Urological oncology constitutes 20% of all malignant disease, and includes renal, bladder, prostate and testicular cancer. This is an area of medical and scientific interest, where advances in clinical practice and translational research have led to significant changes in the way that patients are managed.

The book summarizes developments in all areas of urological cancer including clinical and molecular advances. The aim of the book is to educate urologists and oncologists so that they are able to understand scientific developments within urological oncology and be up to date with clinical practice in this area. The book includes within its ambit both guidelines for clinical practice and synopses of advances in science research.

This practical handbook provides a distillation of current practice and research for oncologists and urologists in clinical practice.

The first edition of Male Sexual Function: A Guide to Clinical Management was published in 2001. Since that time, two new oral medications for erectile dysfunction (R) (R) (ED), Vardenafil (Levitra ) and Tadalafil (Cialis ), have been introduced. Links between ED and lower urinary tract symptoms have been postulated, advances in the basic science of erectile physiology have occurred, and the appreciation of ED as a form of endothelial dysfunction and a harbinger of other more potentially lethal forms of vascular disease has become more widespread. In some instances, third-party payers have reduced or eliminated coverage for ED treatments in an attempt to cut costs. They have classified sexual activity as "recreational," "lifestyle," or not medically necessary, but have failed to appreciate the negative consequences of ED, such as depression with all of its ramifications. Male Sexual Function: A Guide to Clinical Management, Second Edition is a comp- hensive overview of the field of male sexual function and includes a chapter on female sexual dysfunction, an emerging field with a very high incidence in the population and an ever-growing following.

A comprehensive reference, drawing on the expertise of international leaders in the field, this text covers everything from epidemiology, pathology, and diagnosis to the treatment of both superficial and invasive bladder cancers . The book contains over 300 to quality illustrations.

Urological Emergencies in Clinical Practice summarizes adult and paediatric urological emergencies and their management - diagnosis and treatment, in a concise, relevant and readily available form. Signs and symptoms are listed and specific treatments explained. This is a simple yet practical guide to the management of urological emergencies with an emphasis on common urological emergencies seen in everyday practice. Any clinician without previous urological knowledge will be able to make an accurate diagnosis and have a treatment plan to follow. A user-friendly pocketbook, this is easy to refer to in an emergency situation. Each chapter is clearly marked, separated and organised into sections with Heading of signs, symptoms, diagnosis and management placed in a numbered fashion similar to an Objective structured clinical examination. Some sections also have useful hints and tips. Covering the basics of treatment rather than going into depth, these small but very important aspects of care are usually not mentioned in big reference textbooks, yet form an important aspect in everyday life. Aimed at residents in Urology, it will also be useful to Accident and Emergency doctors and P

Aging is associated with morphologic and functional alterations of organ systems including the genitourinary tract. Aging of the bladder leads to urgency, frequency, dysuria, recurrent urinary tract infections and incontinence both in the aging men and women. These symptoms occur frequently, are very distressing and influence daily life of the aging person. Besides patients symptoms, medications and incontinence devices are a tremendous financial burden on health care systems. Understanding the morphologic and functional processes of the aging bladder may decrease symptoms, costs and develop new, preventive strategies for the treatment of the aging bladder. This book reviews present knowledge of morphologic and functional alterations of the aging bladder both in men and women adding new insights in order to optimize therapeutic options for the treatment of aging bladder in daily practice and improve patients quality of life.

This is the only book entirely devoted to the sensory circumventricular organs. It reviews research into their detailed anatomy, neurochemistry, neural connections, and functions, and provides the reader with many illustrations previously unpublished.

The alternation between urine retention and discharge several times daily from a nappy to the cessation ofall vital functions only becomes the subject baby's first wet of greater attention if the harmony of the structure and function of the bladder is disturbed. Functional disturbances of the lower urinary tract are not only of great socio-economic importance, but are also a considerable personal burden for the patient. Hence urinary incontinence is rightly classified as a severelydisabling illness (Hauri 1985). Opinions still differ regarding the morphological basis ofurinary continence.The Terminologia Anatomica (1998) defines a musculus sphincter urethrae internus (in- ternal urethral sphincter) and a musculus sphincter urethrae externus (external ure- thral sphincter),which in the older nomenclature were known as musculus sphincter vesicae and musculussphincterurethrae,respectively.The internal urethral sphincter isascribed apurelyinvoluntaryandthe externalurethralsphincterapurelyvoluntary innervation. The significance of the musculature of the pelvic floor for maintaining urinarycontinence has notyetbeen ascertained. Duringnumerous urologicaloperations (forinstancetransurethralresectionofthe prostate and bladder neck incisions), the only involuntarily innervated sphincter at the collum vesicae,the internalurethralsphincter,is partiallyorcompletelydestroyed (Fig. 27C,D).All the patients remain continent as long as the externalurethral sphinc- ter remains intact.Howcan apurelyvoluntarilyinnervated sphincterlikethe external urethral sphincter ensureconstant continence in such cases? Improving the continence rate after radical surgery is a key topic of urological research. The incontinence rate after radical prostatectomy is still between 8.1% (third-degree incontinence) and41.4% (first- to second-degree incontinence; Rudyet al. 1984; Igel et a1.1987; Schroderand Ouden 1992).

The 1973 WHO classification of bladder tumours anticipated a probable need for eventual revision of the criteria for diagnosing papillary and flat bladder neoplasia. A workshop sponsored by the WHO consisting of pathologists, urologists, cytologists, oncologists and basic scientists interested in bladder tumours addressed this subject, and after a follow- -up meeting sponsored by the International Society of Urological Pathology, the classification and terminology used in this text were agreed upon. A major change is in the introduction of a new category: papillary urothelial neoplasm of low malignant potential. Many of the tumours previously designated as papillary transitional cell carcinoma, grade I now fall into that category. Another major change is in the designation of flat lesions, and this includes a definition of carcinoma in situ. Furthermore, a number of variant forms of urothelials carcinomas are included as well as new entities not recognized when the 1st edition was issued.

Pediatric and Adolescent Urologic Imaging provides a comprehensive reference for health care providers of children and adolescents with urologic conditions. This is the first book in which each chapter is written collaboratively by at least one author from each specialty. This unique approach melds the expertise of each specialist and offers it to the reader in a manner aimed at reinforcing the integration of clinical information to radiologic imaging. The book is arranged into two sections allowing for easy access to the information. The first section covers the principles of each radiologic modality as well as radiation safety and the history of uroradiology. The second section integrates the lessons of the first section into specific urologic conditions arranged anatomically and includes additional unique conditions. Pediatric and Adolescent Urologic Imaging is a key reference for pediatric urologists and radiologists as well as primary care providers, general urologists and radiologists, fellows, residents, medical students, and mid-level providers.

Ureteroceles: Contemporary Diagnosis and Management provides an evidence-based review of current diagnosis and management options for patients with ureteroceles. With the advent of antenatal ultrasound screening, ureteroceles are presenting earlier, often in asymptomatic patients, proving the need for active surveillance. With no fixed protocols and guidelines currently in the field, this important reference brings together recent techniques, such as in utero puncture, endoscopic laser fenestration, and laparoscopic clipping of the upper moiety ureter. Case studies illustrate various diagnostic and management options. This important reference provides all the necessary resources for ureterocele diagnosis and management needed by urology researchers, pediatric urologists, and general surgeons.

Concise, thorough, and superbly illustrated, Atlas of Laparoscopic and Robotic Urologic Surgery, 4th Edition, is an ideal resource for learning new techniques or briefly reviewing before a case. Written and edited by renowned experts in the field of laparoscopic and robotic surgery, this practical text covers today's best minimally invasive approaches using the surgical systems, equipment, and robotic devices in use today. More than three hours of video instruction, an increased focus on robotics and new urologic procedures, and step-by-step illustrations help you sharpen your skills in this high-demand area. Contains new chapters on Post Operative Management: Pain and Other Considerations for Enhanced Recovery after Surgery (ERAS); Bladder Reconstruction in Children; Sacrocolpopexy; Applications for Infertility Surgeries; and Surgery of the Spermatic Cord. Includes new and updated information on nephrectomy, adrenalectomy and partial adrenalectomy, urinary diversion, and partial cystectomy and diverticulectomy. Offers new content on camera and lens systems, instrumentation, the da Vinci surgical system, pyelo/ureterolithotomy, robotic-assisted and laparoscopic simple prostatectomy, and more. Covers radical robotic prostatectomy, innovative approaches to treat ureteral strictures, up-to-date surgical care of malignancies, and novel pediatric surgeries. Features more than 30 high-quality videos online (many are new) including robotic retroperitoneal lymph node dissection, robotic assisted kidney transplantation, robotic simple prostatectomy, robotic cystectomy and robotic neobladder evolution, laparoscopic partial adrenalectomy, and many more. Provides clinical pearls, tips and tricks, and complications boxes throughout. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

This book contains a compilation of papers based on pres entations made at the International Symposium on Penile Disorders held in Hamburg, Germany, 26-27 January 1996, under the Chairmanship of Hartmut Porst. This was a unique conference in that it comprehensively addressed various disorders that affect the organ situated at the "center of the male," the penis. As an important beginning, the sociocultural aspects of the erect phallus were presented by G. Wagner from Copen hagen. The anatomy of the penis and the physiological con ditions of erection were then discussed by K. -P. J Unemann from Mannheim, Germany. Previous conferences on the penis had concentrated only on specific areas of disease such as impotence. However, it became readily apparent that at this conference something new for almost every as pect of disease would be discussed, including congenital disorders such as hypospadias and epispadias, sexually transmitted and noninfectious dermatological diseases, and congenital and acquired penile curvatures and penile fractures. An excellent presentation of managing penile cancer by stage related therapeutic decision was presented by S. C. MUller from Bonn, Germany. There is no better per son to present a discussion of Peyronie' s disease in 1996 from a historical and management perspective than J. Pryor from London, UK. This same degree of expertise was also demonstrated by I. Saenz de Tejada from Madrid, Spain, re garding priapism."

This classification is based primarily on the presence of morpho- logically identifiable cell types and growth patterns that can be correlated with the clinical behaviour of the tumour and, in some cases, with tumour markers in the serum. Although some of the histological terms and definitions have histogenetic impli- cations, this classification is not meant to be histogenetic. The terminology adopted for individual tumours is based on their general acceptance and world-wide usage. Synonyms are includ- ed only if they have been widely used in the literature or if they are considered helpful in understanding the lesions. Controver- sial histogenetic terms have been avoided whenever possible. The term tumour is used synonymously with neoplasm. The term tumour-like is applied to non-neoplastic lesions which clin- ically or morphologically resemble neoplasms; they are included in this classification because of their importance in differential diagnosis. Because of the many similarities between testis tumours and those of the ovary, an attempt has been made to follow the WHO histological typing of ovarian tumours. Histological Classification of Testis Tumours 1 Germ Cell Tumours 1.1 Precursor lesions - intra tubular malignant germ cells 1.2 Tumours of one histological type (pure forms) 1 1.2.1 Seminoma ...906113 1.2.1.1 Variant - Seminoma with syncytiotrophob- stic cells 1.2.2 Spermatocytic seminoma ...9063/3 1.2.2.1 Variant - Spermatocytic seminoma with sarcoma 1.2.3 Embryonal carcinoma ...9070/3 1.2.4 Yolk sac tumour ...907113 Polyembryoma ...

This is the first revision book to be published specifically for candidates sitting the FRCS(Urol) examination, which tests the required standard of a recognised Urology specialist. It provides a selection of common clinical scenarios together with a guide to answering the FRCS(Urol) questions. Each chapter is written by Consultant Urological Surgeons or Senior Urology Trainees who have already been successful in passing the examination. This second edition responds to continual changes in practice: The chapters on urological cancers including prostate cancer, bladder cancer and renal cancer have important updates due to emergence of new evidence and changes in NICE, EAU and AUA guidelines. Substantial revisions to other sections such as paediatric urology, female urology, urinary stone disease, benign prostatic hyperplasia and uro-technology to meet standards of current best practice. Adds an extra chapter on the TNM classification of urological cancers. The book remains an invaluable revision tool for the FRCS(Urol) and will also be useful for individuals sitting the FEBU and equivalent postgraduate urological examinations in the USA, Australia and Asia. Established consultants will also find value in the text as a 'refresher' in areas outside their subspecialist interest.

There is now increasing awareness by the general public in European countries that prostate cancer is a serious threat to health, and this has created higher expectations for improved and more effective methods for detecting and treating the disease. However, urologists are very conscious of the limitations of the diagnostic methods that are available and are even more concerned about the apparent lack of therapeutic advances made during the past 50 years since Huggins discovered the fundamental principles of endocrine treatment for is theo prostate cancer. Recent efforts to detect the disease when it retically "curable" have been successful, certainly in the USA, but this has highlighted our uncertainty about the best treatment for early stage prostate cancer, and there is no doubt that radical pro statectomy is sometimes carried out on men who may not be threa tened by their illness. While it is generally accepted that many men with prostate cancer will die of old age rather than this malignancy, it cannot be ignored that this disease kills many others in a process that is frequently lingering, miserable, and humiliating, not only for the victim but also his family. There are many important issues about prostate cancer that remain unclear at the present time, some of which are addressed by the reviews in this book. The debate about early detection and screening can arouse considerable heat in otherwise placid urological mee tings."

Cryptorchidism remains a common but poorly understood anomaly affecting 2%-5% of children. Major controversies exist over the timing and type of treat ment (i. e. surgical vs hormonal therapy) and whether intervention prevents sub sequent infertility and testicular cancer. Part of the dilemma is caused by lack of understanding of the normal process of descent, despite intensive research and study since the eighteenth century, when Hunter and von Haller first described the gubernaculum (caudal genito-inguinal ligament) and processus vaginalis (Williams and Hutson 1991a). More needs to be known, not only of the normal mechanism, but also of the ways that it can be deranged to produce undescended testes. This review describes the recent results of studies on normal descent, with emphasis on our studies of the different stages of descent. As the reader will appreciate, the ever-more complex models proposed to account for normal tes ticular descent predict that undescended testes will be caused by a multitude of anomalies affecting different stages of the process. A description is given of current hypotheses of the aetiology of cryptorchidism, correlating these with studies of cryptorchid animal models. For a more detailed description of the numerous ideas about the mechanism, the reader is referred to Heyns and Hutson (1995) and other monographs (Fonkalsrud and Mengel 1981; Abney and Keel 1989)."

Erectile dysfunction is a complex syndrome associated and determined by several separate vascular and nonvascular factors. In recent years, the evolution of noninvasive vascular technology used to investigate macro- and microcirculation in vascular disorders has produced a large amount of information and increased our knowledge of vascular pathophysiology. Andrea Ledda and his clinical research group, well known to their international colleagues, describe new developments in andrology and stress the importance of vascular disorders in erectile dysfunction. This volume will be very useful to andrologists, vascular surgeons, and angiologists, and to all specialists interested in the diagnostic evaluation of erectile disorders and varicocele.

Fibrin sealant is used for numerous indications in gynecology, especially for the McIndoe Operation and Cohn biopsy, the Marshall-Marchetti-Krantz-Hirsch-Stoll-Operation, urethrocysopexy, or in vitro fertilization for embryo transfer. The use of fibrin sealant in urology has also been extended, especially in operations of the spermatic cord, reconstruction of the urethra and closing of nephrotomies.

Dr. Hans-Peter Schmid has addressed in this monograph the basic dilemmas surrounding prostate cancer. These dilemmas include the 40 % histologic incidence of invasive cancer in men in comparison to a 3 % death rate, the extraordinary slow doubling time of four to five years for untreated early clinical stages (T1 and T2 cancers), the limited life span of even healthy men over 70 years of age, and the national and international debates of how to treat this cancer. It is important, however, to recognize that despite these uncertainties, prostate cancer is probably the most predictive of all human solid tumors. Dr. Schmid has addressed the basis for much of this predictability in this monograph. The level of serum PSA and its rate of increase in the untreated patient with a prostate size of less than 50 grams is undoub tedly the most useful of all measurements in predicting volume and grade of the cancer, but it is closely followed by assessment of the extent and percent of grade 4 and 5 cancer in six systematic, spatially separated biopsies. Estimating the amount of suspected cancer on digital rectal examination by assigning a clinical stage is useful, but far less quantitative than PSA and systematic biopsies. The Basel series in this monograph adds strong support to these basic concepts. April 1994 ThomasA. Stamey, M. D. Professor and Chairman Department of Urology Stanford University School of Medicine Stanford, California, USA v Contents Preface. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . V I. 1 Introduction and overview . . . . . . . . . . . . . . . . . . . . . . . . . . ."

With mesh surgery for prolapse sometimes proving problematic, there has been a resurgence of professional medical interest in more traditional methods for the management of prolapse and of stress urinary incontinence. This concise guide to the practical aspects of pessary use will be of interest to all gynecologists involved in the clinical management of the patient with these problems. Contents: Historical review * Pessaries for pelvic organ prolapse * Incontinence pessaries * Pessary fitting * Pessary care * Outcomes of pessary use * Current clinical studies on vaginal pessaries Cover image of vaginal pessaries (c) 2019 Rick Hicaro, Jr., Chicago, IL 60647, USA

Divided into five sections focusing on perioperative, surgical, pediatric, endoscopic and laparoscopic, and miscellaneous complications, this guide supplies state-of-the-art strategies for the identification, prevention, and management of the myriad complications that can arise during urologic surgical treatment. With contributors from leading health centers across the United States, this source reviews the potential complications of the latest laparoscopic procedures, as well as those related to systemic conditions.

From a renowned specialist at the Cleveland Clinic and medical and surgical experts in this growing field comes an up-to-date, multidisciplinary resource on transgender health care and surgery. Comprehensive Care of the Transgender Patient, by Dr. Cecile Unger, covers all aspects of transgender health care, beginning with epidemiology and history and progressing to an in-depth review of the complex transition for patients, including mental health services, endocrine and hormone therapy treatment, and surgical options. Incorporates all of the latest guidelines for providers and patients, written by experts from a wide variety of disciplines involved in transgender patient care. Contains outstanding surgical chapters contributed by prominent surgeons who regularly perform these procedures, providing clear guidance on male-to-female and female-to-male surgical options. Features high-quality, full-color illustrations throughout. Covers key topics in every area of transgender health care, including Mental Health Care for the Adult and for the Child and Adolescent Transgender Patient; Hormone Treatment for the Adult and Adolescent Transgender Patient; Facial Surgery for Transgender Patients; Breast and Genital Surgeries for Transgender Patients; and Primary, Preventive, and Gynecologic Care. Expert ConsultT eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, Q&As, and references from the book on a variety of devices.

Although impotence may be the most widely recognized manifestation of male sexual dysfunction, many other forms of sexual disorders do not involve the erectile mechanism, from deficiencies of desire to disturbances in ejaculatory function to the failure of detumescence. With such a myriad-and often co-existing-number of disorders, the successful treatment of male sexual dysfunction requires not only a thorough understanding of the underlying physiology and pathophysiology, but also the coordinated efforts of multiple specialties, including endocrinology, andrology, urology, radiology, sex therapy, and even sometimes psychiatry, cardiology, or oncology. Male Sexual Dysfunction: Pathophysiology and Treatment presents the collective expertise of more than 60 international authorities in a single landmark text. From foundations in the anatomy of the male genital tract to the latest neuroimaging data, readers will appreciate the comprehensive information detailing the tremendous advances made in the delineation of sexual function and its disorders as well as the expert descriptions of practical and cost-effective medical, surgical, and psychological strategies for the treatment of all forms of male sexual dysfunction.

Offering an authoritative collection of chapters from clinicians and researchers in the United States, Canada, and Europe, this reference comprehensively covers the latest understanding in the etiology, pathophysiology, diagnosis, and treatment of sexual dysfunction.