Renal Cell Carcinoma: Clinical Management provides a comprehensive, state-of-the art review of this field, and will serve as a valuable resource for clinicians, surgeons and researchers with an interest in kidney cancer. The volume reviews new data about risk factors for the disease, profiles the new staging system for renal cell carcinoma (RCC), highlights our current understanding of familial syndromes of RCC and their molecular genetics, and provides new perspectives about imaging of renal tumors. For localized disease, a greater appreciation of nephron-sparing approaches and the importance of preservation of renal function is discussed in detail. Advances in surgical techniques are highlighted. For metastatic disease, the molecular biology of kidney cancer is reviewed in a concise and understandable manner, including the data that has fostered novel targeted approaches that have revolutionized management. The several landmark phase III targeted therapy trials published in the last few years are placed in context with respect to current management. Integration of surgery and systemic therapy through cytoreductive and consolidative approaches has yielded provocative data that promises to further advance the field, and major advances in this domain are also be discussed.

PNL is the gold standard for the management of large and/or otherwise complex renal stones. Since its introduction in the seventies PNL has undergone considerable evolution, mainly driven by the improvement in access techniques, endoscopic instrument technology, lithotripsy devices and drainage management. The conventional prone position for PNL has been challenged in the last two decades by a variety of modifications, including the supine and Galdakao-modified supine Valdivia positions, which make simultaneous retrograde working access to the collecting system possible and have proven anesthesiological advantages. The Galdakao-modified supine Valdivia position allowed the development of ECIRS (Endoscopic Combined IntraRenal Surgery), a technique exploiting a combined antegrade and retrograde approach to the upper urinary tract, using both rigid and flexible endoscopes with the related accessories. The synergistic teamwork of ECIRS provides a safe and efficient, minimally-invasive procedure for the treatment of all kinds of urolithiasis. The aim of this book is to share with the urologic community worldwide our experience, our standardization of all the steps, and tips and tricks for the procedure.

Recent advances in the treatment of gynecologic malignancies led to a new worldwide consensus to introduce image guidance to gynecologic radiation therapy, particularly to brachytherapy. The book summarizes the changed practice of management: treatment planning for cervical cancer, not modified for over 60 years, has been shifted to an image-based approach, endometrial cancer management with an increase in the use of chemotherapy and vaginal brachytherapy, and vaginal cancer therapy including image guidance and high-dose delivery with IMRT.

Bladder injection of onabotulinumtoxinA for the treatment of urinary incontinence due to neurogenic detrusor overactivity has recently been approved by regulatory agencies in several EU countries and by the FDA in the United States. This is the first book to focus on the practical application of botulinum toxin (BoNT) in the genitourinary tract. It covers in detail applications of BoNT in the bladder and the prostate and pelvic floor, with reviews of the latest clinical series and techniques in both adults and children. Appendices containing easy-to-read instructions for patients undergoing bladder and prostate BoNT injections are included, in addition to procedural guidelines for nursing staff. The book is written in a concise, clinically relevant style by two leading pioneers in the field, who were the first to undertake comprehensive basic research into the mechanisms underlying the efficacy and potential uses of BoNT within the lower urinary tract.

Non-Invasive Sperm Selection for In Vitro Fertilization summarizes and discusses the relevant literature on the various advanced sperm selection methods used in modern Assisted Reproductive Technologies (ART). Chapters review some of the major unresolved issues in the field, the feasibility and success of the various sperm selection methods, their safety and the effects they have on sperm quality and ART outcomes. The book makes recommendations on clinical applications and future research, while helping to elucidate the benefits and promise of non-invasive sperm selection techniques. A distinguished team of scientists, embryologists, and urologists, with expertise in male infertility and ART, contributes to this original and valuable reference guide meant for academics, researchers, and professionals in the field of reproductive medicine who need an update on the current status of the study and practice of non-invasive sperm selection techniques.

Invasive bladder tumors affect the muscle wall, and have a propensity to metastasize and spread to other areas of the body, and are more likely to be fatal. This book presents state-of-the-art diagnoses and treatments available for bladder cancer that has metastasised into the body. A thorough review of current practice is presented in a full color volume with more than 40 tables and 50 illustrations. The book offers a comprehensive review of the subject, covering epidemiology, screening, diagnostic factors, surgery, chemotherapy and post-operative monitoring. Most chapters are jointly written by a basic researcher and a clinician.

In this second volume, the Biennial Review of Infertility brings together the most up-to-date research and clinical information on male and female infertility, emerging assisted reproductive techniques, and controversial issues in reproductive medicine. This volume includes discussion of cutting-edge topics such as epigenetics, proteomics, and the role of the environment in fertility, as well as insightful evidence-based discussion of common clinical procedures. It is the cumulative effort of a preeminent panel of experts presenting each chapter in a clear and well-balanced manner. Created to provide an ongoing appraisal of current knowledge, the Biennial Review of Infertility stimulates communication amongst all those working to help couples resolve their infertility.

Robotic Renal Surgery: Benign and Cancer Surgery for the Kidneys and Ureters provides a comprehensive review of the role of and technical considerations regarding robotic surgery for conditions of the kidney and associated conditions of the upper urinary tract. In addition to serving as a reference regarding indications, preoperative and postoperative management, complications, and evidence-based outcomes, this text also serves as a practical guide for surgeons in how to perform the complete array of robotic kidney and upper tract surgery. Included are detailed descriptions of positioning, instrumentation, and surgical steps for the surgeon newly adopting robotic surgery or for those refining their techniques. All chapters are written by recognized and published experts in the various techniques, creating an authoritative text on the subject. Robotic Renal Surgery: Benign and Cancer Surgery for the Kidneys and Ureters will be of great value to urologists, robotic surgeons, fellows in urologic oncology or endourology as well as urology residents in training and surgical nurses and other surgery team members involved in these procedures.

Management of the modern reproductive endocrinology and infertility clinic has become very complex. In addition to the medical and scientific aspects, it is crucial that the modern director be aware of of incongruent fields such as marketing, accounting, management, and regulatory issues. Reproductive Endocrinology and Infertility: Integrating Modern Clinical and Laboratory Practice was developed to assist the practicing reproductive endocrinologist and/or laboratory director by providing an overview of relevant scientific, medical, and management issues in a single volume. Experts in all pertinent areas present concise, practical, evidence-based summaries of relevant topics, producing a key resource for physicians and scientists engaged in this exciting field of medicine. As novel technologies continue to amplify, Reproductive Endocrinology and Infertility: Integrating Modern Clinical and Laboratory Practice offers insight into development, and imparts extra confidence to practitioners in handling the many demands presented by their work.

Pediatric Urology: Evidence for Optimal Patient Management provides pediatric urologists the information needed for state-of-the-art patient care. Chapters are organized around pertinent clinical questions within major areas of pediatric urology, answered using the best available data while also reporting areas for which there is poor evidence. The text includes randomized controlled trials and prospective observational studies, tables that summarize important studies, and figures that illustrate algorithms with best options for management and their expected results. With an easy to use format not found in other volumes, Pediatric Urology: Evidence for Optimal Patient Management is an indispensible and unique resource for experienced pediatric urologists, pediatric surgeons, general urologists with an interest in pediatric urology, as well as fellows and residents in training.

In this third volume, the Biennial Review of Infertility brings together the most up-to-date research and clinical information on male and female infertility, emerging assisted reproductive techniques, and controversial issues in reproductive medicine. An impressive panel of contributors presents cutting-edge information in a clear and well-balanced manner. This volume includes hot topics in reproductive medicine including age and its impact on fertility, lifestyle factors and reproductive health, fertility preservation for cancer patients, reproductive tourism and a discussion of clinical research design. The expanded section on controversies allows for point/counterpoint discussion between experts with differing opinions on topics like safety of the ICSI procedure and the role of IUI in modern reproductive medicine. Created to provide an ongoing appraisal of current knowledge, the Biennial Review of Infertility stimulates communication amongst all those working to help couples resolve their infertility.

Minimally Invasive Therapy for Urinary Incontinence and Pelvic Organ Prolapse provides a detailed insight into "when, why, what and how" of various minimally invasive surgical procedures for surgical management of SUI, OAB & POP. The volume provides detailed diagrammatic and pictorial step-by-step descriptions of the techniques and management of complications related to these procedures. This book also presents an up to date, one-stop reference for anything pertaining to MIT of these pelvic disorders. Written by experts in the field, Minimally Invasive Therapy for Urinary Incontinence and Pelvic Organ Prolapse is a comprehensive resource designed for both the urologist and urogynecologist treating patients with urinary disorders and pelvic organ prolapsed, as well as for residents in training.

Bladder Dysfunction in the Adult: The Basis for Clinical Management succinctly describes all that the healthcare professional needs to know when treating lower urinary tract symptoms. The book describes how to assess and treat every group of patients likely to be affected with bladder problems and the underlying mechanisms responsible. Women with stress incontinence, men with enlarged prostates, people with neurological disease and the elderly are all discussed in particular detail. For all professionals treating or learning to treat patients with urinary storage or voiding problems, the concise presentation and thorough coverage provides treatment recommendations and clear explanations. Authored by recognized experts in their respective fields, Bladder Dysfunction in the Adult: The Basis for Clinical Management is a comprehensive resource that allows the reader to develop the knowledge, understanding and confidence to deal with the many clinical challenges of bladder dysfunction.

This new volume fills the gap in the literature as it will guide urologists and pathologists in the proper utilization of a variety of laboratory methods that are currently available to determine the presence, persistence or progression of tumors of the lower urinary tract. The volume emphasizes cytology of the urinary tract which is preferred over other methods (i.e. biochemical, immunological and cytogenetic) for its accuracy, especially for the important high grade tumors. This volume will appeal to urologists as well as pathologists, cytopathologists and related professions. The illustrations, nearly all in color, stress the key points of the text and enhance basic understanding of urothelial and other tumors of the urinary tract.

Urological Emergencies: A Practical Approach, Second Edition provides a concise, evidence based review of common urgent and emergent urological conditions in children and adults. Descriptions of the appropriate diagnostic and therapeutic considerations on topics of traumatic, infectious, obstructive, hemorrhagic, iatrogenic, vascular and congenital urological emergencies in adults and children are provided. The text is organized by pathophysiology rather than organ system, allowing the reader to develop approaches to the care of patients with acute urological conditions based on mechanism of disease. Relevant pathophysiological background and epidemiology are reviewed, necessary diagnostic testing recommended, and detailed medical, surgical and endourological management approaches have been provided. All chapters incorporate published guidelines and best practice recommendations from appropriate organizations including the American Urological Association, the Centers for Disease Control and Prevention, and various International Consultations on Urological Diseases. New or significantly revised chapters in each of the subsections address innovations in trauma care and prevention, new strategies in management of kidney stones, and special care needs of children with acute urological problems. Urological Emergencies: A Practical Approach, Second Edition is of great value to practicing urologists, urology residents, emergency medicine trainees and practitioners, and primary care providers including MD's, PA's, and NP's without immediate access to urological consultation.

Leading national and international urologists in the field of endourology describe standard and advanced endoscopic procedures for treating upper-tract pathology. The authors provide step-by-step instructions for the latest endoscopic procedures, ranging from upper urinary tract calculi and strictures to urothelial cancer. Advanced Endourology: The Complete Clinical Guide offers practicing urologists and urology residents not only a comprehensive, illustrated guide to endourological techniques-particularly the more advanced procedures-but also a practical means to expand the range and scope of the procedures they perform.

Robotic technology has paved the way for new opportunities in pediatric urologic surgery. Where once laparoscopy was restricted to urological conditions in children such as undescended testicles and ambiguous genitalia, robotic techniques are now enabling the completion of greatly needed, more involved procedures. Written by highly respected surgeons, Pediatric Robotic Urology provides a state-of-the-art, comprehensive overview of the precise surgical techniques that are changing the practice of pediatric urologic surgery. Divided in two sections and covering both introductory topics and advanced surgical techniques, Pediatric Robotic Urology also includes myriad illustrations and photographs of intraoperative procedures. Developed for accessible reading, this invaluable title is a concise, yet broad reference that is certain to be of significant value to urologists, surgeons, and all health care providers who care for pediatric urologic patients.

The Atlas of Robotic Urologic Surgery provides a detailed, step-by-step guide to common robotic urologic procedures for the purpose of helping novice surgeons in their transition to robotic surgery and seasoned robotic surgeons to refine their surgical technique and expand their repertoire of robotic procedures. In addition, less commonly performed robotic procedures such as those for male infertility, pelvic organ prolapse, urinary tract reconstruction and pediatrics are included. Each chapter is written by the thought leaders in robotic urologic surgery with descriptive step-by-step text, complimented by figures and intraoperative photographs detailing the nuances of each procedure. Emphasis is placed on operative setup, instrument and equipment needs and surgical techniques for both the primary surgeon as well as the operative assistant. The use of ancillary equipment and robotic instrument and endoscope exchanges are highlighted throughout the procedural text by tables designed to aid surgeons and their teams in improving efficiency. This volume will provide unique insights into robotic urologic surgery and reduce the learning curve of accomplishing these increasingly popular procedures.

The transplant physicians and surgeons at Cleveland Clinic have collaborated to produce, Kidney and Pancreas Transplantation: A Practical Guide. This volume is devoted to kidney and pancreas transplantation and is well grounded in scientific principles, quantitative clinical reasoning, clinical pharmacology, tested clinical practices and overall clinical applicability. Also addressed are key aspects in the initiation, maintenance and sustained growth of viable clinical programs in kidney and pancreas transplantation. Kidney and Pancreas Transplantation: A Practical Guide will be of great value to transplant physicians as well as medical and surgical fellows who intend to pursue an interest in transplantation.

Male Infertility: Problems and Solutions provides a summary of state of the art developments in male infertility for both new and experienced practitioners. Written in a clear, concise and readable style, this volume allows the reader to obtain rapid answers to this challenging medical issue. Special emphasis is placed on diagnostic and treatment algorithms. Topics covered include interpretation of semen analysis and advanced testing, endocrine and genetic evaluation, diagnosis of azoospermia as well as an up-to-date interpretation and analysis of the many new therapies available for the treatment of male factor infertility. Male Infertility: Problems and Solutions provides rapid acquisition of pertinent background and development of management plans through the use of concise discussion and treatment algorithms and thus will be of great value to general urologists, gynecologists, primary care providers and allied health providers who manage infertility in both men as well as women.

Ureteroscopy: Indications, Instrumentation & Technique provides a comprehensive and state-of-the-art review of ureteroscopy and will serve as a valuable resource for urologists throughout the world. The volume provides evidence based outcomes to support the expanding indications for ureteroscopy as well as a strong emphasis on appropriate patient selection. The book also provides detailed recommendations for the step-by-step approach to ureteroscopy from both an instrumentation and techniques perspective. The work is extensively illustrated with endoscopic images and accompanied by a web site of video clips which further highlight the clinical application of available endoscopic techniques. The text also includes highly practical presentations of complex endourologic case presentations with expert analysis and editorial commentary. Example cases would include common but challenging cases of ureteroscopy for transitional cell cancer, horseshoe kidneys, hutch diverticulum, and pregnancy. Ureteroscopy: Indications, Instrumentation & Technique provides a unique and valuable resource in the field of ureteroscopy and will include basic instructions for those currently in training or those who have yet to adapt intrarenal ureteroscopy into their surgical armamentarium. Advanced ureteroscopic approaches are also covered for those wishing to enrich their current clinical expertise.

GU-ITIS is a compilation of expert creativity and opinion based upon critical review of the literature, consensus reports and the author's professional experience. Inflammation and pain caused by infectious etiologies are presented by experts in urological and gastrointestinal fields. Pain syndromes specific to the pelvic floor or genitourinary system are discussed from several perspectives. The book also includes chapters addressing iatrogenic causes of GU inflammation. Management by means of pharmacological, surgical or alternative methods are likewise presented within the context of specific disease entities, as well as separate therapeutic chapters.

Surgical pathology is the cornerstone in the management of neoplastic disorders. Written for the practicing surgical pathologist in mind, Surgical Pathology of Endocrine and Neuroendocrine Tumors provides an up-to-date text on surgical pathology of endocrine and neuroendocrine tumors. The text begins with radiological imaging of tumors, followed by a section on fine needle aspiration biopsy. The main section focuses on surgical pathology of endocrine and neuroendocrine tumors. The volume closes with applications of molecular techniques and their potential for the future. Surgical Pathology of Endocrine and Neuroendocrine Tumors is written by a panel of internationally recognized pathologists who are not only experts in their fields, but who also contribute their own valuable insights making this new book an essential resource for practicing general and specialist surgical pathologists and pathologists in training.

The purpose of this book is to define the basis of telemicrosurgery, a new discipline at the border of robotics and microsurgery. After the history of robotics and microsurgery, the robots and their instrumentation will be described. The chapters will explain the training in telemicrosurgery and then propose some experimental paradigms. The first clinical applications for various specialties will be explored. In closing, potential future applications will be discussed.

This book focuses on the state of the art in fully grasping precocious puberty and its consequences, incorporating advances in the areas of endocrinology, genetics, imaging and therapeutics to offer an indispensable tool for all physicians interested in the latest advances in this field. The authors present the latest findings on early puberty in girls and boys. The dynamic process of maturation is influenced by many signals and reshapes growing children's role within their environment. Readers will benefit from the educational value and level of depth of the individual chapters; written by respected experts and in a self-contained format, they can also be read separately to address specific interests.