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This book focuses on the systems biomechanics of bone remodeling that provide a multiscale platform for bone adaptation, spanning the cellular, tissue, and organ levels. The mathematical model explained in each section provides concrete examples of in silico approaches for bone adaptation. It will be immensely useful for readers interested in bone morphology and metabolism and will serve as an effective bridge connecting mechanics, cellular and molecular biology, and medical sciences. These in silico approaches towards exploring the mechanisms by which the functioning of dynamic living systems is established and maintained have potential for facilitating the efforts of graduate students and young researchers pioneering new frontiers of biomechanics.
Packed with vivid illustrations and a wealth of hands-on applications, best-selling FUNDAMENTALS OF ANATOMY AND PHYSIOLOGY, 4E is written specifically for learners in a one-semester introductory A&P course in the allied health field who have little or no previous knowledge of anatomy and physiology. Known for its clear approach to teaching, the text is widely praised for its ability to break A&P down into very simple, easy to understand language. Content is organized according to body systems, and focuses on the body working together to promote homeostasis. Improving both the quality and quantity of text illustrations, the Fourth Edition's new art program brings text concepts to life with new figures throughout. Designed specifically for the needs of health care programs, the all-new Learning Lab's interactive simulation program helps learners maximize their success.
This traditional lab manual for the A&P course examines every structure and function of the human body. In addition to a large variety of illustrations, the manual features dissection of the cat, numerous physiological experiments, an emphasis on the study of anatomy through histology, lists of appropriate terms accompanying art, numerous photomicrographs and specimen photos, phonetic pronunciation and derivation of terms, diagrams of lab equipment, lab report questions and report templates, and three appendices. An instructor's guide is available and provides detailed information for instructors about needed materials, suggestions, and answers to questions.
Five leaders in the field of mammalian preimplantation embryo development provide their own perspectives on key molecular and cellular processes that mediate lineage formation during the first week of life. The first cell-fate decision involves the formation of the pluripotent inner cell mass (ICM) and extraembryonic trophectoderm (TE). The second cell-fate choice encompasses the transformation of ICM into extraembryonic primitive endoderm (PE) and pluripotent epiblast. The processes, which occur during the period of preimplantation development, serve as the foundation for subsequent developmental events such as implantation, placentation, and gastrulation. The mechanisms that regulate them are complex and involve many different factors operating spatially and temporally over several days to modulate embryonic chromatin structure, impose cellular polarity, and direct distinct gene expression programs in the first cell lineages.
Offering a concise, illustrated summary of biochemistry and its relevance to clinical medicine, Medical Biochemistry at a Glance is intended for students of medicine and the biomedical sciences such as nutrition, biochemistry, sports science, medical laboratory sciences, physiotherapy, pharmacy, physiology, pharmacology, genetics and veterinary science. It also provides a succinct review and reference for medical practitioners and biomedical scientists who need to quickly refresh their knowledge of medical biochemistry. The book is designed as a revision guide for students preparing for examinations and contains topics that have been identified as 'high-yield' facts for the United States Medical Licensing Examination (USMLE), Step 1. This third edition: * Has been thoroughly revised and updated and is now in full colour throughout * Is written by the author of the hugely successful Metabolism at a Glance (ISBN 9781405107167) * Features updated and improved clinical correlates * Expands its coverage with a new section on Molecular Biology * Includes a brand new companion website of self-assessment questions and answers at www.ataglanceseries.com/medicalbiochemistry
From women's medicine and the writings of Christine de Pizan to the lives of market and tradeswomen and the idealization of virginity, gender and social status dictated all aspects of women's lives during the middle ages. A cross-disciplinary resource, Women and Gender in Medieval Europe examines the daily reality of medieval women from all walks of life in Europe between 450 CE and 1500 CE, i.e., from the fall of the Roman Empire to the discovery of the Americas. Moving beyond biographies of famous noble women of the middles ages, the scope of this important reference work is vast and provides a comprehensive understanding of medieval women's lives and experiences. Masculinity in the middle ages is also addressed to provide important context for understanding women's roles. Entries that range from 250 words to 4,500 words in length thoroughly explore topics in the following areas: * Art and Architecture * Countries, Realms, and Regions * Daily Life * Documentary Sources * Economics * Education and Learning * Gender and Sexuality * Historiography * Law * Literature * Medicine and Science * Music and Dance * Persons * Philosophy * Politics * Political Figures * Religion and Theology * Religious Figures * Social Organization and Status Written by renowned international scholars, Women and Gender in Medieval Europe is the latest in the Routledge Encyclopedias of the Middle Ages. Easily accessible in an A-to-Z format, students, researchers, and scholars will find this outstanding reference work to be an invaluable resource on women in Medieval Europe.
Published by the American College of Sports Medicine, this authoritative manual teaches health fitness professionals and students how to appropriately conduct fitness assessment testing. The focus on assessment makes this content critical for those studying to enter the fitness and rehabilitation fields, as well as those already working who need to align their practice to industry standards. This new edition has been fully updated to reflect key changes from the tenth edition of the ACSM's Guidelines for Exercise Testing and Prescription . The goal of this Fifth Edition of ACSM's Health-Related Physical Fitness Manual is to provide a comprehensive overview of why and how to perform assessments of the five health-related components of physical fitness, namely body composition, muscular strength, muscular endurance, flexibility, and cardiorespiratory fitness.
This book discusses the importance of oxidative stress, related biomarkers, and its diagnostic methods including bio-analytical and advanced detection systems. Oxidative stress is associated with diminished capacity of a biological system to overcome the overproduction of reactive oxygen species. Since oxidative stress has been suggested as a causative factor in many diseases, its prevention is vital, and there is an urgent need for oxidative stress monitoring using in vitro and in vivo models. Interdisciplinary approaches have lead to the development of various oxidative stress monitoring models for real-world clinical and biomedical applications. The development of such methods requires a broad understanding of biology, chemistry, molecular biology, immunology and microbiology. As such, the book is a valuable resource for students, researchers and clinicians interested in the fundamental as well as applied aspects of oxidative stress associated diseases.
In Everything Moves, Susan Lowell de Solorzano shares her understanding of biotensegrity as developed over years of direct study with the concept's originator, Stephen M. Levin. Biotensegrity becomes accessible experientially, yet without shying away from the complexities involved. The material presented is suitable for coaches and movement teachers new to biotensegrity as well as those with more advanced levels of understanding. Whether their focus is performance, sports, Alexander Technique, Feldenkrais, yoga, Pilates, martial arts, or dance, any arena in which bodies move can be informed by Everything Moves.
Close your eyes and ask yourself, 'what do I feel?' You might feel thirsty or tired. You might feel healthy and well or perhaps a little under the weather. Maybe you can feel that you are standing or that you are leaning over. You may also feel the world around you - the shape and texture of an apple in your hand, the feel of a chair you're sitting on. All these feelings have something in common, say psychologists and neuroscientists. They are all mental events, things that happen in the mind. But what if this is all wrong? What if it's not just the mind, but also the body itself that feels? And not merely physical sensations, but other feelings that seem to have nothing to do with bodies. Things like 'emotions' and 'intuitions' - joy or rage, anxiety or optimism, or the feeling of being hard done by or misunderstood? Drawing on the latest research and a range of classic and contemporary thought, How You Feel shows you that your brain and your body are two parts of a single system that creates your mind and mental life. You will discover that you don't have feelings, thoughts and emotions inside your body, you have them with your body. There can be no mind without the body. Psychology is no longer about the brain, or about 'mind and body', it is about the whole that is you.
This book guides readers through a wide spectrum of clinical presentations in patients with arterial hypertension and different degrees of renal impairment, ranging from asymptomatic urine abnormalities to end stage renal disease. On the basis of six case studies, the author reviews and discusses current guidelines and recommendations aimed at optimizing the diagnostic and therapeutic approach both to renal and cardiovascular risk in commonly encountered real-world clinical scenarios including challenging cases of diabetic kidney disease, ischemic nephropathy and resistant hypertension. It also explores anti-hypertensive drug combinations, including single or multiple RAAS-I, lipid lowering and antiplatelet drugs, as well as the appropriate use of glucose lowering drugs in the context of chronic kidney disease. This handy and practical book provides physicians in the area of general and internal medicine, as well as specialists in the cardiovascular, metabolic and renal fields valuable insights into optimal therapeutic targets for blood pressure and glucose control in renal patients.
Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. PreTest is the closest you can get to seeing the USMLE Step 1 before you take it 500 USMLE-type questions and answers! "This edition of PreTest is full of extremely high-yield information in a presentation that is logical and effective. The questions and explanations are invaluable, and the HY tables and figures make it easy to review important material efficiently." -- Gustaf Van Acker III, Fourth Year MD/PhD Candidate, University of Kansas School of Medicine "This book was an excellent refresher for anyone looking to review information for either their final course exam or for the USMLE Step 1." -- Ben Chidester, Second Year Medical Student, Eastern Virginia Medical School Great for course review and the USMLE Step 1, Anatomy, Histology, & Cell Biology: PreTest asks the right questions so you'll know the right answers. You'll find 500 clinical-vignette style questions and answers along with complete explanations of correct and incorrect answers. The content has been reviewed by students who recently passed their exams, so you know you are studying the most relevant and up-to-date material possible. No other study guide targets what you really need to know in order to pass like PreTest! Content that covers all the must-know topics: High-Yield Facts,Embryology: Early and General,Cell Biology: Membranes,Cell Biology: Cytoplasm,Cell Biology: Intracellular Trafficking,Cell Biology: Nucleus,Epithelium,Connective Tissues,Specialized Connective Tissues: Bones and Cartilage,Muscle and Cell Motility,Nervous System,Cardiovascular System, Blood and Bone Marrow,Lymphoid System and Cellular Immunology,Respiratory System,Integumentary System,Gastrointestinal Tract and Glands,Endocrine Glands,Reproductive System,Urinary System,Eye and Ear,Head and Neck Thorax,Abdomen,Pelvis,Extremities and Spine
Published by the American College of Sports Medicine, this Fifth Edition of ACSM's Resources for the Personal Trainer is the critical content for those seeking to gain ACSM's Certified Personal Trainer certification, and those currently practicing. This title is now fully aligned to the tenth edition of ACSM's Guidelines for Exercise Testing and Prescription, and includes the new pre-participation guidelines, which will be critical for those in the personal trainer field. This title continues to recognize the Personal Trainer as a professional in the continuum of creating healthy lifestyles and provides the Personal Trainer with both the tools and scientific evidence to build safe and effective exercise programs for a variety of clients. ACSM's Resources for the Personal Trainer is the official preparation book for the ACSM Certified Personal TrainerSM examination. Divided into six distinctly different parts, ranging from an introduction to the profession of personal training to how to run a personal training business, ACSM's Resources for the Personal Trainer provides coverage of anatomy, exercise physiology, biomechanics, behavior modification, and nutrition as well as assessment of strength and flexibility and the development of resistance and cardiorespiratory training programs. The science- and evidence-based approach allows the Personal Trainer to transfer knowledge to their clients effectively.
Discover how the individual parts of the human body function and work together: in this accessible and fascinating examination, you can navigate through the body from head to toe, looking at each individual area. As you read The Human Body, you will find out incredible facts, such as: * The average person produces about 0.75-1.1ml tears (lacrimal fluid) every day * A marathon runner achieves 40 percent greater cardiac output than an untrained person * Sneezes travel at 160km/h (100 mph) Clear, jargon-free text describes the function of individual parts of the body, from the skull and brain to all the major organs, bone structures and nervous systems, giving a comprehensive insight into the parts of the body we take for granted. All artworks are annotated to make every element clear. If you need to know about the human body and how it works, this is the book for you.
Milady's Student Reference for Anatomy and Physiology has been revised and expanded. This all-new edition includes more comprehensive coverage of the various body systems as well as brief descriptions of each system to increase understanding of the system's function. This must-have reference for the beauty and wellness student includes cross sections and multiple views of eleven main body systems. This is the perfect addition to any cosmetology, barbering, nail technology, esthetics or massage therapy student's study materials.
In every sport, there are athletes who represent true technical excellence. Their movement seems effortless and efficient: they create and control forces in the most effective way. Functional force management, the foundation for effective sporting movement and injury resistance, results from the integration of stability, mobility, coordination and balance. These elements combine to prevent the physical restrictions, imbalances and inefficient muscle recruitment patterns which can block athletes from meeting their movement goals. The right muscles firing at the right time and in the right sequence can enable athletes to achieve their full physical potential. Full of colour photographs and images to illustrate the techniques and theories involved, Stability, Sport, and Performance Movement introduces functional stability principles as they apply to sporting movement. A comprehensive chapter on movement testing is followed with four chapters of integrated exercise techniques, which clearly demonstrate form and progression from early activation through to higher-level neuromuscular drills.Programmes and clinical examples help the reader to appreciate the application of this approach across a variety of sports. It is an approach that has been used with international-level athletes in disciplines as diverse as swimming, badminton, gymnastics, karate, cycling, weight lifting, basketball, athletics, snow sports, football, golf, equestrian sports, and tennis. Effective movement starts with great foundations, and these are applicable and relevant across all age groups and ability levels, from beginners through to veterans.
This book, combining and updating two previous editions, is a unique source of information on the diagnosis, treatment, and follow-up of metabolic diseases. The clinical and laboratory data characteristic of rare metabolic conditions can be bewildering for both clinicians and laboratory personnel. Reference laboratory data are scattered, and clinical descriptions may be obscure. The "Physician s Guide "documents the features of more than five hundred conditions, grouped according to type of disorder, organ system affected (e.g. liver, kidney, etc) or phenotype (e.g. neurological, hepatic, etc). Relevant clinical findings are provided and pathological values for diagnostic metabolites highlighted. Guidance on appropriate biochemical genetic testing is provided. Established experimental therapeutic protocols are described, with recommendations on follow-up and monitoring. The authors are acknowledged experts, and the book will be a valuable desk reference for all who deal with inherited metabolic diseases."
EXERCISE PHYSIOLOGY, International Edition presents the fundamental concepts of exercise physiology. You will learn the immediate and long-term effects of exercise on physiological systems in the context of the most recent research, including molecular and genetics studies. The book focuses on issues like obesity, diabetes, and metabolic syndrome, and is designed to address the global pandemic of sedentary diseases in all age groups. The examples are integrated throughout and link the principles of exercise physiology to strategies that you can use to apply the science in real-life client situations.
Molecular Exercise Physiology: An Introduction is the first student-friendly textbook to be published on this key topic in contemporary sport and exercise science. It introduces sport and exercise genetics and the molecular mechanisms by which exercise causes adaptation. The text is linked to real life sport and exercise science situations such as what makes people good at distance running?, what DNA sequence variations code for a high muscle mass? or by what mechanisms does exercise improve type2 diabetes?
The book includes a full range of useful features, such as summaries, definitions of key terms, guides to further reading, review questions, personal comments by molecular exercise pioneers (Booth, Bouchard) and leading research in the field, as well as descriptions of research methods. A companion website offers interactive and downloadable resources for both student and lecturers.
Structured around central themes in sport and exercise science, such as nutrition, endurance training, resistance training, exercise & chronic disease and ageing, this book is the perfect foundation around which to build a complete upper-level undergraduate or postgraduate course on molecular exercise physiology."
Metabolism, behaviour, sleep, mood swings, the immune system, fighting, fleeing, puberty and sex: these are just a few of the things our bodies control with hormones. Armed with a healthy dose of wit and curiosity, medical journalist Randi Hutter Epstein takes us on a journey through the unusual history of these potent chemicals from a basement filled with jarred nineteenth-century brains to a twenty-first-century hormone clinic in Los Angeles. Brimming with fascinating anecdotes, illuminating new medical research and humorous details, Aroused introduces the leading scientists who made life-changing discoveries about the hormone imbalances that ail us, as well as the charlatans who used those discoveries to peddle false remedies.
This book underlines the importance of reciprocal interactions between probiotics and humans in terms of stress induction, epigenetic control of cellular responses, oxidative status, bioactive molecules biosynthesis, moonlighting proteins secretion, endogenous toxins neutralization, and several other biological functions. It explores how these responses can affect metabolism and metabolic-related disorders, gutbrain axis balance, mood, inflammatory, allergic and anti-infective reactions, cancer, and ageing. The book explores how probiotics create a dynamic and "fluid" network of signals able to control the balance between healthy and altered human status.
Part of the Oxford Textbooks in Clinical Neurology series, the Oxford Textbook of Clinical Neurophysiology includes sections that provide a summary of the basic science underlying neurophysiological techniques, a description of the techniques themselves, including normal values, and a description of the use of the techniques in clinical situations. Much of diagnostic neurophysiology is essentially pattern recognition which is illustrated throughout the text using audio and video examples. Divided into four key sections, this book begins with the scientific basis of clinical neurophysiology (Section 1) before exploring specific techniques including Electromyography, Intracranial EEG recordings, and Magnetoencephalography (Section 2). The final two sections explore clinical aspects of both the peripheral nervous system (Section 3) and the central nervous system (Section 4).
Focused on stem cell applications, this book bridges the fields of biomaterials, offering new insights into constructing and regenerating tissues and organs. Its unique feature is linking diseases of the human body to current thinking on how to deal with them in the context of current concepts and technologies by means of an in-depth focus on biomaterials. The book assembles recent advances and covers a range of topics related to stem cell biology, biomaterials and technological approaches such as bioreactors written by top researchers in the field. Stem cells of both embryonic and adult origin are discussed with applications ranging, but not limited to, nerve regeneration, liver, pancreas, skin, trachea, cartilage and bone repair and cardiovascular therapy. Developments in the field reflecting the design and construction of the human body and its principal anatomy are discussed from a materials point of view. The book will be a valuable tool for biomaterial scientists, tissue engineers, clinicians as well as stem cell biologists involved in basic research and applications of adult and embryonic stem cells. It will also be a source of reference for students in biotechnology, biomedical engineering, biology, biochemistry, materials sciences, pharmaceuticals, and veterinary and human medicine.
Stem cells potentially offer a novel therapeutic platform to treat bone disease. They also help the scientist understand the molecular and cellular aetiology of bone disorders. Gaining knowledge on the nature and application of stem cell sciences is a prerequisite for understanding their potential in treating or preventing bone disorders. Stem Cells and Bone Tissue is designed to address these areas in three sections: Introductory Text and Sources of Stem Cells for Skeletal Tissue Cellular and Molecular Aspects Conditions, Applications, Treatments and Repairs Coverage includes general aspects of stems cells, sources of stems cells, isolation and purification, applications in regeneration, nanoscale topography, myostatin (GDF-8) signalling, c-Jun, Lnk, cell-derived Factor 1/CXCR4, chromatin remodelling, osteoporosis, osteoarthritis, hypophosphatasia, osteopetrosis, osteogenesis, and many other areas of merit too numerous to mention.
This new study guide is a companion to the bestselling textbook Fundamentals of Anatomy and Physiology for Nursing and Healthcare Students, and is designed to help and support you with this subject area, by testing and consolidating your knowledge of anatomy and physiology. Jam-packed with tips, hints, activities and exercises, this workbook will guide you through the core areas of anatomy and physiology, and provide you with loads of help with your studies. Designed to support all styles of learning, Fundamentals of Anatomy and Physiology Workbook provides you with a wide range of activities including: * Clear illustrations for tracing, copying, shading and colouring in * Blank diagrams for labelling * Multiple choice questions * Fill in the gap exercises * Learning tips and hints * Crosswords * Word searches Also available: Fundamentals of Anatomy and Physiology for Nursing and Healthcare Students 2nd edition the bestselling textbook upon which this study guide is based.
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