The past decade has been marked by the acceleration of our understanding of the molecular biology of cancer. Simultaneously, there have been increasing exigencies to diagnose, treat and follow cancer patients more economically. Biomarkers represent the marriage of science and economics. Biomarkers offer the potential to increase the precision of diagnosis, prognosis, and surveillance of urological malignancies. This issue presents the cutting-edge advances of biomarker technology to urologic oncology.

Prostate Cancer, Science and Clinical Practice, Second Edition, continues to be an important translational reference that bridges the gap between science and clinical medicine. It reviews the biological processes that can be implicated in the disease, reviews current treatments, highlights the pitfalls where relevant, and examines the scientific developments that might result in future treatments. Key chapters from the previous edition have been updated, and a plethora of new chapters describe new concepts of prostate cancer biology and newly developed therapeutics. Each chapter has been written by internationally recognized specialists on prostate cancer epidemiology, genetic susceptibility, cancer metastases, prostate physiology, proteomics, new therapeutics, and clinical trials.

The fourth edition of the Oxford Handbook of Urology has been fully updated to reflect the significant advances in medical and surgical opportunities since the previous edition, including pelvic laparoscopic and robotic surgery, new drugs in incontinence and male sexual health, and new laser devices for prostate surgery. Guidelines from the European Association of Urology, the American Association of Urology, and the British Association of Urology, as well as NICE, have all been updated to reflect the best evidence-based clinical practice. Featuring both additional and expanded topics, the new edition is up to date for use in everyday urological clinical practice, and now includes recent urological controversies such as the use of vaginal mesh, to offer the newest guidance to help with doctors' consultations with the patient. The handbook is a comprehensive and concise resource, spanning the whole field of urology in an easily digestible format, including the basics of patient assessment and investigations. Providing bite-sized topics with easily navigable sections and summary diagrams and photographs, it is a key source for quick reference during clinical duties in clinics, theatre, and A&E settings, whilst providing enough information for urology doctors taking the FRCS exam. The authors have a wide range of subspecialist interests, and have welcomed a brand new co-author to ensure coverage of the needs of junior doctors. The Oxford Handbook of Urology is an invaluable resource for junior urology doctors, A&E and general surgery doctors, urology ward and theatre nurses, and medical students.

The Guest Editors have assembled top key opinion leaders to provide current reviews on the multidisciplinary approach to the management of high-grade bladder cancer. Articles are devoted to fluorescence cystoscopy, confocal laser endomicroscopy, narrow band imaging; Novel therapeutic approaches for recurrent nonmuscle invasive bladder cancer; Trimodality therapy in bladder cancer; the data and the reality of perioperative chemotherapy in muscle invasive bladder cancer; radical transurethral resection alone, robotic or partial cystectomy or extended lymphadenectomy: Neoadjuvant paradigm for drug development in muscle invasive bladder cancer; Novel biomarkers to predict response and prognosis in localized bladder cancer; Immunotherapy in Advanced/Metastatic Urothelial Cancer ; and Adjuvant Chemotherapy in High Grade Upper Tract Urothelial Cancer.

Urologists were early adaptors of robotic assisted laparoscopy, and pediatric urology similarly led in incorporating the technology into the surgical armamentarium for treating even the smallest infants. And it is in that tradition that this issue of Urologic Clinics of North America surveys the journey from the earliest pure laparoscopic procedures to the most advanced reconstruction possible today due to evolutions in technology. The issue begins with the procedure that arguably popularized the laparoscopic approach in pediatric urology-the laparoscopic orchiopexy, then posit the continued relevance of pure laparoscopy in the robotic era, before finally surveying contemporary advances in robotic-assisted pediatric urologic surgery. The issue is of relevance not only tor the novice contemplating a transition to laparoscopy or robotics but also for the seasoned minimally invasive surgeon seeking to enhance skills and augment his or her practice.

Robotic-assisted laparoscopic urologic surgery is a major evolution in the field and has now become a major subspecialty. This issue of Urologic Clinics of North America aims to provide comprehensive, state-of-the-art information about the recent developments in the areas of Uro-Oncology, Reconstructive Urology, and Female Urology. Topics such as issue of training, evidence-based practice, the economics of robotic surgery, and the impact on public and global health are also covered.The contributors are truly pioneers and the best experts in the field.

The Year Book of Urology brings you abstracts of the articles that reported the year's breakthrough developments in urology, carefully selected from more than 500 journals worldwide. Expert commentaries evaluate the clinical importance of each article and discuss its application to your practice. There's no faster or easier way to stay informed! The Year Book of Urology is published annually in December.

Kidney anomalies are the most frequent abnormality detected on prenatal ultrasound. Some are inconsequential and others are life-threatening. All must be addressed by neonatologists. This edition of Pediatric Clinics of Perinatology covers these anomalies. In addition, it addresses a variety of other nephrology and urology issues that neonatologists confront. Some are rare and the chapter may then serve as an important resource. Others are common, and thus will provide updated information on diagnosis and management.

This issue of the Urologic Clinics will focus on urodynamic testing in men, women and special situations. Appropriate urodynamic testing options including video urodynamics, pressure flow studies, and neurogenic voiding discussion will be discussed. Dr. Nitti and Dr. Brucker have assembled well known experts in their fields to provide current clinical information for urodynamic evaluation, diagnosis, and treatment.

This issue of Ultrasound Clinics features a review of genitourinary topics and includes the following articles: Characterization of Renal Masses by Ultrasound; Renal Malignant Masses as Characterized by Ultrasound Contrast; US Elastography of Kidney; Prostate Biopsies and Controversies; Post-vasectomy Complications; Acute Scrotum; Testicular trauma- Role of Sonography; Testicular Elastography; Contrast Enhance Ultrasound of the testes; and Vascular Complications of Renal Transplant.

PSA screening remains highly controversial due to several important disadvantages. More PSA is produced with prostatic enlargement and in other benign conditions such as urinary tract infections. False positive tests can then lead to unnecessary diagnostic workup with invasive prostate biopsy. Another major problem with screening programs in general is overdiagnosis of cancers that would not have caused harm during the patient's lifetime. For example, many prostate cancers have a relatively indolent behavior so may not require diagnosis or treatment in a patient with limited life expectancy. All forms of prostate cancer treatment have potential urinary and sexual side effects, so reducing overdiagnosis and overtreatment are critical public health issues. Because screening has many proven benefits but also significant harms, there are widely disparate guidelines on prostate cancer screening from major organizations worldwide. This issue of the Urologic Clinics will provide insights into the many different prostate cancer guidelines and related policy issues.

This issue of the Urologic Clinics covers stricture, renal injuries, priapism, penile fractures, and bladder injuries. An article covering necessary plastic surgery principles for the urologist is also included. Dr. Allen Morey serves as Guest Editor of this issue on urologic trauma and reconstruction. Dr. Morey has extensive clinical experience in reconstructive urology with emphasis in urethral stricture disease, and urologic trauma.

This issue of Hematology/Oncology Clinics is focused on Prostate Cancer and highlights topics such as: Prevention, Early Detection, Biomarkers, Risk stratification, Imaging in Prostate Cancer, Adjuvant hormonal therapy, Management of patient with biochemical relapse, Management of patient with newly metastatic disease, and Bone Health Management.

Many patients leave the doctor's office feeling frustrated and rushed, with unanswered questions. It's a common concern-that by expediting a patient's visit, doctors may miss important information for the sake of brevity. And for patients seeking to discuss alternative therapies outside of conventional medicine, they especially need time to discuss and confirm the truth of their personal research. In The Unfettered Urologist, readers will learn and benefit from the opinions, intuition, and common sense of Martha B. Boone, M.D. -a urologist with over thirty years of working experience and fifteen years of collegiate study. Those seeking detailed insight into the world of urology will learn what Dr. Boone always wanted to tell her patients, but could never pack into a fifteen minute office visit. The Unfettered Urologist explains: Common urology problems and options for readers to start treatment at home, with the confidence of an experienced specialist Inside information not available in medical texts or medical websites Important questions to facilitate office visits when needed When to save healthcare dollars for prevention and treatment (prior to seeing a doctor) The inner workings of the medical profession and thus be able to better utilize the system True stories of medical scenarios and real-life cases Healing techniques outside of conventional medicine that have worked in conjunction with traditional medicine In some cases, how to avoid invasive procedures Entertaining, informative, and packed with unexpected insight, The Unfettered Urologist leads readers through the health care system with humor and candor.

Surgery for Urinary Incontinence, by Drs. Roger Dmochowski, Mickey M. Karram, and W. Stuart Reynolds, is the ideal way to sharpen your skills in the diagnosis and management of this condition. In this volume in the Female Pelvic Surgery Video Atlas Series, edited by Mickey Karram, MD, detailed discussions and illustrations, case studies, and video footage clarify how to most effectively select and perform a variety of procedures and manage complications. Case-based presentations and videos, narrated by the authors, take you step by step through a variety of procedures, including synthetic biologic slings, suspensions, botox injections, the use of neuromodulation devices, and more Heavily illustrated, quick-reference chapters Discuss all of the possible diagnoses and management options for urinary incontinence problems Case studies describe the clinical history surrounding each case featured in the videos, and demonstrate how to manage a variety of recurrent cases as well as how to avoid and manage complications Online access at; www.expertconsult.com places the full text, videos, and more at your fingertips on any computer or mobile device

The Year Book of Urology brings you abstracts of the articles that reported the year's breakthrough developments in urology, carefully selected from more than 500 journals worldwide. Expert commentaries evaluate the clinical importance of each article and discuss its application to your practice. There's no faster or easier way to stay informed! The Year Book of Urology is published annually in December.

Castrate Resistant Prostate Cancer is advanced disease that has stopped responding to hormone therapy. This issue of the Urologic Clinics focuses on the various forms of therapy including immunotherapy, first line chemotherapy, and novel targeted agents. Articles on defining the diseae and palliative care are also included.

The Year Book of Urology brings you abstracts of the articles that reported the year's breakthrough developments in urology, carefully selected from more than 500 journals worldwide. Expert commentaries evaluate the clinical importance of each article and discuss its application to your practice. There's no faster or easier way to stay informed The Year Book of Urology is published annually in December.

The articles in this issue update important topics in pediatric urology, but also address some of the more controversial clinical topics. Those topics included in this issue are Prenatal Ultrasound and Urological Anomalies, Spina Bifida and Neurogenic Bladder, Inguinal and Genital Anomalies, Voiding Dysfunction, Vesicoureteral Reflux, Hydronephrosis, Urolithiasis in Children, Urinary Tract Infection (UTI) work up, Advances in Surgical Pediatric Urological Armamentarium, Pediatric Urologic Oncology, Pediatric Urological Emergencies, and Circumcision Controversies.

This issue of the Urologic Clinics covers timely topics pertinent to Men's Health, including The Role of Primary Care in Men's Health, Changes in Male Fertility in the Last Two Decades, The Aging Male, and Pre-adolescent issues as risk factors for adult male health.

Chronischer Beckenbodenschmerz (CPPS) ist ein vorwiegend in der Urologie beheimatetes Krankheitsbild, das aber haufig auch interdisziplinar auftreten kann und dann fachubergreifend diagnostiziert und behandelt werden muss. Walter Merkle betrachtet in diesem UEberblick vor allem die urologischen Erscheinungsformen, arbeitet jedoch die interdisziplinaren Zusammenhange ein. Er pladiert an die AErzteschaft, das Krankheitsbild des CPPS verstarkt zu beachten, da dieses oft unzureichend diagnostiziert und behandelt wird. Essentiell ist dabei, sich von der alleinigen Sichtweise aus dem Fachgebiet der Urologie zu loesen und sich unbedingt interdisziplinar auf Empathie, Psychosomatik und Osteopathie sowie Biofeedbacktherapie einzulassen, um erfolgreich diagnostizieren und behandeln zu koennen. Der Autor: Dr. Walter Merkle war im Fachbereich Urologie der Deutschen Klinik fur Diagnostik GmbH in Wiesbaden tatig.

This issue of the Urologic Clinics provides a timely update on Renal Cancer and the evolving treatment standards in urology.? Articles include Contemporary Imaging of the Renal Mass, Surgical Approach to Multifocal Renal Cancers, and Systemic Therapy Prior to Surgery.? Effects of the various existing surgical approaches on long-term renal function is also discussed, along with a review of the current trends in surgical management of renal cancers with specific attention to utilization of laparoscopic approach, partial nephrectomy, ablative technologies and observation.

Uroradiology is an up-to-date, image-oriented reference in the style of a teaching file that has been designed specifically to be of value in clinical practice. All aspects of the imaging of urologic diseases are covered, and case studies illustrate the findings obtained with the relevant imaging modalities in both common and uncommon conditions. Most chapters focus on a particular clinical problem, but normal findings, congenital anomalies, and interventions are also discussed and illustrated. In this second edition, the range and quality of the illustrations have been enhanced, and many schematic drawings have been added to help readers memorize characteristic imaging findings through pattern recognition. The accompanying text is concise and informative. Besides serving as an outstanding aid to differential diagnosis, this book will provide a user-friendly review tool for certification or recertification in radiology.

This volume of the Urologic Clinics covers the indications, controversies, and complications of Lymphadenectomy in Urologic Oncology.? Cancer of the prostate, bladder, testicles, and kidney are covered, along with new imaging modalities and complications of open and minimally invasive lymphadenectomy.