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Cellular Mechanisms of Sensory Processing - The Somatosensory System (Paperback, Softcover reprint of the original 1st ed. 1994)
Loot Price: R2,853
Discovery Miles 28 530
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Cellular Mechanisms of Sensory Processing - The Somatosensory System (Paperback, Softcover reprint of the original 1st ed. 1994)
Series: Nato ASI Subseries H:, 79
Expected to ship within 10 - 15 working days
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Total price: R2,873
Discovery Miles: 28 730
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The research field of somatosensory processing in mammals has
experienced revolutionary changes in recent years. Accumulation of
basic and clinical data has greatly accelerated, and new phenomena
have emerged. With the aid of new, refined methods, molecular and
cellular changes have been described, underlying the signal
transduction-transmission between the internal/external environment
and the central nervous system have been described. The discovery
of the interaction between the nervous and the immune system has,
for example changed our view on the development of inflammatory
diseases, while the cloning of genes encoding different trophic
factors has boosted studies revealing profound changes in the
regeneration of neurons, and induction of changes in phenotype. The
study of the pre-and postsynaptic modulation of transmitter
release, and the examination of the combined effects of amino acid
and peptide transmitters has become recently possible by using
cultured cell lines and in vitro techniques. Although it is in
embryonic state, computational properties of single DRG cells under
normal and pathological conditions are being investigated. Results
soon or later will have a great impact on pain research and
consequently ultimately in clinical pain management. This brief
introduction indicates how our knowledge of the somatosensory
system has increased dramatically recently. However, many
investigators cultivate only a very specific field in the growing
area of somatosensory research and find it difficult to integrate a
more universal knowledge of their work.
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