This comprehensive text is the definitive academic pain medicine resource for medical students, residents and fellows. Acting as both an introduction and continued reference for various levels of training, this guide provides practitioners with up-to-date academic standards. In order to comprehensively meet the need for such a contemporary text-treatment options, types of pain management, and variables affecting specific conditions are thoroughly examined across 48 chapters. Categories of pain conditions include orofacial, neuropathic, visceral, neck, acute, muscle and myofascial, chronic urogenital and pelvic, acute, and regional. Written by renowned experts in the field, each chapter is supplemented with high-quality color figures, tables and images that provide the reader with a fully immersive educational experience. Academic Pain Medicine: A Practical Guide to Rotations, Fellowship, and Beyond is an unprecedented contribution to the literature that addresses the wide-spread requisite for a practical guide to pain medicine within the academic environment.

This book addresses the pulmonary and non-pulmonary manifestations related to exposure to airborne hazards after the collapse of the World Trade Center. Leading experts consider both short and long term effects on survivors, first responders, and residents of surrounding areas and offer clinical practice guidelines for treatment. Respiratory complications are the most obvious manifestation, but the text additionally covers oncology, psychiatry, and other organ systems for both adults and children. Knowledge of the medical ramifications from the World Trade Center collapse has broad scientific applicability to occupational and environmental medicine, preventive medicine, and epidemiology. With the advent of bioterrorism since 9/11, understanding prevention, treatment, monitoring, and basic and clinical research aspects of particulate matter air pollution is relevant and critically important to being a medical provider. This book will prove useful to pulmonologists, primary care providers, epidemiologists, psychiatrists, occupational and environmental specialists, allergists, immunologists, toxicologists and public policy experts.

In the first book of its kind, Helen J. Power uses the history of the Liverpool School of Tropical Medicine to explore the development of tropical medicine in Britain in the twentieth century. The contributors also consider the social, political, and economic forces that shape medicine and its application in the context of imperialism, independence, and postcolonial history. The Liverpool School of Tropical Medicine provides a unique framework for exploring the changes which took place as medicine progressed from being a tool of empire, to a form of social welfare, and finally to a basic human right.

Percutaneous Penetration Enhancers in a mini-series format comprising five volumes, represents the most comprehensive reference on enhancement methods - both well established and recently introduced - in the field of dermal/transdermal drug delivery. In detail the broad range of both chemical and physical methods used to enhance the skin delivery of drugs is described. All aspects of drug delivery and measurement of penetration are covered, and the latest findings are provided on skin structure and function, mathematics in skin permeation, and modern analytical techniques adapted to assess and measure penetration. In offering a detailed description of the methods currently in use for penetration enhancement, this book will be of value for researchers, pharmaceutical scientists, practitioners, students and dermatological scientists or dermatologists .

This book offers up-to-date guidance in the diagnosis and management of the various complex complications that may be encountered during or after the placement of dental implants. The aim is to raise the awareness of clinicians regarding such complications and to equip them with the knowledge needed in order to deal with complications promptly and effectively. This in turn will assist in the avoidance of "complications of the initial complication", which is of critical importance in preventing more serious clinical and psychological problems for patients as well as medicolegal issues for clinicians. The range of complications covered in the book is very wide, encompassing medical, intraoperative, aesthetic, and infectious complications as well as medication-related osteonecrosis of the jaw, complications in the atrophic mandible, trigeminal nerve injuries, and more. Complex Dental Implant Complications is written by a team of leading experts and surgeons in the field. It will be a valuable aid for all clinicians who place dental implants.

Based on a conference on Oxidative Stress and Redox Regulation, held at the Pasteur Institute, Paris, this work examines fundamental, chemical, biological and medical studies of free radicals on different targets and the consequences of their reactivity. It covers the chemistry and biochemistry of free radicals, free radicals as second messengers that group the activation of transcription factors and enzymes, the importance of the antioxidant system in cell metabolism regulation, and the role of free radicals and antioxidants in disease management. The editors of this work are three of the most respected pioneers in the field. Dr. Montagnier is credited as the discoverer of HIV.

The Pocket Guide to Psychiatric Medications for Depression provides an indispensable guide to medications for the treatment of depression, including vital information on the approved indications, usual dosages, and maximum dosages for antidepressant medications. Derived from an appendix to The American Psychiatric Publishing Textbook of Psychopharmacology, Fifth Edition, this handy guide will serve as a valuable reference and essential starting point in psychopharmacology for depression for residents and experienced clinicians alike.

This atlas gathers the most frequent imaging findings concerning alterations that cause infertility in both males and in females. Also, it discusses how the images should be analyzed and described, to serve as a guide for the physicians who request and perform these imaging tests. Infertility is a highly prevalent condition - about 10% of couples are infertile with males and females equally affected. This book offers professionals dealing with infertility, including endocrinologists, gynecologists and urologists, a useful guide to the diagnostic imaging tests that are essential in treating these patients. The Atlas of Imaging in Infertility is a valuable resource for physicians from different specialties managing cases of infertility.

Electrical therapy of the heart has rapidly evolved over recent years with the development of the cardiac implantable defibrillator and the application of the cardiac resynchronization therapy to improve performance of the congestive failed heart. There is an impressive amount of literature produced to assess the efficacy and effectiveness of the electrical therapy. New technology is continuously introduced into the market for the treatment of electrical heart disease with optimized performance and implemented design, with approximately 600,000 new pacemakers implanted each year. Attention of the electrophysiology community has mainly focused on the biomedical aspects of electrical therapy, but the psychological, emotional, social and cognitive aspects of the implantable devices has been largely overlooked. Health-related quality of life (QoL) and, to a lesser extent, psychological disorders, i.e. anxiety and depression, have rarely been assessed as outcomes in clinical trials, and results are pointing towards the impact of the implantable devices on QoL and mental health not being direct but moderated and mediated by several biomedical as well as psychosocial variables. Furthermore, the cognitive effects of the implantable devices have rarely been assessed in empirical studies, although cognitive impairment is largely associated with the heart disorders that require implantation of an electrical device and cognitive benefits are strongly expected from the therapy. The aim of this book is to collect, appraise and condense the results of all empirical studies that have investigated, even marginally, the relationships between the implantable devices and any psychological, emotional, social and cognitive dimension. This book is a cornerstone for all involved in device utilization (physicians, nurses, technicians, industry representatives) that need to understand this topic.

A groundbreaking examination of addiction from a psychiatrist and public health doctor, offering practical, proven solutions for individuals, families, and communities dealing with substance use and abuse. Written with warmth, accessibility, and vast authority, The Addiction Solution is a practical guide through the world of drug use and abuse and addiction treatment. Here, Lloyd I. Sederer, MD, brings together scientific and clinical knowledge, policy suggestions, and case studies to describe our current drug crisis and establish a clear path forward to recovery and health. In a time when so many people are affected by the addiction epidemic, when 142 people die of overdoses every day in the United States, principally from opioids, Sederer's decades of wisdom and clinical experience are needed more than ever before. With a timely focus on opioids, Sederer takes us through the proven essentials of addiction treatment and explains why so many of our current policies, like the lingering remnants of the War on Drugs, fail to help drug users, their families, and their wider communities. He identifies a key insight, often overlooked in popular and professional writing about addiction and its treatment: namely, that people who use drugs do so to meet specific needs, and that drugs may be the best solution those people currently have. Writing with generosity and empathy about the many Americans who use illicit and prescribed substances, Sederer lays out specific, evidence-based, researched solutions to the prevention and problems of drug use, including exercise, medications, therapy, recovery programs, and community services. In this challenging time, The Addiction Solution provides practical help, comfort, and hope.

Propelling quantitative MRI techniques from bench to bedside, Quantitative MRI in Cancer presents a range of quantitative MRI methods for assessing tumor biology. It includes biophysical and theoretical explanations of the most relevant MRI techniques as well as examples of these techniques in cancer applications.

The introductory part of the book covers basic cancer biology, theoretical aspects of NMR/MRI physics, and the hardware required to form MR images. Forming the core of the book, the next three parts illustrate how to characterize tissue properties with endogenous and exogenous contrast mechanisms and discuss common image processing techniques relevant for cancer. The final part explores emerging areas of MR cancer characterization, including radiation therapy planning, cellular and molecular imaging, pH imaging, and hyperpolarized MR. Each of the post-introductory chapters describes the salient qualitative and quantitative aspects of the techniques before proceeding to preclinical and clinical applications. Each chapter also contains references for further study.

Leading the way toward more personalized medicine, this text brings together existing and emerging quantitative MRI techniques for assessing cancer. It provides a self-contained overview of the theoretical and experimental essentials and state of the art in cancer MRI.

This second edition of Ambulance Care Essentials offers a complete guide to the skills, knowledge and understanding required to work as a support worker or similar within the ambulance service. Covering fundamental elements of the role, the book combines theoretical aspects of communication, legal and ethical issues and safeguarding with more practical areas such as manual handling, medical emergencies and a range of clinical skills. It includes in-depth chapters on the primary areas of patient assessment as well as covering different patient populations across the lifecourse. Key features include: *Clearly illustrated, step-by-step instructions for range of practical skills and procedures including how to handle different types of trauma and cardiac arrest *Detailed anatomical diagrams to provide the reader with the necessary context to carry out the practical elements of their job more effectively *Evidence-based throughout and up-to-date with the latest guidance, policy and research *Specific chapters on each area of patient assessment and how to manage this effectively *Chapters dedicated to various patient populations such as obstetrics, paediatrics and older people *In-depth chapter on supporting senior clinicians and how best to assist the paramedic as a support worker This second edition has been brought up to-date with the latest national guidance. The book is appropriate for a Level 3 diploma course or similar that qualifies you to work as a support worker and covers learning objectives from a range of courses offered by ambulance services. It is an essential resource for anyone wanting to prepare themselves for a role within the ambulance service as well as those hoping to become a more effective member of an emergency ambulance crew.

Shell-Shock and Medical Culture in First World War Britain is a thought-provoking reassessment of medical responses to war-related psychological breakdown in the early twentieth century. Dr Loughran places shell-shock within the historical context of British psychological medicine to examine the intellectual resources doctors drew on as they struggled to make sense of nervous collapse. She reveals how medical approaches to shell-shock were formulated within an evolutionary framework which viewed mental breakdown as regression to a level characteristic of earlier stages of individual or racial development, but also ultimately resulted in greater understanding and acceptance of psychoanalytic approaches to human mind and behaviour. Through its demonstration of the crucial importance of concepts of mind-body relations, gender, willpower and instinct to the diagnosis of shell-shock, this book locates the disorder within a series of debates on human identity dating back to the Darwinian revolution and extending far beyond the medical sphere.

This practical guide offers concise coverage of the scientific and pharmaceutical aspects of protein delivery from controlled release microparticulate systems-emphasizing protein stability during encapsulation and release.

This book discusses the latest findings on the physiological and pathological functions of transient receptor potential canonical/classical (TRPC) proteins in the brain. In addition to reviewing the functions of TRPCs in brain development and neuron transmission, it mainly covers the potential roles of TRPCs in brain disorders. TRPC proteins belong to the TRP channel superfamily, which has around 30 members. Just like TRP channels, TRPCs are non-selectively permeable to cations, with a selectivity of calcium over sodium that varies among different members. The TRPC subfamily consists of six members, grouped on the basis of the similarities in gene sequence and protein structure in mammalians. What sets TRPCs apart from other subfamilies in TRPs is that their activation, stimulated by a membrane receptor-phospholipid C (PLC) cascade, contributes to the slow and sustained elevation of intracellular free calcium. Calcium ions, one of the most important types of second messengers, mediate a variety of physiological functions in the brain, including progenitor cell proliferation, dendritic formation, synaptic transmission and neuronal survival. All TRPCs except TRPC7 have been found in various regions of the brain, including the cerebrum, cerebellum, forebrain and hippocampus. This book provides students and investigators with comprehensive information on the regulation, function and potential of TRPCs and brain diseases in order to attract more attention to this field.

This book presents fifty clinical cases in neuro-ophthalmology, some of which are common and some of which are rare. Each case is presented as a diagnostic and management challenge as found in clinical practice. High quality clinical photographs and images bring the cases to life alongside the diagnostic process and management decisions of an experienced specialist. A short summary of important aspects of the pathogenesis and treatment of each disease finishes each case. Neuro-Ophthalmology: Illustrated Case Studies entertains and instructs the reader and is ideal reading for doctors in training in this area, as well as general consultant neurologists and ophthalmologists.

Created to meet the unique needs of addiction professionals, this practical resource offers suggestions for effectively using activities in groups. It addresses common issues counselors frequently need to discuss with clients and provides an array of "tried and true" techniques and exercises designed to help clients develop interpersonal relationship skills and the individual awareness needed to make responsible choices. The accompanying CD- ROM contains all the exercises allowing therapists to customize them to fit their needs.

Edited by Sudhir Diwan, a former Director of Pain Medicine fellowship program at Ivy League Weill Cornell Medical College, and Timothy R. Deer, an internationally renowned expert in neuromodulation and minimally invasive spinal procedures, this atlas covers advanced procedures that normal residency and fellowship programs may not cover. It consolidates information pain fellows usually amass by traveling throughout the country to various specialized weekend courses. Advanced Procedures for Interventional Pain Management: A Step-by-Step Atlas is for physicians that know the fundamentals of pain medicine and want to push their knowledge further. Through easy-to-digest bullet points, extensive diagrams, hundreds of figures, and expanded legends beneath each illustration, this compendium covers techniques such as fluoroscopic guidance and radiation safety, endoscopic transforaminal discectomy, endoscopic direct-percutaneous discectomy, transforaminal myelogram, percutaneous facet fusion, percutaneous sacroplasty, vertebral augmentations, percutaneous tumor ablation, percutaneous spinal fusion, minimally invasive spinal decompression (MILD), Interspinous Spacer Placement and advanced neuroaugmentation techniques like high frequency stimulation and DRG stimulation. This book also has a dedicated section on Regenerative Medicine with chapters on platelet rich plasma, stem cell therapy, and intradiscal regenerative therapy. Each chapter has a strict chapter format that includes the indications and contraindications for each procedure, a list of equipment and drugs, a step-by-step illustration-focused how-to, a list of possible post-procedural complications, and bullet-pointed clinical pearls and pitfalls. Within each chapter the authors will also cover the variations of each procedure due to different equipment. This book is ideal for pain medicine fellows, spine surgeons, and interventional pain physicians who want access to the best minds and specialized procedures in a single package.

In our society, bullying is commonly seen as a normal, inescapable part of growing up that children and adolescents must simply endure. In Bullying, Suicide, and Homicide, Butch Losey challenges this viewpoint, arguing that bullying is not a part of childhood development, but rather an aberrant behavior that, for the victim, can lead to adverse decisions, such as suicide and homicide. He provides a detailed understanding of the relationship between bullying, suicide, and homicide and an assessment and response strategy that can be utilized by mental health professionals who work with children and adolescents. This strategy involves a three stage ecological approach: screening to identify warning signs for bullying, depression, suicide, and violence by means of the Bullying Lethality Identification System (BLIS), developed by Losey and a colleague; assessing the risks of suicide and threats of violence using specially tailored forms and tools; and mediating to identify appropriate interventions. All of the associated tools and forms that the author has created are included as appendices and on the accompanying CD. Losey's sensitive and compassionate treatment of this important subject will inform and motivate mental health professionals in their work with victims of bullying.

In this clinically rich and deeply personal book, Chris Jaenicke demonstrates that the therapeutic process involves change in both the patient and the analyst, and that therapy will not have a lasting effect until the inevitability and depth of the analyst's involvement in the intersubjective field is better understood. In other words, in order to change, we must allow ourselves to be changed. This can happen within the sessions themselves, as one grasps the influence of and decenters from one's own subjectivity, with cumulative effects over the course of the treatment. Thus the process, limitations, and cure of psychotherapy are cocreated, without displacing the asymmetrical nature of roles and responsibility. Essentially, beyond the theories and techniques, it is the specificity of our subjectivity as it interacts with the patient's subjectivity which plays the central role in the therapeutic process.

Children and adolescents with attention-deficit/hyperactivity disorder (ADHD) frequently experience co-occurring problems with aggression, mood swings, tics, anxiety, or depression. Organized around detailed case presentations, this highly informative book helps the clinician make sound decisions when assessing and treating the full range of ADHD comorbidities. Experienced child psychiatrist Steven Pliszka offers straightforward guidance on how to avoid common diagnostic errors, develop an individualized medication regimen, minimize health risks and side effects, collaborate successfully with parents, and tailor psychosocial treatments to each family's needs. A reproducible structured interview facilitates sorting out symptoms and distinguishing between different comorbid disorders.

Acute heart failure is a potentially life threatening situation where correct, rapid therapy can save lives. Information from the latest research and studies has been used to update this text to bring the latest understanding of the pathophysiology together with a practical guide to diagnosis and management using an evidenced based approach. Since the first edition of Acute Heart Failure, this research has brought to light three important issues to be integrated into a second edition. First, the so-called "vascular heart failure" has been identified as a common and decisive mechanism provoking acute heart failure due to the coupling and interaction between the heart (right and left heart) and the large vessel systems (aorta and pulmonary artery). Second, the interaction and cross-talk between heart and kidneys, the so-called 'cardiorenal syndrome' has been identified as another feature of acute heart failure syndromes. Third, we have new knowledge and updated points of views about the development of pulmonary hypertension in patients suffering from heart failure, the group 2 of the classification system of pulmonary hypertension. These are all covered in this second edition. This revision to a seminal text is a valuable addition to any practitioner who treats patients with acute heart failure and wants a deeper understanding of the condition.

A practical and colourful introductory guide, Endodontology at a Glance covers all the essential topics (diagnosis, endodontic therapy, pain management and outcome of treatment) as well as the recent developments that comprise the field of endodontology. Written by experts in the field, the book explores the causes and sequelae of endodontic disease and offers suggestions for taking an effective patient history. New addition to the At a Glance series covering a core area of dentistry Review style makes for the ideal revision companion Includes access to a companion website with MCQs for self-assessment and downloadable images for use in teaching

Summarizes various approaches to schizophrenia and points to their weaknesses and strengths. To gain a better understanding of the condition, the text considers factors including deprivation, cultural influences and brain function. It also challenges over-reliance on 19th century phenomenology.