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Books > Academic & Education > Professional & Technical

Stress Consequences - Mental, Neuropsychological and Socioeconomic (Hardcover, New): George Fink Stress Consequences - Mental, Neuropsychological and Socioeconomic (Hardcover, New)
George Fink
R2,832 Discovery Miles 28 320 Ships in 10 - 15 working days

Stress is a universal phenomenon that impacts adversely on most people. This volume provides a readily accessible compendium that focuses on the physical and psychological consequences of stress for individuals and society. Clinical attention focuses on disorders of the stress control system (e.g. Cushing s Syndrome: Addison s Disease) and the adverse impact of stress on human physical and mental health. Detailed reviews address disorders such as PTSD, anxiety, major depression, psychoses and related disorders such as combat fatigue and burnout. The work covers interactions between stress and neurodegenerative disorders, such as Alzheimer s disease and Parkinson s disease, as well as stress-immune-inflammatory interactions in relation to cancer and autoimmune and viral diseases. Emphasis is also placed on the role of stress in obesity, hypertension, diabetes type II and other features of the metabolic syndrome which has now reached epidemic proportions in the USA and other countries.
Chapters offer impressive scope with topics addressing animal studies, disaster, diurnal rhythms, drug effects and treatments, cognition and emotion, physical illness, psychopathology, immunology and inflammation, lab studies and tests, and psychological / biochemical / genetic aspects Richly illustrated in full color with over 200 figures Articles carefully selected by one of the world s most preeminent stress researchers and contributors represent the most outstanding scholarship in the field, with each chapter providing fully vetted and reliable expert knowledge"

Intercellular Communication in the Nervous System (Hardcover): Robert Malenka Intercellular Communication in the Nervous System (Hardcover)
Robert Malenka
R3,241 Discovery Miles 32 410 Ships in 10 - 15 working days

Intercellular communication is part of a complex system of communication that governs basic cellular activities and coordinates cell actions. The ability of cells to perceive and correctly respond to their environment is the basis of growth and development, tissue repair, and immunity as well as normal tissue homeostasis. Errors in cellular information processing are responsible for diseases such as cancer, autoimmunity, diabetes, and neurological and psychiatric disorders. There is substantial drug development concentrating on this and intercellular communication is the basis of much of neuropharmacology. By understanding cell signaling, diseases may be treated effectively and, theoretically, artificial tissues may be yielded. Neurotransmitters/receptors, synaptic structure and organization, gap junctions, neurotrophic factors and neuropeptides are all explored in this volume, as are the ways in which signaling controls neuroendocrinology, neuroimmunology and neuropharmacology. "Intercellular Communication in the Nervous System"provides a valuable desk reference for all scientists who consider signaling.

* Chapters offer impressive scope with topics addressing neurotransmitters/receptors, synaptic structure and organization, neuropeptides, gap junctions, neuropharmacology and more * Richly illustrated in full color with over 200 figures * Contributors represent the most outstanding scholarship in the field, with each chapter providing fully vetted and reliable expert knowledge"

Construction Process Planning and Management - An Owner's Guide to Successful Projects (Hardcover): Sidney M. Levy Construction Process Planning and Management - An Owner's Guide to Successful Projects (Hardcover)
Sidney M. Levy
R1,921 Discovery Miles 19 210 Ships in 10 - 15 working days

By their very nature, construction projects can create seemingly endless opportunities for conflict. Written by a best selling author with over 40 years of experiences in the construction and general contracting business, Construction Process Planning and Management provides you with the necessary tools to save time and money on your construction project. In this book, Sid Levy provides valuable advice for avoiding or working through the common problems that are a result of the long-term nature of construction projects, failure to select a ?project delivery system? appropriate to the project, incomplete drawing and specifications, unrealistic scheduling, poor communication and coordination among participants, and inadequate contract administration. From project genesis, through design development to contractor and contract selection, on to construction oversight, punch list and successful project close-out, this book will point out those pitfalls to avoid and offer practical advice at every step along the way.
Administer the general construction process including solicitation of contractor's qualifications (pre-qualify bidders), comparative analysis of bid packages, recommendation for contract award, contract document negotiation and documentation of job change orders.
Provide Project Planning and on-site management and coordination of all construction projects.
Ensure compliance of building construction rules and regulations and collaborate with chief engineers to monitor quality of construction.
Conduct technical/plan review of construction documents and submit written responses identifying required corrections or changes.
Design, implement and oversee Company standards for construction policies, practices and processes.

Materials Science for Engineering Students (Hardcover): Traugott Fischer Materials Science for Engineering Students (Hardcover)
Traugott Fischer
R2,069 Discovery Miles 20 690 Ships in 10 - 15 working days

Materials Science for Engineering Students offers students of introductory materials science and engineering, and their instructors, a fresh perspective on the rapidly evolving world of advanced engineering materials. This new, concise text takes a more contemporary approach to materials science than the more traditional books in this subject, with a special emphasis on using an inductive method to first introduce materials and their particular properties and then to explain the underlying physical and chemical phenomena responsible for those properties. The text pays particular attention to the newer classes of materials, such as ceramics, polymers and composites, and treats them as part of two essential classes, structural materials and functional materials, rather than the traditional method of emphasizing structural materials alone.
*Presents balanced coverage of both "structural" and "functional" materials.
*Types of materials are introduced first, followed by explanation of physical and chemical phenomena that drive their specific properties.
*Strong focus on engineering applications of materials
*The first materials science text to include a whole chapter devoted to batteries.
*Provides clear, mathematically simple explanations of basic chemistry and physics underlying materials properties.

Probabilistic Methods for Bioinformatics - with an Introduction to Bayesian Networks (Hardcover): Richard E. Neapolitan Probabilistic Methods for Bioinformatics - with an Introduction to Bayesian Networks (Hardcover)
Richard E. Neapolitan
R1,450 Discovery Miles 14 500 Ships in 10 - 15 working days

The Bayesian network is one of the most important architectures for representing and reasoning with multivariate probability distributions. When used in conjunction with specialized informatics, possibilities of real-world applications are achieved. Probabilistic Methods for BioInformatics explains the application of probability and statistics, in particular Bayesian networks, to genetics. This book provides background material on probability, statistics, and genetics, and then moves on to discuss Bayesian networks and applications to bioinformatics.

Rather than getting bogged down in proofs and algorithms, probabilistic methods used for biological information and Bayesian networks are explained in an accessible way using applications and case studies. The many useful applications of Bayesian networks that have been developed in the past 10 years are discussed. Forming a review of all the significant work in the field that will arguably become the most prevalent method in biological data analysis.
Unique coverage of probabilistic reasoning methods applied to bioinformatics data--those methods that are likely to become the standard analysis tools for bioinformatics.Shares insights about when and why probabilistic methods can and cannot be used effectively; Complete review of Bayesian networks and probabilistic methods with a practical approach.

Modern Biopolymer Science - Bridging the Divide between Fundamental Treatise and Industrial Application (Hardcover, New):... Modern Biopolymer Science - Bridging the Divide between Fundamental Treatise and Industrial Application (Hardcover, New)
Stefan Kasapis, Ian T. Norton, Johan B. Ubbink
R3,680 R3,334 Discovery Miles 33 340 Save R346 (9%) Ships in 10 - 15 working days

Industrialists developing new food and pharmaceutical products face the challenge of innovation in an increasingly competitive market that must consider incredient cost, product added-value, expectations of a healthy life-style, improved sensory impact, controlled delivery of active compounds and last, but not lease, product stability. While much work has been done to explore, understand, and address these issues, a gap has emerged between recent advances in fundamental knowledge and its direct application to product situations with a growing need for scientific input.
Modern Biopolymer Science matches science to application by first acknowledging the differing viewpoints between those working with low-solids and those working with high-solids, and then sharing the expertise of those two camps under a unified framework of materials science.

* Real-world utilisation of fundamental science to achieve breakthroughs in product development
* Includes a wide range of related aspects of low and high-solids systems for foods and pharmaceuticals
* Covers more than bio-olymer science in foods by including biopolymer interactions with bioactive compounds, issues of importance in drug delivery and medicinal chemistry

Advances in Neuropharmacology, Volume 85 (Hardcover): Giacinto Bagetta, M. Tiziana Corasaniti, T. Sakurada, S. Sakurada Advances in Neuropharmacology, Volume 85 (Hardcover)
Giacinto Bagetta, M. Tiziana Corasaniti, T. Sakurada, S. Sakurada
R4,866 Discovery Miles 48 660 Ships in 10 - 15 working days

This volume provides a broad overview of important new advances in the field of Neuropharmacology. In 20 chapters, a selection of international contributors discuss topics including endocannabinoid function, pain, stress, astrocytes etc, and new possibilities for treatments of neurological diseases with neuropharmacological approaches.
- Cutting-edge articles in neuropharmacology
- Discusses new possibilities for treatments of neurological disorders
- Very international authorship providing a global view of the state of research

Advances in Chemical Engineering, Volume 37 - Characterization of Flow, Particles and Interfaces (Hardcover, 37th edition):... Advances in Chemical Engineering, Volume 37 - Characterization of Flow, Particles and Interfaces (Hardcover, 37th edition)
Jinghai Li
R5,570 Discovery Miles 55 700 Ships in 10 - 15 working days

Multi-scale analysis and simulation of chemical processing and reactions have received unprecedented attention in recent years; however, measurement technology focused on multi-scale structures, particularly on meso-scale phenomena, has not been sufficiently addressed. This volume of "Advances in Chemical Engineering" focuses on the ""Characterization of Flow, Particles and Interfaces" "to alert the chemical engineering community to this challenging issue presenting six meso-scale measurement technologies.

Embedded Linux Development Using Eclipse (Paperback): Doug Abbott Embedded Linux Development Using Eclipse (Paperback)
Doug Abbott
R1,135 Discovery Miles 11 350 Ships in 10 - 15 working days

The Eclipse environment solves the problem of having to maintain your own Integrated Development Environment (IDE), which is time consuming and costly. Embedded tools can also be easily integrated into Eclipse. The C/C++CDT is ideal for the embedded community with more than 70% of embedded developers using this language to write embedded code. Eclipse simplifies embedded system development and then eases its integration into larger platforms and frameworks.
In this book, Doug Abbott examines Eclipse, an IDE, which can be vital in saving money and time in the design and development of an embedded system. Eclipse was created by IBM in 2001 and then became an open-source project in 2004. Since then it has become the de-facto IDE for embedded developers. Virtually all of the major Linux vendors have adopted this platform, including MontVista, LynuxWorks, and Wind River.
*Details the Eclipse Integrated Development Environment (IDE) essential to streamlining your embedded development process
*Overview of the latest C/C++ Developer's Toolkit (CDT)
*Includes case studies of Eclipse use including Monta Vista, LynuxWorks, and Wind River

Physiology and Pathology of Chloride Transporters and Channels in the Nervous System - From Molecules to Diseases (Hardcover):... Physiology and Pathology of Chloride Transporters and Channels in the Nervous System - From Molecules to Diseases (Hardcover)
F.Javier Alvarez-Leefmans, Eric Delpire
R3,224 Discovery Miles 32 240 Ships in 10 - 15 working days

The importance of chloride ions in cell physiology has not been fully recognized until recently, in spite of the fact that chloride (Cl-), together with bicarbonate, is the most abundant free anion in animal cells, and performs or determines fundamental biological functions in all tissues. For many years it was thought that Cl- was distributed in thermodynamic equilibrium across the plasma membrane of most cells. Research carried out during the last couple of decades has led to a dramatic change in this simplistic view. We now know that most animal cells, neurons included, exhibit a non-equilibrium distribution of Cl- across their plasma membranes. Over the last 10 to 15 years, with the growth of molecular biology and the advent of new optical methods, an enormous amount of exciting new information has become available on the molecular structure and function of Cl- channels and carriers. In nerve cells, Cl- channels and carriers play key functional roles in GABA- and glycine-mediated synaptic inhibition, neuronal growth and development, extracellular potassium scavenging, sensory-transduction, neurotransmitter uptake and cell volume control. Disruption of Cl- homeostasis in neurons underlies pathological conditions such as epilepsy, deafness, imbalance, brain edema and ischemia, pain and neurogenic inflammation. This book is about how chloride ions are regulated and how they cross the plasma membrane of neurons. It spans from molecular structure and function of carriers and channels involved in Cl- transport to their role in various diseases.
* The first comprehensive book on the structure, molecular biology, cell physiology, and role in diseases of chloride transporters / channels in the nervous system in almost 20 years
* Chloride is the most abundant free anion in animal cells. THis book summarizes and integrates for the first time the important research of the past two decades that has shown that Cl- channels and carriers play key functional roles in GABA- and glycine-mediated synaptic inhibition, neuronal growth and development, extracellular potassium scavenging, sensory-transduction, neurotransmitter uptake and cell volume control.
* The first book that systematically discusses the result of disruption of Cl- homeostasis in neurons which underlies pathological conditions such as epilepsy, deafness, imbalance, brain edema and ischemia, pain and neurogenic inflammation.
* Spanning topics from molecular structure and function of carriers and channels involved in Cl- transport to their role in various diseases.
* Involves all of the leading researchers in the field.
* INcludes an extensive introductory section that covers basic thermodynamic and kinetics aspects of Cl- transport, as well as current methods for studying Cl- regulation, spanning from fluorescent dyes in single cells to knock-out models to make the book available for a growing population of graduate students and postdocs entering the field.

Attention, Volume 176 (Hardcover, 176th edition): Narayanan Srinivasan Attention, Volume 176 (Hardcover, 176th edition)
Narayanan Srinivasan
R6,565 Discovery Miles 65 650 Ships in 10 - 15 working days

This well-established international series examines major areas of basic and clinical research within neuroscience, as well as emerging and promising subfields.

This volume explores interdisciplinary research on Attention and interaction of Attention with other cognitive processes including perception, learning, and memory. The papers cover major research on attention in Cognitive Neuroscience and Cognitive Psychology. The volume presents recent advances on attention including binding, dynamics of attention, attention and perceptual organization, attention and consciousness, emotion and attention, development of attention, crossmodal attention, computational modeling of attention, control of actions, attention and memory, and meditation.

Fixed/Mobile Convergence and Beyond - Unbounded Mobile Communications (Paperback): Richard Watson Fixed/Mobile Convergence and Beyond - Unbounded Mobile Communications (Paperback)
Richard Watson
R1,501 Discovery Miles 15 010 Ships in 10 - 15 working days

Mobile communications users are demanding increased reliability, functionality, and accessibility; they want "always on" access to voice, e-mail, text, and multimedia services as they roam from home to auto to office to outdoor/indoor locations. In addition, there is an increasing deamnd to replace separate landline/mobile telephones with a single handset that can be used wherever its owner might be. Answering those customer needs, fixed/mobile convergence (FMC) marries the mobility provided by cellular networks with the extended connectivity provided by 802.11-based WiFi services and integrates them with landline networks using a single handset. This book provides the theoretical and practical background necessary to successfully plan, develop, and deploy effective FMC networks.
This book discusses the various 802.11 and VoIP protocols used in FMC networks, open and proprietary communications protocols, integration of FMC networks to wired telephone networks, mobilizing applications such as text messaging and video, security issues, mobile handset requirements for FMC networks, and the administration/management of FMC networks. Special attention is given to selecting appropriate components for FMC, and numerous case histories and examples from the author's experience are provided.
This book is an essential tutorial and reference for any RF/wireless, communications, and networking professional who will work with the next generation of wireless networks.
CONTENTS:
Chapter 1 Unbounded Mobile Communications
Chapter 2 Mobile Communications - State of the Technology
Chapter 3 Unbounded Mobile Communications - what is it?
Chapter 4 UMC - an overview of the technologyrequirements & considerations
Chapter 5 UMC - Current Market Solution Overview
Chapter 6 UMC - Layer 1 & 2 - Media requirements
Chapter 7 VoIP - Layer 3 & 4, the IP infrastructure
Chapter 8 Voice Optimized Networks - the network orphan
Chapter 9 Mobile Handset Solutions
Chapter 10 Hotspot & Hotzone Access
Chapter 11 Security considerations
Chapter 12 PBX features & integration
Chapter 13 UMC Management and Statute conformance considerations
Chapter 14 Mobilizing applications
Chapter 15 The Final Challenge - Sales/support channel considerations
Chapter 16 Unbounded mobile communications - beyond FMC
Glossary
KEY FEATURES
* Describes how to develop, deploy, and manage networks that seamlessly combine landline, cellular, and WiFi networks into one converged communications network.
* Thorough coverage of various 802.11 and voice over internet protocol (VoIP) standards and how they impact integration with cellular networks.
* Discusses security considerations and how to successfully manage converged networks.
* Includes numerous case histories and examples from the author's experience---this is not a purely theoretical treatment of the subject!

Animal and Translational Models for CNS Drug Discovery: Neurological Disorders (Hardcover): Robert A. McArthur, Franco Borsini Animal and Translational Models for CNS Drug Discovery: Neurological Disorders (Hardcover)
Robert A. McArthur, Franco Borsini
R1,698 Discovery Miles 16 980 Ships in 10 - 15 working days

"Neurological Disorders" is written for researchers in both academia and the pharmaceutical industry who use animal models in research and development of drugs for neurological disorders such as neurofibromatosis, Alzheimer s disease, Parkinson s disease, Huntington disease, ALS, and the epilepsies. "Neurological Disorders "has introductory chapters expressing the view of the role and relevance of animal models for drug discovery and development for the treatment of psychiatric disorders from the perspective of (a) academic basic neuroscientific research, (b) applied pharmaceutical drug discovery and development, and (c) issues of clinical trial design and regulatory agencies limitations. Each volume examines the rationale, use, robustness and limitations of animal models in each therapeutic area covered and discuss the use of animal models for target identification and validation. The clinical relevance of animal models is discussed in terms of major limitations in cross-species comparisons, clinical trial design of drug candidates, and how clinical trial endpoints could be improved. The aim of this series of volumes on "Animal and Translational Models for CNS Drug Discovery" is to identify and provide common endpoints between species that can serve to inform both the clinic and the bench with the information needed to accelerate clinically-effective CNS drug discovery.

This is the second volume in the three volume-set, "Animal and Translational Models for CNS Drug Discovery" 978-0-12-373861-5, which is also available for purchase individually.
- Clinical, academic, government and industry perspectives fostering integrated communication between principle participants at all stages of the drug discovery process
- Critical evaluation of animal and translational models improving transition from drug discovery and clinical development
- Emphasis on what results mean to the overall drug discovery process
- Exploration of issues in clinical trial design and conductance in each therapeutic area"

Animal and Translational Models for CNS Drug Discovery: Psychiatric Disorders (Hardcover): Robert A. McArthur, Franco Borsini Animal and Translational Models for CNS Drug Discovery: Psychiatric Disorders (Hardcover)
Robert A. McArthur, Franco Borsini
R1,910 Discovery Miles 19 100 Ships in 10 - 15 working days

"Psychiatric Disorders" is written for researchers in both academia and the pharmaceutical industry who use animal models in research and development of drugs for psychiatric disorders such as anxiety, obsessive-compulsive disorder, depression, schizophrenia, bipolar disorder, ADHD, and autistic spectrum disorder. "Psychiatric Disorders "has introductory chapters expressing the view of the role and relevance of animal models for drug discovery and development for the treatment of psychiatric disorders from the perspective of (a) academic basic neuroscientific research, (b) applied pharmaceutical drug discovery and development, and (c) issues of clinical trial design and regulatory agencies limitations. Each volume examines the rationale, use, robustness and limitations of animal models in each therapeutic area covered and discuss the use of animal models for target identification and validation. The clinical relevance of animal models is discussed in terms of major limitations in cross-species comparisons, clinical trial design of drug candidates, and how clinical trial endpoints could be improved. The aim of this series of volumes on "Animal and Translational Models for CNS Drug Discovery" is to identify and provide common endpoints between species that can serve to inform both the clinic and the bench with the information needed to accelerate clinically-effective CNS drug discovery.

This is the first volume in the three volume-set, "Animal and Translational Models for CNS Drug Discovery" 978-0-12-373861-5, andis also available for purchase individually.
Provides clinical, academic, government and industry perspectives fostering integrated communication between principle participants at all stages of the drug discovery processCritical evaluation of animal and translational models improving transition from drug discovery and clinical developmentEmphasizes what results mean to the overall drug discovery processExplores issues in clinical trial design and conductance in each therapeutic areaPsychiatric Disorders is available for purchase individually."

Advances in Imaging and Electron Physics, Volume 155 - Selected Problems of Computational Charged Particle Optics (Hardcover,... Advances in Imaging and Electron Physics, Volume 155 - Selected Problems of Computational Charged Particle Optics (Hardcover, 155th edition)
Dmitry Greenfield, Mikhael Monastyrskii; Series edited by Peter W. Hawkes
R5,272 Discovery Miles 52 720 Ships in 10 - 15 working days

"Advances in Imaging and Electron Physics" merges two long-running serials--"Advances in Electronics and Electron Physics" and "Advances in Optical and Electron Microscopy." This series features extended articles on the physics of electron devices (especially semiconductor devices), particle optics at high and low energies, microlithography, image science and digital image processing, electromagnetic wave propagation, electron microscopy, and the computing methods used in all these domains.
This monograph summarizes the authors' knowledge and experience acquired over many years in their work on computational charged particle optics. Its main message is that even in this era of powerful computers with a multitude of general-purpose and problem-oriented programs, asymptotic analysis based on perturbation theory remains one of the most effective tools to penetrate deeply into the essence of the problem in question.

Advances in Imaging and Electron Physics, Volume 158 (Hardcover, 158th edition): Peter W. Hawkes Advances in Imaging and Electron Physics, Volume 158 (Hardcover, 158th edition)
Peter W. Hawkes
R5,567 Discovery Miles 55 670 Ships in 10 - 15 working days

Advances in Imaging and Electron Physics merges two long-running serials--Advances in Electronics and Electron Physics and Advances in Optical and Electron Microscopy. This series features extended articles on the physics of electron devices (especially semiconductor devices), particle optics at high and low energies, microlithography, image science and digital image processing, electromagnetic wave propagation, electron microscopy, and the computing methods used in all these domains.

Updated with contributions from leading international scholars and industry experts
Discusses hot topic areas and presents current and future research trends
Provides an invaluable reference and guide for physicists, engineers and mathematicians

Mind and Motion: The Bidirectional Link between Thought and Action, Volume 174 - Progress in Brain Research (Hardcover, 174th... Mind and Motion: The Bidirectional Link between Thought and Action, Volume 174 - Progress in Brain Research (Hardcover, 174th edition)
Markus Raab, Joseph Johnson, Hauke Heekeren
R6,957 Discovery Miles 69 570 Ships in 10 - 15 working days

This volume investigates the implications of how our brain directs our movements on decision making. An extensive body of knowledge in chapters from international experts is presented as well as integrative group reports discussing new directions for future research.
The understanding of how people make decisions is of central interest to experts working in fields such as psychology, economics, movement science, cognitive neuroscience, neuroinformatics, robotics, and sport science. For the first time the current volume provides a multidisciplinary overview of how action and cognition are integrated in the planning of and decisions about action.
* Offers intense, focused, and genuine interdisciplinary perspective
* Conveys state-of-the-art and outlines future research directions on the hot topic of mind and motion (or embodied cognition)
* Includes contributions from psychologists, neuroscientists, movement scientists, economists, and others

FRET and FLIM Techniques, Volume 33 (Paperback): Theodorus W J Gadella FRET and FLIM Techniques, Volume 33 (Paperback)
Theodorus W J Gadella
R2,116 Discovery Miles 21 160 Ships in 10 - 15 working days

This volume reviews the techniques Forster Resonance Energy Transfer (FRET) and Fluorescence Lifetime Imaging Microscopy (FLIM) providing researchers with step by step protocols and handy hints and tips. Both have become staple techniques in many biological and biophysical fields.

Handbook of Reward and Decision Making (Hardcover): Jean-Claude Dreher, Leon Tremblay Handbook of Reward and Decision Making (Hardcover)
Jean-Claude Dreher, Leon Tremblay
R3,647 R3,301 Discovery Miles 33 010 Save R346 (9%) Ships in 10 - 15 working days

This book addresses a fundamental question about the nature of behavior: how does the brain process reward and makes decisions when facing multiple options? The book presents the most recent and compelling lesion, neuroimaging, electrophysiological and computational studies, in combination with hormonal and genetic studies, which have led to a clearer understanding of neural mechanisms behind reward and decision making. The neural bases of reward and decision making processes are of great interest to scientists because of the fundamental role of reward in a number of behavioral processes (such as motivation, learning and cognition) and because of their theoretical and clinical implications for understanding dysfunctions of the dopaminergic system in several neurological and psychiatric disorders (schizophrenia, Parkinson's disease, drug addiction, pathological gambling, ...).

* Comprehensive coverage of approaches to studying reward and decision making, including primate neurophysiology and brain imaging studies in healthy humans and in various disorders, genetic and hormonal influences on the reward system and computational models.

* Covers clinical implications of process dysfunction (e.g., schizophrenia, Parkinson's disease, eating disorders, drug addiction, pathological gambling)

* Uses multiple levels of analysis, from molecular mechanisms to neural systems dynamics and computational models.

" "This is a very interesting and authoritative handbook by some of the most outstanding investigators in the field of reward and decision making "," Professor Edmund T. Rolls, Oxford Center for Computational Neuroscience, UK

Hormone/Behavior Relations of Clinical Importance - Endocrine Systems Interacting with Brain and Behavior (Hardcover, New):... Hormone/Behavior Relations of Clinical Importance - Endocrine Systems Interacting with Brain and Behavior (Hardcover, New)
Robert H. Rubin, Donald W. Pfaff
R4,393 Discovery Miles 43 930 Ships in 10 - 15 working days

A single volume of 41 articles, Hormone/Behavior Relations of Clinical Importance is an authoritative selection of relevant chapters from the Hormones Brain and Behavior 2e MRW, the most comprehensive source of neuroendocrinological information assembled to date (AP July 2009).
The study of hormones as they impact the brain and, subsequently, behavior is a central topic in neuroscience, endocrinology and psychiatry. This volume offers an overview of neuroendocrinological topics, approaching the subject from the perspective of hormone-brain function, hormone-behavior relations, sex differences, and the impact on various diseases/pathologies. Many basic human behavioral functions are subject to the influence of hormones - sexual orientation, the experience of pain, fertility, immunity - as are clinical conditions such as diabetes, substance abuse disorder, eating disorders, PTSD, TBI, pain, Alzheimer's, stress/anxiety, affective disorders, and more. There is considerable commercial clinical potential in the study of hormones - drug companies are currently developing a Cholecystokinin (hormonal peptide) booster to reduce appetite in those who suffer from sever obesity, and catamenial epilepsy (features seizure exacerbation in relation to the menstrual cycle) is resistant to treatment by standard antiepileptic medications, but may be hormonally controlled. These issues and more are covered, and there is simply no other current single-volume reference with such comprehensive coverage and depth.
Authors selected are the internationally renowned experts for the particular topics on which they write, and the volume is richly illustrated with over 150 figures (50 in color). A collection of articles reviewing our fundamental knowledge of neuroendocrinology, the book provides an essential, affordable reference for researchers, clinicians and graduate students in the area.
- Offering outstanding scholarship, each chapter is written by an expert in the topic area and approximately 25% of chapters are written by international contributors (7 countries represented)
- Provides more fully vetted expert knowledge than any existing work with broad appeal for the US, UK and Europe, accurately crediting the contributions to research in those regions
- Heavily illustrated with 150 figures, approximately 50 in color, presenting the material in the most visually useful form for the reader
- Fully explores various clinical conditions associated with the hormones and the brain (PTSD, TBI, Stress & Anxiety, eating disorders, diabetes, addictive disorders, Alzheimer's, affective disorders)
- Broad coverage of disorders makes the volume relevant to clinicians as well as researchers and basic scientists

Embedded Systems and Software Validation (Hardcover): Abhik Roychoudhury Embedded Systems and Software Validation (Hardcover)
Abhik Roychoudhury
R1,712 Discovery Miles 17 120 Ships in 10 - 15 working days

Modern embedded systems require high performance, low cost and low power consumption. Such systems typically consist of a heterogeneous collection of processors, specialized memory subsystems, and partially programmable or fixed-function components. This heterogeneity, coupled with issues such as hardware/software partitioning, mapping, scheduling, etc., leads to a large number of design possibilities, making performance debugging and validation of such systems a difficult problem.

Embedded systems are used to control safety critical applications such as flight control, automotive electronics and healthcare monitoring. Clearly, developing reliable software/systems for such applications is of utmost importance. This book describes a host of debugging and verification methods which can help to achieve this goal.
Covers the major abstraction levels of embedded systems design, starting from software analysis and micro-architectural modeling, to modeling of resource sharing and communication at the system levelIntegrates formal techniques of validation for hardware/software with debugging and validation of embedded system design flowsIncludes practical case studies to answer the questions: does a design meet its requirements, if not, then which parts of the system are responsible for the violation, and once they are identified, then how should the design be suitably modified?

Semiconductors and the Information Revolution - Magic Crystals that made IT Happen (Paperback): John W. Orton Semiconductors and the Information Revolution - Magic Crystals that made IT Happen (Paperback)
John W. Orton
R687 Discovery Miles 6 870 Ships in 10 - 15 working days

This book sets out to explain the development of modern electronic systems and devices from the viewpoint of the semiconductor materials (germanium, silicon, gallium arsenide and many others) which made them possible. It covers the scientific understanding of these materials and its intimate relationship with their technology and many applications. It began with Michael Faraday, took off in a big way with the invention of the transistor at Bell Labs in 1947 and is still burgeoning today. It is a story to match any artistic or engineering achievement of man and this is the first time it has been presented in a style suited to the non-specialist. It is written in a lively, non-mathematical style which brings out the excitement of discovery and the fascinating interplay between the demands of system pull and technological push. It also looks at the nature of some of the personal interactions which helped to shape the modern technological world.
An introductory chapter illustrates just how dependent we are on modern electronic systems and explains the significance of semiconductors in their development. It also provides, in as painless a way as possible, a necessary understanding of semiconductor properties in relation to these applications. The second chapter takes up the historical account and ends with some important results emerging from the Second World War including its effect on the organisation of scientific research. Chapter three describes the world-shaking discovery of the transistor and some of the early struggles to make it commercially viable, including the marketing of the first transistor radio. In chapter four we meet the integrated circuit which gave shape to much of our modern life in the form of the personal computer (and which gave rise to a famously long-running patent war ). Later chapters cover the application of compound semiconductors to light-emitting devices, such as LEDs and lasers, and light detecting devices such as photocells. We learn how these developments led to the invention of the CD player and DVD recorder, how other materials were applied to the development of sophisticated night vision equipment, fibre optical communications systems, solar photovoltaic panels and flat panel displays. Similarly, microwave techniques essential to our modern day love of mobile phoning are seen to depend on clever materials scientists who, not for the first time, "invented" new semiconductors with just the right properties.
Altogether, it is an amazing story and one which deserves to be more widely known. Read this book and you will be rewarded with a much deeper understanding and appreciation of the technological revolution which shapes so many aspects of our lives.
- A historical account of the development of semiconductor physics, devices and applications from the nineteenth century to the present day
- Coverage of the importance of material quality and its relation to the physics of the devices
- Presented in a strictly non-mathematical and anecedotal way, to appeal to a wide audience
- Provides the broad sweep of science history"

Zigbee Wireless Networking (Paperback): Drew Gislason Zigbee Wireless Networking (Paperback)
Drew Gislason
R1,451 Discovery Miles 14 510 Ships in 10 - 15 working days

ZigBee is a standard based on the IEEE 802.15.4 standard for wireless personal networks. This standard allows for the creation of very lost cost and low power networks - these applications run for years rather than months. These networks are created from sensors and actuators and can wireless control many electrical products such as remote controls, medical, industrial, and security sensors.
Hundreds of companies are creating applications including Mitsubishi, Motorola, Freescale, and Siemens. This book is written for engineers who plan to develop ZigBee applications and networks, to understand how they work, and to evaluate this technology to see if it is appropriate to a particular project. This book does not simply state facts but explains what ZigBee can do through detailed code examples.
CONTENTS:
CHAPTER 1 HELLO ZIGBEE
CHAPTER 2 DECIDING ON ZIGBEE
CHAPTER 3 THE ZIGBEE DEVELOPMENT ENVIRONMENT
CHAPTER 4 ZIGBEE APPLICATIONS
CHAPTER 5 ZIGBEE, ZDO AND ZDP
CHAPTER 6 THE ZIGBEE CLUSTER LIBRARY
CHAPTER 7 THE ZIGBEE NETWORKING LAYER
CHAPTER 8 COMMISSIONING ZIGBEE NETWORKS
CHAPTER 9 ZIGBEE GATEWAYS
APPENDIX A ZIGBEE 2007 AND ZIGBEE PRO
APPENDIX B ZIGBEE QUICK REFERENCE
APPENDIX C ZIGBEE CLUSTER LIBRARY QUICK REFERENCE
*Details how to plan and develop applications and networks
*Zigbee sensors have many applications including industrial automation, medical sensing, remote controls, and security
*Hot topic for today's electrical engineer because it is low cost and low power

Antarctic Climate Evolution (Hardcover): Fabio Florindo, Martin Siegert Antarctic Climate Evolution (Hardcover)
Fabio Florindo, Martin Siegert
R3,328 Discovery Miles 33 280 Ships in 10 - 15 working days

This is the first book dedicated to the developing knowledge on how the world's largest ice sheet formed and changed over its 34 million years history. In explaining the story of Antartica, information on terrestrial and marine geology, sedimentology, glacier geophysics (including airborne reconnaissance), shipborne geophysics, and numerical ice sheet and climate modelling, will be interwoven within eleven chapters, each deling with an important historical theme. The approach will be to first 'set the scene', involving chapters dedicated to how ice sheets and their glacial history can be measured. This opening section will provide information necessary to comprehend the latter section of the book, in which five chapters will related the glacial and climate evolution of Antartica during the most important time-frames in which changes have occurred.
* An overview of antarctic climate change, analysing historical, present day and future developments
* Contributions from leading experts and scholars from around the world
* Informs and updates climate change scientists and experts in related areas of study

Textbook of Nephro-Endocrinology (Hardcover): Ajay K Singh, Gordon H. Williams Textbook of Nephro-Endocrinology (Hardcover)
Ajay K Singh, Gordon H. Williams
R3,524 Discovery Miles 35 240 Ships in 10 - 15 working days

The Textbook of Nephro-Endocrinology is the definitive translational reference in the field of nephro-endocrinology, investigating both the endocrine functions of the kidneys and how the kidney acts as a target for hormones from other organ systems. It offers both researchers and clinicians expert, gold-standard analysis of nephro-endocrine research and translation into the treatment of diseases such as anemia, chronic kidney disease (CKD), rickets, osteoprosis, and, hypoparathyroidism.
* Investigates both the endocrine functions of the kidneys and how the kidney acts as a target for hormones from other organ systems.
* Presents a uniquely comprehensive and cross-disciplinary look at all aspects of nephro-endocrine disorders in one reference work.
* Clear translational presentations by the top endocrinologists and nephrologists in each specific hormone or functional/systems field.

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