Affecting an estimated 2.5 million people worldwide, multiple sclerosis (MS) is the most common neurological cause of debilitation in young adults. Incurable, and with the precise causes still unknown, both diagnosis and management of the condition is complicated. This book summarizes the latest understanding of the causes of the disease, using accessible, bullet-point text to describe key clinical features and diagnostic criteria. Disease-modifying therapies and management of symptoms, including fatigue, tremor and cognitive changes, are covered in detail. With a chapter focusing solely on presentations in the emergency room, the importance of recognizing these neurological emergencies is emphasised, along with indications for admission in MS patients. The impact of MS on women's reproductive health and the increasing recognition of MS in pediatric patients is also explored. An up-to-date and practical approach to the accurate diagnosis and management of MS, this is an invaluable resource for both hospital and outpatient settings.

Therapists play a crucial role in helping children and their families as they navigate the often stormy course of living with autism spectrum disorders (ASD). As cases of autism are increasingly diagnosed, the number of therapists with specialized training cannot keep pace. What is the clinician without prior experience with this disability to do when considering working with a child on the autism spectrum? This start here book a practical beginner s guide to ASD for therapists provides the answer. Without getting bogged down in the complexity of the disorder or attempting to turn practitioners into autism specialists, it points therapists novices and seasoned alike in the right direction so they re better equipped to provide support. Because autism can manifest in so many different ways, no cookie-cutter treatment exists and therapists need to be conversant with the basics, from assessment and treatment approaches to common therapeutic issues that can arise. This book serves as an invaluable road map.

Viewing ASD as a social communicative disorder, the authors provide a sound background of its manifestations and therapeutic interventions, helping therapists to define treatment issues and prepare for potentially difficult client encounters. Filled with practical insights and guidance, the book explains how to ask the right questions of parents and how to assess their answers. It presents a philosophy to guide parents and others in changing their perceptions of the child s disability so as to pave the way for effective approaches to be used within the child s environment. Concrete tools are provided to help determine goodness of fit between the therapist and client, in addition to several helpful reproducible intake and assessment forms available for download on an accompanying CD. Charting the Course is an important therapist s guide representing an all-encompassing approach to working not only with children and their parents, but also with their siblings, family members, and those in the community who are involved in their lives. Ultimately, this book provides a reassuring anchor for any clinician new to treating this disability as well as for those who are seeking alternative approaches to their ongoing work with children diagnosed with ASD."

The series CNS Neurotransmitters and Neuromodulators is destined to be the definitive reference work on the physiology and pharmacology of the central nervous system. Written by an outstanding group of international authors, chapters cover a wide range of interdisciplinary aspects of the subject.
This first volume includes an in-depth examination of acetylcholine, ranging from the localization of synthetic enzymes through electrophysiology, pharmacology, and molecular biology to behavioral importance in learning and memory. This indispensable and comprehensive reference keeps you abreast of new developments in several areas of neuroscience.

Written by a multi-disciplinary group of leading practitioners, Sexual Offending Against Children provides an account of the practice, policy and management issues involved in the assessment and treatment of adult and adolescent sexual offenders against children. Written for practitioners from all disciplines concerned with this area of work, it is underpinned by a strong theoretical base, giving a practical and detailed description of the management of sexual offenders, as well as the potential impact on service providers.

Mainstream analysts working in the Jungian tradition have largely neglected adolescents. Mara Sidoli and Gustav Bovensiepen remedy that omission by showing how and why psychological and physical abuse suffered by young children erupts in violent and destructive behavior against the self and others. Using clinical material, they establish the link between archetypal imagery, disturbed behavior, and instinctual drive.

Drawing from all schools of analytical psychology, the authors, along with several associates, focus mainly on severe neurotic disturbances and behavioral problems occurring in adolescence. Because most disturbances originate in the body, the contributors concentrate on self-destructive behavior: suicide, self-mutilation, and other self-damaging acts. Focused heavily on the treatment of these adolescents, the text has selections from an international group of contributors, providing diverse accounts of both theoretical and technical approaches to therapy. The case histories illustrate the relationship between the analyst and the adolescent patient as it develops in consultation. Interweaving the concepts of Jung, Freud, and others makes this volume a unique contribution to contemporary psychoanalysis. It will be of sustained interest to psychoanalysts, child psychotherapists, social workers, psychiatrists, and psychologists.

The diagnosis and treatment of memory disorders pose considerable problems for the clinician. Many different organic conditions produce disturbances of memory, but the relationship between cerebral pathology and memory disturbance can often be difficult to establish. Furthermore, assessment and treatment require specialized skills and merit an inter?disciplinary approach towards patient management. Despite the many books which have been written on various aspects of memory disorders, none so far has been specially designed to give practical help to those who have to deal with diagnosis and subsequent management of patients with memory disturbance resulting from specific types of cerebral pathology. The author achieves this aim by organizing his book on the basis of clinical aetiology. Anatomical and psychological perspectives are also introduced, but the emphasis is on approaches which will help clinicians in the management of patients with specific neurological diseases. For example, the essential topic of differential diagnosis is given prominence throughout: the principles of diagnostic assessment are discussed in a separate chapter, and specific diagnostic features are also outlined in each of the chapters dealing with individual cerebral pathologies. For the discussion of assessment, the author draws on his own extensive experience as a practising clinical neuropsychologist to describe and evaluate the range of existing memory test procedures, and to suggest additional procedures as appropriate. Where evidence exists on the treatment of memory disorders in specific neurological conditions, this is also discussed and critically reviewed. Full references are also given for thosewishing to develop their own assessment of therapeutic procedures. The text is extensively illustrated, with much previously unpublished material on individual neurological conditions giving some remarkable insights into the links between cerebral pathology and memory dysfunction. Mainly intended for practising neurologists and clinical neuropsychologists, anyone whose work brings them into contact with patients suffering from memory disturbance will find this book invaluable.

After progressive multiple sclerosis landed Dr Wahls in a tilt/recline wheelchair, she exhaustively researched autoimmune disease and brain biology, and embraced the concepts of functional medicine. Determined to overcome her initial dismal diagnosis,, she made a choice to rely on food as her medicine and begun using paleo concepts as guidelines for her unique, nutrient rich plan. As her broken biochemistry began to fix itself, Dr Wahls soon retained full mobility and left her wheel chair behind for good. Dr Wahls transformation was nothing short of miraculous, and she knew these treatments could be life-changing for anyone struggling with an autoimmune condition. Now, Dr Wahls shares her pioneering research along with three levels of nutrient-rich diets that can help you reverse the debilitating symptoms of your disease. The Wahls Protocol gave Dr Wahls her life back. Give it the chance to restore yours.

"This outstanding resource offers comprehensive presentations of the latest basic knowledge and the most advanced research on neuropeptides of the respiratory tract covering the structure, receptors, molecular biology, and function of each important neuropeptide and examining how they relate to disease. Demonstrates the utility of immunohistochemistry, autoradiography, molecular biology, smooth muscle contraction, and glandular secretion for the study of neural function both in vitro and in vivo "

This book provides a state-of-the-art review of high-level vision and the brain. Topics covered include object representation and recognition, category-specific visual knowledge, perceptual processes in reading, top-down processes in vision -- including attention and mental imagery -- and the relations between vision and conscious awareness. Each chapter includes a tutorial overview emphasizing the current state of knowledge and outstanding theoretical issues in the authors' area of research, along with a more in-depth report of an illustrative research project in the same area.
The editors and contributors to this volume are among the most respected figures in the field of neuropsychology and perception, making the work presented here a standard-setting text and reference in that area.

"Sexual Difference: Masculinity and Psychoanalysis" offers a critical exploration of issues of gender in psychoanalysis. It acknowledges and unpacks the complexity of theory and writing in this area, particularly the way sexual difference can only be thought about from a gendered position. As the book is written by a male academic and psychologist, its orientation is towards the way masculinity is expressed in theory and practice, and how this influences the experience and construction of both masculinity and femininity in contemporary culture. In addition, Stephen Frosh describes how psychoanalysis itself can be seen as a system and approach heavily imbued with gender assumptions, and how the form and content of its theories express many of the dilemmas of sexual difference which it seeks to overcome. The text is written in an accessible and self-reflexive style. It introduces major strands of psychoanalytic theory on sexual difference, particularly those associated with the Kleinian and Lacanian traditions, and includes a detailed exploration of the gender assumptions apparent in some of Freud's work.

Chemical Dependency and Antisocial Personality Disorder gives you the information and clinical skills necessary to assess and evaluate persons suffering from substance abuse and/or antisocial personality disorders and details how you can develop effective psychotherapy and treatment strategies. From its helpful pages that contain diagnostic criteria and clinical interviewing and assessment guidelines, you learn to accurately diagnose substance use and antisocial personality disorders. The book also provides you with the historical and clinical perspectives of such disorders and their epidemiology and etiology to give you a thorough background and understanding of the subject. Case studies and therapy vignettes are included to provide you with actual clinical examples to illustrate concepts and ideas. You will appreciate the book's in-depth discussions of treatment strategies that can greatly enhance your effectiveness. You'll find this volume is an invaluable research resource for refreshing your approaches for helping persons with substance abuse and antisocial personality disorders.Much of the content of Chemical Dependency and Antisocial Personality Disorder is based on the author's two decades of experience working with patients suffering from substance use and antisocial personality disorders. Some topics addressed include: accurate differential diagnosis resistance the use of structure in treatment therapist-patient relationship dynamics treatment outcome effectiveness, relapse, and recovery. Alcohol/drug counselors, psychiatrists, psychologists, and corrections, probation, and parole officers who want to be more effective in their work with chemically dependent and antisocial clients will find this a practical, helpful, and informative guide. This enlightening book examines many of the most difficult and clinically problematic issues that are associated with the psychotherapy and rehabilitation of chemically dependent and/or antisocial patients. Much of the content of Chemical Dependency and Antisocial Personality Disorder is based on the author's two decades of experience working with patients suffering from substance use and antisocial personality disorders. Some topics addressed include accurate differential diagnosis, resistance, the use of structure in treatment, therapist-patient relationship dynamics, and treatment outcome effectiveness, relapse, and recovery. Alcohol/drug counselors, psychiatrists, psychologists, and corrections, probation, and parole officers who want to be more effective in their work with chemically dependent and antisocial clients will find this a practical, helpful, and informative guide.

Certain characteristics of autism, such as difficulty understanding social cues, may make women vulnerable to potentially dangerous situations. Robyn Steward has written this supportive guide to help all women on the autistic spectrum live independently, make their own choices in life, and be safe whilst doing so. This book will provide you with the knowledge to recognise potential risks to your personal safety and the skills and strategies required to avoid and overcome them. Informed by a survey of, and interviews with, women on and off the autistic spectrum, it explores common safety issues encountered by women and offers practical advice to help you stay safe and supported in your independence. Topics covered include friendships, relationships and sex, alcohol and drugs, money and employment and staying safe outside the home and online. This handbook is your guide to super safe living as an independent woman and will help you to stay safe whilst living life to the full. It may also be of interest to your family, friends and carers, giving them insight into life on the spectrum and confidence that you will enjoy your independence in an informed and safe manner.

Since the publication of the original edition in 1982, pesticide-related poisonings, both single cases and epidemic-scale situations, have continued to occur unabated. This new edition of Pesticides and Neurological Diseases reviews current literature describing the effects of insecticides (chlorinated hydrocarbons, organophosphorus and carbamate esters, and the pyrethroid esters), fungicides (organomercurials, dithiocarbamates), and herbicides (chlorophenoxy acids and esters) on the mammalian nervous system. Acute and chronic exposures have resulted in both subtle and serious neurological deficits in the peripheral and central nervous systems, marked by transient effects preceding those of delayed onset and of persistent duration. The chapters have been largely revised and rewritten to introduce newer theories of mechanism(s) of action studied at the laboratory bench. New findings and observations on human intoxications are included as well.
This reference will interest physicians involved in environmental medicine and occupational health, as well as graduate students and researchers in the fields of neurophysiology, pharmacology, and the toxicology of pesticides. It may also be useful to the layperson interested in learning more about chemicals routinely used in the home, garden, greenhouse, orchards, and fields.

This volume is a first of its kind, addressed principally to the professional reader. While it is not intended to be exhaustive, its aim is to sketch a broad picture of some of the nondrug and nonsurgical treatment strategies with a demonstrated basis in conventional scientific method. Likewise, though it does not include all those who have contributed to the emergence of this exciting new field, it assembles those authors whose seminal work has earned them international reputations.
This volume's declared purpose is to provide a state-of-the-art guide to methods and techniques in the behavioral treatment of epilepsy and to their basis in theory. The editors hope that it will catalyze the evolution of their acceptance as standard elements, where appropriate, in the clinical activities of independent practitioners, clinics, and agencies that service those with convulsive disorders.

This important book equips mental health professionals with sound and practical strategies for responding effectively to disruptive or violent patients. The authors identify the warning signals of potential violence and offer detailed guidelines on assessment; verbal, pharmacological, and physical intervention; use of seclusion and restraints; and management of hostage situations. Of particular value is the emphasis on ways of preventing a potentially dangerous person from erupting into physical violence. Full consideration is also given to institutional responses to violent incidents.

This volume integrates past clinical findings with the latest research on cerebral asymmetry in order to identify why humans process information in different ways. A must for anyone who wants to understand human cognitive nature further, specifically the reasons why we are "wired" a certain way and whether these cortical circuits are flexible enough to be altered, this book presents the most up-to-date information on hemispheric differences within normal and clinical populations. Its focus on sex, handedness, and developmental differences is critical to the derivation of a better perspective on how future research should be conducted in this expanding science.
Iaccino begins by explaining basic brain structures and types of cognitive styles assigned to each hemisphere. He then details studies involving various clinical populations -- psychophysiological, split-brain, dyslexic, and psychotic -- to support the claim that the two hemispheres are different, morphologically and functionally speaking. Applying this clinical research to the more normal population, the author uncovers striking cortical variations between the sexes and between the handedness groups, along with developmental changes which occur as a function of time. Finally, he provides a detailed summary of the previous chapters and highlights where asymmetrical research may be headed in the future.

Deep brain stimulation (DBS) is a widely used therapy for movement disorders such as Parkinson's disease, essential tremor, and dystonia. Its therapeutic success has led to the application of DBS for an increasing spectrum of conditions. However, the fundamental relationships between neural activation, neurochemical transmission, and clinical outcomes during DBS are not well understood. Drawing on the clinical and research expertise of the Mayo Clinic Neural Engineering Laboratories, this book addresses the history of therapeutic electrical stimulation of the brain, its current application and outcomes, and theories about its underlying mechanisms. It reviews research on measures of local stimulation-evoked neurochemical release, imaging research on stimulation-induced neural circuitry activation, and the state of the art on closed-loop feedback devices for stimulation delivery.

The most misunderstood and complex subject in medicine is the hyperpathic pain of sympathetic dystrophy. More common than previously thought, it comprises between 10 and 20 percent of chronic pain patients. Understanding this self-perpetuating pain -- which "never stops" -- requires unbiased knowledge of physiology and pathology.
Chronic Pain: Reflex Sympathetic Dystrophy, Prevention, and Management is devoted to the subject of Reflex Sympathetic Dystrophy (RSD). The book classifies the different stages of RSD and describes the qualitative and quantitative differences between natural endorphins and synthetic narcotics. Included are long-term follow-ups on sympathectomy patients.
This important reference explains why sympathectomy fails, but nerve block and physiotherapy is successful in the treatment of RSD. In addition, the mechanism of development of RSD is clarified through an extensive collection of drawings and anatomical pictures as well. Other topics include thermographic methods for the diagnosis of RSD, the role of ACTH in the management of chronic pain, and comparisons between the effects of ACTH and those of corticosteroids.

Features
o Classifies the different stages of RSD
o Features the most comprehensive coverage of the literature on RSD and its related aspects
o Describes qualitative and quantitative differences between natural endorphins and systemic narcotics
o Examines the role of ACTH in the management of chronic pain
o Clarifies the mechanism of development of RSD through an extensive collection of drawings and anatomical pictures
o Explains why sympathectomy fails, but nerve block and physiotherapy is successful in the treatment of RSD

Recent advances in medicine for resuscitation and care have led to an increased number of patients that survive severe brain damage but who are poorly responsive and non-communicative at the bedside. This has led to a striking need to better characterize, understand, and manage this population who present a real challenge for the assessment of pain and for planning treatment. This edited collection provides clinicians with a guide to recent developments in research on pain perception and assessment, and the detection of consciousness and communication in patients with disorders of consciousness (DOC). With contributions from leading global researchers, the book gives an overview of issues concerning the assessment of pain. It also covers the development of suitable tools both to improve pain management and to detect consciousness and communication in these patients, to influence their prognosis and treatment, and their quality of life. Methodological and ethical issues concerning the implication for future research are also considered. The book will be an invaluable guide for clinicians, medics and therapists working in rehabilitation and acute care, particularly in the demanding field of pain perception, pain assessment and detection of consciousness and communication in patients with DOC. It will also be useful for students and researchers in neuropsychology and medical sciences.

The book proposes that a preparation of antioxidants and micronutrients, in combination with standard therapy, may reduce progression and improve management better than standard therapy alone for Alzheimer's, Parkinson's, and Huntington's disease, as well as PTSD, traumatic brain injury, concussions, and cerebral vascular insufficiency. The book presents the latest research on the effects of micronutrients and recommends formulations for use in combination with standard therapies for these neurodegenerative diseases and conditions.

Developmental Disorders of the Brain: Brain and Behaviour addresses disabilities that occur or have their roots in the early, developmental phase of life which are of utmost concern to parents, siblings, carers and teachers. This text describes the latest clinical and behavioral findings of disorders which largely or entirely involve the frontostriatal (basal ganglia) system including Tourette's, Obsessive-Compulsive and Attention-Deficit-Hyperactivity disorders, Schizophrenia, Autism, gambling and addiction, depression, and Conduct, Developmental Motor Co-ordination, and language disorders. Examples of disorders involving the frontocerebellar are also described such as Asperger's disorder, Williams, Fragile X, and Cerebellar Cognitive Affective syndromes, and Friedreich Ataxia. This book also discusses the relevant anatomy, physiology and pathology, and some of the major functions mediated by affected or relevant structures, together with accounts of the latest recording, brain imaging and stimulating techniques related to these kinds of disorders. Covering both frontostriatal and frontocerebellar, systems which control and direct normal behavior, and which can fail with often distressing consequences during development, as well as addressing behavioural, clinical, pathophysiological and technical aspects, this text is vital to understanding, diagnosis and management of developmental disorders of the brain. This text will be of great interest to clinicians, researchers, teachers and parents.

Nutrients play a significant role in brain development throughout fetal and postnatal life. This book reviews the evidence from animal and human research, highlighting the influence of specific nutrients on brain function and cognitive development. With a unique, integrative approach to the nutritional, environmental, and genetic influences on brain development, the book examines issues such as single versus multiple limiting nutrients, critical periods of deficiency, and the impact of the child-parent relationship on the architecture of the developing brain. The effect of undernutrition on the developing brain of infants and young children can be devastating and enduring. It can impede behavioural and cognitive development and educability, thereby undermining future work productivity. Chapter authors are experts in this field of research and provide an up-to-date insight into the role of the individual nutrients in brain development and function.

Written in a highly-accessible question and answer format, this comprehensive and compassionate guide draws on the latest research, a broad range of expert opinion, numerous real-life voices and personal experiences from people with bipolar. With a list of useful resources, it is both the perfect first port of call and a reference bible you can refer to time and time again.

From how to recognize the symptoms to how to explain to a child that their parent has been diagnosed, first cousins Amanda and Sarah – who have four close family members diagnosed with the condition – explore and explain absolutely everything that someone with bipolar disorder (and those who live with and love them) needs to know.

'A clear, rigorous account of cognitive behavioural methods for treating depression.' - British Journal of Psychiatry The use of behavioural and cognitive techniques for treating depression has yielded exciting results. Cognitive Behaviour Therapy (CBT) is as effective in the short term as anti-depressant drugs and has longer-lasting effects than medication. This book brings together assessment and treatment techniques of proven efficacy, describing them in usable detail and setting them in the context of current psychological theories of depression. It is an invaluable guide to practitioners wishing to make use of CBT.