic groups, phases of cancer and gender. Throughout, the reader learns how cancer affected their lives-physically, psychologically, spiritually, and socially-during each phase of their cancer journey. Commentary by Dr. Kornblith provides context and lessons learned from the narratives.

This book elucidates the radiation therapy protocols and procedures for the management of adult patients presenting with primary benign and malignant central nervous system tumors. With the development of new treatment strategies and rapid advancement of radiation technology, it is crucial for radiation oncologists to maintain and refine their knowledge and skills. Dedicated exclusively to adult CNS radiation oncology, this textbook explores CNS tumors ranging from the common to the esoteric as well as secondary cancers of metastatic origin. The first half of the book is organized anatomically: tumors of the brain, spinal cord, leptomeninges, optic pathway, ocular choroid, and skull base. The second half covers primary CNS lymphoma, rare CNS tumors, metastatic brain disease, vascular conditions of the CNS, radiation-associated complications, and radiation modalities. Each chapter provides guidance on treatment field design, target delineation, and normal critical structure tolerance constraints in the context of the disease being treated. Learning objectives, case studies, and Maintenance of Certification Self-Assessment Continuing Medical Education-style questions and answers are incorporated throughout the book. This is an ideal guide for radiation oncologists, residents, and fellows, but medical students may also find value in the text.

This book provides the most comprehensive and up-to-date knowledge of lymph node micrometastasis (LMM) and sentinel node navigation surgery (SNNS) in gastrointestinal cancers. Lymph node metastasis is a critically important prognostic factor in gastrointestinal tract cancers such as tumors of the esophagus, stomach, and colorectum. An understanding of the basic aspects of lymphatics and lymph nodes, including anatomy, histology, physiology, immunology, and molecular biology, is fundamental for physicians who are involved in cancer treatment. Furthermore, owing to the development of molecular and biological methodology, the precise recognition of LMM and its clinical significance have been clarified recently. At the same time, SNNS has actually been anticipated in treatment of breast tumors, and it is now being introduced in gastrointestinal tract cancer. For the application of SNNS, the detection of lymph node metastasis including LMM is extremely significant, because the presence of LMM determines the direction for surgery and chemo and/or radiation therapy. With these considerations in mind, the expert contributors to this book review basic and clinical approaches for LMM and SNNS including methodology for gastrointestinal cancers. Thus this volume benefits not only surgeons who treat gastrointestinal cancers but also clinical oncologists and medical scientists such as physiologists and pathologists.

This book provides a comprehensive, state-of-the art review of pediatric oncology. The text covers relevant concepts in molecular biology and addresses technical principles, applications, challenges, and integration of current and emerging genomic and molecular methods in the diagnosis and personalized management of childhood cancers. The text also discusses a wide array of pediatric neoplasms in the context of molecular pathology in a concise and understandable manner, with focus on their molecular pathogenesis, clinicopathological features, classification, molecular diagnosis, and approaches to personalized care. Written by experts in the field, Precision Molecular Pathology of Neoplastic Pediatric Diseases serves as a valuable resource for pathologists, pediatric oncologists, trainees and researchers with an interest in pediatric and molecular pathology.

This text serves as a very useful clinical guide and realistic approach to the clinical management of melanoma. Primary care physicians, specialists from varying areas of medical practice and numerous other healthcare providers will find this text to be quite useful as a standard daily reference and use in the office setting. It provides a clear and concise source of information in order to make real-life, evidence-based decisions for all aspects of management for cutaneous melanoma. This book also provides the latest breakthroughs in melanoma research, ranging from recent discoveries in genomics and epigenetics, to newly identified genes that have been selectively targeted for the development of a personalized approach to treatment. All chapters are written by specialists and true experts within their respective fields, incorporating the latest scientific, clinical and evidence-based medicine for melanoma (and non-melanoma skin cancers). This up-to-date information can be easily applied and translated to the clinical setting for the melanoma patient.