This book provides comprehensive information, both for clinicians
and scientists, on the basic mechanisms, clinical features, and
therapeutic approaches to epilepsy as an inflammatory disease.
Inflammation has been for many years considered as an etiologic
player (and a therapeutic target) for a specific group of
epilepsies. However, it turns out that this concept underestimated
the impact of inflammation in seizure disorders. Many accepted
therapies for non-inflammatory epilepsies act in part as an
inflammatory drug. The CNS actively responds to acute immune
challenges by altering body temperature, stimulating the HPA axis,
as well as up- and down-regulating specific sympathetic pathways.
General
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