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Books > Academic & Education > Professional & Technical
Stress is a universal phenomenon that impacts adversely on most
people. This volume provides a readily accessible compendium that
focuses on the physical and psychological consequences of stress
for individuals and society. Clinical attention focuses on
disorders of the stress control system (e.g. Cushing s Syndrome:
Addison s Disease) and the adverse impact of stress on human
physical and mental health. Detailed reviews address disorders such
as PTSD, anxiety, major depression, psychoses and related disorders
such as combat fatigue and burnout. The work covers interactions
between stress and neurodegenerative disorders, such as Alzheimer s
disease and Parkinson s disease, as well as
stress-immune-inflammatory interactions in relation to cancer and
autoimmune and viral diseases. Emphasis is also placed on the role
of stress in obesity, hypertension, diabetes type II and other
features of the metabolic syndrome which has now reached epidemic
proportions in the USA and other countries.
Intercellular communication is part of a complex system of
communication that governs basic cellular activities and
coordinates cell actions. The ability of cells to perceive and
correctly respond to their environment is the basis of growth and
development, tissue repair, and immunity as well as normal tissue
homeostasis. Errors in cellular information processing are
responsible for diseases such as cancer, autoimmunity, diabetes,
and neurological and psychiatric disorders. There is substantial
drug development concentrating on this and intercellular
communication is the basis of much of neuropharmacology. By
understanding cell signaling, diseases may be treated effectively
and, theoretically, artificial tissues may be yielded.
Neurotransmitters/receptors, synaptic structure and organization,
gap junctions, neurotrophic factors and neuropeptides are all
explored in this volume, as are the ways in which signaling
controls neuroendocrinology, neuroimmunology and neuropharmacology.
"Intercellular Communication in the Nervous System"provides a
valuable desk reference for all scientists who consider
signaling. * Chapters offer impressive scope with topics addressing neurotransmitters/receptors, synaptic structure and organization, neuropeptides, gap junctions, neuropharmacology and more * Richly illustrated in full color with over 200 figures * Contributors represent the most outstanding scholarship in the field, with each chapter providing fully vetted and reliable expert knowledge"
By their very nature, construction projects can create seemingly
endless opportunities for conflict. Written by a best selling
author with over 40 years of experiences in the construction and
general contracting business, Construction Process Planning and
Management provides you with the necessary tools to save time and
money on your construction project. In this book, Sid Levy provides
valuable advice for avoiding or working through the common problems
that are a result of the long-term nature of construction projects,
failure to select a ?project delivery system? appropriate to the
project, incomplete drawing and specifications, unrealistic
scheduling, poor communication and coordination among participants,
and inadequate contract administration. From project genesis,
through design development to contractor and contract selection, on
to construction oversight, punch list and successful project
close-out, this book will point out those pitfalls to avoid and
offer practical advice at every step along the way.
Materials Science for Engineering Students offers students of
introductory materials science and engineering, and their
instructors, a fresh perspective on the rapidly evolving world of
advanced engineering materials. This new, concise text takes a more
contemporary approach to materials science than the more
traditional books in this subject, with a special emphasis on using
an inductive method to first introduce materials and their
particular properties and then to explain the underlying physical
and chemical phenomena responsible for those properties. The text
pays particular attention to the newer classes of materials, such
as ceramics, polymers and composites, and treats them as part of
two essential classes, structural materials and functional
materials, rather than the traditional method of emphasizing
structural materials alone.
The Bayesian network is one of the most important architectures for representing and reasoning with multivariate probability distributions. When used in conjunction with specialized informatics, possibilities of real-world applications are achieved. Probabilistic Methods for BioInformatics explains the application of probability and statistics, in particular Bayesian networks, to genetics. This book provides background material on probability, statistics, and genetics, and then moves on to discuss Bayesian networks and applications to bioinformatics. Rather than getting bogged down in proofs and algorithms,
probabilistic methods used for biological information and Bayesian
networks are explained in an accessible way using applications and
case studies. The many useful applications of Bayesian networks
that have been developed in the past 10 years are discussed.
Forming a review of all the significant work in the field that will
arguably become the most prevalent method in biological data
analysis.
Industrialists developing new food and pharmaceutical products face
the challenge of innovation in an increasingly competitive market
that must consider incredient cost, product added-value,
expectations of a healthy life-style, improved sensory impact,
controlled delivery of active compounds and last, but not lease,
product stability. While much work has been done to explore,
understand, and address these issues, a gap has emerged between
recent advances in fundamental knowledge and its direct application
to product situations with a growing need for scientific input.
This volume provides a broad overview of important new advances in
the field of Neuropharmacology. In 20 chapters, a selection of
international contributors discuss topics including endocannabinoid
function, pain, stress, astrocytes etc, and new possibilities for
treatments of neurological diseases with neuropharmacological
approaches.
Multi-scale analysis and simulation of chemical processing and reactions have received unprecedented attention in recent years; however, measurement technology focused on multi-scale structures, particularly on meso-scale phenomena, has not been sufficiently addressed. This volume of "Advances in Chemical Engineering" focuses on the ""Characterization of Flow, Particles and Interfaces" "to alert the chemical engineering community to this challenging issue presenting six meso-scale measurement technologies.
The Eclipse environment solves the problem of having to maintain
your own Integrated Development Environment (IDE), which is time
consuming and costly. Embedded tools can also be easily integrated
into Eclipse. The C/C++CDT is ideal for the embedded community with
more than 70% of embedded developers using this language to write
embedded code. Eclipse simplifies embedded system development and
then eases its integration into larger platforms and frameworks.
The importance of chloride ions in cell physiology has not been
fully recognized until recently, in spite of the fact that chloride
(Cl-), together with bicarbonate, is the most abundant free anion
in animal cells, and performs or determines fundamental biological
functions in all tissues. For many years it was thought that Cl-
was distributed in thermodynamic equilibrium across the plasma
membrane of most cells. Research carried out during the last couple
of decades has led to a dramatic change in this simplistic view. We
now know that most animal cells, neurons included, exhibit a
non-equilibrium distribution of Cl- across their plasma membranes.
Over the last 10 to 15 years, with the growth of molecular biology
and the advent of new optical methods, an enormous amount of
exciting new information has become available on the molecular
structure and function of Cl- channels and carriers. In nerve
cells, Cl- channels and carriers play key functional roles in GABA-
and glycine-mediated synaptic inhibition, neuronal growth and
development, extracellular potassium scavenging,
sensory-transduction, neurotransmitter uptake and cell volume
control. Disruption of Cl- homeostasis in neurons underlies
pathological conditions such as epilepsy, deafness, imbalance,
brain edema and ischemia, pain and neurogenic inflammation. This
book is about how chloride ions are regulated and how they cross
the plasma membrane of neurons. It spans from molecular structure
and function of carriers and channels involved in Cl- transport to
their role in various diseases.
This well-established international series examines major areas of basic and clinical research within neuroscience, as well as emerging and promising subfields. This volume explores interdisciplinary research on Attention and interaction of Attention with other cognitive processes including perception, learning, and memory. The papers cover major research on attention in Cognitive Neuroscience and Cognitive Psychology. The volume presents recent advances on attention including binding, dynamics of attention, attention and perceptual organization, attention and consciousness, emotion and attention, development of attention, crossmodal attention, computational modeling of attention, control of actions, attention and memory, and meditation.
Mobile communications users are demanding increased reliability,
functionality, and accessibility; they want "always on" access to
voice, e-mail, text, and multimedia services as they roam from home
to auto to office to outdoor/indoor locations. In addition, there
is an increasing deamnd to replace separate landline/mobile
telephones with a single handset that can be used wherever its
owner might be. Answering those customer needs, fixed/mobile
convergence (FMC) marries the mobility provided by cellular
networks with the extended connectivity provided by 802.11-based
WiFi services and integrates them with landline networks using a
single handset. This book provides the theoretical and practical
background necessary to successfully plan, develop, and deploy
effective FMC networks.
"Neurological Disorders" is written for researchers in both academia and the pharmaceutical industry who use animal models in research and development of drugs for neurological disorders such as neurofibromatosis, Alzheimer s disease, Parkinson s disease, Huntington disease, ALS, and the epilepsies. "Neurological Disorders "has introductory chapters expressing the view of the role and relevance of animal models for drug discovery and development for the treatment of psychiatric disorders from the perspective of (a) academic basic neuroscientific research, (b) applied pharmaceutical drug discovery and development, and (c) issues of clinical trial design and regulatory agencies limitations. Each volume examines the rationale, use, robustness and limitations of animal models in each therapeutic area covered and discuss the use of animal models for target identification and validation. The clinical relevance of animal models is discussed in terms of major limitations in cross-species comparisons, clinical trial design of drug candidates, and how clinical trial endpoints could be improved. The aim of this series of volumes on "Animal and Translational Models for CNS Drug Discovery" is to identify and provide common endpoints between species that can serve to inform both the clinic and the bench with the information needed to accelerate clinically-effective CNS drug discovery. This is the second volume in the three volume-set, "Animal and
Translational Models for CNS Drug Discovery" 978-0-12-373861-5,
which is also available for purchase individually.
"Psychiatric Disorders" is written for researchers in both academia and the pharmaceutical industry who use animal models in research and development of drugs for psychiatric disorders such as anxiety, obsessive-compulsive disorder, depression, schizophrenia, bipolar disorder, ADHD, and autistic spectrum disorder. "Psychiatric Disorders "has introductory chapters expressing the view of the role and relevance of animal models for drug discovery and development for the treatment of psychiatric disorders from the perspective of (a) academic basic neuroscientific research, (b) applied pharmaceutical drug discovery and development, and (c) issues of clinical trial design and regulatory agencies limitations. Each volume examines the rationale, use, robustness and limitations of animal models in each therapeutic area covered and discuss the use of animal models for target identification and validation. The clinical relevance of animal models is discussed in terms of major limitations in cross-species comparisons, clinical trial design of drug candidates, and how clinical trial endpoints could be improved. The aim of this series of volumes on "Animal and Translational Models for CNS Drug Discovery" is to identify and provide common endpoints between species that can serve to inform both the clinic and the bench with the information needed to accelerate clinically-effective CNS drug discovery. This is the first volume in the three volume-set, "Animal and
Translational Models for CNS Drug Discovery" 978-0-12-373861-5,
andis also available for purchase individually.
"Advances in Imaging and Electron Physics" merges two long-running
serials--"Advances in Electronics and Electron Physics" and
"Advances in Optical and Electron Microscopy." This series features
extended articles on the physics of electron devices (especially
semiconductor devices), particle optics at high and low energies,
microlithography, image science and digital image processing,
electromagnetic wave propagation, electron microscopy, and the
computing methods used in all these domains.
Advances in Imaging and Electron Physics merges two long-running serials--Advances in Electronics and Electron Physics and Advances in Optical and Electron Microscopy. This series features extended articles on the physics of electron devices (especially semiconductor devices), particle optics at high and low energies, microlithography, image science and digital image processing, electromagnetic wave propagation, electron microscopy, and the computing methods used in all these domains. Updated with contributions from leading international scholars
and industry experts
This volume investigates the implications of how our brain directs
our movements on decision making. An extensive body of knowledge in
chapters from international experts is presented as well as
integrative group reports discussing new directions for future
research.
This volume reviews the techniques Forster Resonance Energy Transfer (FRET) and Fluorescence Lifetime Imaging Microscopy (FLIM) providing researchers with step by step protocols and handy hints and tips. Both have become staple techniques in many biological and biophysical fields.
This book addresses a fundamental question about the nature of
behavior: how does the brain process reward and makes decisions
when facing multiple options? The book presents the most recent and
compelling lesion, neuroimaging, electrophysiological and
computational studies, in combination with hormonal and genetic
studies, which have led to a clearer understanding of neural
mechanisms behind reward and decision making. The neural bases of
reward and decision making processes are of great interest to
scientists because of the fundamental role of reward in a number of
behavioral processes (such as motivation, learning and cognition)
and because of their theoretical and clinical implications for
understanding dysfunctions of the dopaminergic system in several
neurological and psychiatric disorders (schizophrenia, Parkinson's
disease, drug addiction, pathological gambling, ...). * Comprehensive coverage of approaches to studying reward and decision making, including primate neurophysiology and brain imaging studies in healthy humans and in various disorders, genetic and hormonal influences on the reward system and computational models. * Covers clinical implications of process dysfunction (e.g., schizophrenia, Parkinson's disease, eating disorders, drug addiction, pathological gambling) * Uses multiple levels of analysis, from molecular mechanisms to neural systems dynamics and computational models. " "This is a very interesting and authoritative handbook by some of the most outstanding investigators in the field of reward and decision making "," Professor Edmund T. Rolls, Oxford Center for Computational Neuroscience, UK
A single volume of 41 articles, Hormone/Behavior Relations of
Clinical Importance is an authoritative selection of relevant
chapters from the Hormones Brain and Behavior 2e MRW, the most
comprehensive source of neuroendocrinological information assembled
to date (AP July 2009).
Modern embedded systems require high performance, low cost and low power consumption. Such systems typically consist of a heterogeneous collection of processors, specialized memory subsystems, and partially programmable or fixed-function components. This heterogeneity, coupled with issues such as hardware/software partitioning, mapping, scheduling, etc., leads to a large number of design possibilities, making performance debugging and validation of such systems a difficult problem. Embedded systems are used to control safety critical
applications such as flight control, automotive electronics and
healthcare monitoring. Clearly, developing reliable
software/systems for such applications is of utmost importance.
This book describes a host of debugging and verification methods
which can help to achieve this goal.
This book sets out to explain the development of modern electronic
systems and devices from the viewpoint of the semiconductor
materials (germanium, silicon, gallium arsenide and many others)
which made them possible. It covers the scientific understanding of
these materials and its intimate relationship with their technology
and many applications. It began with Michael Faraday, took off in a
big way with the invention of the transistor at Bell Labs in 1947
and is still burgeoning today. It is a story to match any artistic
or engineering achievement of man and this is the first time it has
been presented in a style suited to the non-specialist. It is
written in a lively, non-mathematical style which brings out the
excitement of discovery and the fascinating interplay between the
demands of system pull and technological push. It also looks at the
nature of some of the personal interactions which helped to shape
the modern technological world.
ZigBee is a standard based on the IEEE 802.15.4 standard for
wireless personal networks. This standard allows for the creation
of very lost cost and low power networks - these applications run
for years rather than months. These networks are created from
sensors and actuators and can wireless control many electrical
products such as remote controls, medical, industrial, and security
sensors.
This is the first book dedicated to the developing knowledge on how
the world's largest ice sheet formed and changed over its 34
million years history. In explaining the story of Antartica,
information on terrestrial and marine geology, sedimentology,
glacier geophysics (including airborne reconnaissance), shipborne
geophysics, and numerical ice sheet and climate modelling, will be
interwoven within eleven chapters, each deling with an important
historical theme. The approach will be to first 'set the scene',
involving chapters dedicated to how ice sheets and their glacial
history can be measured. This opening section will provide
information necessary to comprehend the latter section of the book,
in which five chapters will related the glacial and climate
evolution of Antartica during the most important time-frames in
which changes have occurred.
The Textbook of Nephro-Endocrinology is the definitive
translational reference in the field of nephro-endocrinology,
investigating both the endocrine functions of the kidneys and how
the kidney acts as a target for hormones from other organ systems.
It offers both researchers and clinicians expert, gold-standard
analysis of nephro-endocrine research and translation into the
treatment of diseases such as anemia, chronic kidney disease (CKD),
rickets, osteoprosis, and, hypoparathyroidism. |
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