Books > Medicine > Clinical & internal medicine > Haematology
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Basophil and Mast Cell Degranulation and Recovery (Hardcover, 1991 ed.)
Loot Price: R5,785
Discovery Miles 57 850
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Basophil and Mast Cell Degranulation and Recovery (Hardcover, 1991 ed.)
Series: Blood Cell Biochemistry, 4
Expected to ship within 10 - 15 working days
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Basophils and mast cells are similar but unique secretory cells
with a well-documented role in immediate-hypersensitivity
reactions. The presence of these cells in various cell mediated
hypersensitivity reactions, in tissues of multiple diseases, and as
a component of the host reaction to injury and repair in numerous
circumstances is well known. Release of stored and newly generated
mediators of inflammation from basophils and mast cells contributes
to the cascade of pathogenetic events in circumstances under which
these release reactions occur. Despite insights acquired through
studies of these pathologic events, the role of basophils and mast
cells and their secretory products in health is not known. In this
book, I review much of the structural information regarding
basophils and mast cells of multiple species. Ultrastructural
studies of rat mast cells historically precede and quantitatively
exceed similar studies of basophils and mast cells of other
species. Therefore, I first review these background studies as an
entity. Then I discuss the contents of two prominent
organelles-granules and lipid bodies-in basophils and mast cells of
several species. The ultrastructural morphology of basophils and
mast cells in three species is presented in detail to establish
appropriate guidelines for their recognition and to provide general
rules for analysis which are appropriate for the identification of
these cells in other species as well."
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