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Herpes Simplex Virus - Pathogenesis, Immunobiology and Control (Paperback, Softcover reprint of the original 1st ed. 1992)
Loot Price: R2,759
Discovery Miles 27 590
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Herpes Simplex Virus - Pathogenesis, Immunobiology and Control (Paperback, Softcover reprint of the original 1st ed. 1992)
Series: Current Topics in Microbiology and Immunology, 179
Expected to ship within 10 - 15 working days
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Although upstaged by the tragic appearance of the human
immunodeficiency virus, herpes simplex viruses (HSV) types 1 and 2
continue to be major human pathogens against which we lack
acceptable vaccines or other means of immunological control. The
virus is large and complex, coding for 70 or more proteins.
Although many mysteries remain to be unraveled, our knowledge base
regarding genomic organization, gene expression and regulation,
pathogenesis, and immune recog nition of component parts is quite
considerable. Indeed, meet ings devoted entirely to herpesviruses
are conspicuous by their frequency and excellent, yet sometimes
exclusive, attendance. The purpose of this volume is to compile in
a single book a series of reviews by leading investigators that
deal with various aspects of virus-host interactions and which
hopefully will pro vide clues as to how to best manage HSV from an
immunobio logical perspective. Ultimately, one anticipates that a
full under standing of virus-host interaction will lead to
strategies useful for the prevention and control of HSV. The state
of current progress with conventional vaccines is presented, as is
a chapter on intracellular immunization. This latter novel approach
to virus infections comes at approximately the bicentenary of
Jenner's introduction of a successful conventional immunization
strategy."
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