Supported by an extensive review of migraine pathogenesis and more than 200 case histories gleaned from the authors' personal experiences, this guide proposes two radical new concepts: all primary headaches are fundamentally a form of migraine and everyone may experience some manifestation of the migraine process in their life. Offering an in-depth overview of the migraine mechanism, including discussions of the neurogenic, vascular, platelet, and serotonin related components of the process, this source supplies extensive illustrations of the neuroanatomical structures involved in migraine and the latest insights from functional neuroimaging using BOLD fMRI and PET.

Following recent guidelines set by the International Classification of Headache Disorders, this reference presents the most current diagnostic and treatment protocols for migraine and other headache conditions. Chapters are authored by internationally renowned headache clinicians and scientists, including several past presidents of the American Headache Society and the International Headache Society. User-friendly and up-to-date, this reference offers useful tables, algorithms, and diagrams that lead clinicians to effective treatments for the management of migraine and the reduction of migraine severity.

Why, when and how does aggression go wrong? How can we make sense of apparently meaningless destructiveness and violence Aggression is a part of human nature that energises our relationships, acts as an impetus for psychic development, and enables us to master our world. More often, we focus on its more destructive aspects, such as the violence individuals inflict on themselves or others and overlook the positive functions of aggression. In Aggression and Destructiveness Celia Harding brings together contributions from experienced psychoanalysts and psychoanalytic psychotherapists to explore the roots of aggression and the clinical dilemmas it presents in psychotherapy. Beginning with accounts of aggression and destructiveness from a range of developmental and theoretical perspectives, the book provides useful insights into subjects including: Bullying and abusive relationships Male and female violence and destructiveness Depressive, perverse and psychotic states of mind Attacks on therapeutic treatment This book makes a valuable contribution to the attempt to make sense of human aggression, destructiveness and violence perpetrated against the self, others and reality. It will be of great interest to trainee and qualified psychodynamic counsellors, psychoanalytic psychotherapists and psychoanalysts.

Why, when and how does aggression go wrong? How can we make sense of apparently meaningless destructiveness and violence Aggression is a part of human nature that energises our relationships, acts as an impetus for psychic development, and enables us to master our world. More often, we focus on its more destructive aspects, such as the violence individuals inflict on themselves or others and overlook the positive functions of aggression. In Aggression and Destructiveness Celia Harding brings together contributions from experienced psychoanalysts and psychoanalytic psychotherapists to explore the roots of aggression and the clinical dilemmas it presents in psychotherapy. Beginning with accounts of aggression and destructiveness from a range of developmental and theoretical perspectives, the book provides useful insights into subjects including: Bullying and abusive relationships Male and female violence and destructiveness Depressive, perverse and psychotic states of mind Attacks on therapeutic treatment This book makes a valuable contribution to the attempt to make sense of human aggression, destructiveness and violence perpetrated against the self, others and reality. It will be of great interest to trainee and qualified psychodynamic counsellors, psychoanalytic psychotherapists and psychoanalysts.

Taking an all-inclusive look at the subject, Understanding Autism: From Basic Neuroscience to Treatment reviews state-of-the-art research on the diagnosis, treatment, and prevention of autism. The book addresses potential mechanisms that may underlie the development of autism and the neural systems that are likely to be affected by these molecular, genetic, and infectious etiologies. It reviews key findings that inform diagnosis, epidemiology, clinical neuroscience, and treatment. The book concludes with a discussion of the economic cost of autism and provides a biomedical and public health perspective of the impact of this devastating disease. With chapters authored by clinical and basic researchers at the forefront of molecular and systems neuroscience, clinical neuroscience, and health economics, the book presents a powerful and comprehensive synthesis of current research on autism and its underlying neural substrates. The book's two editors are considered elite pioneers in this area of research. Dr. Rubenstein was recently elected to the highly prestigious Institute of the Medicine, an honor reserved for those most committed to professional achievement and public service.

Brain Injury Treatment: Theories and Practices is a thorough and wide-ranging account of the rehabilitation of brain injury.

Written from an international perspective, this book presents a detailed discussion of the basic science of brain injury. It explains the treatments used in brain injury rehabilitation and covers new methods of rehabilitation, including complementary medicine theories. It contains a wealth of information on different neurosurgical and neuropsychological treatments. It also includes a comprehensive reference to the theories underlying rehabilitation practices and chapters on community reentry and family dynamics following brain injury.

It will be an invaluable tool to students from psychology, medicine, physical and occupational therapy studying the treatment and aftercare of people with brain injury.

Originally published in 1993, the previous decade had seen considerable development in the field of neuropsychological rehabilitation following brain damage, and the use of computerized methods attracted attention and stimulated controversy. This practically-oriented text reviews representative examples from the literature at the time relating to the training of cognitive systems with the emphasis on studies describing the use of computerized methods. The topic is discussed in context and the contents include sections on cognitive change in neurological disorders, assessment techniques, the interaction between cognition and behaviour and the advantages and disadvantages of the use of microcomputers. The authors describe the evaluation of a computerized cognitive retraining programme run at the Regional Neurological Centre in Newcastle-upon-Tyne and draw on their experience of running such programmes to give practical guidance to those wishing to set up cognitive retraining programmes.

New Developments in Dementia Prevention Research addresses a dearth of knowledge about dementia prevention and shows the importance of considering the broader social impact of certain risk factors, including the role we each play in our own cognitive health throughout the lifespan. The book draws on primary and secondary research in order to investigate the relationship between modifiable factors, including vascular and psychosocial risks, that may affect the incidence of dementia. Bringing together world-leading expertise from applied science, medicine, psychology, health promotion, epidemiology, health economics, social policy and primary care, the book compares and contrasts scientific and service developments across a range of settings. Each chapter presents these themes in a way that will ensure best practice and further research in the field of dementia prevention is disseminated successfully throughout the world. Perhaps most importantly, chapters also question what type of social responsibility we are prepared to embrace in order to address the challenges inherent in dementia prevalence. New Developments in Dementia Prevention Research includes contributions from leading authorities in brain health and dementia prevention and provides an essential contribution to the discourse on dementia prevention. It will be of great interest to academics, researchers and postgraduate students engaged in the study of the psychological and social aspects of aging and dementia.

Unrepressed Unconscious, Implicit Memory, and Clinical Work analyses the psychological and neurobiological characteristics of what nowadays goes under the name of "unrepressed unconscious", as opposed to Freud's earlier version of a kind of "repressed unconscious" encountered and described initially in his work with hysterical patients. Pioneering Italian psychoanalyst and neuroscientist Mauro Mancia has distinguished this seminal Freudian concept from an earlier version of the unconscious (preverbal and pre-symbolic) that he terms "unrepressed", and which he describes as "having its foundations in the sensory experiences the infant has with his mother (including hearing her voice, which recalls prosodic experiences in the womb). In connection with this description of two different kinds of unconscious, a 'double' system of memory has been identified: if a traumatic event or series of events takes place when the nervous system is not ready to encode them linguistically and register them within the declarative memory system, they leave a trace within the implicit memory and particularly within the right brain, which both Mancia and Schore see as the seat of implicit memory.

Duchenne Muscular Dystrophy (DMD) is one of the most prevalent genetic disorders of childhood and currently stands as an incurable condition. This authoritative guide provides a clear overview of the latest current and experimental approaches to the treatment of DMD and examines the clinical, genetic, and pathophysiological aspects of the disease in the context of emerging therapeutic modalities. The only available source on the subject, this reference emphasizes the importance of accurate diagnosis, carrier detection, and genetic counseling, and supplies state-of-the-art contributions on pharmacological interventions, regenerative medicine, and gene therapy.

Filling a gap that exists in most traumatology literature, The Posttraumatic Self provides an optimistic analysis of the aftermath of a traumatic event.

This work appreciates the potentially positive effects of trauma and links those effects to the discovery of one's identity, character, and purpose. Wilson and his distinguished contributors explore the nature and dynamics of the posttraumatic self, emphasising human resilience and prompting continued optimal functioning. While taking into consideration pathological consquences such as posttraumatic stress disorder (PTSD), the authors study the impacts a traumatic event can have on one's inner self, and they help the victims transform such an event into healthy self-transcendent lifecycles. The Posttraumatic Self will help victims and healers transform the way they deal with the complexities of trauma by making important connections that will allow for healing and growth.

Mitochondria produce the chemical energy necessary for eukaryotic cell functions; hence mitochondria are an essential component of health, playing roles in both disease and aging. More than 80 human diseases and syndromes are associated with mitochondrial dysfunction; this book focuses upon diseases linked to these ubiquitous organelles. Accumulation of mitochondrial DNA damage results in mitochondrial dysfunction through two main pathways. Mutation in mitochondrial DNA causes diseases such as Kearns-Sayre syndrome and Pearson syndrome. Mutation in chromosomal DNA causes diseases such as Parkinson's disease and schizophrenia. These and many other diseases are reviewed in this book. Key Features Presents the detailed structure of mitochondria, mitochondrial function, roles of oxidants and antioxidants in mitochondrial dysfunction. Includes summary of both causes and effects of these diseases. Discusses current and potential future therapies for mitochondrial dysfunction diseases Explores a wide variety of diseases caused by dysfunctional mitochondria.

"The Posttraumatic Self "will be organized into three sections, the first of which will focus on the effects that trauma can have on the stages of attachment early in life, and the continuing psychological mechanisms that can perpetuate later life-span development. The second section will present a new integrative psychobiological model of trauma therapy aimed at furthering the understanding of the transformative processes brought about by traumatic events and the subsequent stress that follows. The final section of the book will address a variety of issues concerning the restoration of meaning and the re-integration of personality following a traumatic experience. Wilson, Kalsched, and their assembled group of contributors are pre-empting an approaching paradigm shift in our current understanding of the interconnectedness of trauma, PTSD, human development, resiliency and the integrative processes of the self. With the emergence of various integrative approaches to the study of trauma and PTSD, this book has the potential to be a frontrunner in the attempts to combine our understanding of the "inner and outer worlds" of trauma.

Filling a noticeable gap in the market for a new text solely focused on Dementia with Lewy Bodies, this book discusses cutting-edge topics covering the condition from diagnosis to management, as well as what is known about the neurobiological changes involved. disorder's recognition as a common cause of cognitive impairment, its clinical features, its underlying neurobiology, investigative changes, and management, this is undoubtedly a much-needed work in what is an important and rapidly progressing field. modern text is equally accessible to clinicians such as old-age psychiatrists, geriatricians and neurologists, as well as allied health professionals with a particular interest in the area.

Drawing on the pioneering work of Janet, Freud, Sullivan, and Fairbairn and making extensive use of recent literature, Elizabeth Howell develops a comprehensive model of the dissociative mind. Dissociation, for her, suffuses everyday life; it is a relationally structured survival strategy that arises out of the mind's need to allow interaction with frightening but still urgently needed others. For therapists dissociated self-states are among the everyday fare of clinical work and gain expression in dreams, projective identifications, and enactments. Pathological dissociation, on the other hand, results when the psyche is overwhelmed by trauma and signals the collapse of relationality and an addictive clinging to dissociative solutions. Howell examines the relationship of segregated models of attachment, disorganized attachment, mentalization, and defensive exclusion to dissociative processes in general and to particular kinds of dissociative solutions. Enactments are reframed as unconscious procedural ways of being with others that often result in segregated systems of attachment. Clinical phenomena associated with splitting are assigned to a model of "attachment-based dissociation" in which alternating dissociated self-states develop along an axis of relational trauma. Later chapters of the book examine dissociation in relation to pathological narcissism; the creation and reproduction of gender; and psychopathy. Elegant in conception, thoughtful in tone, broad and deep in clinical applications, Howell takes the reader from neurophysiology to attachment theory to the clinical remediation of trauma states to the reality of evil. It provides a masterful overview of a literature that extends forward to the writings of Bromberg, Stern, Ryle, and others. The capstone of contemporary understandings of dissociation in relation to development and psychopathology, The Dissociative Mind will be an adventure and an education for its many clinical readers.

The vegetative state - a condition in which someone is awake but unaware with no evidence of a working mind - is both emotive and challenging. This condition and that of someone who gains partial recovery of mental and neurological functions - known as the minimally conscious state - have provoked intense debate and considerable interest amongst scientists, health care professionals, ethicists, philosophers and lawyers. This unique special issue unites many experts in the field to review and discuss the many advances made in our understanding of these conditions. The strength of this special issue lies in the wide range of topics discussed - from definitions and diagnostic criteria to hotly debated topics such as whether a person in the vegetative state is truly unaware. This edition will serve as both a useful reference to those caring for people in these conditions as well as to those investigating the physiological basis of human consciousness.

Over the past sixteen years, since its initial introduction to professional circles, Eye Movement Desensitization and Reprocessing (EMDR) has become increasingly popular among practitioners dealing with trauma. While a number of empirical studies, clinical experience, and published scholarly work have confirmed the efficacy of this therapeutic method in the treatment of trauma and PTSD, there remains a large gap in the literature pertaining to this burgeoning area. Most of the existing literature on EMDR concentrates on the theoretical constructs of the method and/or the physical methodology of the treatment. The proposed book will explore an area that has, until now, been left unconsidered. EMDR From the Heart examines the nature of the therapeutic relationship as it pertains to EMDR use in psychotherapy. Mark Dworkin has been in practice as a psychotherapist for over 30 years - specializing in the treatment of PTSD for the last 25 of those years ...

The European Dementia Consensus Network (EDCON) was formed by opinion leaders from the fields of old-age psychiatry and neurology in order to evaluate and improve the clinical management of patients with dementia across the continent.

Summarizing the work of EDCON 's working group on standards in dementia care, this text compares and contrasts the differences in clinical practice and the provision of services throughout Europe, and also examines the various roles involved in multi-disciplinary care of patients with dementia.

"Exposure Treatment for Anxiety Disorder"s is a unique volume, as it draws together the latest research on the rapidly-expanding field of anxiety disorders and illuminates how to correctly apply the proven methodology of behavioral therapy techniques to the variety of situations that face today's mental health professional. That said, cognitive therapy has in the last 10 years gotten increased attention as an alternative to behavior therapy in the treatment of anxiety disorders. But while it is gaining acceptance among practitioners, cognitive therapy has yet to illustrate substantial benefits above those that behavior therapy can already provide. In light of the aforementioned, coupled with the pressure many practitioners feel from managed care paradigms and shrinking healthcare coverage, this book will be a welcome resource allowing for increased clarity of action, accountability, and ultimately, positive client outcome. Each chapter is designed to address pivotal aspects in the assessment, formulation and diagnosis, and treatment of anxiety disorders, to a sufficient depth that the generalist practitioner will be comfortable using this book as a guide when working with the anxiety disordered client.

"Exposure Treatments for Anxiety Disorders is a unique volume, as it draws together the latest research on the rapidly-expanding field of anxiety disorders and illuminates how to correctly apply the proven methodology of behavioral therapy techniques to the variety of situations that face today's mental health professional. That said, cognitive therapy has in the last 10 years gotten increased attention as an alternative to behavior therapy in the treatment of anxiety disorders. But while it is gaining acceptance among practitioners, cognitive therapy has yet to illustrate substantial benefits above those that behavior therapy can already provide. In light of the aforementioned, coupled with the pressure many practitioners feel from managed care paradigms and shrinking healthcare coverage, this book will be a welcome resource allowing for increased clarity of action, accountability, and ultimately, positive client outcome. Each chapter is designed to address pivotal aspects in the assessment, formulation and diagnosis, and treatment of anxiety disorders, to a sufficient depth that the generalist practitioner will be comfortable using this book as a guide when working with the anxiety disordered client.

This reference analyzes the cellular and molecular biology and mechanisms of the blood-brain barrier (BBB) and presents the most recent studies on the role of the BBB in the development and initiation of a wide range of physiological and pathological conditions affecting the central nervous system.

This book addresses an important and relatively neglected topic in the scientific literature: individuals with autism spectrum disorder (ASD) who have dealings with the legal system. It examines issues and implications for autistic people, who have a significant risk for engagement with the legal system in some capacity (e.g., witness/bystander, victim, or perpetrator). Key areas of coverage include: Autistic people as victims and perpetrators of criminal activities, including violence, stalking, sexual exploitation, and cybercrime. Risks for unlawful behavior in individuals with autism and Asperger's. Legal assessment issues, such as witness protection and postconviction diagnoses. Legal outcomes for autistic people, including case law, prevention, service provisions in correctional settings, and rights and support systems. The Handbook of Autism Spectrum Disorder and the Law is an essential, comprehensive resource that explores the risk for unlawful behaviors affecting autistitc people as victims and perpetrators, as well as related issues of assessment and treatment, and outcome. It is a must-have reference for researchers, clinicians/practitioners, and graduate students in psychology, psychiatry, social work, and law, as well as professionals in such related fields, as criminology/criminal justice and the legal system.

Providing a thorough overview of rapid developments in medical therapy, surgery, and angioplasty, this reference provides a complete review of carotid artery stenosis treatment, as well as a clear overview of carotid surgery and stenting. Offering chapters by seasoned authorities on epidemiology, imaging with ultrasound and angiography, cholesterol lowering, blood pressure management, homocysteine treatment, and diet modification, this guide is a stand-alone source for current information and understanding of this burgeoning science.

The Living Well with Dementia Course: A Workbook for Facilitators will be an indispensable guide to providing support to people after they have received a dementia diagnosis. The workbook provides facilitators with a realistic but positive approach to helping people with dementia understand and adjust to their condition, helping them to live as well as possible. This workbook outlines the Living Well with Dementia course, a post-diagnostic course for people who have recently received a diagnosis of dementia. Its session-by-session structure, along with e-resources including handouts for course participants, will help facilitators provide a realistic but positive approach to support after a diagnosis. Aimed at facilitators, and drawing on the authors' many years of clinical and research experience, The Living Well with Dementia Course workbook will be of great assistance to healthcare professionals and support workers in many different settings, including specialist NHS dementia services, primary care services and the voluntary and community sector.