Environmental Carcinogenesis, Volume 96 in the Advances in Pharmacology series, reports on work done with carcinogenic metals and the mechanisms of their carcinogenicity, including Arsenic and Chromate. Chapters in this release include Breast cancer carcinogenesis by organophosphate pesticides, Polyadenylation of Canonical histone H3.1 in Carcinogenesis, Epigenomic reprogramming in iAs-mediated carcinogenesis, MicroRNAs and epigenetic regulation in metal-induced angiogenesis and carcinogenesis, Environmental epigenetics and new mechanistic markers of chemical exposure, Arsenic carcinogenesis by inhibition of DNA repair, Genetic and environmental reprogramming of the sarcoma epigenome, Mechanism of chromate carcinogenesis by chromatin alterations, and more. Other chapters cover Arsenic carcinogenesis and microRNAs, Epigenetic mechanism of Cr(VI)-induced cell malignant transformation and tumorigenesis, The dark side of NRF2 in arsenic carcinogenesis, and Chemical mechanisms of DNA damage by carcinogenic chromium(VI).

Biomedical Applications of Green Composites reviews the use of green composite materials in drug delivery, with a focus on capsules, resins and ceramides in biomedical fields. Chapters present green composites of polymeric origin and targeted delivery of drugs into various parts of the human body. Other sections in the book cover topics related to the applications of green composites in areas such as antimicrobial agents, pathogen control, surgical applications, dentistry and cancer therapy.

Hybridisation in Parasites: Disease Evolution by Saltation, Volume 119 in the Advances in Parasitology: Disease Evolution by Saltation, the latest release in this ongoing series, includes medical studies of parasites of major influence, along with reviews of more traditional areas, such as zoology, taxonomy and life history.

Have you, a friend or family member been living with undiagnosed autism?

For every visibly Autistic person you meet, there are countless 'masked' people who pass as neurotypical. They don't fit the stereotypical mould of Autism and are often forced by necessity to mask who they are, spending their entire lives trying to hide their Autistic traits. In particular, there is evidence that Autism remains significantly undiagnosed in women, people of colour, trans and gender non-conforming people, many of whom are only now starting to recognise those traits later in life.

Blending cutting-edge research, personal insights and practical exercises for self-expression, Dr Devon Price examines the phenomenon of 'masking', making a passionate argument for radical authenticity and non-conformity. A powerful call for change, Unmasking Autism gifts its readers with the tools to uncover their true selves and build a new society - one where everyone can thrive on their own terms.

Hygienic Design of Food Factories, Second Edition includes updates on existing chapters, along with new sections on cold storage, the control of air in food refrigeration facilities, and prevention of contamination when building during production and regulations in Asian countries (other than Japan). Sections cover the implications of hygiene and construction regulation in various countries on food factory design, describe site selection, factory layout and the associated issue of airflow, and address the hygienic design of essential parts of a food factory, including walls, ceilings, floors, selected utility and process support systems, entry and exit points, storage areas, and more. With its distinguished editors and international team of contributors, this book continues to be an essential reference for managers of food factories, food plant engineers, and all those with an academic research interest in the field.

What role does coercion play in psychiatric treatment? Does it increase or decrease the chances for successful outcome?

"Forced Into Treatment "discusses various aspects of coercion ranging from the role of coercion in initiation psychiatric treatment to its effect on treatment process and outcome. The book demonstrated that a patient who is appropriately forced into treatment can more from initial defiance, through reluctant compliance, to a successful therapeutic alliance and a successful outcome.

In addition, "Forced Into Treatment" addresses - the role of coercion, power, and authority in socializing children - the use of coercive social pressure as a motivation to seek help - the effects of court-ordered treatment for people who have refused psychiatric help - the historical and legal aspects regarding coercive treatment

This book focuses on oral health promotion and the impact of systemic disease in the development of oral disease, as well as how to introduce, apply, and communicate prevention to a patient with a defined risk profile. Prevention in Clinical Oral Health Care integrates preventive approaches into clinical practice, and is a valuable tool for all health care professionals to integrate oral health prevention as a component of their overall preventive message to the patient. Discusses risk-based approaches to prevent problems such as caries, periodontal disease, and oral cancer. Topics are written at a level that can be understood by both practicing dental health team members and by dental hygiene and dental students so strategies can be applied to better understand the patient's risk for oral disease and how to prevent future disease. Identifies the barriers, oral health care needs, and preventive strategies for special populations such as children, the elderly, and the physically or mentally disabled. Explores the development of a culturally sensitive dental practice and strategies to make the dental environment more welcoming to individuals with different cultural backgrounds. Discusses how to gather patient information, the synthesis of the patient's data, and the application of the information collected in order to evaluate the patient's risk for disease.

While the genesis of the Certified Child Life Specialists (CCLS) is in the healthcare setting, the theory and practice of child life has been successfully applied to environments outside of the healthcare field. The interest and pursuit of child life roles in non-healthcare settings have increasingly become of interest to students and professionals; however, further study is required to understand the various challenges and opportunities. The Role of Child Life Specialists in Community Settings serves as an innovative guide for those interested in pursuing child life in diverse settings with the education and credentials received through their child life certification and addresses issues the field currently faces related to saturation of the field, burn out, and diversity, equity, and inclusion. The book also serves as a catalyst to push the profession as a whole beyond its current healthcare boundaries. Covering topics such as grief, addiction, disaster relief, and family wellbeing, this major reference work is ideal for psychologists, medical professionals, nurses, policymakers, government officials, researchers, scholars, academicians, practitioners, instructors, and students.

We are often judged by how we look, and the first thing people notice is a smile. Dr. Zaibak, honored by the Consumers Research Council of America for the last five years as one of America's top dentists, discusses important issues relating to dental health and improving your teeth, your smile, and your self-esteem. Dr. Zaibak has been featured on national and local media outlets including ABC, WGN Superstation, Fox, and Univision, and has served as an expert commentator for the "Chicago Sun-Times." This all-inclusive book unveils the hidden truth about Lumineers porcelain veneers, Invisalign metal-free braces, teeth whitening, bonding, implants, crowns, bridges, Snap-On Smiles, and gum lifts. The health of your teeth and mouth affect the well-being of your entire body. "The Hidden Truth Behind Beautiful Smiles" reveals the secrets to enhancing your teeth to produce an exquisite, engaging smile that will positively transform your self-image and your life.

Authored by the originator of the standard nomenclature for this spectrum of disorders, Congenital Heart Disease: A Clinical, Pathological, Embryological, and Segmental Analysis discusses the history, anatomic features, and physiologic consequences of CHD-in one authoritative resource. The Van Praagh approach to the segmental classification of CHD, developed and implemented by Dr. Richard Van Praagh in the 1960s at Boston Children's Hospital, remains widely used today, facilitating communication among radiologists, cardiologists, surgeons, and pediatricians who are involved in the diagnosis, characterization, and management of this disease. This unique atlas offers complete coverage of the ubiquitous Van Praagh "language" of CHD, including the signs, symptoms, and clinical manifestations of malpositioned, malformed, or absent cardiovascular chambers, vessels, and valves using traditional as well as state-of-the-art technology. Based upon the systematic, widely accepted Van Praagh system of three-part notation used to succinctly describe the visceroatrial situs, the orientation of the ventricular loop, and the position and relation of the great vessels. Demonstrates how the Van Praagh approach facilitates interpreting and reporting findings through cardiac imaging with CT, MR, and ultrasonography, including fetal cardiac imaging. Presents the pathologic anatomy that pediatric and adult cardiologists, radiologists, and echocardiographers need to understand in order to make accurate diagnoses in complex congenital heart disease; as well as the pathologic anatomy that interventionists, pediatric cardiac surgeons, and adult congenital heart surgeons need to know in order to manage their patients successfully. Features more than 550 high-quality images to help you visualize and recognize malformations. Shares the knowledge and expertise of a world-renowned authority on congenital heart disease-a master teacher and the originator of the Van Praagh segmental classification system. Explores the synergy between the various disciplines who manage patient care, including surgeons, radiologists, cardiologists, pathologists, and pediatricians. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

Anti-Aging Pharmacology provides an overview of current research aimed at the pharmacological modulation of aging, including a discussion of the growing number of novel drug classes with promising anti-aging potential. The aging process is the main risk factor for all chronic diseases affecting the elderly. With lifespans extending across the globe, these chronic diseases are placing a larger burden on individuals and health care systems. Therefore, slowing down the aging rate could be more effective in delaying aging-associated chronic disorders than combating them one by one, which is the conventional approach in a current disease-based pharmacological paradigm. This book contains the work of the world's leading researchers in the field, including sections on the conceptual and methodological background of anti-aging pharmacology, the basic classes of anti-aging drugs, phytochemicals, outcomes of anti-aging developments and future directions. This book will be of interest to a wide audience, ranging from pharmacologists, medicinal chemists and academic researchers in gerontology, biomedical sciences and those in medical practice.

Phytochemistry, Computational Tools and Databases in Drug Discovery presents the state-of-the-art in computational methods and techniques for drug discovery studies from medicinal plants. Various tools and databases for virtual screening and characterization of plant bioactive compounds and their subsequent predictions on biological targets for the discovery of new drugs against specific diseases are presented, along with computational tools for the prediction of the toxic effects of phytochemicals on living systems. The book also provides in-depth insight on the applications of these computational tools as well as the databases that describe the interactions of phytochemicals with diseases along with predictions for druggable bioactive compounds. Useful for drug developers, medicinal chemists, toxicologists, phytochemists, plant biochemists and analytical chemists, this book clearly presents the various computational techniques, tools and databases for phytochemical research.

Virtual Screening and Drug Docking, Volume 59 in the Annual Reports on Medicinal Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Can docking scoring functions guarantee success in virtual screening?, No dance, no partner! A tale of flexibility in docking and virtual screening, Handling Imbalance Data in Virtual Screening, Rational computational approaches to predict novel drug candidates against leishmaniasis, Virtual screening against Mtb DNA gyrase: Applications and success stories, Using Filters in Virtual Screening: A Brief Guide to Minimize Errors and Maximize Efficiency, and more. Additional chapters in the new release include Machine Learning and Deep Learning Strategies for Virtual Screening, Applications of the Virtual Screening to find the novel HIV-1 therapeutic agents, and Large-scale screening of small molecules with docking strategies and its impact on drug discovery.