Elsevier now offers a series of derivative works based on the acclaimed "Meyler s Side Effect of Drugs, 15th Edition." These individual volumes are grouped by specialty to benefit the practicing biomedical researcher and/or clinician.
There has been significant progress in the development of targeted therapy drugs that act specifically on certain cancers, and that minimize damage to normal cells. Oncologists and cancer researchers will rely on this volume to determine effective drug treatments.
* The only drug guide that includes clinical case studies and expert analysis
* "UNIQUE " Features not only anticancer drugs, but also all other drugs that act upon related organ systems affected by cancer
* Most complete cross referencing of drug-drug interactions available
* Latest content from the most highly regarded compilation of drug side effects: "Side Effects of Drugs Annual" serial"

The new edition of "Crew Resource Management" continues to focus on CRM in the cockpit, but also emphasizes that the concepts and training applications provide generic guidance and lessons learned for a wide variety of "crews" in the aviation system as well as in the complex and high-risk operations of many non-aviation settings.

Long considered the "bible" in this field, much of the basic style and structure of the previous edition of Crew "Resource Management" is retained in the new edition. Textbooks are often heavily supplemented with or replaced entirely by course packs in advanced courses in the aviation field, as it is essential to provide students with cutting edge information from academic researchers, government agencies (FAA), pilot associations, and technology (Boeing, ALION). This edited textbook offers ideal coverage with first-hand information from each of these perspectives. Case examples, which are particularly important given the dangers inherent in real world aviation scenarios, are liberally supplied. An image collection and test bank make this the only text on the market with ancillary support.

New material includes: international and cultural aspects of CRM; design and implementation of Line-Oriented Flight Training (LOFT); airline applications beyond the cockpit; spaceflight resource management; non-aviation applications; AQP; LOSA; and special issues pertaining to low-cost airline carriers.

The second edition editors offer essential breath of experience in aviation human factors from multiple perspectives (academia, government, and private enterprise) and the contributors have all been chosen as experts in their fields who represent the diversity of the research of activities and organisational experience of CRM.
The only CRM text on the market offering an up-to-date synthesis of primary source materialNew edition thoroughly updated and revised to include major new findings, complete with discussion of the international and cultural aspects of CRM, the design and implementation of LOFTInstructor website with testbank and image collectionLiberal use of case examples

Applied Behavior Analysis is the science of applying experimentally derived principles of behavior to improve socially significant behavior. The research and application of ABA contributes to a wide range of practical areas, including AIDS prevention, education, gerontology, language acquisition and parenting, and ABA-based interventions have gained particular popularity in the last 20 years related to teaching students with autism spectrum disorders. Social Validity, a concept used in such behavioral intervention research, focuses on whether the goals of treatment, the intervention techniques used and the outcomes achieved are acceptable, relevant, and useful to the individual in treatment. Judgments are made (often via clinical trials) about the effects of the intervention based on statistical significance and magnitude of effect. Essentially, social validity alerts us as to whether or not the ABA-based intervention has had a palpable impact and actually helped people in ways that are evident in everyday life.
This clinical research volume offers a detailed evaluation of the extant findings on Social Validity, as well as discussion of newly emerging factors which reemphasize the need for well-developed methods of examining SV. Basic conceptualizations, measurement, research findings, applications, ethics, and future implications are discussed in full, and novel recommendations relating back to clinical treatment are provided. The volume will give readers a firm understanding of the general concept of SV, help them become familiar with the research methods and findings, and teach them how to establish and evaluate the Social Validity of individual interventions and treatment programs.
Consolidates literature broadly distributed across journals and book chapters into single source
Provides discussion of SV in greater depth and breadth than is found in other sources, which generally just focus on general conceptualization and broad research findings
Describes how concept of SV can be influential in numerous areas of clinical practice

Linear Algebra: An Introduction With Mathematica uses a matrix-based presentation and covers the standard topics any mathematician will need to understand linear algebra while using Mathematica. Development of analytical and computational skills is emphasized, and worked examples provide step-by-step methods for solving basic problems using Mathematica. The subject's rich pertinence to problem solving across disciplines is illustrated with applications in engineering, the natural sciences, computer animation, and statistics.

This volume presents articles from the leading experts in the field in nanobiotechnology, providing students and researchers with a comprehensive review of the newly emerging area of neuroscience.

All aspects of nanomaterials induced alteration in brain function are considered. Basic chapters on methods and ways to enhance nano-drug delivery into the brain are presented as well as chapters on functional and structural changes in the CNS, including gene expression and related issues. Particular attention is given to possible therapeutic advancement regarding nano-drug formulation and their role in neuroprotection.

Elsevier now offers a series of derivative works based on the acclaimed "Meyler s Side Effect of Drugs, 15th Edition." These individual volumes are grouped by specialty to benefit the practicing biomedical researcher and/or clinician.
This volume is essential for internal medicine physicians and general practitioners who prescribe antibiotic drugs, like penicillin and tetracycline that cure bacterial infections, and antiviral drugs used to treat patients with HIV and herpes viruses.
* The only drug guide that includes clinical case studies and expert analysis
* "UNIQUE " Features not only antimicrobial drugs, but also all other drugs that act in an anti-microbial manner
* Most complete cross referencing of drug-drug interactions available
* Latest content from the most highly regarded compilation of drug side effects: "Side Effects of Drugs Annual" serial"

This handbook provides a consolidated, comprehensive information resource for engineers working with mission and safety critical systems. Principles, regulations, and processes common to all critical design projects are introduced in the opening chapters. Expert contributors then offer development models, process templates, and documentation guidelines from their own core critical applications fields: medical, aerospace, and military. Readers will gain in-depth knowledge of how to avoid common pitfalls and meet even the strictest certification standards. Particular emphasis is placed on best practices, design tradeoffs, and testing procedures.
*Comprehensive coverage of all key concerns for designers of critical systems including standards compliance, verification and validation, and design tradeoffs
*Real-world case studies contained within these pages provide insight from experience

China s rapid economic expansion raises questions internally and externally about how it will acquire the energy it needs to sustain growth. Currently it is the largest producer and consumer of coal; how much will it continue to rely on its abundant natural resource in the face of increasing environmental concerns? Will it embrace new clean coal technologies developed by others or invest in its own? Currently it imports 50% of the oil it consumes; will it invest in technologies that scrub the ocean floor for petroleum deposits? Will it develop new distribution technologies to bring its natural gas reserves closer to population centers? What role will conservation play? And how will China relate to the rest of the international community as it addresses these critical issues.

Research on Energy Issues In Chinapresents one prominent insider s view of China s key energy issues and his strategy for addressing them. A collection of papers authored by Jiang Zemin, former president of the People s Republic of China, it appears here in English for the first time. Jiang s message is an exhortation to the Chinese to invest in science and technology, and research and development, to ensure the steady supply of energy so crucial for sustaining and driving development. He outlines this energy strategy for China: "we need to steadfastly conserve energy, use it efficiently, diversify development, keep the environment clean, be technology driven and cooperate internationally in order to establish a system of energy production, distribution and consumption that is highly efficient, uses advanced technology, produces few pollutant, has minimal impact on the ecosystem, and provides a steady and secure energy supply."

Within ten to twenty years, China may well be the world s largest energy consumption and supply system. This volume offers policy makers, energy industry analysts, researchers, and investors an inside view of how it plans to get there.
Compares China s current energy situation with the developed world.

Details specific challenges and opportunities in China with respect to coal, oil, nuclear, natural gas, solar, biomass, hydrogen, geothermal, wind, and ocean

Presents an eight point energy development policy

Provides a guide to China s future investment in research and development. "

In the forty-eight years that have gone by since the first volume of Progress in Optics was published, optics has become one of the most dynamic fields of science. The volumes in this series which have appeared up to now contain more than 300 review articles by distinguished research workers, which have become permanent records for many important developments.
- 3D optical microscopy
- Transformation optics and geometry of light
- Photorefractive solitons
- Stimulated scattering effects
- Optical vortices and polarization singularities
- Quantum feedforward control of light

Quantification and modalities have always been topics of great interest for logicians. These two themes emerged from philosophy and
language in ancient times; they were studied by traditional informal
methods until the 20th century. In the last century the tools became
highly mathematical, and both modal logic and quantification found numerous applications in Computer Science. At the same time many other kinds of nonclassical logics were investigated and applied to Computer Science.
Although there exist several good books in propositional modal logics, this book is the first detailed monograph in nonclassical first-order quantification. It includes results obtained during the past thirty years. The field is very large, so we confine ourselves with only two kinds of logics: modal and superintuitionistic. The main emphasis of Volume 1 is model-theoretic, and it concentrates on descriptions of different sound semantics and completeness problem --- even for these seemingly simple questions we have our hands full. The major part of the presented material has never been published before. Some results are very recent, and for other results we either give new proofs or first proofs in full detail.

Handbook of Differential Equations: Evolutionary Equations is the last text of a five-volume reference in mathematics and methodology. This volume follows the format set by the preceding volumes, presenting numerous contributions that reflect the nature of the area of evolutionary partial differential equations. The book is comprised of five chapters that feature the following: A thorough discussion of the shallow-equations theory, which is used as a model for water waves in rivers, lakes and oceans. It covers the issues of modeling, analysis and applications * Evaluation of the singular limits of reaction-diffusion systems, where the reaction is fast compared to the other processes; and applications that range from the theory of the evolution of certain biological processes to the phenomena of Turing and cross-diffusion instability Detailed discussion of numerous problems arising from nonlinear optics, at the high-frequency and high-intensity regime * Geometric and diffractive optics, including wave interactions Presentation of the issues of existence, blow-up and asymptotic stability of solutions, from the equations of solutions to the equations of linear and non-linear thermoelasticity Answers to questions about unique space, such as continuation and backward uniqueness for linear second-order parabolic equations. Research mathematicians, mathematics lecturers and instructors, and academic students will find this book invaluable

Gas phase molecular spectroscopy is a powerful tool for obtaining information on the geometry and internal structure of isolated molecules as well as on the interactions that they undergo. It enables the study of fundamental parameters and processes and is also used for the sounding of gas media through optical techniques. It has been facing always renewed challenges, due to the considerable improvement of experimental techniques and the increasing demand for accuracy and scope of remote sensing applications.
In practice, the radiating molecule is usually not isolated but diluted in a mixture at significant total pressure. The collisions among the molecules composing the gas can have a large influence on the spectral shape, affecting all wavelength regions through various mechanisms. These must be taken into account for the correct analysis and prediction of the resulting spectra.
This book reviews our current experimental and theoretical knowledge and the practical consequences of collisional effects on molecular spectral shapes in neutral gases. General expressions are first given. They are formal of difficult use for practical calculations often but enable discussion of the approximations leading to simplified situations. The first case examined is that of isolated transitions, with the usual pressure broadening and shifting but also refined effects due to speed dependence and collision-induced velocity changes. Collisional line-mixing, which invalidates the notion of isolated transitions and has spectral consequences when lines are closely spaced, is then discussed within the impact approximation. Regions where the contributions of many distant lines overlap, such as troughsbetween transitions and band wings, are considered next. For a description of these far wings the finite duration of collisions and concomitant breakdown of the impact approximation must be taken into account. Finally, for long paths or elevated pressures, the dipole or polarizability induced by intermolecular interactions can make significant contributions. Specific models for the description of these collision induced absorption and light scattering processes are presented.
The above mentioned topics are reviewed and discussed from a threefold point of view: the various models, the available data, and the consequences for applications including heat transfer, remote sensing and optical sounding. The extensive bibliography and discussion of some remaining problems complete the text.
- State of the art on the subject
- A bibliography of nearly 1000 references
- Tools for practical calculations
- Consequences for other scientific fields
- Numerous illustrative examples
- Fulfilling a need since there is no equivalent monograph on the subject

Elsevier now offers a series of derivative works based on the acclaimed Meylers Side Effect of Drugs, 15th Edition. These individual volumes are grouped by specialty to benefit the practicing physician or health care clinician.

Each year, heart disease kills more people than cancer. Patients are treated by a variety of specialists and primary care practitioners, depending on the organ system involved. This volume enables practitioners to assess the adverse effects of the complete range of drugs used in cardiovascular medicine, including antihypertensive drugs, and drugs used in the treatment of heart failure, angina, angina pectoris, and cardiac arrhythmia and enable practitioners to prescribe preventative treatments with medications such as blood pressure reducers, aspirin, and cholesterol-lowering drugs, as well as drugs used for more aggressive therapy.

The material is drawn from the 15th edition of the internationally renowned encyclopedia, Meyler s Side Effects of Drugs, and the latest volumes in the companion series, Side Effects of Drugs Annuals. Drug names have usually been designated by their recommended or proposed International Non-proprietary Names (rINN or pINN); when those are not available, clinical names have been used. In some cases, brand names have been used.

This volume is critical for any health professional involved in the administration of cardiovascular mediations.
Surpasses the Physician s Desk Reference (c) by including clinical case studies and independent expert analysisComplete index of drug namesMost complete cross referencing of drug-drug interactions availableExtensive references to primary and secondary literatureAlso includes information on adverse effects in pregnancy

The book is divided into six sections:

Drugs used to treat hypertension, heart failure and angina pectorisDiuretics - a general introduction to their adverse effects, followed by monographs on individual drugsAntidysrhythmic drugs - a general introduction to their adverse effects, followed by monographs on individual drugsDrugs that act on the cerebral and peripheral circulationsAnticoagulants, thrombolytic agents, and anti-platelet drugsCardiovascular adverse effects of non-cardiovascular drugs "

The book documents and explains, in three parts, geochemical anomaly and mineral prospectivity mapping by using a geographic information system (GIS). Part I reviews and couples the concepts of (a) mapping geochemical anomalies and mineral prospectivity and (b) spatial data models, management and operations in a GIS. Part II demonstrates GIS-aided and GIS-based techniques for analysis of robust thresholds in mapping of geochemical anomalies. Part III explains GIS-aided and GIS-based techniques for spatial data analysis and geo-information sybthesis for conceptual and predictive modeling of mineral prospectivity. Because methods of geochemical anomaly mapping and mineral potential mapping are highly specialized yet diverse, the book explains only methods in which GIS plays an important role. The book avoids using language and functional organization of particular commercial GIS software, but explains, where necessary, GIS functionality and spatial data structures appropriate to problems in geochemical anomaly mapping and mineral potential mapping. Because GIS-based methods of spatial data analysis and spatial data integration are quantitative, which can be complicated to non-numerate readers, the book simplifies explanations of mathematical concepts and their applications so that the methods demonstrated would be useful to professional geoscientists, to mineral explorationists and to research students in fields that involve analysis and integration of maps or spatial datasets. The book provides adequate illustrations for more thorough explanation of the various concepts.
*Explains GIS functionality and spatial data structures appropriate regardless of the particular GIS software in use
*Simplifies explanation of mathematical concepts and application
*Illustrated for more thorough explanation of concepts

The Newnes Know It All Series takes the best of what our authors have written to create hard-working desk references that will be an engineer's first port of call for key information, design techniques and rules of thumb. Guaranteed not to gather dust on a shelf
Field Application engineers need to master a wide area of topics to excel. The "Test and Measurement Know It All" covers every angle including Machine Vision and Inspection, Communications Testing, Compliance Testing, along with Automotive, Aerospace, and Defense testing.
A 360-degree view from our best-selling authors
Topics include the Technology of Test and Measurement, Measurement System Types, and Instrumentation for Test and Measurement.
The ultimate hard-working desk reference; all the essential information, techniques and tricks of the trade in one volume"

This second volume of a two-part series examines three major topics. First, it devotes five chapters to the classical issue of capital structure choice. Second, it focuses on the value-implications of major corporate investment and restructuring decisions, and then concludes by surveying the role of pay-for-performance type executive compensation contracts on managerial incentives and risk-taking behavior.
In collaboration with the first volume, this handbook takes stock of the main empirical findings to date across an unprecedented spectrum of corporate finance issues. The surveys are written by leading empirical researchers that remain active in their respective areas of interest. With few exceptions, the writing style makes the chapters accessible to industry practitioners. For doctoral students and seasoned academics, the surveys offer dense roadmaps into the empirical research landscape and provide suggestions for future work.
* Nine original chapters summarize research advances and future topics in the classical issues of capital structure choice, corporate investment behavior, and firm value.
* Multinational comparisons underline the volume's empirical perspectives
* Complements the presentation of econometric issues, banking, and capital acquisition research covered by Volume 1

Written from the practitioner's perspective, this book is designed as a companion for engineers who are working in the field and faced with various problems related to pressure vessels and stacks, such as: modification, retrofitting existing pressure vessels or stacks to either enhance process capability, lift, move or replace damaged equipment. This makes the book a valuable guide for new engineers who need to develop a feel for these types of operations or more experienced engineers who wish to acquire more useful tips, this handy manual provides the readers with rules of thumbs and tips to mitigate or remediate problems which can occur on a daily bases.
Because of their size, complexity, or hazardous contents, pressure vessels and stacks require the highest level of expertise in determining their fitness for service after these operations. Care must be taken in installation / removal of the vessel to avoid damage to the shell. Damage to the shell can result in catastrophic failure and possible injury to personnel. The book will cover topics such as: lifting and tailing devices; an overview of rigging equipment; safety consideration; inspection and repair tips; methods to avoid dynamic resonance in pressure vessels and stacks; wind loads and how to apply them for various applications and assessment guidelines for column internals, tables and pressure vessel calculations, and code formulas.
The examples in the book are actual field applications based on 40+ years of experience from various parts of the world and are written from a view to enhance field operations. In many parts of the world, often in remote locations, these methods were applied to repair pressure vessels and stacks. These problems will still continue to happen, so there is a need to know how to address them. This book is to present assessments and techniques and methods for the repair of pressure vessels and stacks for field applications. Also the book is to be a repair manual for easy use for mechanical engineers, civil-structural engineers, plant operators, maintenance engineers, plant engineers and inspectors, materials specialists, consultants, and academicians.

Lifting and tailing devices
An overview of rigging equipment
Inspection and repair tips
Guidelines for column internals
Tables and pressure vessel calculations, and code formulas.

The growth of financial intermediation research has yielded a host of questions that have pushed "design" issues to the fore even as the boundary between financial intermediation and corporate finance has blurred. This volume presents review articles on six major topics that are connected by information-theoretic tools and characterized by valuable perspectives and important questions for future research. Touching upon a wide range of issues pertaining to the designs of securities, institutions, trading mechanisms and markets, industry structure, and regulation, this volume will encourage bold new efforts to shape financial intermediaries in the future.
* Original review articles offer valuable perspectives on research issues appearing in top journals
* Twenty articles are grouped by six major topics, together defining the leading research edge of financial intermediation
* Corporate finance researchers will find affinities in the tools, methods, and conclusions featured in these articles

The sixteen papers collected in this volume are expanded and revised versions of talks delivered at the Second International Conference on the Ontology of Spacetime, organized by the International Society for the Advanced Study of Spacetime (John Earman, President) at Concordia University (Montreal) from 9 to 11 June 2006.
Most chapters are devoted to subjects directly relating to the ontology of spacetime.
The book starts with four papers that discuss the ontological status of spacetime and the processes occurring in it from a point of view that is first of all conceptual and philosophical. The focus then slightly shifts in the five papers that follow, to considerations more directly involving technical considerations from relativity theory. After this, Time, Becoming and Change take centre stage in the next five papers. The book ends with two excursions into relatively uncharted territory: a consideration of the status of Kaluza-Klein theory, and an investigation of possible relations between the nature of spacetime and condensed matter physics, respectively.
- Space and time in present-day physics and philosophy
- Relatively low level of technicality, easily accessible
- Introduction from scratch of the debates surrounding time
- Broad spectrum of approaches, coherently represented

This handbook is the fourth volume in a series of volumes devoted to self-contained and up-to-date surveys in the theory of ordinary differential equations, with an additional effort to achieve readability for mathematicians and scientists from other related fields so that the chapters have been made accessible to a wider audience.
* Covers a variety of problems in ordinary differential equations
* Pure mathematical and real-world applications
* Written for mathematicians and scientists of many related fields

This handbook is the sixth and last volume in the series devoted to stationary partial differential equations. The topics covered by this volume include in particular domain perturbations for boundary value problems, singular solutions of semilinear elliptic problems, positive solutions to elliptic equations on unbounded domains, symmetry of solutions, stationary compressible Navier-Stokes equation, Lotka-Volterra systems with cross-diffusion, and fixed point theory for elliptic boundary value problems.
* Collection of self-contained, state-of-the-art surveys
* Written by well-known experts in the field
* Informs and updates on all the latest developments

Hiring highly qualified people is crucial to every company, and Background Screening and Investigations is an essential guide to succeeding in a turbulent business environment. A crucial part of any hiring process should be employment background screening, pre- and post-hire, which gives hiring personnel a glimpse into a person's past behavior patterns, propensities, and likely future behavior.
Background Screening and Investigations describes all aspects of the employment background screening processes - its history and evolution, the imperative for implementing a screening process, and the creation of a comprehensive policy. Nixon and Kerr show how security and human resources professionals can work together to negotiate legal hurdles and make their background screening process successful.
* Where do HR and security perspectives differ on hot topics like hiring convicted felons, data protection, and sexual predators?
* What does state law allow when screening job candidates?
* How should companies deal with emerging issues like international background investigations and continuous (Infinity) screening of current employees?

This book begins with an overview of current thinking on bioavailability, its definition, cutting edge research in speciation and advancement in tools for assessing chemical bioavailability in the terrestrial environment. The second section of the book focuses on the role of chemical speciation in bioavailability. Section three addresses bioavailability and ecotoxicity of contaminants and leads into the next section on bioavailability of nutrients and agrichemicals. Subsequent sections provide an overview of tools currently being used and new cutting edge techniques to assess contaminant bioavailability. The last section of the book builds on previous sections in relating bioavailability to risk assessment and how this could be used for managing risks associated with contaminated land.
* Provides the latest information on developing concepts and definitions of bioavailability
* Includes a discussion of bioavailability and ecotoxicity of contaminants and bioavailability of nutrients and agrichemicals for applications in agriculture
* Analysizes tools for assessing bioavailability and the role of bioavailability in risk assessment and remediation

A collection of self contained state-of-the art surveys. The authors have made an effort to achieve readability for mathematicians and scientists from other fields, for this series of handbooks to be a new reference for research, learning and teaching.
* Written by well-known experts in the field
* Self contained volume in series covering one of the most rapid developing topics in mathematics
* Informed and thoroughly updated for students, academics and researchers

Newnes has worked with Marty Brown, a leader in the field of power design to select the very best design-specific material from the Newnes portfolio. Marty selected material for its timelessness, its relevance to current power supply design needs, and its real-world approach to design issues. Special attention is given to switching power supplies and their design issues, including component selection, minimization of EMI, toroid selection, and breadboarding of designs. Emphasis is also placed on design strategies for power supplies, including case histories and design examples. This is a book that belongs on the workbench of every power supply designer!
*Marty Brown, author and power supply design consultant, has personally selected all content for its relevance and usefulness
*Covers best design practices for switching power supplies and power converters
*Emphasis is on pragmatic solutions to commonly encountered design problems and tasks