This text is a review of molecular immunohematology (MI). It draws from analyses and case studies around the world and details many techniques used in many labs. It is aimed at anyone interested in how MI is changing blood bank and transfusion medicine.

This new edition provides undergraduate students with the most recent advances in haematology and clinical pathology. Divided into four sections, the book begins with an explanation of the diagnosis and management of numerous disorders of both red and white blood cells. Section three covers disorders associated with haemostasis (clotting), and the final section on clinical pathology discusses both haematological and non-haematological laboratory investigations. The second edition has been fully revised and includes new chapters on automation in haematology, urine analysis, atoll examination, and clinical scenarios. Each chapter begins with a chapter outline and ends with a summary of key points. Self assessment exercises with essay-type questions, short notes and MCQs are included at the end of each topic to assist revision. Key Points Fully revised and updated second edition providing latest advances in haematology and clinical pathology for undergraduates Each chapter includes self assessment exercises, short notes and MCQs Features nearly 400 illustrations and tables Previous edition (9789350255995) published in 2011

Sickle cell disease (SCD) is a genetic disorder caused by an abnormality of hemoglobin. The disease is characterized by a chronic hemolytic anemia. The search for affordable and accessible medicines mainly from plants and having various modes of actions for managing SCD is a priority in Africa where the disease is endemic. The first chapter in this book reviews children with Sickle Cell Disease (SCD). The authors also present their research that shows that clinically, children with SCD behave differently regarding their genetics. The second chapter gives an overview of the current progress in research in calcium handling in red blood cells of sickle cell disease patients, followed by an outlook into the potential use of blockers of the cation channels for therapy of SCD patients. The third chapter reviews and validates the pharmacological relevance of "Gardenia ternifolia" and sustains the use of this herbal medicine in the management of SCD in traditional medical systems. The fourth chapter reviews the search and the development of antisickling herbal drugs in Africa, where Sickle cell disease (SCD) is an endemic. The last chapter reviews SCD and its impact on sexual functioning as well as relationship dynamics. Conclusions support the importance of social support and its far-reaching impact into the coping mechanisms of patients with chronic illness as well as quality of life.

Developed specifically for student nurses and based on the author's over thirty years of teaching experience, Interpreting Arterial Blood Gases the Easy Way teaches students a step-by-step method for interpreting blood gases and helps them learn how to apply the interpretations. The booklet is divided into two parts. Part I teaches students to differentiate between acidic and alkaline states, identify respiratory or metabolic changes in blood gases, and recognize compensated, partially compensated, and uncompensated states. In Part II students apply what they have learned in order to recognize signs and symptoms of abnormal blood gases, identify appropriate interventions, and understand the meaning and significance of specific oxygenation levels. Clear and well-organized, the material features quizzes for self-evaluation, critical thinking questions, and tips that may assist with the National Council Licensure Examination. Knowledge of basic physiology and acid-base balance is recommended before using the booklet, but the information is also reviewed. Interpreting Arterial Blood Gases the Easy Way is an excellent choice for nursing programs. It can also be used in training respiratory therapists and emergency medical technicians.

Mantle cell lymphoma (MCL) is a subtype of Non-Hodgkin's Lymphoma (NHL) with varying clinical presentations, ranging from indolent disease to highly aggressive symptoms. MCL represents approximately 3-10% of non-Hodgkin lymphomas, and has increased in incidence over the past several decades. The majority of patients respond to initial therapy, but remission duration is typically short. This book discusses the clinical characteristics of mantle cell lymphoma, as well as its prevalence and examines several treatment options available.

Decreased platelet counts can be due to a number of disease processes causing decreased platelet production, increased platelet destruction, or can be medication-induced. Health care providers have to differentiate inherited thrombocytopenias, primary immune thrombocytopenias (ITP), secondary immune thrombocytopenias, myelodysplastic syndromes with thrombocytopenia, bone marrow failure syndromes and non-immune thrombocytopenias. ITP is the most common cause of isolated thrombocytopenia. This book focuses on discussing ITP in adults; new treatment for ITP; thrombocytopenia during pregnancy; the different diagnosis of thrombocytopenia; heparin-induced thrombocytopenia; and thrombocytopenia in dengue.