"Advances in Imaging and Electron Physics " merges two long-running serials--"Advances in Electronics and Electron Physics" and "Advances in Optical and Electron Microscopy."
This series features extended articles on the physics of electron devices (especially semiconductor devices), particle optics at high and low energies, microlithography, image science and digital image processing, electromagnetic wave propagation, electron microscopy, and the computing methods used in all these domains.
* Contributions from leading international scholars and industry experts
* Discusses hot topic areas and presents current and future research trends
* Invaluable reference and guide for physicists, engineers and mathematicians

"Light and Skin Interactions" immerses you in one of the most fascinating application areas of computer graphics: appearance simulation. The book first illuminates the fundamental biophysical processes that affect skin appearance, and reviews seminal related works aimed at applications in life and health sciences. It then examines four exemplary modeling approaches as well as definitive algorithms that can be used to generate realistic images depicting skin appearance. An accompanying companion site also includes complete code and data sources for the BioSpec model, which is considered to be the most comprehensive first principles model in the field. Despite its wide scope of simulation approaches, the book s content is presented in a concise manner, focusing on relevant practical aspects. What s more, these approaches can be successfully applied to a wide range of additional materials, such as eye tissue, hair, and water.

Allows you to understand and predict the qualitative and quantitative behavior of complex natural systems.A general background on tissue optics clarifies several confusing conceptual issues, saving you valuable time in the early stages of researchIncludes complete code and data sources for the BioSpec model
"

Taking into account toxicity levels at normal consumption levels, intake per kg bodyweight and other acknowledged considerations, each chapter in this book will be based on one or more proven examples. It is intended to provide specific examples and potential improvements to the safety of the world's food supply, while also increasing the amount of food available to those in undernourished countries. This book is designed to to provide science-based tools for improving legislation and regulation.
Benefits:
* Reduce amount of food destroyed due to difference in regulations between nations
* Positively impact the time-to-market of new food products by recognizing benefit of "one rule that applies to all"
* Use the comparison of regulations and resulting consequences to make appropriate, fully-informed decisions
* Employ proven science to obtain global consensus for regulations
* Understand how to harmonize test protocols and analytical methods for accurate measurement and evaluation
* Take advantage of using a risk/benefit based approach rather than risk/avoidance to maximize regulatory decisions

Autodesk(r) Inventor(r) Simulation is an essential element in the Autodesk Digital Prototyping workflow that enables engineers, designers and manufacturers to transition from traditional design and physical prototyping methods to the innovative use of 3D modeling for evaluating form, fit and function. This allows virtual exploration and testing of objects, components and products before they are made, saving critical development time and cost. Autodesk Inventor Simulation provides the dynamic tools required to revolutionize the product design process, but these tools are complex to learn and use to their full potential.

Up and Running with Autodesk(r) Inventor(r) Simulation 2011 is dedicated to the requirements of Inventor users who need to quickly learn or refresh their skills and apply the dynamic simulation, stress analysis, frame analysis, and optimization capabilities of Inventor Simulation 2011. Providing clear guidance and all-important real-world tutorials, the step-by-step, heavily-illustrated approach of this book will help designers, engineers, and manufacturers of all skill levels become Simulation experts.
Get up to speed fast with real-life, step-by-step design problems-3 new to this edition Discover how to convert CAD models to working digital prototypes, enabling you to enhance designs and simulate real-world performance without creating physical prototypesLearn all about the frame analysis environment-new to Autodesk Inventor Simulation 2011-and other key features of this powerful software, including modal analysis, assembly stress analysis, parametric optimization analysis, effective joint creation, and moreManipulate and experiment with design solutions from the book using datasets provided on the book's companion website (http: //www.elsevierdirect.com/v2/companion.jsp?ISBN=9780123821027) and move seamlessly onto tackling your own design challenges with confidenceNew edition features enhanced coverage of key areas, including stress singularities, h-p convergence, curved elements, mechanism redundancies, FEA and simulation theory, with hand calculations, and more

"Advances in Imaging and Electron Physics " merges two long-running serials--"Advances in Electronics and Electron Physics" and "Advances in Optical and Electron Microscopy."
This series features extended articles on the physics of electron devices (especially semiconductor devices), particle optics at high and low energies, microlithography, image science and digital image processing, electromagnetic wave propagation, electron microscopy, and the computing methods used in all these domains.
* Contributions from leading international scholars and industry experts
* Discusses hot topic areas and presents current and future research trends
* Invaluable reference and guide for physicists, engineers and mathematicians

Since its inception in 1945, this serial has provided criticalarticles written by research specialists that integrate industrial, analytical, and technological aspects of biochemistry, organic chemistry, and instrumentation methodology in the study of carbohydrates.
Features contributions from leading authorities and industry experts Informs and updates on all the latest developments in the field
"

This edited textbook will be appropriate for use in advanced undergraduate and graduate level courses and will serve as a comprehensive and timely introduction to the field of adolescent development, providing students with a strong foundation for understanding the biological, cognitive and psychosocial transitions occurring during adolescence. While certain normative biological and cognitive processes are relevant for all youth, development varies dramatically based on a youth's position in society. The volume will focus on contextual factors such as culture, racial identity, socioeconomic position and sociopolitical and historical events, highlighting the impact such factors have on the physiological and psychological processes and treating them as key elements in understanding development during this life stage. The authors will cover the major theoretical positions (both historical and contemporary) about adolescence as well as the relevant research and application. Additionally, modern phenomena - the ever-increasing influence of pop culture (i.e. Hip Hop), mass media and technology (i.e., the internet, gaming) and the evolution of family, education and the church - will be explored in depth. Each chapter will be written by a known expert in the field.
* More extensive analysis of cultural, political and socioeconomic factors impacting development than competing texts
* Research-to-Practice section covers evidence-based research on practice implementation
*The only advanced text with ancillary support and pedagogy--instructor website with test bank and image collection, plus summary box and study questions in each chapter

FPGAs (Field-Programmable Gate Arrays) can be found in applications such as smart phones, mp3 players, medical imaging devices, and for aerospace and defense technology. FPGAs consist of logic blocks and programmable interconnects. This allows an engineer to start with a blank slate and program the FPGA for a specific task, for instance, digital signal processing, or a specific device, for example, a software-defined radio. Due to the short time to market and ability to reprogram to fix bugs without having to respin FPGAs are in increasingly high demand.
This book is for the engineer that has not yet had any experience with this electrifying and growing field. The complex issue of FPGA design is broken down into four distinct phases - Design / Synthesis / Simulation / Place & Route. Numerous step-by-step examples along with source code accompany the discussion. A brief primer of one of the popular FPGA and hardware languages, VHDL, is incorporated for a simple yet comprehensive learning tool. While a general technology background is assumed, no direct hardware development understanding is needed. Also, included are details on tool-set up, verifaction techniques, and test benches. Reference material consists of a quick reference guide, reserved words, and common VHDL/FPGA terms.
Learn how to design and develop FPGAs -- no prior experience necessary Breaks down the complex design and development of FPGAs into easy-to-learn building blocksContains examples, helpful tips, and step-by-step tutorials for synthesis, implementation, simulation, and programming phases

This streamlined "essential" version of the Molecular Pathology (2009) textbook extracts key information, illustrations and photographs from the main textbook in the same number and organization of chapters. It is aimed at teaching students in courses where the full textbook is not needed, but the concepts included are desirable (such as graduate students in allied health programs or undergraduates). It is also aimed at students who are enrolled in courses that primarily use a traditional pathology textbook, but need the complementary concepts of molecular pathology (such as medical students). Further, the textbook will be valuable for pathology residents and other postdoctoral fellows who desire to advance their understanding of molecular mechanisms of disease beyond what they learned in medical/graduate school.
Offers an essentialintroduction to molecular genetics and the "molecular" aspects of human diseaseTeaches from the perspective of "integrative systems biology," which encompasses the intersection of all molecular aspects of biology, as applied to understanding human diseaseIn-depth presentation of the principles and practice of molecular pathology: molecular pathogenesis, molecular mechanisms of disease, and how the molecular pathogenesis of disease parallels the evolution of the disease using histopathology. "Traditional" pathology section provides state-of-the-art information on the major forms of disease, their pathologies, and the molecular mechanisms that drive these diseases.Explains the practice of "molecular medicine" and the translational aspects of molecular pathology: molecular diagnostics, molecular assessment, and personalized medicineStudent web site hosts "self-assessment" questions; Professor web site hosts all figures from bookEach chapter ends with Key Summary Points and Suggested Readings

"

Treatise on Geophysics: Mineral Physics, Volume 2, provides a comprehensive review of the current state of understanding of mineral physics. Each chapter demonstrates the significant progress that has been made in the understanding of the physics and chemistry of minerals, and also highlights a number of issues which are still outstanding or that need further work to resolve current contradictions. The book first reviews the current status of our understanding of the nature of the deep Earth. These include the seismic properties of rocks and minerals; problems of the lower mantle and the core-mantle boundary; and the state of knowledge on mantle chemistry and the nature and evolution of the core. The discussions then turn to the theory underlying high-pressure, high-temperature physics, and the major experimental methods being developed to probe this parameter space. The remaining chapters explain the specific techniques for measuring elastic and acoustic properties, electronic and magnetic properties, and rheological properties; the nature and origin of anisotropy in the Earth; the properties of melt; and the magnetic and electrical properties of mantle phases.

"Readingsfrom the Treatise onGeochemistry" offers an interdisciplinary reference for scientists, researchers and upper undergraduate and graduate levelgeochemistry students that ismore affordable than the full Treatise. For professionals, this volume will provide anoverview of the field as a whole. For students, it will provide morein-depth introductory content thanis found inbroad-based geochemistry textbooks. Articleswere selected from chapters across all volumes of the full Treatise, and include: The Origin and Earliest History of the Earth, Compositional Evolution of the Mantle, Evolution of Sedimentary Rocks, Soil Formation, Geochemistry of Groundwater, Geologic History of Seawater, Hydrothermal Processes, and Biogeochemistry of Primary Production in the Sea.
Comprehensive, interdisciplinary and authoritative content selected by leading subject expertsRobust illustrations, figures and tablesAffordably priced sampling ofcontent from the full "Treatise on Geochemistry""

A single volume of 31 articles, Mechanisms of Hormone Actions on Behavior is an authoritative selection of relevant chapters from the Hormones Brain and Behavior 2e MRW, the most comprehensive source of neuroendocrinological information assembled to date (AP June 2009).
The study of hormones as they impact the brain and, subsequently, behavior is a central topic in neuroscience, endocrinology and psychiatry. This volume offers an overview of neuroendocrinological topics, approaching the subject from the perspective of the mechanisms which control hormone actions on behavior. Female, male and stress hormones are discussed at the cellular, behavioral and developmental level, and sexual differentiation of the development of hormone-dependent neuronal systems, neuropeptides/neuromodulators, and steroid-inducedneuroplasticity are addressed. There is simply no other current single-volume reference with such comprehensive coverage and depth.
Authors selected are the internationally renowned experts for the particular topics on which they write, and the volume is richly illustrated with over 175 figures (over 50 in color). A collection of articles reviewing our fundamental knowledge of the mechanisms of neuroendocrinology, the book provides an essential, affordable reference for researchers, clinicians and graduate students in the area.
- The most comprehensive single-volume source of up-to-date data on the mechanisms behind neuroendocrinology, with review articles covering x, y z
- Chapters synthesize information otherwise dispersed across a number of journal articles and book chapters, thus saving researchers the time consuming process of finding and integrating this information themselves
- Offering outstanding scholarship, each chapter is written by an expert in the topic area and approximately 35% of chapters are written by international contributors
- Provides more fully vetted expert knowledge than any existing work with broad appeal for the US, UK and Europe, accurately crediting the contributions to research in those regions
- Heavily illustrated with 175 figures, approximately 54 in color
- Presents material in most visually useful form for the reader

Modern embedded systems require high performance, low cost and low power consumption. Such systems typically consist of a heterogeneous collection of processors, specialized memory subsystems, and partially programmable or fixed-function components. This heterogeneity, coupled with issues such as hardware/software partitioning, mapping, scheduling, etc., leads to a large number of design possibilities, making performance debugging and validation of such systems a difficult problem.

Embedded systems are used to control safety critical applications such as flight control, automotive electronics and healthcare monitoring. Clearly, developing reliable software/systems for such applications is of utmost importance. This book describes a host of debugging and verification methods which can help to achieve this goal.
Covers the major abstraction levels of embedded systems design, starting from software analysis and micro-architectural modeling, to modeling of resource sharing and communication at the system levelIntegrates formal techniques of validation for hardware/software with debugging and validation of embedded system design flowsIncludes practical case studies to answer the questions: does a design meet its requirements, if not, then which parts of the system are responsible for the violation, and once they are identified, then how should the design be suitably modified?

Concise but comprehensive, "Structural Elements for Architects and Builders" is primarilyfocused onthe design and analysis of structural elements: columns, beams, tension members and their connections. The material is organized into a single, self-sufficient volume, including all necessary data for the preliminary design and analysis of these structural elements in wood, steel, and reinforced concrete.

Every chapter contains insights developed by the author and generally not found elsewhere. Additionally, the Appendices included at the end of the text contain numerous tables and graphs, based on material contained in industry publications, but reorganized and formatted especially for this text to improve clarity and simplicity, without sacrificing comprehensiveness.
Based on the standards and codes from For timber: The American Institute of Timber Construction's (AITC), The American Institute of Steel Construction's (AISC) The American Concrete Institute's (ACI) Building Code Requirements for Structural Concrete and Commentary (ACI 318 and ACI 318R)and the American Society of Civil Engineers
Contains graphs, charts, and tables to solve basic structural design problems
Step-by-step illustrative examples
Cover common connectors such as nails, bolts, and welds
"

"Annual Reports in Medicinal Chemistry "provides timely and critical reviews of important topics in medicinal chemistry together with an emphasis on emerging topics in the biological sciences, which are expected to provide the basis for entirely new future therapies.
* Covers findings related to cardiovascular, inflammation, and pulmonary diseases
* Examines issues in oncology, from mTor inhibitors to drug targets
* Incorporates up-to-date information on drug design and discovery, including delivery to market

Published since 1959, "International Review of Neurobiology" is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research.

With recent advancements in new knowledge, it has become evident that psychostimulants and related drugs of abuse are influencing our central nervous system (CNS) remarkably and could alter their function for a longtime. This volume is the first to focus on substance abuse induced brain pathology in the widest sense as it covers alterations in neuronal, glial and endothelial cell functions under the influence of acute or chronic usage of substance abuse.

This broad-ranging book equips programmers and designers with a thorough grounding in the techniques used to create truly network-enabled computer graphics and games. Written for graphics/game/VE developers and students, it assumes no prior knowledge of networking. The text offers a broad view of what types of different architectural patterns can be found in current systems, and readers will learn the tradeoffs in achieving system requirements on the Internet.

The book explains the foundations of networked graphics, then explores real systems in depth, and finally considers standards and extensions. Numerous case studies and examples with working code are featured throughout the text, covering groundbreaking academic research and military simulation systems, as well as industry-leading game designs.
Everything designers need to know when developing networked graphics and games is covered in one volume - no need to consult multiple sources.The many examples throughout the text feature real simulation code in C++ and Java that developers can use in their own design experiments.Case studies describing real-world systems show how requirements and constraints can be managed.

Since the publication of the first edition, the U.S. Surgeon General released the first-ever report on bone health and osteoporosis in October 2004. This report focuses even more attention on the devastating impact osteoporosis has on millions of lives. According to the National Osteoporosis Foundation, 2 million American men have osteoporosis, and another 12 million are at risk for this disease. Yet despite the large number of men affected, the lack of awareness by doctors and their patients puts men at a higher risk that the condition may go undiagnosed and untreated. It is estimated that one-fifth to one-third of all hip fractures occur in men.

This second edition brings on board John Bilezikian and Dirk Vanderschueren as editors with Eric Orwoll. The table of contents is more than doubling with 58 planned chapters. The format is larger - 8.5 x 11. This editionof Osteoporosis in Menbrings together even more eminent investigators and clinicians to interpret developments in this growing field, and describe state-of-the-art research as well as practical approaches to diagnosis, prevention and therapy.
Brings together more eminent investigators and clinicians to interpret developments in this growing field.

Describes state-of-the-art research as well as practical approaches to diagnosis, prevention and therapy.

There is no book on the market that covers osteoporosis in men as comprehensively as this book. "

Published since 1959, "International Review of Neurobiology" is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research.

This volume is a collection of articles covering "Novel Approaches to Studying Basal Ganglia and Related Neuropsychiatric Disorders. "Topics covered include molecular profiling of direct and indirect striatal medium spiny neurons, the role of epigenetics in development and function of basal ganglia and transgenic animal models for Parkinson's disease.

Research is increasingly showing the effects of family, school, and culture on the social, emotional and personality development of children. Much of this research concentrates on grade school and above, but the most profound effects may occur much earlier, in the 0-3 age range.This volume consists of focused articles from the authoritative Encyclopedia of Infant and Early Childhood Development that specifically address this topic andcollates research in this area in a way that isn't readily available in the existent literature, covering such areas as adoption, attachment, birth order, effects of day care, discipline and compliance, divorce, emotion regulation, family influences, preschool, routines, separation anxiety, shyness, socialization, effects of television, etc.This one volume referenceprovides an essential, affordable reference for researchers, graduate students and clinicians interested in social psychology and personality, as well as those involved with cultural psychology and developmental psychology.
Presents literature on influences of families, school, and culture in one sourcesaving userstime searching for relevant related topics in multiple places and literatures in order to fully understand any one areaFocused content on age 0-3- save time searching for and wading through lit on full age range for developmentally relevant info Concise, understandable, and authoritative for immediate applicability in research "

The biological function of clusterin (CLU, also known as ApoJ, SGP2, TRPM2, CLI) has been puzzling researchers since its discovery and characterization in the early 1980s. Approaches such as cloning, expression and functional characterization of the different protein products generated by the CLU gene have now produced a critical mass of information of tremendous biological importance that are teaching us an important lesson in molecular biology of gene expression regulation. This volume brings together the contributions of top researchers in the field, providing an overview and synthesis of the latest thought and findings relating to CLU.

Rajiv Kohli and Kash Mittal have brought together the work of experts from different industry sectors and backgrounds to provide a state-of-the-art survey and best practice guidance for scientists and engineers engaged in surface cleaning or handling the consequences of surface contamination.

Topics covered include: A systems analysis approach to contamination control Physical factors that influence the behavior of particle deposition in enclosures An overview of current yield models and description of advanced modelsTypes of strippable coatings, their properties and applications of these coatings for removal of surface contaminants In-depth coverage of ultrasonic cleaning Contamination and cleaning issues at the nanoscaleExperimental results illustrating the impact of model parameters on the removal of particle contamination

The expert contributions in this book provide a valuable source of information on the current status and recent developments in surface contamination and cleaning. The book will be of value to industry, government and academic personnel involved in research and development, manufacturing, process and quality control, and procurement specifications across sectors including microelectronics, aerospace, optics, xerography and joining (adhesive bonding).

ABOUT THE EDITORS

Rajiv Kohli is a leading expert with The Aerospace Corporation in contaminant particle behavior, surface cleaning, and contamination control. At the NASA Johnson Space Center in Houston, Texas, he provides technical support for contamination control related to ground-based and manned spaceflight hardware for the Space Shuttle, the International Space Station, and the new Constellation Program that is designed to meet the United States Vision for Space Exploration.

Kashmiri Lal "Kash" Mittal was associated with IBM from 1972 to 1994. Currently, he is teaching and consulting in the areas of surface contamination and cleaning, and in adhesion science and technology. He is the Editor-in-Chief of the Journal of Adhesion Science and Technology and is the editor of 98 published books, many of them dealing with surface contamination and cleaning.

"Also available"

Developments in Surface Contamination and Cleaning, Volume 1: Fundamentals and Applied Aspects (edited by Rajiv Kohli & K.L. Mittal). ISBN: 9780815515555.

. Provides guidance on best-practice cleaning techniques and the avoidance of surface contamination

. Covers contamination and cleaning issues at the nanoscale

. Includes an in-depth look at ultrasonic cleaning"

This fully revised 2e provides the only unified synthesis of available information concerning the mechanisms of higher-order memory formation. It spans the range from learning theory, to human and animal behavioral learning models, to cellular physiology and biochemistry. It is unique in its incorporation of chapters on memory disorders, tying in these clinically important syndromes with the basic science of synaptic plasticity and memory mechanisms. It also covers cutting-edge approaches such as the use of genetically engineered animals in studies of memory and memory diseases. Written in an engaging and easily readable style and extensively illustrated with many new, full-color figures to help explain key concepts, this book demystifies the complexities of memory and deepens the reader s understanding.
More than 25% new content, particularly expanding the scope to include new findings in translational research. Unique in its depth of coverage of molecular and cellular mechanisms Extensive cross-referencing to Comprehensive Learning and Memory Discusses clinically relevant memory disorders in the context of modern molecular research and includes numerous practical examples
"

The distinctive nature of the European pe/vc environment is on display in Stefano Caselli s presentation of its complete conceptual framework, from the volatile (its financial side) to the stable (its legal organization). A Bocconi University professor, Caselli offers a European perspective on market fundamentals, the v.c. cycle, and valuation issues, supporting his observations with recent examples and case studies. Written for investors, his book achieves many "firsts," such as clarifying many aspects of EU and UK financial institutions. Complete with finding aids, keywords, exercises, and an extensive glossary, Private Equity and Venture Capital in Europe is written not just for Europeans, but for everybody who needs to know about this growing market.
* Only book that provides a comprehensive treatment of PE/VC in UK/Europe, ideal for European business schools teaching professionals or pre-professionals who will work in Europe
* Provides a complete analysis of the EU versus US in all areas of PE/VC
* Contains cases and theory, providing both in one package
* Filled with pedagogical support features and online student and instructor resources"

This unique and much needed textbook will meet the rapidly emerging needs of programs training pharmacologic scientists seeking careers in basic research and drug discovery rather than such applied fields as pharmacy and medicine. While the market is crowded with many clinical and therapeutic pharmacology textbooks, the field of pharmacology is booming with the prospects of discovering new drugs, and virtually no extant textbook meets this need at the student level. The market is so bereft of such approaches that many pharmaceutical companies will adopt Hacker, et al. to help train new drug researchers.
The boom in pharmacology is driven by the recent decryption of the human genome and enormous progress in controlling genes and synthesizing proteins, making new and even custom drug design possible. This book makes use of these discoveries in presenting its topics, moving logically from drug receptors to the target molecules drug researchers seek, covering such modern topics along the way as side effects, drug resistance, Pharmacogenomics, and even nutriceuticals, one in a string of culminating chapters on the drug discovery process.
*Uses individual drugs to explain molecular actions
*Full color art program explains molecular and chemical concepts graphically
*Logical structure reflecting the current state of pharmacology and translational research, starting with receptors and finishing with target molecules
*Covers such intricacies as drug resistance and cell death
*Consistent format across chapters and pedagogical strategies make this textbook a superior learning tool