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Books > Academic & Education > Professional & Technical > Neuroscience

Disorders of Consciousness, Volume 90 (Hardcover, New): G.Bryan Young, Eelco F.M. Wijdicks Disorders of Consciousness, Volume 90 (Hardcover, New)
G.Bryan Young, Eelco F.M. Wijdicks
R6,307 R5,942 Discovery Miles 59 420 Save R365 (6%) Special order

This volume encompasses a variety of topics pertaining to patients with altered levels of consciousness, including valuable differences between disorders. Neurologists, researchers, and clinicians will find a comprehensive accounting of the distinctions between disorders that cause these altered states. Beginning with basic concepts of consciousness and neurobiology, this handbook progresses into more targeted and complex areas of discussion, including important technological advancements that have occurred in neuroimaging.

Neurologists who are frequently called upon for prognostication and to guide management of patients with these disorders will find invaluable information, including chapters discussing comatose states in children and pregnant women, encephalopathic patients, nutrition disorders, and vegetative and minimally conscious states. In addition, chapters devoted to philosophical backgrounds and ethical implications involving patients with impaired consciousness, are thoroughly presented.
* A comprehensive reference guide that progresses from basic concepts of consciousness and neurobiology to targeted, complex topics of discussion
* Invaluable information on new technological advancements that have occurred in neuroimaging, thus furthering diagnostic and treatment modalities
* Philosophical and ethical implications involving the relationship between clinicians and patients with impaired levels of consciousness

Autonomic Dysfunction After Spinal Cord Injury, Volume 152 (Hardcover): Lynne C. Weaver, Canio Polosa Autonomic Dysfunction After Spinal Cord Injury, Volume 152 (Hardcover)
Lynne C. Weaver, Canio Polosa
R4,451 R4,203 Discovery Miles 42 030 Save R248 (6%) Special order

Autonomic dysfunction is a major and poorly understood consequence of spinal cord injury. It is a cause of very serious disability and requires much more research. It should be a focus of treatment strategies. This book will be of interest to anyone involved in research and treatment of spinal cord injury since it helps to explain the tremendously negative impact on the body caused by cord injury that is not as obvious as paralysis and loss of sensation. It contains a compilation of what is known about bladder, cardiovascular, bowel and sexual dysfunction after spinal cord injury, as it relates to the changes within the autonomic nervous system control of these functions.
The book begins with a description of the time course of autonomic dysfunctions and their ramifications from the first hours after a spinal cord injury to the more stable chronic states. The next section contains three chapters that address anatomical findings that may provide some of the foundation for autonomic dysfunctions in many of the systems. The system-specific chapters then follow in four sections. Each section begins with a chapter or two defining the clinical problems experienced by people with cord injury. The following chapters present research, basic and clinical, that address the autonomic dysfunctions.

Sleep Disorders Part I, Volume 98 (Hardcover): Pasquale Montagna, Sudhansu Chokroverty Sleep Disorders Part I, Volume 98 (Hardcover)
Pasquale Montagna, Sudhansu Chokroverty
R4,605 R4,350 Discovery Miles 43 500 Save R255 (6%) Special order

Since the late 90 s, a renewed interest in the neurobiology of sleep has provided new advancements in the understanding of basic sleep science and the clinical aspects of sleep disorders, with particular interest given to the role of genetics.

From laboratory techniques and therapies, groundbreaking research in sleep-wakefulness, new models of rapid eye movement (REM) sleep mechanisms, to bright light therapy for circadian rhythm sleep disorders, this handbook will provide clinicians and researchers with a state-of-the-art reference that summarizes the clinical features and management of the many neurological manifestations of sleep disorders.

Practitioners will find invaluable research, information, and laboratory techniques on such topics as sleep-wake-dependent genes, the role of sleep duration in mortality and morbidity, and advancements in the understanding of the neurobiology of sleep disorders, including narcolepsy-cataplexy, restless legs syndrome, REM behavior disorders, fatal familiar insomnia, sleep apnea and heart failure, and nocturnal paroxysmal dystonia, amongst others. In addition, significant advancements in therapies and drug protocols are presented.
* Clinical data on groundbreaking advancements in the understanding of basic sleep science
* Invaluable information on new therapies and drug protocols for sleep disorders
* A state-of-the-art reference that includes the role of genetics in sleep medicine"

Neurotrauma: New Insights into Pathology and Treatment, Volume 161 (Hardcover, 161st edition): John T. Weber, Andrew I. R. Maas Neurotrauma: New Insights into Pathology and Treatment, Volume 161 (Hardcover, 161st edition)
John T. Weber, Andrew I. R. Maas
R4,999 R4,716 Discovery Miles 47 160 Save R283 (6%) Special order

Neurotrauma is the leading cause of death and disability in young adults, and the incidence in older patients is increasing. Neurotrauma is also a field in medicine with one of the highest unmet needs. Concentrated, focused and multidisciplinary efforts are required to combat this important disease. Exciting findings from basic research open opportunities for improving treatment results.
This volume presents a unique and comprehensive overview of the latest findings and insights on translational research in neurotrauma. This book should be a must for any TBI or SCI researcher interested in translating their work to the clinic, as well as to clinicians interested in the latest research findings which could provide novel treatment strategies for their patients.
- Integrates results from research on traumatic brain injury and spinal cord injury, bridging basic science and clinical research
- Includes contributions from worldwide panel of leading researchers and clinicians in the fields of TBI and SCI

Breathe, Walk and Chew, Volume 187 - The Neural Challenge: Part I (Hardcover, New): Jean-Pierre Gossard, Rejean Dubuc, Arlette... Breathe, Walk and Chew, Volume 187 - The Neural Challenge: Part I (Hardcover, New)
Jean-Pierre Gossard, Rejean Dubuc, Arlette Kolta
R4,673 R4,408 Discovery Miles 44 080 Save R265 (6%) Special order

This volume focuses on the interplay of mind and motion-the bidirectional link between thought and action. In particular, it investigates the implications that this coupling has for decision making. How do we anticipate the consequences of choices and how is the brain able to represent these choice options and their potential consequences? How are different options evaluated and how is a preferred option selected and implemented? This volume addresses these questions not only through an extensive body of knowledge consisting of individual chapters by international experts, but also through integrative group reports that pave a runway into the future. The understanding of how people make decisions is of common interest to experts working in fields such as psychology, economics, movement science, cognitive neuroscience, neuroinformatics, robotics, and sport science. So far, however, it has mainly been advanced in isolation within distinct research disciplines; in contrast, this book results from a deliberate assembly of multidisciplinary teams. It offers intense, focused, and genuine interdisciplinary perspective. It conveys state-of-the-art and outlines future research directions on the hot topic of Mind and Motion (or embodied cognition). It includes contributions from psychologists, neuroscientists, movement scientists, economists, and others.

Sex Differences in the Human Brain, their underpinnings and implications, Volume 186 (Hardcover): Ivanka Savic-Berglund Sex Differences in the Human Brain, their underpinnings and implications, Volume 186 (Hardcover)
Ivanka Savic-Berglund
R4,669 R4,404 Discovery Miles 44 040 Save R265 (6%) Special order

This volume of "Progress in Brain Research "documents recent developments and research findings in relation to sex and how the brain s function and behavior differs from men to women. Specific areas include cerebral function, morphology and organization, sexual dimorphism, neural origins, and genetics and epigenetics, as well as potential causes/affects of stress, pain, sexual orientation and identity and other social issues such as distribution of disorders across thesexes and autism.
* Informs and updates on all the latest developments in the field
* Highlights areas for future research
* Contributions from leading authorities and industry experts"

The Neurobiology of Circadian Timing, Volume 199 (Hardcover, New): A. Kalsbeek, Martha Merrow, Till Roenneberg, Russell G.... The Neurobiology of Circadian Timing, Volume 199 (Hardcover, New)
A. Kalsbeek, Martha Merrow, Till Roenneberg, Russell G. Foster
R4,422 R4,175 Discovery Miles 41 750 Save R247 (6%) Special order

Leading authors review the state-of-the-art in their field of investigation, and provide their views and perspectives for future research
Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered
All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist
Leading authors review the state-of-the-art in their field of investigation, and provide their views and perspectives for future research
Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered
All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist

Orexin/Hypocretin System, Volume 198 (Hardcover, New): Anantha Shekhar Orexin/Hypocretin System, Volume 198 (Hardcover, New)
Anantha Shekhar
R4,385 R4,138 Discovery Miles 41 380 Save R247 (6%) Special order

Leading authors review the state-of-the-art in their field of investigation, and provide their views and perspectives for future research
Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered
All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist
Leading authors review the state-of-the-art in their field of investigation, and provide their views and perspectives for future research
Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered
All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist

Functional Neural Transplantation III, Volume 201 - Primary and Stem Cell Therapies for Brain Repair, Part II (Hardcover, New):... Functional Neural Transplantation III, Volume 201 - Primary and Stem Cell Therapies for Brain Repair, Part II (Hardcover, New)
Stephen B. Dunnett, Anders Bjorklund
R4,409 R4,162 Discovery Miles 41 620 Save R247 (6%) Special order

This issue of Progress in Brain Research is split over 2 volumes, bringing together cutting-edge research on Functional Neural Transplantation. The 2 volumes review current knowledge and understanding, provide a starting point for researchers and practitioners entering the field, and build a platform for further research and discovery.
Leading authors review the state-of-the-art in their field of investigation, and provide their views and perspectives for future research
Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered
All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist

Sampling, Volume 6 (Hardcover): P.R. Krishnaiah# Sampling, Volume 6 (Hardcover)
P.R. Krishnaiah#; Volume editing by Paruchuri R. Krishnaiah, C.Radhakrishna Rao
R1,120 Discovery Miles 11 200 Special order

Hardbound. This volume is devoted to Sample Surveys, which is the most widely used method in statistical practice. It covers many theoretical and practical aspects of social and biological investigations, and is a valuable guide for those involved in designing sample surveys.

Handbook of the Behavioral Neurobiology of Serotonin, Volume 21 (Hardcover): Christian P. Muller, Barry Jacobs Handbook of the Behavioral Neurobiology of Serotonin, Volume 21 (Hardcover)
Christian P. Muller, Barry Jacobs
R3,468 R3,285 Discovery Miles 32 850 Save R183 (5%) Special order

Serotonin (5-hydroxytryptamine, often cited as 5-HT) is one of the major excitatory neurotransmitter, and the serotonergic system is one of the best studied and understood transmitter systems. It is crucially involved in the organization of virtually all behaviours and in the regulation of emotion and mood. Alterations in the serotonergic system, induced by e.g. learning or pathological processes, underlie behavioural plasticity and changes in mood, which can finally results in abnormal behaviour and psychiatric conditions. Not surprisingly, the serotonergic system and its functional components appear to be targets for a multitude of pharmacological treatments - examples of very successful drugs targeting the serotoninergic system include Prozac and Zoloft.
The last decades of research have not only fundamentally expanded our view on serotonin but also revealed in much more detail an astonishing complexity of this system, which comprises a multitude of receptors and signalling pathways. A detailed view on its role in basal, but also complex, behaviours emerged, and, was presented in a number of single review articles. Although much is known now, the serotonergic system is still a fast growing field of research contributing to our present understanding of the brains function during normal and disturbed behaviour.
This handbook aims towards a detailed and comprehensive overview over the many facets of behavioural serotonin research. As such, it will provide the most up to date and thorough reading concerning the serotonergic systems control of behaviour and mood in animals and humans. The goal is to create a systematic overview and first hand reference that can be used by students and scholars alike in the fields of genetics, anatomy, pharmacology, physiology, behavioural neuroscience, pathology, and psychiatry. The chapters in this book will be written by leading scientists in this field. Most of them have already written excellent reviews in their field of expertise.
The book is divided in 4 sections. After an historical introduction, illustrating the growth of ideas about serotonin function in behaviour of the last forty years, section A will focus on the functional anatomy of the serotonergic system. Section B provides a review of the neurophysiology of the serotonergic system and its single components. In section C the involvement of serotonin in behavioural organization will be discussed in great detail, while section D deals with the role of serotonin in behavioural pathologies and psychiatric disorders.

* The first handbook broadly discussing the behavioral neurobiology of the serotonorgic transmitter system
* Co-edited by one of the pioneers and opinion leaders of the past decades, Barry Jacobs (Princeton), with an international list (10 countries) of highly regarded contributors providing over 50 chapters, and including the leaders in the field in number of articles and citations: K. P. Lesch, T. Sharp, A. Caspi, P. Blier, G.K. Aghajanian, E. C. Azmitia, and others
* The only integrated and complete resource on the market containing the best information integrating international research, providing a global perspective to an international community.
* Of great value not only for researchers and experts, but also for students and clinicians as a background reference.

MRI Atlas of Human White Matter (Hardcover, 2nd edition): Kenichi Oishi, Andreia V. Faria, Peter C. M. Van Zijl, Susumu Mori MRI Atlas of Human White Matter (Hardcover, 2nd edition)
Kenichi Oishi, Andreia V. Faria, Peter C. M. Van Zijl, Susumu Mori
R3,543 R3,351 Discovery Miles 33 510 Save R192 (5%) Special order

MRI Atlas of Human White Matter remains the only atlas to provide detailed anatomy of human brain white matter. Knowledge of this anatomy via diffusion tensor imaging (DTI )greatly enhances our understanding of brain function and neural connectivity. These advances promise to be particularly helpful with neurological diseases, such asAlzheimer's. The second edition offers an introduction to and description of the methodology, the 3D anatomy of individual tracts, and a series of color-coded orientation maps to delineate white matter anatomy in a slice-by-slice manner. Improvements over the 1st edition include: full segmentation of up to 176 regions of the brain, added definitions of gray matter to further understanding between white and gray matter structures, andthe addition of standardized stereotaxic coordinates. The atlasserves as avaluable resource for clinicians, researchers and graduate students in neuroscience, neurology, neurosurgery and radiology.
Visualization of brain white matter anatomy via 3D diffusion tensor imaging (DTI) contrasts and enhances relationship of anatomy to functionFull segmentation of 170+ brain regions more clearly defines structure boundaries than previous point-and-annotate anatomical labeling, andconnectivity is mapped in a way not provided by traditional atlasesElectronic files with viewing software can be made available via CD and/or BrainNavigator, allowing readers access to raw image files"

Handbook of the Neuroscience of Aging (Hardcover, New): Patrick R. Hof, Charles V. Mobbs Handbook of the Neuroscience of Aging (Hardcover, New)
Patrick R. Hof, Charles V. Mobbs
R3,296 R3,123 Discovery Miles 31 230 Save R173 (5%) Special order

A single volume of 85 articles, the Handbook of the Neurobiology of Aging is an authoritative selection of relevant chapters from the Encyclopedia of Neuroscience, the most comprehensive source of neuroscience information assembled to date (AP Oct 2008).
The study of neural aging is a central topic in neuroscience, neuropsychology and gerontology. Some well-known age-related neurological diseases include Parkinson's and Alzheimer's, but even more common are problems of aging which are not due to disease but to more subtle impairments in neurobiological systems, including impairments in vision, memory loss, muscle weakening, and loss of reproductive functions, changes in body weight, and sleeplessness. As the average age of our society increases, diseases of aging become more common and conditions associated with aging need more attention by doctors and researchers.
This book offers an overview of topics related to neurobiological impairments which are related to the aging brain and nervous system. Coverage ranges from animal models to human imaging, fundamentals of age-related neural changes and pathological neurodegeneration, and offers an overview of structural and functional changes at the molecular, systems, and cognitive levels. Key pathologies such as memory disorders, Alzheimer's, dementia, Down syndrome, Parkinson's, and stroke are discussed, as are cutting edge interventions such as cell replacement therapy and deep brain stimulation. There is no other current single-volume reference with such a comprehensive coverage and depth.
Authors selected are the internationally renowned experts for the particular topics on which they write, and the volume is richly illustrated with over 100 color figures. A collection of articles reviewing our fundamental knowledge of neural aging, the book provides an essential, affordable reference for scientists in all areas of Neuroscience, Neuropsychology and Gerontology.
* The most comprehensive source of up-to-date data on the neurobiology of aging, review articles cover: normal, sensory and cognitive aging; neuroendocrine, structural and molecular factors; and fully address both patholgy and intervention
* Chapters represent an authoritative selection of relevant material from the most comprehensive source of information about neuroscience ever assembled, (Encyclopedia of Neuroscience), synthesizing information otherwise
dispersed across a number of journal articles and book chapters, and saving researchers the time consuming process of finding and integrating this information themselves
* Offering outstanding scholarship, each chapter is written by an expert in the topic area and over 20% of chapters feature international contributors, (representing 11 countries)
* Provides more fully vetted expert knowledge than any existing work with broad appeal for the US, UK and Europe, accurately crediting the contributions to research in those regions
* Fully explores various pathologies associated with the aging brain (Alzheimer's, dementia, Parkinson's, memory disorders, stroke, Down's syndrome, etc.)
* Coverage of disorders and key interventions makes the volume relevant to clinicians as well as researchers
* Heavily illustrated with over 100 color figures

Handbook of Episodic Memory, Volume 18 (Hardcover): Ekrem Dere, Alexander Easton, Lynn Nadel, Joe P. Huston Handbook of Episodic Memory, Volume 18 (Hardcover)
Ekrem Dere, Alexander Easton, Lynn Nadel, Joe P. Huston
R3,116 R2,953 Discovery Miles 29 530 Save R163 (5%) Special order

Episodic memory is the name of the kind of memory that records personal experiences instead of the mere remembering of impersonal facts and rules. This type of memory is extremely sensitive to ageing and disease so an understanding of the mechanisms of episodic memory might lead to the development of therapies suited to improve memory in some patient populations. Episodic memory is unique in that it includes an aspect of self-awareness and helps us to remember who we are in terms of what we did and what we have been passed through and what we should do in the future.
This book brings together a renowned team of contributors from the fields of cognitive psychology, neuropsychology and behavioural and molecular neuroscience. It provides a detailed and comprehensive overview of recent developments in understanding human episodic memory and animal episodic-like memory in terms of concepts, methods, mechanisms, neurobiology and pathology. The work presented within this book will have a profound effect on the direction that future research in this topic will take.
- The first and most current comprehensive handbook on what we know about episodic memory, the memory of events, time, place, and emotion, and a key feature of awareness and consciousness
- Articles summarize our understanding of the mechanisms of episodic memory as well as surveying the neurobiology of epsidodic memory in patients, animal studies and functional imaging work
- Includes 34 heavily illustrated chapters in two sections by the leading scientists in the field

Advances in Neuropharmacology, Volume 85 (Hardcover): Giacinto Bagetta, M. Tiziana Corasaniti, T. Sakurada, S. Sakurada Advances in Neuropharmacology, Volume 85 (Hardcover)
Giacinto Bagetta, M. Tiziana Corasaniti, T. Sakurada, S. Sakurada
R4,128 Discovery Miles 41 280 Special order

This volume provides a broad overview of important new advances in the field of Neuropharmacology. In 20 chapters, a selection of international contributors discuss topics including endocannabinoid function, pain, stress, astrocytes etc, and new possibilities for treatments of neurological diseases with neuropharmacological approaches.
- Cutting-edge articles in neuropharmacology
- Discusses new possibilities for treatments of neurological disorders
- Very international authorship providing a global view of the state of research

Essential Neuromodulation (Hardcover): Jeffrey E. Arle, Jay L. Shils Essential Neuromodulation (Hardcover)
Jeffrey E. Arle, Jay L. Shils
R3,045 Discovery Miles 30 450 Special order

Neuromodulation is an emerging field that explores the use of electrical, chemical, and mechanical interventions to heal neurological deficits. Suchneurostimulation has already shown great promise with disorders and diseases such as chronic pain, epilepsy, and Parkinson s disease. This is the first concise reference covering all of the basic principles of neuromodulation in a single affordable volume for neuro-residents, fellows, and basic clinical practitioners, edited by two prominent clinical experts in the field.

This volume emphasizes essential observations from all of the important clinical phases involved in any neuromodulation: targeting, intraoperative assessment, programming, complications, and complication avoidance. There are commonalities to all neuromodulation procedures that must be brought to the forefront to form a cohesive presentation of neuromodulation, and such emphasis will give readers a more solid grounding in the fundamentals needed to embrace this field as a cohesive clinical entity.
Chapters offer point-counterpoint commentary for varied perspectivesAppendix distills current guidelines in easy, accessible formatChapters follow story of patient care, effectively emphasizing general principles with supporting examplesOffers outstanding scholarship, with over 20% of chapters involving international contributors"

Parkinson's Disease and Related Disorders, Part II, Volume 84 (Hardcover): William C. Koller, Eldad Melamed Parkinson's Disease and Related Disorders, Part II, Volume 84 (Hardcover)
William C. Koller, Eldad Melamed
R7,097 Discovery Miles 70 970 Special order

This volume provides comprehensive information on Parkinson s disease and related disorders, a group of diseases that are among the most common in the field of neurodegenerative study.

Through a high-level presentation of new research regarding these diseases, this handbook will give clinicians and neuroscientists alike a better understanding of the dramatic pharmacological advances made in the management of Parkinson s disease, and the profound observations that have altered the medical community s approach to other degenerative disorders of the nervous system.

Practitioners, researchers, and medical personnel will gain exciting insights into recent developments that form the basis for new therapeutic strategies and management protocols for the various neurological disorders that present with Parkinsonism.
* A comprehensive resource on new advancements in the field of Parkinson s research and related neurodegenerative diseases
* Important information on dramatic pharmacological advances in the management of Parkinson s disease
* A platform to stimulate new research and better understanding of these common and disabling neurological disorders"

Neuro-Oncology, Part II, Volume 105 (Hardcover): Wolfgang Grisold, Riccardo Soffietti Neuro-Oncology, Part II, Volume 105 (Hardcover)
Wolfgang Grisold, Riccardo Soffietti
R4,698 Discovery Miles 46 980 Special order

Handbook of Clinical Neurology: Neuro-Oncology, Part II provides an overview of the most recent developments in the field of neuro-oncology, including new diagnostic imaging techniques, along with immunology, molecular biology, and clinical aspects of different types of tumors. It also considers management and new therapeutic strategies for tumors, such as gene therapy, radiation therapy, and molecularly targeted treatments. Divided into five sections encompassing 33 chapters, the book begins with a description of specific tumor types such as low-grade gliomas, anaplastic astrocytomas, and medulloblastoma and primitive neuroectodermal tumors, along with rare brain tumors like neurofibromatosis and other genetic syndromes. It then discusses tumors at special sites, from brainstem tumors to peripheral nerve tumors, tumors of the meninges, and optic, hypothalamic, and thalamic tumors. It also explains the neurological complications of systemic cancer and the adverse effects of some treatments. Clinicians and neuroscientists, as well as researchers who read this book, will gain a better understanding of the clinical features and management of the neurological manifestations of tumors.

Immunology, Inflammation and Diseases of the Eye (Hardcover): Darlene A. Dartt, Reza Dana, Patricia A. D'Amore, J y... Immunology, Inflammation and Diseases of the Eye (Hardcover)
Darlene A. Dartt, Reza Dana, Patricia A. D'Amore, J y Niederkorn
R3,219 Discovery Miles 32 190 Special order

This selection of articles from the "Encyclopedia of the Eye" provides a comprehensive overview of immunological features, diseases and inflammation of the eye and its support structures and organs. Rather than taking an immunological focus that is strictly suitable for clinicians, the volume offers a considerable basic science background and addresses a broad range of topics - the immune system of the eye, its various disorders, mechanisms of inflammation of the eye and visual system, treatment, wound healing mechanisms, stem cells, and more.

*The first single volume to integrate comparative studies into a comprehensive resource on the neuroscience of ocular immunology

*Chapters are carefully selected from the Encyclopedia of the Eye by the world's leading vision researchers

*The best researchers in the field provide their conclusions in the context of the latest experimental results

Developmental Neurobiology (Hardcover): Greg Lemke Developmental Neurobiology (Hardcover)
Greg Lemke
R3,969 Discovery Miles 39 690 Special order

Developmental Neuroscience is one of the six core disciplines in Neuroscience, and yet no single volume, non-textbookreference exists on the market that provides researchers with more in-depth, high-levelinformation on developmental neurobiology. Currently, anyone interested in the field at a higher level must sift through review articles published frequently and the more specific handbooks that focus on aspects of development rather than the field as a whole.

This reference is the first of its kind to fill this need. It pulls together the relevant articles on the topic from the 10-volume Encyclopedia of Neuroscience (Academic Press, 2008) and serves as an affordable and immediate resource for scientists, postdocs, graduate students with an interest beyond the basic textbook materials on the subject.
The first and only comprehensive, single-volume reference for developmental neuroscience that goes beyond the basic textbook informationThe 93 chapters cover topics ranging from cell fate determination, path finding, synapse generation, neural stem cells, to neurodegeneration and regeneration, carefully selected from the "Encyclopedia of Neuroscience" by one of the great developmental neuroscientists, Greg LemkeThe best researchers in the field provide their conclusions in the context of the latest experimental results"

Chemoarchitectonic Atlas of the Mouse Brain (Hardcover): George Paxinos, Charles Watson Chemoarchitectonic Atlas of the Mouse Brain (Hardcover)
George Paxinos, Charles Watson
R6,300 Discovery Miles 63 000 Special order

For over two decades, Paxinos and Watson's The Rat Brain in Stereotaxic Coordinates, now in its 6th edition, and Franklin and Paxinos' The Mouse Brain in Stereotaxic Coordinates, now in its 3rd edition, have been the most used neuroanatomy references for neuroscientists. Both the illustrations and nomenclature of the atlas have become standard tools used by almost all research neuroscientists who deal with anatomy, physiology, or function.
This new atlas represents the first time an accurate histochemical atlas showing the areas of the mouse brain in microscopic slides in a variety of different stains has been available. Until now researchers studying the mouse brain have been forced to consult the existing histochemical atlases of the rat brain (including Paxinos and Watson's) and extrapolate from rat data - a strategy which is not very accurate and often not successful. This atlas collects systematic images of the mouse brain stained with a range of key chemical markers to complement The Mouse Brain in Stereotaxic Coordinates.
* 350 sections of the mouse brain, stained serially with Nissl and six chemical markers (parvalbumin, calbindin, calretinin, tyrosine hydroxylase, NADPH diaphorase, and GAD)
* Features diagrams in addition to the sections
* Sections are labelled on the photographs
* Newly developed format showing 7 photographs and one diagram on each open book page in a 14"x11" format facilitates use in the laboratory
* Fills a huge gap in detailed information on the mouse brain
* Features neuromeric borders based on the system developed in Puelles et al. Atlas of the Chick Brain in Stereotaxic Coordinates (2007)
* The perfect partner to the stereotaxic atlases and references published by Elsevier

Mechanisms of Memory (Hardcover, 2nd edition): J. David Sweatt Mechanisms of Memory (Hardcover, 2nd edition)
J. David Sweatt
R2,366 Discovery Miles 23 660 Special order

This fully revised 2e provides the only unified synthesis of available information concerning the mechanisms of higher-order memory formation. It spans the range from learning theory, to human and animal behavioral learning models, to cellular physiology and biochemistry. It is unique in its incorporation of chapters on memory disorders, tying in these clinically important syndromes with the basic science of synaptic plasticity and memory mechanisms. It also covers cutting-edge approaches such as the use of genetically engineered animals in studies of memory and memory diseases. Written in an engaging and easily readable style and extensively illustrated with many new, full-color figures to help explain key concepts, this book demystifies the complexities of memory and deepens the reader s understanding.
More than 25% new content, particularly expanding the scope to include new findings in translational research. Unique in its depth of coverage of molecular and cellular mechanisms Extensive cross-referencing to Comprehensive Learning and Memory Discusses clinically relevant memory disorders in the context of modern molecular research and includes numerous practical examples
"

Neurological Rehabilitation, Volume 110 (Hardcover, New): Michael P. Barnes, David C. Good Neurological Rehabilitation, Volume 110 (Hardcover, New)
Michael P. Barnes, David C. Good
R5,450 Discovery Miles 54 500 Special order

Neurological Rehabilitation is the latest volume in the definitive Handbook of Clinical Neurology series. It is the first time that this increasing important subject has been included in the series and this reflects the growing interest and quality of scientific data on topics around neural recovery and the practical applications of new research. The volume will appeal to clinicians from both neurological and rehabilitation backgrounds and contains topics of interest to all members of the multidisciplinary clinical team as well as the neuroscience community. The volume is divided into five key sections. The first is a summary of current research on neural repair, recovery and plasticity. The authors have kept the topics readable for a non-scientific audience and focused on the aspects of basic neuroscience that should be most relevant to clinical practice. The next section covers the basic principles of neurorehabilitation, including excellent chapters on learning and skill acquisition, outcome measurement and functional neuroimaging. The key clinical section comes next and includes updates and reviews on the management of the main neurological disabling physical problems, such as spasticity, pain, sexual functioning and dysphagia. Cognitive, emotional and behavioural problems are just as important and are covered in the next section, with excellent chapters, for example, on memory and management of executive dysfunction. The final part draws the sections on symptom management together by discussing the individual diseases that are most commonly seen in neurorehabilitation and providing an overview of the management of the disability associated with those disorders. The volume is a definitive review of current neurorehabilitation practice and will be valuable to a wide range of clinicians and scientists working in this rapidly developing field.
*A volume in the Handbook of Clinical Neurology series, which has an unparalleled reputation as the world's most comprehensive source of information in neurology.
*International list of contributors including the leading workers in the field.
*Describes the advances which have occurred in clinical neurology and the neurosciences, their impact on the understanding of neurological disorders and on patient care.

Models of Seizures and Epilepsy (Hardcover, New): Asla Pitkanen, Philip A. Schwartzkroin, Solomon L. Moshe Models of Seizures and Epilepsy (Hardcover, New)
Asla Pitkanen, Philip A. Schwartzkroin, Solomon L. Moshe
R4,883 Discovery Miles 48 830 Special order

An understanding of mechanisms underlying seizure disorders depends critically on the insights provided by model systems. In particular with the development of cellular, molecular, and genetic investigative tools, there has been an explosion of basic epilepsy research. Models of Seizures and Epilepsy brings together, for the first time in 30 years, an overview of the most widely-used models of seizures and epilepsy. Chapters cover a broad range of experimental approaches (from in vitro to whole animal preparations), a variety of epileptiform phenomenology (including burst discharges and seizures), and suggestions for model characterization and validation, such as electrographic, morphologic, pharmacologic, and behavioral features. Experts in the field provide not only technical reviews of these models but also conceptual critiques - commenting on the strengths and limitations of these models, their relationship to clinical phenomenology, and their value in developing a better understanding and treatments. Models of Seizures and Epilepsy is a valuable, practical reference for investigators who are searching for the most appropriate laboratory models for addressing key questions in the field. It also provides an important background for physicians, fellows, and students, offering insight into the potential for advances in epilepsy research.
. The first comprehensive description of animal models of epilepsy since the early 1970's
. Comprehensive analysis of "What the models model" to guide the selection of each model, and what specific questions it will answer
. Elegant examples of the use of novel technologies that can be applied in experimental epilepsy research
. World expert opinions on the clinical relevance of each model"

Molecular Mechanisms of Hormone Actions on Behavior (Hardcover, New): Anne M. Etgen, Donald W. Pfaff Molecular Mechanisms of Hormone Actions on Behavior (Hardcover, New)
Anne M. Etgen, Donald W. Pfaff
R4,869 Discovery Miles 48 690 Special order

A single volume of 31 articles, Mechanisms of Hormone Actions on Behavior is an authoritative selection of relevant chapters from the Hormones Brain and Behavior 2e MRW, the most comprehensive source of neuroendocrinological information assembled to date (AP June 2009).
The study of hormones as they impact the brain and, subsequently, behavior is a central topic in neuroscience, endocrinology and psychiatry. This volume offers an overview of neuroendocrinological topics, approaching the subject from the perspective of the mechanisms which control hormone actions on behavior. Female, male and stress hormones are discussed at the cellular, behavioral and developmental level, and sexual differentiation of the development of hormone-dependent neuronal systems, neuropeptides/neuromodulators, and steroid-inducedneuroplasticity are addressed. There is simply no other current single-volume reference with such comprehensive coverage and depth.
Authors selected are the internationally renowned experts for the particular topics on which they write, and the volume is richly illustrated with over 175 figures (over 50 in color). A collection of articles reviewing our fundamental knowledge of the mechanisms of neuroendocrinology, the book provides an essential, affordable reference for researchers, clinicians and graduate students in the area.
- The most comprehensive single-volume source of up-to-date data on the mechanisms behind neuroendocrinology, with review articles covering x, y z
- Chapters synthesize information otherwise dispersed across a number of journal articles and book chapters, thus saving researchers the time consuming process of finding and integrating this information themselves
- Offering outstanding scholarship, each chapter is written by an expert in the topic area and approximately 35% of chapters are written by international contributors
- Provides more fully vetted expert knowledge than any existing work with broad appeal for the US, UK and Europe, accurately crediting the contributions to research in those regions
- Heavily illustrated with 175 figures, approximately 54 in color
- Presents material in most visually useful form for the reader

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