Modern cancer research is a high-tech undertaking, overlapping with many fields in the physical sciences. These include nanotechnology, engineering, immunology, and bioinformatics. This book focuses on the science and technology underlying the diagnosis and treatement of cancer. The authors offer insights into technologies including radiotherapy, modelling, and drug encapsulation.

This book presents proton-3He elastic scattering experiments conducted at intermediate energies, with the aim of identifying three-nucleon force (3NF) effects in a four-nucleon scattering system. The 3NF plays an essential part in understanding various nuclear phenomena, and few-nucleon scatterings further offers a good opportunity to study the dynamical aspects of 3NFs. In particular, proton-3He scattering is one of the most promising approaches to an iso-spin dependence of 3NFs. The book in-depth explains the achieved development of polarized 3He target system for the proton-3He scattering experiments, and describes successful precise evaluation of the target polarization. The experiments yielded the first precise data for this system and offer a valuable resource for the study of 3NFs.

This book presents a detailed look at experimental and computational techniques for accurate structure determination of free molecules. The most fundamental property of a molecule is its structure - it is a prerequisite for determining and understanding most other important properties of molecules. The determination of accurate structures is hampered by a myriad of factors, subjecting the collected data to non-negligible systematic errors. This book explains the origin of these errors and how to mitigate and even avoid them altogether. It features a detailed comparison of the different experimental and computation methods, explaining their interplay and the advantages of their combined use. Armed with this information, the reader will be able to choose the appropriate methods to determine - to a great degree of accuracy - the relevant molecular structure.

Recent advances witness the potential to employ nanomedicine and game-changing methods to deliver drug molecules directly to diseased sites. To optimize and then enhance the efficacy and specificity, the control and guidance of drug carriers in vasculature has become crucial. Current bottlenecks in the optimal design of drug carrying particles are the lack of knowledge about the transport of particles, adhesion on endothelium wall and subsequent internalization into diseased cells. To study the transport and adhesion of particle in vasculature, the authors have made great efforts to numerically investigate the dynamic and adhesive motions of particles in the blood flow. This book discusses the recent achievements from the establishment of fundamental physical problem to development of multiscale model, and finally large scale simulations for understanding transport of particle-based drug carriers in blood flow.

Der 4. Juli 2012 stellt ein historisches Datum fur das Europaische Kernforschungszentrum CERN in Genf dar: die Verkundung der Entdeckung des letzten, vorhergesagten, noch fehlenden und lange gesuchten Elementarteilchens, des Higgs-Bosons. Ein Jahr spater kommen im Rahmen der Konferenz des Zentrums fur interdisziplinare Forschung (ZiF) in Bielefeld eine Vielzahl der mit dem Grossprojekt am CERN verbundenen Wissenschaftler zusammen, um nicht nur uber die Entdeckung des Teilchens, sondern vor allem uber die Realisierung und Bedeutung eines derart ungeheuren Unterfangens fur solch ein wissenschaftliches Grossprojekt zu berichten. Der Generaldirektor des CERN, Prof. Dr. Rolf-Dieter Heuer, liefert in seinem Eroeffnungsvortrag die Grundlage fur die Diskussion der vielerlei Aspekte, die dabei ins Spiel kommen. So finden sich im vorliegenden Band zum einen Berichte uber die Grossforschung selbst: von der Entdeckung des Higgs-Teilchens uber die Erforschung des Quark-Gluon-Plasmas und die Bedeutung von Theorien der Neuen Physik, wie der Supersymmetrie, bis hin zur Gefahr durch Schwarze Mikroloecher. Zum anderen werden Themen werden Themen wie der Bau und die Finanzierung von Grossprojekten, wie dem LHC am CERN oder dem FAIR in Darmstadt, naher beleuchtet. Daruber hinaus bereichern Beitrage uber die philosophischen Aspekte und kulturellen bzw. gesellschaftlichen Auswirkungen der wissenschaftlichen Grossforschung am LHC den interdisziplinaren Austausch um weitere Perspektiven. Durch eine Vielzahl an Informationsboxen werden dem Leser relevante Hintergrunde und die notwendigen physikalischen Sachverhalte nahergebracht.

This carefully researched book presents facts and arguments showing, beyond a doubt, that nuclear fusion power will not be technically feasible in time to satisfy the world's urgent need for climate-neutral energy. The author describes the 70-year history of nuclear fusion; the vain attempts to construct an energy-generating nuclear fusion power reactor, and shows that even in the most optimistic scenario nuclear fusion, in spite of the claims of its proponents, will not be able to make a sizable contribution to the energy mix in this century, whatever the outcome of ITER. This implies that fusion power will not be a factor in combating climate change, and that the race to save the climate with carbon-free energy will have been won or lost long before the first nuclear fusion power station comes on line. Aimed at the general public as well as those whose decisions directly affect energy policy, this book will be a valuable resource for informing future debates.

This book describes the manipulation of molecular properties, such as orientation, structure, and dynamics, of small molecules and molecular clusters isolated in cold inert matrices by using unprecedentedly strong external electrostatic fields. Manipulation of molecules with controllable external forces is a dream of chemists. Molecules are inherently quantum-mechanical systems, control of which potentially can lead to quantum technology, such as quantum sensing and computing. This book demonstrates a combination of the ice film nanocapacitor method and the matrix isolation technique enabled the application of intense external dc electric fields across the isolated molecules and molecular clusters. Changes in molecular states induced by fields were monitored by means of vibrational spectroscopy. Also, the book presents manipulations of the inversion tunneling dynamics of ammonia molecule and the dislocation of acidic proton in hydrogen chloride-water complex. The book shows that the vibrational spectroscopy with the aid of unprecedentedly strong dc electric field can provide rich information on the electrostatic behaviors of molecules and molecular clusters, which underlie the understanding of intermolecular processes and molecular manipulation.

This Open Access biography chronicles the life and achievements of the Norwegian engineer and physicist Rolf Wideroe. Readers who meet him in the pages of this book will wonder why he isn't better known. The first of Wideroe's many pioneering contributions in the field of accelerator physics was the betatron, the second, the linear accelerator, both summarized in a 27 page PhD. The betatron revolutionized the fields of cancer treatment through radiation therapy and also nondestructive testing; hospitals worldwide installed Wideroe's machine and today's modern radiation treatment equipment is based on his inventions. The most recent renaissance of the linac provides unprecedented x-ray intensities at Free Electron Laser (FEL) facilities in operation and construction worldwide. . Wideroe's story also includes a fair share of drama, particularly during World War II when both Germans and the Allies vied for his collaboration. Wideroe held leading positions in multinational industry groups and was one of the consultants for building the world's largest nuclear laboratory, CERN, in Switzerland. He gained over 200 patents, received several honorary doctorates and a number of international awards. The author, a professional writer and maker of TV documentaries, has gained access to hitherto restricted archives in several countries, which provided a wealth of new material and insights, in particular in relation to the war years. She tells here a gripping and illuminating story.

Optics has been part of scientific enquiry from its beginning and remains a key element of modern science. This book provides a concise treatment of physical optics starting with a brief summary of geometrical optics. Scalar diffraction theory is introduced to describe wave propagation and diffraction effects and provides the basis for Fourier methods for treating more complex diffraction problems. The rest of the book treats the physics underlying some important instruments for spectral analysis and optical metrology, reflection and transmission at dielectric surfaces and the polarization of light. This undergraduate-level text aims to aid understanding of optical applications in physical, engineering and life sciences or more advanced topics in modern optics.

Die beruhmte Vorlesung von Freeman Dyson - nun erstmals auf Deutsch. In den 1940er Jahren zeigte Freeman Dyson die Aquivalenz zwischen den beiden Formulierungen der QED - des Pfadintegralansatzes von Richard Feynman und der Variationsmethoden von Julian Schwinger - und bewies somit die Konsistenz der QED. Dieses Buch beinhaltet die wertvollen - nie zuvor auf Deutsch publizierten - Vorlesungen uber Quantenfeldtheorie, die Dyson an der Cornell Universitat 1951 gehalten hat.

Der Theoretiker Edwin Thompson Jaynes bemerkte dazu: "Fur eine Generation von Physikern waren diese Vorlesungen ein Gewinn: klarer und besser motiviert als Feynmans Vorlesungen, und schneller und kompakter als Schwingers." Zukunftige Leser werden diese Vorlesungen ebenfalls mit grossem Genuss lesen und von dem klaren Stil profitieren, der fur Dyson stets so charakteristisch gewesen ist.

Aus dem Inhaltsverzeichnis: 1 - Die Diracgleichung, 2 - Streuprobleme und die Born-Approximation, 3 - Die klassische und quantenmechanische Feldtheorie, 4 - Beispiele quantisierter Feldtheorien (Maxwellfeld, Diracelektronen), 5 - Streuprobleme freier Teilchen (Paar Annihilation, Moller-Streuung, Klein-Nishina-Formel), 6 - Allgemeine Theorie der Streuung (Feynman-Graphen, Infrarotkatastrophe), 7 - Streuung an einem statischen Potenzial und experimentelle Ergebnisse.

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Volume 2 of this three-part series presents the quantization of classical field theory using the path integral formalism. For this volume the target audience is students who wish to learn about relativistic quantum field theory applied to particle physics, however, it is still very accessible and useful for students of condensed matter. This volume begins with the introduction of the path integral formalism for non-relativistic quantum mechanics and then, using this as a basis, extends the formalism to quantum fields with an infinite number of degrees of freedom. Dr. Strickland then discusses how to quantize gauge fields using the Fadeev-Popov method and fermionic fields using Grassman algebra. He then presents the path integral formulation of quantum chromodynamics and its renormalization. Finally, he discusses the role played by topological solutions in non-abelian gauge theories.

This book brings together two broad themes that have generated a great deal of interest and excitement in the scientific and technical community in the last 100 years or so: quantum tunnelling and nonlinear dynamical systems. It applies these themes to nanostructured solid state heterostructures operating at room temperature to gain insight into novel photonic devices, systems and applications.

This book is a research monograph summarizing recent advances related to the molecular structure of water and ice, and it is based on the latest spectroscopic data available. A special focus is given to radio- and microwave frequency regions. Within the five interconnected chapters, the author reviews the electromagnetic waves interaction with water, ice, and moist substances, discussing the microscopic mechanisms behind the dielectric responses. Well-established classic views concerning the structure of water and ice are considered along with new approaches related to atomic and molecular dynamics. Particular attention is given to nanofluidics, atmospheric science, and electrochemistry. The mathematical apparatus, based on diverse approaches employed in condensed matter physics, is widely used and allows the reader to quantitatively describe the electrodynamic response of water and ice in both bulk and confined states. This book is intended for a wide audience covering physicists, electrochemists, geophysicists, engineers, biophysicists, and general scientists who work on the electromagnetic radiation interaction with water and moist substances.

Optics has been part of scientific enquiry from its beginning and remains a key element of modern science. This book provides a concise treatment of physical optics starting with a brief summary of geometrical optics. Scalar diffraction theory is introduced to describe wave propagation and diffraction effects and provides the basis for Fourier methods for treating more complex diffraction problems. The rest of the book treats the physics underlying some important instruments for spectral analysis and optical metrology, reflection and transmission at dielectric surfaces and the polarization of light. This undergraduate-level text aims to aid understanding of optical applications in physical, engineering and life sciences or more advanced topics in modern optics.