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Books > Academic & Education > Professional & Technical
The rapid and widespread acceptance of shared-memory multiprocessor
architectures has created a pressing demand for an efficient way to
program these systems. At the same time, developers of technical
and scientific applications in industry and in government
laboratories find they need to parallelize huge volumes of code in
a portable fashion. OpenMP, developed jointly by several parallel
computing vendors to address these issues, is an industry-wide
standard for programming shared-memory and distributed
shared-memory multiprocessors. It consists of a set of compiler
directives and library routines that extend FORTRAN, C, and C++
codes to express shared-memory parallelism.
"Parallel Programming in OpenMP" is the first book to teach both
the novice and expert parallel programmers how to program using
this new standard. The authors, who helped design and implement
OpenMP while at SGI, bring a depth and breadth to the book as
compiler writers, application developers, and performance
engineers.
* Designed so that expert parallel programmers can skip the opening
chapters, which introduce parallel programming to novices, and jump
right into the essentials of OpenMP.
* Presents all the basic OpenMP constructs in FORTRAN, C, and
C++.
* Emphasizes practical concepts to address the concerns of real
application developers.
* Includes high quality example programs that illustrate concepts
of parallel programming as well as all the constructs of
OpenMP.
* Serves as both an effective teaching text and a compact
reference.
* Includes end-of-chapter programming exercises.
This treatment guide is based on selected disorders taken from the
American Psychiatric Association DSM-IV Diagnostic Classifications.
The disorders selected are treatable or responsive to brief therapy
methods.
The therapist or student in training can use this book to identify
the elements needed for formulating a treatment plan on disorders
typically encountered in clinical practice. The approaches taken
are based on cognitive behavioral principles and makes use of
empirical findings. However, the case study format allows the
reader to see how the assessment and treatment is implemented in a
"real-life" patient, and not as a clinical abstraction distilled
from research studies. Moreover, the treatment plan is outlined in
a manner that makes reimbursement likely from managed care
organizations and insurance companies. Effective Brief Therapies is
useful as a reference for therapists and as a training guide for
graduate students.
Key Features
* Case Descriptions
* Treatment Conceptualization
* Assessment Techniques
* Treatment Implementation Techniques
* Concurrent Diagnoses and Treatment
* Complications and Treatment Implications
* Dealing with Managed Care and Accountability
* Outcome and Follow-up
* Dealing with Recidivism
"Difference Equations, Second Edition," presents a practical
introduction to this important field of solutions for engineering
and the physical sciences. Topic coverage includes numerical
analysis, numerical methods, differential equations, combinatorics
and discrete modeling. A hallmark of this revision is the diverse
application to many subfields of mathematics.
* Phase plane analysis for systems of two linear equations
* Use of equations of variation to approximate solutions
* Fundamental matrices and Floquet theory for periodic
systems
* LaSalle invariance theorem
* Additional applications: secant line method, Bison problem,
juvenile-adult population model, probability theory
* Appendix on the use of "Mathematica" for analyzing difference
equaitons
* Exponential generating functions
* Many new examples and exercises
Hope has previously been a construct more of interest to philosophy
and religion than in psychology. New research has shown, however,
that hope is closely related to optimism, feelings of control, and
motivation toward achieving one's goals. The Handbook of Hope
presents a comprehensive overview of the psychological inquiry into
hope, including its measurement, its development in children, how
its loss is associated with specific clinical disorders, and
therapeutic approaches that can help instill hope in those who have
lost theirs. A final section discusses hope in occupational
applications: how the use of hope can make one a better coach,
teacher, or parent.
Key Features
* Defines hope as a construct and describes development of hope
through the lifespan
* Provides multiple instruments for measuring hope
* Guides professionals in how to assess hope levels & implement
hope as part of therapy
* Relates hope to all portions of the population
* Includes case studies, figures, and tables to aid understanding
of research findings and concepts; discusses the importance of hope
to relationships, achieving goals, and success at work
Substance Use Disorders: Assessment and Treatment is a summary of
everything a therapist should know about substance abuse in one
easy-to-read comprehensive book. The book begins with a discussion
of the pharmacology of specific drug classes (opioids,
hallucinogens, etc.) and the epidemiology of abuse. It then
presents psychological theories of substance abuse, the initiation
and progression of substance abuse disorders, issues of prevention
and early intervention, and screening and assessment for substance
abuse (including specific tests for assessment) and discusses in
detail the various treatment methodologies available. Two final
chapters explore issues relevant to special populations and legal
and ethical considerations, regarding issues such as
confidentiality and coerced treatment.
Key Features
* A synthesis of the current research and clinical literature
* Includes strengths and weaknesses of commonly used psychometric
assessment measures
* Presentation and review of a complete Psychosocial/Substance Use
Assessment form
* Discussion of treatment settings and criteria for placement
decisions
* Discussion of treatment alternatives and effectiveness of major
pharmacological and psychotherapeutic approaches
* Discussion of factors leading to Relapse, and components of
Relapse Prevention programs
Physical Security 150 Things You Should Know is a comprehensive
reference for the security professional. This book covers all
aspects of security operations, from lighting and fencing to
tracking systems and crime risk management. The "150 Things"
offered by Tyska and Fennelly will help professionals in the field
build a well-trained, alert, and conscientious security staff.
Format is unique in that it identifies subjects, then discusses and
highlights specifics in terms of concerns and knowledge the
security professional requires
Quick and easy reference
Covers basics of physical security - both high and low tech
This volume emphasises studies related to
classical Stefan problems. The term "Stefan problem" is
generally used for heat transfer problems with
phase-changes such
as from the liquid to the solid. Stefan problems have some
characteristics that are typical of them, but certain
problems
arising in fields such as mathematical physics and
engineering
also exhibit characteristics similar to them. The term
classical" distinguishes the formulation of these problems
from
their weak formulation, in which the solution need not
possess
classical derivatives. Under suitable assumptions, a weak
solution
could be as good as a classical solution. In hyperbolic
Stefan
problems, the characteristic features of Stefan problems are
present but unlike in Stefan problems, discontinuous solutions
are
allowed because of the hyperbolic nature of the heat equation.
The
numerical solutions of inverse Stefan problems, and the analysis
of
direct Stefan problems are so integrated that it is difficult
to
discuss one without referring to the other. So no strict line
of
demarcation can be identified between a classical Stefan
problem
and other similar problems. On the other hand, including
every
related problem in the domain of classical Stefan problem
would
require several volumes for their description. A suitable
compromise has to be made.
The basic concepts, modelling, and analysis of the classical
Stefan problems have been extensively investigated and there
seems
to be a need to report the results at one place. This book
attempts to answer that need. Within the framework of the
classical Stefan problem with the emphasis on the basic concepts,
modelling and analysis, it tries to include some weak
solutions and analytical and numerical solutions also. The
main
considerations behind this are the continuity and the clarity
of
exposition. For example, the description of some phase-field
models in Chapter 4 arose out of this need for a smooth
transition
between topics. In the mathematical formulation of Stefan
problems, the curvature effects and the kinetic condition are
incorporated with the help of the modified Gibbs-Thomson
relation.
On the basis of some thermodynamical and metallurgical
considerations, the modified Gibbs-Thomson relation can be
derived, as has been done in the text, but the rigorous
mathematical justification comes from the fact that this
relation
can be obtained by taking appropriate limits of phase-field
models. Because of the unacceptability of some phase-field
models
due their so-called thermodynamical inconsistency, some
consistent
models have also been described. This completes the discussion
of
phase-field models in the present context.
Making this volume self-contained would require reporting and
deriving several results from tensor analysis, differential
geometry, non-equilibrium thermodynamics, physics and
functional
analysis. The text is enriched with appropriate
references so as not to enlarge the scope of the book. The
proofs
of propositions and theorems are often lengthy and different
from
one another. Presenting them in a condensed way may not be of
much
help to the reader. Therefore only the main features of
proofs
and a few results have been presented to suggest the
essential
flavour of the theme of investigation. However at each place,
appropriate references have been cited so that inquisitive
readers can follow them on their own.
Each chapter begins with basic concepts, objectives and the
directions in which the subject matter has grown. This is
followed
by reviews - in some cases quite detailed - of published works. In
a
work of this type, the author has to make a suitable
compromise
between length restrictions and understandability.
This volume of "Advances in Cell Aging and Gerontology" critically
reviews the rapidly advancing area of telomerase research with a
focus at the molecular and cellular levels. The clearly established
function of telomerase is to maintain chromosome ends during
successive rounds of cell division by adding a six base DNA repeat
on to the telomeric ends of chromosomes. As presented in the
chapters of this volume, the mechanisms that regulate telomerase
expression and activity are complex. Moreover, emerging data
suggest additional roles for telomerase in the regulation of cell
differentiation and survival.
It is expected that this quite comprehensive volume will provide a
valuable resource for graduate students and postdocs in the
telomerase field and for established investigators in other fields
who are beginning to study telomerase in their particular research
program. With an increasing number of proteins being brought into
the fold of telomerase research (e.g., DNA damage and repair
response proteins, heat-shock proteins, and proteins in various
signal transduction cascades) many new scientists are beginning to
study this enzyme from novel vantage points.
This book addresses public safety and security from a holistic and
visionary perspective. For the first time, safety and security
organizations, as well as their administration, are brought
together into an integrated work.
The protection of persons and property involves many public
agencies and priivate organizations. Entities from the criminal
jutics system (law enforcement, courts, corrections) as well as the
fire service, private security and hazardous materials all
contribute to public safety and security. This book addresses these
entities, as well as safety and security issues, from a holistic
and visionary perspective. It addresses criminal and non-criminal
safety and security concerns, provides an overview of each entity
(component) of the system of public safety and security, presents
an overview of the administration process involved in planning,
organizing, managing and evaluating public safety and security
organizations and describes collateral functions of investigations,
documentation and report writing.
Public safety and security organizations should not work in
isolation. Rather, they should collaborate to protect persons and
property. This book represents the first time all the public safety
and security entities have been addressed in one text.
Focuses on the theories, concepts, practices and problems related
to the present and future of public safety and security
Examines different strategies for problem solving which personnel
working in the field may utilize
Synthesizes college-level lectures prepared, presented, and updated
by the author over the past twenty years
This text aims to provide a survey of the state of knowledge in the
broad area that includes the theories and facts of economic growth
and economic fluctuations, as well as the consquences of monetary
and fiscal policies for general economic conditions.
Model Security Policies, Plans, and Procedures contains sample
security policy, planning, and procedural documents drawn from the
proven experiences of hundreds of America's most successful
corporations. If your job requires you to develop or update
security policies, plans, or procedures, this book will be a highly
valuable resource. The samples cover the key concepts of
organizational protection. Putting the samples to use, either as
presented or as drafting guides, can eliminate many hours of
tedious research and writing.
Offers a practical mode of reference for security
professionalsContains sample plans, policies and procedures
By covering the essential tips and techniques for investigators,
Investigations: 150 Things You Should Know becomes a useful
reference. By further covering the legal guidelines that
investigators must follow, it becomes indispensable. Through
anecdotes, case studies, and documented procedures the authors of
this book have amassed the most complete collection of
investigative information available.
This ready reference is for anyone interested in investigations.
Readers in and out of the law enforcement field will find this book
easy to use and understand when seeking explanations about a wide
variety of investigative topics including: constitutional law,
documentary evidence, interviewing and interrogating, and
surveillance.
Comprehensive overview of investigation
Easily readable and accessible information supplies all the
necessary elements for the beginner or expert investigator
Further investigative resources are listed in valuable appendices
This book provides a unified treatment of the characteristics of
telescopes of all types, both those whose performance is set by
geometrical aberrations and the effect of the atmosphere, and those
diffraction-limited telescopes designed for observations from above
the atmosphere. The emphasis throughout is on basic principles,
such as Fermat's principle, and their application to optical
systems specifically designed to image distant celestial
sources.
The book also contains thorough discussions of the principles
underlying all spectroscopic instrumentation, with special emphasis
on grating instruments used with telescopes. An introduction to
adaptive optics provides the needed background for further inquiry
into this rapidly developing area.
* Geometrical aberration theory based on Fermat's
principle
* Diffraction theory and transfer function approach to near-perfect
telescopes
* Thorough discussion of 2-mirror telescopes, including
misalignments
* Basic principles of spectrometry; grating and echelle
instruments
* Schmidt and other catadioptric telescopes
* Principles of adaptive optics
* Over 220 figures and nearly 90 summary tables
This widely-acclaimed serial contains authoritative reviews that
address all aspects of organometallic chemistry, a field which has
expanded enormously since the publication of Volume 1 in 1964.
Almost all branches of chemistry and material science now interface
with organometallic chemistry--the study of compounds containing
carbon-metal bonds. Organometallic compounds range from species
which are so reactive that they only have a transient existence at
ambient temperatures to species which are thermally very stable.
Organometallics are used extensively in the synthesis of useful
compounds on both large and small scales. Industrial processes
involving plastics, polymers, electronic materials, and
pharmaceuticals all depend on advancements in organometallic
chemistry.
During the past several years there has been a shortage of flight
opportunities for biological and medical projects. And those that
were available usually had severe restrictions on instrumentation,
number of subjects, duration, time allotted for performing the
experiments, a possibility for repetition of experiments. It is our
hope and expectation that this will change once the international
Space Station is in full operation. The advantages of a permanent
space station, already demonstrated by the Russian Mir station, are
continuous availability of expert crew and a wide range of
equipment, possibility of long-term experiments where this is
waranted, increased numbers of subjects through larger laboratory
space, proper controls in the large 1-G centrifuge, easier
repeatability of experiments when needed.
The limited number of flight opportunities during recent years
probably explains why it has taken so long to acquire a sufficient
number of high quality contributions for this seventh volume of
Advances in Space Biology and Medicine. While initially the series
wassailed at annually appearing volumes, we are now down to a
biannual appearance. Hopefully, it will be possible to return to
annual volumes in the future when results from space station
experimentation at beginning to pour in.
The first three chapters of this volume deal with muscle. Fejtek
and Wassersug provide a survey of all studies on muscle of rodents
flown in space, and include an interesting demography of this
aspect of space research. Riley reviews our current knowledge of
the effects of long-term spaceflight and re-entry on skeletal
muscle, and considers the questions still to be answered before we
can be satisfied that long-term space missions, such as on the
space station, can be safely undertaken. Stein reviews our
understanding of the nutritional and hormonal aspects of muscle
loss in spaceflight, and concludes that the protein loss in space
could be deleterious to health during flight and after return.
Strollo summarizes our understanding of the major endocrine systems
on the ground, then considers what we know about their functioning
in space, concluding that there is much to be learned about the
changes taking place during spaceflight. The many problems of
providing life support (oxygen regeneration and food supply) during
extended stay on the Moon, on Mars, or in space by means of plant
cultivation are discussed by Salisbury. The challenges of utilizing
electrophoresis in microgravity for the separation of cells and
proteins are illustrated and explained by Bauer and colleagues.
Finally, the chapter on teaching of space life sciences by Schmitt
shows that this field of science has come of age, but also that its
multidisciplinary character poses interesting challenges to
teaching it.
This book describes the risk management methodology as a specific
process, a theory, or a procedure for determining your assets,
vulnerabilities, and threats and how security professionals can
protect them.
Risk Management for Security Professionals is a practical handbook
for security managers who need to learn risk management skills. It
goes beyond the physical security realm to encompass all risks to
which a company may be exposed. Risk Management as presented in
this book has several goals:
Provides standardized common approach to risk management through a
framework that effectively links security strategies and related
costs to realistic threat assessment and risk levels
Offers flexible yet structured framework that can be applied to the
risk assessment and decision support process in support of your
business or organization
Increases awareness in terms of potential loss impacts, threats and
vulnerabilities to organizational assets
Ensures that various security recommendations are based on an
integrated assessment of loss impacts, threats, vulnerabilities and
resource constraints
Risk management is essentially a process methodology that will
provide a cost-benefit payback factor to senior management.
Provides a stand-alone guide to the risk management process
Helps security professionals learn the risk countermeasures and
their pros and cons
Addresses a systematic approach to logical decision-making about
the allocation of scarce security resources
Optically Stimulated Luminescence (OSL) has become the technique of
choice for many areas of radiation dosimetry. The technique is
finding widespread application in a variety of radiation dosimetry
fields, including personal monitoring, environmental monitoring,
retrospective dosimetry (including geological dating and accident
dosimetry), space dosimetry, and many more. In this book we have
attempted to synthesize the major advances in the field, covering
both fundamental understanding and the many applications. The
latter serve to demonstrate the success and popularity of OSL as a
dosimetry method.
The book is designed for researchers and radiation dosimetry
practitioners alike. It delves into the detailed theory of the
process from the point of view of stimulated relaxation phenomena,
describing the energy storage and release processes
phenomenologically and developing detailed mathematical
descriptions to enable a quantitative understanding of the observed
phenomena. The various stimulation modes (continuous wave, pulsed,
or linear modulation) are introduced and compared. The properties
of the most important synthetic OSL materials beginning with the
dominant carbon-doped Al2O3, and moving through discussions of
other, less-well studied but nevertheless important, or potentially
important, materials. The OSL properties of the two most important
natural OSL dosimetry material types, namely quartz and feldspars
are discussed in depth. The applications chapters deal with the use
of OSL in personal, environmental, medical and UV dosimetry,
geological dating and retrospective dosimetry (accident dosimetry
and dating). Finally the developments in instrumentation that have
occurred over the past decade or more are described.
The book will find use in those laboratories within academia,
national institutes and the private sector where research and
applications in radiation dosimetry using luminescence are being
conducted. Potential readers include personnel involved in
radiation protection practice and research, hospitals, nuclear
power stations, radiation clean-up and remediation, food
irradiation and materials processing, security monitoring,
geological and archaeological dating, luminescence studies of
minerals, etc.
Many controlled release veterinary drug delivery systems (CRVDDS)
are presently in use, and recently there has been a host of new
CRVDDS within veterinary medicine. The challenges of this area of
drug delivery arise from the unique anatomy and physiology of the
target animal, the cost constraints associated with the value of
the animal being treated and the extended periods of time that
delivery must be sustained for (often measured in months).
The purpose of this book is to introduce the reader to the unique
opportunities and challenges of the field of CRVDDS and to explain
and discuss the basic controlled release principles underlying the
development of CRVDDS. Its aim is to provide an overview of many of
the areas where CRVVDS have application, and to highlight the
opportunities and prospects for controlled release technology in
the veterinary field.
"Controlled Release Veterinary Drug Delivery" comprises chapters
that provide workers in the field (and those interested in this
area) with information on the design, development and assessment of
a variety of CRVDDS. The book contains chapters that describe the
relevant animal physiological and anatomical considerations
alongside descriptions of current and emerging controlled release
delivery systems for a variety of routes for drug delivery, and
present overviews on the physical and chemical assessment of
veterinary controlled release delivery systems.
The veterinary area is abound with opportunities for the
development of controlled release drug delivery technologies. It is
an area of medicine that is open to the acceptance of novel drug
delivery devices, and which readily encompasses the use of novel
routes of administration. It is an area of many unmet needs, most
of which offer opportunities and unique challenges for the
innovative formulation scientist to provide solutions. This book
will provide an insight into the biological, clinical and
pharmaceutical challenges that face the formulation scientist in
this interesting and diverse area of research.
Agenda Relevance is the first volume in the authors' omnibus
investigation of
the logic of practical reasoning, under the collective title, A
Practical Logic
of Cognitive Systems. In this highly original approach, practical
reasoning is
identified as reasoning performed with comparatively few cognitive
assets,
including resources such as information, time and computational
capacity. Unlike
what is proposed in optimization models of human cognition, a
practical reasoner
lacks perfect information, boundless time and unconstrained access
to
computational complexity. The practical reasoner is therefore
obliged to be a
cognitive economizer and to achieve his cognitive ends with
considerable
efficiency. Accordingly, the practical reasoner avails himself of
various
scarce-resource compensation strategies. He also possesses
neurocognitive
traits that abet him in his reasoning tasks. Prominent among these
is the
practical agent's striking (though not perfect) adeptness at
evading irrelevant
information and staying on task. On the approach taken here,
irrelevancies are
impediments to the attainment of cognitive ends. Thus, in its most
basic sense,
relevant information is cognitively helpful information.
Information can then be
said to be relevant for a practical reasoner to the extent that it
advances or
closes some cognitive agenda of his. The book explores this idea
with a
conceptual detail and nuance not seen the standard semantic,
probabilistic and
pragmatic approaches to relevance; but wherever possible, the
authors seek to
integrate alternative conceptions rather than reject them outright.
A further
attraction of the agenda-relevance approach is the extent to which
its principal
conceptual findings lend themselves to technically sophisticated
re-expression
in formal models that marshal the resources of time and action
logics and
label led deductive systems.
Agenda Relevance is necessary reading for researchers in logic,
belief
dynamics, computer science, AI, psychology and neuroscience,
linguistics,
argumentation theory, and legal reasoning and forensic science, and
will repay
study by graduate students and senior undergraduates in these same
fields.
Key features:
relevance
action and agendas
practical reasoning
belief dynamics
non-classical logics
labelled deductive systems
"
This book is an overview of ESIS Technical Committee 4's activities
since the mid-1980s. A wide range of tests is described and the
numerous authors is a reflection of the wide and enthusiastic
support we have had.
With the establishment of the Technical Committee 4, two major
areas were identified as appropriate for the activity. Firstly
there was an urgent need for standard, fracture mechanics based,
test methods to be designed for polymers and composites. A good
deal of academic work had been done, but the usefulness to industry
was limited by the lack of agreed standards. Secondly there was a
perceived need to explore the use of such data in the design of
plastic parts. Some modest efforts were made in early meetings to
explore this, but little progress was made. In contrast things
moved along briskly in the standards work and this has dominated
the activity for the last fourteen years. The design issue remains
a future goal.
Designers of high-speed integrated circuits face a bewildering
array of choices and too often spend frustrating days tweaking
gates to meet speed targets. "Logical Effort: Designing Fast CMOS
Circuits" makes high speed design easier and more methodical,
providing a simple and broadly applicable method for estimating the
delay resulting from factors such as topology, capacitance, and
gate sizes.
The brainchild of circuit and computer graphics pioneers Ivan
Sutherland and Bob Sproull, "logical effort" will change the way
you approach design challenges. This book begins by equipping you
with a sound understanding of the method's essential procedures and
concepts-so you can start using it immediately. Later chapters
explore the theory and finer points of the method and detail its
specialized applications.
* Explains the method and how to apply it in two practically
focused chapters.
* Improves circuit design intuition by teaching simple ways to
discern the consequences of topology and gate size decisions.
* Offers easy ways to choose the fastest circuit from among an
array of potential circuit designs.
* Reduces the time spent on tweaking and simulations-so you can
rapidly settle on a good design.
* Offers in-depth coverage of specialized areas of application for
logical effort: skewed or unbalanced gates, other circuit families
(including pseudo-NMOS and domino), wide structures such as
decoders, and irregularly forking circuits.
* Presents a complete derivation of the method-so you see how and
why it works.
Novel asymmetric synthetic methods are a vital strategem in the
armoury of the organic chemist, particularly for those involved in
the preparation or application of chiral organic molecules. this
series is devoted to presenting the latest advances in the field of
asymmetric synthesis, drawing contributions on emerging areas and
articles providing authoritative perspectives on more developed
synthetic stategies from leading researchers in the field. This
volume consists of six contributions on a variety of topical areas,
ranging from the preparation and application of chiral
cylopentadienes, the synthesis of non-racemic amines, diketones and
-keto esters and ferrocenes, to the use of biocatalysis and
application of microbial methods for the synthesis of chiral
molecules and fine chemicals.
Volume 11 of this series presents five timely reviews on current
research on alkaloids. Chapter 1 by Paul L. Schiff, Jr. is a
monumental survey of research that has been carried out over the
past decade on the "Thalictrum" alkaloids. Forty-six new alkaloids
are described from fifteen species of the genus "Thalictrum," as
well as 116 alkaloids of known structure from thirty-six species
and subspecies of the genus. The chapter includes discussions of
isolation and structure elucidation, analysis, biosynthesis, cell
culture, and pharmacology. Also featured are inclusive compilations
of botanical sources, alkaloids by alkaloid types, and calculated
molecular weights of the "Thalictrum" alkaloids.
Chapter 2 by Giovanni Appendino provides a fascinating treatment
of Taxine, a collective name referring to a mixture of diterpenoid
alkaloids from the yew tree (genus: "Taxus"). Taxine is responsible
for the toxic properties of the yew tree that has been documented
in historical and fictional literature, from Julius Caesar to
Shakespeare, and from Agatha Christie to T.S. Eliot. The chapter
treats the history, isolation techniques, structure elucidation,
chemistry, and pharmacology of Taxine.
Chapter 3 by Mary D. Menachery surveys the alkaloids of South
American Menispermaceae (moonseed family). Many different
structural types are included in this family. The alkaloid-bearing
plants are woody-vines, shrubs, or small trees. Several of these
species possess potent curare activity. The chemistry as well as
pharmacology of these alkaloids is summarized.
Chapter 4 by Russell J. Molyneux, Robert J. Nash, and Naoki
Asano treats the chemistry and biological activity of the
calystegines and related "nor"tropane alkaloids. These
polyhydroxylated bicyclic alkaloids represent another class of
compounds that inhibit glycosidases, producing profound effects in
biological systems by disrupting the essential cellular function of
glycoprotein processing.
Chapter 5, a related chapter by Robert J. Nash, Naoki Asano, and
Alison A. Watson, reviews polyhydroxylated alkaloids that inhibit
glycosidases. Topics covered include distribution, ecological
significance and toxicity, isolation, synthesis, and
biosynthesis.
This reference has been written for emergency response personnel,
plant safety specialists, and emergency response coordinators. It
has been prepared at a practical level to assist both in training
safety personnel and to provide technical information that can
assist in responding to a hazard material incident that could lead
to a fire hazard situation. Considerable information and technical
data are given on petroleum-based products since these are among
the most widely consumed products; however, the reader will find
ample information on other chemicals. Fire situations pose one of
the most serious problems in an industrial setting, with the
potential loss of lives and property, as well as damage to the
environment. Proper response by trained personnel, as well as
careful preplanning can minimize the risk and damage caused by
fire.
Since publication of the first edition in 1988 many significant
advances have occurred in IC chips that have driven the hybrid
packaging processes toward even higher densities and greater
performance. The almost exponential increase in density,
complexity, and performance of integrated circuits over the past
ten years (for example, ASIC (Application Specific Integrated
Circuit), VHSIC (Very High Speed IC), VLSIC (Very Large Scale IC),
and ULSIC (Ultra Large Scale IC) have driven developments in the
interconnect substrates culminating in what is now known as
multichip modules (MCM). However, the fundamentals of design,
fabrication, and testing of MCMs are essentially the same as for
hybrid microcircuit. In the authors' opinion MCMs are extensions of
hybrid circuits that can accommodate the new generation of
high-speed high-performance chips.
In this revised edition they have therefore expanded their
treatment of hybrid circuits without finding it necessary to change
the fundamentals. They have included a separate chapter on
multichip modules and throughout the book have included new and
emerging materials and processes that are beginning to be used.
Examples include: metal-matrix composites and aluminum nitride as
substrate materials, plastic encapsulated microcircuits and
chip-on-board as low-cost alternatives to hermetic sealed packages,
atmospheric friendly cleaning solvents and methods, and advanced
high I/O density quad flat packages (QFP) and ball grid array (BGA)
packages. Since the first edition, there have also been tremendous
advances in software programs for thermal and electrical analysis
and these are also treated in this new edition.
The abbreviated Table ofContents below includes the chapter
titles and selected sub-headings.
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