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This book covers the latest advances in non-muscle invasive bladder cancer care. It provides a review of the available evidence base for the efficacy of a range of therapeutic techniques, diagnostic procedures and risk factors. Management of Non-Muscle Invasive Bladder Cancer features detailed guidance in uniformly formatted chapters on how to properly apply a range of available therapeutic treatments relevant for patient care. It is a valuable resource for all trainee and practising medical professionals who treat these patients.

This book provides a systematic review of the management and treatment of this disease. The concise and highly structured chapters feature essential background knowledge and commentary on recent advances within each step of a range of patient pathways. Management of Muscle Invasive Bladder Cancer provides a framework for patients' care based on the research, as well as practically and clinically oriented guidelines. This book is relevant to trainees and practicing urologists and oncologists, in addition to medical professionals involved in the treatment of bladder cancer.

Take control of your interstitial cystitis treatment with this comprehensive guide. Interstitial cystitis (IC), also called painful bladder syndrome, is a complex bladder pain condition that can be confusing, frustrating, and debilitating. Successful treatment requires a multidisciplinary approach that often features a combination of medication, physical therapy, dietary and lifestyle changes, alternative medicine, and more. The Interstitial Cystitis Solution has all the information you need, all in one place. It provides scientific reviews and evaluations of potential treatments, along with a helpful treatment plan tailored to your specific symptoms and lifestyle. Written by leading IC expert Nicole Cozean, DPT, PT, WCS, the information is presented in an accessible way, with real-life examples from the author, who has treated hundreds of patients who have found relief from their symptoms with the holistic treatment plan outlined in this book. This comprehensive guide allows you to take control of your healing and will restore sanity to the insane world of conflicting diagnoses, treatments, and advice. Within: Learn about alternatives to medication and surgery Understand the role of the pelvic floor in IC Practice mind-body therapies to manage pain Discover exercises, stretches, and self-care techniques to alleviate symptoms and prevent flares Also included are helpful: Personalized flare-busting plan Symptom log Bladder diary Weekly treatment plan checklist And more! Thousands of patients with IC live healthy, pain-free lives-and so can you!

Prostate cancer is the most common cancer in men in the UK and US and the second most common worldwide. The ABC of Prostate Cancer provides fully illustrated guidance on the treatment and management of prostate cancer. It covers the biology, anatomy, and pathology of prostate cancer, screening, and active surveillance and monitoring. It presents an assessment of treatment options including prostatectomy, bracytherapy, chemotherapy and immunotherapy, along with modern diagnostic tests and an overview of new approaches to prostate cancer. With an international author team, the ABC of Prostate Cancer is ideal for general practitioners, family physicians, specialist nurses, junior doctors, medical students and others working with prostate cancer patients and their families.

The new international standard reference work for sexual medicine
Written under the auspices of the International Society for Sexual Medicine, (www.issm.info), the leading professional society in sexual medicine and founder of the most influential journal in the field, "The Journal of Sexual Medicine, ""published by Blackwell Publishing"
Comprehensive coverage of the full range of diagnostic and treatment options in all aspects of male and female sexual dysfunctions
Provides information on recent progress in pharmacologic approaches, including the highly successful drug treatments for ED
Useful for any part of the patient-clinician consultation, from gathering symptoms to diagnosis to treatment to reports on potential and developing treatments

The purpose of this book is to provide a contemporary overview of the causes and consequences of prostate cancer from a cellular and genetic perspective. Written by experts in the fields of epidemiology, toxicology, cell biology, genetics, genomics, cell-cell interactions, cell signaling, hormone signaling, and transcriptional regulation, the text covers aspects of prostate cancer from disease initiation to metastasis. Chapters explore in depth the cells of origin for prostate cancer, its genomic subtypes, neural transcription factors in disease progression, epigenetic regulation of chromatin, and many other topics. This book distinguishes itself from other texts on prostate cancer by its focus on cellular and genetic mechanisms, as opposed to clinical diagnosis and management. As a result, this book will be of broad interest to basic and translational scientists with familiarity of these topics, as well as to trainees at earlier stages of their research careers.

This book is a basic, practical guide to performing and interpreting state-of-the-art prostate MRI, utilizing the latest guidelines in the field. Prostate MRI has become one of the fastest growing examinations in the radiology practice, and this demand has continuously increased within the past decade. Since it is relatively new, MRI of the prostate is predominantly being performed at academic institutions, however there is a growing demand within the lower-tier health care institutions to offer this examination to their patients. This is an ideal guide for radiologists who want to enhance or initiate prostate MRI service for their referring clinicians and as a manual for technologists and those who are in training. Prostate cancer is the second leading cause of cancer death in men, exceeded only by lung cancer. The best predictor of disease outcome lies with correct diagnosis, which requires precise imaging and diagnostic procedures aided by prostate MRI. Urologists, medical oncologists and radiation oncologists all agree that multi-parametric prostate MRI is essential for evaluation of prostate cancer. However, the technical aspects of prostate MR imaging are not as straightforward as for the other imaging modalities and constantly evolving. Its small size presents a real challenge to the radiologist, who needs to do the T2 and diffusion weighted images and perform a dynamic contrast enhanced sequence correctly. These images may also need to be analyzed on an independent workstation. Due to the absence of a current reference manual, when a radiologist wants to establish a prostate imaging service, he/she needs to attend dedicated prostate MR workshops or dive into the literature search alone, only to get more confused about what to do and how to do it. With this book, expert authors were asked to give clear guidance to those who want to enhance or initiate their prostate imaging service. With this much-needed, concise, practical guidance, radiologists can perform and interpret multi-parametric prostate MRI in a standardized fashion, in concordance with PI-RADS v2.1 that can be applicable to all available hardware platforms (GE, Philips, Siemens, Toshiba). Additionally, they can perform post-processing for possible targeted biopsy and interpret post-therapy and PET studies. The book discusses imaging protocols (planning and prescription) and sequence parameters with representative images for each MRI sequence. This handbook-style practical manual can be used in the radiology reading room by those interpreting the MR exam as a reference as well as at the MRI scanner by the technologists as a guide. Coverage of basic prostate anatomy, pathology, Urologists' point of view, MRI guided radiation treatment planning and molecular imaging is also included. Throughout the book, authors will discuss basics, pitfalls, and provide tips in image acquisition and interpretation, alongside several case examples.

Psychological approaches to sexual health have arisen independently in a variety of different contexts. Psychology of Sexual Health is the first book to draw together the knowledge base and expertise of clinicians and researchers from all disciplines in the psychological management of sexual health. The authors have presented advances in theory and practice in a practical way that will be accessible for all disciplines.

There have been rapid developments in the psychological management of sexually transmitted diseases, particularly HIV and AIDS. A significant proportion of those attending genitourinary clinics do not have a disease or infection, but rather are seeking help with sexual health issues relating to behaviour, prior sexual experiences and relationships. Sexual health problems are being increasingly raised by patients across many other health specialties. Hence an increasing number of practitioners are needing to understand the psychological issues underlying sexual health.

With contributions from experts around the world, this book addresses a wide range of issues including sexually transmitted diseases, sexual abuse, rape, abortion and genetic counselling.

This book is designed to familiarize clinical practitioners in systemic therapy options and medical management of urologic malignancies including prostate cancer, bladder and upper tract urothelial carcinoma, and renal cell carcinoma. Organized by organ system, the text highlights new therapies such as novel forms of androgen deprivation, cytotoxic chemotherapy, immune check point and immunomodulatory agents, and targeted therapies. Written by experts in the field, the book also reviews current chemotherapy and immunotherapy regimens for genitourinary malignancies and discusses indications, outcomes, and toxicities, as well as clinical trial concepts. Each of the book's chapters offers a bulleted box of clinical pearls on the particular role of the APP. Chemotherapy and Immunotherapy in Urologic Oncology: A Guide for the Advanced Practice Provider is a resource for urologists, uro-radiologists, medical clinicians and family practitioners alike, familiarizing its audiences with systemic therapy regimens for urologic malignancies, as well as their expected outcomes and side effects.

Grab your copy of The 5-Minute Urology Consult, 3e for rapid-fire reference in the clinic. This essential, easy-to-read text was designed to aid in the diagnosis and treatment of urologic problems quickly and efficiently. Engineered for crystal clarity, and chock-full of information and action items, the "5-Minute Consult" series includes facts and recommendations as informed by the most current data available, sourced from actual patient consultations and further reviewed by top academics and physicians. An invaluable resource for urologists, this book is perfect for the busy specialist or practitioner who deals with urologic conditions on a daily basis, as well as residents and fellows prepping for their certification exams. Features: Topics include adult and pediatric urology, and the subspecialties of urologic oncology, endourology, female urology, neurourology, andrology, infectious diseases, and renal transplantation International editorial board captured the widest array of diseases and conditions expressed worldwide Over 300 major diseases and conditions, with a lexicon of over 1,300 key concepts, diseases, complaints and conditions Visual algorithms and charts enhance clarity Drug Reference section outlines hundreds of urologic drugs and dosages Readable, two-color design and two-page layout Now with the print edition, enjoy the bundled interactive eBook edition, offering tablet, smartphone, or online access to: Complete content with enhanced navigation A powerful search that pulls results from content in the book, your notes, and even the web Cross-linked pages, references, and more for easy navigation Highlighting tool for easier reference of key content throughout the text Ability to take and share notes with friends and colleagues Quick reference tabbing to save your favorite content for future use

Urological disease affects huge numbers of patients at some point in their lives. Diagnostic techniques are critical to ensure the correct diagnosis is made in a timely manner. A huge number of new technologies have been introduced in recent years to aid in this diagnostic pathway in the form of urine tests, blood tests and imaging modalities. Both urologists and other clinicians interested in urology have struggled to keep up with the rapid evolution of these techniques. This book contains up to date and state of the art contributions from major names in the field. It describes the diagnostic pathways for the key aspects of urological disease. Readers will be able to equate symptoms and signs with the relevant investigations. The book focuses on the diagnostic pathways involved, bringing together international leaders in the field who describe the current status of urological investigation.

Acknowledging the fact that hypospadiology has become a true subspecialty, this unique book highlights and explores current philosophy and different principles and techniques of hypospadias repair. It offers an excellent practical guide to all surgeons involved in the management of this common, but troublesome disease. The aim is to help interested surgeons to develop vision, philosophy and talent rather than just enumerate techniques. It is well illustrated with ample colour diagrams and photographs of various operations together with many technical tips. All surgeons in training will benefit by reading this book in preparing for their higher examinations and their surgical training. There is a wide diversity of opinions, and a large number of operations have been described. Here, the team of world class authors present an expert overview on the management of this condition.

The book provides a reference for years to come, written by world-renowned expert investigators studying sex differences, the role of sex hormones, the systems biology of sex, and the genetic contribution of sex chromosomes to metabolic homeostasis and diseases. In this volume, leaders of the pharmaceutical industry present their views on sex-specific drug discovery. Many of the authors presented at the Keystone Symposium on "Sex and gender factors affecting metabolic homeostasis, diabetes and obesity" to be held in March 2017 in Lake Tahoe, CA. This book will generate new knowledge and ideas on the importance of gender biology and medicine from a molecular standpoint to the population level and to provide the methods to study them. It is intended to be a catalyst leading to gender-specific treatments of metabolic diseases. There are fundamental aspects of metabolic homeostasis that are regulated differently in males and females, and influence both the development of diabetes and obesity and the response to pharmacological intervention. Still, most preclinical researchers avoid studying female rodents due to the added complexity of research plans. The consequence is a generation of data that risks being relevant to only half of the population. This is a timely moment to publish a book on sex differences in diseases as NIH leadership has asked scientists to consider sex as a biological variable in preclinical research, to ensure that women get the same benefit of medical research as men.

In keeping with the aims of other books in this Series the Editors have concentrated on the practical aspects of management -in this case of the urinary tract in patients with spinal cord injury. It is well accepted that the management of such patients is best done by those with special experience in this field. Nevertheless, it is essential that urologists should be well informed on matters relating to the neuropathic urinary tract since not all patients will be managed in special centres and, whether their problems are acute or chronic, the wrong clinical decision can lead them into a lifetime of problems. The plan of this book is directed towards examining particular problems and providing definitive answers. Even in this enlightened age of medical progress there are many clinical situations where there is often a choice of treatment. Readers of this Series will be aware that, despite an apparent abundance of information on a topic, it is sometimes not possible to reach a firm conclusion on a management problem. Keith Parsons and John Fitzpatrick are to be congratulated on ensuring that for this subject there are good clear guidelines. The data in the book are up to date and the excellent approach to the subject makes it a valuable addition to Clinical Practice in Urology.

This book analyzes the basic science and treatment of male factor infertility with Dr. Silber's characteristic honesty and clear thinking. It describes finally what works and what doesn't work. It will inspire everyone in reproductive medicine (Gynecologists, Urologists, Embryologists and Endocrinologists) who wish to better understand male infertility.

The second of two companion books which address the biology and clinical aspects of prostate cancer. This volume, Prostate Cancer: Molecular & Diagnostic Imaging and Treatment Stategies, discusses both classic and the most recent imaging approaches for detection, early diagnosis and treatment of prostate cancer. The companion title, Cell & Molecular Biology of Prostate Cancer, covers classic and modern cell and molecular biology as well as genetics, epigenetics, mitochondrial dysfunctions and apoptosis, cancer stem cells, angiogenesis, progression to metastasis, and treatment strategies including clinical trials related to prostate cancer. Taken together, these volumes form one comprehensive and invaluable contribution to the literature.

This book addresses the most pressing current questions in the management of urologic malignancies. The rapid advances in imaging and molecular markers are placed into a clinical context, with explanation of their effects on prognosis and treatment planning. Similarly, progress in immunotherapy is carefully examined, focusing in particular on the role of immune checkpoint inhibitors in both early- and late-stage urologic malignancies. Looking beyond the improvements in minimally invasive techniques for urologic cancers, the impacts of care coordination pathways and enhanced recovery after surgery protocols are reviewed. Readers will also find enlightening discussion of the decision algorithm for the treatment of early-stage, high-grade bladder cancer, taking into account evidence on the most advanced treatment options and the circumstances in which surgery may need to be expedited. The penultimate chapter discusses the Cancer Genome Atlas project for bladder cancer, and the book closes by considering contemporary medical and surgical management of testicular cancer.

This text provides a comprehensive, state-of-the art review of pharmacotherapy for the overactive bladder, and serve as a valuable resource forclinicians, surgeons, and researchers with an interest in OAB. The early chapters will describe the pathophysiology of OAB, algorithm, and provide the readers with a practical guide for evaluating the OAB patient. The next section describes the unique challenges involved in the study of OAB and helps the reader navigate the complexities of the literature on the topic. All chapters are written by experts in their fields and include the most up-to-date scientific and clinical information. The text includes a review of the clinical guidelines for OAB, and a detailed description of the individual therapies, including antimuscarinics, Beta-3 agonists, (insert comma) and chemodenervation. Extensive tabulation of contemporary literature makes this a matchless resource that provides a detailed account of the current evidence for the use of each of these therapies. The text concludes with chapters on unique populations with OAB, and future directions in the research field.Contemporary Pharmacotherapy of Overactive Bladder unites a unique set of thought leaders in the field of voiding dysfunction to create a comprehensive resource that will be useful for a variety of clinicians who treat OAB, including urologists, urogynecologists, general gynecologists, family practitioners, and geriatricians.

This volume covers classic and modern cell and molecular biology of prostate cancer, as well as novel biomarkers, inflammation, centrosome pathologies, microRNAs, cancer initiation novel biomarkers, inflammation, centrosome pathologies, microRNAs, cancer initiation and genetics, epigenetics, mitochondrial dysfunctions and apoptosis, cancer stem cells, angiogenesis and progression to metastasis, and treatment strategies including clinical trials related to prostate cancer. Cell & Molecular Biology of Prostate Cancer is one of two companion books comprehensively addressing the biology and clinical aspects of prostate cancer. Prostate Cancer: Molecular & Diagnostic Imaging and Treatment Stategies, the companion volume, discusses both classic and the most recent imaging approaches including analysis of needle biopsies, applications of nanoparticle probes and peptide-based radiopharmaceuticals for detection, early diagnosis and treatment of prostate cancer. Taken together, these volumes form one comprehensive and invaluable contribution to the literature.

The European Workshop on Molecular and Cellular Endocrinology of the Testis was organized for the first time at Geilo, Norway, 8-11 April 1980. Since then, these meetings have been held in Holland, France, Italy, England, Sweden/Finland (Aland), Germany, and Bel- gium. This year the circle has been closed: The 9th European Testis Workshop is back in the Norwegian mountains where it all started. The Scientific Committee of the First European Testis Workshop included Dr. H.J. van der Molen (Rotterdam), Dr. V. Hansson (Oslo), Dr. B. Cooke (London), Dr. V. Monesi (Rome), Dr. E.M. Ritzen (Stockholm), and Dr. J.M. Saez (Paris). Since then, two of the founders have left the Scientific Committee. Dr. Monesi died suddenly on 29 December 1979, 3 1/2 months before the first workshop took place. Thus, in spite of being one of the founders, he never experienced a Eu- ropean Testis Workshop. Dr. Mario Stefanini, from the same research institute in Rome, replaced Dr. Monesi on the Scientific Committee. Another founder of this workshop series, Dr. H.J. van der Molen (Rot- terdam), is one of the pioneers in research on molecular endocrinology of the testis in Europe. He left the Scientific Committee due to a change in his scientific career and was replaced by Dr. F.F.G. Rom- merts, whose lectures on "Testomania" have been a characteristic fea- ture of these meetings.

Male urogenital glands (also named male accessory sex glands) have received relatively little attention from electron microscopists, with the possible exception of the prostate gland. Moreover, even though comparative studies have clearly shown that these glands exhibit species-dependent features, very few studies, scattered over various publications, are available on the urogenital glands of man. This volume, the 11th of the series on Electron Microscopy in Biology and Medicine, presents an unprecedented collection of information on the functional microanatomy and cytoarchitecture of these organs in humans. Through the integration of transmission and scanning electron microscopy with a variety of modern techniques, it documents the most important aspects of the histophysiology of these glands from their development to some pathological alterations. In order to cover some key mechanisms of their cell biology, such as the action of sex hormones, the epithelio-mesenchymal interactions, and the dynamic of the secretory process, reports on human organs have been supplemented by some studies on experimental animals. The outstanding level of the contributions and the quality of the illustrations make this book, which has been compiled by some of the world authorities on the topic, a work of reference for students, scientists, and professionals interested in biomedical foundations of andrology, as well as a stimulus for future research in this exciting and relatively neglected chapter of human reproduction.

This text provides a comprehensive, state of the art review of this field and will serve as a resource for urologists, colorectal surgeons, geriatricians, and gynecologists as well as researchers interested in neuromuscular phenomena in the pelvis. The book also reviews new data regarding risk factors for pelvic floor muscle dysfunction and profiles new minimally invasive surgical strategies for well known pelvic disease processes. Each chapter is chock full of data from landmark trials which have been published over the past few years and placed in context with respect to current management techniques for pelvic floor disorders. Written by experts in their field, Pelvic Floor Dysfunction and Pelvic Surgery in the Elderly: An Integrated Approach provides a concise yet comprehensive summary to help guide patient management.

This atlas gathers the most frequent imaging findings concerning alterations that cause infertility in both males and in females. Also, it discusses how the images should be analyzed and described, to serve as a guide for the physicians who request and perform these imaging tests. Infertility is a highly prevalent condition - about 10% of couples are infertile with males and females equally affected. This book offers professionals dealing with infertility, including endocrinologists, gynecologists and urologists, a useful guide to the diagnostic imaging tests that are essential in treating these patients. The Atlas of Imaging in Infertility is a valuable resource for physicians from different specialties managing cases of infertility.

Hypertension: from basic research to clinical practice" contains a unique collection of selected chapters written by experts and enthusiasts engaged in research and treatment of hypertension, a condition that affects around a billion people in the world. The chapters describe fundamental researches at cellular and molecular levels to the science, and art of treatment of the condition in clinical practice. The topics included ranges from pathophysiology of hypertension, through monitoring of hypertension, to the treatment of hypertension in different patient categories. It contains essential background information as well as cutting edge research, and state of the art treatment alternatives in this broad field. From the beginners, and research students to the expert clinicians, and established scientists, everybody has something to learn from this book.