Vorliegendes kleines Buchlein war zuerst als monographisches Kapitel erschienen in Carl Neubergs Handbuch del' Ausschei dungen und Korperflussigkeiten 1911 bei Jul. Springer. Es war gedacht und abgefaBt als ganz elementarer Wegweiser fur die notwendigsten und wichtigsten Untersuchungsmethoden des Blutes vom Standpunkt etwa des Chemikers und Pharmazeuten. Bald nach Erscheinen ergingen zahlreiche Aufforderungen an mich, das Kapitel doch gesondert erscheinen zu lassen. Da in del' Tat ein iihnlich kurz gehaltenes Kompendium bisher in diesel' Form nicht existiert, auch dieses vorwiegend mikro"kopisch-cytologische Kapitel in dem uberwiegend physio logisch-chemischen Handbuch eine gewisse Sonderstellung ein nahm, welche bedingte, daB die Hauptinteressenten dieses Kapitels ganz andere sind als die Interessenten del' sonstigen Kapitel des Werks, so entschloB sich del' Herr Verleger in entgegen kommender Weise, den geauBerten Wiinschen nachzugeben. Das Buchlein unterscheidet sich von allen ahnlichen darin, daB es nur die wirklich wel'tvollen, wichtigen sowie die praktisch not wendigsten klinischen, eigentlich hamatologischen Untel' suchungsmethoden des BIutes bringt. Alle weniger notwendigen und bloB chemischen odeI' physikalischen Methoden (wie Alkali 'metrie, spez. Gewicht, Volumetrie, Trockenriickstand, Gerinnungs zeit, Viskosimetrie usw. usw.) sind fortgelassen. Auch von den 3 eigentlichen hamatologischen Kardinalmethoden (Farbung, Zahlung, Hb-Bestimmung) sind nul' die wirklich praktisch best bewahrten und ausreichendenMethoden abgehandelt, aller sonstiger Ballast an weniger notwendigen Farbungs- und Farbstoff bestimmungsmethoden ist fortgelassen. 1m AnschluB an die bloBe absolute Methodologie sind auch die betreffenden normalen VerhliJtnisse des BIutes sO\yie die wichtigsten semiologischen Gesichtspunkte zur Be" ertu.ng des pathologischen BIutes bei jedem Kapitel kurz besprochen."

Our understanding of myeloproliferative neoplasms (MPN) disorders, a group of clonal haematological malignancies characterized by excessive accumulation of one or more myeloid cell lineages, has grown considerably over the past four decades. Myeloproliferative Neoplasms offers a detailed evidence-based guide to MPNs in an easily accessible format, structured to facilitate learning specialist information by presenting core information in 'bite size' chunks. Each chapter summarises the state-of-the art preclinical and clinical knowledge, and its impact on the clinical management of patients with MPNs. This practical guide, written by experts in the field, is essential reading for oncologists, haematologists, and other health care professionals interested in the field of MPNs.

Blood is vital to most animals. In mammals it transports oxygen and food, carries away waste, and contains the white cells that attack invading microbes. Playing a central role in life, it has had profound cultural and historical significance and plays an important role in religious ritual. Blood was one of the four humours in early Western medicine and is still probably the major diagnostic tool in the doctor's armoury. In this Very Short Introduction, Chris Cooper analyses the components of blood, explains blood groups, and looks at transfusions, blood tests, and blood-borne diseases. He considers what the future may hold, including the possibility of making artificial blood, and producing blood from stem cells in the laboratory. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.

Cancer is a very aggressive disease and currently it has been considered a challenge to oncologists and cancer patients worldwide. Nowadays, several therapeutic strategies had improved toward last decades. Surgery is many times still the best curative treatment, mainly in early stage disease. However, Radiotherapy and chemotherapy acquired a main role in this scenario. Target therapies were introduced for medical oncology practice and are demonstrating a hallmark of a new era in cancer treatment. More recently, immunotherapy has been considered the novel cornerstone in cancer treatment. The 2nd edition of the International Manual of Oncology Practice (iMOP) emerged after the great success of the iMOP 1st edition as a reference for medical oncologists and medical residents in the field. In this edition, several chapters were revised and its addresses from the molecular issues of cancer sciences to the clinical practice in medical oncology. In addition, multiple choice questions and clinical cases were included in the main chapters in order to improve the reader learning. The book focuses systemic treatments in many areas of medical oncology, such as breast cancer, gastrointestinal, thoracic, urological oncology, head and neck tumors, bone tumors, sarcomas and palliative care. The topics herein discussed will provide the readers a step forward in the medical oncology practice understanding and give facilities for help in cancer patient treatments.

This book summarizes current knowledge on chronic lymphocytic leukemia (CLL), taking into account the most recent research. All aspects are considered, including pathophysiology, clinical presentation, diagnosis, prognosis, treatment, follow-up, and complications and their management. Readers will find important information on the various prognostic markers as well as practical guidance on the use of different diagnostic procedures. A key focus of the book is the changing treatment paradigm in CLL as progress in understanding of pathogenesis and pathophysiology leads to the identification of new potential therapeutic targets. General treatment concepts are clearly described, and it is explained how choice of treatment for CLL depends on stage, age, and performance status as well as specific genetic aberrations. In addition, frontline therapeutic strategies for disease relapse, including allogeneic stem cell transplantation, are reported. Looking beyond CLL, the diagnosis and therapy of T-cell prolymphocytic leukemia and T-cell large granular lymphocyte leukemia, two rare CLL-related entities, are addressed.

John John is a healthy 14 year old, 6ft tall boy that always had a smile on his face. He is an excellent student in school and is well liked by his peers and teachers. Johnathan is like any other kid and enjoys playing games, listening to music, and getting on Facebook to communicate with those near and far. He also loves to play basketball and was recruited by his gym teacher to play for the school team. Then out of the blue, John John became deathly ill. Our whole world changed after then.