This book is a contemporary statement of what is known about morphological development of the normal and abnormal human nervous system and puts into perspective the continued importance of changes that occur in the course of foetal development and how these processes may become defective. The first part of the book deals with the development of the central nervous system (CNS) from a morphological point of view including data from the fields of biochemistry, immunology and genetics. The second part reviews the genetic and nongenetic etiology of abnormal CNS development and discusses throughly all patologic syndromes that are related to disturbances of brain development. With the rapid progress in such modern branches of science as neurochemistry, genetics and molecular biology, this book will be invaluable for researchers working in these fields.

Bipolar spectrum disorders are characterized by severe mood dysregulation, rage, irritability, and depression, along with low self-esteem and interpersonal struggles. Children with bipolar symptoms also tend to have poor academic performance and disruptive school behavior, and their families often experience strained relationships and increased conflict. RAINBOW: A Child- and Family-Focused Cognitive-Behavioral Treatment for Pediatric Bipolar Disorder presents a 12-session family-based treatment intervention for children aged 7-13 with bipolar spectrum disorders. The CFF-CBT/RAINBOW program comprises four innovative aspects in that it: (1) is designed to be developmentally specific to children in this age group; (2) is driven by the distinct needs of these children and their families; (3) involves intensive work with parents parallel to the work with children in order to directly address parents' own therapeutic needs, as well as helping them develop an effective parenting style for their child; and (4) integrates psychoeducation, cognitive-behavioral therapy, and interpersonal therapy techniques, tailored to the unique needs of these children, to augment the effects of pharmacotherapy. This Clinician Manual includes a conceptual overview for each session as well as step-by-step instructions for clinicians with all accompanying handouts, worksheets, and in-session games/activities. It provides clinicians with a comprehensive set of tools and a structured approach to guiding children and families. RAINBOW has been shown to significantly reduce mood symptoms and improve overall functioning for children with bipolar spectrum disorders.

Humans and flies look nothing alike, yet their genetic circuits are remarkably similar. Here, Lewis I. Held, Jr compares the genetics and development of the two to review the evidence for deep homology, the biggest discovery from the emerging field of evolutionary developmental biology. Remnants of the operating system of our hypothetical common ancestor 600 million years ago are compared in chapters arranged by region of the body, from the nervous system, limbs and heart, to vision, hearing and smell. Concept maps provide a clear understanding of the complex subjects addressed, while encyclopaedic tables offer comprehensive inventories of genetic information. Written in an engaging style with a reference section listing thousands of relevant publications, this is a vital resource for scientific researchers, and graduate and undergraduate students.

Ever wondered what's really going on in your body as you age? Can you really eat to beat cancer or prevent heart disease? These questions and more are answered in Eat Better, Live Longer, helping you make achievable, sensible, science-based changes to your diet from day one. Discover the secrets of long life from centenarians around the world, and explore the 10 simple but meaningful adaptations you can make both to what you eat and to how you eat to follow in their footsteps. A four-week eating plan, with over 110 nutrient-packed recipes, helps you learn to make smarter choices about foods that can reduce your risk of certain diseases and lessen the effects of others. Use this new-found knowledge together with details on how each part of your body changes as you age and which nutrients you need to support support all-round health, helping you live a longer, happier life. Future-proof your life with this science-based superfood approach to discovering what is really happening to your body as you are aging.

For developmental scientists, the nature versus nurture debate has been settled for some time. Neither nature nor nurture alone provides the answer. It is nature and nurture in concert that shape developmental pathways and outcomes, from health to behavior to competence. This insight has moved far beyond the assertion that both nature and nurture matter, progressing into the fascinating terrain of how they interact over the course of development. In this volume, students, practitioners, policy analysts, and others with a serious interest in human development will learn what is transpiring in this new paradigm from the developmental scientists working at the cutting edge, from neural mechanisms to population studies, and from basic laboratory science to clinical and community interventions. Early childhood development is the critical focus of this volume, because many of the important nature-nurture interactions occur then, with significant influences on lifelong developmental trajectories.

For developmental scientists, the nature versus nurture debate has been settled for some time. Neither nature nor nurture alone provides the answer. It is nature and nurture in concert that shape developmental pathways and outcomes, from health to behavior to competence. This insight has moved far beyond the assertion that both nature and nurture matter, progressing into the fascinating terrain of how they interact over the course of development. In this volume, students, practitioners, policy analysts, and others with a serious interest in human development will learn what is transpiring in this new paradigm from the developmental scientists working at the cutting edge, from neural mechanisms to population studies, and from basic laboratory science to clinical and community interventions. Early childhood development is the critical focus of this volume, because many of the important nature-nurture interactions occur then, with significant influences on lifelong developmental trajectories.

Despite the undeniable physical, psychological, and social effects of aging, most older persons cope quite well and find considerable satisfaction in their later years. Part of the explanation for this finding is based on what Robert C. Atchley calls "continuity"--the ability of older persons to maintain a strong sense of purpose and self in the face of the changes associated with aging. Continuity can help individuals evolve psychologically and socially in the presence of life events such as retirement, widowhood, and physical disability.

Atchley begins with a thorough explanation of continuity theory, identifying important methodological considerations in its evaluation and use. He then looks at evidence for continuity over time in the ways individuals interpret their experiences and make decisions regarding their living arrangements and lifestyles. He examines continuity as a personal goal that most people use to guide their development as individuals. Atchley finds that many aging adults add transcendence as a personal goal in later adulthood. In a concluding chapter, he revisits the basic elements of continuity theory, summarizing the evidence that supports it.

Drawing on data from a twenty-year longitudinal study that began with more than 1,200 individuals, "Continuity and Adaptation in Aging" explains one of the primary underlying forces that promotes effective adaptation to the aging process. This book will be of interest to researchers and students in gerontology and adult development.

A delicious way to hack your DNA and prevent early aging While some enjoy extremely active and healthy lives as they age, others spend years of their life burdened by heart disease, dementia, and other age-related diseases. Until recently, this was often chalked up to luck or "good genes." But fascinating new research suggests that telomeres, the protective caps on your chromosomes, are actually directly linked to aging. Telomeres, when protected, can lead to a longer, happier life. Fortunately, one of the key components to protecting your telomeres is a balanced diet. The Telomere Diet and Cookbook is the first book to offer an easy-to-read, targeted overview of telomeres and nutrition. Including detailed meal plans and shopping lists, this book offers a simple step-by-step starter program and over 75 delicious recipes.

This book focuses on four of the hallmarks of aging: aspartic acid racemization, advanced glycation end products, telomere shortening and mitochondrial mutations; describing their role in aging and diseases; and their application to age-at-death estimation in forensic sciences in greater depth, displaying the interconnecting pathways among these processes. An additional chapter related to Epigenetics and its role in aging, diseases, and forensic age estimation is also included. This book is aimed at a broad audience: from students being introduced to aging, diseases, and forensic science research to scientists in biomedicine and forensics complementing their knowledge in their respective fields while also increasing their knowledge in other disciplines.

Master the effective evaluation, analysis and management of placental-fetal growth restriction (PFGR), developing strategies to reduce the risk of perinatal mortality and morbidity in patients worldwide. Extensively researched by international experts, this manual provides practitioners with a detailed, hands-on approach to the practical 'pearls' for direct patient management. This authoritative volume advises on matters such as the correct evaluation and management of high-risk patients in danger of PFGR through to delivery. Extensive and wide-ranging, this book is an invaluable companion to the developing research interest and clinical applications in PFGR, including developmental outcomes in early childhood. Featuring a critical evaluation of a variety of abnormal conditions, such as fetal hypoxia and extreme prematurity, which are clearly displayed through extensive illustrations, this essential toolkit ensures that practitioners at all levels can effectively limit adverse outcome and reach the correct diagnosis.

"Advanced Analysis of Motor Development" explores how research is conducted in testing major issues and questions in motor development. It also looks at the evolution of research in the field, its current status, and possible future directions. This text is one of the few to examine motor development models and theories analytically while providing a context for advanced students in motor development so they can understand current and classic research in the field.

Traditionally, graduate study in motor development has been approached through a compilation of readings from various sources. This text meets the need for in-depth study in a more cohesive manner by presenting parallels and highlighting relationships among research studies that independent readings might not provide. In addition, "Advanced Analysis of Motor Development" builds a foundation in the theories and approaches in the field and demonstrates how they drive contemporary research in motor development.

A valuable text for graduate students beginning their own research projects or making the transition from student to researcher, this text focuses on examining and interpreting research in the field. Respected researchers Haywood, Roberton, and Getchell explain the history and evolution of the field and articulate key research issues. As they examine each of the main models and theories that have influenced the field, they share how motor development research can be applied to the fields of physical education, special education, physical therapy, and rehabilitation sciences.

With its emphasis on critical inquiry, "Advanced Analysis of Motor Development" will help students examine important topics and questions in the field in a more sophisticated manner. They will learn to analyze research methods and results as they deepen their understanding of developmental phenomena. For each category of movement skills covered (posture and balance, foot locomotion, ballistic skills, and manipulative skills), the authors first offer a survey of the pertinent research and then present an in-depth discussion of the landmark studies. In analyzing these studies, students will come to appreciate the detail of research and begin to explore possibilities for their own future research. Throughout the text, special elements help students focus on analysis. Tips for Novice Researchers sidebars highlight issues and questions raised by research and offer suggestions for further exploration and study. Comparative tables detail the differences in the purpose, methods, and results of key studies to help students understand not only what the studies found but also the relevance of those findings.

With "Advanced Analysis of Motor Development," readers will discover how research focusing on the major issues and central questions in motor development is produced and begin to conceptualize their own research. Readers will encounter the most important models and theories; dissect some of the seminal and recent articles that test these models and theories; and examine issues such as nature and nurture, discontinuity and continuity, and progression and regression. "Advanced Analysis of Motor Development" will guide students to a deeper understanding of research in life span motor development and enable them to examine how the complexities of motor development can be addressed in their respective professions.

This compilation arises from contributions made to the seventh postgraduate course in paediatric neurology held in Pavia, Italy under the auspices of the Mariani Foundation in co-operation with the National Neurologic Institute of Milan. The course concentrated on three main areas: the impact of molecular biology and molecular genetics on aetiology, advances in our understanding pathogenesis, and finally therapy. The choice of the subject was suggested by the remarkable progress has been made in this field during the last decade, mostly due to the recent advances in genetics which now enable a new nosographic approach as well as different diagnostic strategies. Part of this work is dedicated to the rehabilitation of patients affected by neuromuscular diseases.

Lifespan Development: Biopsychosocial Perspectives provides students with complete explorations of each developmental stage of the lifespan, beginning with conception and concluding with an examination of successful aging. The book presents human development theory and research within a biopsychosocial framework, presenting information regarding biological, psychological, and social functioning during each significant period of the lifespan. The first chapter of the text presents readers with an introduction to human development, addressing the meaning of age and aging, the four key principles of human development, the social factors that influence the study of human development, and more. The succeeding chapters progress in step with the human lifespan, beginning with conception and prenatal development, moving through infancy, childhood, adolescence, and adulthood, and concluding with chapters devoted to later life. The biopsychosocial perspective of the text emphasizes the transactional nature of biological, psychological, and social influences on the developing individual with a focus on positive development and the implications on health and wellness. It emphasizes the applied nature of the biopsychosocial perspective. Each chapter begins with a real-life scenario, challenging students to take the perspectives of individuals and practitioners dealing with issues at every stage of development. Designed to provide readers with a holistic understanding of the complex progression of human life and aging, Lifespan Development is an ideal text for courses in psychology and human development.

As an objective of human security, it is important to understand the social system and to make more appropriate policies for people based on the bio-psycho-social viewpoint of health advocated by the World Health Organization (WHO). For countries with increasingly large populations of older adults, aging-related disorders cause many social handicaps. A comprehensive approach for integrating not only medical, but also psychosocial and spiritual viewpoints is needed for better health policy planning.During a risky situation such as a major disaster, which can critically affect peoples lives, people should utilize their brains more fully in order to survive; i.e., to understand the situation around them, to make a proper judgment call, and to choose their behaviors. All of these approaches are associated with brain functions. Understanding the situation primarily requires the posterior part of the brain, especially the parietal lobe.Briefly, the occipital, temporal, parietal, and frontal lobes are related to visual, auditory, other sensory, and motor functions, respectively. Each lobe has primary and secondary areas: The former is associated with primary function, whereas the latter is related to association functions, which add meaning to the primary information. In particular, visual and auditory information should be fully integrated to understand the situation and make a judgment call, which is the function of the parietal lobe.Human Security: Social Support for the Health of an Aging Population Based on Geriatric Behavioral Neurology is meant to help readers understand the bio-psycho-social viewpoint and bioethics of social support for elderly people. The second aim is to understand the social support system and Quality of Life (QOL) for handicapped and elderly people. Especially, the long-term care insurance system for elderly people in Japan, which is a well-organized system to support well-being in the elderly, needs to be understood. Also, dementia is one of the important age-related disorders that can affect not only patients themselves, but also their families, community residents, and society. The third objective is to understand dementia and dementing diseases, not only from a medical perspective, but in terms of psychosocial and spiritual aspects. Following the Great East Japan Earthquake of 2011, various cases of weakness due to the disaster were analyzed. Most of them were previously assessed as a borderline condition between healthy and dementia. Therefore, it is important to routinely screen community residents for security.All risky situations such as a disaster should be treated internationally. The author recalls that one student told them that the Indonesian government faces difficulties in preparing for a disaster with a unified language. Indeed, more than 700 regional languages are spoken in Indonesias numerous islands. However, disasters do not select a language. The author is certain that there are some lessons from their history that have not been recorded in a common language. It is important to establish a network based not only on local culture and language, but also a global proposal based on a common language.The author hopes that young scientists in the next generation will have an integrated perspective and will apply science to human security worldwide.