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Books > Medicine > Pre-clinical medicine: basic sciences > Human reproduction, growth & development > Human growth & development
This second edition of the Handbook of Communication and Aging Research captures the ever-changing and expanding domain of aging research. Since it was first recognized that there is more to social aging than demography, gerontology has needed a communication perspective. Like the first edition, this handbook sets out to demonstrate that aging is not only an individual process but an interactive one. The study of communication can lead to an understanding of what it means to grow old. We may age physiologically and chronologically, but our social aging--how we behave as social actors toward others, and even how we align ourselves with or come to understand the signs of difference or change as we age--are phenomena achieved primarily through communication experiences. Synthesizing the vast amount of research that has been published on communication and aging in numerous international outlets over the last three decades, the book's contributors include scholars from North America and the United Kingdom who are active researchers in the perspectives covered in their particular chapter. Many of the chapters work to deny earlier images of aging as involving normative decrement to provide a picture of aging as a process of development involving positive choices and providing new opportunities. A recuring theme in many chapters is that of the heterogeneity of the group of people who are variously categorized as older, aged, elderly, or over 65. The contributors review the literature analytically, in a way that reveals not only current theoretical and methodological approaches to communication and aging research but also sets the future agenda. This handbook will be of great interest to scholars and researchers in gerontology, developmental psychology, and communication, and, in this updated edition, will continue to play a key role in the study of communication and aging.
It can be argued that ATP is the most important molecule in cells. Not only is ATP the key energy source for cells, but it is also the source of phosphate groups that are transferred to a variety of substrate proteins via the action of elaborate families of protein kinases. An equally elaborate array of protein phosphatases can remove phosphate groups from proteins. It is now well established that protein phosphorylation is a widely used mechanism for cells to selectively modulate the function of a variety of proteins including enzymes, ion channels and pumps and structural proteins. In this volume of ACAG leading experts describe the evidence that protein phosphorylation is altered in aging and age-related disease. Protein phosphorylation controls fundamental processes such as transcription and translation, regulation of the cell cycle, signalling within and between cells, cell motility, synaptic function and so on. Recent findings are revealing how phosphorylation dependent signalling cascades may control lifespan with a prime example being the insulin-signalling pathway first described in c-elegans and now emerging as an important regulator of lifespan of mammals also. Many of the functional changes that occur during aging such as impaired learning and memory and altered energy metabolism are controlled by protein phosphorylation and it is, therefore, important to understand how mechanisms of protein phosphorylation may either mediate aging or provide adaptive responses that allow successful disease-free aging. The authors in addition to considering the roles of protein phosphorylation in aging describe the evidence that abnormalities in protein phosphorylation contribute to the pathogenesis of major age-related diseases including diabetes, atherosclerosis and neurodegenerative disorders such as Alzheimer's and Parkinson's diseases.
This text provides an interesting and informative account of the child's journey from the womb to the world outside, through childhood and into adolescence. It is based on the belief that it is vital for those training to work with children who have problems to understand what is typical or atypical in children's development.The first half of the book, discussing normal patterns of growth and development, is cross-referenced to equivalent chapters in the second half, which discuss the atypical route. These connections serve to emphasize the continuities between, and similarities of, children with typical and atypical conditions. Among the difficulties covered are: Pervasive developmental disorders Genetic disorders Physical impairments Learning difficulties Brain damage Emotional and behavioural disorders Personality disorders. Physical and mental illnessesThe text also deliberately links developmental and clinical psychology approaches in order to help readers connect their theoretical understanding of the physical and psychological problems of childhood with the practicalities of assessment, rehabilitation and treatment.
This book is an an up-to-date survey and summary of present knowledge and future expectations regarding the environmental causes of congenital malformations in human beings, beginning with the earliest discoveries of the 20th century up to the latest ideas and problems at its end, presents views and comments on the progress made over the century in understanding human prenatal maldevelopment.
The lipids of cellular membranes not only serve roles in controlling the structure and fluidity of the membrane, but are increasingly recognized for their roles as signalling molecules and modifiers of membrane protein function. Recent studies described in this volume reveal striking changes in membrane lipids during aging and in age-related diseases such as cancer, cardiovascular disease and neurodegenerative disorders. Lipids including inositol phospholipids, cholesterol, sphingolipids and ceramides play important roles in signalling cellular responses to stress and specific stimuli such as growth factors, cytokines and neurotransmitters. One or more of these lipid mediators has been linked to the pathogenesis of age-related diseases.
The second volume in this six volume set contains a balance of articles representing current theories and research across the domains of psychology, as they relate to aging. Ours is truly the age of aging. We are on the edge of a demographic, social, economic, and health transition revolution which will globally shape life in the Twenty-First Century. Increasingly, the aging of the population is having vast social and personal impact, changing past perceptions of the life-cycle; the organization of health care systems; social security policy; economics of retirement; political elections; cultural and religious views on aging and death; intergenerational relations; the nature of family life; the structure of communities and attitudes towards death.
People are living into old age. This is actually a revolutionary
statement as we look back to the start and then to the end of the
twentieth century. This demographic revolution raises important
practical and ethical issues and, for the most part, has led the
way for the field of gerontology, the study of aging, to emerge as
an area of increasing importance. With that in mind, Thorson has
revised and expanded his 1995 text to serve as an introduction to
the multidisciplinary field of gerontology.
There has been an increasing interest in the application of
dynamical systems to the study of development over the last decade.
The explosion of the dynamical systems framework in the physical
and biological sciences has opened the door to a new Zeitgeist for
studying development. This appeal to dynamical systems by
developmentalists is natural given the intuitive links between the
established fundamental problems of development and the conceptual
and operational scope of nonlinear dynamical systems. This promise
of a new approach and framework within which to study development
has led to some progress in recent years but also a growing
appreciation of the difficulty of both fully examining the new
metaphor and realizing its potential.
University Success Reading is designed for English language learners preparing for mainstream academic environments. A flexible three-part approach includes intensive and systematic skill development tied to learning outcomes along with authentic essays written by top professors from Stanford University. The Reading strand provides real-life learning experiences that prepare students to become fluent, automatic, and competent readers who can achieve academic autonomy. Highlights - Each part is a self-contained module allowing teachers to focus on the highest-value skills and content. Topics are aligned around science, technology, engineering, arts, and mathematics (STEAM) content. -- Parts 1 and 2 include challenging readings that allow students to engage with the content as they build essential reading and critical thinking skills. -- Part 3 provides a truly authentic experience with an extended essay that enables students to apply and expand the skills acquired in Parts 1 and 2. - Additional online readings, skill and vocabulary practices, collaboration activities, and assessments. - Strategies for academic success and soft skills delivered via online videos. - NEW! You can now create unique custom University Success content packs with Pearson Collections
In recent years, there has been extensive analysis of the health effects of menopause and the safety and efficacy of the various "treatments". There has also been rising concern about the appropriation and pathologization of menopause by medicine and its effects on women. At the same time, however, there has been relatively little reflection on the social, cultural, philosophical and ethical issues raised by both menopause itself and the way it has been handled by medicine. This text brings together a number of reflections from a broad range of areas including feminism, cultural studies, clinical medicine, sociology, philosophy and political science and includes the voices and experiences of menopausal women themselves. In an innovative series of essays, current thinking about medicine, society and the body is examined critically. Particular attention is given to the medical representations of menopause, biology and ageing, the history of medical approaches to women and the tensions between bio-medical models and other explanations of menopause. The issue of hormonal therapies is explored in the context of the connections between women, medicine, representation and cultural politic
In recent years, there has been extensive analysis of the health effects of menopause and the safety and efficacy of the various "treatments". There has also been rising concern about the appropriation and pathologization of menopause by medicine and its effects on women. At the same time, however, there has been relatively little reflection on the social, cultural, philosophical and ethical issues raised by both menopause itself and the way it has been handled by medicine. This text brings together a number of reflections from a broad range of areas including feminism, cultural studies, clinical medicine, sociology, philosophy and political science and includes the voices and experiences of menopausal women themselves. In an innovative series of essays, current thinking about medicine, society and the body is examined critically. Particular attention is given to the medical representations of menopause, biology and ageing, the history of medical approaches to women and the tensions between bio-medical models and other explanations of menopause. The issue of hormonal therapies is explored in the context of the connections between women, medicine, representation and cultural politic
University Success Reading is designed for English language learners preparing for mainstream academic environments. A flexible three-part approach includes intensive and systematic skill development tied to learning outcomes along with authentic essays written by top professors from Stanford University. The Reading strand provides real-life learning experiences that prepare students to become fluent, automatic, and competent readers who can achieve academic autonomy. Highlights - Each part is a self-contained module allowing teachers to focus on the highest-value skills and content. Topics are aligned around science, technology, engineering, arts, and mathematics (STEAM) content. -- Parts 1 and 2 include challenging readings that allow students to engage with the content as they build essential reading and critical thinking skills. -- Part 3 provides a truly authentic experience with an extended essay that enables students to apply and expand the skills acquired in Parts 1 and 2. - Additional online readings, skill and vocabulary practices, collaboration activities, and assessments. - Strategies for academic success and soft skills delivered via online videos. - NEW! You can now create unique custom University Success content packs with Pearson Collections
A symposium titled, "Touch in Infancy" was held to celebrate the
opening of the first Touch Research Institute in the world.
Although touch is the largest sense organ in the body, it is the
one that had been the most neglected and the only one to just
recently have a research institute. Designed to conduct basic
research on touch and on the skin, the institute will work with
wellness programs such as massage therapy and other kinds of touch
therapies to facilitate better health and to treat various
diseases. The institute's opening symposium featured presentations
from several of the world's leading experts in infant development.
Published in this volume, their work addresses the relevance of
touch to the neonate's well-being.
Based on the presentations given by well-known specialists at a
recent multidisciplinary conference of developmental
psychobiologists, obstetricians, and physiologists, this book is
the first exhaustive attempt to synthesize the present scientific
knowledge on fetal behavior. Utilizing a psychobiological analytic
approach, it provides the reader with an overview of the
perspectives, hypotheses, and experimental results from a group of
basic scientists and clinicians who conduct research to elucidate
the role of fetal behavior in development. Experimental and
clinical as well as human and animal data are explored via
comparative developmental analysis. The ontogeny of fetal
spontaneous activity -- via the maturation of "behavioral states"
-- and of fetal responsiveness to sensory stimulation is studied in
detail. Results are provided from studies of embryonic/fetal and
newborn behavior in chicks, rats, sheep, primates, and humans.
Knowledge of fetal behavior is crucial to the obstetrician,
neonatologist, developmental psychologist, and even the future
parents, in order to follow and assess the gradual development of
spontaneous responsive movements of the fetus. While assessing this
important information, this text also examines the neuro-behavioral
events taking place during the fetal period as an aid to
understanding normal and pathological life span development.
Recent research findings on the impact of nutrition on telomere length is unlocking the potential to combat premature aging at the cellular level. We have learned that while aging is a natural cellular process, premature aging is not and it can be positively impacted by an Evidence-Based Proactive Nutrition to Slow Cellular Aging diet plan. This book examines key elements of the biology of cell aging and focuses on enhancing mitochondrial function and preventing abnormal cell turnover thus preserving telomere length. It details the cellular damage caused by free radicals and ROS, explains the salutary effects of antioxidants, and the body's need for adequate nitrates and other nutrient substrates from which the body derives nitric oxide (NO) to support cardiovascular health. This book is the first to feature a simple do-it-yourself test of the effects of the diet on the availability of NO for - heart health. The book guides the reader through the rationale for a modified Mediterranean style diet that supplies the body with an adequate daily intake of essential nutrients, simple high antioxidants, and other functional foods. It includes simple, easy to prepare appealing recipes promoting a seamless transition to a healthy, age-defying lifestyle.
In this unique book emphasis is placed on tests necessary to
evaluate fetal well-being and to detect those fetuses at risk of
hypoxia and acidosis in utero. Written by pioneers in the neonatal
field, this publication contains chapters on the pathophysiology,
obstetric management, and collagen diseases of intrauterine growth
retardation. Ultrasound in detection of growth retarded fetuses is
explored, as well as magnetic resonance imaging and magnesium
substitution for the prevention of intrauterine growth retardation.
Containing never-before-published information, this volume is an
excellent reference source for both investigators in the field and
those entering it.
The first volume in this new series from The Center for the Study
of Child and Adolescent Development at The Pennsylvania State
University focuses on the relationship between the biological
stress circuits and the behavioral concomitants to stress in
animals and humans. The participants at this conference, a tribute
to Dean Evan G. Pattishall, Jr., discuss the developmental
implications of their work in relation to the periods of infancy,
childhood, and adolescence.
A symposium titled, "Touch in Infancy" was held to celebrate the opening of the first Touch Research Institute in the world. Although touch is the largest sense organ in the body, it is the one that had been the most neglected and the only one to just recently have a research institute. Designed to conduct basic research on touch and on the skin, the institute will work with wellness programs such as massage therapy and other kinds of touch therapies to facilitate better health and to treat various diseases. The institute's opening symposium featured presentations from several of the world's leading experts in infant development. Published in this volume, their work addresses the relevance of touch to the neonate's well-being.
'A stunner ... If you haven't got this book in your house, I don't know why' Chris Evans 'A startling wake-up call . . . Writing with the vim of a Bill Bryson and the technical knowledge of a scientist, Steele gives us a chance to grasp what's at stake' Independent 'An exhilarating journey . . . Steele is a superb guide' Telegraph 'A fascinating read with almost every page bursting with extraordinary facts . . . Read it now' Mail on Sunday Ageless is a guide to the biggest issue we all face. Ageing - not cancer, not heart disease - is the world's leading cause of death and suffering. What would the world be like if we could cure it? Living disease-free until the age of 100 is achievable within our lifetimes. In prose that is lucid and full of fascinating facts, Ageless introduces us to the cutting-edge research that is paving the way for this revolution. Computational biologist Andrew Steele explains what occurs biologically as we age, as well as practical ways we can slow down the process. He reveals how understanding the scientific implications of ageing could lead to the greatest discovery in the history of civilisation - one that has the potential to improve billions of lives, save trillions of dollars, and transform the human condition.
Rapid population aging, once associated with only a select group of modern industrialized nations, has now become a topic of increasing global concern. This volume reframes aging on a global scale by illustrating the multiple ways it is embedded within individual, social, and cultural life courses. It presents a broad range of ethnographic work, introducing a variety of conceptual and methodological approaches to studying life-course transitions in conjunction with broader sociocultural transformations. Through detailed accounts, in such diverse settings as nursing homes in Sri Lanka, a factory in Massachusetts, cemeteries in Japan and clinics in Mexico, the authors explore not simply our understandings of growing older, but the interweaving of individual maturity and intergenerational relationships, social and economic institutions, and intimate experiences of gender, identity, and the body.
One of the problems geriatricians are confronted with in everyday clinical practice is differentiating disease from the process of old age. The challenges of ageing require a better understanding of the essential biology of ageing in order to separate ageing from disease, and indeed ageing made worse by disease. Although the topic is large and diverse, this practical and easy-to-read reference book contains vital information on the biology of ageing. It provides a concise understanding of the changes that occur and focuses on the clinical implications of ageing. MCQs are featured throughout for revision and examination practice. The Biology of Ageing provides the reader with: . a learning guide on the biology of ageing through an overview of the changes that occur at both cellular and system levels . knowledge of how biological changes of ageing impact on physiology and the clinical relevance in medical practice . a practical consideration of these changes in disease presentations and how these changes may impact on disease management. This full-colour guide featuring slides, MRIs, figures and photographs is ideal for doctors training in geriatric medicine, practising geriatricians and those with an interest in management of older people.
Science is on the cusp of a revolutionary breakthrough. We now understand more about ageing - and how to prevent and reverse it - than ever before. In The Telomerase Revolution, Dr Michael Fossel, who has been at the cutting edge of ageing research for decades, describes how telomerase will soon be used as a powerful therapeutic tool, with the potential to intervene in age-related disease, dramatically extend life spans and even reverse human ageing. Telomerase-based treatments are already on offer, and have shown early promise, but much more potent treatments will become available over the next decade. This is the definitive work on the latest science of human ageing, covering both the theory and the clinical implications, taking readers to the forefront of one of the most remarkable advances in human medicine.
This book provides concrete scientific basis that we can conceive the possibility of modifying or even completely canceling aging process, despite the fact that aging is commonly regarded as the result of the overall effects of many uncontrollable degenerative phenomena. The authors illustrate in detail the mechanisms by which cells and the whole organism age. Actions by which it is possible, or will be possible within a limited time, to operate for modifying aging are also debated. The discussion is conducted within the frame and the concepts of evolutionary medicine, which is also indispensable for distinguishing between the manifestations of aging and: (i) diseases that worsen with age, and (ii) acceleration of normal aging rates, caused by unhealthy lifestyle habits and other avoidable factors. The book also discusses the impact of aging on overall mortality and the strange situation that, according to official statistics, aging does not exist as cause of death. This book is a turning point between a gerontology and geriatrics conceived as the study and vain treatment of an incurable condition and one in which these disciplines examine the how and why of a physiological phenomenon that can be modified up to a possible total control. This means transforming the medical prevention and treatment of physiological aging from the greatest failure to the greatest success of medicine.
In this paradigm-shifting book from acclaimed Harvard Medical School doctor and one of TIME magazine's 100 most influential people on earth, Dr. David Sinclair reveals that everything we think we know about ageing is wrong, and shares the surprising, scientifically-proven methods that can help readers live younger, longer. For decades, the medical community has looked to a variety of reasons for why we age, and the consensus is that no one dies of old age; they die of age-related diseases. That's because ageing is not a disease - it is inevitable. But what if everything you think you know about ageing is wrong? What if ageing is a disease? And that disease is curable. In LIFESPAN, Dr. David Sinclair, one of the world's foremost authorities on genetics and ageing, argues just that. He has dedicated his life's work to chasing more than a longer lifespan - he wants to enable people to live longer, healthier, and disease-free well into our hundreds. In this book, he reveals a bold new theory of ageing, one that pinpoints a root cause of ageing that lies in an ancient genetic survival circuit. This genetic trick - a circuit designed to halt reproduction in order to repair damage to the genome -has enabled earth's early microcosms to survive and evolve into more advanced organisms. But this same survival circuit is the reason we age: as genetic damage accumulates over our lifespans from UV rays, environmental toxins, and unhealthy diets, our genome is overwhelmed, causing gray hair, wrinkles, achy joints, heart issues, dementia, and, ultimately, death. But genes aren't our destiny; we have more control over them than we've been taught to believe. We can't change our DNA, but we can harness the power of the epigenome to realise the true potential of our genes. Drawing on his cutting-edge findings at the forefront of medical research, Dr. Sinclair will provide a scientifically-proven roadmap to reverse the genetic clock by activating our vitality genes, so we can live younger longer. Readers will discover how a few simple lifestyle changes - like intermittent fasting, avoiding too much animal protein, limiting sugar, avoiding x-rays, exercising with the right intensity, and even trying cold therapy - can activate our vitality genes. Dr. Sinclair ends the book with a look to the near future, exploring what the world might look like - and what will need to change - when we are all living well to 120 or more. Dr. Sinclair takes what we have long accepted as the limits of human potential and mortality and turns them into choices. THE EVOLUTION OF AGEING is destined to be the biggest book on genes, biology, and longevity of this decade. |
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