Proteinuria: Basic Mechanisms, Pathophysiology and Clinical Relevance (Paperback, Softcover reprint of the original 1st ed. 2016)

Recent work has begun to elucidate at the molecular level how albumin is handled by the kidney and how albuminuria develops in various proteinuric diseases including minimal change disease and focal segmental glomerulosclerosis. This volume provides a comprehensive overview of the renal handling of albumin - from basic mechanisms to the pathophysiology of proteinuric diseases. In describing the basic mechanisms of albuminuria, a particular highlight will be the focus on advanced imaging techniques such as intravital microscopy that have allowed a detailed "window" into albumin transit through the kidney. The volume will cover the epidemiological studies which show that albuminuria is a strong and independent marker of kidney disease progression and cardiovascular events, the molecular details of albumin handling in the kidney at the level of the glomerulus and the proximal tubule and the pathophysiology of proteinuric diseases including minimal change disease, membranous nephropathy, focal segmental glomerulosclerosis and diabetic nephropathy.

General

Imprint:	Springer International Publishing AG
Country of origin:	Switzerland
Release date:	July 2018
First published:	2016
Editors:	Judith Blaine
Dimensions:	235 x 155 x 8mm (L x W x T)
Format:	Paperback
Pages:	145
Edition:	Softcover reprint of the original 1st ed. 2016
ISBN-13:	978-3-319-82801-5
Categories:	Books > Science & Mathematics > Physics > Nuclear structure physics Books > Medicine > General issues > Medical equipment & techniques > Medical research Books > Medicine > Pre-clinical medicine: basic sciences > Physiology > General Books > Medicine > Clinical & internal medicine > Renal medicine > General Books > Science & Mathematics > Biology, life sciences > Biochemistry > Proteins
LSN:	3-319-82801-0
Barcode:	9783319828015

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