A growing body of medical research suggests that many medical tests used for diagnosis, prognosis, and monitoring response to treatment are unnecessary or inappropriate, yield inaccurate or misleading results, and add to the incidence of iatrogenic disease. Many such tests go into common clinical use without convincing documentation of their value because current methods for evaluating medical tests produce inconsistent results. Evaluating Medical Tests presents a systematic, objective methodology by which to determine the effectiveness of medical tests. Kraemer clearly and concisely shows how to define statistical terms and approaches consistently from study to study, how to stipulate statistical assumptions underlying various approaches, how to check for empirical validity, and how to judge the robustness of statistical outcomes, resulting in models that integrate many different approaches and extend the strengths of each. Statisticians, evaluators, researchers, practitioners, policymakers, and advanced students concerned with the evaluation of medical tests used to make clinical decisions for patient care and for research will find this essential, thought-provoking reading. "This volume is a pleasure to read. It succinctly combines carefully reasoned conceptualization with the mathematical methods for addressing test evaluation problems. With clinically relevant, illustrative examples, it draws on the author's extensive experience and research in biomedical statistics. It should be required reading for medical students and practitioners. It is invaluable to researchers and statisticians, and it provides a logical, scientific basis for efforts at medical cost containment. It is a classic! --from the Foreword by A. John Rush, M.D. "This fascinating book integrates a wide range of statistical and methodological concepts, reflects a thorough introduction to the issues confronted by evaluators of [medical] tests, and challenges motivated readers to adopt these procedures in their own research. This is an exciting book, with obvious strong policy implications concerning the way that [medical] tests are evaluated and the need for standards in this regard. . . . Evaluating Medical Tests should be of interest to all professionals who depend on tests as an adjunct in the decision-making process." --Paul R. Yarnold Northwestern University Medical School "Dr. Kraemer has undertaken a most massive and laudable task in writing Evaluating Medical Tests. . . . Dr. Kraemer's book stands as a flagship for those concerned to understand the reasons behind our escalating health care costs and the implications this holds for every American. . . . This leads us to one of the innovative features of Dr. Kraemer's book: 'This is not merely a statistical issue, or merely a medical issue, it is a national policy issue of the greatest importance.'. . . She does not assume that her readers are either statisticians or physicians. As such, she skillfully guides one through the terrain of medical and statistical jargon and points our where the assumptions of the statistics are either not stipulated or incongruent with the medical test and data being evaluated, thus rendering results and interpretations suspect. Another plus of Dr. Kraemer's writing is her willingness to use '. . . the first person singular to differentiate . . . comments from presentations of what I would consider provable or documentable facts. . . ' In so doing, she raised issues and calls medical professionals, policymakers, and patients into dialogue to consider the impact of the use of these various techniques in diagnosis. . . . Evaluating Medical Tests is of specific relevance to rehabilitation counselors who proceed with their clients through the maze of diagnostic and prognostic tests. . . . It is especially important for rehabilitation counselors who act as expert witnesses to have a working knowledge of this material to enhance their discussions with health care personnel." --Journal of Applied Rehabilitation Counseling

• Minimal Text. Specific details are available in the textbook. We will only provide text to set up and support the activities in the lab.
• Variety of Learning Activities. Within each lab exercise will be a variety of activities, including coloring and labeling anatomical figures, critical thinking and clinically-orientated questions that promote problem-solving.
• Effective Use of Illustrations. Simple line drawings, that allow important features to stand out, not just duplication of figures from the text book, will support the lab activities. Histology specific to each organ system is found in that system chapter, not all lumped together in a separate section.
• Active Diagrams. Many diagrams will be provided without labels, or in a coloring-book format to promote active learning of the material.

Desde su primera edicion, hace ya casi 40 anos, Koneman. Diagnostico microbiologico. Texto y atlas se ha convertido en la obra de referencia indiscutible para el diagnostico etiologico de las enfermedades infecciosas. Su contenido hace un abordaje completo de los fundamentos y de los procedimientos de laboratorio para la identificacion microbiologica aplicada a la bacteriologia, micologia y parasitologia, incluyendo los metodos tradicionales de aislamiento y los mas novedosos basados en reacciones inmunologicas y moleculares. Estudiantes, catedraticos investigadores y profesionales del diagnostico microbiologico y de las ciencias de la salud interesados en la identificacion y el estudio de las enfermedades infecciosas se beneficiaran con el contenido completo y de facil comprension de esta obra, asi como por la gran cantidad de ilustraciones. Esta 7.a edicion ha sido totalmente actualizada y mejorada con nuevos recursos pedagogicos, escenarios clinicos, fotografias, ilustraciones y recursos adicionales para estudiantes y docentes. Caracteristicas destacadas: Contenido revisado y actualizado Incluye un recuento completo de las tecnicas mas recientes de identificacion microbiologica basadas en tecnicas moleculares e inmunologicas Aplicaciones de microbiologia clinica y diagnostica en un solo volumen Principios de pruebas bioquimicas a detalle Inserto a color al final del libro con laminas que muestran distintos tipos de microorganismos Contenido exclusivo disponible en linea en thePoint : Para estudiantes : protocolos Para profesores : banco de imagenes, presentaciones en PowerPoint (R), generador de examenes y contenido disponible para sistemas de gestion de aprendizaje (LMS)

In recent decades, dendrimers - free-shaped synthetic macromolecules - have garnered a great deal of scientific interest because of their unique molecular nanostructure. Used in a variety of scientific applications, dendrimers are now widely regarded as a safer, more precise and more effective way to practice medicine. This book compiles and details cutting-edge research in science and medicine from the interdisciplinary team of the Michigan Nanotechnology Institute for Medicine and Biological Sciences, which is currently revolutionizing drug delivery techniques through the development of engineered nanodevices. Edited by Istvan J. Majoros and James R. Baker Jr, two prominent nanotechnology researchers, this book will appeal to anyone involved in nanotechnology, macromolecular science, cancer therapy or drug delivery research.

Now in its third edition, Introduction to Immunocytochemistry is an essential text for newcomers to the field, and will be a valuable reference for more experienced workers. Extensively expanded and updated, this volume covers both background theory and practical applications, including immunostaining methods using fluorescent, enzyme and gold labels.

With a strong emphasis on hands-on learning, this highly practical text helps you develop the phlebotomy-related knowledge and skills you need to become a confident, competent health care professional. The Fifth Edition accelerates learning by following key topics immediately with relevant exercises, integrating workbook elements and textbook content to deliver a complete learning experience. The text covers the latest professional standards and competencies while thoughtfully connecting them to the realities of practice today. Step-by-step guidelines for more than 20 collection procedures are provided, along with real-life scenarios and prompts emphasizing the phlebotomist's legal and ethical role in patient care decisions. Full-color photographs highlight important steps and relevant equipment, while illustrations depict anatomical components critical to proper technique. In addition, the digital edition includes videos and interactive exercises ideal for today's learners.

Ce jeu de douze planches plastifiees au format A4 est produit pour aider au diagnostic du paludisme humain par l'examen au microscope. Les planches sont concues dans un double but: apporter une aide pratique aux agents de sante dans leurs activites quotidiennes de diagnostic des infections paludiques et une aide pedagogique aux etudiants et stagiaires. Ce nouveau jeu a ete produit en tenant compte des observations et commentaires faits par un grand nombre de professionnels et d'experts qui ont utilise la deuxieme edition des Planches pour le diagnostic du paludisme (OMS, 2000).On y trouve des photographies au microscope qui montrent les differentes especes et morphologies du paludisme dans les frottis minces et epais. Elles fournissent des descriptions de P. falciparum, P. vivax, P. ovale et P. malariae, ainsi que des instructions detaillees sur la preparation et l'utilisation des solutions tampons et des solutions de coloration. Les photographies au microscope, toutes realisees au grossissement x 1000 et avec des colorants de Romanowsky, montrent nombre des variations possibles des parasites du paludisme. On y trouvera egalement des illustrations et des explications des erreurs courantes dans la preparation des frottis sanguins, de meme que des conseils pour la manipulation sans danger des echantillons de sang, afin d'eviter le plus possible toute exposition aux virus de l'hepatite et au VIH/sida. De nouvelles sections ont ete ajoutees sur les anticoagulants et le diagnostic des infections mixtes, ainsi que sur la reconnaissance d'autres parasites courants dans le sang peripherique. Les planches sont produites sous une forme plastifiee et etanche qui les rend solides et faciles a utiliser sur le terrain, comme sur la paillasse du laboratoire."

WHO and partners have been working towards devising an agenda, an action plan, tools and guidelines to increase access to appropriate medical devices. This document is part of a series of reference documents being developed for use at the country level. The series will include the following subject areas: * policy framework for health technology* medical device regulations* health technology assessment* health technology management* needs assessment of medical devices* medical device procurement* medical equipment donations* medical equipment inventory management* medical equipment maintenance* computerized maintenance management systems* medical device data* medical device nomenclature* medical devices by health-care setting* medical devices by clinical procedures* medical device innovation, research and development.These documents are intended for use by biomedical engineers, health managers, donors, nongovernmental organizations and academic institutions involved in health technology at the district, national, regional or global levels.Once established, the inventory serves as the foundation for moving forward within the HTM system and ensuring safe and effective medical equipment. The inventory may be used to develop budgets for capital purchases, maintenance and running costs; to build and support an effective clinical engineering department, by allowing for workshop planning, hiring and training of technical support staff, and establishing and maintaining service contracts; to support an effective medical equipment management program, such as planning preventive maintenance activities and tracking work orders; and to plan the stock of spare parts and consumables. The inventory may also be used to support equipment needs assessment within the health-care facility and to record the purchase, receipt, retirement and discarding of equipment. Facility risk analysis and mitigation, and emergency and disaster planning, are also supported by an inventory.

"Lab Literacy for Canadian Doctors" helps you to make better decisions about the right tests for typical clinical situations, quickly and efficiently, to improve patient care. Refer to this essential guide for: Advice and information on lab errors, false positives and negatives, and blood and tissue collection. A quick index summarizing the clinical utility of common tests. Sections on dermatology, ENT and respiratory system, endocrine system, fatigue, GI and hepatic system, gynecology and pregnancy, routine screening, and more.

Depuis sa premiere edition en 1983, il y a plus de vingt ans, le Manuel de securite biologique en laboratoire a donne des conseils pratiques sur les techniques de securite a appliquer dans les laboratoires a tous les niveaux. La bonne application des techniques microbiologiques et l'utilisation de l'equipement de securite biologique par du personnel bien entraine restent les piliers de la securite en laboratoire. Toutefois, la mondialisation, les progres technologiques, l'apparition de nouvelles maladies et les graves menaces liees a une utilisation ou a une mise en circulation deliberees de micro-organismes ou de toxines ont impose de revoir les procedures. Pour cette nouvelle edition, le manuel a donc ete considerablement revu et developpe.Le manuel couvre desormais aussi l'evaluation du risque et l'utilisation sans risque des techniques faisant appel a l'ADN recombinant. Il donne par ailleurs des lignes directrices pour la mise en service et la certification des laboratoires. Il presente les concepts de la securite biologique et les reglementations internationales les plus recentes sur le transport des matieres infectieuses. On y a egalement integre les informations sur la securite dans les laboratoires d'analyses medicales, publiees auparavant dans d'autres documents de l'OMS. Nous esperons que le manuel continuera d'inciter les pays a instituer des programmes de securite biologique et des codes nationaux de bonnes pratiques pour manipuler sans danger les matieres potentiellement infectieuses."