Microarrays is an invaluable laboratory manual for anyone conducting experiments in the field of molecular biology or medical biochemistry who needs to understand and use microarray technologies. These technologies are especially appropriate in genome analysis, diagnostics, and studies involving differential gene expression.
Providing straightforward explanations, the authors demonstrate proven methods for biochip application and an overview of presently available instruments, biochips, and software. Chapters cover the different requirements for DNA and protein chips, as well as spotters and scanners. The book also covers high throughput screening, patent research, and the minimum requirements for setting up or expanding a microarray laboratory.
- Covers microarray applications, technology, and execution
- Written in an approachable yet informative tone
- Includes more than 100 detailed figures and graphs
- Examines the history of microarrays and their future potential
- Defines key terms from related disciplines
- Contains a full chapter on the importance of database research and patents
- Describes how to develop or improve one's own microarray laboratory

Engineering Ethics is the application of philosophical and moral systems to the proper judgment and behavior by engineers in conducting their work, including the products and systems they design and the consulting services they provide. In light of the work environment that inspired the new Sarbanes/Oxley federal legislation on whistle-blowing protections, a clear understanding of Engineering Ethics is needed like never before.
Beginning with a concise overview of various approaches to engineering ethics, the real heart of the book will be some 13 detailed case studies, delving into the history behind each one, the official outcome and the real story behind what happened. Using a consistent format and organization for each one giving background, historical summary, news media effects, outcome and interpretation--these case histories will be used to clearly illustrate the ethics issues at play and what should or should not have been done by the engineers, scientists and managers involved in each instance.
* Covers importance and practical benefits of systematic ethical behavior in any engineering work environment.
* Only book to explain implications of the Sarbanes/Oxley "Whistle-Blowing" federal legislation
* 13 actual case histories, plus 10 additional "anonymous" case histories-in consistent format-will clearly demonstrate the relevance of ethics in the outcomes of each one
* Offers actual investigative reports, with evidentiary material, legal proceedings, outcome and follow-up analysis
* Appendix offers copies of the National Society of Professional Engineers Code of Ethics for Engineers and the Institute of Electrical and Electronic Engineers Code of Ethics"

The Psychology of Learning and Motivation publishes empirical and theoretical contributions in cognitive and experimental psychology, ranging from classical and instrumental conditioning to complex learning and problem solving. Volume 46 contains chapters on category learning, prototypes, prospective memory, event memory, memory models, and musical prosody.
*Discusses the concepts of category learning, prototypes, prospective memory, event memory, memory models, and musical prosody
*Volume 46 of the highly regarded Psychology of Learning and Motivation series
*An essential reference for researchers and academics in cognitive science

Volume 28 in the series of Side Effects of Drugs Annuals (http: //www.elsevier.com/locate/series/seda) continues to serve its primary goal: to provide clinicians and medical investigators with a reliable and critical yearly survey of new data and trends in the area of Adverse Drug Reactions and Interactions. An international team of specialists has reviewed new data and trends by selecting from the year's writing all that is truly new and informative, by critically interpreting it, and by pointing to whatever is unproven or misleading. The use of the book is enhanced by separate indexes, allowing the reader to access the text via drug name, adverse effect, or drug interaction.
The current annual includes an essay by the editor, Dr Jeffrey Aronson, entitled 'Classifying Drug Adverse Reactions in the 21st Century.' In it he describes how the modern approach to classifying adverse drug reactions takes into account the dose that causes the reaction, the time-course of the reaction, and the susceptibility factors that increase the individual patient's risk, and shows how this analysis can facilitate regulatory decision making.
*Provides a critical yearly survey of new data and trends
*Includes an essay that describes the modern approach to classifying adverse drug reactions
*Special reviews in this Annual include, among other topics: Antipsychotic drugs and now-onset diabetes mellitus, Treating asthma during pregnancy, and MMR vaccine and autism

For both experienced psychologists and graduate students, this book moves quickly through the essentials of WISC-IV interpretation and onto an insightful analysis of the major cognitive domains assessed by WISC-IV. It is the intention of the editors to raise the standard of practice from a simplistic 'test-label-place' model to a clinical model of assessing to understand and intervene. In the first chapter, the reader is presented with a comprehensive array of societal and home environment factors for which there is empirical evidence indicating their impact on the development of children s cognitive abilities, and ultimately their scores on intelligence tests. Subsequent chapters address issues related to the assessment of cognitive abilities that compose 'g', with special emphasis on the clinical correlates of working memory and processing speed from both neuropsychological and cognitive information processing perspectives. Each new chapter builds on material presented in previous chapters and progresses the reader purposefully through deeper levels of understanding of WISC-IV and cognitive assessment in general. Two chapters explicate the processing approach to interpretation that is the corner stone of the WISC-IV Integrated. A further chapter addresses the interpretation of WISC-IV findings within the context of other instruments as part of a full psychological evaluation. The final chapter provides an extensive case example of how to write psychological evaluation reports from a child-centered rather than a score-centered perspective that can have transforming impact on parents and teachers approach to the child. Overall, these four authors are the architects of a masterful new book on advanced WISC-IV interpretation from a clinical perspective, Together with the complimentary book, WISC-IV Clinical Assessment and Intervention, Second Edition these books provide the complete spectrum of information needed by all psychologists who use the WISC-IV in clinical practice.
* The Wechsler scale is the most widely used assessment of children's intelligence
* Authored by assessment experts including Harcourt Assessment staff with exclusive data on the WISC-IV
* Discusses interpretation of 4 index scores of WISC-IV
* Examines the WISC-IV in relation to other frequently used psychological tests
* Describes the importance of the WISC-IV integrated in clinical assessment
* Predicts scholastic achievement based on WISC-IV subtest scores
* Discusses modification of score interpretation based on culture, SES, & other contextual factors"

The book presents a basis for the interaction of the brain and nervous system with painting, music and literature, and a discussion of art from multiple facets such as anatomy, migraine, illusion and evolutionary biology. The book explores several aspects of the neurobiology of painting, including evolutionary neurobiology, sensation vs. perception, the visual brain and how the mind works, and also explores the affects of brain disorders and trauma on artist, with a concluding chapter on Frida Kahlo and the spinal cord injury that influenced her painting.

XML has become the lingua franca for representing business data, for exchanging information between business partners and applications, and for adding structure
and sometimes meaning to text-based documents. XML offers some special challenges and opportunities in the area of search: querying XML can produce very precise, fine-grained results, if you know how to express and execute those queries.
For software developers and systems architects: this book teaches the most useful approaches to querying XML documents and repositories. This book will also help managers and project leaders grasp how querying XML fits into the larger context of querying and XML. Querying XML provides a comprehensive background from fundamental concepts (What is XML?) to data models (the Infoset, PSVI, XQuery Data Model), to APIs (querying XML from SQL or Java) and more.
* Presents the concepts clearly, and demonstrates them with illustrations and examples; offers a thorough mastery of the subject area in a single book.
* Provides comprehensive coverage of XML query languages, and the concepts needed to understand them completely (such as the XQuery Data Model).
* Shows how to query XML documents and data using: XPath (the XML Path Language); XQuery, soon to be the new W3C Recommendation for querying XML; XQuery's companion XQueryX; and SQL, featuring the SQL/XML
* Includes an extensive set of XQuery, XPath, SQL, Java, and other examples, with links to downloadable code and data samples."

The best health practices are a synthesis of science and art. Surgery is a case in point. Although all competent surgeons follow scientific protocols, the best surgeons are masters of the art of surgery and produce better outcomes: e.g., smaller incisions; lower mortality rates. Psychotherapists are in exactly the same position. Psychotherapy is both a science and an art. There are excellent resources that convey information about empirically supported practices - the science of psychotherapy. However, this scientific information is incomplete in two important ways. It does not cover key matters that come up in psychotherapy (e.g., building a therapeutic relationship, resistance, termination), and it often does not fully cover the "art" of implementing these techniques, the nuances, the creative ways, the problem solving strategies when difficulties arise. This book is an attempt to have high profile, expert, "master" therapists discuss the art of handling these key issues.

The Handbook of the Psychology of Aging, 6e provides a comprehensive summary and evaluation of recent research on the psychological aspects of aging. The 22 chapters are organized into four divisions: Concepts, Theories, and Methods in the Psychology of Aging; Biological and Social Influences on Aging; Behavioral Processes and Aging; and Complex Behavioral Concepts and Processes in Aging.
The 6th edition of the "Handbook" is considerably changed from the previous edition. Half of the chapters are on new topics and the remaining half are on returning subjects that are entirely new presentations by different authors of new material. Some of the exciting new topics include Contributions of Cognitive Neuroscience to Understanding Behavior and Aging, Everyday Problem Solving and Decision Making, Autobiographical Memory, and Religion and Health Late in Life.
The "Handbook" will be of use to researchers and professional practitioners working with the aged. It is also suitable for use as a textbook for graduate and advanced undergraduate courses on the psychology of aging.
The Handbook of the Psychology of Aging, Sixth Edition is part of the Handbooks on Aging series, including Handbook of the Biology of Aging and Handbook of Aging and the Social Sciences, also in their 6th editions.

This Handbook provides a complete compendium of methods for evaluation of IT-based systems and solutions within healthcare. Emphasis is entirely on assessment of the IT-system within its organizational environment. The author provides a coherent and complete assessment of methods addressing interactions with and effects of technology at the organizational, psychological, and social levels.
It offers an explanation of the terminology and theoretical foundations underlying the methodological analysis presented here. The author carefully guides the reader through the process of identifying relevant methods corresponding to specific information needs and conditions for carrying out the evaluation study. The Handbook takes a critical view by focusing on assumptions for application, tacit built-in perspectives of the methods as well as their perils and pitfalls.
*Collects a number of evaluation methods of medical informatics
*Addresses metrics and measures
*Includes an extensive list of anotated references, case studies, and a list of useful Web sites

Every year, nearly one in five businesses suffers a major disruption to its data or voice networks or
communications systems. Since 9/11 it has become increasingly important for companies to implement a
plan for disaster recovery. This comprehensive book addresses the operational and day-to-day security
management requirements of business stability and disaster recovery planning specifically tailored for the needs and requirements of an Information Security Officer.
This book has been written by battle tested security consultants who have based all the material, processes and problem- solving on real-world planning and recovery events in enterprise environments world wide.
John has over 25 years experience in the IT and security sector. He is an often sought management consultant for large enterprise and is currently a member of the Federal Communication Commission's Homeland Security Network Reliability and Interoperability Council Focus Group on Cybersecurity, working in the Voice over Internet Protocol workgroup.
James has over 30 years experience in security operations and technology assessment as a corporate security executive and positions within the intelligence, DoD, and federal law enforcement communities. He has a Ph.D. in information systems specializing in information security and is a member of Upsilon Pi Epsilon (UPE), the International Honor Society for the Computing and Information Disciplines. He is currently an Independent Consultant.
.Provides critical strategies for maintaining basic business functions when and if systems are shut down
.Establishes up to date methods and techniques for maintaining second site back up and recovery
.Gives managers viable and efficient processes that meet new government rules for saving and protecting data in the event of disasters"

Volume 31 of the International Review of Research in Mental Retardation is a thematic exploration of personality and motivation in persons with mental retardation. Looking at a broad spectrum of intellectual disabilities, Mental Retardation, Personality, and Motivational Systems explores motivation as a moderator for performance and individualized effort. Coverage includes discussions of intrinsic and extrinsic motivation in both mentally retarded and non-retarded children, self-determination, interpersonal decision making in adolescents and adults with mental retardation, interpersonal relationships, and the connection between etiological-specific differences and motivation to form "behavioral phenotypes." A final chapter presents a transactional perspective on human ability, relying on constructs of intelligence, cognitive processes, and motivation, with implications for developmental interventions in the lives of persons with mental retardation.
*Explores personality and motivation in persons with mental retardation
*Discusses intrinsic and extrinsic motivation in both mentally retarded and non-retarded children
*A useful reference for researchers and scholars in developmental and cognitive psychology, as well as neuropsychology

In an embedded system, firmware is the software that directly interfaces with the microcontroller, controlling the system s function. The major forces driving the embedded firmware development process today are reduced development times, increased complexity, and the need to handle multiple tasks simultaneously. These forces translate into strenuous design requirements for embedded engineers and programmers. Many low-level embedded microcontroller designs have insufficient memory and/or architectural limitations that make the use of a real-time operating system impractical. The techniques presented in this book allow the design of robust multitasking firmware through the use of interleaved state machines. This book presents a complete overview of multitasking terminology and basic concepts. Practical criteria for task selection and state machine design are also discussed.
Designing multitasking firmware is arduous, complex and fraught with potential for errors, and there is no one, standard way to do it. This book will present a complete and well-organized design approach with examples and sample source code that designers can follow.
* Covers every aspect of design from the system level to the component level, including system timing, communicating with the hardware, integration and testing.
* Accompanying companion website contains the source code for the text examples and other useful design tools."

Atomic collisions offer some unique opportunities to study atomic structure and reaction mechanisms in experiment and theory, especially for projectiles of high atomic number provided by modern accelerators. The book is meant as an introduction into the field and provides some basic theoretical understanding of the atomic processes occurring when a projectile hits another atom. It also furnishes the tools for a mathematical description, however, without going deeper into the technical details, which can be found in the literature given. With this aim, the focus is on reactions, in which only a single active electron participates. Collisional excitation, ionization and charge transfer are discussed for collision velocities ranging from slow to comparable to the
speed of light. For the highest projectile velocities, energy can be converted into mass, so that electron-positron pairs are created. In addition to the systematic treatment, a theoretical section specializes on electron-electron
correlations and three chapters are devoted to selected highlights bordering to surface science and to physics with antiprotons.
* Simple access to the theory of collisions between ions and atoms
* Systematic treatment of basic features needed for an understanding
* Mathematical details are omitted and referred to references
* In order to bear out the essential ideas most clearly, a single active electron is assumed in most cases
* In selected examples, theoretical results are confronted with experiment
* Discussion supported by a large number of illustrations
* Selected highlights in borderline fields are presented

The study of catatonia in Autism Spectrum Disorders is a novel and controversial topic. Catatonia is a motor disorder characterized by stereotypy, rigidity, mutism, and posturing. These motor signs are also characteristic of autism. The interest in the relation between autism and catatonia stems from clinical observations that autistic and catatonic symptoms overlap, that some people with autism develop full-blown catatonia, and that anti-catatonic treatments bring relief in some of those patients.
This book explores the question of if the two syndromes have a common pathophysiology. It also examines whether the successful treatment of catatonia be applied to patients with both autism and catatonia. The book concludes with blueprints for the assessment, treatment, and future study of catatonia in Autism Spectrum Disorders. These blueprints aim to increase early recognition and treatment of catatonia in patients with autism, show the urgency of controlled treatment trials and increased collaborative and interdisciplinary research into the co-occurrence of these two enigmatic disorders.
* Provides a historical perspective of the concepts of catatonia and autism, as described by old European masters like Bleuler and Kalhbaum
* Presents clinical-epidemiological studies that apply systematic criteria of catatonia in populations with Autism Spectrum Disorders
* Includes a review of the importance of psychomotor function for normal and abnormal development

Solitons are waves that retain their form through obstacle and distance. Solitons can be found in hydrodynamics, nonlinear optics, plasma physics, and biology. Optical solitons are solitary light waves that hold their form over an expansive interval. Conservation of this form creates an effective model for long distance voice and data transmission.
The application of this principle is essential to the technology of wired communications. Optical solitons produce crystal clear phone calls cross-country and internationally. It is because of these that someone on the other end of the phone sounds 'in the next room.' It is also pertinent to high-speed network information transmittal.
Mollenauer and Gordon have written the only text that an engineer or graduate student will need to understand this foundation subject in optics.
*Written by Linn Mollenauer and James Gordon who are celebrated for applying optical solitons to telecommnications
*Combines mathematical developments with well-chosen practical examples and design formulas
*Extensive material on the basic physics of fiber optic transmission and its practical applications

Active matrix liquid crystal displays (AMLCDs) are the preferred choice when thin, low power, high quality, and lightweight flat panel displays are required. Here is the definitive guide to the theory and applications of AMLCDs.
Contemporary portable communication and computing devices need high image quality, light weight, thin, and low power flat panel displays. The answer to this need is the color active matrix liquid crystal display (AMLCD). The rides of AMLCD technology over less than two decades to undisputed dominance as a flat panel display has been breathtaking, and designers of portable devices need a thorough understanding of the theory and applications of AMLCDs. Willem den Boer, a holder of over 30 patents in imaging technologies, has created this guide to AMLCD theory, operating principles, addressing methods, driver circuits, application circuits, and alternate flat display technologies (including active matrix flat panel image sensors). Numerous design and applications examples illustrate key points and make them relevant to real-world engineering tasks.
Need more information on Mobile Displays, go to: http: //www.insightmedia.info/newsletters.php#mdr
-Systematically discusses the principles of liquid crystal displays and active matrix addressing.
-Describes methods of enhancing AMLCD image quality.
-Extensive coverage of AMLCD manufacturing techniques.
-Thorough examination of performance characteristics and specifications of AMLCDs.

A decade ago, the corporate world viewed grid computing as a curiosity. Today, it views it as an opportunity--a chance to reduce costs, improve performance, fund new projects, and take advantage of under-utilized capacity. The engineering behind this transformation has been amply documented. Until now, however, little has been written to prepare managers, executives, and other decision-makers to implement grid computing in a sensible and effective way.
Grid Computing: The Savvy Manager's Guide examines the technology from a rigorous business perspective, equipping you with the practical knowledge you need to assess your options and determine what grid computing approach is right for your enterprise. This book is heavy on real-world experience, distilling from a rich assortment of case studies the best practices currently at work in a variety of industries. Always attentive to grid computing s many competitive advantages, it is also realistic about the challenges of selling the idea to staff and making it a part of your company s culture.
Grid Computing has an Online Companion at www.savvygrid.com with contents, details, community forum, and latest updates for the material.
* Sketches the history of grid computing, showing how it made the leap from academia to business.
* Examines the criteria you'll need to meet to make your network "grid-enabled."
* Explains how a grid-based solution can be made to meet key organizational requirements, including security, scheduling, data storage, and fault-tolerance.
* Surveys the approaches currently available and helps you choose the one that will best meet your needs, both now and in the future.
* Focuses heavily on the competitive advantages you can reap from grid computing, and provides advice on convincing your organization to adopt grid computing and making a successful transition."

This book describes the structure-property-composition relationships for silicate glasses and melts of industrial and geological interest. From Antiquity to the 20th century, an introductory chapter presents this subject in a historical perspective. Basic concepts are then discussed in three chapters where attention is paid to the glass transition and its various consequences on melt and glass properties, to the structural and physical differences between amorphous and crystalline silicates, and to the mutual relationships between local order, energetics and physical properties.

With pure SiO2 as a starting point, compositions of increasing chemical complexity are successively dealt with in a dozen chapters. The effects of network-modifying cations on structure and properties are first exemplified by alkali and alkaline earth elements. The specific influence of aluminum, iron, titanium, and phosphorus are then reviewed. With water, volatiles in the system COHS, noble gases, and halogens, the effects of volatile components are also described. The last chapter explains how the results obtained on simpler melts can be applied to chemically complex systems. In each chapter, physical and chemical properties are described first and followed by a review of glass and melt structure. When possible, pressure effects are also considered.
*From SiO2 to complex silicate compositions, the physical and chemical properties of melts and glasses of geological and industrial interest
*Structural characterization of melts and glasses, from ambient to high pressure and temperature
*From basic concepts to an advanced level, a consistent description of the structure-property-composition relationships in glasses and melts

Given the vast amount of research related to behavioral assessment, it is difficult for clinicians to keep abreast of new developments. In recent years, there have been advances in assessment, case conceptualization, treatment planning, treatment strategies for specific disorders, and considerations of new ethical and legal issues. Keeping track of advances requires monitoring diverse resources limited to specific disorders, many of which are theoretical rather than practical, or that offer clinical advice without providing the evidence base for treatment recommendations. This handbook was created to fill this gap, summarizing critical information for adult behavioral assessment.
The Clinician s Handbook of Adult Behavioral Assessment provides a single source for understanding new developments in this field, cutting across strategies, techniques, and disorders. Assessment strategies are presented in context with the research behind those strategies, along with discussions of clinical utility, and how assessment and conceptualization fit in with treatment planning. The volume is organized in three sections, beginning with general issues, followed by evaluations of specific disorders and problems, and closing with special issues. To ensure cross chapter consistency in the coverage of disorders, these chapters are formatted to contain an introduction, assessment strategies, research basis, clinical utility, conceptualization and treatment planning, a case study, and summary. Special issue coverage includes computerized assessment, evaluating older adults, behavioral neuropsychology, ethical-legal issues, work-related issues, and value change in adults with acquired disabilities. Suitable for beginning and established clinicians in practice, this handbook will provide a ready reference toward effective adult behavioral assessment."

This book is a MUST for everyone in and around the optics community!
"Fiber Optic Essentials" provides professionals and students new to the field of fiber optics with a high-level knowledge of principles, theories and applications. This primer can also be used as a succinct overview of optics for those with some engineering and physics background. Individuals involved with optics in non-traditional capacities such as in marketing and legal departments will find this volume introduces basic concepts completely in an easy to read format.
Casimer and Carolyn DeCusatis have provided a concise resource with compact chapters and minimal equations conveying this complex topic in a straightforward and clear-cut style. Included in this book are chapters on fibers, cables, connectors, transmitters, modulators, noise, and optical link design. Concluding this reference are three indispensable appendices covering extensive definitions, acronyms (including initials and commonly used slang), measurement conversions and physical constants. This author team has produced a book that has truly shed light on this difficult subject.
* Comprehensively covers basic fiber optic 'facts'
* Explains how optics relate to everyday life
* Details fiber optic communication standards
* Chapter included on medical applications
* Timeline traces the history of optics with major milestones

Almost all branches of chemistry and material science now interface with organometallic chemistry - the study of compounds containing carbon-metal bonds. This widely acclaimed serial contains authoritative reviews that address all aspects of organometallic chemistry, a field which has expanded enormously since the publication of Volume 1 in 1964.
* Provides an authoritative, definitive review addressing all aspects of organometallic chemistry
* Useful to researchers within this active field and is a must for every modern library of chemistry
* High quality research book within this rapidly developing field

Given the vast amount of research related to behavioral assessment, it is difficult for clinicians to keep abreast of new developments. In recent years, there have been advances in assessment, case conceptualization, treatment planning, treatment strategies for specific disorders, and considerations of new ethical and legal issues. Keeping track of advances requires monitoring diverse resources limited to specific disorders, many of which give short shrift to child assessment, overlooking developmental considerations. Much of the existing literature is either theoretical/research in focus or clinical in nature. Nowhere are the various aspects of child behavioral assessment placed in a comprehensive research/clinical context, nor is there much integration as to conceptualization and treatment planning. The Clinician's Handbook of Child Behavioral Assessment was created to fill this gap, summarizing critical information for child behavioral assessment in a single source.
The Clinician's Handbook of Child Behavioral Assessment provides a single source for understanding new developments in this field, cutting across strategies, techniques, and disorders. Assessment strategies are presented in context with the research behind those strategies, along with discussions of clinical utility, and how assessment and conceptualization fit in with treatment planning. The volume is organized in three sections, beginning with general issues, followed by evaluations of specific disorders and problems, and closing with special issues. To ensure cross chapter consistency in the coverage of disorders, these chapters are formatted to contain an introduction, assessment strategies, research basis, clinical utility, conceptualization and treatment planning, a case study, and summary. Special issue coverage includes child abuse assessment, classroom assessment, behavioral neuropsychology, academic skills problems, and ethical-legal issues. Suitable for beginning and established clinicians in practice, this handbook will provide a ready reference toward effective child behavioral assessment.

This volume is mainly concerned with a systematic development of the theory of plasmas, the authority being firmly rooted in the pioneering work of Landau. Corresponding results are also given for partially ionized plasmas, relativistic plasmas, degenerate or non-ideal plasmas and solid state plasmas.

The aim of Advances in the Study of Behavior is to serve scientists engaged in the study of animal behavior, including psychologists, neuroscientists, biologists, ethologists, pharmacologists, endocrinologists, ecologists, and geneticists. Articles in the series present critical reviews of significant research programs with theoretical syntheses, reformulation of persistent problems, and/or highlighting new and exciting research concepts. Volume 35 is an eclectic volume that includes the mechanisms and evolution of arthropod and anuran communal sexual displays, a functional analysis of feeding, the sexual behavior and breeding system of tufted capuchin monkeys, acoustic communication in noise, ethics and behavioral biology, prenatal sensory ecology and experience, conflict and cooperation in chimpanzees, and the tradeoffs in the adaptive use of social and asocial learning.