The effects of the bone morphogenetic proteins (BMPs) family on bone formation are well documented, but the transforming growth factor (TGF)-beta ( ) isoforms are much less studied. The product of 20 years of study, Induction of Bone Formation in Primates: The Transforming Growth Factor- 3 sums up editor Ugo Ripamonti's research into the osteogenic activity of the three mammalian TGF- isoforms, particularly in primates. It explores how the mammalian TGF- isoforms have the potential to shed light on the apparent redundancy of bone induction signaling. The book unearths the profound and important bone inductive activity of the TGF- 3 isoform. It includes accounts of extensive research in non-human primates from craniofacial tissue regeneration, heterotopic tissue induction, and chapters on periodontal tissue regeneration and synergistic induction of bone formation. It also discusses the future clinical role of the TGF- isoform, including in human studies. This book contributes to the fascinating history of BMP and TGF- research at the intersection of molecular biology, tissue induction, bone regeneration, and craniofacial surgery. It provides a revolutionary awakening to new possibilities in skeletal reconstruction, tissue engineering, and molecular and cellular biology.

In Neurosis and Human Growth, Dr. Horney discusses the neurotic process as a special form of the human development, the antithesis of healthy growth. She unfolds the different stages of this situation, describing neurotic claims, the tyranny or inner dictates and the neurotic's solutions for relieving the tensions of conflict in such emotional attitudes as domination, self-effacement, dependency, or resignation. Throughout, she outlines with penetrating insight the forces that work for and against the person's realization of his or her potentialities. First Published in 1950. Routledge is an imprint of Taylor & Francis, an informa company.

This book examines driver, vehicle, roadway and environmental characteristics associated with increased crash involvement by older drivers. Project activities were designed to prioritise the situations causing problems for older drivers based on the magnitude of the crash problem, older driver's degree of over-representation, the likelihood of serious injury, or other criteria of interest. The resulting list of the most problematic situations frame further discussions of how age-related functional decline can mediate increased crash risk for older drivers, and hopefully, point to potential countermeasures for lowering this risk.

In Skeleton Keys: An Introduction to Human Skeletal Morphology, Development, and Analysis, Second Edition, Jeffrey H. Schwartz presents a detailed yet highly accessible introduction to the study of the human skeleton. This unique volume examines the skeleton from its developmental basis to the expression of individual variation. It reviews a variety of different approaches used to determine an individual's sex, age, and pathological history and challenges readers to think critically about how to analyze a human skeleton rather than learning formulas for quick results. An ideal text for courses in human osteology, skeletal analysis, and bioarchaeology, this book is also a helpful reference for professionals.
Thoroughly revised and updated, the second edition of Skeleton Keys features:
* A unique CD-ROM containing hundreds of color images of skeletons and skeletal elements--demonstrating morphology, pathology, and nonmetric variation--that can be used as classroom projections or for individual study
* Coverage of the most recent developments in the field, including the molecular regulation of bone and tooth formation
* Expanded studies in each area of analysis: sex, age, nonmetric variation, pathology, biodistance and bioarchaeology, and stable isotope analysis
* Additional photographic images, especially in the pathology and sexing chapters
* Two separate and extensively illustrated chapters on the skull, one dealing with articulated elements and one with isolated bones (these topics were covered in one chapter in the first edition)
* Integration of material--such as anthropometric landmarks--from appendices in the previous edition into relevant chapters astables
* More accessible language throughout and an extensive glossary

Diana Moran, aka The Green Goddess, is here to help spread the word about treatments and preventative measures we can all take to tackle osteoporosis. As a sufferer of osteopenia herself (an early form of osteoporosis) Diana Moran is a strong advocate for exercise, early diagnosis, weight bearing exercise, vitamin D and other measures that can be taken to tackle osteoporosis. Written in association with the Royal Osteoporosis Society, this practical book is a must-have for anybody affected by osteoporosis. Packed with advice, friendly tips and ideas, and an overview of current research, and what we can all be doing to help ourselves live well. Also contains specially designed exercises to help encourage a more active lifestyle and strengthen areas of weakness, alongside the important theory, and medical side of osteoporosis. This is an easy to digest, friendly guide for the general reader.

The world's foremost expert shares advice on later-in-life ADHD, tackling everything from finances, parenting, planning for retirement, social life and work, in this practical and helpful guide for those with and without a diagnosis. Do you... · Forget to pay bills? · Live in a disorganised environment? · Struggle with mental health? · Procrastinate on projects, even ones that initially excite you? · Have high levels of conflict with those close to you? · Have a child diagnosed with ADHD and/or a family history of learning disorders? If some of these patterns sound familiar, you might understandably fear the onset of dementia, but you may have undiagnosed attention deficit hyperactivity disorder (ADHD). ADHD in adults is one of the most common disorders. Living with ADHD in our later years is hugely influenced by co-occurring issues, such as anxiety, depression or low self-esteem. In addition, the presence of learning disorders, heightened levels of stress, the presence or lack of support from others, and the number of people we are responsible for, can all complicate and intensify the effects of ADHD. The good news is that you've come to the right place to learn more about how to lead a calmer, happier, more productive life. Dedicated to the health and wellbeing of today's older adults with ADHD, Still Distracted After All These Years offers strategies to build a support system, gain better control over your daily life and create a more ADHD-friendly retirement.

Inherited disorders of the kidney are becoming important, not only in pediatric nephrological practice, but also in adult nephrology, representing a high proportion of patients with end-stage renal failure. In almost 50% of all children and in 15% of adults accepted for renal replacement therapy, the causative disorders have a hereditary basis. Many of these disorders are apparent at birth but may not cause renal failure until adolescence. Others may not present until adult life. The contribution of these disorders to adult nephrological practice has so far been understated in most of the existing textbooks. This book presents a practical approach to the investigation and management of patients with inherited renal disorders. The book is aimed at both established pediatric and adult nephrologists, as well as nephrologists in training, and will also be of interest to pediatricians, geneticists, and research workers in this field.

In this novel examination of the issue of abortion, the authors offer a primer in the biological aspects of fetal development and its impact on the abortion controversy. Although purely scientific study cannot offer a universal solution to the issue of abortion, nor can a purely political or moral response be fully informed without the benefit of the latest scientific knowledge.

Reviewing the latest developments in molecular biology, evolutionary biology, embryology, and neurophysiology, the authors reveal a surprising agreement of scientific opinion on when 'humanness' begins: with the development of a highly developed cerebral cortex. It is on this issue that the authors focus with sensitivity to the myriad of ethical and religious arguments that surround it.

The question of whether abortion should or should not be permitted, and under what circumstances, is among the most difficult and sometimes anguished decisions for contemporary men and women. How we feel about this issue, and what actions we take, help to define our image of who we are as social beings. In the midst of the surrounding political, ethical, and religious debate, people everywhere are once again examining their conscience and their beliefs, and turning to unutilized sources of information as they seek to come to terms with this contentious issue. And as emotions run high, it is helpful to step back from the highly charged arena to reconsider the underlying scientific facts about human development.
In The Facts of Life, Harold Morowitz and James Trefil, two distinguished scientists and science writers, examine what modern biology can contribute to our understanding of this debate. Sensitive to the myriad ethical and religious arguments beyond the realm of science that swirl around abortion, the authors focus on one crucial question--when does a fetus acquire "humanness," that quality that sets us apart from all other living things. From the viewpoint of science, they argue, "humanness" begins with the possession of a highly developed cerebral cortex. While humans are linked via cell structure and cell chemistry with all life on our planet--from monkeys to fruit flies to pumpkins--it is the human brain structure which makes us who we are. Reviewing the latest advances in molecular biology, evolutionary biology, embryology, neurophysiology, and neonatology--fields that all bear on this question--the authors reveal a surprising consensus of scientific opinion on when humanness begins.
A lucid primer on the biological aspects of the abortion issue, The Facts of Life is also a fascinating inquiry, across various scientific disciplines, into what makes us uniquely human. Anyone who struggles with the issue of abortion will be grateful to find a work that moves this heated issue from the intensely emotional area it has occupied to the calmer domain of science.

This new volume outlines methods of monitoring growth and weight gain, an essential clinical service. The alternative methods described here will be of particular use to workers in Third World countries where the cost of scales as well as illiteracy and cultural differences make weight-plotting especially difficult. Readers will find outlines of such innovative methods as the use of arm growth tape, simplified techniques of weight plotting, and helpful algorithms for decision-making. Among the book's appendices is a point system for comparative evaluation of weighing scales. Many illustrations help clarify the material presented in the text, making this book valuable in the classroom as well as in the field.

This text provides an interesting and informative account of the child's journey from the womb to the world outside, through childhood and into adolescence. It is based on the belief that it is vital for those training to work with children who have problems to understand what is typical or atypical in children's development.

The first half of the book, discussing normal patterns of growth and development, is cross-referenced to equivalent chapters in the second half, which discuss the atypical route. These connections serve to emphasize the continuities between, and similarities of, children with typical and atypical conditions. Among the difficulties covered are:
Pervasive developmental disorders
Genetic disorders
Physical impairments
Learning difficulties
Brain damage
Emotional and behavioural disorders
Personality disorders.
Physical and mental illnesses

The text also deliberately links developmental and clinical psychology approaches in order to help readers connect their theoretical understanding of the physical and psychological problems of childhood with the practicalities of assessment, rehabilitation and treatment.

University Success Oral Communication is designed for English language learners preparing for mainstream academic environments. A flexible three-part approach includes intensive and systematic skill development tied to learning outcomes along with authentic lectures delivered by top professors from Stanford University. The Oral Communication strand provides real-life learning experiences for students who need to achieve academic autonomy. - Each part is a self-contained module allowing teachers to focus on the highest-value skills and content. Topics are aligned around science, technology, engineering, arts, and mathematics (STEAM) content. - Parts 1 and 2 include short lectures and classroom discussions that allow students to build their essential listening, speaking, and critical thinking skills. - Part 3 includes authentic extended lectures that enable students to apply and expand the skills acquired in Parts 1 and 2. - Additional online lectures, skill and vocabulary practices, collaboration activities, and assessments. - Strategies for academic success and soft skills delivered via online videos. - NEW! You can now create unique custom University Success content packs with Pearson Collections

This authoritative reference work contains more than 300 entries covering all aspects of the multi-disciplinary field of adult development and aging Brings together concise, accurate summaries of classic topics as well as the most recent thinking and research in new areas Covers a broad range of issues, from biological and physiological changes in the body to changes in cognition, personality, and social roles to applied areas such as psychotherapy, long-term care, and end-of-life issues Includes contributions from major researchers in the academic and clinical realms 3 Volumes www.encyclopediaadulthoodandaging.com

A deliciously funny and sage guide to midlife - an unscientific, flaws-and-all account of one woman's adventures and misadventures through the dark comedy of the wilderness years. Through her own experiences as a fifty-something woman, and those of her three sisters, her indomitable mum and rebellious auntie, Charlotte tackles the big questions every woman seeks answers to at this time of our lives - chiefly: How the hell am I going to get over being young in a world obsessed with youth? Written with warmth, wisdom and irreverence this guide to midlife is perfect for readers of Nora Ephron, Caitlin Moran and India Knight.

Sugden and Wade, leading authors in this area, comprehensively cover motor development and motor impairment, drawing on sources in medicine and health-related studies, motor learning and developmental psychology. A theme that runs through the book is that movement outcomes are a complex transaction of child resources, the context in which movement takes place, and the manner in which tasks are presented. The core themes of the book involve descriptions of motor development from conception through to emerging adulthood, explanations of motor development from differing theoretical, empirical, and experiential perspectives, and descriptions and explanations of atypical motor development when the resources of the child are limited in some way. Readership: Occupational therapists, physiotherapists, paediatricians, teachers (physical education, early childhood development, elementary education), educational psychologists, kinesiology and sports scientists.

Developmental theorists have struggled with defining the relations among biology, psychology, and sociocultural context, often reducing psychological functions of a person to either biological functioning or the role of sociocultural context - nature or nurture - and considering each area of human development separately. New Perspectives on Human Development addresses fundamental questions of development with a unified approach. It encompasses theory and research on cognitive, social and moral, and language and communicative development, in various stages of life, and explores interdisciplinary perspectives. New Perspectives on Human Development revisits old questions and applies original empirical findings, offering new directions for future research in the field.

Lifespan Development: Biopsychosocial Perspectives provides students with complete explorations of each developmental stage of the lifespan, beginning with conception and concluding with an examination of successful aging. The book presents human development theory and research within a biopsychosocial framework, presenting information regarding biological, psychological, and social functioning during each significant period of the lifespan. The first chapter of the text presents readers with an introduction to human development, addressing the meaning of age and aging, the four key principles of human development, the social factors that influence the study of human development, and more. The succeeding chapters progress in step with the human lifespan, beginning with conception and prenatal development, moving through infancy, childhood, adolescence, and adulthood, and concluding with chapters devoted to later life. The biopsychosocial perspective of the text emphasizes the transactional nature of biological, psychological, and social influences on the developing individual with a focus on positive development and the implications on health and wellness. It emphasizes the applied nature of the biopsychosocial perspective. Each chapter begins with a real-life scenario, challenging students to take the perspectives of individuals and practitioners dealing with issues at every stage of development. Designed to provide readers with a holistic understanding of the complex progression of human life and aging, Lifespan Development is an ideal text for courses in psychology and human development.

Humans and flies look nothing alike, yet their genetic circuits are remarkably similar. Here, Lewis I. Held, Jr compares the genetics and development of the two to review the evidence for deep homology, the biggest discovery from the emerging field of evolutionary developmental biology. Remnants of the operating system of our hypothetical common ancestor 600 million years ago are compared in chapters arranged by region of the body, from the nervous system, limbs and heart, to vision, hearing and smell. Concept maps provide a clear understanding of the complex subjects addressed, while encyclopaedic tables offer comprehensive inventories of genetic information. Written in an engaging style with a reference section listing thousands of relevant publications, this is a vital resource for scientific researchers, and graduate and undergraduate students.

Humans and flies look nothing alike, yet their genetic circuits are remarkably similar. Here, Lewis I. Held, Jr compares the genetics and development of the two to review the evidence for deep homology, the biggest discovery from the emerging field of evolutionary developmental biology. Remnants of the operating system of our hypothetical common ancestor 600 million years ago are compared in chapters arranged by region of the body, from the nervous system, limbs and heart, to vision, hearing and smell. Concept maps provide a clear understanding of the complex subjects addressed, while encyclopaedic tables offer comprehensive inventories of genetic information. Written in an engaging style with a reference section listing thousands of relevant publications, this is a vital resource for scientific researchers, and graduate and undergraduate students.

The age-friendly community movement is a global phenomenon, currently growing with the support of the WHO and multiple international and national organizations in the field of aging. Drawing on an extensive collection of international case studies, this volume provides an introduction to the movement. The contributors - both researchers and practitioners - touch on a number of current tensions and issues in the movement and offer a wide-ranging set of recommendations for advancing age-friendly community development. The book concludes with a call for a radical transformation of a medical and lifestyle model of aging into a relational model of health and social/individual wellbeing.

Too tiny to see with the naked eye, the human embryo was just a hypothesis until the microscope made observation of embryonic development possible. This changed forever our view of the minuscule cluster of cells that looms large in questions about the meaning of life. Embryos under the Microscope examines how our scientific understanding of the embryo has evolved from the earliest speculations of natural philosophers to today's biological engineering, with its many prospects for life-enhancing therapies. Jane Maienschein shows that research on embryos has always revealed possibilities that appear promising to some but deeply frightening to others, and she makes a persuasive case that public understanding must be informed by up-to-date scientific findings. Direct observation of embryos greatly expanded knowledge but also led to disagreements over what investigators were seeing. Biologists confirmed that embryos are living organisms undergoing rapid change and are not in any sense functioning persons. They do not feel pain or have any capacity to think until very late stages of fetal development. New information about DNA led to discoveries about embryonic regulation of genetic inheritance, as well as evolutionary relationships among species. Scientists have learned how to manipulate embryos in the lab, taking them apart, reconstructing them, and even synthesizing--practically from scratch--cells, body parts, and maybe someday entire embryos. Showing how we have learned what we now know about the biology of embryos, Maienschein changes our view of what it means to be alive.

In this worldwide survey, Clive Gamble explores the evolution of the human imagination, without which we would not have become a global species. He sets out to determine the cognitive and social basis for our imaginative capacity and traces the evidence back into deep human history. He argues that it was the imaginative ability to 'go beyond' and to create societies where people lived apart yet stayed in touch that made us such effective world settlers. To make his case Gamble brings together information from a wide range of disciplines: psychology, cognitive science, archaeology, palaeoanthropology, archaeogenetics, geography, quaternary science and anthropology. He presents a novel deep history that combines the archaeological evidence for fossil hominins with the selective forces of Pleistocene climate change, engages with the archaeogeneticists' models for population dispersal and displacement, and ends with the Europeans' rediscovery of the deep history settlement of the Earth.

Predicting water runoff in ungauged water catchment areas is vital to practical applications such as the design of drainage infrastructure and flooding defences, runoff forecasting, and for catchment management tasks such as water allocation and climate impact analysis. This full colour book offers an impressive synthesis of decades of international research, forming a holistic approach to catchment hydrology and providing a one-stop resource for hydrologists in both developed and developing countries. Topics include data for runoff regionalisation, the prediction of runoff hydrographs, flow duration curves, flow paths and residence times, annual and seasonal runoff, and floods. Illustrated with many case studies and including a final chapter on recommendations for researchers and practitioners, this book is written by expert authors involved in the prestigious IAHS PUB initiative. It is a key resource for academic researchers and professionals in the fields of hydrology, hydrogeology, ecology, geography, soil science, and environmental and civil engineering.