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Books > Medicine > Pre-clinical medicine: basic sciences > Physiology

Hydrogen Sulfide in Redox Biology Part B, Volume 555 (Hardcover): Enrique Cadenas, Lester Packer Hydrogen Sulfide in Redox Biology Part B, Volume 555 (Hardcover)
Enrique Cadenas, Lester Packer
R4,310 Discovery Miles 43 100 Ships in 10 - 15 working days

These new volumes of Methods in Enzymology (554 and 555) on Hydrogen Sulfide Signaling continue the legacy established by previous volumes on another gasotransmitter, nitric oxide (Methods in Enzymology volumes 359, 396, 440, and 441), with quality chapters authored by leaders in the field of hydrogen sulfide research. These volumes of Methods in Enzymology were designed as a compendium for hydrogen sulfide detection methods, the pharmacological activity of hydrogen sulfide donors, the redox biochemistry of hydrogen sulfide and its metabolism in mammalian tissues, the mechanisms inherent in hydrogen sulfide cell signaling and transcriptional pathways, and cell signaling in specific systems, such as cardiovascular and nervous system as well as its function in inflammatory responses. Two chapters are also devoted to hydrogen sulfide in plants and a newcomer, molecular hydrogen, its function as a novel antioxidant.

Hydrogen Sulfide in Redox Biology Part A, Volume 554 (Hardcover): Enrique Cadenas, Lester Packer Hydrogen Sulfide in Redox Biology Part A, Volume 554 (Hardcover)
Enrique Cadenas, Lester Packer
R4,303 Discovery Miles 43 030 Ships in 10 - 15 working days

These new volumes of Methods in Enzymology (554 and 555) on Hydrogen Sulfide Signaling continue the legacy established by previous volumes on another gasotransmitter, nitric oxide (Methods in Enzymology volumes 359, 396, 440, and 441), with quality chapters authored by leaders in the field of hydrogen sulfide research. These volumes of Methods in Enzymology were designed as a compendium for hydrogen sulfide detection methods, the pharmacological activity of hydrogen sulfide donors, the redox biochemistry of hydrogen sulfide and its metabolism in mammalian tissues, the mechanisms inherent in hydrogen sulfide cell signaling and transcriptional pathways, and cell signaling in specific systems, such as cardiovascular and nervous system as well as its function in inflammatory responses. Two chapters are also devoted to hydrogen sulfide in plants and a newcomer, molecular hydrogen, its function as a novel antioxidant.

Cellular Adhesion in Development and Disease, Volume 112 (Hardcover): Alpha Yap Cellular Adhesion in Development and Disease, Volume 112 (Hardcover)
Alpha Yap
R4,541 Discovery Miles 45 410 Ships in 10 - 15 working days

Cell adhesion is a fundamental determinant of embryonic development and organogenesis. Cellular Adhesion in Development and Disease, volume 112 in Current Topics in Developmental Biology, comprehensively surveys current developments in understanding how adhesion systems affect organismal development. Topics covered include nectins, nectin-like molecules, and afadin in development; cadherin adhesion, signaling, and morphogenesis; endothelial cell junctions; epidermal development and barrier formation; and more.

Inflammation and Obesity - A New and Novel Approach to Manage Obesity and its Consequences (Paperback): Raman Mehrzad Inflammation and Obesity - A New and Novel Approach to Manage Obesity and its Consequences (Paperback)
Raman Mehrzad
R3,237 Discovery Miles 32 370 Ships in 10 - 15 working days

Inflammation and Obesity: A New and Novel Approach to Manage Obesity and its Consequences is a comprehensive and up-to-date exploration of the correlation between obesity and inflammation. From the pathophysiology of obesity and inflammation, to the molecular mechanisms of obesity induced chronic inflammation, the book discusses how obesity and inflammation interact with other diseases. It highlights the hidden risk factors of obesity induced chronic inflammation, provides specific patient management guidelines regarding the higher inflammatory response in patients, and concludes with new therapeutic strategies to address inflammation in obese patients.

Pediatric ESAP (TM) 2019-2020 Pediatric Endocrine Self-Assessment Program - Questions, Answers, Discussions, Reference Edition... Pediatric ESAP (TM) 2019-2020 Pediatric Endocrine Self-Assessment Program - Questions, Answers, Discussions, Reference Edition (Hardcover)
Paola A Palma Sisto
R2,189 Discovery Miles 21 890 Ships in 18 - 22 working days

Pediatric Endocrine Self-Assessment Program (Pediatric ESAP (TM)), Reference Edition, 2019-2020 is a self-study curriculum specifically designed for endocrinologists seeking initial certification or recertification in pediatric endocrinology, program directors interested in a training instrument, and clinicians and health professionals seeking a self-assessment and a broad review of pediatric endocrinology. Pediatric ESAP (TM) consists of 100 multiple-choice questions in all areas of pediatric endocrinology, diabetes, growth, and metabolism. There is extensive discussion of each correct answer and references. Pediatric ESAP (TM) is updated every two years with new questions. Customers are advised that this book is a reference edition and the questions in it are designed for self-study and reference. The content is the same as the non-reference edition, but CME and MOC credits are not available upon completion of the material. Anyone with questions about CME and/or MOC credits should consult www.endocrine.org/store for further information.

Super Gut - A Four-Week Plan to Reprogram Your Microbiome, Restore Health, and Lose Weight (Paperback): William Davis Super Gut - A Four-Week Plan to Reprogram Your Microbiome, Restore Health, and Lose Weight (Paperback)
William Davis
R534 R497 Discovery Miles 4 970 Save R37 (7%) Ships in 10 - 15 working days
Exploring Hypothyroidism (Hardcover): Benjamin Copes Exploring Hypothyroidism (Hardcover)
Benjamin Copes
R2,382 R2,175 Discovery Miles 21 750 Save R207 (9%) Ships in 18 - 22 working days
ESAP (TM) 2019: Endocrine Self-Assessment Program - Questions, Answers, Discussions, Reference Edition (Hardcover): Lisa R... ESAP (TM) 2019: Endocrine Self-Assessment Program - Questions, Answers, Discussions, Reference Edition (Hardcover)
Lisa R Tannock
R2,208 Discovery Miles 22 080 Ships in 18 - 22 working days

Endocrine Self-Assessment Program (ESAP (TM)), Reference Edition 2019 is a self-study curriculum for physicians and health professionals wanting a self assessment and a broad review of endocrinology. It consists of 120 brand-new multiple choice questions in all areas of endocrinology, diabetes, and metabolism. There is extensive discussion of each correct answer, a comprehensive syllabus, and references. ESAP is updated annually with new questions. Customers are advised that this book is a reference edition and the questions in it are designed for self-study and reference. The content is the same as the non-reference edition, but CME and MOC credits are not available upon completion of the material. Anyone with questions about CME and/or MOC credits should consult www.endocrine.org/store for further information.

The Path from Biomarker Discovery to Regulatory Qualification (Paperback): Federico Goodsaid, William B. Mattes The Path from Biomarker Discovery to Regulatory Qualification (Paperback)
Federico Goodsaid, William B. Mattes
R1,134 Discovery Miles 11 340 Ships in 10 - 15 working days

"The Path from Biomarker Discovery to Regulatory Qualification "is a unique guide that focuses on biomarker qualification, its history and current regulatory settings in both the US and abroad. This multi-contributed book provides a detailed look at the next step to developing biomarkers for clinical use and covers overall concepts, challenges, strategies and solutions based on the experiences of regulatory authorities and scientists. Members of the regulatory, pharmaceutical and biomarker development communities will benefit the most from using this book-it is a complete and practical guide to biomarker qualification, providing valuable insight to an ever-evolving and important area of regulatory science.

For complimentary access to chapter 13, "'""Classic' Biomarkers of Liver Injury, " by John R. Senior, Associate Director for Science, Food and Drug Administration, Silver Spring, Maryland, USA, please visit the following site: http: //tinyurl.com/ClassicBiomarkers
Contains a collection of experiences of different groups taking different types of biomarkers to different levels of qualification and provides insightful case studies of an important area of regulatory science

Focuses on practical advice, concepts, strategies and overall outcomes to support those working toward biomarker qualification for clinical use

Offers a valuable resource for members of the regulatory, pharmaceutical and biomarker development communities. "

Pathophysiology of Pulmonary Hypertension (Hardcover): Yuansheng Gao, J. Usha Raj Pathophysiology of Pulmonary Hypertension (Hardcover)
Yuansheng Gao, J. Usha Raj; Series edited by D. Neil Granger, Joey P Granger
R1,815 Discovery Miles 18 150 Ships in 18 - 22 working days

Pulmonary hypertension is a life-threatening disease with no known cure. Here we provide a concise yet comprehensive review of the current knowledge about the pathophysiology of pulmonary hypertension (PH). The underlying signaling mechanisms involved in pulmonary vascular remodeling and the exaggerated vascular contractility, two characteristic features of pulmonary hypertension, are discussed in depth. The roles of inflammation, immunity, and right ventricular function in the pathobiology of pulmonary hypertension are discussed. The epidemiology of the five groups of pulmonary hypertension (World Health Organization classification; Nice, 2013) is also briefly described. A clear understanding of our current knowledge about the pathogenesis of PH is essential for further exploration of the underlying mechanisms involved in this disease and for the development of new therapeutic modalities. This book should be of interest to researchers and graduate students, both in basic research and in clinical settings, in the fields of pulmonary vascular biology and pulmonary hypertension.

Occupational Ergonomics (Hardcover): Walter Lennox Occupational Ergonomics (Hardcover)
Walter Lennox
R2,823 R2,564 Discovery Miles 25 640 Save R259 (9%) Ships in 18 - 22 working days
Hypercalcemia, An Issue of Endocrinology and Metabolism Clinics of North America, Volume 50-4 (Hardcover): Claudio Marcocci,... Hypercalcemia, An Issue of Endocrinology and Metabolism Clinics of North America, Volume 50-4 (Hardcover)
Claudio Marcocci, Filomena Cetani
R2,399 Discovery Miles 23 990 Ships in 10 - 15 working days

Clinics Clinics

Actions for Kids age 1-3 (Engage Early Readers - Children's Learning Books) with FREE EBOOK (Hardcover): Dayna Martin Actions for Kids age 1-3 (Engage Early Readers - Children's Learning Books) with FREE EBOOK (Hardcover)
Dayna Martin; Edited by A.R. Roumanis
R559 Discovery Miles 5 590 Ships in 18 - 22 working days
Methodological Approaches for Sleep and Vigilance Research (Paperback): Eric Murillo-Rodriguez Methodological Approaches for Sleep and Vigilance Research (Paperback)
Eric Murillo-Rodriguez
R2,945 Discovery Miles 29 450 Ships in 10 - 15 working days

Methodological Approaches for Sleep and Vigilance Research examines experimental procedures used to study the sleep-wake cycle, with topics covered by world leaders in the field. The book focuses on techniques commonly used in the sleep field, including polysomnography, electrophysiology, single- and multi-unit spiking activity recording, brain stimulation, EEG power spectra, optogenetics, telemetry, and wearable and non-wearable tracking devices. Further chapters on imaging techniques, questionnaires for sleep assessment, genome-wide association studies, artificial intelligence and big data are also featured. This discussion of significant conceptual advances into experimental procedures is suitable for anyone interested in the neurobiology of sleep.

Recent Developments in Comparative Endocrinology and Neurobiology (Hardcover): Cooper Grant Recent Developments in Comparative Endocrinology and Neurobiology (Hardcover)
Cooper Grant
R3,480 R3,144 Discovery Miles 31 440 Save R336 (10%) Ships in 18 - 22 working days
Back to Basics in Physiology - Fluids in the Renal and Cardiovascular Systems (Paperback, New): Juan Pablo Arroyo, Adam J.... Back to Basics in Physiology - Fluids in the Renal and Cardiovascular Systems (Paperback, New)
Juan Pablo Arroyo, Adam J. Schweickert
R786 Discovery Miles 7 860 Ships in 10 - 15 working days

This original six chapter book will briefly review and integrate the basic concepts behind water distribution and movement in the body. This fills a knowledge gap that most medical and undergraduate physiology students acquire when these topics are studied separately. As of now, there is no textbook that fully integrates renal, cardiovascular and water physiology in a clear understandable manner. The book is intended primarily for medical students and undergraduate physiology students. Chapters include: 1) Water and its Distribution; 2) Water Dynamics; 3) Fluid Handling by the Heart and Blood Vessels; 4) Fluid Handling by the Kidneys; 5) Water and Oxygen Delivery; 6) Integration in the Response to Hemorrhage, Volume Depletion, and Water Redistribution.
An easy-to-read, step by step explanation of how water is distributed, how it moves, how this aides in oxygen delivery and how this is regulated in the human body.

Presentsa complex and detailed topicin an original way that will allow students to understand more complex textbooks and explanations"

Exercise Physiology: Nutrition, Energy, and Human Performance (Hardcover, Ninth, International Edition, Revised Reprint):... Exercise Physiology: Nutrition, Energy, and Human Performance (Hardcover, Ninth, International Edition, Revised Reprint)
William McArdle, Frank I. Katch, Victor L. Katch
R1,922 Discovery Miles 19 220 Ships in 10 - 15 working days
Human Growth and Development (Paperback, 3rd edition): Noel Cameron, Lawrence Schell Human Growth and Development (Paperback, 3rd edition)
Noel Cameron, Lawrence Schell
R2,678 Discovery Miles 26 780 Ships in 10 - 15 working days

Human Growth and Development, Third Edition provides a comprehensive volume covering the biology of human growth and the genetic, endocrine, environmental, nutritional, and socio-economic factors that contribute towards its full expression. Human Growth and Development continues to be a valuable resource for researchers, professors and graduate students across the interdisciplinary area of human development. For the new edition, updates are made to all fourteen of the "core chapters" of the book which form the essential reading for a comprehensive understanding of human growth and development. Additionally, new special topics are covered including the interpretation of recently found sub-adult fossils that expand our understanding of the evolution of human growth and a discussion of the early pattern of growth and development as the developmental origins of risk for non-communicable diseases of adulthood. Human Growth and Development, Third Edition includes contributions from the well-known experts in the field and is the most reputable, comprehensive resource available.

Regenerative Nephrology (Hardcover, 2nd edition): Michael S. Goligorsky Regenerative Nephrology (Hardcover, 2nd edition)
Michael S. Goligorsky
R3,569 Discovery Miles 35 690 Ships in 10 - 15 working days

Since the publication of the first edition of this book in 2010, an explosion of spectacular discoveries in the field of regeneration has compelled the current revisit of the field of Regenerative Nephrology. This second edition features subjects as diverse as age and gender influencing regenerative processes; mechanisms and pathways of premature cell senescence affecting kidney regeneration; the ways intrinsic regenerative processes can become subverted by noxious stressors eventuating in disease progression; novel mechanistic and engineering efforts to recreate functional kidney or its component parts; cell reprogramming and reconditioning as emerging tools of future regenerative efforts; and effects of various biologicals on kidney regeneration. These newer additions to the armamentarium of Regenerative Medicine and Nephrology have become an integral part of the second edition of the book. Cutting-edge investigations are summarized by the constellation of the most experienced contributing authors coming together from around the world under the umbrella of the second edition.

Endocrinology Adult and Pediatric: The Parathyroid Gland and Bone Metabolism (Paperback, 6th edition): John T. Potts, J.Larry... Endocrinology Adult and Pediatric: The Parathyroid Gland and Bone Metabolism (Paperback, 6th edition)
John T. Potts, J.Larry Jameson, Leslie J. DeGroot
R876 Discovery Miles 8 760 Ships in 10 - 15 working days

Effectively manage parathyroid and bone metabolism disorders with The Parathyroid Gland and Bone Metabolism! Brought to you by the same leading endocrinologists responsible for the highly acclaimed two-volume textbook, Endocrinology: Adult and Pediatric, this derivative book presents a compilation of chapters covering all endocrinology material related to parathyroid and bone metabolism. Never before available as a stand-alone offering, this content will enable you to give your patients the benefit of today's best know-how on parathyroid and bone metabolism from the leading resource in endocrinology. Stay abreast of the newest knowledge and advances on parathyroid and bone metabolism, including. pediatric parathyroid disorders and bone metabolism disorders major diseases common to the aging population such as osteoporosis advances in the genetics of disorders involving calciotropic hormones newer diagnostic approaches and therapies for bone diseases, from osteoporosis to Paget's disease and much more. Count on all the authority that has made Endocrinology, 6th Edition, edited by Drs. Jameson and De Groot, the go-to clinical medical reference for endocrinologists worldwide. Make the best clinical decisions with an enhanced emphasis on evidence-based practice in conjunction with expert opinion.

Global Emergency of Mental Disorders (Paperback): Jahangir Moini, Justin Koenitzer, Anthony Logalbo Global Emergency of Mental Disorders (Paperback)
Jahangir Moini, Justin Koenitzer, Anthony Logalbo
R4,041 Discovery Miles 40 410 Ships in 10 - 15 working days

Global Emergency of Mental Disorders is a comprehensive, yet easy-to-read overview of the neurodevelopmental basis of multiple mental disorders and their accompanying consequences, including addiction, suicide and homelessness. Compared to other references that examine the treatment of psychiatric disorders, this book uniquely focuses on their neurodevelopment. It is designed for neuroscience, psychiatry, psychology students, and various other clinical professions. With chapters on anxiety, depression, schizophrenia and others, this volume provides information about incidence, prevalence and mortality rates in addition to developmental origins. With millions worldwide affected, this book will be an invaluable resource.

Hormones, Metabolism and the Benefits of Exercise (Hardcover): Bruce Spiegelman Hormones, Metabolism and the Benefits of Exercise (Hardcover)
Bruce Spiegelman
R1,229 Discovery Miles 12 290 Ships in 18 - 22 working days
The Endocannabinoid System in Local and Systemic Inflammation (Hardcover): Melanie E M Kelly, Christian Lehmann, Juan Zhou The Endocannabinoid System in Local and Systemic Inflammation (Hardcover)
Melanie E M Kelly, Christian Lehmann, Juan Zhou
R2,380 Discovery Miles 23 800 Ships in 18 - 22 working days

This book focuses on the role of the endocannabinoid system in local and systemic inflammation, with individual chapters written by experts in the field of cannabinoid research and medicine. The topics explore the actions of the endocannabinoid system on the immune system, including neuroinflammation in autoimmune disorders such as multiple sclerosis, and in neurodegenerative disorders such as Huntington's and Alzheimer's, as well as local and systemic inflammatory conditions affecting organs including the eye (uveitis and corneal inflammation), the bladder (interstitial cystitis), pancreas (diabetes), cardiovascular system (stroke), joints (arthritis), and sepsis. The objective of this book is to provide knowledge transfer on the use of cannabinoids in inflammatory disease by critically examining preclinical and clinical research on the immunomodulatory actions of the endocannabinoid system, with specific emphasis on the actions of cannabinoids in diseases where inflammation is a prominent component. By drawing these results together, we seek to provide further understanding of the complexities of endocannabinoid system modulation of immune function and identify potential uses and limitations for cannabinoid-based therapeutics.

2018 Meet-the-Professor Endocrine Case Management - Reference Edition (Hardcover): Ann Danoff 2018 Meet-the-Professor Endocrine Case Management - Reference Edition (Hardcover)
Ann Danoff
R2,261 Discovery Miles 22 610 Ships in 18 - 22 working days

Meet-the-Professor (MTP) Endocrine Case Management, Reference Edition 2018 is your source for the latest updates in the diagnosis and management of a wide range of endocrine disorders. This valuable resource allows you to evaluate your endocrine knowledge and gain insight into the strategies used by clinical experts. MTP is updated annually with new cases. Features include: Significance of the Clinical Problem. Key Learning Objectives. Strategies for Diagnosis and Management. Clinical Pearls and Pertinent References. Cases and Questions. Customers are advised that this book is a reference edition and the questions in it are designed for self-study and reference. The content is the same as the non-reference edition, but CME and MOC credits are not available upon completion of the material. Anyone with questions about CME and/or MOC credits should consult www.endocrine.org/store for further information.

Recent Advances in the Pathogenesis, Prevention and Management of Type 2 Diabetes and its Complications (Hardcover): Mark... Recent Advances in the Pathogenesis, Prevention and Management of Type 2 Diabetes and its Complications (Hardcover)
Mark Zimering
R3,625 Discovery Miles 36 250 Ships in 18 - 22 working days
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