The essential guide to making sure you have a fabulous later life. You're likely to live longer than you think. Today's fifty-year olds could have an astounding 36 or more years of life. What's your dream life for your later years? When We're 64 is a friendly, practical guide to preparing for what could be the best years of your life - from the essentials on work and how to fund retirement, to volunteering, where to live and what kind of housing you'll need. It covers how to stay healthy - and still live a full life if you get a health condition - and reveals how your attitude to ageing could actually increase your lifespan. There are sections on relationships with family and friends, as well as caring for older relatives and how to tackle loneliness. Packed with expert advice and new evidence and tips on how to age well, this route map will help you plan and prepare for the future.

The effects of the bone morphogenetic proteins (BMPs) family on bone formation are well documented, but the transforming growth factor (TGF)-beta ( ) isoforms are much less studied. The product of 20 years of study, Induction of Bone Formation in Primates: The Transforming Growth Factor- 3 sums up editor Ugo Ripamonti's research into the osteogenic activity of the three mammalian TGF- isoforms, particularly in primates. It explores how the mammalian TGF- isoforms have the potential to shed light on the apparent redundancy of bone induction signaling. The book unearths the profound and important bone inductive activity of the TGF- 3 isoform. It includes accounts of extensive research in non-human primates from craniofacial tissue regeneration, heterotopic tissue induction, and chapters on periodontal tissue regeneration and synergistic induction of bone formation. It also discusses the future clinical role of the TGF- isoform, including in human studies. This book contributes to the fascinating history of BMP and TGF- research at the intersection of molecular biology, tissue induction, bone regeneration, and craniofacial surgery. It provides a revolutionary awakening to new possibilities in skeletal reconstruction, tissue engineering, and molecular and cellular biology.

This book provides a state-of-the-art overview of key areas of subcellular aging research in human cells. The reader is introduced to the historical development and progress in biomedical aging research and learns, for example, about the role of microRNAs, circRNAs, mitochondria and extracellular vesicles in cellular senescence. The reader will also learn more about how gap junctions, the nuclear pore complex and the proteasome are affecting the ageing processes. In addition, novel therapeutic opportunities through modulation of cellular senescence are discussed. The book follows on from Parts I and II of Biochemistry and Cell Biology of Ageing (Volumes 90 and 91 of the Subcellular Biochemistry book series) by covering interesting and significant biomedical ageing topics not included in the earlier volumes. Comprehensive and cutting-edge, this book is a valuable resource for experienced researchers and early career scientist alike, who are interested in learning more about the fascinating and challenging question of why and how our cells age.

Biology of Aging, Second Edition presents the biological principles that have led to a new understanding of the causes of aging and describes how these basic principles help one to understand the human experience of biological aging, longevity, and age-related disease. Intended for undergraduate biology students, it describes how the rate of biological aging is measured; explores the mechanisms underlying cellular aging; discusses the genetic pathways that affect longevity in various organisms; outlines the normal age-related changes and the functional decline that occurs in physiological systems over the lifespan; and considers the implications of modulating the rate of aging and longevity. The book also includes end-of-chapter discussion questions to help students assess their knowledge of the material. Roger McDonald received his Ph.D. from the University of Southern California and is Professor Emeritus in the Department of Nutrition at the University of California, Davis. Dr. McDonald's research focused on mechanisms of cellular aging and the interaction between nutrition and aging. His research addressed two key topics in the field: the relationship between dietary restriction and lifespan, and the effect of aging on circadian rhythms and hypothalamic regulation. You can contact Dr. McDonald at [email protected]. Related Titles Ahmad, S. I., ed. Aging: Exploring a Complex Phenomenon (ISBN 978-1-1381-9697-1) Moody, H. R. & J. Sasser. Gerontology: The Basics (ISBN 978-1-1387-7582-4) Timiras, P. S. Physiological Basis of Aging and Geriatrics (ISBN 978-0-8493-7305-3)

The scientific study of aging is a relatively nascent field of inquiry. Although philosophic and literary reflections on what it means to grow older appear in the earliest historical records, the systematic study of aging began in earnest about a century ago. Scholarly interest in the topic has accelerated in recent decades, due in part to rapid population aging in developed nations. As a result, the study of aging has been incorporated into many disciplines, emphasizing concepts, theories, and methods to elucidate the antecedents and consequences of growing older. Although each discipline has key concepts and empirical generalizations about aging, there is little agreement across disciplines about the intellectual core of gerontology. Each discipline brings its own intellectual heritage and perspective to the study of aging, but the question posed by author Ken Ferraro is whether there is an emergent perspective or way of thinking about aging that transcends the disciplines. Biologists, psychologists, and sociologists may claim an interest in gerontology, but do they have a common image of aging or a set of principles to guide their research? Do they share a paradigm-a fundamental image of aging-that incorporates concepts and empirical generalizations from multiple disciplines? And when disciplinary approaches to gerontology clash, which approach or conceptualization of aging is likely to emerge as part of the paradigm? Although biologists, psychologists, and social scientists share an interest in the study of aging, they are distinctive in how they conduct their research. The Gerontological Imagination provides an integrative paradigm of aging that makes it the first book to identify intellectual common ground among scholars studying aging. Ferraro identifies an underlying set of principles that constitute a paradigm for the study of aging: causality, life course analysis, multifaceted change, heterogeneity, accumulation processes, and ageism. The proposed paradigm provides an efficient way to identify and interpret essential ideas, findings, models, and theories across multiple disciplines that study aging.

Think diet and exercise are the keys to a long, healthy life?
Think again.

What can you do to increase the likelihood of living a happy, healthy, fulfilling life into your sixties, seventies, eighties, and beyond?

For more than five decades Harvard Medical School has studied the basic elements of adult human development, analyzing the health and happiness of hundreds of individuals from a wide variety of backgrounds. In Aging Well, George E. Vaillant, M.D., the director of the study, draws on the data gathered and reveals for the first time why some people turn out to be more resilient than others. His surprising conclusion is that individual lifestyle choices play a greater role than genetics, wealth, race, or other factors in determining how happy people are in later life.

Among the topics Dr. Vaillant explores:

• · The importance of marriage and the impact of divorce
• · The role of play and creative activity
• · The effects of tobacco, alcohol, and other mood elevators
• · The benefits of forming new friendships and new social networks
• · The importance of intellectual curiosity and lifelong learning

With its step-by-step advice and its revelation of scientific secrets, this inspiring book can help you — whether you are thirty-five or sixty-five — ensure that your golden years are truly golden.

When Near Becomes Far explores the representations and depictions of old age in the rabbinic Jewish literature of late antiquity (150-600 CE). Through close literary readings and cultural analysis, the book reveals the gaps and tensions between idealized images of old age on the one hand, and the psychologically, physiologically, and socially complicated realities of aging on the other hand. The authors argue that while rabbinic literature presents a number of prescriptions related to qualities and activities that make for good old age, the respect and reverence that the elderly should be awarded, and harmonious intergenerational relationship, it also includes multiple anecdotes and narratives that portray aging in much more nuanced and poignant ways. These anecdotes and narratives relate, alongside fantasies about blissful or unnoticeable aging, a host of fears associated with old age: from the loss of physical capability and beauty to the loss of memory and mental acuity, and from marginalization in the community to being experienced as a burden by one's children. Each chapter of the book focuses on a different aspect of aging in the rabbinic world: bodily appearance and sexuality, family relations, intellectual and cognitive prowess, honor and shame, and social roles and identity. As the book shows, in their powerful and sensitive treatments of aging, rabbinic texts offer some of the richest and most audacious observations on aging in ancient world literature, many of which still resonate today.

The effects of the bone morphogenetic proteins (BMPs) family on bone formation are well documented, but the transforming growth factor (TGF)-beta ( ) isoforms are much less studied. The product of 20 years of study, Induction of Bone Formation in Primates: The Transforming Growth Factor- 3 sums up editor Ugo Ripamonti's research into the osteogenic activity of the three mammalian TGF- isoforms, particularly in primates. It explores how the mammalian TGF- isoforms have the potential to shed light on the apparent redundancy of bone induction signaling. The book unearths the profound and important bone inductive activity of the TGF- 3 isoform. It includes accounts of extensive research in non-human primates from craniofacial tissue regeneration, heterotopic tissue induction, and chapters on periodontal tissue regeneration and synergistic induction of bone formation. It also discusses the future clinical role of the TGF- isoform, including in human studies. This book contributes to the fascinating history of BMP and TGF- research at the intersection of molecular biology, tissue induction, bone regeneration, and craniofacial surgery. It provides a revolutionary awakening to new possibilities in skeletal reconstruction, tissue engineering, and molecular and cellular biology.

In Neurosis and Human Growth, Dr. Horney discusses the neurotic process as a special form of the human development, the antithesis of healthy growth. She unfolds the different stages of this situation, describing neurotic claims, the tyranny or inner dictates and the neurotic's solutions for relieving the tensions of conflict in such emotional attitudes as domination, self-effacement, dependency, or resignation. Throughout, she outlines with penetrating insight the forces that work for and against the person's realization of his or her potentialities. First Published in 1950. Routledge is an imprint of Taylor & Francis, an informa company.

Research documents that rural elders are poorer, live in less adequate housing, and have far fewer health and service options available to them than their urban counterparts, yet there is a critical lack of current and detailed information on the problems facing rural elders and on the professional practices that serve this population. This text fills this gap by introducing readers to rural areas and their residents and discussing the issues, programs, and policies designed to meet their needs. Through a multidisciplinary lens, it examines and defines specific competencies required for successful work with older adults and their families in these communities.

The text presents a research-driven, competency-based approach for the health and human service professionals who work with older rural residents. It discusses both the problems facing older adults and their families and evidence-based solutions regarding policy and best practices. Key issues examined include health and wellness, transportation, housing, long-term care, income, employment, and retirement, along with the needs of special populations (ethnic minorities, immigrants, and the LGBT population). Case examples reinforce an interdisciplinary model that addresses practice with rural elders that encompasses professional competencies, values and ethics, and the roles of a spectrum of health and human service professionals. The text also examines current policies affecting health and social services to rural elders and recommendations for policy change to build an effective health and human service workforce in rural communities. Links to Podcast interviews with scholars and respected professionals working in the field and "Spotlight" excerpts from the text reinforce information. In addition, the text provides discussion questions, PowerPoint slides, a test question bank, and suggested activities and exercises.

Key Features: Fills a vacuum regarding information on health and social services for rural elders Provides current and comprehensive knowledge about issues besetting this population and programs and policies designed to meet their needs Examines and defines specific competencies required for effective health and social services Based on a research-driven, competency-based, interdisciplinary approach to policy and best practice Includes links to Podcast interviews with scholars and respected professionals in the field

"Motor Learning and Performance: From Principles to Application, Fifth Edition With Web Study Guide," describes the principles of motor performance and learning in a style that is accessible even to students with little or no knowledge of physiology, psychology, statistical methods, and other basic sciences. Constructing an easy-to-understand conceptual model of motor performance along the way, this text outlines the principles of motor skill learning, building a strong understanding of how skills are acquired and perfected with practice and showing students how to apply the concepts to a variety of real-world settings. Incorporating familiar scenarios brings the material to life for students, leading to better retention of information and greater interest in practical application of motor performance and learning in their everyday lives and future careers.

The fifth edition of "Motor Learning and Performance" features a more streamlined organization, with practice situations integrated directly into chapters rather than appearing at the end of the text, facilitating a stronger link between principles derived from research and practical applications. The addition of author Timothy Lee adds a fresh perspective to the text. Other key changes include the following:

- An improved web study guide offers a principles-to-application exercise and multiple interactive activities for each chapter, ensuring that students will be able to transfer core content from the book to various applied settings.

- A full-color interior provides a more engaging presentation.

- Focus on Research and Focus on Application sidebars deliver more detailed research information and make connections to real-world applications in areas such as teaching, coaching, and therapy.

- Updates to instructor ancillaries feature the addition of lab activities to the instructor guide and new chapter quizzes that assess students' mastery of the most important concepts covered in the textbook.

- Pedagogical aids such as learning objectives, glossary of terms, and Check Your Understanding questions throughout help students stay on track with learning in each chapter.

"Motor Learning and Performance, Fifth Edition," provides optimal student comprehension, offering a strong conceptual understanding of skills and then building on this with the intricacies of skilled motor performance. Part I investigates the principles of human performance, progressively developing a conceptual model of human actions. The focus is mainly on human performance as based on an information-processing perspective. In part II, the text uses the conceptual model to impart an understanding of human motor learning processes. The presentation style remains simple and straightforward for those without extensive backgrounds in motor performance.

The fifth edition of "Motor Learning and Performance: From Principles to Application" goes beyond simply presenting research, challenging students not only to grasp but also to apply the fundamental concepts of motor performance and learning. The fifth edition is a valuable tool for anyone who appreciates high-level skilled activity or would like to learn more about how such performances occur.

'Dr Anna Dixon has written a must-read for anyone interested in the future of ageing. Learn from one of the best informed about an issue, and opportunity, that is facing us all.' Andy Briggs, Head of FTSE 100 life insurer Phoenix Group 'A very important book' Sir Muir Gray The Age of Ageing Better? takes a radically different view of what our ageing society means. Dr Anna Dixon turns the misleading and depressing narrative of burden and massive extra cost of people living longer on its head and shows how our society could thrive if we started thinking differently. This book shines a spotlight on how as a society we're currently failing to respond to the shifting age profile - and what needs to change. Examining key areas of society including health, financial security, where and how people live, and social connections, Anna Dixon presents a refreshingly optimistic vision for the future that could change the way we value later life in every sense.

The honest, compassionate and vital guide to getting older, from dementia to finances, medication to care homes 'The most important book about the second half of your life you'll ever read. I wish everyone in the UK could be under Dr Lucy's care' SANDI TOKSVIG 'This warm and compassionate book gets to the heart of older age' THE BRITISH GERIATRICS SOCIETY ________ Now more than ever, we need to talk about getting older. Many of us are living to a very great age. But how do we give those we love, and eventually ourselves, long lives that are as happy and healthy as possible? Dr Lucy's book gives us answers to the questions we can voice - and those that we can't. This essential guide will guide you through those important conversations around growing older, answering every question you might have, including: * How do we start the conversation? * How do we ask whether it's worth taking seven different medicines? * Is it normal to find you're falling out of love with someone, as they disappear into dementia? * Should Dad be driving, and if not, who can stop him? * What are the secrets of the best care homes? * When does fierce independence become bad behaviour? * How do you navigate near-impossible discussions around resuscitation and intensity of treatments? * And who decides what happens when we become ill? Serious, funny, kind and knowledgeable, this readable book helps guide us through essential conversations about getting older that go straight to the heart of what matters most.

University Success Oral Communication is designed for English language learners preparing for mainstream academic environments. A flexible three-part approach includes intensive and systematic skill development tied to learning outcomes along with authentic lectures delivered by top professors from Stanford University. The Oral Communication strand provides real-life learning experiences for students who need to achieve academic autonomy. - Each part is a self-contained module allowing teachers to focus on the highest-value skills and content. Topics are aligned around science, technology, engineering, arts, and mathematics (STEAM) content. - Parts 1 and 2 include short lectures and classroom discussions that allow students to build their essential listening, speaking, and critical thinking skills. - Part 3 includes authentic extended lectures that enable students to apply and expand the skills acquired in Parts 1 and 2. - Additional online lectures, skill and vocabulary practices, collaboration activities, and assessments. - Strategies for academic success and soft skills delivered via online videos. - NEW! You can now create unique custom University Success content packs with Pearson Collections

Humans and flies look nothing alike, yet their genetic circuits are remarkably similar. Here, Lewis I. Held, Jr compares the genetics and development of the two to review the evidence for deep homology, the biggest discovery from the emerging field of evolutionary developmental biology. Remnants of the operating system of our hypothetical common ancestor 600 million years ago are compared in chapters arranged by region of the body, from the nervous system, limbs and heart, to vision, hearing and smell. Concept maps provide a clear understanding of the complex subjects addressed, while encyclopaedic tables offer comprehensive inventories of genetic information. Written in an engaging style with a reference section listing thousands of relevant publications, this is a vital resource for scientific researchers, and graduate and undergraduate students.

From the author of the New York Times bestseller The Plant Paradox comes a groundbreaking plan for living a long, healthy, happy life. From the moment we are born, our cells begin to age. But aging does not have to mean decline. World-renowned surgeon Dr. Steven Gundry has been treating mature patients for most of his career. He knows that everyone thinks they want to live forever, until they hit middle age and witness the suffering of their parents and even their peers. So how do we solve the paradox of wanting to live to a ripe old age-but enjoy the benefits of youth? This groundbreaking book holds the answer. Working with thousands of patients, Dr. Gundry has discovered that the "diseases of aging" we most fear are not simply a function of age; rather, they are a byproduct of the way we have lived over the decades. In The Longevity Paradox, he maps out a new approach to aging well-one that is based on supporting the health of the "oldest" parts of us: the microorganisms that live within our bodies. Our gut bugs-the bacteria that make up the microbiome-largely determine our health over the years. From diseases like cancer and Alzheimer's to common ailments like arthritis to our weight and the appearance of our skin, these bugs are in the driver's seat, controlling our quality of life as we age. The good news is, it's never too late to support these microbes and give them what they need to help them-and you-thrive. In The Longevity Paradox, Dr. Gundry outlines a nutrition and lifestyle plan to support gut health and live well for decades to come. A progressive take on the new science of aging, The Longevity Paradox offers an action plan to prevent and reverse disease as well as simple hacks to help anyone look and feel younger and more vital.

The Sunday Times Top Ten Bestseller TV and radio presenter Kate Garraway has a lot on her mind. She's turned 50, and suddenly seems to have MANY questions about EVERYTHING. Should she get plastic surgery? Will the menopause ruin her life? What's the secret to making love last? Can anyone really deal with the idea of death? And why, oh why, did nobody tell her how important big knickers would be?! As she tries to find what's useful amongst the deluge of advice we are bombarded with, Kate discovers a lesson on why women in their midlife and beyond should be loved and celebrated, especially by themselves...

In Skeleton Keys: An Introduction to Human Skeletal Morphology, Development, and Analysis, Second Edition, Jeffrey H. Schwartz presents a detailed yet highly accessible introduction to the study of the human skeleton. This unique volume examines the skeleton from its developmental basis to the expression of individual variation. It reviews a variety of different approaches used to determine an individual's sex, age, and pathological history and challenges readers to think critically about how to analyze a human skeleton rather than learning formulas for quick results. An ideal text for courses in human osteology, skeletal analysis, and bioarchaeology, this book is also a helpful reference for professionals.
Thoroughly revised and updated, the second edition of Skeleton Keys features:
* A unique CD-ROM containing hundreds of color images of skeletons and skeletal elements--demonstrating morphology, pathology, and nonmetric variation--that can be used as classroom projections or for individual study
* Coverage of the most recent developments in the field, including the molecular regulation of bone and tooth formation
* Expanded studies in each area of analysis: sex, age, nonmetric variation, pathology, biodistance and bioarchaeology, and stable isotope analysis
* Additional photographic images, especially in the pathology and sexing chapters
* Two separate and extensively illustrated chapters on the skull, one dealing with articulated elements and one with isolated bones (these topics were covered in one chapter in the first edition)
* Integration of material--such as anthropometric landmarks--from appendices in the previous edition into relevant chapters astables
* More accessible language throughout and an extensive glossary

The second edition of "Growth, Maturation, and Physical Activity" has been expanded with almost 300 new pages of material, making it the most comprehensive text on the biological growth, maturation, physical performance, and physical activity of children and adolescents. The new edition retains all the best features of the original text, including the helpful outlines at the beginning of each chapter that allow students to review major concepts.

This edition features updates on basic content, expanded and modified chapters, and the latest research findings to meet the needs of upper undergraduate and graduate students as well as researchers and professionals working with children and young adults. The second edition also includes these new features:

-10 lab activities that encourage students to investigate subject matter outside of class and save teachers time

-A complete reference list at the end of each chapter

-Chapter-ending summaries to make the review process easy for students

-New chapters that contain updates on thermoregulation, methods for the assessment of physical activity, undernutrition, obesity, children with clinical conditions, and trends in growth and performance

-Discussions that span current problems in public health, such as the quantification of physical activity and energy expenditure, persistent undernutrition in developing countries, and the obesity epidemic in developed countriesThe authors are three of the world's foremost authorities on children's growth and development. In 29 chapters, they address introductory concepts and prenatal growth, postnatal growth, functional development, biological maturation, influencing factors in growth, maturation and development, and specific applications to public health and sport. In addition, secular trends in growth, maturation, and performance over the past 150 years are considered. You'll be able to recognize risk factors that may affect young athletes; you'll also be able to make informed decisions about appropriate physical activities, program delivery, and performance expectations.

"Growth, Maturation, and Physical Activity, Second Edition, " covers many additional topics, including new techniques for the assessment of body composition, the latest advances in the study of skeletal muscle, the human genome, the hormonal regulation of growth and maturation, clarification of dietary reference intakes, and the study of risk factors for several adult diseases.

This is the only text to focus on the biological growth and maturation process of children and adolescents as it relates to physical activity and performance. With over 300 new pages of material, this text expertly builds on the successful first edition.

For developmental scientists, the nature versus nurture debate has been settled for some time. Neither nature nor nurture alone provides the answer. It is nature and nurture in concert that shape developmental pathways and outcomes, from health to behavior to competence. This insight has moved far beyond the assertion that both nature and nurture matter, progressing into the fascinating terrain of how they interact over the course of development. In this volume, students, practitioners, policy analysts, and others with a serious interest in human development will learn what is transpiring in this new paradigm from the developmental scientists working at the cutting edge, from neural mechanisms to population studies, and from basic laboratory science to clinical and community interventions. Early childhood development is the critical focus of this volume, because many of the important nature-nurture interactions occur then, with significant influences on lifelong developmental trajectories.

Inherited disorders of the kidney are becoming important, not only in pediatric nephrological practice, but also in adult nephrology, representing a high proportion of patients with end-stage renal failure. In almost 50% of all children and in 15% of adults accepted for renal replacement therapy, the causative disorders have a hereditary basis. Many of these disorders are apparent at birth but may not cause renal failure until adolescence. Others may not present until adult life. The contribution of these disorders to adult nephrological practice has so far been understated in most of the existing textbooks. This book presents a practical approach to the investigation and management of patients with inherited renal disorders. The book is aimed at both established pediatric and adult nephrologists, as well as nephrologists in training, and will also be of interest to pediatricians, geneticists, and research workers in this field.

For developmental scientists, the nature versus nurture debate has been settled for some time. Neither nature nor nurture alone provides the answer. It is nature and nurture in concert that shape developmental pathways and outcomes, from health to behavior to competence. This insight has moved far beyond the assertion that both nature and nurture matter, progressing into the fascinating terrain of how they interact over the course of development. In this volume, students, practitioners, policy analysts, and others with a serious interest in human development will learn what is transpiring in this new paradigm from the developmental scientists working at the cutting edge, from neural mechanisms to population studies, and from basic laboratory science to clinical and community interventions. Early childhood development is the critical focus of this volume, because many of the important nature-nurture interactions occur then, with significant influences on lifelong developmental trajectories.

In this novel examination of the issue of abortion, the authors offer a primer in the biological aspects of fetal development and its impact on the abortion controversy. Although purely scientific study cannot offer a universal solution to the issue of abortion, nor can a purely political or moral response be fully informed without the benefit of the latest scientific knowledge.

Reviewing the latest developments in molecular biology, evolutionary biology, embryology, and neurophysiology, the authors reveal a surprising agreement of scientific opinion on when 'humanness' begins: with the development of a highly developed cerebral cortex. It is on this issue that the authors focus with sensitivity to the myriad of ethical and religious arguments that surround it.

The University of Florida has an ambitious goal: to harness the power of its faculty, staff, students, and alumni to solve some of society's most pressing problems and to become a resource for the state of Florida, the nation, and the world. In the upcoming decades, an unprecedented demographic shift will take place; the eighty-five and over population is projected to climb far higher than any other age group. To keep the current elderly population healthy and help prevent future generations from experiencing poor health outcomes, researchers are studying crucial connections between skeletal muscles and whole-body health. The University of Florida is at the forefront of this research, utilizing its nationally recognized excellence in the fields of muscle biology and exercise physiology to discover unique ways to preserve muscle health in the aging and those with diseases. Find out how the proteins within muscle can be manipulated to reduce recovery times for individuals who are bedridden. Learn how older, elite athletes have resisted the inevitable degeneration that comes with aging, and how intermittent fasting may help you live longer and healthier. Step inside the lab where a researcher is uncovering the origins of cancer cachexia a wasting syndrome responsible for 20 percent of cancer deaths worldwide to improve the lives of patients. The loss of skeletal muscle through disease, disuse, or aging is associated with a host of poor health outcomes, but promising new avenues of research are being studied every day at the University of Florida to make for a healthier tomorrow.