Although textbooks on the physics of condensed matter consider non-covalent interactions in detail, their application for analysis of protein properties is often poorly presented or omitted. On the other hand, books on biochemistry, molecular modeling or molecular simulation introduce these interactions in the context of the corresponding topic, which sometimes results in superficial explanations of their nature. This book succeeds in uniting comprehensive considerations of non-covalent interactions with the specificity of their application in protein sciences.This second edition includes new chapters on intrinsically disordered proteins, microcalorimetry of proteins, cold denaturation, thermodynamic stability and thermal adaptability of proteins. The ideal aid for students of physics or chemistry, with interests in biology and biophysics, the book can also be useful for students of biology, biochemistry, or biomedicine who want to extend their knowledge of how protein properties are described at the molecular level.

This short textbook covers roughly 13 weeks of lectures on advanced statistical mechanics at the graduate level. It starts with an elementary introduction to the theory of ensembles from classical mechanics, and then goes on to quantum statistical mechanics with density matrix. These topics are covered concisely and briefly. The advanced topics cover the mean-field theory for phase transitions, the Ising models and their exact solutions, and critical phenomena and their scaling theory. The mean-field theories are discussed thoroughly with several different perspectives - focusing on a single degree, or using Feynman-Jensen-Bogoliubov inequality, cavity method, or Landau theory. The renormalization group theory is mentioned only briefly. As examples of computational and numerical approach, there is a chapter on Monte Carlo method including the cluster algorithms. The second half of the book studies nonequilibrium statistical mechanics, which includes the Brownian motion, the Langevin and Fokker-Planck equations, Boltzmann equation, linear response theory, and the Jarzynski equality. The book ends with a brief discussion of irreversibility. The topics are supplemented by problem sets (with partial answers) and supplementary readings up to the current research, such as heat transport with a Fokker-Planck approach.

Visual Astronomy introduces the basics of observational astronomy, a fundamentally limitless opportunity to learn about the universe with your unaided eyes or with tools such as binoculars, telescopes, or cameras.

Our understanding of subatomic particles developed over many years, although a clear picture of the different particles, their interactions and their inter-relationships only emerged in the latter part of the twentieth century. The first ""subatomic particles"" to be investigated were those which exhibit readily observable macroscopic behavior, specifically these are the photon, which we observe as light and the electron, which is manifested as electricity. The true nature of these particles, however, only became clear within the last century or so. The development of the Standard Model provided clarification of the way in which various particles, specifically the hadrons, relate to one another and the way in which their properties are determined by their structure. The final piece, perhaps, of the final model, that is the means by which some particles acquire mass, has just recently been clarified with the observation of the Higgs boson. Since the 1970s it has been known that the measured solar neutrino flux was inconsistent with the flux predicted by solar models. The existence of neutrinos with mass would allow for neutrino flavor oscillations and would provide an explanation for this discrepancy. Only in the past few years, has there been clear experimental evidence that neutrinos have mass. The description of particle structure on the basis of the Standard Model, along with recent discoveries concerning neutrino properties, provides us with a comprehensive picture of the properties of subatomic particles. Part I of the present book provides an overview of the Standard Model of particle physics including an overview of the discovery and properties of the Higgs boson. Part II of the book summarizes the important investigations into the physics of neutrinos and provides an overview of the interpretation of these studies.

This introduction to quantum field theory (QFT) is written by a physical chemist for physical chemists, chemical physicists, and other non-physicists with knowledge of quantum theory but who want to explore ways in which they might use the power of QFT in their investigations. This book starts where many graduate courses in quantum theory that are offered to chemistry students leave off and first develops some of the necessary tools, such as Fock algebra, which is applied to solving the quantum oscillator problem. Then it is used to develop the theory of coherent states, time-dependent perturbation theory, and the treatment of bosons and fermions. With this background, the QFT of a perfect gas is derived and a connection to thermodynamics is demonstrated. Application to imperfect gases provides a new approach to modelling gas-liquid phase transitions. The book concludes with photons and their interaction with molecular ensembles, and brings us to full circle by deriving the blackbody radiation law, which started it all. The power of the QFT methodology and the breadth of its applications should fascinate the reader as it has the author.

Problems with the conceptual foundations of quantum mechanics date back to attempts by Max Born, Niels Bohr, Werner Heisenberg, as well as many others in the 1920s to continue to employ the classical concept of a particle in the context of the quantum world. The experimental observations at the time and the assumption that the classical concept of a particle was to be preserved have led to an enormous literature on the foundations of quantum mechanics and a great deal of confusion then and now among non-physicists and students in any field that involves quantum theory. It is the historical approach to the teaching of quantum mechanics that is at the root of the problem.Spacetime is the arena within which quantum mechanical phenomena take place. For this reason, several Appendices are devoted to the nature of spacetime as well as to topics that can help us understand it such as vacuum fluctuations, the Unruh effect and Hawking radiation.Because of the success of quantum mechanical calculations, those who wish to understand the foundations of the theory are often given the apocryphal advice, 'just ignore the issue and calculate'. It is hoped that this book will help dispel some of the dismay, frustration, and confusion among those who refuse to take to heart this admonition.

The interface between Physics and Mathematics has been increasingly spotlighted by the discovery of algebraic, geometric, and topological properties in physical phenomena. A profound example is the relation of noncommutative geometry, arising from algebras in mathematics, to the so-called quantum groups in the physical viewpoint. Two apparently unrelated puzzles - the solubility of some lattice models in statistical mechanics and the integrability of differential equations for special problems - are encoded in a common algebraic condition, the Yang-Baxter equation. This backdrop motivates the subject of this book, which reveals Knot Theory as a highly intuitive formalism that is intimately connected to Quantum Field Theory and serves as a basis to String Theory.This book presents a didactic approach to knots, braids, links, and polynomial invariants which are powerful and developing techniques that rise up to the challenges in String Theory, Quantum Field Theory, and Statistical Physics. It introduces readers to Knot Theory and its applications through formal and practical (computational) methods, with clarity, completeness, and minimal demand of requisite knowledge on the subject. As a result, advanced undergraduates in Physics, Mathematics, or Engineering, will find this book an excellent and self-contained guide to the algebraic, geometric, and topological tools for advanced studies in theoretical physics and mathematics.

The interface between Physics and Mathematics has been increasingly spotlighted by the discovery of algebraic, geometric, and topological properties in physical phenomena. A profound example is the relation of noncommutative geometry, arising from algebras in mathematics, to the so-called quantum groups in the physical viewpoint. Two apparently unrelated puzzles - the solubility of some lattice models in statistical mechanics and the integrability of differential equations for special problems - are encoded in a common algebraic condition, the Yang-Baxter equation. This backdrop motivates the subject of this book, which reveals Knot Theory as a highly intuitive formalism that is intimately connected to Quantum Field Theory and serves as a basis to String Theory.This book presents a didactic approach to knots, braids, links, and polynomial invariants which are powerful and developing techniques that rise up to the challenges in String Theory, Quantum Field Theory, and Statistical Physics. It introduces readers to Knot Theory and its applications through formal and practical (computational) methods, with clarity, completeness, and minimal demand of requisite knowledge on the subject. As a result, advanced undergraduates in Physics, Mathematics, or Engineering, will find this book an excellent and self-contained guide to the algebraic, geometric, and topological tools for advanced studies in theoretical physics and mathematics.

All living matter is comprised of cells, small compartments isolated from the environment by a cell membrane and filled with concentrated solutions of various organic and inorganic compounds. Some organisms are single-cell, where all life functions are performed by that cell. Others have groups of cells, or organs, specializing in one particular function. The survival of the entire organism depends on all of its cells and organs fulfilling their roles. While the cells are studied by different sciences, they are seen differently by biologists, chemists, or physicists. Biologists concentrate their attention on cell structure and function. What the cells consists of? Where are its organelles? What function each organelle fulfils? From a chemists' point of view, a cell is a complex chemical reaction chamber where various molecules are synthesized or degraded. The main question is how these, sometimes very complicated chains of reactions are controlled. Finally, from a physics standpoint, some of the fundamental questions are about the physical movement of all these molecules between organelles within the cell, their exchange with the extracellular medium, as well as electrical phenomena resulting from such transport. The aim of this book is to look into the basic physical phenomena occurring in cells. These physical transport processes facilitate chemical reactions in the cell and various electrical effects, and that in turn leads to biological functions necessary for the cell to satisfy its role in the mother organism. Ultimately, the goals of every cell are to stay alive and to fulfill its function as a part of a larger organ or organism. The first volume of this book is an inventory of physical transport processes occurring in cells while this second volume provides a closer look at how complex biological and physiological cell phenomena result from these very basic physical processes.

2013 Winner (Gold Medal), Classical Studies/Philosophy, Independent Publisher Book Awards -- 2013 Winner, Spirituality: General, International Book Awards -- 2013 Winner, Science, National Indie Excellence Awards -- 2013 Finalist, Science: General, International Book Awards -- 2013 Finalist, Best New Non-Fiction, International Book Awards -- 2013 Finalist, Best Cover Design: Non-Fiction, International Book Awards -- 2013 Finalist, Philosophy, National Indie Excellence Awards -- The Eternal Law takes the reader on a fascinating journey through some of the most profound questions related to our understanding of modern science. What does it mean to say that there is an eternal mathematical law underpinning all of physical reality? How must we expand our narrow conception of science to include not only logic but also intuition, consciousness, and the pursuit of beauty, symmetry, simplicity, and unity? Is truth objective, or is it nothing more than a whimsical projection of opinions? Why were many of the key founders of modern science inevitably drawn to ancient Greek philosophy? Spencer's extraordinary clarity helps to restore a sane vision of reality, while deepening our appreciation of what Einstein called 'the mysterious'.

Exam Board: Edexcel Level: AS/A-level Subject: Physics First Teaching: September 2015 First Exam: June 2016 Endorsed by Edexcel Help students to build and develop the essential knowledge and skills needed, provide practical assessment guidance and plenty of support for the new mathematical requirements with this Edexcel Year 1 Student Book. - Supports practical assessment with Practical Skill summaries throughout - Provides support for all 16 required practicals with detailed explanations, data and exam style questions for students to answer - Builds understanding and knowledge with a variety of questions to engage and challenge students throughout the course: prior knowledge, worked examples, Test Yourself and Exam Practice Questions - Acts as an aid for the mathematical requirements of the course with worked examples of calculations and a dedicated 'Maths in Physics' chapter - Develop understanding and enable self- and peer-assessment with free online access to 'Test yourself' answers. Edexcel A level Physics Student Book 1 includes AS level.

Exam Board: OCR Level: A level Subject: Science / Physics First teaching: September 2015 First exams: June 2017 An ActiveBook is included with every Student Book, giving your students easy online access to the content in the Student Book. They can make it their own with notes, highlights and links to their wider reading. Perfect for supporting work and revision activities. Student Book 1 supports a standalone AS course and provides the first year of a two-year A level course; Student Books 1 and 2 together support the full A level course. A cumulative approach to learning constantly builds on what has previously been taught. The chapter openers highlight prior learning requirements and link to future learning. The required maths skills are highlighted at the start of each chapter providing opportunities for students to check understanding and remedy gaps. Bigger spreads require students to read real-life material that's relevant to the course and use knowledge in new contexts. Accompanying questions require students to analyse how scientists write, think critically and consider issues. Preparing for your exams sections highlight the key differences between preparing for an AS and full A level exam. Practice question spreads provide opportunities for students to regularly check their understanding using questions written in the style of the new exams from day one.

This book is for senior undergraduates, graduate students and researchers interested in understanding the physical and chemical interactions of organic semiconductors on emergent two-dimensional (2D) materials. Molecular electronics has come of age, and there is now a pressing need to understand molecule-2D material heterointerfaces at the nanoscale. The purpose of this book is to present a coherent coverage of these heterointerfaces for next generation molecular memories, switches, bio-sensors and magnetic quantum devices. In this interdisciplinary collection, advances in the application of scanning probe and high-resolution synchrotron techniques are illustrated.

Biochemistry of Lipids, Lipoproteins and Membranes, Seventh Edition serves as a comprehensive, general reference book for scientists and students studying lipids, lipoproteins and membranes. Here, across 19 chapters, leaders in the field summarize fundamental concepts, recent research developments, data analysis, and implications for human disease and intervention. Topics discussed include lipid biology in both prokaryotes and eukaryotes, fatty acid synthesis, desaturation and elongation, and pathways leading to synthesis of complex phospholipids, sphingolipids and their structural variants. Chapters also examine how bioactive lipids are involved in cell signaling, with an emphasis on disease implications and pathological consequences. As the field advances, each chapter in this new edition has been fully revised to address emerging topics, with all-new coverage of lipid droplets and their role as regulatory organelles for energy homeostasis, as well as their relationship to obesity, liver disease and diabetes. Evolving research in fatty acid handling and storage in eukaryotes is also discussed in-depth, with new sections addressing fatty acid uptake, activation and lipolysis.

A glass is disordered material like a viscous liquid and behaves mechanically like a solid. A glass is normally formed by supercooling the viscous liquid fast enough to avoid crystallization, and the liquid-glass transition occurs in diverse manners depending on the materials, their history, and the supercooling processes, among other factors. The glass transition in colloids, molecular systems, and polymers is studied worldwide. This book presents a unified theory of the liquid-glass transition on the basis of the two band model from statistical quantum field theory associated with the temperature Green's function method. It is firmly original in its approach and will be of interest to researchers and students specializing in the glass transition across the physical sciences.