Medical Image Analysis presents practical knowledge on medical image computing and analysis as written by top educators and experts. This text is a modern, practical, self-contained reference that conveys a mix of fundamental methodological concepts within different medical domains. Sections cover core representations and properties of digital images and image enhancement techniques, advanced image computing methods (including segmentation, registration, motion and shape analysis), machine learning, how medical image computing (MIC) is used in clinical and medical research, and how to identify alternative strategies and employ software tools to solve typical problems in MIC.

Phytopharmaceuticals and Herbal Drugs: Prospects and Safety Issues in the Delivery of Natural Products explores the delivery aspects of plant-based drugs, providing insights into formulation constraints associated with plant-based drugs, the development of novel delivery systems based on polymers or lipids, and how combining natural products with technological advancements in drug delivery is making large strides. Some of the best-selling drugs for the treatment of diseases like cancer, ulcers and malaria are either natural products or their derivatives, all of which are covered in this comprehensive resource. This book will be useful to researchers working in plant-derived medicines and the development of their delivery systems, including sections on their derivatives and analogs that represent over 50% of all drugs in clinical use. Active ingredients originated from plant resources generally exhibit compromised desired effects limited by issues such as stability, solubility, molecular size, bioavailability and toxicity.

Why is it that well-prepared, talented, hardworking, and intelligent performers find their performance and self-esteem undermined by the fear of memory slips, technique failures, and public humiliation? In Managing Stage Fright: A Guide for Musicians and Music Teachers, author Julie Jaffee Nagel unravels these mysteries, taking the reader on an intensive backstage tour of the anxious performer's emotions to explain why stage fright happens and what performers can do to increase their comfort in the glare of the spotlight. Examining the topic from her interdisciplinary educational, theoretical, clinical, and personal perspectives, Nagel uses the music teacher/student relationship as a model for understanding the performance anxiety that affects musicians and non-musicians alike. Shedding new light on how the performer's emotional life is connected to every other facet of their life, Managing Stage Fright encourages a deeper understanding of anxiety when performing. The guide offers strategies for achieving performance confidence, emphasizing the relevance of mental health in teaching and performing. Through the practices of self-awareness outlined in the book, Nagel demonstrates that it is possible and desirable for teachers to assist students in developing the coping skills and attitudes that will allow them to not feel overwhelmed and powerless when they experience strong anxiety. Each chapter contains insights that help teachers recognize the symptoms-obvious, subtle, and puzzling-of the emotional grip of stage fright, while offering practical guidelines that empower teachers to empower their students. The psychological concepts offered, when added to pedagogical techniques, are invaluable in music performance and in a variety of life situations since, after all, music lessons are life lessons.

Emergency management of acute poisoning is an emergency medicine short course that equips emergency personnel to assess acutely poisoned patients rapidly and accurately. This title is also valuable to nursing staff, senior pre-hospital health professionals and general practitioners. It provides a framework within which emergency personnel can safely work without being swamped by unnecessary details. The more commonly encountered cases of poisoning are discussed with guidelines for appropriate 'syndrome based' management of unknown toxicity while further investigations are being conducted.

From Current to Future Trends in Pharmaceutical Technology explores the current trends of this field and creates a multi-aspect framework for the reader. The book covers topics on pharmaceutics, pharmaceutical engineering, pre-formulation protocols, techniques, innovative excipients, bio-printing techniques, scale-up based on formulas on-a-chip, and regulatory aspects based on new scientific achievements. Modified dosage forms, new aspects on the compatibility of drug excipients interactions, and drug release by various dosage forms are included. Physical pharmacy (physical and biological stability of dosage forms), innovative excipients, patents on innovative formulations and regulatory issues related to the approval process of medicines are also discussed. The book is a valuable resource for a wide audience of academics, industrial researchers and professionals working in this field as the development of efficient and safe medicines is critical to future needs.

Dihydropyrimidinones as Potent Anticancer Agents gives readers a unique update on scientific knowledge, accomplishments and recent advances in the medicinal chemistry of dihydropyrimidinones in cancer treatment. Dihydropyrimidinones are known to be active scaffold and have been reported to show some exceptional results with regards to malignancies. With ever increasing knowledge and information about synthesis, pharmacology and other aspects of dihydropyrimidinones, there is need to document such information in one place. Since the field of medicinal chemistry is dynamic, with new emerging trends, it provides readily available updated information on chemistry and pharmacology aspects of dihydropyrimidinones in cancer. This book covers everything about dihydropyrimidinones from synthesis, derivatives, mode of action and potential therapeutic targets. It will also provide insights about the clinical trials and way forward in cancer research of dihydropyrimidinones.

Updated with findings from the latest research, this contributed work on the psychology of women covers global initiatives, theories, and practical applications in various settings. It also addresses best practices of feminist methodologies and teaching psychology of women courses. As societal gender standards continue to shift and the capabilities, strengths, and needs of women become more widely acknowledged and prioritized-even as myths regarding women's leadership, health, and work behavior persist-it becomes increasingly important to understand the psychology of women. This third edition of Psychology of Women provides updated and expanded coverage of this highly significant and relevant subject through diverse perspectives of internationally known scholars in their disciplines, offering synopses of recent research and examinations of key theoretical issues, global initiatives, and practical applications in the workplace, therapy, and educational settings. A resource ideally suited to students in women's studies and the psychology of women as well as for use as a handbook for scholars, faculty members, and specialists in fields relating to the psychology of women, the book covers specific topics such as women in middle age, women's career development and challenges in integrating work and family roles, and the ongoing problem of violence against women. This latest edition also includes best practices of feminist methodologies and information regarding teaching psychology of women courses, and it emphasizes placing value on all women, including women of color, women with disabilities, and lesbian, bisexual, and transgender women. Presents the latest empirical research findings, global initiatives, and theories on women's psychology Dispels myths about women's career development, mental illness, women leaders, and women's achievements Challenges traditional views of women's mental health and physical health by presenting objective data in these areas Offers recommendations for feminist therapy and physical health issues

Over one-third of our lives is dedicated to the workplace. Accordingly, occupational psychiatrists strive to understand the psychological impact of the workplace on an employee's emotional health. They also study the effects of a patient's psychiatric disorder on this environment.

"Introduction to Occupational Psychiatry" presents the importance of the workplace in psychiatric treatment. In addition, the book explores the numerous opportunities for employment in occupational psychiatry and defines the necessary steps to obtain one of these positions.

Medicinal Chemistry of Anticancer Drugs, Third Edition provides an updated resource for students and researchers from the point-of-view of medicinal chemistry and drug design, focusing on the mechanism of action of antitumor drugs from the molecular level, and on the relationship between chemical structure and chemical and biochemical reactivity of antitumor agents. The new edition includes updated sections on the hot topic of cancer immunotherapy, cancer polypharmacology, multitargeted cancer therapy, medicinal chemistry of cancer diagnosis, theragnostic anticancer agents, and pre-mRNA processing in cancer. Although many books are available that deal with clinical aspects of cancer chemotherapy, this book provides a unique and valuable perspective from the point-of-view of medicinal chemistry and drug design. It will be useful to undergraduate and postgraduate students of medicinal chemistry, pharmacology, biological chemistry, pharmacy and other health sciences. Researchers and practitioners will find a comprehensive treatment of the topic and a large number of references, reviews and primary literature.

Environmental Carcinogenesis, Volume 96 in the Advances in Pharmacology series, reports on work done with carcinogenic metals and the mechanisms of their carcinogenicity, including Arsenic and Chromate. Chapters in this release include Breast cancer carcinogenesis by organophosphate pesticides, Polyadenylation of Canonical histone H3.1 in Carcinogenesis, Epigenomic reprogramming in iAs-mediated carcinogenesis, MicroRNAs and epigenetic regulation in metal-induced angiogenesis and carcinogenesis, Environmental epigenetics and new mechanistic markers of chemical exposure, Arsenic carcinogenesis by inhibition of DNA repair, Genetic and environmental reprogramming of the sarcoma epigenome, Mechanism of chromate carcinogenesis by chromatin alterations, and more. Other chapters cover Arsenic carcinogenesis and microRNAs, Epigenetic mechanism of Cr(VI)-induced cell malignant transformation and tumorigenesis, The dark side of NRF2 in arsenic carcinogenesis, and Chemical mechanisms of DNA damage by carcinogenic chromium(VI).

Advances in the Study of Behavior, Volume 55 highlights new advances in the field, with this new volume presenting interesting chapters on Playing to the crowd: using Drosophila to dissect mechanisms underlying plastic male strategies in sperm competition games, Social breeding and its challenges: A case study on village weaverbirds, Inbreeding depression and social interactions, and Sleeping beauties? Copulatory quiescence in arachnid females.

Mathematics for Physical Chemistry, Fifth Edition includes exercises that enable readers to test their understanding and put theory into practice. Chapters are constructed around a sequence of mathematical topics, progressing gradually into more advanced material, before discussing key mathematical skills, including the analysis of experimental data and-new to this edition-complex variables. Includes additional new content on Mathematica and its advanced applications. Drawing on the experience of its expert authors, this book is the ideal supplementary text for practicing chemists and students wanting to sharpen their mathematics skills and understanding of key mathematical concepts for applications across physical chemistry.

Biomedical Applications of Green Composites reviews the use of green composite materials in drug delivery, with a focus on capsules, resins and ceramides in biomedical fields. Chapters present green composites of polymeric origin and targeted delivery of drugs into various parts of the human body. Other sections in the book cover topics related to the applications of green composites in areas such as antimicrobial agents, pathogen control, surgical applications, dentistry and cancer therapy.

Hybridisation in Parasites: Disease Evolution by Saltation, Volume 119 in the Advances in Parasitology: Disease Evolution by Saltation, the latest release in this ongoing series, includes medical studies of parasites of major influence, along with reviews of more traditional areas, such as zoology, taxonomy and life history.

Hygienic Design of Food Factories, Second Edition includes updates on existing chapters, along with new sections on cold storage, the control of air in food refrigeration facilities, and prevention of contamination when building during production and regulations in Asian countries (other than Japan). Sections cover the implications of hygiene and construction regulation in various countries on food factory design, describe site selection, factory layout and the associated issue of airflow, and address the hygienic design of essential parts of a food factory, including walls, ceilings, floors, selected utility and process support systems, entry and exit points, storage areas, and more. With its distinguished editors and international team of contributors, this book continues to be an essential reference for managers of food factories, food plant engineers, and all those with an academic research interest in the field.

Imaging Neuroinflammation provides an overview of the molecular and cellular basis of inflammation and its effects on neuroanatomy, reviews state-of-the-art imaging tools available to measure neuroinflammation, and describes the application of those tools to both preclinical animal disease models and human disease.This book is an authoritative reference on imaging neuroinflammation, MRI, neuroinflammation, MR Spectroscopy of inflammation, Iron imaging in inflammation, and more.

Medicines for Cancer: Mechanism of Action and Clinical Pharmacology of Chemo, Hormonal, Targeted, and Immunotherapies is a comprehensive volume covering most of the known anti-cancer therapeutics. Cancer is the second leading cause of death worldwide, with its various forms resulting in nearly one out of every six mortalities each year. This book describes all US FDA-approved drugs (up to 2021), such as small molecules, peptides, monoclonal antibodies, whole antibodies, gene therapy, antibody-drug conjugates, and cell therapy, and immunotherapies are considered, and information about their generic and brand names, medical uses, details dosage, mechanisms of actions, pharmacokinetics, and side effects. Chemical structures of small molecules, small peptides, antibody-drug conjugates are also provided. Medicines for Cancer: Mechanism of Action and Clinical Pharmacology of Chemo, Hormonal, Targeted, and Immunotherapies is ideal for medicinal chemists, oncologists, and pharmacologists, this book will be indispensable for professional researchers, whether they are working in the clinic or the pharmaceutical industry.

Advances in Parasitology, Volume 120, the latest release in this ongoing series, includes medical studies of parasites of major influence, along with reviews of more traditional areas, such as zoology, taxonomy and life history.

Written for all therapists who want to understand this groundbreaking theory as it might actually show up in their day-to-day practice, this book offers a comprehensive approach to polyvagal-informed intervention. Worksheets and experiential exercises designed to map and shape autonomic response provide therapists with a road map for bringing polyvagal theory into their clinical practice.

What role does coercion play in psychiatric treatment? Does it increase or decrease the chances for successful outcome?

"Forced Into Treatment "discusses various aspects of coercion ranging from the role of coercion in initiation psychiatric treatment to its effect on treatment process and outcome. The book demonstrated that a patient who is appropriately forced into treatment can more from initial defiance, through reluctant compliance, to a successful therapeutic alliance and a successful outcome.

In addition, "Forced Into Treatment" addresses - the role of coercion, power, and authority in socializing children - the use of coercive social pressure as a motivation to seek help - the effects of court-ordered treatment for people who have refused psychiatric help - the historical and legal aspects regarding coercive treatment