This comprehensive yet brief overview of the adolescent human brain discusses how the brain develops during this critical period of life and how that development impacts decision-making and risk-taking behavior in the adolescent.

This originated as a white paper requested by the Canadian government for a specific group looking to understand adolescent brain development in the context of adolescent behavior. The paper was not made available to the Canadian government outside of the specific task force that requested it nor to the general public. The authors have since decided that having put so much effort into concisely summarizing research on adolescent brain development, it would be a useful addition to researchers in psychology generally. The original paper has since been updated and revised considerably.

Gindis introduces AutoCAD with step by step instructions, stripping away complexities tobegin working in AutoCAD immediately. All concepts are explained first in theory, and then shown in practice, helping the reader understand "what "it is they are doing and why, before they do it.

Divided into three parts, the book covers beginning through advanced AutoCAD, including 3D features.

Also included is an extensive Appendix

for each part, detailing additional useful CAD-related information not often found

in other text books

The book contains supporting graphics (screen shots) and a summary with a self-test section at the end of each chapter. Also included are drawing examples and exercises, and tworunning projects that the student works on as he/she progresses through the chapters .

1) Strips away complexities, both real and perceived and reduces AutoCAD to easy-to-understand basic concepts.

2) Teaches only what is essential to operating AutoCAD first, thereby immediately building student confidence.

3) All basic commands are documented step-by-step, meaning that what the student needs to type in and how AutoCAD responds is all spelled out in discrete and clear steps with screen shots added as needed.

4) Using the author s extensive multi-industry knowledge of what is important and widely used in practice versus what is not, the material is presented by immediately immersing the student in practical, critically essential knowledge, with no padding of text or filler material.

5) All concepts are explained first in theory, and only then is AutoCAD introduced and the actual button pushing discussed. This is one of the key concepts in having students understand exactly what it is they are doing and why, before they do it."

Volume 14 of this series presents three interesting reviews of research on alkaloids. Chapter 1, by Paul L. Schiff, Jr., is a monumental effort, presenting a selective, comprehensive tabular review of research on the bisbenzylisoquinoline alkaloids, with an analysis of the respective alkaloid types. The chapter should serve as a very useful tool for the bench research scientist who is involved in the isolation and elucidation of structures of bisbenzylisoquinoline alkaloids. Moreover, the data in these tables provides the botanical distribution and occurrence (family, genus, species) of the various classes of these alkaloids. The alkaloids are also categorized by their molecular weights and structural types.
Chapter 2, by Toh-Seok Kam, is a review of alkaloids derived from Malaysian flora. Malaysia's position near the Equator confers on it a tropical climate characterized by high temperatures, humidity, and rainfall, conditions favorable for plant life that has resulted in a rich flora of about 15,000 species of higher plants. This review concentrates on work published during the past twenty years and where appropriate compares the occurrence of alkaloids with studies of similar plants from countries neighboring to Malaysia, especially Thailand and Indonesia.
Chapter 3, by Jie Jack Li, presents a collection of very interesting total syntheses of naturally occurring indole alkaloids where palladium chemistry plays a central role in the syntheses. Five different types of palladium-mediated reactions are treated: (1) oxidative cyclization reactions promoted by palladium (II) species; (2) transmetallation reactions with organoboranes, organostannanes, and organozinc reagents; (3)inter- and intramolecular Heck reactions; (4) reactions with &pgr; -allylpalladium as the intermediate; and (5) reactions using C-N bond formation as the key step for the synthesis.

"Annual Reports in Computational Chemistry" is a new periodical providing timely and critical reviews of important topics in computational chemistry as applied to all chemical disciplines. Topics covered include quantum chemistry, molecular mechanics, force fields, chemical education, and applications in academic and industrial settings. Each volume is organized into (thematic) sections with contributions written by experts. Focusing on the most recent literature and advances in the field, each article covers a specific topic of importance to computational chemists. "Annual Reports in Computational Chemistry" is a "must" for researchers and students wishing to stay up-to-date on current developments in computational chemistry.
* Broad coverage of computational chemistry and up-to-date information
* Topics covered include bioinformatics, drug discovery, protein NMR, simulation methodologies, and applications in academic and industrial settings
* Each chapter reviews the most recent literature on a specific topic of interest to computational chemists

Combining solid theoretical discussions with practical design examples, this book is an essential reference on developing RF and microwave switchmode power amplifiers. With this book you will be able to: Design high-efficiency RF and microwave power amplifiers on different types of bipolar and field-effect transistors using well-known and novel theoretical approaches, nonlinear simulation tools, and practical design techniques Design any type of high-efficiency switchmode power amplifiers operating in Class D or E at lower frequencies and in Class E or F and their subclasses at microwave frequencies, with specified output power Understand the theory and practical implementation of load-network design techniques based on lumped and transmission-line elements Combine multi-stage Doherty architecture and switchmode power amplifiers to significantly increase efficiency of the entire radio transmitter Learn the different types of predistortion linearization techniques required to improve the quality of signal transmission in a nonlinear amplifying system New to this edition: Comprehensive overview of different Doherty architectures which are, and will be used in modern communication systems to save power consumption and reduce costs A new chapter on analog and digital predistortion techniques Coverage of broadband Class-F power amplifiers, high-power inverse Class-F power amplifiers for WCDMA systems, broadband Class-E techniques

"Advances in Imaging and Electron Physics "merges two long-running serials--"Advances in Electronics and Electron Physics" and "Advances in Optical and Electron Microscopy."
This series features extended articles on the physics of electron devices (especially semiconductor devices), particle optics at high and low energies, microlithography, image science and digital image processing, electromagnetic wave propagation, electron microscopy, and the computing methods used in all these domains.
Key features:

* Contributions from leading authorities * Informs and updates on all the latest developments in the field

This volume of "Advances in Cell Aging and Gerontology" provides a timely review on the molecular and cellular basis of cardiovascular diseases (CVD). Age itself is the leading risk factor for cardiovascular diseases, which include loss of vasomotor function, athero- and arterio-sclerosis, hypertension, congestive heart failure and stroke. Together these pathologies comprise the leading causes of permanent disability, hospitalization and death for individuals over the age of 65. Thus, there is a critical need to assess both the age-associated causes leading to CVD as well as the current state of knowledge on preventive regimens designed to slow or modulate disease progression.

This book concisely summarizes the current knowledge related to the major aspects contributing to cardiovascular disfunction in the elderly as well as potential ways of maintaining or improving human cardiovascular healthspan.

This special volume of "Advances in Imaging and Electron Physics "details the current theory, experiments, and applications of neutron and x-ray optics and microscopy for an international readership across varying backgrounds and disciplines. Edited by Dr. Ted Cremer, these volumes attempt to provide rapid assimilation of the presented topics that include neutron and x-ray scatter, refraction, diffraction, and reflection and their potential application.
Key features:

* Contributions from leading authorities * Informs and updates on all the latest developments in the field

These papers survey the developments in General Topology and the applications of it which have taken place since the mid 1980s. The book may be regarded as an update of some of the papers in the Handbook of Set-Theoretic Topology (eds. Kunen/Vaughan, North-Holland, 1984), which gives an almost complete picture of the state of the art of Set Theoretic Topology before 1984. In the present volume several important developments are surveyed that surfaced in the period 1984-1991.

This volume may also be regarded as a partial update of Open Problems in Topology (eds. van Mill/Reed, North-Holland, 1990). Solutions to some of the original 1100 open problems are discussed and new problems are posed.

The Handbook of Mathematical Fluid Dynamics is a compendium of essays that provides a survey of the major topics in the subject. Each article traces developments, surveys the results of the past decade, discusses the current state of knowledge and presents major future directions and open problems. Extensive bibliographic material is provided. The book is intended to be useful both to experts in the field and to mathematicians and other scientists who wish to learn about or begin research in mathematical fluid dynamics. The Handbook illuminates an exciting subject that involves rigorous mathematical theory applied to an important physical problem, namely the motion of fluids.

Disturbing asbestos materials during construction is a serious hazard that all contractors may encounter. Because of the insidious nature of the material as a health hazard, EPA regulations require that even when a structure is to be completely demolished, asbestos (and all other hazardous materials) must be removed by a qualified contractor prior to general demolition. A construction contractor contemplating abatement work needs to ascertain regulatory applicability under one of the following: OSHA-approved state program, Federal OSHA regulations (applicable to the private sector and certain federal employees) or OSHA-approved.

Construction Worksite Compliance Guide to Asbestos provides the contractors, building owners and inspectors with the current best management practices for asbestos removal and disposal methods. Packed with checklist, tables and "quick lookup" materials, this manual provides a step by step approach for identifying asbestos, complying with OSHA and EPA regulations as well as the safe disposal of asbestos.

Ascertain the presence of asbestos through testing.

Prepare the abatement plan.

Submit the plan to the state, EPA or local municipality having jurisdiction.

Proper Waste Disposaltechinques

Scope of work. "

Digital Video and HD: Algorithms and Interfaces provides a one-stop shop for the theory and engineering of digital video systems. Equally accessible to video engineers and those working in computer graphics, Charles Poynton s revision to his classic text covers emergent compression systems, including H.264 and VP8/WebM, and augments detailed information on JPEG, DVC, and MPEG-2 systems. This edition also introduces the technical aspects of file-based workflows and outlines the emerging domain of metadata, placing it in the context of digital video processing.
With the help of hundreds of high quality technical illustrations, this book presents the following topics:
* Basic concepts of digitization, sampling, quantization, gamma, and filtering
* Principles of color science as applied to image capture and display
* Scanning and coding of SDTV and HDTV
* Video color coding: luma, chroma (4:2:2 component video, 4"f"SC composite video)
* Analog NTSC and PAL
* Studio systems and interfaces
* Compression technology, including M-JPEG and MPEG-2
* Broadcast standards and consumer video equipment"

Leading authors review the state-of-the-art in their field of investigation, and provide their views and perspectives for future research
Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered
All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist
Leading authors review the state-of-the-art in their field of investigation, and provide their views and perspectives for future research
Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered
All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist

Packed with case studies and practical real-world examples, Electricity Marginal Cost Pricing Principles allows regulators, engineers and energy economists to choose the pricing model that best fits their individual market.

Written by an author with 13 years of practical experience, the book begins with a clear and rigorous explanation of the theory of efficient pricing and how it impacts investor-owned, publicly-owned, and cooperatively-owned utilities using tried and true methods such as multiple-output, functional form, and multiproduct cost models. The author then moves on to include self-contained chapters on applying estimating cost models, including a cubic cost specification and policy implications while supplying actual data and examples to allow regulators, energy economists, and engineers to get "a feel" for the methods with which efficient prices are derived in today s challenging electricity market. The book is accompanied by a companion website which will allow for the testing of methods and validating results.

A guideto cost issues surrounding the generation, transmission, and distribution of electricity

Clearly explains cost models which can yield the marginal cost of supplying electricity to end-users

Real-world examples that are practical, meaningful, and easy to understand

Explans the policy implications of each example

Provide suggestions to aid in the formation of the optimal market price"

The Nuts and Bolts of Proofs: An Introduction to Mathematical Proofs provides basic logic of mathematical proofs and shows how mathematical proofs work. It offers techniques for both reading and writing proofs. The second chapter of the book discusses the techniques in proving if/then statements by contrapositive and proofing by contradiction. It also includes the negation statement, and/or. It examines various theorems, such as the if and only-if, or equivalence theorems, the existence theorems, and the uniqueness theorems. In addition, use of counter examples, mathematical induction, composite statements including multiple hypothesis and multiple conclusions, and equality of numbers are covered in this chapter. The book also provides mathematical topics for practicing proof techniques. Included here are the Cartesian products, indexed families, functions, and relations. The last chapter of the book provides review exercises on various topics. Undergraduate students in engineering and physical science will find this book invaluable.

This volume highlights recent developments in neuro-oncology that are not only increasing the survival rate of patients, but also improving their quality of life. Through an in-depth exploration of new therapies, including advanced diagnostic tools and a fresh perspective on molecular biology, immunology, and the clinical aspects of tumors, clinicians will gain a critical understanding of emerging therapies and techniques. Extensive coverage of tumor management and new therapeutic strategies, including gene therapy and molecularly targeted treatments are also explored, providing clinicians with new tools and tactics they can use to treat tumors of the nervous system.

Clinicians will find this handbook to be an invaluable resource for summarizing the present state of scientific and clinical knowledge in the field of neuro-oncology. In addition, practitioners in the field will uncover new tactics and therapies that will aid them in providing optimal neuro-oncological care for their patients.
* An invaluable resource that includes critical, in-depth insights into recent developments in neuro-oncology
* A fresh perspective on molecular biology, immunology, and other clinical aspects of tumors of the nervous system
* Extensive coverage of tumor management and new therapeutic strategies, including gene therapy and molecularly targeted treatments
* New tactics and therapies that will aid clinicians in their quest to provide optimal care for their neuro-oncological patients

Leading authors review the state-of-the-art in their field of investigation, and provide their views and perspectives for future research
Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered
All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist
Leading authors review the state-of-the-art in their field of investigation, and provide their views and perspectives for future research
Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered
All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist

Millions of homes built before 1978 contain lead paint, which poses a serious hazard to children under the age of 6. "Construction Worksite Compliance Guide" answers the most common questions about the requirements as mandated by the EPA's Renovate, Repair and Painting (RRP) rule and OSHA regulation 29CFR 1926.62. Packed with checklists, tables and "quick lookup" materials, this manual provides a step-by-step approach to determining job requirements and cost, assigning environmental responsibility to all parties, answering environmental questions, and conducting comprehensive worksite audits in the pre-bid phase of a renovation project.

This volume of Progress in Brain Research provides a synthetic source of information about state-of-the-art research that has important implications for the evolution of the brain and cognition in primates, including humans. This topic requires input from a variety of fields that are developing at an unprecedented pace: genetics, developmental neurobiology, comparative and functional neuroanatomy (at gross and microanatomical levels), quantitative neurobiology related to scaling factors that constrain brain organization and evolution, primate palaeontology (including paleoneurology), paleo-anthropology, comparative psychology, and behavioural evolutionary biology.

Written by internationally-renowned scientists, this timely volume will be of wide interest to students, scholars, science journalists, and a variety of experts who are interested in keeping track of the discoveries that are rapidly emerging about the evolution of the brain and cognition.

Written by internationally renowned scientists, this timely volume will be of wide interest to students, scholars, science journalists, and a variety of experts who are interested in keeping track of the discoveries that are rapidly emerging about the evolution of the brain and cognition.

Researchers in the field of exploration geophysics have developed new methods for the acquisition, processing and interpretation of gravity and magnetic data, based on detailed investigations of bore wells around the globe. "Fractal Models in Exploration Geophysics" describes fractal-based models for characterizing these complex subsurface geological structures.

The authors introduce the inverse problem using a fractal approach which they then develop with the implementation of a global optimization algorithm for seismic data: very fast simulated annealing (VFSA). This approach provides high-resolution inverse modeling results-particularly useful for reservoir characterization.

* Serves as a valuable resource for researchers studying the application of fractals in exploration, and for practitioners directly applying field data for geo-modeling * Discusses the basic principles and practical applications of time-lapse seismic reservoir monitoring technology-application rapidly advancing topic * Provides the fundamentals for those interested in reservoir geophysics and reservoir simulation study * Demonstrates an example of reservoir simulation for enhanced oil recovery using CO2 injection

This twenty-seventh volume of Research in Organizational Behavior carries forward the tradition of high-level scholarship on a broad array of organizational topics. Like many previous volumes, this collection is truly interdisciplinary, with chapters ranging from personality and decision making in organizations, to interpersonal dynamics such as helping and group process, to organizational-level analyses of legitimization and change. Each of the essays is well-reasoned, thoughtful, and provocative-- proving, once again, that the field of organizational behavior is flourishing in both its depth and scope. *Interdisciplinary with a wide range of subjects discussed by experts in their fields *Addresses personality development, empowerment, creativity, dysfunctional groups, institutionalization, and more

"Annual Reports in Medicinal Chemistry "provides timely and critical reviews of important topics in medicinal chemistry together with an emphasis on emerging topics in the biological sciences, which are expected to provide the basis for entirely new future therapies.

Optogenetics is a fast-growing field concerning the invention, and use, of molecules that are genetically expressed in cells, and then either report on cellular physiology in optical form, or enable control of specific pathways in cells when actuated by light. This book reviews the current state, as well as the underlying principles and future directions, of a diversity of optogenetic tools of importance for observing and controlling cellular signaling and physiology.

These tools are already revolutionizing neuroscience, and are starting to have impact on fields ranging from metabolism to development to cardiology. The book contains a dozen chapters written by world experts on these topics, half focusing on the optogenetic molecular tools themselves, and half on the genetic and hardware approaches that make them powerfully useful in intact tissues and organisms.
Leading authors review the state-of-the-art in their field of investigation and provide their views and perspectives for future researchChapters are extensively referenced to provide readers with a comprehensive list of resources on the topics coveredAll chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist

One of the most pressing questions in neuroscience, psychology and economics today is how does the brain generate preferences and make choices? With a unique interdisciplinary approach, this volume is among the first to explore the cognitive and neural mechanisms mediating the generation of the preferences that guide choice. From preferences determining mundane purchases, to social preferences influencing mating choice, through to moral decisions, the authors adopt diverse approaches to answer the question. Chapters explore the instability of preferences and thecommon neural processes that occur across preferences. Edited by one of the world s most renowned cognitive neuroscientists, each chapter is authored by an expert in the field, with a host of international contributors.
Emphasis on common process underlying preference generation makes material applicable to a variety of disciplines - neuroscience, psychology, economics, law, philosophy, etc.Offers specific focus on how preferences are generated to guide decision making, carefully examining one aspect of the broad field of neuroeconomics and complementing existing volumesFeatures outstanding, international scholarship, with chapters written by an expert in the topic area"

"Advances in Imaging and Electron Physics "merges two long-running serials--"Advances in Electronics and Electron Physics" and "Advances in Optical and Electron Microscopy."
This series features extended articles on the physics of electron devices (especially semiconductor devices), particle optics at high and low energies, microlithography, image science and digital image processing, electromagnetic wave propagation, electron microscopy, and the computing methods used in all these domains.
* Contributions from leading international scholars and industry experts
* Discusses hot topic areas and presents current and future research trends
* Invaluable reference and guide for physicists, engineers and mathematicians