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Microbial Infections - Role of Biological Response Modifiers (Paperback, 1992)
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Microbial Infections - Role of Biological Response Modifiers (Paperback, 1992)
Series: Advances in Experimental Medicine and Biology, 319
Expected to ship within 10 - 15 working days
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This volume is based on the Proceedings of the International
Conference on "Microbial Infections: Role of Biological Response
Modifiers" held in Tampa, FL, May 29-31, 1991. The major purpose of
this conference was to bring together in one forum prominent
investigators from around the world studying a variety of microbial
pathogens, including bacteria, viruses, and fungi, and the effects
of biological response modifiers (BRM) on the immune response to
these microorganisms. BRM have been widely utilized in the area of
antitumor resistance and include not only experimental tumor cell
vaccines, but also biologically active substances such as
cytokines, i. e., interferons, tumor necrosis factor, and
interleukins, as well as products from bacteria which influence
host resistance mechanisms. It is the belief of the organizers of
this Conference that it was very timely to discuss in detail BRMs
as they impact on microbial infections per se. It is now widely
accepted that immunocompromised individuals, including those
exposed to immunosuppressive substances such as antimetabolites
used for chemothera py of malignancies, or infectious agents, such
as the human immunodeficiency virus and other viruses which depress
the immune response and, in turn, affect a host so as to become
highly susceptible to opportunistic microorganisms, benefit from
BRM stimulation of their immune system. A wide variety of
immunomodulators are now being studied in terms of treating
infectious diseases, as well as malignancy and autoimmune
diseases."
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