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Behavioral Neuroscience of Drug Addiction (Hardcover, 2010 ed.)
Loot Price: R6,945
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Behavioral Neuroscience of Drug Addiction (Hardcover, 2010 ed.)
Series: Current Topics in Behavioral Neurosciences, 3
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Drug addiction is a chronically relapsing mental illness involving
severe motivational disturbances and loss of behavioral control
leading to personal dev- tation. The disorder af?icts millions of
people, often co-occurring with other mental illnesses with
enormous social and economic costs to society. Several decades of
research have established that drugs of abuse hijack the brain's
natural reward substrates, and that chronic drug use causes
aberrant alterations in these rewa- processing systems. Such
aberrations may be demonstrated at the cellular, neu- transmitter,
and regional levels of information processing using either animal
models or neuroimaging in humans following chronic drug exposure.
Behaviorally, these neural aberrations manifest as exaggerated,
altered or dysfunctional expr- sion of learned behavioral responses
related to the pursuit of drug rewards, or to environmental factors
that precipitate craving and relapse during periods of drug
withdrawal. Current research efforts are aimed at understanding the
associative and causal relationships between these neurobiological
and behavioral events, such that treatment options will ultimately
employ therapeutic amelioration of neural de?cits and restoration
of normal brain processing to promote efforts to abstain from
further drug use. The Behavioral Neuroscience of Drug Addiction,
part of the Springer series on Current Topics in Behavioral
Neurosciences, contains scholarly reviews by noted experts on
multiple topics from both basic and clinical neuroscience ?elds.
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