Brain Tumor Pathology: Current Diagnostic Hotspots and Pitfalls (Paperback, 2006 ed.)

Since Bailey and Cushing (1926), all brain tumor classifications have been called histogenetic. The nosographic position that the tumor types progressively acquired in the classification systems derived from the resemblance of tumor cells to those of the cytogenesis, modified whenever new information became available from different biological research fields and especially from molecular genetics. Classically, on the basis of the rough correspondence between the mature/immature aspect of tumor cells and the benign/malignant biological behavior of the tumors, the histological labels contained a prognostic significance. The supposed origin of the tumors was thus a factor for prognosis. Later on, with the concept of anaplasia (Cox, 1933; Kernohan et al., 1949) new criteria were introduced for establishing the malignancy grades of tumors. Immunohistochemistry and later molecular genetics further refined the prognostic diagnoses, substantially increasing the opportunities to recognize the cell origin of tumors, beside revealing the pathogenetic mechanisms. Prognoses became more accurate, as required by the greater and more targeted possibilities of therapy.

General

Imprint:	Springer
Country of origin:	Netherlands
Release date:	September 2014
First published:	2006
Authors:	Davide Schiffer
Dimensions:	235 x 155 x 15mm (L x W x T)
Format:	Paperback
Pages:	272
Edition:	2006 ed.
ISBN-13:	978-9401781794
Categories:	Books > Medicine > Clinical & internal medicine > Neurology & clinical neurophysiology Books > Medicine > Surgery > Neurosurgery Books > Medicine > General issues > Medical equipment & techniques > Medical research Books > Medicine > Other branches of medicine > Pathology > Gross pathology Books > Science & Mathematics > Biology, life sciences > Life sciences: general issues > Neurosciences Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology > General Promotions
LSN:	9401781796
Barcode:	9789401781794

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