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Books > Medicine > General issues > Public health & preventive medicine > Personal & public health > Dietetics & nutrition
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High Calorie Diet and the Human Brain - Metabolic Consequences of Long-Term Consumption (Hardcover, 2015 ed.)
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High Calorie Diet and the Human Brain - Metabolic Consequences of Long-Term Consumption (Hardcover, 2015 ed.)
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The purpose of this monograph is to present readers with a
comprehensive and cutting edge description of neurochemical effects
of diet (beneficial and harmful effects) in normal human brain and
to discuss how present day diet promotes pathogenesis of stroke,
AD, PD, and depression in a manner that is useful not only to
students and teachers but also to researchers, dietitians,
nutritionists and physicians. A diet in sufficient amount and
appropriate macronutrients is essential for optimal health of human
body tissues. In brain, over-nutrition, particularly with
high-calorie diet, not only alters cellular homeostasis, but also
results in changes in the intensity of signal transduction
processes in reward centers of the brain resulting in food
addiction. Over-nutrition produces detrimental effects on human
health in general and brain health in particular because it
chronically increases the systemic and brain inflammation and
oxidative stress along with induction of insulin resistance and
leptin resistance in the brain as well as visceral organs. Onset of
chronic inflammation and oxidative stress not only leads to obesity
and heart disease, but also promotes type II diabetes and metabolic
syndrome, which are risk factors for both acute neural trauma
(stroke) and chronic age-related neurodegenerative and
neuropsychological disorders, such as Alzheimer disease (AD),
Parkinson disease (PD) and depression.
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