Advances in Physical Organic Chemistry provides the chemical community with authoritative and critical assessments of the many aspects of physical organic chemistry. The field is a rapidly developing one, with results and methodologies finding application from biology to solid state physics.
* Reviews the application of quantitative and mathematical methods towards understanding chemical problems
* Covers organic, organometallic, bioorganic, enzymes and materials topics

A single volume of 85 articles, the Handbook of the Neurobiology of Aging is an authoritative selection of relevant chapters from the Encyclopedia of Neuroscience, the most comprehensive source of neuroscience information assembled to date (AP Oct 2008).
The study of neural aging is a central topic in neuroscience, neuropsychology and gerontology. Some well-known age-related neurological diseases include Parkinson's and Alzheimer's, but even more common are problems of aging which are not due to disease but to more subtle impairments in neurobiological systems, including impairments in vision, memory loss, muscle weakening, and loss of reproductive functions, changes in body weight, and sleeplessness. As the average age of our society increases, diseases of aging become more common and conditions associated with aging need more attention by doctors and researchers.
This book offers an overview of topics related to neurobiological impairments which are related to the aging brain and nervous system. Coverage ranges from animal models to human imaging, fundamentals of age-related neural changes and pathological neurodegeneration, and offers an overview of structural and functional changes at the molecular, systems, and cognitive levels. Key pathologies such as memory disorders, Alzheimer's, dementia, Down syndrome, Parkinson's, and stroke are discussed, as are cutting edge interventions such as cell replacement therapy and deep brain stimulation. There is no other current single-volume reference with such a comprehensive coverage and depth.
Authors selected are the internationally renowned experts for the particular topics on which they write, and the volume is richly illustrated with over 100 color figures. A collection of articles reviewing our fundamental knowledge of neural aging, the book provides an essential, affordable reference for scientists in all areas of Neuroscience, Neuropsychology and Gerontology.
* The most comprehensive source of up-to-date data on the neurobiology of aging, review articles cover: normal, sensory and cognitive aging; neuroendocrine, structural and molecular factors; and fully address both patholgy and intervention
* Chapters represent an authoritative selection of relevant material from the most comprehensive source of information about neuroscience ever assembled, (Encyclopedia of Neuroscience), synthesizing information otherwise
dispersed across a number of journal articles and book chapters, and saving researchers the time consuming process of finding and integrating this information themselves
* Offering outstanding scholarship, each chapter is written by an expert in the topic area and over 20% of chapters feature international contributors, (representing 11 countries)
* Provides more fully vetted expert knowledge than any existing work with broad appeal for the US, UK and Europe, accurately crediting the contributions to research in those regions
* Fully explores various pathologies associated with the aging brain (Alzheimer's, dementia, Parkinson's, memory disorders, stroke, Down's syndrome, etc.)
* Coverage of disorders and key interventions makes the volume relevant to clinicians as well as researchers
* Heavily illustrated with over 100 color figures

Delays in construction projects are frequently expensive, since there is usually a construction loan involved which charges interest, management staff dedicated to the project whose costs are time dependent, and ongoing inflation in wage and material prices. Many techniques are used to analyze delays. Some of these methods have inherent weaknesses and should be avoided. This book points out the shortcomings of these faulty methods and explains how a delay analysis should be performed. It then describes specifically how the analysis is done with CPM schedules. A explanation of delays and delay damages, presented in a straightforward, accessible manner, should be useful to public and private owners, construction managers, general contractors, subcontractors, designers, suppliers, and attorneys whose work involves them in the construction industry. The discussion will include subtleties of the process, such as shifts in the critical path, and non-critical delays. The subject of damages is covered in detail, including the major categories of extended field overhead and unabsorbed home office overhead. Likewise, the damages suffered by the owner, either actual or liquidated, are also explained. Finally, a chapter is devoted to managing the risk of delays and time extensions from the viewpoints of the various parties to a construction project. A discussion of early completion schedules and constructive acceleration is also included.
In this new ediion, all chapters are updated to reflect the changes in the construction field since the first edition published over l6 years ago. The 2nd edition includs over 40% more information such as new methods for analyzing delays with examples of the proper approach. The author also includes a new chapter on risk managment which focuses on the delay-related risks of the various parties in a construction project.
Explains the different categories of delays
Addresses the concept of concurrency and also non-critical delays
Discusses the more common approaches used for measuring and analyzing delays and the strengths and weaknesses associated with them
Prevention of Time-Related Delay Problems

Using the author's considerable experience of applying Mathcad to engineering problems, Essential Mathcad introduces the most powerful functions and features of the software and teaches how to apply these to create comprehensive calculations for any quantitative subject. The simple, step-by-step approach makes this book an ideal Mathcad text for professional engineers as well as engineering, science, and math students. Examples from a variety of fields demonstrate the power and utility of Mathcad's tools, while also demonstrating how other software, such as Excel spreadsheets, can be incorporated effectively.
*Many more applied examples and exercises from a wide variety of engineering, science, and math fields
* New: more thorough discussions of differential equations, 3D plotting, and curve fitting.
* A step-by-step approach enables easy learning for professionals and students alike

Sharon Johnson is the author of the best selling Therapist's Guide to Clinical Intervention now in its second edition. In this new book on PTSD, she lends her practical outline format to understanding PTSD assessment, treatment planning, and intervention. The book begins with a summary information on PTSD definition, and prevalence, assessment, and the evidence basis behind different treatment options. The book offers adjunctive skill building resources to supplement traditional therapy choices as well as forms for use in clinical practice.
This clinician's guide to diagnosing and treating PTSD is written in a concise format with much of the material in outline or bullet point format, allowing easy understanding of complex material for the busy therapist. The book includes a definition of the disorder, diagnostic criteria, the neurobiology of the disorder, tools and information for diagnosing clients, information on functional impairment, interventions, treatment planning, skill building, and additional clinician resources.
* Outlines treatment goals and objectives for DSM-IV PTSD diagnosis
* Discusses interventions and the evidence basis for each
* Offers skill building resources to supplement treatment
* Provides business and clinical forms for use with PTSD patients

This book is the definitive guide to the techniques and applications of position location, covering both terrestrial and satellite systems. It gives all the techniques, theoretical models, and algorithms that engineers need to improve their current location schemes and to develop future location algorithms and systems.

Comprehensive coverage is given to system design trade-offs, complexity issues, and the design of efficient positioning algorithms to enable the creation of high-performance location positioning systems. Traditional methods are also reexamined in the context of the challenges posed by reconfigurable and multihop networks. Applications discussed include wireless networks (WiFi, ZigBee, UMTS, and DVB networks), cognitive radio, sensor networks and multihop networks.

Features

Contains a complete guide to models, techniques, and applications of position location

Includes applications to wireless networks, demonstrating the relevance of location positioning to these "hot" areas in research and development

Covers system design trade-offs and the design of efficient positioning algorithms, enabling the creation of future location positioning systems

Provides a theoretical underpinning for understanding current position location algorithms, giving researchers a foundation to develop future algorithms

David Munoz is Director and Cesar Vargas is a member of the Center for Electronics and Telecommunications, Tecnologico de Monterrey, Mexico. Frantz Bouchereau is a senior communications software developer at The MathWorks Inc. in Natick, MA. Rogerio Enriquez-Caldera is at Instituto Nacional de Atrofisica, Optica y Electronica (INAOE), Puebla, Mexico.
Contains a complete guide to models, techniques and applications of position location
Includes applications to wireless networks (WiFi, ZigBee, DVB networks), cognitive radio, sensor networks and reconfigurable and multi-hop networks, demonstrating the relevance of location positioning to these hot areas in research and development
Covers system design trade-offs, and the design of efficient positioning algorithms enables the creation of future location positioning systems
Provides a theoretical underpinning for understanding current position location algorithms, giving researchers a foundation to develop future algorithms"

"Deploying QoS for IP Next Generation Networks: The Definitive Guide" provides network architects and planners with insight into the various aspects that drive QoS deployment for the various network types. It serves as a single source of reference for businesses that plan to deploy a QoS framework for voice, video, mobility and data applications creating a converged infrastructure. It further provides detailed design and implementation details for various service deployments across the various Cisco platforms such as the CRS-1, 12000, 7600 & 7200 series routers that are widely deployed in most Carrier Networks.
The book covers architectural and implementation specific information plus recommendations for almost all the popular line cards across the various hardware platforms widely used in the market. It also addresses QoS architecture and deployment on the Cisco CRS-1 platform and is considered as a unique selling point of this book.
In short the books serve as an "On the Job Manual" which can also be used as a study guide for Cisco specialist certification programs (CCNA, CCIP, CCIE)
This book will includes detailed illustration and configurations. In addition, it provides detailed case studies along with platform specific tests and measurement results. A link to a detailed tutorial on QoS metrics and associated test results will be available at the book's companion website in order to ensure that the reader is able to understand QoS functionality from a deployment standpoint.
Covers the requirements and solutions in deploying QoS for voice, video, IPTV, mobility and data traffic classes (Quad-play networks), saving the reader time in searching for hardware specific QoS information, given the abundance of Cisco platforms and line cards.Presents real-life deployments by means of detailed case studies, allowing the reader to apply the same solutions to situations in the work place.Provides QoS architecture and implementation details on Cisco CRS-1, 12000, 7600, and 7200 routing platforms using Cisco IOS/IOS-XR software, aiding the reader in using these devices and preparing for Cisco specialist certification.

Hyaluronan biology is being recognized as an important regulator of cancer progression. Paradoxically, both hyaluronan (HA) and hyaluronidases, the enzymes that eliminate HA, have also been correlated with cancer progression. Hyaluronan, a long-chain polymer of the extracellular matrix, opens up tissue spaces through which cancer cells move and metastasize. It also confers motility upon cells through interactions of cell-surface HA with the cytoskeleton. Embryonic cells in the process of movement and proliferation use the same strategy. It is an example of how cancer cells have commandeered normal cellular processes for their own survival and spread. There are also parallels between cancer and wound healing, cancer occasionally being defined as a wound that does not heal.
The growing body of literature regarding this topic has recently progressed from describing the association of hyaluronan and hyaluronidase expression associated with different cancers, to understanding the mechanisms that drive tumor cell activation, proliferation, drug resistance, etc. No one source, however, discusses hyaluronan synthesis and catabolism, as well as the factors that regulate the balance. This book offers a comprehensive summary and cutting-edge insight into Hyaluronan biology, the role of the HA receptors, the hyaluronidase enzymes that degrade HA, as well as HA synthesis enzymes and their relationship to cancer.
* Offers a comprehensive summary and cutting-edge insight into Hyaluronan biology, the role of the HA receptors, the hyaluronidase enzymes that degrade HA, as well as HA synthesis enzymes and their relationship to cancer
* Chapters are written by the leading international authorities on this subject, from laboratories that focus on the investigation of hyaluronan in cancer initiation, progression, and dissemination
* Focuses on understanding the mechanisms that drive tumor cell activation, proliferation, and drug resistance

The third edition of this long-serving successful reference work is a 'must-have' reference for anyone needing or desiring an understanding of the structure, chemistry, properties, production and uses of starches and their derivatives.

* Includes specific information on corn, wheat, potato, rice, and new chapters on rye, oat and barley (including waxy barley) starches

* Covers the isolation processes, properties, functionalities, and uses of the most commonly used starches.

* Explores the genetics, biochemistry, and physical structure of starches

* Presents current and emerging application trends for starch

This groundbreaking book covers every aspect of deadly toxic chemicals used as weapons of mass destruction and employed in conflicts, warfare and terrorism. Including findings from experimental as well as clinical studies, this one-of-a-kind handbook is prepared in a very user- friendly format that can easily be followed by students, teachers and researchers, as well as lay people. Stand-alone chapters on individual chemicals and major topics allow the reader to easily access required information without searching through the entire book.
This is the first book that offers in-depth coverage of individual toxicants, target organ toxicity, major incidents, toxic effects in humans, animals and wildlife, biosensors, biomarkers, on-site and laboratory analytical methods, decontamination and detoxification procedures, prophylactic, therapeutic and countermeasures, and the role of homeland security.
Presents a comprehensive look at all aspects of chemical warfare toxicology in one reference work. This saves researchers time in quickly accessing the very latest definitive details on toxicity of specific agents used in chemical warfare as opposed to searching through thousands of journal articles. Will include the most agent-specific information on the market.
Includes detailed coverage of the most exhaustive list of agents possibly used as chemical warfare agents in one source. Section 4: Agents That Can Be Used as Weapons of Mass Destruction ? 25 chapters long. Other books on the market only include a sample selection of specific agents. Offering all possible agents detailed under one cover makes this appealing to a wider audience and saves researchers time.

The Forward will be written by Dr. Tetsuo Satoh, Chiba University, Japan. He is one of the most respected, recognizable authorities on chemical warfare agents which will set the authoritative tone for the book.

Covers risk to humans, animals and the environment equally. Researchers involved in assessing the risks involved with a possible chemical warfare attack and those who are developing response plans to such attacks must look at not only the risks to human health but to our wildlife and environment as well. The holistic approach taken in this book ensures that the researchers have ready access to the details no matter which aspect of the effects of CWA's they might be concerned with.

In this book the author presents the state-of-the-art electromagnetic (EM)
theories and methods employed in EM geophysical exploration.
The book brings together the fundamental theory of EM fields and the practical
aspects of EM exploration for mineral and energy resources.
This text is unique in its breadth and completeness in providing an
overview of EM geophysical exploration technology.

The book is divided into four parts covering the foundations of EM
field theory and its applications, and emerging geophysical methods.
Part I is an introduction to the field theory required for baseline
understanding.
Part II is an overview of all the basic elements of
geophysical EM theory, from Maxwell's fundamental equations to modern
methods of modeling the EM field in complex 3-D geoelectrical formations.
Part III deals with the regularized solution of ill-posed
inverse electromagnetic problems, the multidimensional migration and imaging of
electromagnetic data, and general interpretation techniques.
Part IV describes major geophysical electromagnetic methods direct current (DC), induced polarization (IP), magnetotelluric
(MT), and controlled-source electromagnetic (CSEM) methods and covers
different applications of EM methods in exploration geophysics, including
minerals and HC exploration, environmental study, and crustal study.
* Presents theoretical and methodological findings, as well as examples of applications of recently developed algorithms and software in solving practical problems
* Describes the practical importance of electromagnetic data through enabling discussions on a construction of a closed technological cycle, processing, analysis and three-dimensional interpretation
* Updates current findings in the field, especially with MT, magnetovariational and seismo-electrical methods and the practice of 3D interpretations"

"Advances in Imaging and Electron Physics" merges two long-running serials--"Advances in Electronics and Electron Physics" and "Advances in Optical and Electron Microscopy." This series features extended articles on the physics of electron devices (especially semiconductor devices), particle optics at high and low energies, microlithography, image science and digital image processing, electromagnetic wave propagation, electron microscopy, and the computing methods used in all these domains.

This volume is aimed in general at scientists who have an interest in deciphering the molecular mechanisms for sequence recognition of DNA. The methods have general applicability to small molecules as well as oligomers and proteins, while the examples provide general principles involved in sequence recognition.

Catalysis is the acceleration of a chemical reaction by a catalyst, a substance that notably affects the rate of a chemical reaction without itself being consumed or altered. Since 1948, "Advances in Catalysis" has filled the gap between the papers that report on and the textbooks that teach in the diverse areas of catalysis research. The editors of and contributors to "Advances in Catalysis" are dedicated to recording progress in this area.
* Provides a comprehensive review of all aspects of catalytic research
* Contains in-depth, critical, state-of-the-art reports

New materials addressed for the first time include the chapters on minerals by Barber et al and the chapter on dislocations in colloidal crystals by Schall and Spaepen. Moriarty et al extend the first principles calculations of kink configurations in bcc metals to high pressures, including the use of flexible boundary conditions to model dilatational effects. Rabier et al clarify the issue of glide-shuffle slip systems in diamond cubic and related III-V compounds. Metadislocations, discussed by Feuerbacher and Heggen, represent a new type of defect in multicomponent metal compounds and alloys.
Kink mechanisms for dislocation motion at high pressure in bcc metals

Dislocation core structures identified in silicon at high stress

Metadislocations, a new type of defect, identified and described

Extension of dislocation concepts to complex minerals

First observations of dislocations in colloidal crystals

Written by an international panel of professional and academic peers, the book provides the engineer and technologist working in research, development and operations in the food industry with critical and readily accessible information on the art and science of infrared spectroscopy technology. The book should also serve as an essential reference source to undergraduate and postgraduate students and researchers in universities and research institutions.
Infrared (IR) Spectroscopy deals with the infrared part of the electromagnetic spectrum. It measure the absorption of different IR frequencies by a sample positioned in the path of an IR beam. Currently, infrared spectroscopy is one of the most common spectroscopic techniques used in the food industry. With the rapid development in infrared spectroscopic instrumentation software and hardware, the application of this technique has expanded into many areas of food research. It has become a powerful, fast, and non-destructive tool for food quality analysis and control.
Infrared Spectroscopy for Food Quality Analysis and Control reflects this rapid technology development. The book is divided into two parts. Part I addresses principles and instruments, including theory, data treatment techniques, and infrared spectroscopy instruments. Part II covers the application of IRS in quality analysis and control for various foods including meat and meat products, fish and related products, and others.

*Explores this rapidly developing, powerful and fast non-destructive tool for food quality analysis and control
*Presented in two Parts -- Principles and Instruments, including theory, data treatment techniques, and instruments, and Application in Quality Analysis and Control for various foods making it valuable for understanding and application
*Fills a need for a comprehensive resource on this area that includes coverage of NIR and MVA

"Advances in Imaging and Electron Physics" merges two long-running serials--"Advances in Electronics and Electron Physics" and "Advances in Optical and Electron Microscopy." This series features extended articles on the physics of electron devices (especially semiconductor devices), particle optics at high and low energies, microlithography, image science and digital image processing, electromagnetic wave propagation, electron microscopy, and the computing methods used in all these domains.
This monograph summarizes the authors' knowledge and experience acquired over many years in their work on computational charged particle optics. Its main message is that even in this era of powerful computers with a multitude of general-purpose and problem-oriented programs, asymptotic analysis based on perturbation theory remains one of the most effective tools to penetrate deeply into the essence of the problem in question.

Volume 3 of Biomembranes covers receptors of cell adhesion and cellular recognition. Proteins in the plasma membrane of cells are heavily involved in processes of cell adhesion, but such proteins were not actually isolated and characterized until the mid-1970s. Since then, application of the methods of molecular biology has led to the recognition of four major classes of cell adhesion molecule (CAMs), the immunoglobulin super family, the cadherins, the integrins, and the selecting. A convenient system in which to study the importance of cell adhesion is in blood platelets where aggregation eventually leads to thrombus formation in a process involving a range of surface glycoproteins. Interaction with the extracellular matrix is exemplified by CD44, the receptor for hyaluronan, and a complex carbohydrate that is a major component of the extracellular matrix surrounding migrating and proliferating cells. Membrane-associated mucins have a variety of effects on cell adhesion. The super family of immunoglobulin related proteins also include the T cell receptors and the major histocompatibility complex (MHC), which, together with the receptors for immunoglobulins (the Fc receptors), are of fundamental importance in the processes of immunity. Volume 3 of Biomembranes explores the structures and functions of the molecules involved in these important functions of the cell.

Peer-to-Peer (P2P) networks enable users to directly share digital content (such as audio, video, and text files) as well as real-time data (such as telephony traffic) with other users without depending on a central server. Although originally popularized by unlicensed online music services such as Napster, P2P networking has recently emerged as a viable multimillion dollar business model for the distribution of academic and clinical information, telecommunications, and social networking. Written at an accessible level for any reader familiar with fundamental Internet protocols, Peer-to-Peer Networking and Applications explains the conceptual operations and architecture underlying basic P2P systems using well-known commercial systems as models. The book also delineates the latest research directions, thereby providing not only a sophisticated understanding of current systems, but also the means to improve upon these systems with innovations that will better performance, security, and flexibility. Peer-to-Peer Networking and Applications is thus both a valuable starting point and an important reference to those practioners employed by any of the 200 companies with approximately $400 million invested in this new and lucrative technology.
* Uses well-known commercial P2P systems as models, thus demonstrating real-world applicability.
* Discusses how current research trends in wireless networking, high-def content, DRM, etc. will intersect with P2P, allowing readers to account for future developments in their designs.
* Provides online access to the Overlay Weaver P2P emulator, an open source tool that supports a number of peer-to-peer applications with which readers can practice.

Structural Analysis Rules of Thumb provides a comprehensive review of the classical methods of structural analysis and also the recent advances in computer applications. The prefect guide for the Professional Engineer's exam, Williams covers principles of structural analysis to advanced concepts. Methods of analysis are presented in a concise and direct manner and the different methods of approach to a problem are illustrated by specific examples. In addition, the book include the clear and concise approach to the subject and the focus on the most direct solution to a problem. Numerous worked examples are provided to consolidate the readers? understanding of the topics.
Structural Analysis Rules of Thumb is perfect for anyone who wishes to have handy reference filled with equations, calculations and modeling instructions as well as candidates studying for professional engineering registration examinations. It will also serve as a refresher course and reference manual for practicing engineers. Registered professional engineers and registered structural
Numerous worked examples are provided to consolidate the readers? understanding of the topics
Comprehensive coverage of the whole field of structural analysis
Supplementary problems are given at the end of each chapter with answers provided at the end of the book
Realistic situations encountered in practice and test the reader's ability to apply the concepts presented in the chapter
Classical methods of structural analysis and also the recent advances in computer applications

A unique and thorough investigation of the shift towards Europe-wide energy regulation, markets and business strategies, and the extent to which energy systems have become more liberalised over this period.
"Reshaping of European Gas and Electricity Industries" analyses the key issues facing the European energy industry, from a regulatory, market, and business perspective. Current challenges within the field are also reviewed, including competitive and environmental issues.
* Liberalization: Delivers timely insights into the changes facing the European energy industry in the face of deregulation.
* Competition: A direct look at business and marketing strategies in response to the influx of competition from across the globe.
* Environment: Provides powerful [insights] into the way environmentally-based legislation has now become a key driver of the energy industry in Europe

Genetic Diseases of the Kidney identifies and analyzes genetic abnormalities causing renal diseases in human subjects. Although in a sense the genome contains all the instructions required for the formation of a phenotype, the information is encoded in an extremely complicated fashion. In primary genetic diseases, the genetic instruction specifies a phenotype clearly linked with a discreet lesion confined to the kidney. However, the genetic disturbance may be imbedded in a complicated physiologic ensemble, so that the nexus between the genetic disturbance and the phenotype may be obscured; in consequence, the causal sequence is extremely difficult to unravel. In many instances the renal disease is one component of a complicated systemic hereditary disease, either monogenic or polygenic. Indeed, renal disease may arise as the sum of minor inputs from many different, seemingly unrelated genes, so that the genetic contributions may be difficult to identify. Confounding the problem further are environmental influences, originating either in the chromosomal environment from modifier genes, or in the extra-chromosomal environmental from intrauterine or postnatal influences. These considerations have determined both the organization of the text as well as the detailed description of the genetic disorders and the physiologic derangements that emerge.
* Lays the essential foundation of mammalian genetics principles for medical professionals with little to no background in genetics
* Analyzes specific renal diseases - both monogenic disorders confined to the kidney as well as systemic diseases with renal involvement - and explains their genetic causes.
*World-renowned editors andauthors offer expert frameworks for understanding the links between genes and complex clinical disorders (i.e., lupus, diabetes, HIV, and hypertension)

The Textbook of Nephro-Endocrinology is the definitive translational reference in the field of nephro-endocrinology, investigating both the endocrine functions of the kidneys and how the kidney acts as a target for hormones from other organ systems. It offers both researchers and clinicians expert, gold-standard analysis of nephro-endocrine research and translation into the treatment of diseases such as anemia, chronic kidney disease (CKD), rickets, osteoprosis, and, hypoparathyroidism.
* Investigates both the endocrine functions of the kidneys and how the kidney acts as a target for hormones from other organ systems.
* Presents a uniquely comprehensive and cross-disciplinary look at all aspects of nephro-endocrine disorders in one reference work.
* Clear translational presentations by the top endocrinologists and nephrologists in each specific hormone or functional/systems field.

This book focuses on the life and work of Nathan Zuntz (1847-1920), a German physiologist, who made significant contributions to high altitude physiology and aviation medicine.
He achieved fame for his invention of the Zuntz-Geppert respiratory apparatus in 1886 and the first treadmill (Laufband) in 1889. He also invented an X-ray apparatus to observe cardiac changes during exercise and constructed a climate chamber to study exercise under varying and sometimes extreme climates.
* Focuses on Zuntz's contribution to high altitude physiology and aviation medicine

"Annual Reports in Medicinal Chemistry" provides timely and critical reviews of important topics in medicinal chemistry together with an emphasis on emerging topics in the biological sciences, which are expected to provide the basis for entirely new future therapies.
* covers findings related to cardiovascular, inflammation, and pulmonary diseases
* examines issues in oncology, from mTor inhibitors to drug targets
* incorporates up-to-date information on drug design and discovery, including delivery to market