Progress in Medicinal Chemistry, Volume 60 provides a review of eclectic developments in medicinal chemistry. Each chapter is written by an international board of authors who cover topics including Venoms in Drug Discovery, Designing Protacs as a Drugs, Automated synthesis and enabling tools for Medicinal Chemistry, Use of Molecular Docking Computational Tools in Drug Discovery, and An industrial perspective on co-crystals: screening, identification and development of the less utilized solid form in drug discovery and development.

Advances in Pharmacology, Volume 91, the latest release in this well-received series, presents the latest information in the field, with this update including chapters on Modulation of inflammation and immune response by the stress-activated transcription factor Nrf2, Therapeutic modulation of macrophage phenotype to treat acute and chronic liver diseases, Immodulation by cannabinoids, The use of nanomaterials to target immunity, Next generation in cancer immunotherapy, checkpoint inhibitors, Vaccines as a therapy for food allergy, Role of inflammation/immune system in depression, Therapeutic targeting of tumor-associated macrophages, Mast cells, and more.

Humane Alternatives to the Psychiatric Model is the second Volume of the Ethics International Press Critical Psychology and Critical Psychiatry Series. Understanding the current systems of psychology and psychiatry is profoundly important. So is exploring alternatives. The Critical Psychology Critical Psychology and Critical Psychiatry Series presents solicited chapters from international experts on a wide variety of underexplored subjects. This is a series for mental health researchers, teachers, and practitioners, for parents and interested lay readers, and for anyone trying to make sense of anxiety, depression, and other emotional difficulties. Humane Alternatives to the Psychiatric Modelpresents a variety of alternative models and approaches that are available in addition to, or instead of, the current predominant psychiatric "mental disorder" model. Humane Alternatives to the Psychiatric Modelprovides more than twenty solicited chapters from experts worldwide, among them Peter Kinderman, former president of the British Psychological Society, and other respected cultural commentators and mental health experts.

Advances in Parasitology, Volume 112, the latest release in this ongoing series, includes medical studies of parasites of major influence, along with reviews of more traditional areas, such as zoology, taxonomy and life history. Chapters in this update include Taking the strain out of onchocerciasis: a reanalysis of blindness and transmission data does not support the existence of a savanna blinding strain of onchocerciasis in West Africa, Enterocytozoon bieneusi of animals, Taenia solium taeniasis/cysticercosis, Genomic analysis reveals predominant clonality and progressive evolution at all evolutionary scales in eukaryotic pathogens, HTLV-I and Strongyloides: the worm lurking beneath, and more.

Celebrating Fifty Years of Picador Books If a man has lost a leg or an eye, he knows he has lost a leg or an eye; but if he has lost a self - himself - he cannot know it, because he is no longer there to know it. In this extraordinary book, Dr. Oliver Sacks recounts the stories of patients struggling to adapt to often bizarre worlds of neurological disorder. Here are people who can no longer recognize everyday objects or those they love; who are stricken with violent tics or shout involuntary obscenities, and yet are gifted with unusually acute artistic or mathematical talents. If sometimes beyond our surface comprehension, these brilliant tales illuminate what it means to be human. A provocative exploration of the mysteries of the human mind, The Man Who Mistook His Wife for a Hat is a million-copy bestseller by the twentieth century's greatest neurologist. Part of the Picador Collection, a series showcasing the best of modern literature.

Computer-Aided Oral and Maxillofacial Surgery: Developments, Applications, and Future Perspectives is an ideal resource for biomedical engineers and computer scientists, clinicians and clinical researchers looking for an understanding on the latest technologies applied to oral and maxillofacial surgery. In facial surgery, computer-aided decisions supplement all kind of treatment stages, from a diagnosis to follow-up examinations. This book gives an in-depth overview of state-of-the-art technologies, such as deep learning, augmented reality, virtual reality and intraoperative navigation, as applied to oral and maxillofacial surgery. It covers applications of facial surgery that are at the interface between medicine and computer science. Examples include the automatic segmentation and registration of anatomical and pathological structures, like tumors in the facial area, intraoperative navigation in facial surgery and its recent developments and challenges for treatments like zygomatic implant placement.

Annual Report on Medicinal Chemistry series, highlights new advances in the field with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.