The leading text on human physiology for more than four decades-enhanced by all new video tutorials For more than four decades, Ganong's Review of Medical Physiology has been helping those in the medical field understand human and mammalian physiology. Applauded for its interesting and engagingly written style, Ganong's concisely covers every important topic without sacrificing depth or readability, and delivers more detailed, high-yield information per page than any other similar text or review. Thoroughly updated to reflect the latest research and developments in important areas such as chronic pain, reproductive physiology, and acid-base homeostasis, Ganong's Review of Medical Physiology, Twenty-Sixth Edition incorporates examples from clinical medicine to illustrate important physiologic concepts. Ganong's will prove valuable to students who need a concise review for the USMLE, or physicians who want to keep pace with the ever-changing world of medical physiology. *More than 600 full-color illustrations*Two types of review questions: end-of-chapter and board-style*NEW! Increased number of clinical cases and flow charts*NEW! Video tutorials from the author; high-yield Frequently Asked Question feature with detailed explanations; improved legends that eliminate the need to refer back to the text

This volume provides methods to study bone morphogenetic proteins (BMPs) and BMP modulators in cell culture, in both invertebrate and vertebrate animal models, and for therapeutic applications. Chapters guide the reader in the use of primary and immortalized cell lines, methodologies that exploit transcription and receptor mechanisms, newly developed animal models using nematodes, flies, amphioxus, frogs, zebrafish, and genetically engineered mice, and pre-clinical approaches to understanding BMP function in bone regeneration, heterotopic ossification, and cancers. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Bone Morphogenetic Proteins: Methods and Protocols aims to ensure successful results in the further study of this vital field.

The Retinoids: Biology, Biochemistry, and Disease provides an overview and synthesis of the retinoid molecules, from basic biology to mechanisms of diseases and therapy. Divided into five sections, the book covers retinoic acid signaling from biochemical, genetic, developmental, and clinical perspectives. The text is divided into five sections, the first of which examines vitamin A metabolic and enzymatic pathways. Focus then shifts to the role of retinoic acid signaling in development, and then to retinoids and physiological function. The book concludes with chapters on retinoids, disease and therapy. Comprehensive in scope and written by leading researchers in the field, The Retinoids: Biology, Biochemistry, and Disease will be an essential reference for biologists, biochemists, geneticists and developmental biologists, as well as for clinicians and pharmacists engaged in clinical research involving retinoids.

The book gives teachers a grounding in biomechanics so that they can easily use yoga and/or stretching with their students. Most yoga teacher schools provide only limited training in anatomy and biomechanics, and the study of the effect of mechanical forces on structure and function is often overlooked and/or misunderstood. Aesthetic cues (ie instructing students where to place their hands and feet in yoga asana) may not be biomechanically appropriate for everyone. Readers will learn to fit the pose to the student, rather than making the student fit the pose. This book: Highlights useful, evidence-based applications and examples of yoga and/or stretching. Provides insight into critical interpretation of research findings helping the reader to avoid clinical assumptions. Encourages variety in popular modern day asana, using yoga props and a keen eye, based on the understanding of how tissues adapt to applied loads. Educates yoga teachers to think beyond common scripted yoga education. Supports teachers to understand biomechanics, rather than simply memorizing anatomy, empowering them to make smart choices for instructing a variety of populations in both private and group class settings.

Drawing together the best of text, video and interactive material for the complete A&P learning resource for nurses. Effective, holistic nursing is impossible without a firm grasp of how the human body functions, but knowledge of the scientific theory on its own is not enough. Using the person-centred practice framework as a guiding principle, this book brings anatomy and physiology to life combining the best of print and online learning into one integrated package. Key features: Connects theory with nursing practice exploring the science from the perspective of a fictional family Supported by a rich array of video material including interactive figures, animations and mini-tutorials - perfect for visual learners Full of engaging activities designed to complement self-directed learning Written with the needs of nurses firmly in mind, focusing on the essential information Supported by a SAGE Edge website containing complete access to videos, animations, student revision material, action plans, downloadable figures, over 800 flashcards, and a bank of 170 online multiple choice questions for assessment use. More than just a book! Get 12 months FREE access to an interactive eBook* when you buy the paperback! (Print paperback version only, ISBN 9781473938465) *interactivity only available through Vitalsource eBook Each purchase includes 12 months access to an interactive eBook version which seamlessly blends the traditional textbook format with the best of online learning. Students can study when and how they want and make use of additional tools including search, highlighting, annotation note sharing and much more.

This book focuses on C-type lectin receptors, a newly emerging family of pattern-recognition receptors (PRRs) and a crucial part of the human innate immune system. Above all, the authors highlight these receptors' role in the recognition of pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs) - one of the first steps in responding to foreign and potentially dangerous structures in the human body. The respective chapters chiefly examine various C-type lectin receptors, their corresponding ligands, and signalling. In addition to offering immunologists and clinicians important insights from the latest research, they may also provide novel points of departure for future drug development.

Now in its second edition, this comprehensive handbook provides a state-of-the-art overview of recent advances in drug and non-drug therapies for obesity and diabetes. It also addresses major comorbidities, covering topics such as, cardiovascular diseases, renal and neuropsychiatric disorders, appetite control and micro RNAs. Special attention is also devoted to pediatric care, including the latest recommendations for therapy and prevention. Obesity and type 2 diabetes are among the top global health-care budget concerns worldwide and impact professional practice at all levels: in hospitals, clinics and physicians' offices alike. They prominently feature in headlines, and virtually no family, community or country is exempt from their protean, deleterious consequences. Furthermore, given the multiple intersections in their pathways, they often go hand in hand. The good news is that scientific advances in all fields, including genomics, metabolomics, lipidomics and microbiomics, are increasing our understanding of these two disease areas. At the same time, artificial intelligence, machine learning, mobile health and advanced implantable and external devices are rendering prevention and management more available, safe and cost-effective. In addition, bariatric and metabolic surgery has evolved from a niche specialty to an officially endorsed option for several modalities of obesity and diabetes. This book presents the latest lifestyle, pharmacological, surgical and non-surgical treatment options, including endoscopic intervention and cell therapy. Objectively reviewing natural and artificial sweeteners and critically examining issues such as public health initiatives, government mandated taxes for unhealthy foods and environmental planning, no stone is left unturned in gathering the latest practical information. As such, the book will appeal to seasoned specialists, as well as students and healthcare professionals in training.

Given the upsurge of interest in complementary therapies and treatments, medical researchers are gradually being pressured to reassess and expand existing knowledge about the structure and organization of the human body. But in spite of the advances in modern technology, there are vast areas of human physiological activity, which continue to remain undetectable. Such processes, indicates Rudolf Steiner, are connected to spiritual forces. In these revealing lectures Steiner concentrates on the relationship of such forces to the physical organs. In particular, he discusses the organs, which make up our digestive and respiratory systems; the significance of 'warmth' in the function of the blood and its effects upon the ego; and the evolutionary process implicit in the formation of the spinal column and brain. All are dealt with in a scientific manner that will appeal equally to doctors and therapists, as well as students of Steiner's spiritual philosophy. At the same time they are remarkably accessible to the general reader.

The International Sport Coaching Framework (Version 1.2) is an adaptable document that provides a common language and set of principles about coaching on which the worldwide sport community can agree. Created by the International Council for Coaching Excellence (ICCE), the Association of Summer Olympic International Federations (ASOIF) and Leeds Metropolitan University (LMU), the Framework represents a significant step toward establishing consensus on the * primary functions of a coach; * roles and responsibilities of a coach in athlete development; * qualifications, knowledge and core competences needed for coaching effectively; and * methods by which coaches are educated, developed and certified. The International Sport Coaching Framework incorporates feedback, research and best practices from around the world to provide sport federations, coaching organisations, international federations and educational institutions with considerations for designing, benchmarking and refining their coaching education and certification programmes. The result is a universal platform that facilitates the development of coaches and, ultimately, the enrichment of sport for all.

Succeed in your course and learn more about potential careers with ACSM's Introduction to Exercise Science, 3rd Edition. This proven book provides an engaging, up-to-date overview of exercise science and related areas, such as athletic training and sports medicine. In every chapter, the author illustrates the importance and clinical relevance of each topic in the curriculum and gives you an insider's view of the profession through fascinating interviews and online video profiles and fieldtrips. As an American College of Sports Medicine publication, this full-color resource offers the unsurpassed quality and excellence that has become synonymous with titles by the leading exercise science and sports medicine organization in the world. NEW! A brand-new chapter shows how research is conducted, provides an overview of research as a career pursuit, and explores the concept of evidence-base practice. Video fieldtrips take you into different real-world settings to learn about exercise science careers. UPDATED! Interviews and video profiles of rising stars in the exercise science profession and working healthcare professionals (a dietician, cardiologist, exercise physiologist, etc.) demonstrate the challenges and rewards of careers that begin with an exercise science degree. UPDATED! The "Future of Exercise Science" chapter now reflects the latest trends in the field. Features important updates related to the 10th edition of ACSM's Guidelines for Exercise Testing and Prescription . REVISED! The motor behavior chapter is now more meaningful, relevant, up-to-date, and understandable. Chapter objectives, key terms and definitions, chapter summaries, and Thinking Critically boxes help you master key concepts.

In this book, the authors present topical research in the study of the morphology, biomechanics and clinical implications of trabecular and cortical bone. Topics discussed include trabecular bone biomechanics and morphology; cortical bone as an enduring depot of bone-seeking contaminants and the evaluation of cortical bone resportion rate on the basis of a contaminant (90SR) measurement in humans; evaluation of apparent stress and strain at fracture of human trabecular bone under quasi-static compression load using micro-CT finite elements simulation; application of computational modelling to predict the effect of exercise on whole bone strength; advancements in cortical bone imaging; morphology of the pelvis (acetabulum) and femur; the release kinetics of bone morphogenetic proteins from demineralised cortical bone grafts; and preservation of cortical bone in oral and maxillofacial surgery procedures.

See how to achieve stronger starts, more explosive turns, and faster times "Swimming Anatomy" will show you how to improve your performance by increasing muscle strength and optimizing the efficiency of every stroke.

"Swimming Anatomy" includes 74 of the most effective swimming exercises, each with step-by-step descriptions and full-color anatomical illustrations highlighting the primary muscles in action.

"Swimming Anatomy" goes beyond exercises by placing you on the starting block, in the water, and into the throes of competition. Illustrations of the active muscles for starts, turns, and the four competitive strokes (freestyle, breaststroke, butterfly, and backstroke) show you how each exercise is fundamentally linked to swimming performance.

You'll also learn how exercises can be modified to target specific areas, improve your form in the water, and minimize common swimming injuries. Best of all, you'll learn how to put it all together to develop a training program based on your individual needs and goals.

Whether you are training for a 50-meter freestyle race or the open-water stage of a triathlon, "Swimming Anatomy" will ensure you enter the water prepared to achieve every performance goal.

The study of phenomena that occur during sleep has always aroused a great interest in various fields of human knowledge, both in religion and in philosophy, as well as in science. Hippocrates and Aristotle conducted different studies and observations on sleep and dreams, focusing on the changes that affect the state of consciousness between the waking and sleeping states. Freud even started from the observations and interpretation of dreams in the foundation of the psychoanalytic method. After the introduction of the electroencephalogram (EEG) by Hans Berger (1929), the beginning of modern sleep medicine began. Currently, the scientific literature in this field is very vast, gathering different aspects of many medical specialties, mainly including psychiatry, neurology, pneumology, cardiology, internal medicine, and others. Precisely because of this broad extension, it is not completely explorable by clinicians and is not always adequate for their needs.

Tried and true - build A&P confidence every step of the way! Here's the approach that makes A&P easier to master. A student-friendly writing style, superb art program, and learning opportunities in every chapter build a firm foundation in this must-know subject to ensure success. Flexible presentation of content makes the text suitable for any course. Precisely detailed, full-colour illustrations throughout make every concept clear. Highly detailed anatomy photographs and full-colour illustrations enhance visual learning. Clinical application boxes put theory into action. Extensive microbiology tables reinforce the text. Questions for every figure in the book encourage critical thinking and reinforce understanding of the image and the content. A wealth of pedagogical features promotes learning and include chapter outlines * student objectives * new and related clinical terminology (with pronunciations) * study outlines * review questions and "For Further Thought" discussion topics * and a comprehensive glossary. Pretests and post-tests for every chapter with print and email capabilities assess progress. Instructor resources: Ebook, classroom & lecture planning resources, previous edition resources. Includes testbank, active classroom instructor guide, PowerPoint slides, image bank Student resources: Ebook

Published by the American College of Sports Medicine, this new edition is essential for certification candidates and practicing Exercise Physiologists. As the official preparation book for the ACSM Certified Exercise Physiologist examination, the title will guide those seeking certification as they prepare to sit for the exam. For those already practicing, this evidence-based resource will aid in providing the most current, competent guidance to clients. Now fully aligned with the tenth edition of ACSM s Guidelines for Exercise Testing and Prescription, this second edition is reflective of the most current standards in the field.These updates include moving to the new pre-participation guidelines, which represent an important and significant change in the prescription of an exercise program. Incorporating ACSM's Exercise is Medicine global health initiative throughout this text prepares the EP-C to become uniquely qualified to work with medical professionals to ensure that all patients and clients are participating in a physical activity program. Organized around the scope of ACSM EP-C practice domains, ACSM's Resources for the Exercise Physiologist includes an introductory section focusing on understanding exercise, physical activity, and pre-exercise screening. Coverage of assessment and programming for both healthy and special populations and extensive content about behavior change allows the EP-C to provide program options for varying types of clients. Finally, this text covers the ethics, legal issues, and business of fitness management.

The perfect companion to McCance's Pathophysiology, Sixth Edition, this valuable study guide helps you master textbook content. This study guide is full of helpful study tools and in-depth reviews. 43 case scenarios provide real-world examples showing how you can apply and integrate knowledge. Answer key may be found in the back of the study guide, allowing you to check your answers and evaluate your progress. UPDATED! More than 2,650 questions include question types such as: Match these Definitions, Choose the Correct Words, Complete these Sentences, Categorize these Clinical Examples, Explain the Pictures, Describe the Difference, Teach these People about Pathophysiology, and many more. NEW! An interactive format is used for all questions, helping you to understand and master the content - not just memorize the key facts. NEW! Teach these People about Pathophysiology questions challenge you to answer questions that patients might ask in real-life practice. NEW! Nearly 70 illustrations from McCance and Huether's Pathophysiology textbook are used in selected question types.

The Biology and Therapeutic Application of Mesenchymal Cells comprehensively describes the cellular and molecular biology of mesenchymal stem cells and mesenchymal stromal cells, describing their therapeutic potential in a wide variety of preclinical models of human diseases and their mechanism of action in these preclinical models. Chapters also discuss the current status of the use of mesenchymal stem and stromal cells in clinical trials in a wide range of human diseases and disorders, for many of which there are limited, or no other, therapeutic avenues. Provides coverage on both the biology of mesenchymal stem cells and stromal cells, and their therapeutic applications Describes the therapeutic potential of mesenchymal stem and stromal cells in a wide variety of preclinical models of human diseases and their mechanism of action in these preclinical models Discusses the current status of mesenchymal stem and stromal cells in clinical trials in a wide range of human diseases and disorders, for many of which there are limited, or no other, therapeutic avenues Written and edited by leaders in the field The Biology and Therapeutic Application of Mesenchymal Cells is an invaluable resource for those studying stem cells, cell biology, genetics, gene or cell therapy, or regenerative medicine. About the Author Kerry Atkinson, MBBS MD DTM&H FRCP FRACP, is an Adjunct Professor at the University of Queensland Centre for Clinical Research in Brisbane, Australia, an Adjunct Professor in the Stem Cell Laboratories, Queensland University of Technology at the Translational Research Institute, Brisbane, Queensland, Australia and a Specialist in Internal Medicine at the Salisbury Medical Centre, Brisbane, Queensland, Australia.

This volume is based on presentations by world-renowned investigators who gathered at the 76th Cold Spring Harbor Symposium on Quantitative Biology. It reviews the latest advances in our understanding of metabolism and disease, including research on fat, exercise and rhythms; insulin resistance and sensitivity; lifespan, aging and cancer; regulation and dysregulation of metabolism; signaling and gene regulation; environment and sensing; metabolic reprogramming; clocks and intermediary metabolism; metabolism and cancer; and autophagy, timing and small RNAs.

The Springer Handbook of Odor is the definitive guide to all aspects related to the study of smell and their impact on human life. For the first time, this handbook aligns the senso-chemo-analytical characterization of everyday smells encountered by mankind, with the elucidation of perceptual, hedonic, behavioral and physiological responses of humans to such odors. From birth onwards we learn to interact with our environment using our sense of smell. Moreover, evolutionary processes have engendered a multi-faceted communication that is supported - even dominated - by olfaction. This compilation examines the responses of humans to odors at different stages of life, thereby building a foundation for a widely overseen area of research with broader ramifications for human life. The expert international authors and editor align aspects, concepts, methodologies and perspectives from a broad range of different disciplines related to the science of smell. These include chemistry, physiology, psychology, material sciences, technology but also disciplines related to linguistics, culture, art and design. This handbook, edited by an internationally renowned aroma scientist with the support of an outstanding team of over 60 authors, is an authoritative reference for researchers in the field of odors both in academia and in industry and is also a useful reference for newcomers to the area.

This concise, case-based text discusses the current state of the art for the diagnosis and management of metabolic bones diseases. Each chapter opens with a unique case presentation and utilizes a consistent format that includes relevant anatomy, physiology, and pathophysiology as well as examination, treatment approaches and clinical outcomes. Topics covered include osteoporosis, rickets and osteomalacia, hypoparathyroidism and pseudohypoparathyroidism, osteogenesis imperfecta, Paget's disease of bone, calcium and phosphorous disorders, hypophosphatasia, sclerotic bone disorders, fibrous and osteochondroplasia, and other malignancies of bone. Written and edited by experts in the field, Metabolic Bone Diseases is a valuable resource for practicing endocrinologists, rheumatologists and orthopedic surgeons, residents and fellows.

Comprehensive, and evidence-based, Foundations of Athletic Training, 6th Edition integrates basic medical concepts and related scientific information to help athletic trainers and students develop a strong foundation in athletic training best practices. Using a problem-solving approach to the prevention, recognition, assessment, management, and disposition of sports-related injuries and diseases, the text helps students learn to think like practitioners and is fully aligned with the BOC competencies. This 6th Edition has been updated throughout to reflect current best practices in the field and includes four new chapters, new and updated references, and a powerful suite of online learning resources that save instructors time and help students succeed.

Terms, principles, and applications. Clear and simple. The 6th Edition of this classic kinesiology text continues the tradition of presenting a very complicated topic in a clear, simple, and easy-to-understand manner. Bite-size sections and over 500 full-color illustrations show how various anatomical systems are connected and help you identify and see the connections between common pathologies associated with certain anatomical structures.

The Comparative Anatomy and Histology of the Cerebellum was first published in 1972. Minnesota Archive Editions uses digital technology to make long-unavailable books once again accessible, and are published unaltered from the original University of Minnesota Press editions.This is the third and final volume of the late Dr. Larsell's definitive work on the cerebellum, brought to completion for publication by Dr. Jansen. Two additional contributing authors for this volume are Enrico Mugnaini, M.D., and Helge K. Korneliussen, M.D.The first section of this volume deals with the morphology of the human cerebellum. The morphogenetic development, the fissure formation, and the differentiation of the cerebellar lobules are described in detail, and followed by a comprehensive account of the adult cerebellum, its lobes and lobules. It is shown that the ten major lobules which Dr. Larsell distinguished in other mammals are recognizable also in man.Chapters on the cerebellum connections include detailed accounts of all afferent and efferent cerebellar tracts. A subsequent chapter, by Drs. Jansen and Korneliussen, is devoted to the fundamental plan of cerebellar organization. The final chapters, by Dr. Mugnaini, deal with the histology and cytology of the cerebellar cortex. A comprehensive account is given of electron micrographs, a virtual atlas of the ultrastructure of the cerebellar cortex, illustrate the description.

With a strong focus on problem solving and clinical decision making, Fluid, Electrolyte, and Acid-Base Physiology is your comprehensive, go-to guide on the diagnosis and management of fluid, electrolytes, and acid-base disorders. This in-depth reference moves smoothly from basic physiology to practical clinical guidance, taking into account new discoveries; new understanding of fluid, acid-base, and electrolyte physiology; and new treatment options available to today's patients. An essential resource for nephrologists and emergency practitioners, this extensively revised edition helps you make the best management decisions based on the most current knowledge. Presents questions and explanations throughout that let you test your knowledge and hone your skills. High-yield margin notes and key point boxes make essential information easy to review. Numerous line drawings, diagnostic algorithms, and tables facilitate reference. Distinguished authors apply their extensive experience in research, clinical practice, and education to make theoretical and clinical knowledge easy to understand and apply. Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, images, and references from the book on a variety of devices. More patient-based problem solving illustrates how key principles of renal physiology, biochemistry, and metabolic regulation are applied in practice, challenging you to test your knowledge and hone your decision-making skills. Highlights updated clinical approaches to the diagnosis and management of fluid, electrolyte, and acid-base disorders based on current research and understanding. Integrative whole-body physiology provides a more comprehensive grasp of the pathophysiology of fluid, electrolyte, and acid-base disorders.