Sunday Times bestseller We have a lifetime's association with our bodies, but for many of us they remain uncharted territory. In Adventures in Human Being, Gavin Francis leads the reader on a journey through health and illness, offering insights on everything from the ribbed surface of the brain to the secret workings of the heart and the womb; from the pulse of life at the wrist to the unique engineering of the foot. Drawing on his own experiences as a doctor and GP, he blends first-hand case studies with reflections on the way the body has been imagined and portrayed over the millennia. If the body is a foreign country, then to practise medicine is to explore new territory: Francis leads the reader on an adventure through what it means to be human. Both a user's guide to the body and a celebration of its elegance, this book will transform the way you think about being alive, whether in sickness or in health. Published in association with the Wellcome Collection. WELLCOME COLLECTION Wellcome Collection is a free museum and library that aims to challenge how we think and feel about health. Inspired by the medical objects and curiosities collected by Henry Wellcome, it connects science, medicine, life and art. Wellcome Collection exhibitions, events and books explore a diverse range of subjects, including consciousness, forensic medicine, emotions, sexology, identity and death. Wellcome Collection is part of Wellcome, a global charitable foundation that exists to improve health for everyone by helping great ideas to thrive, funding over 14,000 researchers and projects in more than 70 countries. wellcomecollection.org

'Pontzer's findings have huge implications for our attitudes to exercise, diet and public health' Mark Webster, Sunday Times A myth-busting tour of the body's hidden foundations from a pioneering evolutionary biologist 'Public health strategies stubbornly cling to the simplistic armchair engineer's view of metabolism, hurting efforts to combat obesity, diabetes, heart disease, cancer, and the other diseases that are most likely to kill us' Herman Pontzer's ground-breaking research has revealed how, contrary to received wisdom, exercise does not increase our metabolism. Instead, we burn calories within a very narrow range: nearly 3,000 calories per day, no matter our activity level. In this book, he draws on twenty years of cutting-edge science to take a closer look at what happens to the energy we consume. Burn explores the ways in which metabolism controls every aspect of our health - from fertility to immune function - and reveals the truth about the dynamic system that sustains us. Filled with facts and memorable anecdotes, this book will change the way you think about food, exercise and what really matters for your health.

Die vollstandig uberarbeitete 2. Auflage dieses Lehrbuchs spiegelt die Leitlinien des Curriculums angehender Pflegekrafte wider und enthalt ein neues Kapitel zu Wachstum und Entwicklung von Kindern und Jugendlichen. Daruber hinaus werden u. a. soziale, politische und Umwelteinflusse auf die Gesundheit und das Wohlergehen von Kindern betrachtet. Problem- und Fragenstellungen wurden aktualisiert. Jedes Kapitel bietet eine Vielzahl wirkungsvoller padagogischer Handreichungen, darunter Lernziele, klinische Betrachtungen, Koerperschemata und Fragen zur Selbstuberprufung des Lernstoffes. Dieses fuhrende Lehrbuch, das Studenten darauf vorbereitet, in ihrem zukunftigen Arbeitsalltag Kinder und Jugendliche wirkungsvoll zu betreuen, - beschaftigt sich mit den anatomischen und physiologischen Veranderungen mit Auswirkungen auf den Gesundheitszustand. - legt den Schwerpunkt durchgangig auf die klinische Anwendung und verbindet Anatomie und Physiologie mit haufigen Gesundheitsstoerungen bei Kindern. - folgt einem strukturieren und umfassenden Ansatz in Zusammenhang mit den theoretischen Grundlagen der Anatomie und Physiologie bei Kindern und bereitet die Studenten auf die Praxis vor. - bietet zusatzliche Online-Materialien, wie Multiple-Choice-Fragen, interaktive Flashcards, durchsuchbare Glossare und Literaturverweise. Fundamentals of Children and Young People's Anatomy and Physiology ist ein Muss fur angehende Pflegekrafte und Studenten medizinischer Fachrichtungen und ein nutzliches Referenzwerk fur Pflegekrafte, Pflegehelfer, Gesundheitsassistenten und weitere Berufsgruppen aus dem Fachgebiet.

For courses in Human Physiology. Move beyond memorisation: Prepare students for tomorrow's challenges Human Physiology: An Integrated Approach is the #1 best-selling 1-semester human physiology text world-wide. The 8th Edition engages students in developing a deeper understanding of human physiology by guiding them to think critically and equipping them to solve real-world problems. Updates, such as new Try It activities and detailed teaching suggestions in the new Ready-to-Go Teaching Modules, help students learn and apply mapping skills, graphing skills, and data interpretation skills. The text reflects Dr. Silverthorn's active learning style of instruction and builds upon the thorough integration of "big picture" themes with up-to-date cellular and molecular physiology topics that have always been the foundation of her approach.

Containing all the new as well as classical methodologies used in the investigation of amino acid and protein metabolism in human and animal models, this book is needed because of the dramatic increase in research in this field. There is no other book currently on the market that covers these methods of investigation. Methods for Investigation of Amino Acid and Protein Metabolism explores areas such as amino acid transfer across tissue membranes, past and new applications using stable isotopes, protein synthesis in organs and tissues, and more. Because of the importance of research methods in the field of amino acid and protein nutrition and metabolism, this book facilitates the reader's integration of the concepts involved in these investigative research methods and their corollaries. In addition to helping any nutrition investigator design and conduct appropriate research protocols in this area of nutrition, this book assists students who are planning to investigate amino acid and protein metabolism in humans or laboratory animals.

Strength and power are recognised as key components of human health and performance. Therefore, it is vital for exercise scientists and strength and conditioning practitioners to be able to assess these qualities effectively. Testing methods of these components are often presented as standalone chapters in textbooks which provides the reader with an overview of these aspects. Testing and Evaluation of Strength and Power provides a detailed explanation of testing and evaluation methods for strength and power. The book considers the relationship between the methods of assessment, research on the various approaches to evaluation and how practitioners and researchers can use the information in applied settings. The book provides the reader with a comprehensive overview of methods of strength and power assessment protocols and how they can be used to inform programming. This integrated approach to assessment of strength and power is recommended reading for students on strength and conditioning course and of vital reading to those on specialised courses on strength and power as well as coaches in the fitness testing and strength and conditioning disciplines.

Featuring practical strategies and exciting experiments, Teaching Innovations in Lipid Science addresses lipid education at a range of levels from the novice to the graduate student and teacher. Peer-reviewed contributions from internationally known specialists, describe several methods and approaches designed to create new lipid courses, modify existing courses, and serve as a basis for pursuing novel avenues of instruction. Divided into two sections, the first focuses on teaching strategies and outlines some of the barriers that lipid science specialists face when transmitting accurate information. It emphasizes the development and implementation of creative programs that foster interest in lipid science, and presents novel problem-solving approaches. It discusses strategies for involving and evaluating independent study students and explains the successful use of sample cards to teach oilseed and cereal processing. This section also provides generalized accounts of biotechnology and crop improvement and isoprenoid biochemistry, including improvement of oilseed crops and tips on explaining DNA science and crop biotechnology. The second section begins with simple demonstrations on the physical properties of lipids suitable for middle- and high school students. It follows with more complex experiments on analyzing lipids in food oils, plasma, and milk utilizing thin layer chromatography, gas chromatography, and high performance liquid chromatography. Contributions include information on convenient enzyme test kits with exercises that can translate to a lab course beginning with chromatographic methods for lipid analysis. The final chapter presents theory and experiments for studying lipid metabolism in the plastid by describing preparation methods, studying metabolite uptake, and pathway analysis.

The ability to regulate and manipulate the generation or remodeling of blood vessels is key to the successful treatment of many chronic diseases, both oncological and non-oncological. Several bioactive compounds present in human diets are now known to exert an inhibitive effect on the either the signaling or construction of new blood vessels. The identification and characterization of these anti-angiogenic molecules opens a new avenue for the research and production of functional and medicinal foods with far reaching implications for the food-based treatment of chronic degenerative disease. Drawing from an extensive list of esteemed international contributors, Anti-Angiogenic Functional and Medicinal Foods explores the history and scope of the use of conventional foods, nutraceuticals, and health products in North America, Europe, the Middle East, Asia, India, Australia, and New Zealand. Recent advancements in proteomics, genomics, and toxicogenomics give us a far more detailed picture of the molecular basis of nutrition and systems toxicology. Explaining the role of angiogenesis in various chronic diseases, individual chapters consider endothelial cell responses, the mechanism of the angiogenic cascade, and the angiogenic function involved in tumors, cardiovascular disease, inflammatory arthritis, and obesity. A collection of chapters studies specific foods and their functional bioactive compounds such as the effects of edible berry anthocyanins, various Chinese medicinal foods, dietary flavonoids, probiotics, shark cartilage, EPA and DHA, and marine polysaccharides. The book concludes with a discussion of the challenges faced during the development and delivery of anti-angiogenic functional food products. Presenting the current research and state of the science, Anti-Angiogenic Functional and Medicinal Foods provides researchers, scientists, clinical nutritionists, and oncologists with a valuable reference to this important and growing mode of

This book systematically introduces the bionic nature of force sensing and control, the biomechanical principle on mechanism of force generation and control of skeletal muscle, and related applications in robotic exoskeleton. The book focuses on three main aspects: muscle force generation principle and biomechanical model, exoskeleton robot technology based on skeletal muscle biomechanical model, and SMA-based bionic skeletal muscle technology. This comprehensive and in-depth book presents the author's research experience and achievements of many years to readers in an effort to promote academic exchanges in this field. About the Author Yuehong Yin received his B.E. , M.S. and Ph.D. degrees from Nanjing University of Aeronautics and Astronautics, Nanjing, in 1990, 1995 and 1997, respectively, all in mechanical engineering. From December 1997 to December 1999, he was a Postdoctoral Fellow with Zhejiang University, Hangzhou, China, where he became an Associate Professor in July 1999. Since December 1999, he has been with the Robotics Institute, Shanghai Jiao Tong University, Shanghai, China, where he became a Professor and a Tenure Professor in December 2005 and January 2016, respectively. His research interests include robotics, force control, exoskeleton robot, molecular motor, artificial limb, robotic assembly, reconfigurable assembly system, and augmented reality. Dr. Yin is a fellow of the International Academy of Production Engineering (CIRP).

The advances made in vascular biology in the last 25 years have considerably changed the perception that one could have of the endothelial cells. Once considered as a diffusion barrier preventing the access of the blood cells to the vascular matrix, the endothelium is now recognized as playing a major role in the control of blood fluidity, platelet aggregation, and vascular tone, but also in immunology, inflammation, angiogenesis, and for serving as a metabolizing and an endocrine organ. -- from the preface Cardiovascular diseases, so prevalent in the Western world during the twentieth century, could well become the scourge of the twenty-first century in emerging countries as well as the West. Endothelial dysfunction linked to an imbalance in the synthesis and/or release of contracting and relaxing factors is often evoked to explain the initiation of the cardiovascular pathology or its development and perpetuation. Two decades ago, when nitric oxide was demonstrated to mediate endothelium-dependent relaxations, the vascular world seemed convinced that nitric oxide was the ultimate and sole explanation for such relaxations. However not everyone agreed. EDHF: The Complete Story is the work of two leading researchers who did not accept that simple conclusion, but instead continued to search, along with others, for a deeper understanding of the ways in which endothelial cells communicate with the underlying smooth muscle to signal it to hyperpolarize. Now with most, if not all, of those ways, uncovered, the authors offer this summary as way of bringing closure to the quest. This monograph reports on the work of many researchers. It summarizes the significant recent discoveries concerning endothelium-dependent hyperpolarizations, which are likely to play a much more important role in cardiovascular physiology and pathology than was originally foreseen Extensively illustrated with original diagrams and schematics that su

With an ever-expanding array of biomaterials and implant devices appearing in the field, Spinal Reconstruction: Clinical Examples of Applied Basic Science, Biomechanics and Engineering helps surgeons assess and utilize the latest technologies to improve the reconstruction of the spine and enhance the reconstitution of diseased spinal segments. With illustrative descriptions of specific clinical scenarios, this guide helps surgeons select the best devices and materials for reconstructive procedures and considers issues in biocompatibility, biostability, and structure-function relationships for enhanced patient outcomes and mobility. With more than 350 figures and photographs, this book: Details current strategies in minimally invasive spine surgery as currently applied to the lumbar spine Covers the myriad of patient factors, orthobiologic grafting alternatives, and technique-driven mechanical options encountered in spinal care and reconstruction Identifies new surgical techniques for spinal fusion, vertebral compression fractures, and arthroplasty Discusses the basic mechanisms and clinical application of currently available operative treatments Supplies the most up-to-date information on the evaluation, diagnosis, and operative treatment of spinal pain, deformity, and disease

Golf is one of the world's major sports and consequently the focus of world-class scientific research. This landmark publication is the most comprehensive book ever published on the science of golf, covering every sub-discipline from physiology, biomechanics and psychology to strength and conditioning, youth development and equipment design. Showcasing original research from leading golf scientists across the globe, it examines the fundamental science underpinning the game and demonstrates how it can be applied in practice to improve and develop players. Each chapter provides a definitive account of the current state of knowledge in a particular area of golf science, addressing the limitations of existing research, presenting new areas for development and discussing the implications for coaches, players, scientists and the wider golfing public. Truly international in scope, the variety of topics explored include: biomechanics and equipment skill learning and technology performance development psychological techniques for success the golfing body. This is an essential reference for any student or researcher with an interest in the game, or any coach or professional looking to improve their knowledge.

In recent times, the ASEP (American Society of Exercise Physiologists) leaders have developed and implemented academic standards to promote professionalism in academic programs throughout the U.S. The effort represents a significant change in the scope and the monitoring of the exercise physiologists' accountability. Through these new standards, all academic exercise physiologists are challenged by ASEP to accept responsibility for promoting the professionalization and self-regulation that will lead to lead to improved client and patient care when prescribing exercise medicine. Accreditation helps to reduce unnecessary variation within and between academic programs. Moreover, given the collaborative improvement in academic programs and faculty responsibility to the undergraduate students, the quality of their educational care will be significantly improved. Academic exercise physiologists must take responsibility for where exercise physiology is today and take responsibility to the evolving state of exercise physiology and student market-driven career opportunities in exercise medicine. Advancing the Profession of Exercise Physiology provides understanding and guidance on the importance and the significance of academic leadership in promoting the profession of exercise physiology as a healthcare profession that is founded on professionalism, accreditation, ethical practice, and entrepreneurial skills. This new volume examines the ethical need for professionalism in exercise physiology, which is, in turn, imperative for future growth and sustainability.

This book examines how the growing knowledge of the huge range of protist-, animal-, and plant-bacterial interactions, whether in shared ecosystems or intimate symbioses, is fundamentally altering our understanding of biology. The establishment and maintenance of these interactions and their contributions to the health and survival of all partners relies on continuous cell-to-cell communication between them. This dialogue may be concerned with all aspects of the biology of both partners. The book includes chapters devoted to exploring, explaining, and exposing these dialogues across a broad spectrum of plant and animal eukaryotes to a broad field of biologists. Key Features Explores the nature of the interactions between eukaryotic hosts and their microbial symbionts Examines the links between prostist, animal, and plant evolution and microbial communities Reviews specific taxa and the microbial diversity associated with these taxa Illustrates the role microbes play in the physiology and etiology of several model species Includes chapters by an international team of leading scholars

In recent times, the ASEP (American Society of Exercise Physiologists) leaders have developed and implemented academic standards to promote professionalism in academic programs throughout the U.S. The effort represents a significant change in the scope and the monitoring of the exercise physiologists' accountability. Through these new standards, all academic exercise physiologists are challenged by ASEP to accept responsibility for promoting the professionalization and self-regulation that will lead to lead to improved client and patient care when prescribing exercise medicine. Accreditation helps to reduce unnecessary variation within and between academic programs. Moreover, given the collaborative improvement in academic programs and faculty responsibility to the undergraduate students, the quality of their educational care will be significantly improved. Academic exercise physiologists must take responsibility for where exercise physiology is today and take responsibility to the evolving state of exercise physiology and student market-driven career opportunities in exercise medicine. Advancing the Profession of Exercise Physiology provides understanding and guidance on the importance and the significance of academic leadership in promoting the profession of exercise physiology as a healthcare profession that is founded on professionalism, accreditation, ethical practice, and entrepreneurial skills. This new volume examines the ethical need for professionalism in exercise physiology, which is, in turn, imperative for future growth and sustainability.

An NRC Handelsblad Book of the Year "Offers rich discussions of olfactory perception, the conscious and subconscious impacts of smell on behavior and emotion." -Science Decades of cognition research have shown that external stimuli "spark" neural patterns in particular regions of the brain. We think of the brain as a space we can map: here it responds to faces, there it perceives a sensation. But the sense of smell-only recently attracting broader attention in neuroscience-doesn't work this way. So what does the nose tell the brain, and how does the brain understand it? A. S. Barwich turned to experts in neuroscience, psychology, chemistry, and perfumery in an effort to understand the mechanics and meaning of odors. She discovered that scents are often fickle, and do not line up with well-defined neural regions. Upending existing theories of perception, Smellosophy offers a new model for understanding how the brain senses and processes odors. "A beguiling analysis of olfactory experience that is fast becoming a core reference work in the field." -Irish Times "Lively, authoritative...Aims to rehabilitate smell's neglected and marginalized status." -Wall Street Journal "This is a special book...It teaches readers a lot about olfaction. It teaches us even more about what philosophy can be." -Times Literary Supplement

Now in its fourteenth edition, this best-selling textbook has been honed over many years to provide a clear, straightforward introduction to the human body for students of nursing, allied health or biomedical and paramedical science. The book covers the core essentials of anatomy and physiology, including basic pathology and pathophysiology of important diseases and disorders. This new edition presents additional illustrations to enhance understanding of key concepts, including pathophysiology and diagnostics. Included for the first time is an introduction to surface anatomy, while other updating reflects current scientific knowledge and developments, including coronavirus. Enhanced learning features and an extensive online resource help you grasp all the important areas. Like millions of readers before you, you will treasure Ross & Wilson as a go-to resource that you will refer to time and again to support this critical aspect of your healthcare education. Clear and easy to read - suitable for students new to the area and anyone whose first language is not English Hundreds of stunning illustrations and images to make learning easy Helpful learning features such as Learning Outcomes boxes, colour coding and orientation icons to facilitate navigation Definitions of common prefixes, suffixes and roots, examples, glossary and an appendix of normal biological values Self-assessment activities in each chapter, including 'spot check' questions for each section and case studies with answers to develop understanding of key principles Accompanying website with animations, videos, audio-glossary and other self-assessment material Evolve Study Resources Online content offered with Ross & Wilson Anatomy and Physiology in Health and Illness 14th edition includes: New for this edition - a set of expert-narrated 3D videos summarizing key topics in the book, powered by Complete Anatomy: the world's most advanced 3D anatomy platform Over 120 animations clarifying underlying principles and make learning fun More than 1700 audio glossary entries Body Spectrum (c) online colouring and self-test software Self-assessment questions to help students test their knowledge

Fatigue is a condition spanning the breadth of human functioning in health and disease and is a central concern in sport and exercise. Even so we are yet to fully understand its causes. One reason for this lack of understanding is that we seldom consider fatigue from an evolutionary perspective - as an adaptation that provided reproductive success. This ground-breaking book outlines the evidence that fatigue is a result of adaptations distinctive to humans. It argues that humans developed adaptations which led to enhanced fatigue resistance compared with other mammals and discusses the implications in the context of exercise, health and performance. Highly illustrated throughout, it covers topics such as defining and measuring fatigue, the emotional aspect of fatigue, how thermoregulation affects the human capacity to resist fatigue, and fatigue in disease. Human Fatigue is essential reading for all exercise scientists as well as graduate and undergraduate students in the broad field of physiology and exercise physiology.

Volume I of this book provides a comprehensive discussion of the factors involved in regulation of the cell cycle, the general biological properties of growth factors, and the receptor and postreceptor mechanisms of action of these signaling agents. It evaluates the possible role of growth factors in the regulation of proto-oncogene and tumor suppressor gene expression, and the development of neoplastic processes is discussed in detail.

Fundamental Biomechanics of Sport and Exercise is an engaging and comprehensive introductory textbook that explains biomechanical concepts from first principles, showing clearly how the science relates to real sport and exercise situations. The book is divided into two parts. The first provides a clear and detailed introduction to the structure and function of the human musculoskeletal system and its structural adaptations, essential for a thorough understanding of human movement. The second part focuses on the biomechanics of movement, describing the forces that act on the human body and the effects of those forces on the movement of the body. Every chapter includes numerous applied examples from sport and exercise, helping the student to understand how mechanical concepts describe both simple and complex movements, from running and jumping to pole-vaulting or kicking a football. In addition, innovative worksheets for field and laboratory work are included that contain clear objectives, a description of method, data recording sheets, plus a set of exemplary data and worked analysis. Alongside these useful features are definitions of key terms plus review questions to aid student learning, with detailed solutions provided for all numerical questions. No other textbook offers such a clear, easy-to-understand introduction to the fundamentals of biomechanics. This is an essential textbook for any biomechanics course taken as part of degree programme in sport and exercise science, kinesiology, physical therapy, sports coaching or athletic training.

Roiger and Bullock's unique pedagogical and visual approach helps students make the important connections between systems and learn how the body functions normally in homeostasis, and how disruption of homeostasis leads to disease and disorder. With a straightforward, engaging writing style, the authors explain difficult concepts in the context of routine activities, making concepts easier to grasp. Measurable learning outcomes throughout the textbook, workbook, and digital learning and assessment program help direct students through the content so there are no surprises. Anatomy, Physiology, Disease requires no prior knowledge of chemistry or cell biology, and is designed for an anatomy and physiology course or an anatomy, physiology, and pathology course. It is neither too high nor too low and can be customized to accommodate the organization of individual courses.

Bone is a complex biological material that consists of both an inorganic and organic phase, which undergoes continuous dynamic biological processes within the body. This complex structure and the need to acquire accurate data have resulted in a wide variety of methods applied in the physical analysis of bone in vivo and in vitro. Each method has its own strengths and applications depending on the information sought by the clinician or researcher. The Physical Measurement of Bone provides a detailed description of all the major methods of bone analysis, including brief comments on clinical evaluation. The physics of each method are introduced as well as a summary of practical procedures. The book is essential reading for practicing medical physicists and technicians who need to know about the many methods of bone analysis open to them, and, more importantly, the wide coverage provides a good introductory framework for students of medical physics and biomedical engineering.

Controversies in Exercise Science introduces a series of selected unresolved issues in the field of human exercise science. The common thread to all of these topics is that, in their ultimate resolution, they offer promise of insights into the essential principles of physiological systems and how these respond to the stresses of exercise. Each case study includes an examination of research surrounding each issue; the innovative aspect, however, will be that each of these controversies will be presented in the context of an historical and/or philosophical perspective. These chapter include topics related to basic exercise physiology, sports, physical activity, and exercise health. Underlying each of these debates lie clues which may offer insights into the basic nature of living beings. Aimed at both academics and practitioners in the fields of exercise science, biology, and related sports science disciplines, Controversies in Exercise Science provides arguments for both sides of several selected contemporary controversies in the field of exercise science and, while no ultimate resolution will be provided, the goal is, rather, to offer the reader sufficient "raw material" on which he or she might make their own judgement on the matters presented.

An innovative theory proposes a new therapeutic strategy to break the stalemate in the war on cancer. It is called cancer stem cell (CSC) theory, and Lucie Laplane offers a comprehensive analysis, based on an original interdisciplinary approach that combines biology, biomedical history, and philosophy. Rather than treat cancer by aggressively trying to eliminate all cancerous cells-with harmful side effects for patients-CSC theory suggests the possibility of targeting the CSCs, a small fraction of cells that lie at the root of cancers. CSCs are cancer cells that also have the defining properties of stem cells-the abilities to self-renew and to differentiate. According to this theory, only CSCs and no other cancer cells can induce tumor formation. To date, researchers have not agreed on the defining feature of CSCs-their stemness. Drawing from a philosophical perspective, Laplane shows that there are four possible ways to understand this property: stemness can be categorical (an intrinsic property of stem cells), dispositional (an intrinsic property whose expression depends on external stimuli), relational (an extrinsic property determined by a cell's relationship with the microenvironment), or systemic (an extrinsic property controlled at the system level). Our ability to cure cancers may well depend upon determining how these definitions apply to different types of cancers.