In the 1950s the direct observation of dislocations became possible, stimulat ing the interest of many research workers in the dynamics of dislocations. This led to major contributions to the understanding of the plasticity of various crys talline materials. During this time the study of metals and alloys of fcc and hcp structures developed remarkably. In particular, the discovery of the so-called in ertial effect caused by the electron and phonon frictional forces greatly influenced the quantitative understanding of the strength of these metallic materials. Statis tical studies of dislocations moving through random arrays of point obstacles played an important role in the above advances. These topics are described in Chaps. 2-4. Metals and alloys with bcc structure have large Peierls forces compared to those with fcc structure. The reasons for the delay in studying substances with bcc structure were mostly difficulties connected with the purification techniques and with microscopic studies of the dislocation core. In the 1970s, these difficulties were largely overcome by developments in experimental techniques and computer physics. Studies of dislocations in ionic and covalent bonding materials with large Peierls forces provided infonnation about the core structures of dislocations and their electronic interactions with charged particles. These are the main subjects in Chaps. 5-7."

It was a great honor for us to organize ChiCat, a symposium devoted to Chiral Reactions in Heterogeneous Catalysis and to be the hostsofmore than 120 scientists coming from everywhere in the industrialized world, to celebrate together one century of existence ofInstitut Meurice. This school was established in 1892when an industrial chemist, named Albert Meurice, decided to educate practical chemists according to the perceived needs ofthe industry ofthat time. This is exactly what we are still trying to do. It is the reason why, thirty years ago, we started a research activity in catalysis, and why we progressively devote this research to the applications of catalysis in the field of fine chemicals. In this respect, we are very close to another initiative of Albert Meurice, who started the first production of synthetic pharmaceuticals in Belgium during World War I. This business later on became a part ofthe Belgian corporation DCB, still very active in pharmaceuticals today. The school created by Albert Meurice merged in the fifties with another school that had been created to meet the same needs in the field of the food industries, mainly distilleries and breweries. This merger was done in the frame of the establishment of CERIA. For people in catalysis, ceria stands for cerium oxide, but for those who engineered the concept, CERIA stood for Center of Education and Research for the Food and Chemical Industries.

Larry L. Hench June Wilson OBJECTIVE Millions of people presently enjoy an improved quality of life due to prostheses which repair, augment or replace parts of their skeletal system: bones, joints, teeth, etc. However, all replacement parts have a finite probability of survival. The goal of this book is to compare the survivability data for various skeletal prosthesis systems. All data derive from previously published clinical studies. Where possible statistical comparisons are made and the reasons for failure are discussed. THE NEED FOR SKELETAL PROSTHESES We are an aging population with more than 100 million people in the U. S. and Europe over the age of 50 years. An unfortunate consequence of aging is a progressive deterioration of the quality of skeletal tissues. From the age of 30 years there is a decrease in bone mass for both men and women (Fig. 1. 1). However, for women it is much greater and between 40 and 60 years of age the rate of deterioration of long bones and vertebrae of women is especially severe due to hormonal changes. By the age of 70 most women will have lost from 35 to 60% of their bone mass. The loss of volume of cancellous or trabecular bone leads to a large decrease in mechanical compressive strength (Fig. 1. 2). The clinical consequence is an increasing incidence of vertebral collapse. Cortical bone decreases in tensile strength with age (Fig. 1.

Zeolites, with their crystalline microporous structures, are cordial hosts to a wide variety of guests. However, it was the abrupt and unexpected departure of one of these guests (water) from a host (stilbite) on heating which led Cronstedt, in 1756, to coin the term "zeolite" (from the Greek meaning "boiling stone") to describe this material. Since that time, approximately 40 different naturally-occurring zeolites have been discovered on earth. Recent studies of meteorite compositions have shown that these guest-host materials (e. g. , sodalite) occur in other parts of the universe as well. However, it wasn't until the twentieth century that synthetic routes to zeolites and other non-aluminosilicate molecular sieves were discovered. In addition, with the development of X-ray diffraction and the various spectroscopies, better understanding of the nature of the cavities, cages, and channels of these materials has led to the industrial exploitation of their guest-host properties. The world of zeolites has now expanded into a greater than 2 billion pound per year business, with major applications in detergent formulations, catalysis, and as adsorbents and desiccants. Their economic impact is difficult to determine; however, the improvement in gasoline yields alone (from catalytic cracking) must account for hundreds ofbillions ofdollars in increased GDP. In this volume, we have brought together a sampling of recent developments in various areas of guest-host or inclusion chemistry in zeolites.

The first International Conference on Ageing Studies and Lifetime Extension of Materials was held on th July 12-14 , 1999 at St. Catherine's College, Oxford, United Kingdom. Over 230 delegates attended during the three days and heard nearly ninety papers, together with over thirty poster presentations. Sixteen of these papers were keynotes from invited speakers eminent in their field of research. The proceedings were organised into six separate sessions: observation and understanding of real-time and accelerated ageing; experimental techniques; modelling and theoretical studies; lifetime prediction and validation; lifetime extension; and material design for ageing. In doing this, it was hoped to cover most issues of scientific concern inthefield ofmaterials ageing. One important aspect was that the conference did not concentrateon any particular group or type ofmaterial; rather the aim was to attract contributions from workers engaged in ageing studies with as wide a range of materials as possible. In this way, it was hoped that delegates could interactwith and learnfrom those whom they perhapswould not normally come across and that metallurgists could learn from polymer scientists, ceramicists could talk to modellers, and so on, in this important field. A read through the diverse papers contained within these proceedings will confirm that this aim was happily satisfied. Why hold such a meeting? In the modem world, engineered systems are expected to last longer.

Materials Chemistry is rapidly emerging as a key component of contemporary science. The strongly interdisciplinary nature of the field requires input from all branches of chemistry, from crystallography, from solid state physics and from computational and theoretical techniques. This book aims to give a coherent survey of the field by considering all the major aspects of the current study of the chemistry of materials. Early chapters emphasise basic principles and techniques. Strong emphasis is given to new techniques and technologies, for example, the opportunities opened up by new synchrotron sources in crystallography, and new computational techniques in simulation studies of complex materials. Characterisation techniques including crystallographic, microscopic and spectroscopic techniques are then described. Key contemporary themes such as atomic transport, reactivity and catalysis are reviewed. Later chapters focus on specific dasses of material, induding solid state ionics, ceramics (induding giant magneto-resistance and high temperature superconducting solids), microporous and molecular materials. We hope that the book provides a snapshot of the scientific and technological challenges in this fast developing field. The editors would like to thank the NATO Scientific Affairs Division for funding the School on which this volume is basedj financial contribution from Johnson Matthey Technology Centre is also gratefully acknowledged. We are most grateful to Mrs Jean Conisbee for all her efforts in preparing the manuscript.

Advances in nanoscale science show that the properties of many materials are dominated by internal structures. In molecular cases, such as window glass and proteins, these internal structures obviously have a network character. However, in many partly disordered electronic materials, almost all attempts at understanding are based on traditional continuum models. This workshop focuses first on the phase diagrams and phase transitions of materials known to be composed of molecular networks. These phase properties characteristically contain remarkable features, such as intermediate phases that lead to reversibility windows in glass transitions as functions of composition. These features arise as a result of self-organization of the internal structures of the intermediate phases. In the protein case, this self-organization is the basis for protein folding. The second focus is on partly disordered electronic materials whose phase properties exhibit the same remarkable features. In fact, the phenomenon of High Temperature Superconductivity, discovered by Bednorz and Mueller in 1986, and now the subject of 75,000 research papers, also arises from such an intermediate phase. More recently discovered electronic phenomena, such as giant magnetoresistance, also are made possible only by the existence of such special phases. This book gives an overview of the methods and results obtained so far by studying the characteristics and properties of nanoscale self-organized networks. It demonstrates the universality of the network approach over a range of disciplines, from protein folding to the newest electronic materials.

The papers contained herein were presented at the Second International Conference on Composite Structures (ICCS/2) held at Paisley College of Technology, Paisley, Scotland, in September 1983. The Conference was organised and sponsored by Paisley College of Technology in association with the Scottish Development Agency and the National Engineering Laboratory. It forms a natural progression from the highly successful First International Conference on Composite Structures (lCCS/l) held at Paisley in September 1981. The last few decades have seen phenomenal advances in research and of composite materials with new and exciting structural development possibilities being unearthed on an almost daily basis. Composites have been rightly heralded as space-age materials of the future. However, along with the rather specialised aerospace applications a growing awareness of the wider potential of composites is also unmistakable. The extensive composite materials research programmes of the fifties and sixties are now yielding fruit in abundance, with composites being used in virtually every area of structural engineering from transportation to pressure vessels and so on. Although significant weight savings, paramount in transportation engineering, are possible, composites have gone far beyond being simply lighter than conventional materials. They offer real structural advantages with almost unbounded potential. The ability to tailor a particular matrix material to suit prevailing environmental conditions whilst maintaining adequate reinforcement to withstand applied loading is unquestionably an attractive proposition.

Kinetic models have often served as useful examples in develop ing the methodology for the design and analysis of experiments in volving mechanistic models. Thus, it is not surprising that these approaches have been applied quite successfully to kinetic obser vations. Nevertheless, many ideas and methods were developed indepen dently in various fields of science. More often than not, investi gators working in one area have not been aware of relevant advances in others. In order to facilitate the desirable exchange of ideas, a one-day symposium was held in Toronto in conjunction with the XIth International Congress of Biochemistry. Biochemists, pharmacolo gists,> and statisticians came together and discussed many of the topics presented in this volume. Participants in the symposium believed that it would be use ful to publish a collection of the presentations together with some additional material. The present volume is the result. It is an attempt to convey some of the interdisciplinary concerns involv ing mechanistic, and especially kinetic, model building. The coverage is by no means exhaustive: many principles, methods, and problems are not included. Even the applications are limited to biochemistry and pharmacology. Still, the symposium highlighted areas of current interest. These included questions of weighting, robust parameter estimation, pooled data analysis, model identification, and the design of experiments. These topics, which are of interest in many fields of science, are discus3ed also in the present volume.

Polymer composites were introduced for the aerospace industry as light, strong, stiff materials, and adopted by the construction and automobile industries, among others. Meanwhile, composite materials have been introduced to fulfill the uses that these conventional materials could not, such as in extreme environments. The research for new composites includes not only new polymer systems, but metals, ceramics and intermetallic systems as well. This volume contains a selection of recent work by leading researchers in micromechanics on the topics of prediction of overall properties of elastic, perfectly bonded systems, problems associated with inelastic deformation of the phase, debonding at interfaces and growth of distributed damage. Many familiar aspects of mechanical behavior, such as fatigue, fracture, strength and buckling, etc. have been reexamined and adapted for these new systems.

The emergence of civil aviation as a means of mass transportation is primarily due to the large scale construction of jet airplanes in the past 30 years or so. A large number of these jet airplanes is currently operating at or beyond their designed fatigue lives. Thus, the structural integrity of these aging airplanes has become an issue of major concern to all nations of the world. To bring the needed technical and research focus on the issues involved in the life-enhancement and safety-assurance of aging airplanes, the Federal Aviation Administration sponsored a symposium in Atlanta, GA, USA, during 20-22 March 1990. This symposium, under the title "International Symposium on Structural Integrity of Aging Airplanes. was organized jointly be the Georgia Institute of Technology (Center for Computational Mechanics) and the Transportation Systems Center (Cambridge, MA) of the U.S. Department of Transportation. Industrial and academic experts from several countries in North America, Europe and Asia, were invited to discuss their experiences and proposed solutions. This monograph contains the original papers that represent the expanded and edited versions of the talks presented at this symposium. This book aims to bring the collective experience, from across the world, with problems related to the structural integrity of aging airplanes to the attention of the professional and research community at large - in the hope that it may stimulate further fruitful research on this important topic of global concern."

Tradi tionally, the International lTV - Conferences on Biomate rials are focussing on problems in Biomedical Engineering, problems, which are still unsolved, of main interest, and which are of interdisciplinary character. In 1983, the Division of Biomedical Engineering of the Institute of Textile Technology and Chemical Engineering, Denkendorf, started wi th a conference about the use of polyurethanes in biomedicine. Three years later, . in 1986, progress in development and use of polyurethanes was selected as conference topic. It had to be realized that degradation problems were still dominating the discussions. The main discussion topics were: What are the causes for the degradation? How can one prevent them? What are the degradation products, and do they affect the human body? How can one simu late the degradation? How can one accelerate the in vitro tests and how can the results predict the in vivo behaviour of the material? How do in vitro tests correlate with animal tests and the behaviour in the human body? At the third conference in 1989, the speakers focused on the use of textiles in medicine. Again the problem of degradation was discussed intensively and demonstrated by the failure of textile implants, the degradation of aramide polymers or the degradation of resorbable suture materials. The examples make clear, that degradation may be a desired or undesired property of an implant."

We are again proud to present an excellent volume of contemporary topics in NMR and EPR to the biological community. The philosophy behind the volume and the presentation of each chapter remains at the high level reflected in our earlier volumes: to be current, pedagogical, and critical. The first chapters, as always, address a subject related to in-vivo biology. Gabby Elgavish addresses NMR spectroscopy of the intact heart. lain Campbell and colleagues present a state-of-the-art description of NMR methods for probing enzyme kinetics in intact cells and tissues. Klaus Mobius and Wolfgang Lubitz have produced a thorough review of the principles and applications of ENDOR spectroscopy in photobiology and biochemistry including discussions of liquid and solid state ENDOR as well as CIDEP-enhanced ENDOR. The final chapter by Hans Vogel and Sture Forsen addresses a contemporary problem in inorganic biochemistry, namely cation binding to calcium binding proteins. We are pleased to announce that a special forthcoming volume will be devoted entirely to the subject of "Spin Labeling: Theory and Applications (3rd compendium)." A substantial degree of progress has occurred in this important area of ESR in biology since the last treatise on the subject in 1979. Lastly, we acknowledge our colleagues in the field who continue to support this excellent series both as subscribers and contributors. We pledge to continue servicing the community as long as the need exists.

The summer school on "Silicon: Materials Science and Technology" was held at the Ettore Majorana Centre for Scientific Culture in Erice, Sicily. It was the 16th course of a series in the International School of Materials Science and Technology. The course attracted participants from all over the world. 30 lectures were presented by internationally reputed experts in the field. The proceedings include all the lecture topics of the course. Short notes on the scientific work of the attendees are integrated with the main papers. The semiconductor material silicon is of paramount importance in micro electronics. The various aspects of the silicon materials science and its technol ogy were critically reviewed and the forseeable future developments of devices and integrated circuits were discussed during the two weeks of the course. The topics ranged from the fundamental physics to the applied science of processing technology and device fabrication covering crystal growth, processing technol ogy, defects, measurement methods, thin films, and device problems. The course brought together theoretical and experimental physicists and engineers from universities, research institutes and industry. The unique setting of the Ettore Majorana Centre in the ancient town of Erice created a friendly atmosphere for fruitful scientific exchange. Long dis cussions continued over lunch and only ended late at night in the wine cellar of the school."

This book is a collection of the addresses of the keynote speakers and invited lecturers as well as manuscripts of a few outstanding papers which were delivered at the First Pacific Polymer Conference organized by the Pacific Polymer Federation in Maui, Hawaii, 12-15 December, 1989. The First Pacific Polymer Conference covered a wide variety of topics in macromolecular science, demonstrating the emphasis given to polymer research in the Pacific Rim countries. The keynote speakers and invited lecturers are excellent scientists and leaders of effort who covered their fields expertly and in many cases gave their own perspective on the future of polymer science and engineering. A panel discussion on the role of polymers in the arts interested the attendees and emphasized the pervasiveness of polymers in all facets of life. The meeting was attended by over 500 scientists from all over the world. The participants left the meeting with renewed feeling for the importance of polymers in the material sciences and impressed by the progress in polymer research and development. This book, therefore, provides a wide -angle snapshot of the polymer research as we enter the 1990's. It is a useful book for all scientists interested in polymers and the progress of our science in the countries of the Pacific Rim. We hope that many attendees were stimulated by the meeting and that new ideas and new collaborations will result which will further enrich research, and lead to new useful polymers for all countries.

Owing to efforts and legislative action - initiated above all by the government of the United States - to use cleaner fuels and thus make a contribution towards a better environment, public attention is back again on using methanol in carbu rettor and diesel engines. Most prominent among the raw materials from which methanol can be produced is coal, whose deposits and resources are many times larger than those of liquid and gaseous hydrocarbons. This book deals with the production of methanol from coal. It describes both the individual steps that are required for this process and the essential ancillary units and offsites associated with the process itself . . It is not meant to inform the reader about the intricate details of the processes, which can much better be taken from the specialized literature that deals exclusively and in detail with them or from the well-known standard engineering books. Rather, this book is to give the reader an impression how manifold a field this is, how many process variations and combinations the designer of such plants has to consider in order to arrive at an optimum design in each particular case. Apart from the production of chemical-grade methanol, the book deals briefly also with fuel methanol production, i. e. with the production of alcohol mixes. One of the many possible routes from coal to methanol is illustrated by a process flow diagram, and a material and energy balance is compiled for this typical example."

From the reviews: "The book should be acquired by all libraries with an interest in glass science and applications...the title will endure for many years as the standard work on the properties of optical glass." Optical Systems Engineering

Keynote and lectures from invited speakers given at the Se- cond Pacific Polymer Conference in Otsu, Japan, are collec- ted in this book. Eminent Polymer Scientists from both aca- demic and industrial fields around the Pacific Basin contri- buted on the following topics: - Polymer Synthesisand Ractions - Polymer Characterization - Structure-Property-Relationships - High Performance Polymers - Bio-Related Polymers With contributions by H.R. Allcock, R.G. Davidson, T. Inoue, Y.H. Kim, E.A. McCullough, J.E. McGrath, G.F. Meijs, T. Nishi, Y.Nishida, I. Noda, R.M. Nowak, M. Okamoto, R.E. Prud'homme, J.P. Riggs, D.N. Schulz, D.H. Solomon, J. Sunamoto, M. Takayanagi, a.o.

Modern polymer materials are designed by applying principles of correlation between chemical structure, physical macrostructure and technological properties. Fundamentals of polymer physics are explained in this book without excessive use of calculations. Four main sections treat relaxation of polymers, melting and crystallization, the mechanism of deformation in thermoplastics, elastomers and multiphase systems, and thermodynamics of mixing and swelling of polymers and polymer networks. The book presents the theoretical models of polymer physics in a comprehensive style and relates their applicability to real polymer systems in terms of the available experimental observations.

In recent years it has been recognized that tundishes playa critical role in affecting the quality of the finished steel products. Furthermore, proper tundish design may be even more important in the development of the novel continuous casting pro cesses that are now in varying stages of realizatic)ll. Traditionally, physical modeling has played a key role in tundish design, but the recently evolved computational software packages, the readily accessible computa tional hardware, and, perhaps most important, the growing experience with tackling a broad range of computational fluid flow problems within a metallurgical context have made mathematical modeling an important factor in this field. Our aim in writing this book has been to bring realistic perspectives to tundish design. The main purpose is to provide a good physical understanding of what is happening in tundishes, together with a realistic discussion of topics that are still not quite clear. The process metallurgist active in this field has many tools at his or her disposal, including mathematical modeling, physical modeling, and measure ments on full plant-scale systems. In this monograph we seek to show how these ideas may be combined to provide a good basic understanding and, hence, an attempt at an optimal design."

Residual stresses are always introduced in materials when they are produced, or when they undergo non-uniform plastic deformation during use. The circumstances that can cause residual stresses are therefore numerous. Residual stresses exist in all materials and, depending on their distribution, can playa beneficial role (for example, compressive surface stress) or have a catastrophic effect, especially on fatigue behaviour and corrosion properties. The subject of residual stresses took form around 1970 with the development of methods to measure macroscopic deformations during the machining of materials or on an atomic scale by X-ray diffraction. These techniques have made considerable progress in the last 20 years. The meetings organized in several countries (Germany, France, Japan, etc. ) have largely contributed to this progress, aided by the numerous exchanges of information and knowledge to which they have given rise. Studies of the formation of residual stresses began more slowly, but have progressed with the emergence of increasingly realistic models of materials behaviour and with access to ever more powerful codes for numerical calculations. Two successive meetings for discussing this topic have been held in Europe. The first, held in 1982 in Nancy (France), consisted of 30 participants from 5 countries. The second was held in Linkoping (Sweden) in 1984, with 80 participants of 16 nationalities. It was decided to hold a first International Conference, ICRS, to address all aspects of the problem. Held in 1986 in Garmisch-Partenkirschen (FRG), it was an assembly of neady 300 participants from 21 countries.

For a number of years it has been a General Motors Research Laboratories custom to hold a symposium on a subject which is new and emerging, and to invite the best people in the world in that subject to come together to talk to each other. Initially, I had some difficulty in regarding foundry processes as a new and emerging subject. Copper alloys have been in foundry practice for about six thousand years. Foundrymen working with those alloys have been recognized, as such, for nearly all that time. Iron has a much shorter history, probably only three or four thousand years. So what's new? What is new is that a subject which has always been so complex and so difficult that it could only be a craft skill, with bits and pieces of knowledge and bits and pieces of insight, has begun to yield to new abilities to solve very complex problems. We do this now because we can handle great amounts of data by computational means, using new and more complicated theoretical treatments than we could deal with before. In fact, we have a new technology with which we can attack these terribly difficult problems. Thus, foundry processing is becoming a new subject because new things can be done with it.

The present volume contains the texts of the invited talks delivered at the Fifth International Conference on Recent Progress in Many-Body Theories held in Oulu, Finland during the period 3-8 August 1987. The general format and style of the meeting followed closely those which had evolved from the earlier conferences in the series: Trieste 1978, Oaxtepec 1981, Altenberg 1983 and San Francisco 1985. Thus, the conferences in this series are in tended, as far as is practicable, to cover in a broad and balanced fashion both the entire spectrum of theoretical tools developed to tackle the quan tum many-body problem, and their major fields of. application. One of the major aims of the series is to foster the exchange of ideas and techniques among physicists working in such diverse areas of application of many-body theories as nucleon-nucleon interactions, nuclear physics, astronomy, atomic and molecular physics, quantum chemistry, quantum fluids and plasmas, and solid-state and condensed matter physics. A special feature of the present meeting however was that particular attention was paid in the programme to such topics of current interest in solid-state physics as high-temperature superconductors, heavy fermions, the quantum Hall effect, and disorder. A panel discussion was also organised during the conference, under the chair manship of N. W. Ashcroft, to consider the latest developments in the extreme ly rapidly growing field of high-T superconductors."

Engineering structures for reliable function and safety have to be designed such that operational mechanical loads are compensated for by stresses in the components bearable by the materials used. Vhat is "bearable"? First of all it depends on the properties of the chosen materials as well as on several other parameters, e.g. temperature, corrosivity of the environment, elapsed or remaining serviceable life, unexpected deterioration of materials, whatever the source and nature of such deterioration may be: defects, loss of strength, embrittlement, wastage, etc. DEFECTS and PROPERTIES of materials currently determine loadability. Therefore in addition to nondestructive testing for defects there is also a need for nondestructive testing of properties. The third type of information to be supplied by nondestructive measurement pertains to STRESS STATES under OPERATIONAL LOADS, i.e. LOAD-INDUCED plus RESIDUAL STRESSES. Residual stresses normally cannot be calculated; they have to be measured nondestructively; well-approved elastomechanical finite element codes are available and used for calculating load-induced stresses; for redundancy and reliability, engineers, however, need procedures and instrumentation for experimental checks.