This book provides a comprehensive account of the current status of molecular hydrogen medicine, a young field that emerged with the discovery that inhalation of hydrogen gas leads to the elimination of harmful reactive oxygen species in rats. Various physiologic effects have since been demonstrated, and possible medical applications identified. Numerous clinical projects have now been undertaken, yielding startling results. Despite this, molecular hydrogen medicine remains underappreciated among the medical community at large. The author aims to rectify this situation by fairly but critically evaluating the potential clinical benefits based on the latest scientific research. In addition, the observed physiological effects of hydrogen gas are considered within the broad context of the evolution of life on earth, offering new perspectives and helping to place molecular hydrogen medicine legitimately within the framework of life sciences. Written in an accessible manner, the book will be of value to students, researchers, clinicians, and the general public.

Designed with speed and simplicity in mind, this pocket-sized glossary provides an A-Z reference guide to over 1,900 key biological terms used in nursing. Key Features: 1. Prepare for practice - Clear definitions of commonly used terminology 2. Learn the language - Phonics-based guidance on pronunciation 3. Deepen your knowledge - Breaks down complex terms to aid understanding

Ideal for all health care professionals who evaluate, diagnose, treat, or refer patients with endocrine disease or disorders, Manual of Endocrinology and Metabolism, Fifth Edition , brings together nearly 150 global authorities who share their knowledge and expertise on endocrine disorders in children, adolescents, and adults. Using a concise outline format, this thoroughly updated manual presents clinical information and protocols needed in everyday practice, with an emphasis on diagnosis and treatment. Succinct chapters and an abundance of tables and diagrams make complex information easy to find and understand. Includes coverage of fundamental understandings and treatment modalities as well as recent therapies, new methods of treatment, new understandings of endocrine physiology, and new surgical approaches to disease states Covers evaluation, pathophysiology, management, and treatment at every age of life, along with short- and long-term goals of reversibility and prevention New chapters include transgender medicine, flushing and sweating, nasal administration of hormones, the growth plate, as well as traumatic brain injury and hypopituitarism New topics include galactorrhea; preoperative, intraoperative, and postoperative management following pituitary surgery; growth hormone in adults, polycystic ovary syndrome, hypercalcemic crisis, parathyroid hormone-related protein, congenital hyperinsulinism, and hypokalemic periodic and non-periodic paralysis New and expanded coverage of diabetes mellitus includes hypoglycemia-associated autonomic failure, glucocorticoid-induced hyperglycemia, C-peptide, cystic fibrosis-related diabetes, the artificial pancreas, glycated proteins, inhaled insulin, and the application of stem cells in diabetes mellitus Serves as an excellent resource for board preparation, as well as a concise daily reference for endocrinologists, general practitioners, internists, pediatricians, physician assistants, nurse practitioners, and others who see patients with primary or underlying endocrine disease Enrich Your eBook Reading Experience with Enhanced Video, Audio and Interactive Capabilities! Read directly on your preferred device(s ), such as computer, tablet, or smartphone Easily convert to audiobook , powering your content with natural language text-to-speech Adapt for unique reading needs , supporting learning disabilities, visual/auditory impairments, second-language or literacy challenges, and more

Systemic lupus erythematosus (SLE) is one of the prototypical systemic autoimmune diseases characterised by inflammation, immune complex deposition, and vasculitis. Patients with SLE show various symptoms and clinical images, both constitutional and specific organ symptoms. They include the skin, joints, muscles, kidneys, lungs, nervous system, and blood vessels. Although the aetiology of the disease is still unclear, genetic, hormonal, immunologic abnormalities and environmental factors complicatedly play important roles in the pathophysiology in SLE. It is evident that multiple genes show genetic susceptibility to SLE. Environmental factors of SLE and immunologic abnormalities, especially the production of a number of auto-antibody, are important features of the disease. In this book, we present recent knowledge about the prevalence, pathophysiology and prognosis of SLE. The book includes various interesting chapters: Chapter One: An illustrated overview of the prevalence and clinical symptoms of systemic lupus erythematosus; Chapter Two: Pathophysiology of systemic lupus erythematosus; Chapter Three: MBL and MBL genotypes in SLE; Chapter Four: Novel biological activities of autoantibodies as the potential markers of systematic lupus erythematosus; Chapter Five: Cytokines in systemic lupus erythematosus (sle) with clinical aspects and prognostics; Chapter Six: Prognosis in systemic lupus erythematosus; Chapter Seven: Auto-antibody-producing RP105-negative B cells in humans and a murine model of lupus erythematosus.

Mind-Body Awareness for Singers provides a fundamental understanding of functional anatomy and cognitive neuroscience, which guides singers and teachers of singing in unlocking the mystery of the mind-body link. New theories and concepts, rooted in both the wisdom of the masters and current and unique scientific research, are introduced from the refreshingly meaningful internal perspective of the performer. Practical-application exercises train the mind of the singer to work with, rather than at cross purposes with, the systems of singing.. Performers learn how to integrate the cognitive and conscious, the imaginative and alert mind, with the subconscious sensory and motor processes of our nervous system to intuitively guide elite integration of the complex audio-motor behavior that is singing. By mapping not only the body's musculoskeletal structure but also the body's voluntary and involuntary (reflexive) behavioral responses generated from the neuropathways, the vocal artist is empowered with an ability to maintain with ease: . Optimal performance, characterized by elite execution, coordination, and self-correction of the well-learned, highly automated, complex sensorimotor behavior of singing. An ideal performance state, characterized by heightened awareness, vigilant attention, and autonomic balance or "calm," absent of anxiety. Imagery, or mental manipulation of a mental representation of a sensory event, characterized by an ability to express one's thoughts and feelings as guided by an infinite supply of phenomenal images. A product of the imagination, imagery is a conscious and cognitive function of the working memory that, it would seem, cannot be delegated to automated behavior.

This book is an accessible collection of case study scenarios ideal for physiology and pharmacology revision for pharmacy, medical, biomedical science, clinical science and healthcare students. Clearly structured and organized by major organ system, the book emphasises ways in which key signs and symptoms of disease inform diagnosis and the choice of treatment, together with the relevant pharmacological mechanisms. Each chapter has a clinical focus and includes clear learning outcomes, key points and model answers with detailed explanations designed to enhance students' understanding of the physiology and pharmacology underpinning each case study scenario. 50 topics are covered and the cases presented include an extensive range of psychological, neurological, endocrine, cardiovascular, respiratory, renal, gastrointestinal and reproductive disorders, their symptoms, complications and usual treatment along with the actions and uses of some widely- used drugs.* An essential revision text designed to help students apply their theoretical knowledge to real-life cases* Realistic case studies focusing on commonly occurring conditions and diseases* Model answers throughout* Learning outcomes provided at the beginning of each chapter* Key learning points presented in the cases follow each model answer* Helps students to understand the relevance and clinical implications of the topics studied in physiology and pharmacology courses* Reinforces major concepts and definitions* Includes a glossary with a full list of drugs and disorders to support the text

Estrogens are a family of hormones that potently regulate reproductive, cardiovascular, bone, brain, and other physiology by altering gene expression. In this book, the authors present topical research in the study of the biochemistry, therapeutic uses and physiological effects of hormones. Topics include the physiological effects of oestrogen in fish and its application; estrogens in osteoarthritis and inflammation; estrogens as mediators of obesity-induced inflammation; the transcriptional effect of estrogens on gene expression; and the role of estrogens in regulating the gender disparity of hepatocellular carcinoma.

Non-steroidal anti-inflammatory drugs (NSAIDs) are among the most widely used drugs for the suppression of inflammation and pain. However, the therapeutic uses of NSAIDs are frequently limited by the significant negative side effects including ulceration, most notably in the gastrointestinal tract. This book examines alternative therapies to healing wounds such as negative pressure wound therapy; and the use of honey and biomaterials. The book also examines the implications of involvement of NSAID-activated gene 1 in ulceration and wound healing.

This book explores the role of endothelial progenitor cells (EPCs) in the context of regenerative medicine (RegMed). In particular, it reveals the value of RegMed as a new TM branch intended to improve the health and quality of life, by restoring, maintaining or enhancing tissue and functions of organs. The book is divided into three chapters, the first of which describes the relevance of translational medicine (TM) as a new research approach to counteract the imposing challengeof age-related diseases. Of the diverse RegMed approaches, particular attention is paid to stem/progenitor cell-based therapies, their benefits and shortcomings, as well as to the description of types of stem and progenitor cells considered for regenerative cell therapies, such as EPCs as emerging candidates for RegMed applications. In turn, the second chapter outlines the clinical relevance of EPCs as both potential predictors, diagnostic and prognostic biomarkers of age-related diseases and therapeutic agents,discussing their advantages, disadvantages, and conflicting data. Chapter three proposes a potential roadmap for revising the findings and creating a clearer picture of valid data, which can provide support for various important aspects, i.e.isolating and characterizing EPCs by establishing standardized criteria for EPC research, identifying appropriate sub-populations for cell therapy, timing, dosing, priming of cells,and defining delivery modes for different applications. The book concludes with an overview of innovative strategies that could improve the efficacy of cell therapy at all levels, including cell priming, bio-nanotechnology, and tissue engineering.

Biological rhythms time the ebb and flow of virtually every physiological process, and their mutual coordination guarantees the integrity of the organism over space and time. Aging leads to the disintegration of this coordination, as well as to changes in the amplitude and/or frequency of the underlying rhythms. The results of this are accelerated loss of health during aging, and in experimental model systems curtailed lifespan occurs. This book will examine the machinery that constitutes circadian systems and how they impact physiologic processes. It will also discuss how disturbances of circadian rhythms can lead to complex diseases associated with aging. Much of this treatment will focus on metabolism and genome stability. Importantly, the chapters in this book will encompass work in several different models, in addition to human. The book will conclude with a discussion of modeling approaches to biologic cycles and chronotherapy, for future research and translation.

Physiology of Sport and Exercise, Seventh Edition With Web Study Guide, continues its legacy as a top physiology textbook and favorite of instructors and students alike. Combining research with extensive visual aids, this resource offers a simple way for students to develop an understanding of the body's abilities to perform various types and intensities of exercise and sport, to adapt to stressful situations, and to improve its physiological capacities. Written by a team of distinguished researchers, all past presidents of the American College of Sports Medicine, this seventh edition has been updated based on the most recent position stands, standards, and guidelines in the field of sport and exercise physiology. Throughout the text, updated photos join with the superb illustrations and medical artwork to clarify difficult concepts and illustrate how the body performs. Digital components found in the web study guide now include 26 animations that offer a dynamic way to experience physiological concepts, and 66 audio clips that provide explanations of complex physiological processes to aid students' understanding of important illustrations in the text. Leaders in the field discuss recent developments and real-world applications in 27 video clips to help students connect theoretical and practical concepts. Corresponding icons throughout the text notify students when digital elements are available to complement the materials. In addition to the expanded digital components, Physiology of Sport and Exercise, Seventh Edition, features new and updated content based on the latest research in the field: Additional information on overtraining and exercise addiction Expanded content on fatigue and mobility in aging New sections on epigenetics, bioinformatics, and neuromuscular function New information on exercise genomics New Research Perspectives emphasizing emerging findings in the field, and a new Research Perspectives Finder to help students locate key content quickly Ease of reading has been the standout feature of this popular text. The seventh edition continues to offer comprehensive coverage of the complex relationship between human physiology and exercise while maintaining an engaging and student-friendly tone. Unique learning features paired with an accessible layout, including chapter-opening outlines and review boxes throughout each chapter, will help students focus on the major concepts addressed. Study questions and a list of key terms at the end of the chapter increase students' opportunities for recall and self-testing. A comprehensive glossary and lists of common abbreviations and conversions provide easy reference for students as they complete labs and assignments. To foster an enriched learning experience, both students and instructors can take advantage of the web-based ancillaries that accompany the text. In addition to animations, videos, and audio clips, the web study guide includes comprehension quizzes to provide immediate feedback to students on their knowledge retention as well as end-of-unit mastery checks that students can use for evaluating their progress. Instructors are provided with access to an instructor guide, test package, ready-to-use chapter quizzes, and a presentation package plus image bank. The presentation package includes PowerPoint slides with key points and content, which can be modified to suit a variety of class structures. An image bank features all of the graphics, artwork, and content photos from the text for easy insertion into tests, quizzes, handouts, and other course materials. Digital extras-composed of the animations, videos, and audio clips that students find in the web study guide-bolster comprehension of challenging concepts. Physiology of Sport and Exercise has been a pivotal textbook of the engaging field of exercise physiology. Through dynamic and interactive learning activities, easy-to-follow layouts, and research-oriented content enriched with visual supplements, students and instructors will find this an invaluable resource for their continued education.

In three Volumes this mini book series presents current knowledge and new perspectives on cartilage as a specialized yet versatile tissue. This third volume provides insight into current and future treatment strategies for repair of cartilage lesions. This book addresses Professors, researchers and PhD students who are interested in musculoskeletal and cartilage pathobiology and tissue-engineering.

The new edition of the hugely successful Ross and Wilson Anatomy & Physiology in Health and Illness continues to bring its readers the core essentials of human biology presented in a clear and straightforward manner. Fully updated throughout, the book now comes with enhanced learning features including helpful revision questions and an all new art programme to further clarify the explanations given in the text. The 13th edition retains its popular website, which contains a wide range of 'critical thinking' exercises as well as new animations, an audio-glossary, the unique Body Spectrum (c) online colouring and self-test program, and helpful weblinks. This book is ideal for students of nursing and allied health professions, biomedical and paramedical science, operating department practice, complementary therapy and massage therapy, as well as trainee Health Care Assistants and those studying A' level or BTEC (or equivalent) human biology. Ross and Wilson Anatomy & Physiology in Health and Illness will be of particular help to readers new to the subject area, those returning to study after a period of absence and for anyone whose first language is not English. Latest edition of the world's most popular textbook on basic human anatomy and physiology with over 1.5 million copies sold worldwide Clear, no nonsense writing style helps make learning easy Accompanying website contains animations, audio-glossary, case studies and other self-assessment material, the unique Body Spectrum (c) online colouring and self-test software, and helpful weblinks Includes basic pathology and pathophysiology of important diseases and disorders Contains helpful learning features such as Learning Outcomes boxes, colour coding and design icons together with a stunning illustration and photography collection Contains clear explanations of common prefixes, suffixes and roots, with helpful examples from the text, plus a glossary and an appendix of normal biological values. Particularly valuable for students who are completely new to the subject, or returning to study after a period of absence, and for anyone whose first language is not English All new illustration programme brings the book right up-to-date for today's student Helpful 'Spot Check' questions at the end of each topic to monitor progress Fully updated throughout with the latest information on common and/or life threatening diseases and disorders Review and Revise end-of-chapter exercises assist with reader understanding and recall Over 120 animations - many of them newly created - help clarify underlying scientific and physiological principles and make learning fun

Fully updated, revised and consolidated into one single volume, the fourth edition of Kinanthropometry and Exercise Physiology offers the best theoretically contextualised, practical resource for instructors and students available. Incorporating substantial sections on kinanthropometry, exercise physiology, energy systems and the application of science in health and high performance settings, the book covers the basics of measurement in exercise science through to advanced methods, and includes brand new chapters on: Pre-exercise screening and health risk stratification Functional movement assessment Point of care testing Anthropometry standards Anaerobic power and capacity History of exercise for health benefits Monitoring training loads in high-performance athletes Measuring game style in team sports Offering on-line access to newly developed exercise science measurement tools through the Exercise Science Toolkit - www.exercisesciencetoolkit.com - no other book offers such a complete resource, from the science of kinanthropometry and exercise physiology to their applications in health and performance, through practical, interactive learning. This book is an essential companion for students on any sport and exercise science-related degree programme and any instructor leading practical, laboratory-based classes.

This book will provide the reader with an overview of the essential meanings of key words in the physiology of various organ systems. This book is linked to a Question and Answer book on these organ systems that was published previously by Springer and will focus on cardiovascular, pulmonary and renal physiology. Each physiology system will be organized in to five different sections, covering the main areas of interest and each section will contain at least ten clear definitions of the main topics in this area. This book will present an easy reference guide for those just starting out in the area of physiology and for those who are interested in clear and succinct definitions of key terms.

DNA and RNA fractions have been isolated from whole blood, serum, plasma, the surface of blood cells, and urine from both healthy persons and patients. Specific fragments have been identified as being related to particular disorders, for example, diabetes, cancer, myocardial infarction, and stroke. The ability to isolate these fractions and assess their relationship to specific diseases makes early noninvasive diagnosis possible.

This volume reports on the most recent progress in this field, including chapters on developing protocols for nucleic acid extraction, determining the origin of the circulating nucleic acids, the capacity of these nucleic acids to enter cells and exhibit biological activity, isolating and testing fetal cells from maternal blood, and discussing the clinical implications of these discoveries and developing the techniques that will bring them into clinical application.

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This cytoarchitectonic atlas of the human cerebral cortex depicts the cellular structure of the human cortex, detailing the arrangement of neuronal cell bodies as well as the relationships between cytoarchitectonic boundaries and anatomical landmarks. Presentation in MNI Stereotaxic Space will enables the atlas to serves as a useful working tool for structural/functional neuroimagers attempting to identify the cytoarchitectonic area within which a functional activation or a structural change has occurred. An introductory section discusses the history and current state of cytoarchitectonic studies, and a separate chapter on methods is also provided. Mapping of the frontal lobe, parietal lobe, insula, temporal lobe, occipital lobe and white matter fascicule follows.
Architectonic areas presented on average MNI brain (rather than a single brain), so individual peculiarities of the surface morphology of any given brain are regularized, thus helping the reader to see the essence of the location of an area.

Features full-page high quality photomicrographs for each cytoarchitectonic area of the cortex, with supplementary zoom images of particular details.

Offers commentary on the relation of sulci and gyri to architectonic areas, which will be useful to those looking to identify the cortical area within which functional or structural changes happened

Contains section discussing white matter fasciculi that permit connectivity between the cytoarchitectonic areas

Commentary pages on relationship to nonhuman primate cortex (macaque monkey) enables links to be made to the primate species in which most of the experimental anatomical and physiological information has been and continues to be gathered.

Testosterone makes us stronger, happier, and smarter. It also makes us meaner, more violent and more selfish. A scientific look into the vast and unexpected influence testosterone has on our behavior, our society, and our bodies. The brain of every man-and every woman-is shaped by this tiny molecule from before birth: it propels our drive for exploration and risk, for competition and creation, and even our survival. The effects of testosterone permeate the traditions, philosophy, and literature of every known culture-without it, the world would be a drastically different place. Testosterone also has a role in humanity's darker side, contributing to violence, hubris, poverty, crime, and selfishness. Recent revelations of the science of testosterone show that high levels will deplete compassion and generosity, and even reduce the affection we show our children. In The Virility Paradox, internationally renowned oncologist and prostate cancer researcher Charles Ryan explores this complex chemical system responsible for a diverse spectrum of human behaviors and health in both men and women. Ryan taps his vast experience treating prostate cancer with testosterone-lowering therapy, observing that this often leads to profound changes in the patients' perspectives on their lives and relationships. Often, for the better. Ryan uses the journeys of these patients and others to illustrate the vast and sometimes unexpected influence testosterone has on human lives. Through the stories of real men and women, he also explores the connections between testosterone and conditions like dementia, autism, and cancer, as well as the biological underpinnings of sexual assault and the effects it has on everything from crime to investing to everyday choices we make. Integrating the molecular and the medical, sociology and storytelling, The Virility Paradox;offers a fascinating look at how one hormone has shaped history, and the connections between our biology, our behavior, and our best selves.

Biorhythms are the rhythms of life within us all. The book and wheel should help the reader to understand himself and others better.

Each cycle - physical, emotional and intellectual - begins on the day you are born and rises and falls in positive and negative phases throughout your life.

This book provides the latest information on cancer metastasis from the standpoint of inflammation, especially innate immune reactions caused by endogenous mediators but not exogenous pathogens, with ideas on how to understand the complicated mechanisms of metastasis as well as to interpret therapeutic targets. The book includes the topic of the emerging roles of endogenous TLR4 ligands whose functions are shared intriguingly by metastasis and auto-inflammatory diseases such as rheumatoid arthritis. For example, most cancer therapies established so far are effective initially. However, they eventually face the great obstacles of drug resistance, immune evasion, and metastatic progression. One of the endogenous TLR4 ligands is thought to contribute to all three processes. The most important features of the book are to explain a concept of homeostatic inflammation, disturbance of which in the lungs gives rise to the establishment of a pre-metastatic pulmonary microenvironment based on primary tumor-mediated hijacking of the innate immune defense system against respiratory infection. In addition, structure-based thinking is another important feature of this book. It is proposed that inflammation forms a functional triangle with angiogenesis and coagulation, in the center of which cancer is located. Given the proposal of precision medicine by President Obama in the United States in 2015 and the recent success of immune-modulator-based therapy, this book will appeal to researchers in a variety of fields with the title of the book connecting the worst disease (metastasis) and the most fundamental event (inflammation) that is common to many diseases.

Despite the continuous effort from the scientific community and the advancements in neonatal intensive care, hypoxic-ischaemic brain injury of term and near-term infants remains a significant problem throughout the world. After asphyxia, infants may suffer from long-term neurological sequelae, including death, cerebral palsy, learning difficulties, epilepsy and other significant cognitive, developmental and behavioural problems in 40% of survivors. This book discusses the risk factors, prevalence and neurological impacts of asphyxia.

Pathophysiology and Pharmacology in Nursing has been carefully designed to provide an integrated introduction to both the biology of disease and the therapeutic agents that are used to manage them. It covers the basics of pharmacology, the core pathological concepts of inflammation, infection and cancer, as well as a systems based consideration of the pathophysiology and relevant pharmacology of common disorders. New to the second edition: All content updated and mapped to the 2018 NMC standards Two new chapters on 'Mental health conditions' and 'Renal conditions. The ideal starting point for student nurses to develop a robust, integrated knowledge of human disease and pharmacology, enabling them to provide care that is based on up-to-date knowledge of this important subject.

For nearly 30 years, Principles of Medical Biochemistry has integrated medical biochemistry with molecular genetics, cell biology, and genetics to provide complete yet concise coverage that links biochemistry with clinical medicine. The 4th Edition of this award-winning text by Drs. Gerhard Meisenberg and William H. Simmons has been fully updated with new clinical examples, expanded coverage of recent changes in the field, and many new case studies online. A highly visual format helps readers retain complex information, and USMLE-style questions (in print and online) assist with exam preparation. Just the right amount of detail on biochemistry, cell biology, and genetics - in one easy-to-digest textbook. Full-color illustrations and tables throughout help students master challenging concepts more easily. Online case studies serve as a self-assessment and review tool before exams. Glossary of technical terms, both in print and online. Clinical Boxes and Clinical Content demonstrate the integration of basic sciences and clinical applications, helping readers make connections between the two. New clinical examples have been added throughout the text. Student Consult eBook version included with purchase. This enhanced eBook experience includes access -- on a variety of devices -- to the complete text, images, and references from the book.

A pioneering exploration of olfaction that upsets settled notions of how the brain translates sensory information. Decades of cognition research have shown that external stimuli "spark" neural patterns in particular regions of the brain. This has fostered a view of the brain as a space that we can map: here the brain responds to faces, there it perceives a sensation in your left hand. But it turns out that the sense of smell-only recently attracting broader attention in neuroscience-doesn't work this way. A. S. Barwich asks a deceptively simple question: What does the nose tell the brain, and how does the brain understand it? Barwich interviews experts in neuroscience, psychology, chemistry, and perfumery in an effort to understand the biological mechanics and myriad meanings of odors. She argues that it is time to stop recycling ideas based on the paradigm of vision for the olfactory system. Scents are often fickle and boundless in comparison with visual images, and they do not line up with well-defined neural regions. Although olfaction remains a puzzle, Barwich proposes that what we know suggests the brain acts not only like a map but also as a measuring device, one that senses and processes simple and complex odors. Accounting for the sense of smell upsets theories of perception philosophers have developed. In their place, Smellosophy articulates a new model for understanding how the brain represents sensory information.

Blood Science is a relatively new discipline which merges biochemistry, haematology, immunology, transfusion science and genetics. This bringing together of traditional disciplines requires a corresponding change in education and training for healthcare scientists and Blood Science: Principles and Pathology is written in response to this emerging need. An introduction to the subject and an overview of the techniques used in blood science are followed by a series of chapters based on groups of analytes investigated in blood - red blood cells, white blood cells and platelets, followed by the constituents of plasma, including waste products, electrolytes, glucose, lipids, enzymes, hormones, nutrients, drugs, poisons and others. Each chapter is supported by learning objectives, summaries and further information, and a focus is given to chapter specific case studies with interpretation to demonstrate how laboratory data in conjunction with clinical details is utilised when investigating patients with actual or suspected disease. Finally, a separate chapter offers more detailed case reports that integrate the different aspects of blood science. Undergraduate students taking blood science modules as part of their BSc programmes in Biomedical and Healthcare Sciences will appreciate the level of integration between clinical biochemistry and haematology. In addition, this book will provide suitable initial reading for those students embarking on blood science modules on MSc programmes and will be of value to new graduates entering the profession and starting their career in blood science departments by supplementing practice-based training with the required theoretical underpinning. This book is approved by the Institute of Biomedical Science and written by its expert writers, many of whom work on the Institute s advisory panels.