Your cart is empty
This volume encompasses a variety of topics pertaining to patients with altered levels of consciousness, including valuable differences between disorders. Neurologists, researchers, and clinicians will find a comprehensive accounting of the distinctions between disorders that cause these altered states. Beginning with basic concepts of consciousness and neurobiology, this handbook progresses into more targeted and complex areas of discussion, including important technological advancements that have occurred in neuroimaging.
Neurologists who are frequently called upon for prognostication
and to guide management of patients with these disorders will find
invaluable information, including chapters discussing comatose
states in children and pregnant women, encephalopathic patients,
nutrition disorders, and vegetative and minimally conscious states.
In addition, chapters devoted to philosophical backgrounds and
ethical implications involving patients with impaired
consciousness, are thoroughly presented.
Autonomic dysfunction is a major and poorly understood consequence
of spinal cord injury. It is a cause of very serious disability and
requires much more research. It should be a focus of treatment
strategies. This book will be of interest to anyone involved in
research and treatment of spinal cord injury since it helps to
explain the tremendously negative impact on the body caused by cord
injury that is not as obvious as paralysis and loss of sensation.
It contains a compilation of what is known about bladder,
cardiovascular, bowel and sexual dysfunction after spinal cord
injury, as it relates to the changes within the autonomic nervous
system control of these functions.
Since the late 90 s, a renewed interest in the neurobiology of sleep has provided new advancements in the understanding of basic sleep science and the clinical aspects of sleep disorders, with particular interest given to the role of genetics.
From laboratory techniques and therapies, groundbreaking research in sleep-wakefulness, new models of rapid eye movement (REM) sleep mechanisms, to bright light therapy for circadian rhythm sleep disorders, this handbook will provide clinicians and researchers with a state-of-the-art reference that summarizes the clinical features and management of the many neurological manifestations of sleep disorders.
Practitioners will find invaluable research, information, and
laboratory techniques on such topics as sleep-wake-dependent genes,
the role of sleep duration in mortality and morbidity, and
advancements in the understanding of the neurobiology of sleep
disorders, including narcolepsy-cataplexy, restless legs syndrome,
REM behavior disorders, fatal familiar insomnia, sleep apnea and
heart failure, and nocturnal paroxysmal dystonia, amongst others.
In addition, significant advancements in therapies and drug
protocols are presented.
Neurotrauma is the leading cause of death and disability in young
adults, and the incidence in older patients is increasing.
Neurotrauma is also a field in medicine with one of the highest
unmet needs. Concentrated, focused and multidisciplinary efforts
are required to combat this important disease. Exciting findings
from basic research open opportunities for improving treatment
This volume focuses on the interplay of mind and motion-the bidirectional link between thought and action. In particular, it investigates the implications that this coupling has for decision making. How do we anticipate the consequences of choices and how is the brain able to represent these choice options and their potential consequences? How are different options evaluated and how is a preferred option selected and implemented? This volume addresses these questions not only through an extensive body of knowledge consisting of individual chapters by international experts, but also through integrative group reports that pave a runway into the future. The understanding of how people make decisions is of common interest to experts working in fields such as psychology, economics, movement science, cognitive neuroscience, neuroinformatics, robotics, and sport science. So far, however, it has mainly been advanced in isolation within distinct research disciplines; in contrast, this book results from a deliberate assembly of multidisciplinary teams. It offers intense, focused, and genuine interdisciplinary perspective. It conveys state-of-the-art and outlines future research directions on the hot topic of Mind and Motion (or embodied cognition). It includes contributions from psychologists, neuroscientists, movement scientists, economists, and others.
This volume of "Progress in Brain Research "documents recent
developments and research findings in relation to sex and how the
brain s function and behavior differs from men to women. Specific
areas include cerebral function, morphology and organization,
sexual dimorphism, neural origins, and genetics and epigenetics, as
well as potential causes/affects of stress, pain, sexual
orientation and identity and other social issues such as
distribution of disorders across thesexes and autism.
Leading authors review the state-of-the-art in their field of
investigation, and provide their views and perspectives for future
Leading authors review the state-of-the-art in their field of
investigation, and provide their views and perspectives for future
This issue of Progress in Brain Research is split over 2 volumes,
bringing together cutting-edge research on Functional Neural
Transplantation. The 2 volumes review current knowledge and
understanding, provide a starting point for researchers and
practitioners entering the field, and build a platform for further
research and discovery.
Hardbound. This volume is devoted to Sample Surveys, which is the most widely used method in statistical practice. It covers many theoretical and practical aspects of social and biological investigations, and is a valuable guide for those involved in designing sample surveys.
Serotonin (5-hydroxytryptamine, often cited as 5-HT) is one of the
major excitatory neurotransmitter, and the serotonergic system is
one of the best studied and understood transmitter systems. It is
crucially involved in the organization of virtually all behaviours
and in the regulation of emotion and mood. Alterations in the
serotonergic system, induced by e.g. learning or pathological
processes, underlie behavioural plasticity and changes in mood,
which can finally results in abnormal behaviour and psychiatric
conditions. Not surprisingly, the serotonergic system and its
functional components appear to be targets for a multitude of
pharmacological treatments - examples of very successful drugs
targeting the serotoninergic system include Prozac and Zoloft.
MRI Atlas of Human White Matter remains the only atlas to
provide detailed anatomy of human brain white matter. Knowledge of
this anatomy via diffusion tensor imaging (DTI )greatly enhances
our understanding of brain function and neural connectivity. These
advances promise to be particularly helpful with neurological
diseases, such asAlzheimer's. The second edition offers an
introduction to and description of the methodology, the 3D anatomy
of individual tracts, and a series of color-coded orientation maps
to delineate white matter anatomy in a slice-by-slice manner.
Improvements over the 1st edition include: full segmentation of up
to 176 regions of the brain, added definitions of gray matter to
further understanding between white and gray matter structures,
andthe addition of standardized stereotaxic coordinates. The
atlasserves as avaluable resource for clinicians, researchers and
graduate students in neuroscience, neurology, neurosurgery and
A single volume of 85 articles, the Handbook of the Neurobiology of
Aging is an authoritative selection of relevant chapters from the
Encyclopedia of Neuroscience, the most comprehensive source of
neuroscience information assembled to date (AP Oct 2008).
Episodic memory is the name of the kind of memory that records
personal experiences instead of the mere remembering of impersonal
facts and rules. This type of memory is extremely sensitive to
ageing and disease so an understanding of the mechanisms of
episodic memory might lead to the development of therapies suited
to improve memory in some patient populations. Episodic memory is
unique in that it includes an aspect of self-awareness and helps us
to remember who we are in terms of what we did and what we have
been passed through and what we should do in the future.
This volume provides a broad overview of important new advances in
the field of Neuropharmacology. In 20 chapters, a selection of
international contributors discuss topics including endocannabinoid
function, pain, stress, astrocytes etc, and new possibilities for
treatments of neurological diseases with neuropharmacological
Neuromodulation is an emerging field that explores the use of electrical, chemical, and mechanical interventions to heal neurological deficits. Suchneurostimulation has already shown great promise with disorders and diseases such as chronic pain, epilepsy, and Parkinson s disease. This is the first concise reference covering all of the basic principles of neuromodulation in a single affordable volume for neuro-residents, fellows, and basic clinical practitioners, edited by two prominent clinical experts in the field.
This volume emphasizes essential observations from all of the
important clinical phases involved in any neuromodulation:
targeting, intraoperative assessment, programming, complications,
and complication avoidance. There are commonalities to all
neuromodulation procedures that must be brought to the forefront to
form a cohesive presentation of neuromodulation, and such emphasis
will give readers a more solid grounding in the fundamentals needed
to embrace this field as a cohesive clinical entity.
This volume provides comprehensive information on Parkinson s disease and related disorders, a group of diseases that are among the most common in the field of neurodegenerative study.
Through a high-level presentation of new research regarding these diseases, this handbook will give clinicians and neuroscientists alike a better understanding of the dramatic pharmacological advances made in the management of Parkinson s disease, and the profound observations that have altered the medical community s approach to other degenerative disorders of the nervous system.
Practitioners, researchers, and medical personnel will gain
exciting insights into recent developments that form the basis for
new therapeutic strategies and management protocols for the various
neurological disorders that present with Parkinsonism.
Handbook of Clinical Neurology: Neuro-Oncology, Part II provides an overview of the most recent developments in the field of neuro-oncology, including new diagnostic imaging techniques, along with immunology, molecular biology, and clinical aspects of different types of tumors. It also considers management and new therapeutic strategies for tumors, such as gene therapy, radiation therapy, and molecularly targeted treatments. Divided into five sections encompassing 33 chapters, the book begins with a description of specific tumor types such as low-grade gliomas, anaplastic astrocytomas, and medulloblastoma and primitive neuroectodermal tumors, along with rare brain tumors like neurofibromatosis and other genetic syndromes. It then discusses tumors at special sites, from brainstem tumors to peripheral nerve tumors, tumors of the meninges, and optic, hypothalamic, and thalamic tumors. It also explains the neurological complications of systemic cancer and the adverse effects of some treatments. Clinicians and neuroscientists, as well as researchers who read this book, will gain a better understanding of the clinical features and management of the neurological manifestations of tumors.
This selection of articles from the "Encyclopedia of the Eye"
provides a comprehensive overview of immunological features,
diseases and inflammation of the eye and its support structures and
organs. Rather than taking an immunological focus that is strictly
suitable for clinicians, the volume offers a considerable basic
science background and addresses a broad range of topics - the
immune system of the eye, its various disorders, mechanisms of
inflammation of the eye and visual system, treatment, wound healing
mechanisms, stem cells, and more.
*The first single volume to integrate comparative studies into a comprehensive resource on the neuroscience of ocular immunology
*Chapters are carefully selected from the Encyclopedia of the Eye by the world's leading vision researchers
*The best researchers in the field provide their conclusions in the context of the latest experimental results
Developmental Neuroscience is one of the six core disciplines in Neuroscience, and yet no single volume, non-textbookreference exists on the market that provides researchers with more in-depth, high-levelinformation on developmental neurobiology. Currently, anyone interested in the field at a higher level must sift through review articles published frequently and the more specific handbooks that focus on aspects of development rather than the field as a whole.
This reference is the first of its kind to fill this need. It
pulls together the relevant articles on the topic from the
10-volume Encyclopedia of Neuroscience (Academic Press, 2008) and
serves as an affordable and immediate resource for scientists,
postdocs, graduate students with an interest beyond the basic
textbook materials on the subject.
For over two decades, Paxinos and Watson's The Rat Brain in
Stereotaxic Coordinates, now in its 6th edition, and Franklin and
Paxinos' The Mouse Brain in Stereotaxic Coordinates, now in its 3rd
edition, have been the most used neuroanatomy references for
neuroscientists. Both the illustrations and nomenclature of the
atlas have become standard tools used by almost all research
neuroscientists who deal with anatomy, physiology, or
This fully revised 2e provides the only unified synthesis of
available information concerning the mechanisms of higher-order
memory formation. It spans the range from learning theory, to human
and animal behavioral learning models, to cellular physiology and
biochemistry. It is unique in its incorporation of chapters on
memory disorders, tying in these clinically important syndromes
with the basic science of synaptic plasticity and memory
mechanisms. It also covers cutting-edge approaches such as the use
of genetically engineered animals in studies of memory and memory
diseases. Written in an engaging and easily readable style and
extensively illustrated with many new, full-color figures to help
explain key concepts, this book demystifies the complexities of
memory and deepens the reader s understanding.
Neurological Rehabilitation is the latest volume in the definitive
Handbook of Clinical Neurology series. It is the first time that
this increasing important subject has been included in the series
and this reflects the growing interest and quality of scientific
data on topics around neural recovery and the practical
applications of new research. The volume will appeal to clinicians
from both neurological and rehabilitation backgrounds and contains
topics of interest to all members of the multidisciplinary clinical
team as well as the neuroscience community. The volume is divided
into five key sections. The first is a summary of current research
on neural repair, recovery and plasticity. The authors have kept
the topics readable for a non-scientific audience and focused on
the aspects of basic neuroscience that should be most relevant to
clinical practice. The next section covers the basic principles of
neurorehabilitation, including excellent chapters on learning and
skill acquisition, outcome measurement and functional neuroimaging.
The key clinical section comes next and includes updates and
reviews on the management of the main neurological disabling
physical problems, such as spasticity, pain, sexual functioning and
dysphagia. Cognitive, emotional and behavioural problems are just
as important and are covered in the next section, with excellent
chapters, for example, on memory and management of executive
dysfunction. The final part draws the sections on symptom
management together by discussing the individual diseases that are
most commonly seen in neurorehabilitation and providing an overview
of the management of the disability associated with those
disorders. The volume is a definitive review of current
neurorehabilitation practice and will be valuable to a wide range
of clinicians and scientists working in this rapidly developing
An understanding of mechanisms underlying seizure disorders depends
critically on the insights provided by model systems. In particular
with the development of cellular, molecular, and genetic
investigative tools, there has been an explosion of basic epilepsy
research. Models of Seizures and Epilepsy brings together, for the
first time in 30 years, an overview of the most widely-used models
of seizures and epilepsy. Chapters cover a broad range of
experimental approaches (from in vitro to whole animal
preparations), a variety of epileptiform phenomenology (including
burst discharges and seizures), and suggestions for model
characterization and validation, such as electrographic,
morphologic, pharmacologic, and behavioral features. Experts in the
field provide not only technical reviews of these models but also
conceptual critiques - commenting on the strengths and limitations
of these models, their relationship to clinical phenomenology, and
their value in developing a better understanding and treatments.
Models of Seizures and Epilepsy is a valuable, practical reference
for investigators who are searching for the most appropriate
laboratory models for addressing key questions in the field. It
also provides an important background for physicians, fellows, and
students, offering insight into the potential for advances in
A single volume of 31 articles, Mechanisms of Hormone Actions on
Behavior is an authoritative selection of relevant chapters from
the Hormones Brain and Behavior 2e MRW, the most comprehensive
source of neuroendocrinological information assembled to date (AP
You may like...
The Brain - An Introduction to…
Charles Watson, Matthew Kirkcaldie, … Hardcover
Ocular Periphery and Disorders
Darlene A. Dartt, Peter Bex, … Hardcover
Larry R. Squire, Darwin Berg, … Hardcover R1,843 Discovery Miles 18 430
Quantum Magnetic Resonance Imaging…
Madan M. Kaila, Rakhi Kaila Hardcover
Handbook of Reward and Decision Making
Jean-Claude Dreher, Leon Tremblay Hardcover
Mouse Behavioral Testing - How to Use…
Douglas Wahlsten Hardcover R2,504 Discovery Miles 25 040
Basic Neurochemistry - Principles of…
George J. Siegel, R. Wayne Albers, … Hardcover
Atlas of the Spinal Cord - Mouse, Rat…
Gulgun Sengul, Charles Watson, … Hardcover
Context Effects on Embodied…
Jie Yang Paperback R460 Discovery Miles 4 600
Primer on the Autonomic Nervous System